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Exercise hypertension

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https://www.readbyqxmd.com/read/27909228/divergent-outcomes-of-fructose-consumption-on-exercise-capacity-of-rats-friend-or-foe
#1
Angela Sun, An Huang, Elizabeth Kertowidjojo, Su Song, Thomas H Hintze, Dong Sun
To test the hypothesis that high fructose (HF) consumption divergently affects exercise capability, as a function of feeding duration, rats were fed a normal (as control) or a normal caloric diet with HF for 3, 6, 10 and 30 days respectively, and run on a treadmill. Results show that running distance and work were significantly increased, associated with greater exercise oxygen consumption in rats fed HF for 3 (HF-3D) and 6 days, but were decreased in rats fed HF for 30 days (HF-30D) compared to their respective control rats...
December 1, 2016: Journal of Applied Physiology
https://www.readbyqxmd.com/read/27908565/determinants-of-hyperhomocysteinemia-in-healthy-and-hypertensive-subjects-a-population-based-study-and-systematic-review
#2
REVIEW
Liyuan Han, Yanfen Liu, Changyi Wang, Linlin Tang, Xiaoqi Feng, Thomas Astell-Burt, Qi Wen, Donghui Duan, Nanjia Lu, Guodong Xu, Kaiyue Wang, Lu Zhang, Kaibo Gu, Sihan Chen, Jianping Ma, Tao Zhang, Dingyun You, Shiwei Duan
AIMS: Hyperhomocysteinemia (HHcy) is known to increase the risk of many diseases. Factors influencing HHcy in healthy and hypertensive subjects remain under-researched. METHODS: A large population-based study was conducted in 60 communities from Shenzhen, China. Responses to standardized questions on lifestyle factors and blood samples were collected from all participants after a 12-h overnight fast. Multiple linear and multivariate logistic regressions were used to explore risk factors for HHcy...
November 19, 2016: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/27908251/effects-of-an-outpatient-service-rehabilitation-programme-in-patients-affected-by-pulmonary-arterial-hypertension-an-observational-study
#3
Maurizio Bussotti, Paola Gremigni, Roberto Fe Pedretti, Patrycja Kransinska, Silvia Di Marco, Paola Corbo, Giovanni Marchese, Paolo Totaro, Marinella Sommaruga
BACKGROUND: Pulmonary arterial hypertension (PAH) is a rare disease characterised by a severe impairment of functional status and quality of life (QoL). Use of rehabilitative programmes may help to improve outcomes. The aim of this pre/post test case series was to evaluate the impact of a training program, including sessions of aerobic and resistance exercise, inspiratory muscle reinforcement, slow breathing, relaxation, and psychological support, on functional outcomes. METHODS: Fifteen patients affected by PAH, in World Health Organization (WHO) Functional Class (FC) II or III and in stable clinical condition, were included in a 4-week cardiorespiratory training programme conducted in outpatient service...
November 30, 2016: Cardiovascular & Hematological Disorders Drug Targets
https://www.readbyqxmd.com/read/27906837/different-impacts-of-hypertension-and-diabetes-mellitus-on-all-cause-and-cardiovascular-mortality-in-community-dwelling-older-adults-the-rancho-bernardo-study
#4
Jee-Young Oh, Matthew A Allison, Elizabeth Barrett-Connor
OBJECTIVES: Although the prevalence rates of hypertension (HTN) and diabetes mellitus are slowing in some high-income countries, HTN and diabetes mellitus remain as the two major risk factors for atherosclerotic cardiovascular disease (CVD), the leading cause of death in the United States and worldwide. We aimed to observe the association of HTN and diabetes mellitus with all-cause and CVD mortality in older white adults. METHODS: All community-dwelling Rancho Bernardo Study participants who were at least 55 years old and had carefully measured blood pressure and plasma glucose from 75-g oral glucose tolerance test at the baseline visit (1984-1987, n = 2186) were followed up until death or the last clinic visit in 2013 (median 14...
January 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/27900515/community-based-healthy-aging-interventions-for-older-adults-with-arthritis-and-multimorbidity
#5
Janice C Zgibor, Lei Ye, Robert M Boudreau, Molly B Conroy, Joni Vander Bilt, Elizabeth A Rodgers, Elizabeth A Schlenk, Mini E Jacob, Jane Brandenstein, Steven M Albert, Anne B Newman
Examine the impact of programs led by community health workers on health and function in older adults with arthritis and other health conditions. We conducted a cluster-randomized trial of the Arthritis Foundation Exercise Program (AFEP) enhanced with the "10 Keys"™ to Healthy Aging compared with the AFEP program at 54 sites in 462 participants (mean age 73 years, 88 % women, 80 % white). Trained Community health workers delivered the 10-week programs. Outcomes assessed after 6 months included physical performance [Short Physical Performance Battery (SPPB)], Western Ontario and McMaster Universities (WOMAC) Osteoarthritis Index, and preventive health behaviors...
November 29, 2016: Journal of Community Health
https://www.readbyqxmd.com/read/27899866/paradoxical-hypertension-after-successful-cheatham-platinum-stent-implantation-in-an-adolescent-with-coarctation-of-the-aorta
#6
Yin Ling Tan, Wan-Ling Chih, Jou-Kou Wang, Chun-An Chen
Stent implantation using a Cheatham Platinum (CP) stent for coarctation of the aorta (CoA) is a promising treatment alternative to traditional surgical repair. However, there are no earlier reports in the literature focusing on use of this stent in a Taiwanese patient. Herein we report a 16-year-old boy with CoA presenting with heart murmur and exercise intolerance who underwent successful CP stent placement. However, severe hypertension with arterial blood pressure increasing to 207/104 mmHg occurred four hours after stent implantation...
November 2016: Acta Cardiologica Sinica
https://www.readbyqxmd.com/read/27896702/safety-of-regadenoson-stress-testing-in-patients-with-pulmonary-hypertension
#7
Victor M Moles, Thomas Cascino, Ashraf Saleh, Krasimira Mikhova, John J Lazarus, Michael Ghannam, Hong J Yun, Matthew Konerman, Richard L Weinberg, Edward P Ficaro, James R Corbett, Vallerie V McLaughlin, Venkatesh L Murthy
OBJECTIVES: We sought to determine the safety of regadenoson stress testing in patients with PH. BACKGROUND: PH is increasingly recognized at more advanced ages. As many as one-third of patients with PH have coronary artery disease. Because of their physical limitations, patients with PH are unable to adequately exercise. Regadenoson can potentially have an adverse impact due to their tenuous hemodynamics. Current guidelines suggest performing a coronary angiography in patients with PH who have angina or multiple coronary risk factors...
November 28, 2016: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/27884622/exercise-modulates-the-aortic-renin-angiotensin-system-independently-of-estrogen-therapy-in-ovariectomized-hypertensive-rats
#8
Patrick W Endlich, Erick R G Claudio, Leandro C F Lima, Rogério F Ribeiro Júnior, Antonio A B Peluso, Ivanita Stefanon, Nazaré S Bissoli, Virginia S Lemos, Robson A S Dos Santos, Glaucia R de Abreu
The renin-angiotensin-system is an important component of cardiovascular control and is up-regulated under various conditions, including hypertension and menopause. The aim of this study was to evaluate the effects of swimming training and estrogen therapy (ET) on angiotensin-II (ANG II)-induced vasoconstriction and angiotensin-(1-7) [ANG-(1-7)]-induced vasorelaxation in aortic rings from ovariectomized spontaneously hypertensive rats. Animals were divided into Sham (SH), Ovariectomized (OVX), Ovariectomized treated with E2 (OE2), Ovariectomized plus swimming (OSW) and Ovariectomized treated with E2 plus swimming (OE2+SW) groups...
November 21, 2016: Peptides
https://www.readbyqxmd.com/read/27884229/what-have-we-learned-from-the-genetics-of-hypertension
#9
REVIEW
Friedrich C Luft
Twin studies show that about half the risk of hypertension development is inherited. Mendelian hypertension has elucidated astounding basic pathways contributing to hypertension over (presumably) dietary salt intake or directly through increased peripheral vascular resistance. The Mendelian mutations exercise large effects on blood pressure. Inversely, studying the entire human genome for sources signaling blood pressure has yielded many signals with small effects. Thus far, few loci have been validated or translated into targets...
January 2017: Medical Clinics of North America
https://www.readbyqxmd.com/read/27884004/precapillary-pulmonary-hypertension-and-sleep-disordered-breathing-is-there-a-link
#10
Robert Thurnheer, Silvia Ulrich, Konrad E Bloch
Among patients with sleep apnea the reported prevalence of precapillary pulmonary hypertension (PH) has varied largely, depending on patient selection, disease definition, and associated conditions, in particular chronic pulmonary disease. However, in the absence of comorbidities, PH seems to be rare in patients with sleep apnea. Conversely, sleep-related breathing disorders have been commonly found in patients with PH and they have been associated with an impaired quality of life. Since sleep-related breathing disorders may affect the pulmonary circulation and vice versa, patients with sleep-related breathing disorders should be evaluated for risk factors, symptoms and clinical signs of PH and right ventricular heart failure and patients with PH should be evaluated for sleep apnea...
November 25, 2016: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/27882003/risk-factors-for-deep-venous-thrombosis-of-lower-limbs-in-postoperative-neurosurgical-patients
#11
Qiang Li, Zongxue Yu, Xiao Chen, Jinjun Wang, Guixi Jiang
OBJECTIVES: To detect the risk factors for deep venous thrombosis (DVT) in patients after neurosurgery. METHODS: Three hundred and seventy-six patients treated in the department of neurosurgery of our hospital from February 2013 to November 2015 were reviewed retrospectively. The clinical data including age, gender, hospital stay, operation time, occupation type, hypertension, coronary heart disease, diabetes, smoking status, drinking status, postoperative exercises, malignant tumor, and postoperative hormone or dehydrating agent were collected...
September 2016: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/27881877/exercise-training-attenuates-renovascular-hypertension-partly-via-ras-ros-glutamate-pathway-in-the-hypothalamic-paraventricular-nucleus
#12
Yan Zhang, Xiao-Jing Yu, Wen-Sheng Chen, Hong-Li Gao, Kai-Li Liu, Xiao-Lian Shi, Xiao-Yan Fan, Lin-Lin Jia, Wei Cui, Guo-Qing Zhu, Jin-Jun Liu, Yu-Ming Kang
Exercise training (ExT) has been reported to benefit hypertension; however, the exact mechanisms involved are unclear. We hypothesized that ExT attenuates hypertension, in part, through the renin-angiotensin system (RAS), reactive oxygen species (ROS), and glutamate in the paraventricular nucleus (PVN). Two-kidney, one-clip (2K1C) renovascular hypertensive rats were assigned to sedentary (Sed) or treadmill running groups for eight weeks. Dizocilpine (MK801), a glutamate receptor blocker, or losartan (Los), an angiotensin II type1 receptor (AT1-R) blocker, were microinjected into the PVN at the end of the experiment...
November 24, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27878925/left-ventricular-deformation-at-rest-predicts-exercise-induced-elevation-in-pulmonary-artery-wedge-pressure-in-patients-with-unexplained-dyspnoea
#13
Tor Biering-Sørensen, Mário Santos, Jose Rivero, Shane D McCullough, Erin West, Alexander R Opotowsky, Aaron B Waxman, David M Systrom, Amil M Shah
AIMS: Impaired left ventricular (LV) deformation despite preserved LV ejection fraction (LVEF) is common and predicts outcomes in heart failure with preserved LVEF. We hypothesized that impaired LV deformation at rest is a marker of impaired cardiac systolic and diastolic reserve, and aimed to determine whether resting longitudinal (LS) and circumferential strain (CS) are associated with invasively measured haemodynamic response to exercise in patients with dyspnoea and a normal LVEF...
November 22, 2016: European Journal of Heart Failure
https://www.readbyqxmd.com/read/27875728/exercise-induced-pulmonary-hypertension-by-stress-echocardiography-prevalence-and-correlation-with-right-heart-hemodynamics
#14
Deepika Misra, Ante Kendes, Roxana Sulica, Blase Carabello
OBJECTIVES: The aim of this study was to determine the prevalence of exercise-induced pulmonary hypertension (EIPH) in consecutive subjects referred for stress echocardiography for chest pain or shortness of breath and correlate echocardiographic diagnosis of EIPH with hemodynamics at right heart catheterization (RHC). BACKGROUND: Elevated pulmonary pressure can lead to significant morbidity and mortality. EIPH by ehocardiography has been described in patients with connective tissue disease...
November 9, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27873388/effects-of-sildenafil-on-cardiac-structure-and-function-cardiopulmonary-exercise-testing-and-health-related-quality-of-life-measures-in-heart-failure-patients-with-preserved-ejection-fraction-and-pulmonary-hypertension
#15
Licette C Y Liu, Yoran M Hummel, Peter van der Meer, Rolf M F Berger, Kevin Damman, Dirk J van Veldhuisen, Adriaan A Voors, Elke S Hoendermis
AIMS: We recently showed that sildenafil did not improve pulmonary pressures and exercise capacity in a cohort of patients with heart failure and preserved ejection fraction (HFpEF) and predominantly postcapillary pulmonary hypertension. Here, we present the effects of sildenafil on cardiac structure and function, cardiopulmonary exercise testing, laboratory parameters and health-related quality of life measures. METHODS AND RESULTS: Fifty-two HFpEF patients with pulmonary hypertension (mean pulmonary artery pressure >25 mmHg; pulmonary artery wedge pressure >15 mmHg) were randomized to sildenafil 60 mg three times a day or placebo and treated for 12 weeks...
November 21, 2016: European Journal of Heart Failure
https://www.readbyqxmd.com/read/27868327/communication-and-patient-participation-influencing-patient-recall-of-treatment-discussions
#16
Claude Richard, Emma Glaser, Marie-Thérèse Lussier
CONTEXT: Patient recall of treatment information is a key variable towards chronic disease (CD) management. It is unclear what communication and patient participation characteristics predict recall. OBJECTIVES: To assess what aspects of doctor-patient communication predict patient recall of medication information. To describe lifestyle treatment recall, in CD primary care patients. DESIGN: Observational study within a RCT. SETTING & PARTICIPANTS: Community-based primary care (PC) practices...
November 21, 2016: Health Expectations: An International Journal of Public Participation in Health Care and Health Policy
https://www.readbyqxmd.com/read/27866595/modifiable-healthy-lifestyle-behaviors-10-year-health-outcomes-from-a-health-promotion-program
#17
Daniel W Byrne, Lori A Rolando, Muktar H Aliyu, Paula W McGown, Lisa R Connor, Bradley M Awalt, Marilyn C Holmes, Li Wang, Mary I Yarbrough
INTRODUCTION: Previous studies have examined the impact of healthy lifestyle choices on health-related outcomes; however, given their fragmented, often cross-sectional nature, assessing the relative impact of daily modifiable behaviors on overall long-term outcomes, particularly for a diverse working adult population, remains challenging. METHODS: Relationships between ten self-reported healthy lifestyle behaviors and health outcomes during the subsequent 9 years in a cohort of 10,248 participants enrolled during 2003 in a voluntary workplace wellness program were assessed...
December 2016: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/27865192/effect-of-targeted-therapy-on-circulating-progenitor-cells-in-precapillary-pulmonary-hypertension
#18
Jéssica García-Lucio, Olga Tura-Ceide, Roberto Del Pozo, Isabel Blanco, Sandra Pizarro, Elisabet Ferrer, Marta Díez, Núria Coll-Bonfill, Lucilla Piccari, Víctor I Peinado, Joan Albert Barberà
BACKGROUND: Endothelial dysfunction is key in the development of pulmonary hypertension (PH) and is associated with reduced number of circulating progenitor cells. Studies to date evaluating levels of circulating progenitor cells in PH have provided conflicting results. Current treatment of pulmonary arterial hypertension (PAH) and medical treatment of chronic thromboembolic pulmonary hypertension (CTEPH) targets endothelium dependent signalling pathways. The effect of PAH-targeted therapy on circulating progenitor cells has not been clearly established...
November 9, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27864807/assessing-the-associations-between-awareness-of-myocardial-infarction-symptoms-socioeconomic-factors-and-cardiovascular-disease-risk-factors-through-regression-models
#19
Phoebe Tran, Murray A Mittleman
There are few studies that consider the association between awareness of symptoms of acute myocardial infarction (MI), socioeconomic factors (household income, sex, race/ethnicity, and educational attainment), and cardiovascular (CVD) risk factors. It is important to understand these associations because there is evidence that suggests that disparities in the awareness of MI symptoms lead to disparities in delays in receiving treatment and outcomes of patients with MI. The study was to determine if there are disparities in the awareness of different MI symptoms among different groups with respect to self-reported race, ethnicity, education, age, and income (i...
November 18, 2016: Journal of Racial and Ethnic Health Disparities
https://www.readbyqxmd.com/read/27861249/the-antihypertensive-effects-of-aerobic-versus-isometric-handgrip-resistance-exercise
#20
Garrett I Ash, Beth A Taylor, Paul D Thompson, Hayley V MacDonald, Lauren Lamberti, Ming-Hui Chen, Paulo Farinatti, William J Kraemer, Gregory A Panza, Amanda L Zaleski, Ved Deshpande, Kevin D Ballard, Mohammadtokir Mujtaba, C Michael White, Linda S Pescatello
BACKGROUND: Aerobic exercise reduces blood pressure (BP) on average 5-7 mmHg among those with hypertension; limited evidence suggests similar or even greater BP benefits may result from isometric handgrip (IHG) resistance exercise. METHOD: We conducted a randomized controlled trial investigating the antihypertensive effects of an acute bout of aerobic compared with IHG exercise in the same individuals. Middle-aged adults (n = 27) with prehypertension and obesity randomly completed three experiments: aerobic (60% peak oxygen uptake, 30 min); IHG (30% maximum voluntary contraction, 4 × 2 min bilateral); and nonexercise control...
November 16, 2016: Journal of Hypertension
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