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https://www.readbyqxmd.com/read/28929253/positive-rheotaxis-extended-drop-a-one-step-procedure-to-select-and-recover-sperm-with-mature-chromatin-for-intracytoplasmic-sperm-injection
#1
Hamilton De Martin, Marcello S Cocuzza, Bruno C Tiseo, Guilherme J A Wood, Eduardo P Miranda, Pedro A A Monteleone, José Maria Soares, Paulo C Serafini, Miguel Srougi, Edmund C Baracat
PURPOSE: The purpose of this study was to develop a novel one-step ICSI approach to select sperm with better chromatin maturity than the conventional method. METHODS: This was a pilot diagnostic study, which prospectively recruited men during a 6-month period in a University-affiliated infertility centre. Forty consecutive semen samples were provided for analysis. The positive rheotaxis extended drop (PRED) was set up creating a pressure and viscosity gradient. Each semen sample was divided into four aliquots: one aliquot for density gradient centrifugation (DGC), two aliquots for PRED (fresh semen (PRED-FS) and processed semen (PRED-DGC)), and one aliquot as the control (FS)...
September 19, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/28926670/effect-of-an-age-simulation-suit-on-younger-adults-gait-performance-compared-to-older-adults-normal-gait
#2
Andreas Lauenroth, Stephan Schulze, Anestis Ioannidis, Andreas Simm, Rene Schwesig
Age simulation suits are used to demonstrate typical physical impairments of older age (e.g., strength and sensory losses) in younger individuals. The purpose of the current study was to describe gait performance in different age groups while wearing an age simulation suit. A total of 178 participants ages 18 to 85 (mean age = 50.4 years, SD = 16.4 years) were assigned according to their age decade to four groups with (ages 18 to 59) and two groups without (ages 60 to 85) the aging suit. Gait performance was measured with a gait analysis system (GAITRite(®)) while walking at a self-chosen pace...
September 1, 2017: Research in Gerontological Nursing
https://www.readbyqxmd.com/read/28893202/preliminary-evaluation-of-prototype-footwear-and-insoles-to-optimise-balance-and-gait-in-older-people
#3
Hylton B Menz, Maria Auhl, Shannon E Munteanu
BACKGROUND: Footwear has the potential to influence balance in either a detrimental or beneficial manner, and is therefore an important consideration in relation to falls prevention. The objective of this study was to evaluate balance ability and gait patterns in older women while wearing prototype footwear and insoles designed to improve balance. METHODS: Older women (n = 30) aged 65 - 83 years (mean 74.4, SD 5.6) performed a series of laboratory tests of balance ability (postural sway on a foam rubber mat, limits of stability and tandem walking, measured with the Neurocom® Balance Master) and gait patterns (walking speed, cadence, step length and step width at preferred speed, measured with the GAITRite® walkway) while wearing (i) flexible footwear (Dunlop Volley™), (ii) their own footwear, and (iii) prototype footwear and insoles designed to improve dynamic balance...
September 11, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28893187/does-dual-task-training-improve-walking-performance-of-older-adults-with-concern-of-falling
#4
B Wollesen, S Schulz, L Seydell, K Delbaere
BACKGROUND: Older adults with concerns of falling show decrements of gait stability under single (ST) and dual task (DT) conditions. To compare the effects of a DT training integrating task managing strategies for independent living older adults with and without concern about falling (CoF) to a non-training control group on walking performance under ST and DT conditions. METHODS: Single center parallel group single blind randomized controlled trial with group-based interventions (DT-managing balance training) compared to a control group (Ninety-five independent living older adults; 71...
September 11, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28887827/a-universal-parameterized-gradient-based-method-for-photon-beam-field-size-determination
#5
Sharon Lebron, Guanghua Yan, Jonathan Li, Bo Lu, Chihray Liu
PURPOSE: To propose a universal, parameterized gradient-based method (PGM) for radiation field size determination. METHODS: The PGM locates the beam profile's edge by parameterizing its penumbra region with a modified sigmoid function where the inflection point can be determined in a closed form. The parametrization was validated with filter-flattened (FF), flattening-filter-free (FFF) and wedged profiles measured on two Elekta linac models (Synergy and Versa HD)...
September 9, 2017: Medical Physics
https://www.readbyqxmd.com/read/28884057/fixation-mechanisms-of-nanoparticles-on-substrates-by-electron-beam-irradiation
#6
Daichi Morioka, Tomohiro Nose, Taiki Chikuta, Kazutaka Mitsuishi, Masayuki Shimojo
For applications such as the fabrication of plasmonic waveguides we developed a patterning technique to fabricate an array of nanoparticles on a substrate using focused electron beams (Noriki, T.; Abe, S.;.Kajikawa, K.; Shimojo, M. Beilstein J. Nanotechnol.2015,6, 1010-1015). This technique consists of three steps: Firstly, nanoparticles are placed over the entire surface of a substrate. Secondly, the nanoparticles are fixed on the substrate by focused electron beam irradiation. The electron beam decomposes the organic molecules located around the particle into amorphous carbon...
2017: Beilstein Journal of Nanotechnology
https://www.readbyqxmd.com/read/28876939/seamless-staircase-electrical-contact-to-semiconducting-graphene-nanoribbons
#7
Chuanxu Ma, Liangbo Liang, Zhongcan Xiao, Alexander A Puretzky, Kunlun Hong, Wenchang Lu, Vincent Meunier, J Bernholc, An-Ping Li
Electrical contact to low-dimensional (low-D) materials is a key to their electronic applications. Traditional metal contacts to low-D semiconductors typically create gap states that can pin the Fermi level (EF). However, low-D metals possessing a limited density of states at EF can enable gate-tunable work functions and contact barriers. Moreover, a seamless contact with native bonds at the interface, without localized interfacial states, can serve as an optimal electrode. To realize such a seamless contact, one needs to develop atomically precise heterojunctions from the atom up...
September 8, 2017: Nano Letters
https://www.readbyqxmd.com/read/28869740/30-min-of-treadmill-walking-at-self-selected-speed-does-not-increase-gait-variability-in-independent-elderly
#8
Emmanuel S Da Rocha, Marcos R Kunzler, Maarten F Bobbert, Jacques Duysens, Felipe P Carpes
Walking is one of the preferred exercises among elderly, but could a prolonged walking increase gait variability, a risk factor for a fall in the elderly? Here we determine whether 30 min of treadmill walking increases coefficient of variation of gait in elderly. Because gait responses to exercise depend on fitness level, we included 15 sedentary and 15 active elderly. Sedentary participants preferred a lower gait speed and made smaller steps than the actives. Step length coefficient of variation decreased ~16...
September 4, 2017: Journal of Sports Sciences
https://www.readbyqxmd.com/read/28843930/gait-and-its-components-in-typically-developing-preschoolers
#9
Evi Verbecque, Luc Vereeck, Paul Van de Heyning, Ann Hallemans
OBJECTIVES: To determine whether key spatio-temporal components of gait can be identified in children who are preschoolers. Subsequently the obtained components were correlated to results of functional balance tests to determine which of them are related to balance control. METHODS: Thirty-three typically developing children performed gait on treadmill at three speeds (range 2-4.5km/h), the Pediatric Balance Scale (PBS) and the Timed Up and Go test (TUG). Principal component analysis (PCA) with varimax rotation was performed to detect relations between means and variability of step time, -length and -width, walking speed, age, BMI and leg length...
August 12, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28838858/predictive-and-concurrent-validity-of-cartilage-thickness-change-as-a-marker-of-knee-osteoarthritis-progression-data-from-the-osteoarthritis-initiative
#10
W Wirth, D J Hunter, M C Nevitt, L Sharma, C K Kwoh, C Ladel, F Eckstein
OBJECTIVE: To investigate the predictive and concurrent validity of magnetic resonance imaging (MRI)-based cartilage thickness change between baseline (BL) and year-two (Y2) follow-up (predictive validity) and between Y2 and Y4 follow-up (concurrent validity) for symptomatic and radiographic knee osteoarthritis (OA) progression during Y2→Y4. METHODS: 777 knees from 777 Osteoarthritis Initiative (OAI) participants (age: 61.3 ± 9.0 years, BMI: 30.1 ± 4.8 kg/m(2)) with Kellgren Lawrence (KL) grade 1-3 at Y2 (visit before progression interval) had cartilage thickness measurements from 3T MRI at BL, Y2 (n = 777), and Y4 (n = 708)...
August 31, 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/28820904/parametric-studies-of-metabolic-cooperativity-in-escherichia-coli-colonies-strain-and-geometric-confinement-effects
#11
Joseph R Peterson, John A Cole, Zaida Luthey-Schulten
Characterizing the complex spatial and temporal interactions among cells in a biological system (i.e. bacterial colony, microbiome, tissue, etc.) remains a challenge. Metabolic cooperativity in these systems can arise due to the subtle interplay between microenvironmental conditions and the cells' regulatory machinery, often involving cascades of intra- and extracellular signalling molecules. In the simplest of cases, as demonstrated in a recent study of the model organism Escherichia coli, metabolic cross-feeding can arise in monoclonal colonies of bacteria driven merely by spatial heterogeneity in the availability of growth substrates; namely, acetate, glucose and oxygen...
2017: PloS One
https://www.readbyqxmd.com/read/28820891/scene-text-detection-via-extremal-region-based-double-threshold-convolutional-network-classification
#12
Wei Zhu, Jing Lou, Longtao Chen, Qingyuan Xia, Mingwu Ren
In this paper, we present a robust text detection approach in natural images which is based on region proposal mechanism. A powerful low-level detector named saliency enhanced-MSER extended from the widely-used MSER is proposed by incorporating saliency detection methods, which ensures a high recall rate. Given a natural image, character candidates are extracted from three channels in a perception-based illumination invariant color space by saliency-enhanced MSER algorithm. A discriminative convolutional neural network (CNN) is jointly trained with multi-level information including pixel-level and character-level information as character candidate classifier...
2017: PloS One
https://www.readbyqxmd.com/read/28818453/two-locus-clines-on-the-real-line-with-a-step-environment
#13
Reinhard Bürger
The shape of allele-frequency clines maintained by migration-selection balance depends not only on the properties of migration and selection, but also on the dominance relations among alleles and on linkage to other loci under selection. We investigate a two-locus model in which two diallelic, recombining loci are subject to selection caused by an abrupt environmental change. The habitat is one-dimensional and unbounded, selection at each locus is modeled by step functions such that in one region one allele at each locus is advantageous and in the other deleterious...
August 14, 2017: Theoretical Population Biology
https://www.readbyqxmd.com/read/28816566/five-year-motor-functional-outcome-in-children-with-acquired-brain-injury-yet-to-the-end-of-the-story
#14
Elena Beretta, Erika Molteni, Sara Galbiati, Giuseppe Stefanoni, Sandra Strazzer
PURPOSE: The description of motor changes and clinical evolution of a pediatric cohort with acquired brain injury (ABI) over 5 years by the functional independence measure for children (WeeFIM). METHODS: We analyzed retrospective data from 496 patients (aged 0-18 years) with severe ABI admitted for rehabilitation. WeeFIM scores and disability rating scale (reference scale) were collected at admission, discharge and yearly, up to year 5. RESULTS: Functional limitations gradually reduced after ABI, but children still had residual disabilities at the endpoint...
August 17, 2017: Developmental Neurorehabilitation
https://www.readbyqxmd.com/read/28810990/gait-and-functional-outcomes-for-young-active-males-with-traumatic-unilateral-transfemoral-limb-loss
#15
Caitlin E Mahon, Alison L Pruziner, Brad D Hendershot, Erik J Wolf, Benjamin J Darter, K Bo Foreman, Joseph B Webster
OBJECTIVE: Altered body structures that occur with the loss of a lower limb can impact mobility and quality of life. Specifically, biomechanical changes that result from wearing a prosthesis have been associated with an increased risk of falls or joint degeneration, as well as increased energy demands. While previous studies describing these outcomes are typically limited by number of outcome measures and/or small, diverse patient groups, recent military conflicts present a unique opportunity to collect outcomes from a relatively homogenous, active patient population with limb loss...
July 2017: Military Medicine
https://www.readbyqxmd.com/read/28803217/accurate-model-based-segmentation-of-gynecologic-brachytherapy-catheter-collections-in-mri-images
#16
Andre Mastmeyer, Guillaume Pernelle, Ruibin Ma, Lauren Barber, Tina Kapur
The gynecological cancer mortality rate, including cervical, ovarian, vaginal and vulvar cancers, is more than 20,000 annually in the US alone. In many countries, including the US, external-beam radiotherapy followed by high dose rate brachytherapy is the standard-of-care. The superior ability of MR to visualize soft tissue has led to an increase in its usage in planning and delivering brachytherapy treatment. A technical challenge associated with the use of MRI imaging for brachytherapy, in contrast to that of CT imaging, is the visualization of catheters that are used to place radiation sources into cancerous tissue...
July 18, 2017: Medical Image Analysis
https://www.readbyqxmd.com/read/28798839/paper-based-microfluidic-devices-by-asymmetric-calendaring
#17
S Oyola-Reynoso, C Frankiewicz, B Chang, J Chen, J-F Bloch, M M Thuo
We report a simple, efficient, one-step, affordable method to produce open-channel paper-based microfluidic channels. One surface of a sheet of paper is selectively calendared, with concomitant hydrophobization, to create the microfluidic channel. Our method involves asymmetric mechanical modification of a paper surface using a rolling ball (ball-point pen) under a controlled amount of applied stress (σz) to ascertain that only one side is modified. A lubricating solvent (hexane) aids in the selective deformation...
January 2017: Biomicrofluidics
https://www.readbyqxmd.com/read/28790476/surgical-treatment-of-sanders-type-2-calcaneal-fractures-using-a-sinus-tarsi-approach
#18
Chul Hyun Park, Dong Yeol Lee
BACKGROUND: Calcaneum is the most commonly fractured tarsal bone. The optimal treatment for displaced calcaneus fractures involving the posterior facet is surgical. The extensile lateral approach is commonly preferred because it provides sufficient exposure of the subtalar facet. However, this technique has the risk of complications such as wound necrosis and sural nerve injury. Various minimally invasive approaches, such as sinus tarsi approach, limited posterior approach, and percutaneous approach, have been introduced to reduce possible complications...
July 2017: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/28783556/foot-structure-is-significantly-associated-to-subtalar-joint-kinetics-and-mechanical-energetics
#19
Jayishni N Maharaj, Andrew G Cresswell, Glen A Lichtwark
INTRODUCTION/AIM: Foot structure has been implicated as a risk factor of numerous overuse injuries, however, the mechanism linking foot structure and the development of soft-tissue overuse injuries are not well understood. The aim of this study was to identify factors that could predict foot function during walking. METHODS: A total of eleven variables (including measures of foot structure, anthropometry and spatiotemporal gait characteristics) were investigated for their predictive ability on identifying kinematic, kinetic and energetic components of the foot...
July 21, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28777545/a-nose-for-hydrogen-gas-fast-sensitive-h2-sensors-using-electrodeposited-nanomaterials
#20
Reginald M Penner
Hydrogen gas (H2) is odorless and flammable at concentrations above 4% (v/v) in air. Sensors capable of detecting it rapidly at lower concentrations are needed to "sniff" for leaked H2 wherever it is used. Electrical H2 sensors are attractive because of their simplicity and low cost: Such sensors consist of a metal (usually palladium, Pd) resistor. Exposure to H2 causes a resistance increase, as Pd metal is converted into more resistive palladium hydride (PdHx). Sensors based upon Pd alloy films, developed in the early 1990s, were both too slow and too insensitive to meet the requirements of H2 safety sensing...
August 4, 2017: Accounts of Chemical Research
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