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https://www.readbyqxmd.com/read/28437760/the-effects-of-object-height-and-visual-information-on-the-control-of-obstacle-crossing-during-locomotion-in-healthy-older-adults
#1
Sho Kunimune, Shuichi Okada
In order to safely avoid obstacles, humans must rely on visual information regarding the position and shape of the object obtained in advance. The present study aimed to reveal the duration of obstacle visibility necessary for appropriate visuomotor control during obstacle avoidance in healthy older adults. Participants included 13 healthy young women (mean age: 21.5±1.4years) and 15 healthy older women (mean age: 68.5±3.5years) who were instructed to cross over an obstacle along a pressure-sensitive pathway at a self-selected pace while wearing liquid crystal shutter goggles...
April 13, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28436590/identification-of-small-molecules-using-accurate-mass-ms-ms-search
#2
REVIEW
Tobias Kind, Hiroshi Tsugawa, Tomas Cajka, Yan Ma, Zijuan Lai, Sajjan S Mehta, Gert Wohlgemuth, Dinesh Kumar Barupal, Megan R Showalter, Masanori Arita, Oliver Fiehn
Tandem mass spectral library search (MS/MS) is the fastest way to correctly annotate MS/MS spectra from screening small molecules in fields such as environmental analysis, drug screening, lipid analysis, and metabolomics. The confidence in MS/MS-based annotation of chemical structures is impacted by instrumental settings and requirements, data acquisition modes including data-dependent and data-independent methods, library scoring algorithms, as well as post-curation steps. We critically discuss parameters that influence search results, such as mass accuracy, precursor ion isolation width, intensity thresholds, centroiding algorithms, and acquisition speed...
April 24, 2017: Mass Spectrometry Reviews
https://www.readbyqxmd.com/read/28433868/effects-of-attentional-focus-on-walking-stability-in-elderly
#3
Jonathan L A de Melker Worms, John F Stins, Erwin E H van Wegen, Sabine M P Verschueren, Peter J Beek, Ian D Loram
INTRODUCTION: Balance performance in the elderly is related to psychological factors such as attentional focus. We investigated the effects of internal vs. external focus of attention and fall history on walking stability in healthy older adults. METHOD: Walking stability of twenty-eight healthy older adults was assessed by applying random unilateral decelerations on a split-belt treadmill and analysing the resulting balance recovery movements. The internal focus instruction was: concentrate on the movement of your legs, whereas the external focus instruction was: concentrate on the movement of the treadmill...
April 4, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28426159/open-microfluidic-gel-electrophoresis-rapid-and-low-cost-separation-and-analysis-of-dna-at-the-nanoliter-scale
#4
Ludwig Gutzweiler, Tobias Gleichmann, Laurent Tanguy, Peter Koltay, Roland Zengerle, Lutz Riegger
Gel electrophoresis is one of the most applied and standardized tools for separation and analysis of macromolecules and their fragments in academic research and in industry. In this work we present a novel approach for conducting on-demand electrophoretic separations of DNA molecules in open microfluidic (OM) systems on planar polymer substrates. The approach combines advantages of slab gel, capillary- & chip-based methods offering low consumable costs (<0.1 $) circumventing cost intensive microfluidic chip fabrication, short process times (5 minutes per analysis) and high sensitivity (4 ng/μl dsDNA) combined with reasonable resolution (17 bases)...
April 20, 2017: Electrophoresis
https://www.readbyqxmd.com/read/28410413/validation-of-enhanced-kinect-sensor-based-motion-capturing-for-gait-assessment
#5
Björn Müller, Winfried Ilg, Martin A Giese, Nicolas Ludolph
Optical motion capturing systems are expensive and require substantial dedicated space to be set up. On the other hand, they provide unsurpassed accuracy and reliability. In many situations however flexibility is required and the motion capturing system can only temporarily be placed. The Microsoft Kinect v2 sensor is comparatively cheap and with respect to gait analysis promising results have been published. We here present a motion capturing system that is easy to set up, flexible with respect to the sensor locations and delivers high accuracy in gait parameters comparable to a gold standard motion capturing system (VICON)...
2017: PloS One
https://www.readbyqxmd.com/read/28409775/optical-pump-rejection-filter-based-on-silicon-sub-wavelength-engineered-photonic-structures
#6
Diego Pérez-Galacho, Carlos Alonso-Ramos, Florent Mazeas, Xavier Le Roux, Dorian Oser, Weiwei Zhang, Delphine Marris-Morini, Laurent Labonté, Sébastien Tanzilli, Éric Cassan, Laurent Vivien
The high index contrast of the silicon-on-insulator (SOI) platform allows the realization of ultra-compact photonic circuits. However, this high contrast hinders the implementation of narrow-band Bragg filters. These typically require corrugation widths of a few nanometers or double-etch geometries, hampering device fabrication. Here we report, for the first time, to the best of our knowledge, on the realization of SOI Bragg filters based on sub-wavelength index engineering in a differential corrugation width configuration...
April 15, 2017: Optics Letters
https://www.readbyqxmd.com/read/28400615/the-neuromuscular-origins-of-kinematic-variability-during-perturbed-walking
#7
Heather E Stokes, Jessica D Thompson, Jason R Franz
We investigated the neuromuscular contributions to kinematic variability and thus step to step adjustments in posture and foot placement across a range of walking speeds in response to optical flow perturbations of different amplitudes using a custom virtual environment. We found that perturbations significantly increased step width, decreased step length, and elicited larger trunk sway compared to normal walking. However, perturbation-induced effects on the corresponding variabilities of these measurements were much more profound...
April 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28397621/performance-of-holstein-calves-receiving-equal-quantities-of-milk-at-fixed-or-variable-amounts-per-day-during-milk-feeding-period
#8
M Khani, F Ahmadi, M Ariana, S Omidian, S Sharifi, M H Ghaffari, H Beiranvand
Two experiments were conducted to determine the effects of feeding equal quantities of milk during the pre-weaning period through different milk-feeding regimes on calf growth, starter intake and selected blood metabolites. In experiment 1, 44 female Holstein calves (3 days of age and 39.2±4.3 kg of BW) were distributed randomly to one of two milk-feeding programs (1 calf per pen; 22 pens per treatment group): (1) consistent (CONS; 6 l/day of milk from days 3 to 60 and 3 l/day from days 61 to 65 of age) or (2) step-up/step-down (SUSD; 5 l/day of milk from days 3 to 15, 8 l/day from days 16 to 40, 6 l/day from days 41 to 50, 3 l/day from days 51 to 60 and then 2 l/day from days 61 to 65 of age)...
April 11, 2017: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/28394674/the-effect-of-visual-environmental-distraction-on-gait-performance-in-children
#9
F Bizama, A Medley, E Trudelle-Jackson, L Csiza
PURPOSE: Identify the effect of visual distraction on gait parameters in children and describe the role of walking experience (WE) in the management of visual distraction. METHODS: Forty-two typically developing children, mean age 43.2 months (SD = 22.9) participated and were divided into three groups according to WE: early walkers (6-11 months of WE), preschool walkers (12-37 months of WE), and experienced walkers (38-79 months of WE). Gait parameters measured under two conditions (no visual distraction and with visual distraction) included: velocity, step length, step width, and double limb support percentage (DLS%) of gait cycle...
April 10, 2017: Physical & Occupational Therapy in Pediatrics
https://www.readbyqxmd.com/read/28388793/treating-the-deviated-or-wide-nasal-dorsum
#10
Richard E Davis, Allen I Foulad
Both deviation and excessive width of the nasal dorsum result in conspicuous facial disharmony and are often attended by nasal airway dysfunction. Whether the result of developmental growth disturbances, nasal trauma, failed nasal surgery, or combinations therein, deviation and splaying of the nasal dorsum can be exceedingly difficult to treat. Individualized treatment is paramount because contour variations are seemingly endless, and a careful preoperative assessment of the anatomic, physiologic, cosmetic, and psychosocial factors that characterize the deformity is necessary to devise an effective patient-specific treatment plan...
April 2017: Facial Plastic Surgery: FPS
https://www.readbyqxmd.com/read/28380321/gait-analysis-and-clinical-correlations-in-early-parkinson-s-disease
#11
M Pistacchi, M Gioulis, F Sanson, E De Giovannini, G Filippi, F Rossetto, S Zambito Marsala
The aim of our study was to identify and quantify spatiotemporal and kinematic gait parameters obtained by 3D gait analysis (GA) in a group of Parkinson's disease (PD) patients compared with healthy subjects in order to investigate whether early PD patients could present an abnormal gait pattern. Forty-four patients affected by early-stage PD compared with a control group were analyzed. All participants were evaluated with 3D GA in the gait laboratory. The greatest significance in temporal parameters was found in cadence (102...
January 2017: Functional Neurology
https://www.readbyqxmd.com/read/28374350/teaching-the-basics-development-and-validation-of-a-distal-radius-reduction-and-casting-model
#12
Mark A Seeley, Peter D Fabricant, J Todd R Lawrence
BACKGROUND: Approximately one-third of reduced pediatric distal radius fractures redisplace, resulting in further treatment. Two major modifiable risk factors for loss of reduction are reduction adequacy and cast quality. Closed reduction and immobilization of distal radius fractures is an Accreditation Council for Graduate Medical Education residency milestone. Teaching and assessing competency could be improved with a life-like simulation training tool. QUESTIONS/PURPOSES: Our goal was to develop and validate a realistic distal radius fracture reduction and casting simulator as determined by (1) a questionnaire regarding the "realism" of the model and (2) the quantitative assessments of reduction time, residual angulation, and displacement...
April 3, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28373575/unveiling-the-carrier-transport-mechanism-in-epitaxial-graphene-for-forming-wafer-scale-single-domain-graphene
#13
Sang-Hoon Bae, Xiaodong Zhou, Seyoung Kim, Yun Seog Lee, Samuel S Cruz, Yunjo Kim, James B Hannon, Yang Yang, Devendra K Sadana, Frances M Ross, Hongsik Park, Jeehwan Kim
Graphene epitaxy on the Si face of a SiC wafer offers monolayer graphene with unique crystal orientation at the wafer-scale. However, due to carrier scattering near vicinal steps and excess bilayer stripes, the size of electrically uniform domains is limited to the width of the terraces extending up to a few microns. Nevertheless, the origin of carrier scattering at the SiC vicinal steps has not been clarified so far. A layer-resolved graphene transfer (LRGT) technique enables exfoliation of the epitaxial graphene formed on SiC wafers and transfer to flat Si wafers, which prepares crystallographically single-crystalline monolayer graphene...
April 3, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28373013/effects-of-socket-size-on-metrics-of-socket-fit-in-trans-tibial-prosthesis-users
#14
Joan E Sanders, Robert T Youngblood, Brian J Hafner, John C Cagle, Jake B McLean, Christian B Redd, Colin R Dietrich, Marcia A Ciol, Katheryn J Allyn
The purpose of this research was to conduct a preliminary effort to identify quantitative metrics to distinguish a good socket from an oversized socket in people with trans-tibial amputation. Results could be used to inform clinical practices related to socket replacement. A cross-over study was conducted on community ambulators (K-level 3 or 4) with good residual limb sensation. Participants were each provided with two sockets, a duplicate of their as-prescribed socket and a modified socket that was enlarged or reduced by 1...
March 31, 2017: Medical Engineering & Physics
https://www.readbyqxmd.com/read/28373000/abdominoplasty-in-prune-belly-syndrome-modifications-in-monfort-technique-to-address-variable-patterns-of-abdominal-wall-weakness
#15
Edwin A Smith, Arun Srinivasan, Hal C Scherz, Anthony J Tracey, Bruce Broecker, Andrew J Kirsch
INTRODUCTION: Abdominoplasty is an important component of the management of children with prune belly syndrome (PBS). While there are features of the abdominal defect in PBS which are common to all patients, there will be differences unique to each patient that should be taken into consideration in surgical planning. Specifically, we have come to realize that although the Monfort procedure assumes a symmetric pattern of abdominal wall laxity, this symmetry is rarely present. OBJECTIVE: The aim of this report is to describe our modifications and review our outcomes for the Monfort procedure which more completely address correction of the abdominal wall laxity including both common and uncommon features while positioning the umbilicus to a more anatomically correct position (Figure)...
March 22, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28372421/an-all-solid-state-microsecond-range-quasi-square-pulse-generator-based-on-fractional-turn-ratio-saturable-pulse-transformer-and-anti-resonance-network
#16
Rong Chen, Jianhua Yang, Xinbing Cheng, Zilong Pan
High voltage pulse generators are widely applied in a number of fields. Defense and industrial applications stimulated intense interests in the area of pulsed power technology towards the system with high power, high repetition rate, solid state characteristics, and compact structure. An all-solid-state microsecond-range quasi-square pulse generator based on a fractional-turn ratio saturable pulse transformer and anti-resonance network is proposed in this paper. This generator consists of a charging system, a step-up system, and a modulating system...
March 2017: Review of Scientific Instruments
https://www.readbyqxmd.com/read/28371740/the-high-cost-of-swing-leg-circumduction-during-human-walking
#17
K Alex Shorter, Amy Wu, Arthur D Kuo
Humans tend to walk economically, with preferred step width and length corresponding to an energetic optimum. In the case of step width, it is costlier to walk with either wider or narrower steps than normally preferred. Wider steps require more mechanical work to redirect the body's motion laterally with each step, but the cost for narrower steps remains unexplained. Here we show that narrow steps are costly because they require the swing leg to be circumducted around the stance leg. Healthy adults (N=8) were tested walking with varying levels of circumduction, induced through lightweight, physical obstructions ("Fins") attached medially to the lower legs, during treadmill walking at fixed speed (1...
March 23, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28371662/do-kinematic-metrics-of-walking-balance-adapt-to-perturbed-optical-flow
#18
Jessica D Thompson, Jason R Franz
Visual (i.e., optical flow) perturbations can be used to study balance control and balance deficits. However, it remains unclear whether walking balance control adapts to such perturbations over time. Our purpose was to investigate the propensity for visuomotor adaptation in walking balance control using prolonged exposure to optical flow perturbations. Ten subjects (age: 25.4±3.8years) walked on a treadmill while watching a speed-matched virtual hallway with and without continuous mediolateral optical flow perturbations of three different amplitudes...
March 31, 2017: Human Movement Science
https://www.readbyqxmd.com/read/28363548/in-situ-deposition-of-cu2o-micro-needles-for-biologically-active-textiles-and-their-release-properties
#19
Hossam E Emam, Hanan B Ahmed, Thomas Bechtold
Metal/metal oxide containing fibres are gradually increasing in textile industrialization recently, owing to their high potential for application as antimicrobial textiles. In this study, the reducing properties of cellulose were applied to synthesize cuprous oxide in-situ. The direct formation of Cu2O on viscose fabrics was achieved via quite simple technique in two subsequent steps: alkalization and sorption. Cu contents in fabrics before and after rinsing ranged between 45.2-86.4mmol/kg and 18.1-67.7mmol/kg, respectively...
June 1, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28350243/fitts-theorem-and-movement-time-dissociation-for-amplitude-and-width-manipulations-replying-to-hoffmann
#20
Matthew Heath, Luc Tremblay, Digby Elliott
The commentary by Errol Hoffmann asserts that previous work by our group provides the spurious conclusion that amplitude and width manipulations to a movement environment elicit dissociable relations between movement time (MT) and P. M. Fitts' (1954) index of difficulty (ID). Hoffmann concludes that any such dissociation is the result of actions evoked entirely as ballistic. In this reply, we demonstrate that Hoffmann's commentary is a clear misrepresentation of the study goals and conclusions stated by our group...
March 28, 2017: Journal of Motor Behavior
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