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https://www.readbyqxmd.com/read/29128834/preparation-of-nano-caco3-polystyrene-nanocomposite-beads-for-efficient-bilirubin-removal
#1
Jian Chen, Guanghui Cheng, Yamin Chai, Wenyan Han, Wenhui Zong, Jie Chen, Chunran Li, Weichao Wang, Lailiang Ou, Yaoting Yu
A novel nano-CaCO3/polystyrene nanocomposite adsorbent (NPS-8) was synthesized for efficient bilirubin removal from human plasma. A comparison with the polystyrene adsorbent (PS-8), which was without the incorporation of nano-CaCO3, revealed that NPS-8 had superior bilirubin adsorption capacity and mechanical strength. The resulting nano-CaCO3 reinforced PS-8 (NPS-8) was tested by transmission electron microscopy (TEM), scanning electron microscopy (SEM), mechanical strength test, and bilirubin adsorption assays...
November 8, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/29095763/effects-of-malignancy-on-blood-coagulation-in-septic-intensive-care-patients
#2
Ecaterina Scărlătescu, Marcus D Lancé, Nathan J White, Stefan S Aramă, Dana R Tomescu
: The objectives of the study are to examine the effect of sepsis on the coagulation profile of patients having solid cancer and to test the hypothesis that septic patients with cancer have normal or increased hemostatic capacity despite prolonged standard coagulation tests (SCTs) compared with noninfected cancer patients. Patients with solid cancer were included in the study forming two groups: study group included patients with sepsis with minimum two organ dysfunctions and control group formed by noninfected cancer patients...
October 31, 2017: Blood Coagulation & Fibrinolysis: An International Journal in Haemostasis and Thrombosis
https://www.readbyqxmd.com/read/29081492/tissue-engineered-small-vessel-conduits-the-anti-thrombotic-effect-of-re-endothelialization-of-decellularized-baboon-arteries-a-preliminary-experimental-study
#3
Muriel Meiring, Mmakgabu Khemisi, Leana Laker, Pascal M Dohmen, Francis E Smit
BACKGROUND The use of decellularized biological scaffolds for the reconstruction of small-diameter vascular grafts remains a challenge in tissue engineering. Thrombogenicity is an important cause of obstruction in these vessels due to decellularization. Seeding of the decellularized vascular constructs with endothelial cells is therefore a prerequisite for the prevention of thrombosis. The aim of this study was to seed decellularized baboon arteries with endothelial cells and to compare the thrombogenicity to that of decellularized arteries after circulation of blood...
October 30, 2017: Medical Science Monitor Basic Research
https://www.readbyqxmd.com/read/29075447/stress-induced-changes-in-color-expression-mediated-by-iridophores-in-a-polymorphic-lizard
#4
Anna C Lewis, Katrina J Rankin, Andrew J Pask, Devi Stuart-Fox
Stress is an important potential factor mediating a broad range of cellular pathways, including those involved in condition-dependent (i.e., honest) color signal expression. However, the cellular mechanisms underlying the relationship between stress and color expression are largely unknown. We artificially elevated circulating corticosterone levels in male tawny dragon lizards, Ctenophorus decresii, to assess the effect of stress on the throat color signal. Corticosterone treatment increased luminance (paler throat coloration) and decreased the proportion of gray, thereby influencing the gray reticulations that produce unique patterning...
October 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/29075072/evaluation-of-coagulation-profile-in-children-with-type-1-diabetes-mellitus-using-rotational-thromboelastometry
#5
Cigdem Binay, Ayse Bozkurt Turhan, Enver Simsek, Ozcan Bor, Olga Meltem Akay
The prothrombotic state in type 1 diabetes mellitus (T1DM) has been reported as a plausible cause of vascular complications. Rotational thromboelastometry (ROTEM) assay enables the global assessment of coagulation status. This study aimed to assess hypercoagulability in children with T1DM using ROTEM. A total of 43 T1DM children (20 females and 23 males) aged 2-18 years and age- and sex-matched 30 healthy control subjects were enrolled in the study group. ROTEM assays [intrinsic TEM (INTEM) and extrinsic TEM (EXTEM)] were used to measure and analyze coagulation time (CT), clot formation time, maximum clot firmness (MCF)...
December 2017: Indian Journal of Hematology & Blood Transfusion
https://www.readbyqxmd.com/read/29063094/three-dimensional-porous-v2o5-hierarchical-spheres-as-a-battery-type-electrode-for-a-hybrid-supercapacitor-with-excellent-charge-storage-performance
#6
Yifu Zhang, Xuyang Jing, Qiushi Wang, Jiqi Zheng, Hanmei Jiang, Changgong Meng
Three-dimensional porous V2O5 hierarchical spheres composed of stacked platelets were fabricated by a facile, low-cost and template-free method. The synthetic route involved precipitation of precursor microspheres in aqueous solution at room temperature and subsequent calcination. Various techniques including XRD, FE-SEM, TEM, EDS, IR, Raman and nitrogen adsorption-desorption isotherms were used to reveal the composition, morphology and structure of the as-obtained porous V2O5 hierarchical spheres. The BET specific surface area of V2O5 hierarchical spheres measured 14 m(2)·g(-1) and their average pore size reached 18...
November 7, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/29061985/palaeobiology-of-red-and-white-blood-cell-like-structures-collagen-and-cholesterol-in-an-ichthyosaur-bone
#7
Chloé Plet, Kliti Grice, Anais Pagès, Michael Verrall, Marco J L Coolen, Wolfgang Ruebsam, William D A Rickard, Lorenz Schwark
Carbonate concretions are known to contain well-preserved fossils and soft tissues. Recently, biomolecules (e.g. cholesterol) and molecular fossils (biomarkers) were also discovered in a 380 million-year-old concretion, revealing their importance in exceptional preservation of biosignatures. Here, we used a range of microanalytical techniques, biomarkers and compound specific isotope analyses to report the presence of red and white blood cell-like structures as well as platelet-like structures, collagen and cholesterol in an ichthyosaur bone encapsulated in a carbonate concretion from the Early Jurassic (~182...
October 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29019369/in-situ-generation-of-layered-single-or-double-hydroxide-inorganic-platelets-lsh-and-ldh-assisted-by-bola-amphiphiles
#8
Arthur Langry, Joël Cellier, Horst Hintze-Bruening, Fabrice Leroux
A novel preparation route for layered hydroxide based hybrid phases has been investigated combining the polyol route with the in situ generation of inorganic platelets, in the presence of an amphiphilic polymer as well as bola-amphiphiles. The polyol route consists of hydrolysis in an alcoholic medium containing acetate metal cations as precursor(s), to yield an LDH Zn2Al cation composition or LSH-Zn (layered single hydroxide). A bola amphiphile is described as hydrophobic polymer segment-telechelic-chains terminated by two anionic hydrophilic end groups, using volatile ammonium cations as counter ions...
October 11, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28986333/protective-effect-of-danhong-injection-combined-with-naoxintong-capsule-on-cerebral-ischemia-reperfusion-injury-in-rats
#9
Jiayang Wan, Haofang Wan, Rongbin Yang, Haitong Wan, Jiehong Yang, Yu He, Huifen Zhou
ETHNOPHARMACOLOGICAL RELEVANCE: Danhong Injection (DHI) and Naoxintong Capsule (NXT) are renowned traditional Chinese medicine in China. The drug combination of DHI and NXT is frequently applied for the treatment of cardiovascular and cerebrovascular diseases in clinic. However, there had been no pharmacological experiment studies of interaction between DHI and NXT. Due to the drug interactions, exploring their interaction profile is of great importance. MATERIAL AND METHODS: In this study, focal cerebral I/R injury in adult male Sprague-Dawley rats were induced by transient middle cerebral artery occlusion (tMCAO) for 1h followed by reperfusion...
October 3, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28887963/facile-one-pot-green-synthesis-antibacterial-antifungal-antioxidant-and-antiplatelet-activities-of-lignin-capped-silver-nanoparticles-a-promising-therapeutic-agent
#10
M B Marulasiddeshwara, S S Dakshayani, M N Sharath Kumar, R Chethana, P Raghavendra Kumar, S Devaraja
The current work portrays the green synthesis of Lignin Capped Silver Nanoparticles (LCSN) and their antibacterial, antifungal, antioxidant and antiplatelet potential. The LCSN was synthesized in water using a carbohydrate based polymer 'lignin' as the reducing and capping agents. The peak at 406nm (λmax) in the UV-Vis., spectrum and EDX analysis confirmed 1.68% (w/w) of silver was found to be loaded on lignin. The characteristic sharp peaks appeared in the PXRD spectrum showed fcc crystalline structure LCSN...
December 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28833171/facile-synthesis-of-bioi-nanoparticles-at-room-temperature-and-evaluation-of-their-photoactivity-under-sunlight-irradiation
#11
Vahid Mahmoodi, Ali Ahmadpour, Tahereh Rohani Bastami, Mohammad Taghi Hamed Mousavian
In this study, highly photoactive BiOI nanoparticles (NPs) under sunlight irradiation were synthesized by a facile precipitation method using polyvinylpyrrolidone (PVP) at room temperature. The as-prepared catalysts were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), transition electron microscopy (TEM), energy-dispersive X-ray spectroscopy (EDX), Fourier transform infrared (FTIR) and UV-vis diffuse reflectance spectra (UV-vis DRS). The results of XRD showed that PVP did not have any significant effect on tetragonal crystalline structure of BiOI...
August 21, 2017: Photochemistry and Photobiology
https://www.readbyqxmd.com/read/28800610/anticoagulant-action-of-low-physiologic-and-high-albumin-levels-in-whole-blood
#12
Margret Paar, Christine Rossmann, Christoph Nusshold, Thomas Wagner, Axel Schlagenhauf, Bettina Leschnik, Karl Oettl, Martin Koestenberger, Gerhard Cvirn, Seth Hallström
Albumin is the most abundant plasma protein. Critical illness is often associated with altered, predominately decreased, serum albumin levels. This hypoalbuminaemia is usually corrected by administration of exogenous albumin. This study aimed to track the concentration-dependent influence of albumin on blood coagulation in vitro. Whole blood (WB) samples from 25 volunteers were prepared to contain low (19.3 ± 7.7 g/L), physiological (45.2 ± 7.8 g/L), and high (67.5 ± 18.1 g/L) levels of albumin. Haemostatic profiling was performed using a platelet function analyzer (PFA) 200, impedance aggregometry, a Cone and Platelet analyzer (CPA), calibrated automated thrombogram, and thrombelastometry (TEM)...
2017: PloS One
https://www.readbyqxmd.com/read/28780336/facile-one-pot-synthesis-of-cerium-oxide-sulfur-doped-graphitic-carbon-nitride-g-c3n4-as-efficient-nanophotocatalysts-under-visible-light-irradiation
#13
Milad Jourshabani, Zahra Shariatinia, Alireza Badiei
Porous CeO2/sulfur-doped g-C3N4 (CeO2/CNS) composites were synthesized by one-pot thermal condensation of thiourea and cerium nitrate as starting materials. The obtained CeO2(x)/CNS composites (x=8.4, 9.5 and 10.4wt%) with different CeO2 contents were characterized by the XRD, FT-IR, XPS, TEM, BET, DRS and PL analyses. The TEM images displayed a nonporous and platelet-like morphology for pure CNS but a nanoporous structure with numerous uniform pore sizes of ∼40nm for the CeO2(9.5)/CNS composite. The XRD phase structures and TEM morphologies confirmed that structural evolution trend and stacking degree of CNS were disrupted in precense of the CeO2 nanoparticles...
July 29, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28752997/synthesis-and-characterization-of-ultrathin-silver-sulfide-nanoplatelets
#14
Lenore Kubie, Laurie A King, Meghan E Kern, Joseph R Murphy, Subash Kattel, Qian Yang, Joshua T Stecher, William D Rice, Bruce A Parkinson
We report the synthesis of ultrathin silver sulfide (Ag2S) nanoplatelets (NPLs) synthesized via a one-pot method in ethylene glycol with 3-mercaptopropionic acid serving as both the sulfur precursor and the platelet ligand. The colloidally synthesized nanoplatelets are exceptionally thin, with a thickness of only 3.5 ± 0.2 Å and a 1S exciton Bohr diameter to confinement ratio of ∼12.6. The NPL growth is shown to be quantized by layer thickness using absorption and photoluminescence (PL) spectroscopy. Transmission electron microscopy, atomic force microscopy, and X-ray diffraction analyses of the NPLs show that they correspond to the (202) plane of the β-Ag2S structure...
August 22, 2017: ACS Nano
https://www.readbyqxmd.com/read/28702959/treatment-of-skin-defects-with-growth-factors-and-biodegradable-collagen-carrier-histological-evaluation-in-animal-model
#15
G B Menchini Fabris, P F Nocini, F Gelpi, J Lotti, V Favero, G Zanotti, A Jurlaro, I Rosskopf, T Lotti, A Barone, G Castegnaro, D De Santis
The aim of the present study is to evaluate the effects on skin regeneration of a new collagen matrix (CM-10826) when used in different combination with or without growth factors, using skin regeneration without membrane as control. An area of 10x15 cm on rabbit back was shaved and three circular wounds on test side were covered with a differently soaked membrane. The first wound was soaked with Epidermal Growth Factor (EGF, 26mg/130mL) (Test EGF), the second with Platelet-Derived Growth Factor (PDGF, 6mg/120mL) (Test PDGF) and the third with EGF (13mg/65mL) and PDGF (3mg/60mL) (Test EGF+PDGF)...
April 2017: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28559185/novel-dendritic-structure-of-alginate-hybrid-nanoparticles-for-effective-anti-viral-drug-delivery
#16
K S Joshy, Anne George, Jiya Jose, Nandakumar Kalarikkal, Laly A Pothen, Sabu Thomas
Lipid-polymer hybrid nanoparticles have recently gathered much attention as nanoplatforms for drug delivery applications due to their unique structural properties. In this study zidovudine (AZT) loaded hybrid nanoparticles of alginate (ALG) and stearic acid- poly ethylene glycol (SA-PEG) were synthesized. The structural characterization of drug loaded hybrid nanoparticles were studied using FT-IR spectroscopy, DLS and TEM analysis. These hybrid nanoparticles showed dendritic morphology and it can be used as an efficient carrier for zidovudine...
October 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28548818/pla-pbat-bionanocomposites-with-antimicrobial-natural-rosin-for-green-packaging
#17
Hesham Moustafa, Nadia El Kissi, Ahmed I Abou-Kandil, Mohamed S Abdel-Aziz, Alain Dufresne
The use of biodegradable polymers is of great importance nowadays in many applications. Some of the most commonly used biopolymers are polylactic acid (PLA) and poly(butylene adipate-co-terephthalate) (PBAT) due to their superior properties and availability. In this manuscript, we use a facile and green modification method of organoclay (OC) by antimicrobial natural rosin which is considered as a toxicity-free reinforcing material, thus keeping the green character of the material. It increases the interlayer spacing between the clay platelets...
June 2, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28532338/design-of-amphiphilic-pcl-peg-pcl-block-copolymers-as-vehicles-of-ginkgolide-b-and-their-brain-targeting-studies
#18
Xi-Qing Yan, Yong-Li Shi, Qing-Feng Jiang, Guan-Fang Ping, Zhi-Jian Deng
The amphiphilic PEG-b-PCL block copolymers were synthesized by ring-opening polymerization. The specific and selective antagonists of platelet activating factor, Ginkgolide B (GB), was successfully encapsulated in the synthesized PEG-PCL nanoparticles (NPs) with high Encapsulation Efficiency and Drug Loading. The synthesis of different PEG-PCL copolymers were confirmed with FTIR and (1)H NMR spectra. The morphology and particles size distribution of cargo-free PEG-PCL NPs were studied by transmission electron microscope (TEM) analysis and Malvern laser particle analyzer...
May 28, 2017: Journal of Biomaterials Science. Polymer Edition
https://www.readbyqxmd.com/read/28399723/germline-heterozygous-variants-in-genes-associated-with-familial-hemophagocytic-lymphohistiocytosis-as-a-cause-of-increased-bleeding
#19
Marcus Fager Ferrari, Eva Leinoe, Maria Rossing, Eva Norström, Karin Strandberg, Tobias Steen Sejersen, Klaus Qvortrup, Eva Zetterberg
Familial hemophagocytic lymphohistiocytosis (FHL) is caused by biallelic variants in genes regulating granule secretion in cytotoxic lymphocytes. In FHL3-5, the affected genes UNC13D, STX11 and STXBP2 have further been shown to regulate the secretion of platelet granules, giving rise to compromised platelet function. Therefore, we aimed to investigate platelet degranulation in patients heterozygous for variants in UNC13D, STX11 and STXBP2. During the work-up of patients referred to the Coagulation Unit, Skåne University Hospital, Malmö, Sweden and the Department of Hematology, Rigshospitalet, Copenhagen, Denmark due to bleeding tendencies, 12 patients harboring heterozygous variants in UNC13D, STX11 or STXBP2 were identified using targeted whole exome sequencing...
April 11, 2017: Platelets
https://www.readbyqxmd.com/read/28326239/nanostructured-carbon-materials-decorated-with-organophosphorus-moieties-synthesis-and-application
#20
Giacomo Biagiotti, Vittoria Langè, Cristina Ligi, Stefano Caporali, Maurizio Muniz-Miranda, Anna Flis, K Michał Pietrusiewicz, Giacomo Ghini, Alberto Brandi, Stefano Cicchi
A new synthetic approach for the production of carbon nanomaterials (CNM) decorated with organophosphorus moieties is presented. Three different triphenylphosphine oxide (TPPO) derivatives were used to decorate oxidized multiwalled carbon nanotubes (ox-MWCNTs) and graphene platelets (GPs). The TPPOs chosen bear functional groups able to react with the CNMs by Tour reaction (an amino group), nitrene cycloaddition (an azido group) or CuAAC reaction (one terminal C-C triple bond). All the adducts were characterized by FTIR, Raman spectroscopy, TEM, XPS, elemental analysis and ICP-AES...
2017: Beilstein Journal of Nanotechnology
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