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https://www.readbyqxmd.com/read/28634710/pharmacodynamic-and-pharmacokinetic-assessment-of-electronic-cigarettes-combustible-cigarettes-and-nicotine-gum-implications-for-abuse-liability
#1
Mitchell F Stiles, Leanne R Campbell, Donald W Graff, Bobbette A Jones, Reginald V Fant, Jack E Henningfield
RATIONALE: Electronic cigarettes (ECs) are becoming popular alternatives for smokers, but there has been limited study of their abuse liability. OBJECTIVES: The objective of this study was to evaluate the abuse liability of three Vuse Solo ECs, ranging from 14 to 36 mg in nicotine content, relative to high- and low-abuse liability comparator products (usual brand combustible cigarettes and nicotine gum, respectively) in a group of 45 EC-naïve smokers. METHODS: Enrolled subjects' ratings of subjective effects and nicotine uptake over 6 h were used to measure abuse liability and pharmacokinetics following in-clinic use of each EC...
June 20, 2017: Psychopharmacology
https://www.readbyqxmd.com/read/28634162/linking-the-content-to-demographic-reach-of-online-advertising-of-electronic-nicotine-delivery-systems
#2
David S Timberlake, Dmitriy Nikitin, Jennifer Garcia-Cano, Samantha Cino, Margarita Savkina, Cornelia Pechmann
INTRODUCTION: Recent studies have separately examined the content and demographic reach of the advertising of electronic nicotine delivery systems (ENDS). No study to our knowledge has linked the two in investigating whether racial/ethnic groups are differentially exposed to the comparative messages conveyed in online ENDS advertisements. METHODS: 932 unique ENDS advertisements (6311 total), which were posted on 3435 websites between December, 2009 and October, 2015, were categorized as either comparative or non-comparative with respect to the traditional cigarette...
June 20, 2017: Tobacco Control
https://www.readbyqxmd.com/read/28633573/should-we-encourage-smokers-with-severe-mental-illness-to-switch-to-electronic-cigarettes
#3
Ratika Sharma, Coral E Gartner, David J Castle, Colin P Mendelsohn
No abstract text is available yet for this article.
July 2017: Australian and New Zealand Journal of Psychiatry
https://www.readbyqxmd.com/read/28630116/attitudes-toward-tobacco-21-among-us-youth
#4
Hongying Dai
BACKGROUND: An important movement in reducing youth smoking is to restrict the supply of cigarettes to youth by raising the minimum age of sales to 21, termed Tobacco 21. This study examined attitudes toward Tobacco 21 among youth and their correlations with tobacco use. METHODS: Data from the 2015 National Youth Tobacco Survey (n = 17 092, the typical age of 11-18 years) were analyzed to examine the prevalence of support toward Tobacco 21 among youth. This study further assessed whether attitudes toward Tobacco 21 were associated with (1) intention to initiate cigarette smoking among never-smoking youth (n = 16 449); and (2) intention to quit tobacco use among current tobacco users (n = 2914)...
June 19, 2017: Pediatrics
https://www.readbyqxmd.com/read/28625973/prevalence-and-correlates-of-electronic-cigarette-use-among-canadian-students-cross-sectional-findings-from-the-2014-15-canadian-student-tobacco-alcohol-and-drugs-survey
#5
Annie Montreuil, Marjorie MacDonald, Mark Asbridge, T Cameron Wild, David Hammond, Steve Manske, Erin Rutherford
BACKGROUND: Over the past decade, youth tobacco use has declined, and electronic cigarettes (e-cigarettes) have entered the market. The aims of this study were to describe the prevalence of e-cigarette use among youth in Canada, by province, across sociodemographic variables and smoking-related correlates; and to examine associations among e-cigarette use, sociodemographic variables and smoking-related correlates, with adjustment for other factors. METHODS: The 2014/15 Canadian Student Tobacco, Alcohol and Drugs Survey, a biennial, school-based survey, was administered to students in grades 6-12 in all Canadian provinces...
June 14, 2017: CMAJ Open
https://www.readbyqxmd.com/read/28624763/electronic-cigarette-use-among-us-adults-in-the-population-assessment-of-tobacco-and-health-path-study-2013-2014
#6
Blair N Coleman, Brian Rostron, Sarah E Johnson, Bridget K Ambrose, Jennifer Pearson, Cassandra A Stanton, Baoguang Wang, Cristine Delnevo, Maansi Bansal-Travers, Heather L Kimmel, Maciej L Goniewicz, Raymond Niaura, David Abrams, Kevin P Conway, Nicolette Borek, Wilson M Compton, Andrew Hyland
BACKGROUND: Electronic cigarette (e-cigarette) use in the USA is increasing. As such, it is critical to understand who uses e-cigarettes, how e-cigarettes are used and what types of products are prevalent. This study assesses patterns of current e-cigarette use among daily and non-daily adult users in the 2013-2014 Population Assessment of Tobacco and Health (PATH) Study. METHODS: We examined the proportion of current adult e-cigarette users (n=3642) reporting infrequent use (use on 'some days' and use on 0-2 of the past 30 days), moderate use (use on 'some days' and use on >2 of the past 30 days) and daily use...
June 17, 2017: Tobacco Control
https://www.readbyqxmd.com/read/28624760/how-do-smoking-cessation-medicines-compare-with-respect-to-their-neuropsychiatric-safety-a-protocol-for-a-systematic-review-network-meta-analysis-and-cost-effectiveness-analysis
#7
Kyla H Thomas, Deborah Caldwell, Michael N Dalili, David Gunnell, Marcus R Munafò, Matt Stevenson, Nicky J Welton
INTRODUCTION: Cigarette smoking is one of the leading causes of early death in the UK and worldwide. Public health guidance recommends the use of varenicline, bupropion and nicotine replacement therapy (NRT) as smoking cessation aids in the UK. Additionally, the first electronic cigarette has been licensed for use as a smoking cessation medicine. However, there are ongoing concerns about the safety of these medicines. We present a protocol for a systematic review and network meta-analysis (NMA) to determine how these smoking cessation medicines compare to each other with respect to their neuropsychiatric safety in adult smokers...
June 17, 2017: BMJ Open
https://www.readbyqxmd.com/read/28621763/why-don-t-more-smokers-switch-to-using-e-cigarettes-the-views-of-confirmed-smokers
#8
Neil McKeganey, Tiffany Dickson
Whilst e-cigarettes have been characterised by Public Health England as being around 95% less harmful than combustible tobacco products, only a minority of current smokers (around 16% within the UK) are using these devices. In this paper we report the results of an online survey of 650 smokers in contact with a smokers' rights group in the UK. A total of 91% of the smokers surveyed were smoking on a daily basis. Fifty nine percent reported having used electronic nicotine delivery systems, the majority of whom reported having used e-cigarettes...
June 16, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28618425/electronic-cigarettes-in-germany-patterns-of-use-and-perceived-health-improvement
#9
Kirsten Lehmann, Silke Kuhn, Jens Reimer
AIMS: The aim of the study was to characterize e-cigarette users in terms of their consumption patterns, motives, and the perceived health benefits they experience from using e-cigarettes. DESIGN: The study was a cross-sectional online survey in 2015. A total of 3,320 German e-cigarette users were enrolled. A total of 91.5% were former tobacco smokers, 7.5% used both e-cigarettes and tobacco products, 1.0% were never-smokers. RESULTS: No differences were found between ex-smokers and dual users with regard to sociodemographic and smoking history (mean age 40...
June 16, 2017: European Addiction Research
https://www.readbyqxmd.com/read/28618214/how-to-stop-smoking
#10
Priyanga Jayakumar, Hema Madhuri Mekala, Rajashekar Reddy Yeruva, Steven Lippmann
Despite the known dangers of cigarette smoking, many smokers do not use effective means for cessation. Smoking-cessation guidelines recommend a variety of psychological and medicinal options that include nicotine-replacement products, pharmaceuticals, and electronic cigarettes. This article describes these smoking-cessation options and provides guidance for physicians.
June 8, 2017: Primary Care Companion to CNS Disorders
https://www.readbyqxmd.com/read/28617772/electronic-cigarettes-as-an-introductory-tobacco-product-among-eighth-and-11th-grade-tobacco-users-oregon-2015
#11
Jonas Z Hines, Steven C Fiala, Katrina Hedberg
During 2011-2015, increased electronic cigarette (e-cigarette) and hookah use offset declines in cigarette and other tobacco product use among youths (persons aged <18 years) (1). Limited information exists about which tobacco product introduced youths to tobacco product use. Patterns of first use of e-cigarettes among Oregon youths who were tobacco users were assessed in the Oregon Healthy Teens 2015 survey, a cross-sectional survey of eighth and 11th grade students in Oregon. Respondents were asked, "The very first time you used any tobacco or vaping product, which type of product did you use?" Among students who had ever used any tobacco product (ever users), e-cigarettes were the most common introductory tobacco product reported by both eighth (43...
June 16, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28617771/tobacco-use-among-middle-and-high-school-students-united-states-2011-2016
#12
Ahmed Jamal, Andrea Gentzke, S Sean Hu, Karen A Cullen, Benjamin J Apelberg, David M Homa, Brian A King
Tobacco use is the leading cause of preventable disease and death in the United States; nearly all tobacco use begins during youth and young adulthood (1,2). Among youths, use of tobacco products in any form is unsafe (1,3). CDC and the Food and Drug Administration (FDA) analyzed data from the 2011-2016 National Youth Tobacco Surveys (NYTS) to determine recent patterns of current (past 30-day) use of seven tobacco product types among U.S. middle (grades 6-8) and high (grades 9-12) school students. In 2016, 20...
June 16, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28607098/correlates-of-self-reported-exposure-to-advertising-of-tobacco-products-and-electronic-cigarettes-across-28-european-union-member-states
#13
Filippos T Filippidis, Anthony A Laverty, Esteve Fernandez, Ute Mons, Olena Tigova, Constantine I Vardavas
BACKGROUND: Despite advertising bans in most European Union (EU) member states, outlets for promotion of tobacco products and especially e-cigarettes still exist. This study aimed to assess the correlates of self-reported exposure to tobacco products and e-cigarettee advertising in the EU. METHODS: We analysed data from wave 82.4 of the Eurobarometer survey (November-December 2014), collected through interviews in 28 EU member states (n=27 801 aged ≥15 years) and data on bans of tobacco advertising extracted from the Tobacco Control Scale (TCS, 2013)...
June 12, 2017: Tobacco Control
https://www.readbyqxmd.com/read/28601841/electronic-cigarette-use-in-restaurants-and-workplaces-where-combustible-tobacco-smoking-is-not-allowed-an-internet-survey-in-japan
#14
Kosuke Kiyohara, Takahiro Tabuchi
BACKGROUND: The present study aimed to examine the experience of actual electronic cigarette (e-cigarette) use in smoke-free areas of restaurants and workplaces and to explore the determinants associated with such use among Japanese adults who reported any experience using e-cigarettes (e-cigarette ever-users). METHODS: An Internet-based self-reported questionnaire survey was conducted in 2015 on Japanese e-cigarette ever-users. The proportion of the respondents who had ever used or frequently used e-cigarettes in smoke-free restaurants and/or workplaces was calculated...
June 10, 2017: Tobacco Control
https://www.readbyqxmd.com/read/28596276/comparing-the-cytotoxicity-of-electronic-cigarette-fluids-aerosols-and-solvents
#15
Rachel Z Behar, Yuhuan Wang, Prue Talbot
BACKGROUND: As thousands of electronic cigarette (e-cigarette) refill fluids continue to be formulated and distributed, there is a growing need to understand the cytotoxicity of the flavouring chemicals and solvents used in these products to ensure they are safe. The purpose of this study was to compare the cytotoxicity of e-cigarette refill fluids/solvents and their corresponding aerosols using in vitro cultured cells. METHODS: E-cigarette refill fluids and do-it-yourself products were screened in liquid and aerosol form for cytotoxicity using the MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay...
June 8, 2017: Tobacco Control
https://www.readbyqxmd.com/read/28595990/-using-consumer-panels-in-public-health-observational-studies
#16
Nuria Matilla-Santander, Marcela Fu, Montse Ballbè, Cristina Lidón-Moyano, Juan Carlos Martín-Sánchez, Esteve Fernández, Jose M Martínez-Sánchez
Consumer panels are a market research method useful for gathering information about low-frequency or difficult-access customers. The objective of this field-note is to explain our experience using this method in a cross-sectional public health study on the use of electronic cigarettes. After taking into account other non-probabilistic sampling techniques to obtain a huge sample of electronic-cigarette users (n=600), in the end we decided to use consumer panels (recruiters) because of the relative short duration of the field work and the high representativeness of the sample...
June 5, 2017: Gaceta Sanitaria
https://www.readbyqxmd.com/read/28592404/alcohol-flavoured-tobacco-products
#17
Robert K Jackler, Callie K VanWinkle, Isabela M Bumanlag, Divya Ramamurthi
BACKGROUND: In 2009, the Food and Drug Administration (FDA) banned characterising flavours in cigarettes (except for menthol) due to their appeal to teen starter smokers. In August 2016, the agency deemed all tobacco products to be under its authority and a more comprehensive flavour ban is under consideration. OBJECTIVES: To determine the scope and scale of alcohol-flavoured tobacco products among cigars & cigarillos, hookahs and electronic cigarettes (e-cigarettes)...
June 7, 2017: Tobacco Control
https://www.readbyqxmd.com/read/28591788/electronic-cigarette-a-longitudinal-study-of-regular-vapers
#18
Jean-François Etter
Introduction.: It is unclear how vaping behaviour changes over time in regular vapers, and what occurs when vapers relapse to smoking or when they stop vaping. We assessed change in vaping and smoking behaviours over 12 months in regular vapers. Methods.: A longitudinal study of 3868 regular vapers enrolled on the Internet in 2012-2015 ("baseline"), followed after one (n=1631, 42%), three (n=1337, 35%), six (n=1148, 30%) and 12 months (n=893, 23%). Results...
June 7, 2017: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/28590444/consumers-preferences-for-electronic-nicotine-delivery-system-product-features-a-structured-content-analysis
#19
Christine E Kistler, Trisha M Crutchfield, Erin L Sutfin, Leah M Ranney, Micah L Berman, Gary A Zarkin, Adam O Goldstein
To inform potential governmental regulations, we aimed to develop a list of electronic nicotine delivery system (ENDS) product features important to U.S. consumers by age and gender. We employed qualitative data methods. Participants were eligible if they had used an ENDS at least once. Groups were selected by age and gender (young adult group aged 18-25, n = 11; middle-age group aged 26-64, n = 9; and women's group aged 26-64, n = 9). We conducted five individual older adult interviews (aged 68-80). Participants discussed important ENDS features...
June 7, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28576286/a-novel-hybrid-tobacco-product-that-delivers-a-tobacco-flavour-note-with-vapour-aerosol-part-1-product-operation-and-preliminary-aerosol-chemistry-assessment
#20
Simon Poynton, Joseph Sutton, Sharon Goodall, Jennifer Margham, Mark Forster, Ken Scott, Chuan Liu, Kevin McAdam, James Murphy, Christopher Proctor
Vapour products have demonstrated potential to be a lower-risk alternative to cigarettes. The present study describes a novel hybrid tobacco product that combines a warm aerosol stream generated by an electronic vaporisation mechanism with tobacco top flavour from cut tobacco. During operation, the aerosol stream released from the vapour cartomiser is passed through a bed of blended cut tobacco by the puffing flow, elevating the tobacco temperature and eluting volatile tobacco flavour components. A preliminary but comprehensive analysis of the aerosol composition of the hybrid tobacco product found that emissions were dominated by the control vapour formulation...
May 30, 2017: Food and Chemical Toxicology
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