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https://www.readbyqxmd.com/read/28081200/fitter-women-did-not-have-attenuated-hemodynamic-responses-to-psychological-stress-compared-with-age-matched-women-with-lower-levels-of-fitness
#1
Sisitha U Jayasinghe, Susan J Torres, Mais Hussein, Steve F Fraser, Gavin W Lambert, Anne I Turner
According to the 'cross stressor adaptation hypothesis', regular exercise acts as a buffer against the detrimental effects of stress. Nevertheless, evidence that higher levels of cardiorespiratory fitness moderate hemodynamic responses to acute psychological stress is inconclusive, especially in women. Women aged 30-50 years (in the mid-follicular phase of the menstrual cycle) with higher (n = 17) and lower (n = 17) levels of fitness were subjected to a Trier Social Stress Test (TSST). Continuous, non-invasive measurements were made of beat-to-beat, systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), heart rate (HR), stroke volume (SV), cardiac output (CO), left ventricular ejection time (LVET), maximum slope, pulse interval (PI) and total peripheral resistance (TPR)...
2017: PloS One
https://www.readbyqxmd.com/read/28079402/sexual-dysfunction-in-premenopausal-women-could-be-related-to-hormonal-profile
#2
Fabiene Bernardes Castro Vale, Bruna Barbosa Coimbra, Gerson Pereira Lopes, Selmo Geber
Female sexual dysfunction (FSD) is a public health problem that affects women's quality of life. Although the relationship between some hormones and the FSD has been described, it is not well established for all hormones. Therefore, the aim of our study was to evaluate the association between hormonal dysfunction and sexual dysfunction in premenopausal women. We performed a cross-sectional study with 60 patients with regular menstrual cycles, with age ranging from 18 to 44 years, with previous diagnosis of FSD...
January 12, 2017: Gynecological Endocrinology
https://www.readbyqxmd.com/read/28077439/the-functional-expression-of-transient-receptor-potential-channels-in-the-mouse-endometrium
#3
Katrien De Clercq, Charlotte Van den Eynde, Aurélie Hennes, Rieta Van Bree, Thomas Voets, Joris Vriens
STUDY QUESTION: Does mouse endometrial epithelial cells and stromal cells have a similar transient receptor potential (TRP)-channel expression profile and to that found in the human endometrium? SUMMARY ANSWER: Mouse endometrial epithelial and stromal cells have a distinct TRP channel expression profile analogous to what has been found in human endometrium, and hence suggests the mouse a good model to investigate the role of TRP channels in reproduction. WHAT IS KNOWN ALREADY: An optimal intercellular communication between epithelial and stromal endometrial cells is crucial for successful reproduction...
January 6, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28076829/comparing-the-effect-of-aromatase-inhibitor-letrozole-cabergoline-dostinex-and-letrozole-alone-on-uterine-myoma-regression-a-randomized-clinical-trial
#4
M Sayyah-Melli, M Mobasseri, P M Gharabaghi, E Ouladsahebmadarek, V Rahmani
OBJECTIVE: To evaluate the effect of letrozole in combination with cabergoline and letrozole alone on regression of symptomatic uterine myomas in women of reproductive age. DESIGN: Randomized controlled clinical trial. SETTING: University hospital. PATIENTS: Ninety-one women of reproductive age were enrolled in the study and 88 women were eligible. Eight participants were excluded from the study. INTERVENTIONS: Eighty women of reproductive age with symptomatic myomas >4cm were evaluated in two groups...
December 23, 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28069897/impact-of-estrogen-receptor-%C3%AE-gene-and-oxytocin-receptor-gene-polymorphisms-on-female-sexuality
#5
Anastasia K Armeni, Konstantinos Assimakopoulos, Dimitra J Marioli, Vasiliki Koika, Eftychia Michailidou, Niki Mourtzi, Gregoris Iconomou, Neoklis A Georgopoulos
Over the past decades, research attention has increasingly been paid to the neurobiological component of sexual behaviour. The aim of the present study was to investigate the correlation of estrogen receptor α (ERα) gene polymorphism (rs2234693-PvuII) (T→C substitution) and oxytocin receptor gene polymorphism (rs53576) (G→A substitution) with sexuality parameters of young, healthy women. One hundred thirty-three Greek heterosexual women, students in higher education institutions, 20-25 years of age, sexually active, with normal menstrual cycles (28-35 days), were recruited in the study...
January 9, 2017: Endocrine Connections
https://www.readbyqxmd.com/read/28069449/a-model-of-ovulatory-regulation-examining-the-effects-of-insulin-mediated-testosterone-production-on-ovulatory-function
#6
Erica J Graham, James F Selgrade
Polycystic ovary syndrome (PCOS), a common cause of infertility in women, is often accompanied by abnormal reproductive and metabolic hormone levels. Specifically, androgens such as testosterone are elevated in many PCOS women, and the syndrome itself is frequently associated with insulin resistance, which leads to hyperinsulinemia, i.e., elevated insulin. Although the precise role of insulin in ovulatory function is unclear, its role in ovulatory dysfunction is often linked to the effects of increased ovarian androgen production...
January 6, 2017: Journal of Theoretical Biology
https://www.readbyqxmd.com/read/28065695/perfusion-of-the-uterine-junctional-zone-in-nulliparous-and-primiparous-women-assessed-by-dce-mri-as-a-function-of-menstrual-cycle-and-hormonal-contraception
#7
L J Meylaerts, L Wijnen, M Bazot, M Grieten, W Ombelet, M Vandersteen
PURPOSE: To evaluate the perfusion parameters of inner and outer myometrium in healthy nulliparous and primiparous women who are and who are not currently using hormonal contraceptives by means of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI). MATERIAL AND METHODS: We performed pelvic 1.5T DCE-MRI on 98 women: 18 nulliparous non-users, 30 nulliparous users, 12 primiparous non-users and 38 primiparous users of hormonal contraception (mean age respectively 26...
January 6, 2017: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/28065424/associations-between-urinary-biomarkers-of-polycyclic-aromatic-hydrocarbon-exposure-and-reproductive-function-during-menstrual-cycles-in-women
#8
Ulrike Luderer, Fletcher Christensen, Wesley O Johnson, Jianwen She, Ho Sai Simon Ip, Junqiang Zhou, Josephine Alvaran, Edward F Krieg, James S Kesner
Essentially all women are exposed to polycyclic aromatic hydrocarbons (PAHs), formed during incomplete combustion of organic materials, including fossil fuels, wood, foods, and tobacco. PAHs are ovarian toxicants in rodents, and cigarette smoking is associated with reproductive abnormalities in women. Biomonitoring of hydroxylated PAH (OH-PAH) metabolites in urine provides an integrated measure of exposure to PAHs via multiple routes and has been used to characterize exposure to PAHs in humans. We hypothesized that concentrations of OH-PAHs in urine are associated with reproductive function in women...
January 5, 2017: Environment International
https://www.readbyqxmd.com/read/28064085/cortisol-awakening-response-is-blunted-and-pain-perception-is-increased-during-menses-in-cyclic-women
#9
Tuba Ozgocer, Cihat Ucar, Sedat Yildiz
BACKGROUND AND AIMS: The incidence of menstrual symptoms is reported to be as high as 90% in cyclic women. These symptoms, including anxiety and pain, might be associated with cortisol, as its receptors are widely distributed in the brain areas associated with behavior. Therefore, the current study aimed to assess the cortisol awakening response (CAR) throughout the menstrual cycle and correlate it with pain perception and trait anxiety. MATERIALS AND METHODS: CAR was assessed by measuring salivary cortisol at 0, 15, 30, and 60min following awakening in the same women (n=59, age 22...
December 21, 2016: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28061371/low-level-arsenic-exposure-via-drinking-water-consumption-and-female-fecundity-a-preliminary-investigation
#10
Michele L Susko, Michael S Bloom, Iulia A Neamtiu, Allison A Appleton, Simona Surdu, Cristian Pop, Edward F Fitzgerald, Doru Anastasiu, Eugen S Gurzau
High level arsenic exposure is associated with reproductive toxicity in experimental and observational studies; however, few data exist to assess risks at low levels. Even less data are available to evaluate the impact of low level arsenic exposure on human fecundity. Our aim in this pilot study was a preliminary evaluation of associations between low level drinking water arsenic contamination and female fecundity. This retrospective study was conducted among women previously recruited to a hospital-based case-control study of spontaneous pregnancy loss in Timiṣ County, Romania...
January 3, 2017: Environmental Research
https://www.readbyqxmd.com/read/28060011/topical-tenofovir-protects-against-vaginal-shiv-infection-in-macaques-co-infected-with-chlamydia-trachomatis-and-trichomonas-vaginalis
#11
Natalia Makarova, Tara Henning, Andrew Taylor, Chuong Dinh, Jonathan Lipscomb, Rachael Aubert, Debra Hanson, Christi Phillips, John Papp, James Mitchell, Janet Mcnicholl, Gerardo J Garcia-Lerma, Walid Heneine, Ellen Kersh, Charles Dobard
BACKGROUND: Chlamydia trachomatis (CT) and Trichomonas vaginalis (TV), two prevalent sexual transmitted infections, are known to increase HIV risk in women and could potentially diminish pre-exposure prophylaxis (PrEP) efficacy, particularly for topical interventions that rely on local protection. We investigated in macaques whether co-infection with CT/TV reduces protection by vaginal TFV gel. METHODS: Vaginal TFV gel dosing previously shown to provide 100% or 74% protection when applied either 30 minutes or 3 days before SHIV challenge was assessed in pigtailed macaques co-infected with CT/TV and challenged twice-weekly with SHIV162p3 for up to 10 weeks (2 menstrual cycles)...
January 4, 2017: AIDS
https://www.readbyqxmd.com/read/28054823/estradiol-related-variations-in-top-down-and-bottom-up-processes-of-cerebral-lateralization
#12
Sophie Hodgetts, Susanne Weis, Markus Hausmann
OBJECTIVE: Natural fluctuations of sex hormones have been shown to modulate cerebral lateralization in dichotic listening tasks. Two recent studies presented contradictory notions regarding the mechanism of this effect. Specifically, whereas Hjelmervik et al. (2012) suggested that estradiol affects lateralization by enhancing top-down processes, such as cognitive control, Hodgetts, Weis, and Hausmann, (2015) suggested that the effect was attributable to estradiol-related variations in bottom-up aspects of lateralization...
January 5, 2017: Neuropsychology
https://www.readbyqxmd.com/read/28053281/recurrent-psychotic-episodes-with-a-near-monthly-cycle
#13
K I Che
A 12-year-old girl presented to the mental health service for an abrupt onset of mental changes characterised by hearing voices and being paranoid. She appeared preoccupied and her mood was labile. There was no family history of mental illness, and no organic causes were identified. These symptoms subsided spontaneously in a week. However, she experienced 3 other similar psychotic episodes afterwards which happened in a near-monthly cycle. Her level of functioning was normal between these episodes. Throughout the course of the illness, it was noted that these mental state changes might be related to the menstrual cycle...
December 2016: East Asian Archives of Psychiatry: Official Journal of the Hong Kong College of Psychiatrists
https://www.readbyqxmd.com/read/28042403/comparison-of-the-effect-of-stretching-exercises-and-mefenamic-acid-on-the-reduction-of-pain-and-menstruation-characteristics-in-primary-dysmenorrhea-a-randomized-clinical-trial
#14
Narges Motahari-Tabari, Marjan Ahmad Shirvani, Abbas Alipour
OBJECTIVES: Dysmenorrhea is a common gynecologic disorder. Although non-steroidal anti-inflammatory drugs are commonly used, due to their side effects and lack of response in some individuals, other approaches such as exercise have been considered. This study compared the effect of stretching exercises and mefenamic acid on the reduction of pain and menstruation characteristics in primary dysmenorrhea. METHODS: In this randomized clinical trial, 122 female students with moderate to severe dysmenorrhea were assessed and were placed in either the exercise or mefenamic acid group...
January 2017: Oman Medical Journal
https://www.readbyqxmd.com/read/28041951/the-role-of-sex-hormones-and-steroid-receptors-on-female-reproductive-cancers
#15
REVIEW
Luiz Gustavo de Almeida Chuffa, Luiz Antonio Lupi-Júnior, Aline Balandis Costa, João Paulo de Arruda Amorim, Fábio Rodrigues Ferreira Seiva
Sex steroids have been widely described to be associated with a number of human diseases, including hormone-dependent tumors. Several studies have been concerned about the factors regulating the availability of sex steroids and its importance in the pathophysiological aspects of the reproductive cancers in women. In premenopausal women, large fluctuations in the concentration of circulating estradiol (E2) and progesterone (P4) orchestrate many events across the menstrual cycle. After menopause, the levels of circulating E2 and P4 decline but remain at high concentration in the peripheral tissues...
December 29, 2016: Steroids
https://www.readbyqxmd.com/read/28041829/cryopreserved-embryo-transfer-adjacent-or-non-adjacent-to-failed-fresh-long-gnrh-agonist-protocol-ivf-cycle
#16
Alexander Volodarsky-Perel, Talia Eldar-Geva, Hananel E G Holzer, Oshrat Schonberger, Orna Reichman, Michael Gal
The optimal time to perform cryopreserved embryo transfer (CET) after a failed oocyte retrieval-embryo transfer (OR-ET) cycle is unknown. Similar clinical pregnancy rates were recently reported in immediate and delayed CET, performed after failed fresh OR-ET, in cycles with the gonadotrophin-releasing hormone (GnRH) antagonist protocol. This study compared outcomes of CET performed adjacently (<50 days, n = 67) and non-adjacently (≥50 to 120 days, n = 62) to the last OR-day of cycles with the GnRH agonist down-regulation protocol...
December 16, 2016: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/28034986/influence-of-sexual-hormones-on-neural-orofacial-perception
#17
Bruna Alves, Flavia Ibuki, Alyne Simões Gonçalves, Manoel Jacobsen Teixeira, Silvia Regina Dowgan Tesseroli De Siqueira
OBJECTIVE  : To investigate the trigeminal somatosensory (thermal, pain, tactile, vibratory, and electric), gustative (salty, bitter, sweet, sour), and olfactory thresholds in healthy women during the menstrual cycle and investigate any association with estradiol and progesterone levels in saliva. METHODS : We examined/tested 39 women between age 19 and 47 years and with regular menstrual cycles and no comorbidities. All women were informed about the purposes of the study, and only those who signed the informed consent were included...
December 29, 2016: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28034579/a-randomized-clinical-trial-of-a-culturally-responsive-intervention-for-african-american-women-with-asthma
#18
Minal R Patel, Peter X K Song, Georgiana Sanders, Belinda Nelson, Elena Kaltsas, Lara J Thomas, Mary R Janevic, Kausar Hafeez, Wen Wang, Margaret Wilkin, Timothy R Johnson, Randall W Brown
BACKGROUND: Few interventions have focused on the difficulties that African American women face when managing asthma. OBJECTIVE: To evaluate a telephone-based self-regulation intervention that emphasized African American women's management of asthma in a series of 6 sessions. METHODS: A total of 422 African American women with persistent asthma were randomly assigned to either an intervention or control group receiving usual care. Behavioral factors, symptoms and asthma control, asthma-related quality of life, and health care use at baseline and 2 years after baseline were assessed...
December 26, 2016: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/28013526/myeloperoxidase-in-blood-neutrophils-during-normal-and-abnormal-menstrual-cycles-in-women-of-reproductive-age
#19
T Shibata, J Sakamoto, Y Osaka, N Neyatani, S Fujita, Y Oka, H Takagi, H Mori, H Fujita, Y Tanaka, T Sasagawa
INTRODUCTION: We previously reported that granulocyte colony-stimulating factor (G-CSF) plays a critical role in ovulation, suggesting that neutrophils may maintain ovulation. We assessed myeloperoxidase (MPO), a major and specific enzyme of neutrophils, in women with abnormal and normal menstrual cycles to clarify the relationship between MPO and ovulation. METHODS: We analyzed MPO activity in blood neutrophils of women with abnormal menstrual cycles (indicative of anovulation, n = 12) and age- and body mass index-matched normal menstrual cycles (indicative of ovulation, n = 24) using two parameters as a marker of MPO, Neut X and mean peroxidase index (MPXI)...
December 25, 2016: International Journal of Laboratory Hematology
https://www.readbyqxmd.com/read/28012351/the-association-between-mental-health-problems-and-menstrual-cycle-irregularity-among-adolescent-korean-girls
#20
Mi Yu, Kyungdo Han, Ga Eun Nam
BACKGROUND: Menstrual cycle irregularity is common among adolescents and can induce mental health problems such as stress, depression, and suicidal ideation. We examined the association between mental health problems and menstrual cycle irregularity among adolescent Korean girls. METHODS: This population-based cross-sectional study was on 808 female adolescents (12-18 years of age) participating in the 2010-2012 Korean National Health and Nutrition Examination Survey...
November 30, 2016: Journal of Affective Disorders
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