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https://www.readbyqxmd.com/read/28724173/a-comparative-study-between-myo-inositol-and-metformin-in-the-treatment-of-insulin-resistant-women
#1
K Nas, L Tűű
OBJECTIVE: Insulin resistance (IR) is a common disorder, which can impair female fertility and is characterized by phenotypic heterogeneity. Life-style treatment and insulin sensitizers are commonly used in the management of women with IR and consequent hyperinsulinemia, in order to restore the normal endocrinological and clinical parameters. Metformin (MET) is considered one of the first approaches to this pathology but new evidences are showing promising results using myo-inositol (MYO) in the management of this pathology...
June 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28723963/impact-of-thyroid-function-abnormalities-on-reproductive-hormones-during-menstrual-cycle-in-premenopausal-hiv-infected-females-at-nauth-nnewi-nigeria
#2
Nkiruka Rose Ukibe, Solomon Nwabueze Ukibe, Obiageli Fidelia Emelumadu, Chinedum Charles Onyenekwe, Joseph Eberendu Ahaneku, Anthony Osita Igwegbe, Ifeoma Nwamaka Monago, Amobi Linus Ilika
BACKGROUND: This was a prospective study designed to evaluate the impact of thyroid function abnormalities on reproductive hormones during menstrual cycle in HIV infected females at Nnamdi Azikiwe University Teaching Hospital Nnewi, South-East Nigeria. METHODS: The study randomly recruited 35 Symptomatic HIV infected females and 35 Symptomatic HIV infected females on antiretroviral therapy (HAART) for not less than six weeks from an HIV clinic and 40 apparently heathy control females among the hospital staff of NAUTH Nnewi...
2017: PloS One
https://www.readbyqxmd.com/read/28723842/reduced-neuromuscular-performance-in-amenorrheic-elite-endurance-athletes
#3
Åsa B Tornberg, Anna Melin, Fiona Manderson Koivula, Anders Johansson, Sven Skouby, Jens Faber, Anders Sjödin
INTRODUCTION: Secondary functional hypothalamic amenorrhea (SFHA) is common among female athletes, especially in weight-sensitive sports. The aim of this study was to investigate the link between SFHA and neuromuscular performance in elite endurance athletes. METHODS: Sixteen eumenorrheic (EUM) and 14 SFHA athletes from national teams and competitive clubs participated. Methods included gynecological examination; body composition (DXA);; resting metabolic rate and work efficiency; exercise capacity; knee muscular strength (KMS) and knee muscular endurance (KME); reaction time (RT); blood sampling performed on the 3rd-5th day of the menstrual cycle, and 7-day assessment of energy availability...
July 19, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28717621/effects-of-the-menstrual-cycle-on-lower-limb-biomechanics-neuromuscular-control-and-anterior-cruciate-ligament-injury-risk-a-systematic-review
#4
REVIEW
Vivek Balachandar, Jan-Luigi Marciniak, Owen Wall, Chandrika Balachandar
OBJECTIVE: Anterior cruciate ligament (ACL) injury has a devastating impact on physical and psychological disability. Rates of ACL rupture are significantly greater in females than males during the same sports. Hormonal mechanisms have been proposed but are complex and poorly understood. This systematic review evaluates the effects of menstrual cycle on: 1) lower-limb biomechanics, 2) neuromuscular control, and 3) ACL injury risk. METHODS: The MEDLINE, CINAHL, SPORTSDiscus, Web of Science, and Google Scholar databases were searched from inception to August 2016 for studies investigating the effects of the menstrual cycle on lower-limb biomechanics, neuromuscular control, and ACL injury risk in females...
January 2017: Muscles, Ligaments and Tendons Journal
https://www.readbyqxmd.com/read/28713996/downregulation-of-aqp2-in-the-anterior-vaginal-wall-is-associated-with-the-pathogenesis-of-female-stress-urinary-incontinence
#5
Zujuan Zhang, Pan Xu, Zhenwei Xie, Fengxian Shen, Ning Chen, Liming Yu, Ronghuan He
The pathogenesis of stress urinary incontinence (SUI) is unclear. Aquaporins (AQPs) are a family of transmembrane proteins that transport water and small solutes, including glycerol, across cell membranes. AQPs have been demonstrated to serve a role in skin hydration, cellular proliferation, migration, immunity, wound healing and vascular remodeling in multiple organs. Furthermore, studies have confirmed that abnormal synthesis and degradation of collagens in extracellular matrix (ECM) remodeling contributes to SUI, by altering normal tissue architecture and mechanical properties...
July 15, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28712426/negative-affect-is-unrelated-to-fluctuations-in-hormone-levels-across-the-menstrual-cycle-evidence-from-a-multisite-observational-study-across-two-successive-cycles
#6
Michael P Hengartner, Tillmann H C Kruger, Kirsten Geraedts, Enrico Tronci, Toni Mancini, Fabian Ille, Marcel Egli, Susanna Röblitz, Rainald Ehrig, Lanja Saleh, Katharina Spanaus, Cordula Schippert, Yuanyuan Zhang, Brigitte Leeners
BACKGROUND: Female sex hormones may play a crucial role in the occurrence of cycle-related mood disorders. However, the literature is inconsistent and methodologically stringent observational studies on the relationship between sex hormones and negative affect are lacking. METHODS: In this longitudinal multisite study from Hannover, Germany, and Zurich, Switzerland, we examined oestrogen, progesterone, luteinizing hormone (LH), follicle-stimulating hormone (FSH), and testosterone serum levels in association with negative affect as measured with the Positive and Negative Affect Schedule (PANAS)...
August 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/28712125/oral-contraceptive-pill-alters-acute-dietary-protein-induced-thermogenesis-in-young-women
#7
Maharani Retna Duhita, Yves Schutz, Jean-Pierre Montani, Abdul G Dulloo, Jennifer L Miles-Chan
OBJECTIVE: There is much interest in the role of dietary protein for weight control. However, there remains a need to characterize individual determinants of the thermogenic effects of protein. This study aimed to investigate the influence of menstrual cycle phase and the combined, monophasic oral contraceptive pill on the thermogenic response to a standardized high-protein (HP) versus normal-protein (NP) meal. METHODS: Following an overnight fast, resting energy expenditure (EE) was measured in 16 healthy young women (8 taking and 8 not taking the pill) and 8 men for 30 minutes pre ingestion and 3 hours post ingestion of a NP (11%) or HP (24%) meal...
July 16, 2017: Obesity
https://www.readbyqxmd.com/read/28706612/polymorphisms-in-the-estrogen-receptor-beta-gene-and-the-risk-of-unexplained-recurrent-spontaneous-abortion
#8
Marzieh Mahdavipour, Saeed Zarei, Ramina Fatemi, Haleh Edalatkhah, Hamed Heidari-Vala, Mahmood Jeddi-Tehrani, Farah Idali
BACKGROUND: Recurrent Spontaneous Abortion (RSA) is caused by multiple genetic and non-genetic factors. Around 50% of the RSA cases have no known etiology and are considered as Unexplained RSA (URSA). Estrogens, via binding to their receptors, play an important role in female reproduction. This study aimed to investigate whether single nucleotide polymorphisms (SNPs; +1082G/A, +1730G/A and rs1256030 C/T) in the estrogen receptor beta (ESR2) gene are associated with susceptibility to URSA in a population of Iranian women...
July 2017: Avicenna Journal of Medical Biotechnology
https://www.readbyqxmd.com/read/28706369/improving-the-knowledge-and-attitude-on-standard-days-method-of-family-planning-through-a-promotional-program-among-indian-postgraduate-students
#9
Philby Babu Menachery, Judith Angelitta Noronha, Sweety Fernanades
INTRODUCTION: The 'Standard Days Method' is a fertility awareness-based method of family planning that identifies day 8 through day 19 of the menstrual cycle as fertile days during which a woman is likely to conceive with unprotected intercourse. OBJECTIVE: The study was aimed to determine the effectiveness of a promotional program on the 'Standard Days Method' in terms of improving the knowledge scores and attitude scores. DESIGN: A pre-experimental one-group pretest-posttest research design was adopted...
August 2017: Journal of Obstetrics and Gynaecology of India
https://www.readbyqxmd.com/read/28700680/the-role-of-treatment-timing-and-mode-of-stimulation-in-the-treatment-of-primary-dysmenorrhea-with-acupuncture-an-exploratory-randomised-controlled-trial
#10
Mike Armour, Hannah G Dahlen, Xiaoshu Zhu, Cindy Farquhar, Caroline A Smith
OBJECTIVES: We examined the effect of changing treatment timing and the use of manual, electro acupuncture on the symptoms of primary dysmenorrhea. METHODS: A randomised controlled trial was performed with four arms, low frequency manual acupuncture (LF-MA), high frequency manual acupuncture (HF-MA), low frequency electro acupuncture (LF-EA) and high frequency electro acupuncture (HF-EA). A manualised trial protocol was used to allow differentiation and individualized treatment over three months...
2017: PloS One
https://www.readbyqxmd.com/read/28694347/menstrual-hygiene-management-among-bangladeshi-adolescent-schoolgirls-and-risk-factors-affecting-school-absence-results-from-a-cross-sectional-survey
#11
Mahbub-Ul Alam, Stephen P Luby, Amal K Halder, Khairul Islam, Aftab Opel, Abul K Shoab, Probir K Ghosh, Mahbubur Rahman, Therese Mahon, Leanne Unicomb
BACKGROUND: Many adolescent girls in low-income and middle-income countries lack appropriate facilities and support in school to manage menstruation. Little research has been conducted on how menstruation affects school absence. This study examines the association of menstrual hygiene management knowledge, facilities and practice with absence from school during menstruation among Bangladeshi schoolgirls. METHODS: We conducted a nationally representative, cross-sectional study in Bangladeshi schools from March to June 2013 among girls 11 to 17 years old who reached menarche...
July 9, 2017: BMJ Open
https://www.readbyqxmd.com/read/28694156/sex-and-menstrual-cycle-influences-on-three-aspects-of-attention
#12
Belinda Pletzer, Ti-Anni Harris, Tuulia Ortner
Sex differences and menstrual cycle influences have been investigated in a variety of cognitive abilities, but results regarding attention are comparably sparse. In the present study, 35 men and 32 naturally cycling women completed three attention tasks, which are commonly used in neuropsychological assessment situations. All participants completed two sessions, which were time-locked to the follicular (low progesterone) and luteal cycle phase (high progesterone) in women. The results reveal higher operation speed during sustained attention in men, but no sex differences in selected and divided attention...
July 8, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28693005/george-papanicolaou-s-efforts-to-develop-novel-cytologic-methods-for-the-early-diagnosis-of-endometrial-carcinoma
#13
R Marshall Austin
Toward the end of his career, Dr. George Papanicolaou became interested in human endometrial explants placed into tissue culture. The initial focus of his studies was on phagocytic cells emanating from endometrial explants and their role in cleansing the uterine cavity after each menstrual cycle and in sterilizing the uterine cavity in the face of infection. Papanicolaou also observed that growth rates of explanted normal and pathologic endometrial tissues differed considerably. Explants of endometrial malignancies exhibited not only increased growth rates but also visible proliferation of cells with readily identifiable cytologic features of malignancy...
July 11, 2017: Acta Cytologica
https://www.readbyqxmd.com/read/28692631/increased-protein-requirements-in-female-athletes-after-variable-intensity-exercise
#14
Denise J Wooding, Jeff E Packer, Hiroyuki Kato, Daniel W D West, Glenda Courtney-Martin, Paul B Pencharz, Daniel R Moore
PURPOSE: Protein requirements are primarily studied in the context of resistance or endurance exercise with little research devoted to variable-intensity intermittent exercise characteristic of many team sports. Further, female populations are underrepresented in dietary sports science studies. We aimed to determine a dietary protein requirement in active females performing variable-intensity intermittent exercise using the indicator amino acid oxidation (IAAO) method. We hypothesized that these requirements would be greater than current IAAO-derived estimates in non-active adult males...
July 7, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28691671/bilateral-primary-ovarian-non-hodgkin-s-lymphoma-and-fertility-preservation-5-year-follow-up
#15
C Grigoriadis, A Tympa, A Chasiakou, S Baka, D Botsis, D Hassiakos
AIM: Primary ovarian non-Hodgkin's lymphoma is a very rare disease. Median age at diagnosis is estimated at 42 years, something that leads to fertility preservation issues in many cases. This was a case report study, presenting a rare case of bilateral primary ovarian non-Hodgkin's lymphoma. CASE REPORT: A 38-year old nulliparous woman, underwent exploratory laparotomy because of bilateral ovarian masses. Left salpingooophorectomy, partial omentectomy and excision of an ovarian mass of the right ovary was performed...
March 2017: Il Giornale di Chirurgia
https://www.readbyqxmd.com/read/28686000/effect-of-near-infrared-rays-on-female-menstrual-pain-in-korea
#16
Jin-Min Lee, Kye-Ha Kim
Most Korean women who experience menstrual pain have reported taking pain medicine and making use of complementary alternative therapies. However, because some interventions may cause side effects, more effective pain-relieving measures need to be identified. This study using a non-equivalent group design, evaluated the effects of near-infrared rays on dysmenorrhea among Korean women. The experimental group wore a near-infrared ray abdominal belt for the duration of one menstrual cycle until the end of the menstrual period, while the control group used hot packs...
July 7, 2017: Nursing & Health Sciences
https://www.readbyqxmd.com/read/28685514/association-between-body-weight-changes-and-menstrual-irregularity-the-korea-national-health-and-nutrition-examination-survey-2010-to-2012
#17
Kyung Min Ko, Kyungdo Han, Youn Jee Chung, Kun Ho Yoon, Yong Gyu Park, Seung Hwan Lee
BACKGROUND: Menstrual irregularity is an indicator of endocrine disorders and reproductive health status. It is associated with various diseases and medical conditions, including obesity and underweight. We aimed to assess the association between body weight changes and menstrual irregularity in Korean women. METHODS: A total of 4,621 women 19 to 54 years of age who participated in the 2010 to 2012 Korea National Health and Nutrition Examination Survey were included in this study...
June 2017: Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28685096/oral-contraceptives-cause-evolutionarily-novel-increases-in-hormone-exposure-a-risk-factor-for-breast-cancer
#18
Jennie L Lovett, Margo A Chima, Juliana K Wexler, Kendall J Arslanian, Andrea B Friedman, Chantal B Yousif, Beverly I Strassmann
Background and objectives: In the evolutionary past, women spent most of their reproductive lives either pregnant or in lactational amenorrhea, and rarely menstruated. The current pattern of frequent menses, and the associated increase in endogenous hormonal exposure, has been implicated in the current breast cancer epidemic. It is not known, however, whether oral contraceptives further increase, or actually decrease, hormonal exposure over one menstrual cycle. Here, we examined variation in hormonal exposure across seven oral contraceptive (OC) formulations, and produced the first quantitative comparison of exogenous versus endogenous hormone exposure...
2017: Evolution, Medicine, and Public Health
https://www.readbyqxmd.com/read/28684053/three-step-method-for-menstrual-and-oral-contraceptive-cycle-verification
#19
Mia A Schaumberg, David G Jenkins, Xanne A K Janse de Jonge, Lynne M Emmerton, Tina L Skinner
OBJECTIVES: Fluctuating endogenous and exogenous ovarian hormones may influence exercise parameters; yet control and verification of ovarian hormone status is rarely reported and limits current exercise science and sports medicine research. The purpose of this study was to determine the effectiveness of an individualised three-step method in identifying the mid-luteal or high hormone phase in endogenous and exogenous hormone cycles in recreationally-active women and determine hormone and demographic characteristics associated with unsuccessful classification...
August 26, 2016: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/28683601/dysregulation-of-gda-expression-in-endometrium-of-women-with-endometriosis-implication-for-endometrial-receptivity
#20
Riccardo Focarelli, Alice Luddi, Vincenzo De Leo, Angela Capaldo, Anita Stendardi, Valentina Pavone, Linda Benincasa, Giuseppe Belmonte, Felice Petraglia, Paola Piomboni
Glycodelin-A (GdA) has been proposed to represent a potential biomarker of endometrial function, but little is known about its expression during the different phases of the menstrual cycle and under pathological conditions. In the light of its potential importance also in embryo implantation, we aimed to evaluate the expression profile of GdA as well as the presence of different glycosylated glycoforms and the immunolocalization in endometrial tissue from women with endometriosis and in women with proven fertility, at different times during the menstrual cycle...
January 1, 2017: Reproductive Sciences
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