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https://www.readbyqxmd.com/read/28937041/evaluation-of-circulating-endometrial-cells-as-a-biomarker-for-endometriosis
#1
Ying Chen, Hong-Lan Zhu, Zhe-Wen Tang, Kuang Hong Neoh, Dong-Fang Ouyang, Heng Cui, Hong-Yan Cheng, Rui-Qiong Ma, Xue Ye, Ray Ps Han, Xiao-Hong Chang
BACKGROUND: Circulating endometrial cells (CECs) have been reported to be present in the peripheral blood of women with endometriosis (EM), providing clear and specific evidence of the presence of ectopic lesions. In this study, we established a method with a high detection rate of CECs, assessed the diagnostic value of CECs for EM and compared with serum CA125, and proposed a hypothesis for the pathogenesis of EM from the new perspective of CECs. METHODS: The participants were enrolled prospectively from October 2015 to July 2016...
October 5, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28936905/microwave-diathermy-and-transcutaneous-electrical-nerve-stimulation-effects-in-primary-dysmenorrhea-clinical-trial-protocol
#2
Aline Fernanda Perez Machado, Monica Rodrigues Perracini, Ariane da Cruz Saraiva de Morais, Bruna Oliveira da Silva, Patricia Driusso, Richard Eloin Liebano
The aim of this study will be to analyze the effects of microwave diathermy (MWD) and transcutaneous electrical nerve stimulation (TENS) on primary dysmenorrhea. Eighty eight women, age range 18-44 years, with no previous pregnancy, no practice physical activities, a BMI of ≤29.9 kg/m(2), a regular menstrual cycle and a diagnosis of primary dysmenorrhea, with menstrual pain ranging from mild to severe, will be selected. The participants will be randomized into four groups: MWD and TENS, MWD and placebo TENS, placebo MWD and TENS, and placebo MWD and placebo TENS...
September 22, 2017: Pain Management
https://www.readbyqxmd.com/read/28932611/chronic-pelvic-pain-and-infertility-resulting-from-unrecognized-retained-laminaria
#3
Wesley Nilsson, Sasha Mikhael, Jennifer Kaplan
BACKGROUND: In 2013, the abortion rate in the United States was found to be 200 abortions per 1,000 live births. Of these, the CDC estimates that nearly 49% were performed using unsafe measures. Even when these procedures are safely performed, patients are at risk for immediate or delayed complications. In second-trimester terminations, mechanical dilation with an osmotic dilator is common to allow for delivery of the fetus. The Japanese seaweed Laminaria japonica is used to achieve this purpose...
2017: Case Reports in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28931859/a-longitudinal-analysis-of-the-vaginal-microbiota-and-vaginal-immune-mediators-in-women-from-sub-saharan-africa
#4
Vicky Jespers, Jordan Kyongo, Sarah Joseph, Liselotte Hardy, Piet Cools, Tania Crucitti, Mary Mwaura, Gilles Ndayisaba, Sinead Delany-Moretlwe, Jozefien Buyze, Guido Vanham, Janneke H H M van de Wijgert
In cross-sectional studies increased vaginal bacterial diversity has been associated with vaginal inflammation which can be detrimental for health. We describe longitudinal changes at 5 visits over 8 weeks in vaginal microbiota and immune mediators in African women. Women (N = 40) with a normal Nugent score at all visits had a stable lactobacilli dominated microbiota with prevailing Lactobacillus iners. Presence of prostate-specific antigen (proxy for recent sex) and being amenorrhoeic (due to progestin-injectable use), but not recent vaginal cleansing, were significantly associated with microbiota diversity and inflammation (controlled for menstrual cycle and other confounders)...
September 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28930874/the-effectiveness-of-fish-oil-supplementation-in-attenuating-exercise-induced-muscle-damage-in-females-during-mid-follicular-and-mid-luteal-menstrual-phases
#5
Sarah K McKinley-Barnard, Thomas L Andre, Josh J Gann, Paul S Hwang, Darryn S Willoughby
The purpose of this study was to determine if the differences in estrogen levels during the female menstrual cycle and fish oil supplementation would attenuate eccentric exercise-induced muscle damage (EIMD) and delayed onset muscle soreness (DOMS). In a double-blind fashion, 22 physically-active females (20.9 ± 1.4 years, 63.5 ± 9.0 kg, 165.2 ± 7.5 cm) were randomly assigned to ingest either 6 grams of fish oil (n = 11) or placebo (n = 11) daily for 21 days. Participants underwent an eccentric exercise bout of the knee extensors on two occasions during the mid-follicular (MF) and mid-luteal (ML) phases of the 28-day menstrual cycle...
September 11, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28930603/centchroman-a-safe-reversible-postcoital-contraceptive-with-curative-and-prophylactic-activity-in-many-disorders
#6
Ved P Kamboj, Suprabhat Ray, Nitya Anand
Centchroman (INN: Ormeloxifene), a reversible post-coital/weekly oral contraceptive (half-life of about 168 hours), designed and developed at CDRI, Lucknow is the only non-steroidal oral contraceptive in clinical use in the world today. Synthesized in 1967 and completing pre-clinical and clinical studies in 1989, this drug was approved for marketing in 1991, social marketing in 1995 and NFPW in April 2016. It acts by preventing implantation of blastocyst in endometrium. It is the only contraceptive which neither suppresses ovulation nor interferes with the hypothalamic-pituitary-ovarian axis...
January 1, 2018: Frontiers in Bioscience (Elite Edition)
https://www.readbyqxmd.com/read/28930223/successful-pregnancy-after-treatment-with-chinese-herbal-medicine-in-a-43-year-old-woman-with-diminished-ovarian-reserve-and-multiple-uterus-fibrosis-a-case-report
#7
Benqi Teng, Jie Peng, Madeleine Ong, Xianqin Qu
OBJECTIVE: To highlight a natural approach to coexisting oligomenorrhea, subfertility, luteal phase insufficiency and multiple fibroids cohesively when in vitro fertilisation (IVF) has failed. CASE PRESENTATION: A 43-year-old woman with diminished ovarian reserve and multiple uterine fibroids had previously been advised to discontinue IVF treatment. According to Chinese Medicine diagnosis, herbal formulae were prescribed for improving age-related ovarian insufficiency as well as to control the growth of fibroids...
February 9, 2017: Medicines (Basel, Switzerland)
https://www.readbyqxmd.com/read/28929436/endogenous-sex-hormone-exposure-and-repetitive-element-dna-methylation-in-healthy-postmenopausal-women
#8
Devon J Boyne, Christine M Friedenreich, John B McIntyre, Frank Z Stanczyk, Kerry S Courneya, Will D King
PURPOSE: Epigenetic mechanisms may help to explain the complex and heterogeneous relation between sex hormones and cancer. Few studies have investigated the effects of sex hormones on epigenetic markers related to cancer risk such as levels of methylation within repetitive DNA elements. Our objective was to describe the association between endogenous sex hormone exposure and levels of LINE-1 and Alu methylation in healthy postmenopausal women. METHODS: We nested a cross-sectional study within the Alberta Physical Activity and Breast Cancer Prevention Trial (2003-2006)...
September 19, 2017: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/28928434/the-effect-of-frozen-thawed-embryo-transfer-performed-concurrently-with-hysteroscopy-on-the-reproductive-outcomes-during-assisted-reproductive-treatments
#9
Xiuxian Zhu, Hongjuan Ye, Yonglun Fu
The uterine environment is vital to the successful conception; recently, hysteroscopy was used to remove uterine anomalies in patients undergoing assisted reproductive treatments in combination with a "freeze-all" strategy. However, the rapid recurrence of uterine anomalies impose a negative impact on pregnancy. A possible way to avoid this issue is to implement frozen-thawed embryo transfer (FET) as soon as possible. Thus, we sought to investigate the impact of performing FET concurrently with hysteroscopy in the same mense on the pregnancy outcome...
September 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28927742/the-effect-of-sex-and-menstrual-phase-on-memory-formation-during-nap
#10
Sara C Mednick, Negin Sattari, Elizabeth A McDevitt, Dagmara Panas, Mohammad Niknazar, Maryam Ahmadi, Mohsen Naji, Fiona Baker
Memory formation can be influenced by sleep and sex hormones in both men and women, and by the menstrual cycle in women. Though many studies have shown that sleep benefits the consolidation of memories, it is not clear whether this effect differs between men and women in general or according to menstrual phase in women. The present study investigated the effect of sex and menstrual cycle on memory consolidation of face-name associations (FNA) following a daytime nap. Recognition memory was tested using a face-name paired associates task with a polysomnographic nap between morning and evening testing...
September 16, 2017: Neurobiology of Learning and Memory
https://www.readbyqxmd.com/read/28925275/-catamenial-pneumothorax-case-reports-and-literature-review
#11
E Voláková, V Kolek, J Kufa, J Zatloukal, J Chudáček, M Szkorupa, R Pilka
AIM: Catamenial pneumothorax is menstrual cycle dependent and represents the most common form of thoracic endometriosis syndrome. Recurrences are very common even after surgical resection. DESIGN: Case reports and literature overview. SETTING: Department of Respiratory Medicine, Department of Surgery I, Department of Obstetrics and Gynecology, University Hospital, Palacky University, Olomouc. CASE REPORT: Two cases of catamenial pneumothorax are presented with repeated recurrences of right-sided pneumothorax even after surgical treatment...
2017: Ceská Gynekologie
https://www.readbyqxmd.com/read/28923287/aberrant-expression-of-epithelial-leucine-rich-repeat-containing-g-protein-coupled-receptor-5-positive-cells-in-the-eutopic-endometrium-in-endometriosis-and-implications-in-deep-infiltrating-endometriosis
#12
Júlia Vallvé-Juanico, Elena Suárez-Salvador, Josep Castellví, Agustín Ballesteros, Hugh S Taylor, Antonio Gil-Moreno, Xavier Santamaria
OBJECTIVE: To characterize leucine-rich repeat containing G protein-coupled receptor 5-positive (LGR5(+)) cells from the endometrium of women with endometriosis. DESIGN: Prospective experimental study. SETTING: University hospital/fertility clinic. PATIENT(S): Twenty-seven women with endometriosis who underwent surgery and 12 healthy egg donors, together comprising 39 endometrial samples. INTERVENTION(S): Obtaining of uterine aspirates by using a Cornier Pipelle...
September 15, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28917614/age-and-fecundability-in-a-north-american-preconception-cohort-study
#13
Amelia K Wesselink, Kenneth J Rothman, Elizabeth E Hatch, Ellen M Mikkelsen, Henrik T Sørensen, Lauren A Wise
BACKGROUND: There is a well-documented decline in fertility treatment success with increasing female age; however, there are few preconception cohort studies examining female age and natural fertility. In addition, data on male age and fertility is inconsistent. Given the increasing number of couples attempting conception at older ages, a more detailed characterization of age-related fecundability in the general population is of great clinical utility. OBJECTIVE: To examine the association between female and male age with fecundability...
September 13, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28917360/a-randomized-controlled-clinical-trial-evaluating-quality-of-life-when-using-a-simple-acupressure-protocol-in-women-with-primary-dysmenorrhea
#14
Fatemeh Bazarganipour, Seyed-Abdolvahab Taghavi, Helen Allan, Nazafarin Hosseini, Ahmad Khosravi, Rahimeh Asadi, Shohreh Salari, Raziyeh Dehghani, Zahra Jamshidi, Marziyeh Rezaei, Mansoreh Saberian, Fatemeh Javedan, Zahra Salari, Fahimeh Miri
OBJECTIVE: To evaluate a simple acupressure protocol in LIV3 and LI4 acupoints in women with primary dysmenorrhea. METHODS: This paper reports a randomized, single blinded clinical trial. 90 young women with dysmenorrhea were recruited to three groups to receive 20min acupressure every day in either LIV3 or LI4, or placebo points. Acupressure was timed five days before menstruation for three successive menstrual cycles. On menstruation, each participant completed the Wong Baker faces pain scale, and the quality of life short form -12 (QOL SF-12)...
October 2017: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/28915617/predictive-factors-of-pathologic-complete-response-in-her2-positive-and-axillary-lymph-node-positive-breast-cancer-after-neoadjuvant-paclitaxel-carboplatin-plus-with-trastuzumab
#15
Jinhua Ding, Yinlong Yang, Li Jiang, Weizhu Wu, Zhiming Shao
OBJECTIVE: This study was performed to investigate the proportion as well as the predictive factors of pathologic complete response in HER2-positive and axillary lymph node positive breast cancer after neoadjuvant paclitaxel, carboplatin plus with trastuzumab (PCH). RESULTS: The pCR rate in the breast, axilla and both was 44.3% (39/88), 47.7% (42/88) and 34.1% (30/88), respectively. Patients with and without pCR were similar in term of age, BMI, menstrual status, family history, treatment cycles and tumor characteristics (laterality and size of tumor)...
August 22, 2017: Oncotarget
https://www.readbyqxmd.com/read/28913369/changes-in-the-width-of-the-tibiofibular-syndesmosis-related-to-lower-extremity-joint-dynamics-and-neuromuscular-coordination-on-drop-landing-during-the-menstrual-cycle
#16
Michie Okazaki, Masaaki Kaneko, Yukisato Ishida, Norio Murase, Toshihito Katsumura
BACKGROUND: Many injuries of the lower extremities, especially the knee and ankle, occur during sports activity, and the incidence rate is higher in women than in men. HYPOTHESIS: The hypothesis was that phases of the menstrual cycle affect the width of the tibiofibular syndesmosis during drop landing in healthy young women and that such changes at the tibiofibular joint also affect the dynamics and neuromuscular coordination of the lower extremities. STUDY DESIGN: Descriptive laboratory study...
September 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/28911927/dynamic-expression-of-pgrmc1-and-serbp1-in-human-endometrium-an-implication-in-the-human-decidualization-process
#17
Stefania Salsano, Alicia Quiñonero, Silvia Pérez, Tamara Garrido Gómez, Carlos Simón, Francisco Dominguez
OBJECTIVE: To characterize PGRMC1 and SERBP1 in human endometrium and to investigate the putative role of PGRMC1 in endometrial decidualization. DESIGN: The PGRMC1 and SERBP1 expression in human endometrium was determined throughout the menstrual cycle. We analyzed the colocalization of PGRMC1 and SERBP1. Then, endometrial stromal cells (ESCs) were isolated to investigate the functional effect of PGRMC1 overexpression on decidualization. SETTING: IVI clinic...
September 11, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28911214/growth-regulation-by-estrogen-in-breast-cancer-1-greb1-is-a-novel-progesterone-responsive-gene-required-for-human-endometrial-stromal-decidualization
#18
Alison J Camden, Maria M Szwarc, Sangappa B Chadchan, Francesco J DeMayo, Bert W O'Malley, John P Lydon, Ramakrishna Kommagani
STUDY QUESTION: Is Growth Regulation by Estrogen in Breast Cancer 1 (GREB1) required for progesterone-driven endometrial stromal cell decidualization? SUMMARY ANSWER: GREB1 is a novel progesterone-responsive gene required for progesterone-driven human endometrial stromal cell (HESC) decidualization. WHAT IS KNOWN ALREADY: Successful establishment of pregnancy requires HESCs to transform from fibroblastic to epithelioid cells in a process called decidualization...
September 1, 2017: Molecular Human Reproduction
https://www.readbyqxmd.com/read/28911135/is-it-me-or-my-hormones-neuroendocrine-activation-profiles-to-visual-food-stimuli-across-the-menstrual-cycle
#19
Yardena Arnoni-Bauer, Atira Bick, Noa Raz, Tal Imbar, Shoshana Amos, Orly Agmon, Limor Marko, Netta Levin, Ram Weiss
Context: Homeostatic energy balance is controlled via the hypothalamus, whereas regions controlling reward and cognitive decision-making are critical for hedonic eating. Eating varies across the menstrual cycle peaking at the midluteal phase. Objective: To test responses of females with regular cycles during midfollicular and midluteal phase and of users of monophasic oral contraception pills (OCPs) to visual food cues. Design: Participants performed a functional magnetic resonance imaging while exposed to visual food cues in four time points: fasting and fed conditions in midfollicular and midluteal phases...
September 1, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28906053/the-effects-of-menstrual-cycle-phase-on-the-incidence-of-plateau-at-v%C3%AB-o2max-and-associated-cardiorespiratory-dynamics
#20
Dan Gordon, Adrian Scruton, Richard Barnes, James Baker, Luciano Prado, Viviane Merzbach
The purpose of this study was to examine the effect of menstrual cycle phase on maximal oxygen uptake (V˙O2max) and associated cardiodynamic responses. A total of 16 active females volunteered of which n = 10 formed the non-oral contraceptive pill group (n-OCP), displaying a regular menstrual cycle of 28·4 ± 2·2 days (age 20·6 ± 1·6 years, height 169·9 ± 6·4 cm, mass 68·7 ± 7·9 kg) and n = 6 formed the oral contraceptive pill group (OCP) (monophasic pill) (age 21·7 years ± 2·16, height 168·1 cm ± 6·8 cm, mass 61·6 ± 6·8 kg)...
September 14, 2017: Clinical Physiology and Functional Imaging
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