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https://www.readbyqxmd.com/read/29147898/-don-t-mind-the-gap-reflections-on-improvement-science-as-a-paradigm
#1
Trenholme Junghans
Responding to this issue's invitation to bring new disciplinary insights to the field of improvement science, this article takes as its starting point one of the field's guiding metaphors: the imperative to "mind the gap". Drawing on insights from anthropology, history, and philosophy, the article reflects on the origins and implications of this metaphoric imperative, and suggests some ways in which it might be in tension with the means and ends of improvement. If the industrial origins of improvement science in the twentieth century inform a metaphor of gaps, chasms, and spaces of misalignment as invariably imperfect and potentially dangerous, and therefore requiring bridging or closure, other currents that feed the discipline of improvement science suggest the potential value and uses of spaces of openness and ambiguity...
November 17, 2017: Health Care Analysis: HCA: Journal of Health Philosophy and Policy
https://www.readbyqxmd.com/read/29147119/psychosocial-factors-predicting-length-of-hospitalization-in-elderly-individuals-with-diabetes-in-selected-hospitals-of-isfahan-university-of-medical-sciences-isfahan-iran-in-2015
#2
Omeleila Baharlooei, Mousa Alavi, Marzieh Adelmehraban
BACKGROUND: Currently, researchers seek to identify factors related to length of hospital stay in elderly in order to reduce burden on the health system. The importance of either physiological or psychological factors in determining health outcomes has been well stablished; however, the possible contribution of psychosocial factors particularly in elderly patients with diabetes is also of special importance. This study aimed to know what psychosocial variables predicts length of hospital stay in elderly patients with diabetes...
May 2017: ARYA Atherosclerosis
https://www.readbyqxmd.com/read/29146909/interference-like-patterns-of-static-magnetic-fields-imprinted-into-polymer-nanoparticle-composites
#3
Zhijie Yang, Jingjing Wei, Konrad Giżynski, Myung-Geun Song, Bartosz A Grzybowski
Interference of waves is important and used in many areas of science and technology but does not extend to static magnetic fields which lack the wave structure. On the other hand, magnetic fields can be spatially modulated using microstructured materials comprising magnetic and non-magnetic domains. Here, we show that when such spatial modulation is coupled to the dynamics of magnetic particles, it can give rise to interference-like patterns. These patterns are imprinted into thin polymer films by overlaying "stamps" presenting periodic arrays of magnetic and nonmagnetic regions...
November 16, 2017: Nature Communications
https://www.readbyqxmd.com/read/29143223/accelerating-and-strengthening-native-american-health-research-through-a-collaborative-nih-initiative
#4
Aria Davis Crump, Kathy Etz, Judith A Arroyo, Nanci Hemberger, Shobha Srinivasan
This paper is intended to provide an overview of the considerations that informed the development of a National Institutes of Health funding opportunity to promote health and prevent disease in Native Americans, including American Indian, Alaska Native, and Native Hawaiian communities. NIH Institute staff thoughtfully considered epidemiologic research findings and feedback from constituents regarding the need for more published research overall and stronger prevention efforts to address persistent health concerns affecting many Native communities...
November 16, 2017: Prevention Science: the Official Journal of the Society for Prevention Research
https://www.readbyqxmd.com/read/29141197/medical-abortion-reversal-science-and-politics-meet
#5
Khadijah Z Bhatti, Antoinette T Nguyen, Gretchen S Stuart
Medical abortion is a safe, effective, and acceptable option for patients seeking an early non-surgical abortion. In 2014, medical abortion accounted for nearly one-third (31%) of all abortions performed in the United States. State-level attempts to restrict reproductive and sexual health have recently included bills that require physicians to inform women that a medical abortion is reversible. In this commentary, we will review the history, current evidence-based regimen, and regulation of medical abortion...
November 12, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29140916/gender-disparities-in-medical-student-research-awards-a-thirteen-year-study-from-the-yale-school-of-medicine
#6
Joseph T King, Nancy R Angoff, John N Forrest, Amy C Justice
PURPOSE: Instruction in research conduct is currently required, and many U.S. medical schools require students to complete a research project. Each year all Yale School of Medicine (YSM) graduating students submit a research thesis, and ~5% are awarded highest honors. Gender disparities exist in areas related to physician research productivity, including academic rank, research funding, and publications. The authors asked whether gender disparities exist for medical student research. METHOD: The authors conducted a retrospective review of 1,120 theses submitted by graduating medical students from 2003-2015 at YSM and collected data on gender, mentoring, research type, sponsoring department, and other characteristics...
November 14, 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/29140766/the-rise-of-alternative-bread-leavening-technologies-in-the-nineteenth-century
#7
Carolyn Ann Cobbold
This article reveals how nineteenth-century chemists and health reformers tried to eradicate the use of yeast in bread, claiming they had devised healthier and more sanitary ways to raise bread. It describes the alternative technological solutions to baking bread, investigating factors that influenced their development and adaptation in the marketplace. A lack of scientific and cultural consensus surrounding yeast, what it was and what it did, fermented during this period. The conflict over yeast helped create a heterogeneous industrialization of the baking industry, changing processes and ingredients and creating new forms of bakery products...
November 15, 2017: Annals of Science
https://www.readbyqxmd.com/read/29140435/hmdb-4-0-the-human-metabolome-database-for-2018
#8
David S Wishart, Yannick Djoumbou Feunang, Ana Marcu, An Chi Guo, Kevin Liang, Rosa Vázquez-Fresno, Tanvir Sajed, Daniel Johnson, Carin Li, Naama Karu, Zinat Sayeeda, Elvis Lo, Nazanin Assempour, Mark Berjanskii, Sandeep Singhal, David Arndt, Yonjie Liang, Hasan Badran, Jason Grant, Arnau Serra-Cayuela, Yifeng Liu, Rupa Mandal, Vanessa Neveu, Allison Pon, Craig Knox, Michael Wilson, Claudine Manach, Augustin Scalbert
The Human Metabolome Database or HMDB (www.hmdb.ca) is a web-enabled metabolomic database containing comprehensive information about human metabolites along with their biological roles, physiological concentrations, disease associations, chemical reactions, metabolic pathways, and reference spectra. First described in 2007, the HMDB is now considered the standard metabolomic resource for human metabolic studies. Over the past decade the HMDB has continued to grow and evolve in response to emerging needs for metabolomics researchers and continuing changes in web standards...
November 11, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/29139032/radium-biophysics-and-radiobiology-tracing-the-history-of-radiobiology-in-twentieth-century-china
#9
Christine Yi Lai Luk
Radiobiology assesses the biological hazards of exposure to radioactive substances and nuclear radiation. This article explores the history of radiobiology in twentieth-century China by examining the overlapping of radium research and biophysics, from roughly the 1920s Nationalist period to the 1960s Communist period; from the foreign purchase of radium by the Rockefeller Foundation's China Medical Board during the Republican era, to the institutional establishment of radiobiology as a subset of biophysics in the People's Republic...
November 2, 2017: History and Philosophy of the Life Sciences
https://www.readbyqxmd.com/read/29136189/serum-omega-3-fatty-acids-and-treatment-outcomes-among-women-undergoing-assisted-reproduction
#10
Y-H Chiu, A E Karmon, A J Gaskins, M Arvizu, P L Williams, I Souter, B R Rueda, R Hause, J E Chavarro
STUDY QUESTION: Are serum polyunsaturated fatty acids (PUFA) concentrations, including omega-3 (ω3-PUFA) and omega-6 (ω6-PUFA), related to ART outcomes? SUMMARY ANSWER: Serum levels of long-chain ω3-PUFA were positively associated with probability of live birth among women undergoing ART. WHAT IS KNOWN ALREADY: Intake of ω3-PUFA improves oocyte and embryo quality in animal and human studies. However, a recent cohort study found no relation between circulating ω3-PUFA levels and pregnancy rates after ART...
November 10, 2017: Human Reproduction
https://www.readbyqxmd.com/read/29133451/chance-necessity-and-the-origins-of-life-a-physical-sciences-perspective
#11
Robert M Hazen
Earth's 4.5-billion-year history has witnessed a complex sequence of high-probability chemical and physical processes, as well as 'frozen accidents'. Most models of life's origins similarly invoke a sequence of chemical reactions and molecular self-assemblies in which both necessity and chance play important roles. Recent research adds two important insights into this discussion. First, in the context of chemical reactions, chance versus necessity is an inherently false dichotomy-a range of probabilities exists for many natural events...
December 28, 2017: Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences
https://www.readbyqxmd.com/read/29132835/a-history-that-goes-hand-in-hand-reflections-on-the-development-of-health-economics-and-the-role-played-by-social-science-medicine-1967-2017
#12
Joanna Coast
No abstract text is available yet for this article.
October 31, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/29127930/indoor-air-quality-of-environments-used-for-physical-exercise-and-sports-practice-systematic-review
#13
REVIEW
Alexandro Andrade, Fábio Hech Dominski
BACKGROUND: Systematic reviews have the potential to contribute substantially to environmental health and risk assessment. OBJECTIVE: This study aimed to investigate indoor air quality of environments used for physical exercise and sports practice through a systematic review. METHODS: The systematic review followed the PRISMA guidelines and was recorded in the PROSPERO registry (CRD42016036057). The search was performed using the SciELO, Science Direct, Scopus, LILACS, MEDLINE via PubMed, and SPORTDiscus databases, from their inception through April 2017...
November 8, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/29127067/understanding-the-structural-drivers-governing-glass-water-interactions-in-borosilicate-based-model-bioactive-glasses
#14
Nicholas Stone-Weiss, Eric M Pierce, Randall E Youngman, Ozgur Gulbiten, Nicholas J Smith, Jincheng Du, Ashutosh Goel
The past decade has witnessed a significant upsurge in the development of borate and borosilicate based resorbable bioactive glasses owing to their faster degradation rate in comparison to their silicate counterparts. However, due to our lack of understanding about the fundamental science governing the aqueous corrosion of these glasses, most of the borate/borosilicate based bioactive glasses reported in the literature have been designed by "trial-and-error" approach. With an ever-increasing demand for their application in treating a broad spectrum of non-skeletal health problems, it is becoming increasingly difficult to design advanced glass formulations using the same conventional approach...
November 7, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/29123356/translational-research-in-oncology-implications-for-palliative-care
#15
Arunangshu Ghoshal
The label "translational research" (TR) has become ever more popular in the biomedical domain in recent years. It is usually presented as an attempt to bridge a supposed gap between knowledge produced at the laboratory bench and its use at the clinical bedside. This is claimed to help society harvest the benefits of its investments in scientific research. The past decade has witnessed a remarkable acceleration in the pace of translational cancer medicine - genome sequencing of various human cancers has been broadly deployed in drug discovery programs, diagnostic tests have been developed to predict molecularly targeted anticancer agents, advent of cancer immunotherapies, an enhanced appreciation of the complex interactions that exist between tumor cells and their microenvironment have revolutionized the management of cancers...
October 2017: Indian Journal of Palliative Care
https://www.readbyqxmd.com/read/29119410/africanizing-science-in-post-colonial-kenya-long-term-field-research-in-the-amboseli-ecosystem-1963-1989
#16
Amanda E Lewis
Following Kenya's independence in 1963, scientists converged on an ecologically sensitive area in southern Kenya on the northern slope of Mt. Kilimanjaro called Amboseli. This region is the homeland of the Ilkisongo Maasai who grazed this ecosystem along with the wildlife of interest to the scientists. Biologists saw opportunities to study this complex community, an environment rich in biological diversity. The Amboseli landscape proved to be fertile ground for testing new methods and lines of inquiry in the biological sciences that were generalizable and important for shaping natural resource management policies in Kenya...
November 8, 2017: Journal of the History of Biology
https://www.readbyqxmd.com/read/29118870/risk-factors-for-gastroesophageal-reflux-disease-in-saudi-arabia
#17
Ali Mesfer Alkhathami, Abdulrahman Ahmad Alzahrani, Mohammed Abdullah Alzhrani, Obaidallah Buraykan Alsuwat, Mohammad Eid Mahmoud Mahfouz
Background: Gastroesophageal reflux disease (GERD) is one of the most prevalent gastrointestinal tract diseases worldwide. GERD has an effect on the patients' quality of life as well as the health care system that can be prevented by identifying its risk factors among the population. Hence, we applied this study to assess the GERD's risk factors in Saudi Arabia. Methods: A cross-sectional study was designed to assess the GERD's risk factors among the community of Saudi Arabia...
October 2017: Gastroenterology Research
https://www.readbyqxmd.com/read/29118523/three-cases-of-hair-loss-analyzed-by-the-point-of-view-of-the-analytical-psychology
#18
Ademir Carvalho Leite Júnior, Tatiele Katzer, Denise Gimenez Ramos
Psychotrichology is the science, which covers the psychosomatics applied to hair problems, i.e., body-psyche phenomena involving scalp and hair disorders. The approaches involving psychotricology are varied and may include psychiatric,[1] psychoanalytical,[23] and those involving knowledge related to analytical psychology.[4] An analysis from the analytical psychology point of view, a theory developed by the physician Carl Gustav Jung, favors a symbolic view to the disease, providing it attributions and meanings that go beyond those related to physical body signs and symptoms only...
October 2017: International Journal of Trichology
https://www.readbyqxmd.com/read/29118406/single-cell-co-expression-subnetwork-analysis
#19
Thomas E Bartlett, Sören Müller, Aaron Diaz
Single-cell transcriptomic data have rapidly become very popular in genomic science. Genomic science also has a long history of using network models to understand the way in which genes work together to carry out specific biological functions. However, working with single-cell data presents major challenges, such as zero inflation and technical noise. These challenges require methods to be specifically adapted to the context of single-cell data. Recently, much effort has been made to develop the theory behind statistical network models...
November 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29116975/progress-on-a-new-kind-of-progress-test-assessing-medical-students-clinical-skills
#20
Robin H DeMuth, Jonathan G Gold, Brian E Mavis, Dianne P Wagner
PROBLEM: Progress testing of medical knowledge has advantages over traditional medical school examination strategies. However, little is known about its use in assessing medical students' clinical skills or their integration of clinical skills with necessary science knowledge. The authors previously reported on the feasibility of the Progress Clinical Skills Examination (PCSE), piloted with a group of early learners. This subsequent pilot test studied the exam's validity to determine whether the PCSE is sensitive to the growth in students' clinical skills across the four years of medical school...
November 7, 2017: Academic Medicine: Journal of the Association of American Medical Colleges
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