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https://www.readbyqxmd.com/read/29044156/open-source-3d-multipurpose-measurement-system-with-submillimetre-fidelity-and-first-application-in-magnetic-resonance
#1
Haopeng Han, Raphael Moritz, Eva Oberacker, Helmar Waiczies, Thoralf Niendorf, Lukas Winter
Magnetic resonance imaging (MRI) is the mainstay of diagnostic imaging, a versatile instrument for clinical science and the subject of intense research interest. Advancing clinical science, research and technology of MRI requires high fidelity measurements in quantity, location and time of the given physical property. To meet this goal a broad spectrum of commercial measurement systems has been made available. These instruments frequently share in common that they are costly and typically employ closed proprietary hardware and software...
October 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29043325/a-fully-integrated-microfluidic-platform-for-highly-sensitive-analysis-of-immunochemical-parameters
#2
Sascha Lutz, Eloisa Lopez-Calle, Pamela Espindola, Christoph Boehm, Thorsten Brueckner, Juergen Spinke, Moritz Marcinowski, Thomas Keller, Armin Tgetgel, Nicolas Herbert, Thomas Fischer, Erik Beiersdorf
We present a novel fully integrated centrifugal microfluidic platform for highly sensitive immunoassays in point-of-care settings. The platform consists of a disposable cartridge containing structures for assay processing, a porous membrane and all dried reagents required for the analysis. Additionally, a blister containing a washing buffer is connected to a new aliquoting structure enabling the serial aliquoting of washing buffer for repetitive bound-free separation steps. The proof-of-concept for two immunoassays is shown in the cartridge with each requiring only 30 μL of whole blood or plasma as the sample material...
October 18, 2017: Analyst
https://www.readbyqxmd.com/read/29042471/measuring-patient-perception-of-quality-in-a-radiology-department-by-adapting-a-standardized-industry-proven-tool
#3
Farouk Dako, Rick Wray, Omer Awan, Rathan M Subramaniam
Introduction: Our study quantitatively measures patient perception of quality and satisfaction in a PET-CT center at the point of care using a psychometrically validated questionnaire, SERVPERF, to guide subsequent quality improvement interventions. SERVPERF is a survey instrument that captures service quality by measuring performance of various services. It has demonstrated reliability and validity across various industries including healthcare, banking, transportation, telecommunication and higher education...
October 17, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/29040923/six-factors-of-adult-dyslexia-assessed-by-cognitive-tests-and-self-report-questions-very-high-predictive-validity
#4
Peter Tamboer, Harrie C M Vorst, Peter F de Jong
The Multiple Diagnostic Digital Dyslexia Test for Adults (MDDDT-A) consists of 12 newly developed tests and self-report questions in the Dutch language. Predictive validity and construct validity were investigated and compared with validity of a standard test battery of dyslexia (STB) in a sample of 154 students. There are three main results. First, various analyses of principal components showed that six or more factors of dyslexia can be distinguished (rapid naming, spelling, reading, short-term memory, confusion, phonology, attention, complexity)...
October 14, 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/29039828/-clinical-laboratory-and-instrumental-criteria-for-myocarditis-established-in-comparison-with-myocardial-biopsy-a-non-invasive-diagnostic-algorithm
#5
O V Blagova, Yu V Osipova, A V Nedostup, E A Kogan, V A Sulimov
AIM: To determine the diagnostic value of different clinical, laboratory, and instrumental signs in the diagnosis of myocarditis in patients with the picture of idiopathic arrhythmias, dilated cardiomyopathy (DCM) and in a comparison group when comparing with myocardial morphological examination. SUBJECTS AND METHODS: A study group included 100 patients (35 women; mean age, 44.7±12.5 years) with idiopathic arrhythmias (n=20) and DCM as a syndrome (n=100). All underwent myocardial morphological examination: endomyocardial biopsy (EMB) (n=71), intraoperative biopsy (n=13), study of the explanted heart (n=6), and autopsy (n=11)...
2017: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/29039144/transoral-endoscopic-thyroidectomy-via-a-vestibular-approach-why-and-how
#6
Gianlorenzo Dionigi, Young Jun Chai, Ralph P Tufano, Angkoon Anuwong, Hoon Yub Kim
The transoral endoscopic thyroidectomy vestibular approach (TOETVA) is a novel, scar-free surgical procedure that does not require visible incisions. Indications for TOETVA are as follows: predicted gland width on diagnostic imaging ≤10 cm; a thyroid volume outline of <45 mL or dominant nodule dimension of ≤50 mm; three or four Bethesda lesions; a primary papillary microcarcinoma without local or distant metastasis; and patient request for optimal esthetic results. Contraindications are as follows: patients unfit for general anesthesia; precedent radiation in the head, neck, upper mediastinum; antecedent neck surgery; recurrent goiter; a gland volume of >45 mL or main nodule diameter of >50 mm; and documentation of lymph node or distant metastases, tracheal/esophageal infiltration, preoperative laryngeal nerve palsy, hyperthyroidism, mediastinal goiter, or an oral abscess...
October 16, 2017: Endocrine
https://www.readbyqxmd.com/read/29035957/diagnostic-test-accuracy-of-self-reported-frailty-screening-instruments-in-identifying-community-dwelling-older-people-at-risk-of-frailty-and-pre-frailty-a-systematic-review-protocol
#7
Rachel C Ambagtsheer, Mark Q Thompson, Mandy M Archibald, Mavourneen G Casey, Timothy J Schultz
The question of this systematic review is: What is the diagnostic test accuracy of self-reported frailty screening instruments among community-dwelling older people against any of the following reference standard tests: the frailty phenotype, frailty index and comprehensive geriatric assessment?
October 2017: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/29034303/validation-of-capillary-blood-analysis-and-capillary-testing-mode-on-the-epoc-point-of-care-system
#8
Jing Cao, Rachel Edwards, Janette Chairez, Sridevi Devaraj
BACKGROUND: Laboratory test in transport is a critical component of patient care, and capillary blood is a preferred sample type particularly in children. This study evaluated the performance of capillary blood testing on the epoc Point of Care Blood Analysis System (Alere Inc). METHODS: Ten fresh venous blood samples was tested on the epoc system under the capillary mode. Correlation with GEM 4000 (Instrumentation Laboratory) was examined for Na+, K+, Cl-, Ca2+, glucose, lactate, hematocrit, hemoglobin, pO2, pCO2, and pH, and correlation with serum tested on Vitros 5600 (Ortho Clinical Diagnostics) was examined for creatinine...
December 2017: Pract Lab Med
https://www.readbyqxmd.com/read/29032455/electrochemical-aptamer-based-biosensor-developed-to-monitor-psa-and-vegf-released-by-prostate-cancer-cells
#9
Bruno P Crulhas, Agnieszka E Karpik, Flávia K Delella, Gustavo R Castro, Valber A Pedrosa
Early prostate cancer (PCa) diagnostic is crucial to enhance patient survival rates; besides, non-invasive platforms have been developed worldwide in order to precisely detect PCa biomarkers. Therefore, the aim of the present study is to develop a new aptamer-based biosensor through the self-assembling of thiolated aptamers for PSA and VEGF on the top of gold electrodes. This biosensor was tested in three prostate cell lines (RWPE-1, LNCaP and PC3). The results evidenced a stable and sensitive sensor presenting wide linear detection ranges (0...
October 14, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/29028087/axillary-ectopic-lobular-carcinoma-of-breast-two-rare-case-reports
#10
A Conversi, M L Meggiorini, P Fino, G Soda, N Scuderi, M G Onesti
OBJECTIVE: The presence of ectopic or supernumerary breast tissue is a rare event, related to a not complete regression of breast tissue along the milk line. Primary ectopic breast cancer of the axilla can create many difficulties in differential diagnosis with subsequent delayed specific treatments. The incidence of ectopic breast tissue is 0.2-6%, and the axilla is the most common site involved. In this tissue, the same physiologic and pathologic changes as seen in ectopic breast tissue may occur, including carcinoma formation...
September 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29027590/diagnostic-utility-of-combined-retinal-ganglion-cell-count-estimates-in-japanese-glaucoma-patients
#11
Mari Sakamoto, Sotaro Mori, Kaori Ueda, Azusa Akashi, Yukako Inoue, Takuji Kurimoto, Akiyasu Kanamori, Yuko Yamada, Makoto Nakamura
PURPOSE: To assess the combined estimate of retinal ganglion cell (RGC) count developed by Medeiros et al. as a tool for diagnosis of glaucoma in Japanese patients. STUDY DESIGN: Cross-sectional study. METHODS: Thirty-one eyes of 19 healthy controls and 106 eyes of 70 glaucoma patients underwent standard automated perimetry (SAP) and three types of spectral domain optical coherence tomography (SD-OCT) imaging using the Cirrus, RTVue, and 3D-OCT instruments...
October 13, 2017: Japanese Journal of Ophthalmology
https://www.readbyqxmd.com/read/29026763/comparative-evaluation-of-indian-diabetes-risk-score-and-finnish-diabetes-risk-score-for-predicting-risk-of-diabetes-mellitus-type-ii-a-teaching-hospital-based-survey-in-maharashtra
#12
Shivshakti D Pawar, Jayashri D Naik, Priya Prabhu, Gajanan M Jatti, Sachin B Jadhav, B K Radhe
CONTEXT: India is currently becoming capital for diabetes mellitus. This significantly increasing incidence of diabetes putting an additional burden on health care in India. Unfortunately, half of diabetic individuals are unknown about their diabetic status. Hence, there is an emergent need of effective screening instrument to identify "diabetes risk" individuals. AIMS: The aim is to evaluate and compare the diagnostic accuracy and clinical utility of Indian Diabetes Risk Score (IDRS) and Finnish Diabetes Risk Score (FINDRISC)...
January 2017: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/29026084/binary-temporal-upconversion-codes-of-mn-2-activated-nanoparticles-for-multilevel-anti-counterfeiting
#13
Xiaowang Liu, Yu Wang, Xiyan Li, Zhigao Yi, Renren Deng, Liangliang Liang, Xiaoji Xie, Daniel T B Loong, Shuyan Song, Dianyuan Fan, Angelo H All, Hongjie Zhang, Ling Huang, Xiaogang Liu
Optical characteristics of luminescent materials, such as emission profile and lifetime, play an important role in their applications in optical data storage, document security, diagnostics, and therapeutics. Lanthanide-doped upconversion nanoparticles are particularly suitable for such applications due to their inherent optical properties, including large anti-Stokes shift, distinguishable spectroscopic fingerprint, and long luminescence lifetime. However, conventional upconversion nanoparticles have a limited capacity for information storage or complexity to prevent counterfeiting...
October 12, 2017: Nature Communications
https://www.readbyqxmd.com/read/29024444/role-of-esophagogastroduodenoscopy-in-detecting-distal-duodenal-lesions-a-single-center-pilot-study-in-south-china
#14
Weiguang Qiao, Zemin Han, Yutang Ren, Tongyin Xing, Wenxin Tan, Side Liu, Fachao Zhi
OBJECTIVE: Esophagogastroduodenoscopy (EGD) is the standard instrument to detect diseases of the upper digestive tract. However, the deep areas of the duodenum are often missed. This study aimed to clarify the diagnostic role of EGD in the distal duodenum. METHODS: This retrospective study enrolled 63 patients with distal duodenal lesions between January 2004 and July 2016. Rate of missed diagnosis on EGD examination was calculated. Logistic regression analysis was performed to identify factors associated with missed diagnosis...
October 12, 2017: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/29023568/demonstrating-the-reliability-of-transdiagnostic-mhealth-routine-outcome-monitoring-in-mental-health-services-using-experience-sampling-technology
#15
Simone J W Verhagen, Juliënne A Berben, Carsten Leue, Anne Marsman, Philippe A E G Delespaul, Jim van Os, Richel Lousberg
BACKGROUND: Routine Outcome Monitoring (ROM) should provide a dynamic, within-treatment forward feedback loop to guide individual treatment decisions across diagnostic categories. It has been suggested that the Experience Sampling Method (ESM), capturing the film of daily life adaptive processes, offers a flexible, personalised and transdiagnostic feedback system for monitoring and adapting treatment strategies. This is the first study that uses an ESM application (the PsyMate™) as a routine mobile-ROM (mROM) tool in an ambulatory mental health setting...
2017: PloS One
https://www.readbyqxmd.com/read/29020840/self-determining-medical-leadership-needs-of-occupational-health-physicians
#16
Prosenjit Giri, Jill Aylott, Karen Kilner
Purpose The purpose of this study was to explore which factors motivate doctors to engage in leadership roles and to frame an inquiry of self-assessment within Self-Determination Theory (SDT) to identify the extent to which a group of occupational health physicians (OHPs) was able to self-determine their leadership needs, using a National Health Service (NHS) England competency approach promoted by the NHS England Leadership Academy as a self-assessment leadership diagnostic. Medical leadership is seen as crucial to the transformation of health-care services, yet leadership programmes are often designed with a top-down and centrally commissioned "one-size-fits-all" approach...
October 12, 2017: Leadership in Health Services
https://www.readbyqxmd.com/read/29019477/comparing-axis-ii-scores-according-to-the-rdc-tmd-and-dc-tmd-in-israeli-patients
#17
Shoshana Reiter, Ilana Eli, Pessia Friedman-Rubin, Alona Emodi-Perlman, Tomer Ziv-Baran, Ephraim Winocur
AIMS: To use the Symptom Checklist-90-Revised (SCL-90-R)-based instruments of the Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD) and the Primary Care Evaluation of Mental Disorders (PRIME-MD)-based instruments of the Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) in order to compare these Axis II scores in temporomandibular disorder (TMD) patients. METHODS: Demographic and socioeconomic data, Axis I diagnoses, and Axis II evaluations (depression, nonspecific physical symptoms, anxiety, and Graded Chronic Pain Scale [GCPS]) were compared between two groups of patients-142 TMD patients diagnosed according to the RDC/TMD (RDC group) and 157 TMD patients diagnosed according to the DC/TMD (DC group)...
October 10, 2017: Journal of Oral & Facial Pain and Headache
https://www.readbyqxmd.com/read/28994755/foodborne-pathogen-screening-using-magneto-fluorescent-nanosensor-rapid-detection-of-e-coli-o157-h7
#18
Tyler Shelby, Shoukath Sulthana, James McAfee, Tuhina Banerjee, Santimukul Santra
Enterohemorrhagic Escherichia coli O157:H7 has been linked to both waterborne and foodborne illnesses, and remains a threat despite the food- and water-screening methods used currently. While conventional bacterial detection methods, such as polymerase chain reaction (PCR) and enzyme-linked immunosorbent assays (ELISA) can specifically detect pathogenic contaminants, they require extensive sample preparation and lengthy waiting periods. In addition, these practices demand sophisticated laboratory instruments and settings, and must be executed by trained professionals...
September 17, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28992657/-competing-validity-of-developmental-diagnostic-in-school-entry-examination-results-of-a-census-in-an-upper-bavarian-district
#19
Heribert Stich, Kristin Maria Schlinkmann, Rafael Mikolajczyk
Aim of the study Evaluation of the concurrent validity of a modified Bavarian model (BM) compared to the social-paediatric screening of developmental status for school entry (SOPESS) as a reference tool. Methods A total of 407 preschoolers to be enrolled for the school year 2015 in an Upper Bavarian District were examined by BM and SOPESS. As a measure of the concurrent validity, the Kappa by Cohen (ĸ) was used. Results The agreement of both instruments was moderate and was less pronounced for single dimensions than globally...
October 9, 2017: Das Gesundheitswesen
https://www.readbyqxmd.com/read/28988826/clinical-diagnostic-tools-for-vitamin-d-assessment
#20
Iltaf Shah, M Kalim Akhtar, Soleiman Hisaindee, Muhammad A Rauf, Mohammed Sadig, S Salman Ashraf
Vitamin D deficiency has been implicated in a plethora of diseases including rheumatoid arthritis, Parkinson's disease, Alzheimer's disease, and osteoporosis. Deficiency of this vitamin is a global epidemic affecting both developing and developed nations. Within a clinical context, the qualitative and quantitative analysis of vitamin D is therefore vital. The main metabolic markers for assessing vitamin D status in humans are the hydroxylated forms of vitamin D, 25OHD3 and 25OHD2 on account of their long half-lives within the body and excellent stability...
October 5, 2017: Journal of Steroid Biochemistry and Molecular Biology
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