keyword
MENU ▼
Read by QxMD icon Read
search

Clinical diagnostics

keyword
https://www.readbyqxmd.com/read/28551938/-horizontal-canal-benign-paroxysmal-positional-vertigo-hc-bppv-clinical-diagnostic-procedures
#1
REVIEW
Oz Zur, Ophir Ilan, Hadas Ben-Rubi Shimron, Eli Carmeli
Horizontal canal benign paroxysmal positional vertigo (HCBPPV) is one form of benign paroxysmal positional vertigo. HC-BPPV is characterized by intermittent recurrent episodes of vertigo following a change in head position relative to gravity. HC-BPPV prevalence ranges from 5%-33% of all dizziness cases seen in otolaryngology, neurology and family physician clinics. Various factors, such as ear and head injury, can cause HC-BPPV. Cardiovascular disease and iatrogenic reasons are also implicated. Despite the prevalence of the disease, there are various forms of diagnostic procedures, some of which are unfamiliar to the therapist and some are controversial...
March 2017: Harefuah
https://www.readbyqxmd.com/read/28551930/-laboratory-tests-and-radiological-imaging-diagnostic-tools-that-share-information-and-can-be-functionally-integrated
#2
Michael Mayer
In spite of apparent disparity between the specialties of radiological imaging, pathology and laboratory analysis, the medical diagnostic information that these sources provide have a lot in common and can be effectively utilized by sharing quantitative and qualitative results through modern information technology processes. Informaticsbased integration of radiological imaging, digital images of anatomical and molecular pathology and clinical laboratory results enables earlier, more sensitive and precise diagnosis, resulting in the more efficient treatment of patients...
March 2017: Harefuah
https://www.readbyqxmd.com/read/28551919/-utilization-of-whole-exome-sequencing-in-diagnostics-of-genetic-disease-rabin-medical-center-s-experience
#3
Lior Cohen, Naama Orenstein, Monica Weisz-Hubshman, Lily Bazak, Bella Davidov, Eyal Reinstein, Shay Tzur, Doron Behar, Pola Smirin-Yosef, Mali Salmon-Divon, Amit Gross, Mordechai Shohat, Lina Basel-Vanagaite
INTRODUCTION: Whole exome sequencing is a diagnostic approach for the identification of molecular etiology in patients with suspected monogenic diseases. In this article we report on our experience with whole-exome sequencing (WES) of DNA samples taken from patients referred for genetic evaluation due to suspected undiagnosed genetic conditions. METHODS: Exome enrichment was achieved by Nextera Rapid Capture Expanded Exome Kit. Whole-exome sequencing was performed on Illumina HiSeq 2500...
April 2017: Harefuah
https://www.readbyqxmd.com/read/28551915/-characteristics-of-large-pericardial-effusion-in-a-well-defined-geographical-region
#4
Moanis Serhan, Ruhi Abdallah, Shaul Atar
BACKGROUND: Pericardial effusion can occur as a result of primary pericardial disease or secondary to systemic disease. Analysis of the features of pericardial effusion in correlation with clinical and demographic findings can help clinicians to determine the correct diagnosis and to choose the appropriate treatment and reduce patient mortality and morbidity. METHODS: Retrospective analysis of the characteristics of pericardial effusion and the prevalence of the different etiologies and their correlation with demographics, clinical characteristics and medical history in 86 patients admitted to Galilee Medical Center from 2001 to 2010 who underwent pericardiocentesis or pericardial window...
May 2017: Harefuah
https://www.readbyqxmd.com/read/28551834/increased-bone-tracer-uptake-in-symptomatic-patients-with-acl-graft-insufficiency-a-correlation-of-mri-and-spect-ct-findings
#5
Dominic T Mathis, Anna Hirschmann, Anna L Falkowski, Tommi Kiekara, Felix Amsler, Helmut Rasch, Michael T Hirschmann
PURPOSE: Magnetic resonance imaging (MRI) and single-photon emission computerised tomography/computerised tomography (SPECT/CT) are used as diagnostic tools in symptomatic patients after reconstruction of the anterior cruciate ligament (ACL). The benefit of SPECT/CT in comparison with MRI is under debate. The purpose of this study was to investigate whether and how bone tracer uptake (BTU) intensity and distribution in SPECT/CT correlate with MRI findings in symptomatic patients after ACL reconstruction...
May 27, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28551829/meta-analysis-of-the-effects-of-genetic-polymorphisms-on-intervertebral-disc-degeneration
#6
J Rigal, A Léglise, T Barnetche, A Cogniet, S Aunoble, J C Le Huec
INTRODUCTION: Chronic low back pain is a significant public health issue. Both its direct and indirect cost represents tens of billions of US dollars. Although chronic low back pain can be the result of many factors, the predominant cause is disc degeneration. Recent studies have shown genetic involvement in up to 74% of cases. This study aimed to evaluate genetic risk factors of disc degeneration by performing a systematic analysis of association studies. The objective is to provide a guide for practice by assessing the clinical relevance of current information...
May 27, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28551736/back-pain-with-leg-pain
#7
REVIEW
Simon Vulfsons, Negev Bar, Elon Eisenberg
PURPOSE OF REVIEW: The clinical diagnostic dilemma of low back pain that is associated with lower limb pain is very common. In relation to back pain that radiates to the leg, the International Association for the Study of Pain (IASP) states: "Pain in the lower limb should be described specifically as either referred pain or radicular pain. In cases of doubt no implication should be made and the pain should be described as pain in the lower limb." RECENT FINDINGS: Bogduks' editorial in the journal PAIN (2009) helps us to differentiate and define the terms somatic referred pain, radicular pain, and radiculopathy...
July 2017: Current Pain and Headache Reports
https://www.readbyqxmd.com/read/28551709/the-validity-of-a-new-structured-assessment-of-gastrointestinal-symptoms-scale-sagis-for-evaluating-symptoms-in-the-clinical-setting
#8
N A Koloski, M Jones, J Hammer, M von Wulffen, A Shah, H Hoelz, M Kutuyla, D Burger, N Martin, S R Gurusamy, N J Talley, G Holtmann
BACKGROUND: The clinical assessments of patients with gastrointestinal symptoms can be time-consuming, and the symptoms captured during the consultation may be influenced by a variety of patient and non-patient factors. To facilitate standardized symptom assessment in the routine clinical setting, we developed the Structured Assessment of Gastrointestinal Symptom (SAGIS) instrument to precisely characterize symptoms in a routine clinical setting. AIMS: We aimed to validate SAGIS including its reliability, construct and discriminant validity, and utility in the clinical setting...
May 27, 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28551691/meckel-s-diverticulum-a-congenital-defect-of-the-gastrointestinal-tract-underestimated-in-differential-diagnostics-own-experience
#9
Jolanta Pietrzak, Anna Obuchowicz, Dariusz Majda, Andrzej Kiedos
Meckel's diverticulum is a vestigial remnant of the omphalomesenteric duct. It is the most frequent defect of the gastrointestinal tract and is present in approx. 2% of the population: more often in boys than in girls, at a 3:1 ratio. Meckel's diverticulum causes clinical symptoms only in 4-6% of individuals. It is situated approximately 60-100 cm away from the Bauhin's valve. The wall of Meckel's diverticulum consists of all layers typical of the small intestine. It is usually approx. 2-3 cm long, but it can reach lengths of over 10 centimetres...
2017: Developmental Period Medicine
https://www.readbyqxmd.com/read/28551486/qualitative-agreement-and-diagnostic-performance-of-arterial-spin-labelling-mri-and-fdg-pet-ct-in-suspected-early-stage-dementia-comparison-of-arterial-spin-labelling-mri-and-fdg-pet-ct-in-suspected-dementia
#10
Kathleen Weyts, Meike Vernooij, Rebecca Steketee, Roelf Valkema, Marion Smits
18FDG PET-CT is useful for early and differential diagnosis of dementia. ASL-MRI seems an attractive alternative. Visual agreement was calculated in 21 brain regions bilaterally in 9/11 patients with suspected early-stage dementia, excluding 2 patients due to ASL-MRI motion artefacts. Overall gross agreement was almost perfect and identical between and within modalities (κ=0.85-0.86, p<0.05). Intermodality regional agreement was variable, moderate (κ=0,56 in posterior cingulate) to perfect (including in precuneus), not different from intramodality agreement...
May 19, 2017: Clinical Imaging
https://www.readbyqxmd.com/read/28551387/clinical-and-pathological-characteristic-of-metastatic-malignant-mesothelioma-initially-diagnosed-by-lymph-node-biopsy
#11
Xiang-Lan Zhu, Li-Min Gao, Fen Li, Wei-Ping Liu, Wen-Yan Zhang, Gan-Di Li, Xiu-Hui Zhang, Min Chen, Xiao-Yu Liu, Sha Zhao
BACKGROUND: It is a great challenge for pathologists to initially diagnose metastatic malignant mesothelioma (MM) by the lymph node biopsy without any history of primary MM. Because the onset of MM is hidden and the metastatic MM in lymph node is relatively uncommon. Besides, morphologic and immuohistochemistry features of MM are similar to other tumors. METHODS: In order to improve the initial diagnostic accuracy of metastatic MM from LN biopsy and to reduce or avoid the possibility of missed diagnosis or misdiagnosis, we had collected the clinical and pathological data of the metastatic MM cases in our department, and summarized the characteristics of morphological, immunohistochemical and fluorescence in situ hybridization (FISH) results...
May 13, 2017: Pathology, Research and Practice
https://www.readbyqxmd.com/read/28551330/histopathologic-evaluation-of-atypical-neurofibromatous-tumors-and-their-transformation-into-malignant-peripheral-nerve-sheath-tumor-in-neurofibromatosis-1-patients-a-consensus-overview
#12
Markku M Miettinen, Cristina R Antonescu, Christopher D M Fletcher, Aerang Kim, Alexander J Lazar, Martha M Quezado, Karlyne M Reilly, Anat Stemmer-Rachamimov, Douglas R Stewart, David Viskochil, Brigitte Widemann, Arie Perry
Neurofibromatosis 1 (NF1) patients develop multiple neurofibromas, with 8-15% of patients experiencing malignant peripheral nerve sheath tumor (MPNST) during their lifetime. Prediction of transformation, typically from plexiform neurofibroma, is clinically and histologically challenging. In this overview, following a consensus meeting in October 2016, we outline the histopathologic features and molecular mechanisms involved in the malignant trans-formation of neurofibromas. Nuclear atypia alone is generally insignificant...
May 24, 2017: Human Pathology
https://www.readbyqxmd.com/read/28551326/appendiceal-goblet-cell-carcinoid-common-errors-in-staging-and-clinical-interpretation-with-a-proposal-for-an-improved-terminology
#13
Kwun Wah Wen, Gillian Hale, Nafis Shafizadeh, Mojgan Hosseini, Anne Huang, Sanjay Kakar
Goblet cell carcinoid (GCC) is staged and treated as adenocarcinoma (AC) and not as neuroendocrine tumor (NET) or neuroendocrine carcinoma. The term 'carcinoid' may lead to incorrect interpretation as NET. To explore pitfalls in staging and clinical interpretation of GCC and mixed GCC-AC, and propose strategies to avoid common errors. Diagnostic terminology, staging and clinical interpretation were evaluated in 58 cases (27 GCC, 31 mixed GCC-AC). Opinions were collected from 23 pathologists using a survey. Clinical notes were reviewed to assess the interpretation of pathology diagnoses by oncologists...
May 24, 2017: Human Pathology
https://www.readbyqxmd.com/read/28551282/bowel-bladder-dysfunction-and-numbness-in-the-sole-of-the-both-feet-in-lumbar-spinal-stenosis-a-multicenter-cross-sectional-study
#14
Kazuyuki Watanabe, Miho Sekiguchi, Koji Yonemoto, Takuya Nikaido, Kinshi Kato, Koji Otani, Shoji Yabuki, Tatsuyuki Kakuma, Shin-Ichi Kikuchi, Shin-Ichi Konno
BACKGROUND: Numbness in the soles of both feet at rest or bowel/bladder dysfunction can occur in patients with lumbar spinal stenosis (LSS), especially in patients with cauda equina lesions. The purpose of this study was to clarify the relationship between cauda equina symptoms at rest and quality of life (QOL) in LSS patients using standardized questionnaires developed for the Japanese population. METHODS: A survey was conducted in 564 hospitals and general practice clinics nationwide from December 1, 2011 to December 31, 2012...
May 24, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/28551140/continuous-and-simultaneous-determination-of-venous-blood-metabolites
#15
Anneli Andersson, Qun Chen, Leif Groop, Leif Bülow, Bin Xie
Metabolic syndrome is associated with cardiovascular disease, type 2 diabetes mellitus (T2DM) and prediabetes. Metabolic syndrome is a cluster of interrelated clinical disorders. Difficulties in regulating glucose levels in blood are implicated in many of these disorders. Lactate, another energy metabolite, is produced under anaerobic conditions and can be used to monitor the balance between aerobic and anaerobic metabolism. Tested together, these metabolite levels can provide pro-diagnostic information that improves patient outcomes...
August 15, 2017: Talanta
https://www.readbyqxmd.com/read/28551075/diagnostic-accuracy-of-post-mortem-ct-with-targeted-coronary-angiography-versus-autopsy-for-coroner-requested-post-mortem-investigations-a-prospective-masked-comparison-study
#16
Guy N Rutty, Bruno Morgan, Claire Robinson, Vimal Raj, Mini Pakkal, Jasmin Amoroso, Theresa Visser, Sarah Saunders, Mike Biggs, Frances Hollingbury, Angus McGregor, Kevin West, Cathy Richards, Laurence Brown, Rebecca Harrison, Roger Hew
BACKGROUND: England and Wales have one of the highest frequencies of autopsy in the world. Implementation of post-mortem CT (PMCT), enhanced with targeted coronary angiography (PMCTA), in adults to avoid invasive autopsy would have cultural, religious, and potential economic benefits. We aimed to assess the diagnostic accuracy of PMCTA as a first-line technique in post-mortem investigations. METHODS: In this single-centre (Leicester, UK), prospective, controlled study, we selected cases of natural and non-suspicious unnatural death referred to Her Majesty's (HM) Coroners...
May 24, 2017: Lancet
https://www.readbyqxmd.com/read/28551047/clinical-predictors-of-nodal-metastases-in-peripherally-clinical-t1a-n0-non-small-cell-lung-cancer
#17
Galal Ghaly, Mohamed Rahouma, Mohamed K Kamel, Abu Nasar, Sebron Harrison, Andrew B Nguyen, Jeffrey Port, Brendon M Stiles, Nasser K Altorki, Paul C Lee
BACKGROUND: Despite the relatively high sensitivity of fluorodeoxyglucose-positron emission tomography (PET) and computed tomography (CT) scans used for staging of non-small cell lung cancer (NSCLC), a subset of patients with peripherally located clinical T1a N0 will be upstaged due to pathologic nodal disease. It is important to study this risk of upstaging, especially if local treatments, such as wedge resection or stereotactic body radiation therapy, are potential treatment modalities...
May 24, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28550993/barriers-to-pcsk9-inhibitor-prescriptions-for-patients-with-high-cardiovascular-risk-results-of-a-healthcare-provider-survey-conducted-by-the-national-lipid-association
#18
Jerome D Cohen, Mark J Cziraky, Terry A Jacobson, Kevin C Maki, Dean G Karalis
BACKGROUND: Statin therapy is recommended for reducing atherosclerotic cardiovascular disease (ASCVD) risk. Significant risk can remain because of insufficient clinical response or statin intolerance. Proprotein convertase subtilisin/kexin type-9 (PCSK9) therapy lowers low-density lipoprotein cholesterol and has recently been shown to lower ASCVD events. OBJECTIVE: The aim of the study was to assess the barriers and challenges experienced with the access and approval reimbursement process for PCSK9 inhibitor prescriptions...
May 23, 2017: Journal of Clinical Lipidology
https://www.readbyqxmd.com/read/28550987/molecular-diagnostics-and-lack-of-clinical-allergy-in-helminth-endemic-areas-in-indonesia
#19
Firdaus Hamid, Serge A Versteeg, Aprilianto E Wiria, Linda J Wammes, Sitti Wahyuni, Taniawati Supali, Erliyani Sartono, Ronald van Ree, Maria Yazdanbakhsh
Allergen microarray characterization of sensitization to common allergen sources in a helminth-endemic area of Indonesia shows that helminth induced cross-reactivity to cross-reactive carbohydrate determinants (CCD), and not primary sensitization to their major allergens, is the dominant feature.
May 24, 2017: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28550940/invasive-sinonasal-lesions-from-the-nasal-fossa-and-paranasal-sinuses-to-the-endocranium
#20
REVIEW
Pablo Naval Baudin, Albert Pons Escoda, Mònica Cos Domingo, Mario Huete Naval, Carles Majós, Carles Aguilera
The aim of this work is to review the spectrum of sinonasal lesions that extend to the endocranium and to present key points that may narrow the differential diagnosis. The most frequent sinonasal lesions that extend into the endocranium are malignant; however, benign entities are not unusual. Imaging diagnosis is difficult because malignant lesions and benign entities share similar clinical, epidemiologic, and imaging features. Tumor features in relation to bone, intratumor homogeneity and structure, magnetic resonance imaging signal, along with clinical and epidemiologic aspects may allow an appropriate diagnostic focus with important management implications...
April 8, 2017: Current Problems in Diagnostic Radiology
keyword
keyword
13742
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"