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https://www.readbyqxmd.com/read/29026767/socioeconomic-determinants-affecting-the-quality-of-life-among-diabetic-and-hypertensive-patients-in-a-rural-area-egypt
#1
Hewaida M ElShazly, Nagwa Nashat Hegazy
BACKGROUND: Diabetes mellitus and hypertension have a high prevalence of growth in all countries threatening to become a global epidemic risk, thus the quality of life this category of patients is extremely important. The aim of this study was to assess the socioeconomic determinants affecting the quality of life among diabetic and hypertensive patients. PATIENT AND METHODS: A descriptive cross-sectional study was conducted in a rural family health care center in El-Batanon village, in the delta region of Menoufia, Egypt...
January 2017: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/28978580/use-of-optokinetics-based-okcsib-protocol-in-restoring-mobility-in-primary-progressive-ms
#2
Benjamin Chitambira, Ciara McConaghy
The case is of a mid-40s patient who developed progressive muscle weakness and loss of mobility over 6 weeks due to primary progressive multiple sclerosis. 2.5 days before admission, she became bed bound with weakness of 1/5 on the Oxford scale. She normally rested for a couple of days after similar periods of worsening symptoms and then got back on her feet although with worse balance. She was treated with optokinetic chart stimulation and sensory interaction for balance (OKCSIB) protocol. Within 2 days of intervention, she was mobile with a delta frame and supervision of one...
October 4, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28812206/differences-in-femoral-neck-structure-between-elderly-caucasian-and-chinese-populations-a-cross-sectional-study-of-perth-beijing-cohorts
#3
L Wang, B C C Khoo, X G Cheng, K Brown, J R Lewis, Y B Su, Z Guo, K Li, R L Prince
Structural skeletal differences of the femoral neck of older Beijing-Chinese and Perth-Caucasian women were compared; adjusting for frame size-related differences, Beijing-Chinese have lower periosteal width; however, indices of internal bone distribution suggest that Beijing-Chinese may exhibit increased resistance to fracture that may relate to the reduced hip fracture incidence. INTRODUCTION: Ethnic differences in skeletal structure may relate to differences in hip fracture risk in Chinese and Caucasian populations...
August 15, 2017: Archives of Osteoporosis
https://www.readbyqxmd.com/read/28652318/a-framework-for-quantification-and-physical-modeling-of-cell-mixing-applied-to-oscillator-synchronization-in-vertebrate-somitogenesis
#4
Koichiro Uriu, Rajasekaran Bhavna, Andrew C Oates, Luis G Morelli
In development and disease, cells move as they exchange signals. One example is found in vertebrate development, during which the timing of segment formation is set by a 'segmentation clock', in which oscillating gene expression is synchronized across a population of cells by Delta-Notch signaling. Delta-Notch signaling requires local cell-cell contact, but in the zebrafish embryonic tailbud, oscillating cells move rapidly, exchanging neighbors. Previous theoretical studies proposed that this relative movement or cell mixing might alter signaling and thereby enhance synchronization...
August 15, 2017: Biology Open
https://www.readbyqxmd.com/read/28580339/can-evolutionary-based-brain-map-be-used-as-a-complementary-diagnostic-tool-with-fmri-ct-and-pet-for-schizophrenic-patients
#5
R Boostani, M Sabeti
OBJECTIVE: In this research, a new approach termed as "evolutionary-based brain map" is presented as a diagnostic tool to classify schizophrenic and control subjects by distinguishing their electroencephalogram (EEG) features. METHODS: Particle swarm optimization (PSO) is employed to find discriminative frequency bands from different EEG channels. By deploying the energy of those selected frequency bands from different channels within each time frame (window) on the scalp geometry, a sort of two dimensional points along with their values are created; by applying Lagrange interpolation, an image can be constructed...
June 2017: Journal of Biomedical Physics & Engineering
https://www.readbyqxmd.com/read/28574466/a-robust-96-6-db-sndr-50-khz-bandwidth-switched-capacitor-delta-sigma-modulator-for-ir-imagers-in-space-instrumentation
#6
Michele Dei, Stepan Sutula, Jose Cisneros, Ernesto Pun, Richard Jan Engel Jansen, Lluís Terés, Francisco Serra-Graells
Infrared imaging technology, used both to study deep-space bodies' radiation and environmental changes on Earth, experienced constant improvements in the last few years, pushing data converter designers to face new challenges in terms of speed, power consumption and robustness against extremely harsh operating conditions. This paper presents a 96.6-dB-SNDR (Signal-to-Noise-plus-Distortion Ratio) 50-kHz-bandwidth fourth-order single-bit switched-capacitor delta-sigma modulator for ADC operating at 1.8 V and consuming 7...
June 2, 2017: Sensors
https://www.readbyqxmd.com/read/28490916/the-cannabis-withdrawal-syndrome-current-insights
#7
REVIEW
Udo Bonnet, Ulrich W Preuss
The cannabis withdrawal syndrome (CWS) is a criterion of cannabis use disorders (CUDs) (Diagnostic and Statistical Manual of Mental Disorders - Fifth Edition) and cannabis dependence (International Classification of Diseases [ICD]-10). Several lines of evidence from animal and human studies indicate that cessation from long-term and regular cannabis use precipitates a specific withdrawal syndrome with mainly mood and behavioral symptoms of light to moderate intensity, which can usually be treated in an outpatient setting...
2017: Substance Abuse and Rehabilitation
https://www.readbyqxmd.com/read/27684742/production-of-materials-with-spatially-controlled-cross-link-density-via-vat-photopolymerization
#8
Gregory I Peterson, Johanna J Schwartz, Di Zhang, Benjamin M Weiss, Mark A Ganter, Duane W Storti, Andrew J Boydston
We describe an efficient method to produce objects comprising spatially controlled and graded cross-link densities using vat photopolymerization additive manufacturing (AM). Using a commercially available diacrylate-based photoresin, 3D printer, and digital light processing (DLP) projector, we projected grayscale images to print objects in which the varied light intensity was correlated to controlled cross-link densities and associated mechanical properties. Cylinder and bar test specimens were used to establish correlations between light intensities used for printing and cross-link density in the resulting specimens...
October 11, 2016: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/27648476/detection-and-mapping-of-cannabinoids-in-single-hair-samples-through-rapid-derivatization-and-matrix-assisted-laser-desorption-ionization-mass-spectrometry
#9
Emma Beasley, Simona Francese, Tom Bassindale
The sample preparation method reported in this work has permitted for the first time the application of matrix-assisted laser desorption ionization mass spectrometry (MALDI-MS) profiling and imaging for the detection and mapping of cannabinoids in a single hair sample. MALDI-MS imaging analysis of hair samples has recently been suggested as an alternative technique to traditional methods of GC/MS and LC/MS due to simpler sample preparation, the ability to detect a narrower time frame of drug use, and a reduction in sample amount required...
October 18, 2016: Analytical Chemistry
https://www.readbyqxmd.com/read/27597254/driving-under-the-effect-of-drugs-hair-analysis-in-order-to-evaluate-recidivism
#10
Giovanna Tassoni, Marta Cippitelli, Dora Mirtella, Rino Froldi, Giovanni Ottaviani, Massimiliano Zampi, Mariano Cingolani
Under Italian law drug addiction and regular drug abuse are incompatible with driving ability. One important problem with the enforcement of the impaired driving law is the large number of people that re-offend. To regain their license, offenders must be drug-free for the duration of an observation period, according to the judgement of a medical commission. The exclusion of illicit drug use is determined by toxicological analysis. A few studies exist that have used a hair matrix to monitor recidivism. Hair is an attractive matrix for monitoring drug recidivism, due to the large time window for drug detection, and to the non-alterability of this matrix...
October 2016: Forensic Science International
https://www.readbyqxmd.com/read/27511048/small-world-characteristics-of-cortical-connectivity-changes-in-acute-stroke
#11
Pietro Caliandro, Fabrizio Vecchio, Francesca Miraglia, Giuseppe Reale, Giacomo Della Marca, Giuseppe La Torre, Giordano Lacidogna, Chiara Iacovelli, Luca Padua, Placido Bramanti, Paolo Maria Rossini
Background After cerebral ischemia, disruption and subsequent reorganization of functional connections occur both locally and remote to the lesion. Recently, complexity of brain connectivity has been described using graph theory, a mathematical approach that depicts important properties of complex systems by quantifying topologies of network representations. Functional and dynamic changes of brain connectivity can be reliably analyzed via electroencephalography (EEG) recordings even when they are not yet reflected in structural changes of connections...
January 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/27416620/current-status-of-frameless-anchored-iud-for-immediate-intracesarean-insertion
#12
Dirk Wildemeersch, Norman D Goldstuck, Thomas Hasskamp
Immediate postpartum intrauterine device (IUD) insertion deserves great attention as it can provide immediate, timely and convenient contraception plus the added benefit of preventing repeat unintended pregnancies. Although women post vaginal delivery can benefit from immediate post-placenta contraception, women undergoing Cesarean section clearly need contraception, as an inter-delivery interval shorter than 18 months places them at a high risk for uterine rupture. The main drawback of currently available framed IUD devices for immediate postpartum insertion of an IUD is their high expulsion and displacement rates when inserted immediately postpartum after both vaginal and Cesarean delivery...
January 2016: Developmental Period Medicine
https://www.readbyqxmd.com/read/27108112/delta-like-1-homolog-in-capra-hircus-molecular-characteristics-expression-pattern-and-phylogeny
#13
Jiangtao Hu, Wei Zhao, Siyuan Zhan, Ping Xiao, Jingxuan Zhou, Linjie Wang, Li Li, Hongping Zhang, Lili Niu, Tao Zhong
To research the molecular characteristics, expression pattern and phylogeny of the Delta-like 1 homolog gene (Dlk1) in goats. Dlk1 transcripts were identified in the Jianyang Da'er goats by reverse-transcription polymerase chain reaction (RT-PCR). Phylogenetic trees were constructed by Bayesian inference and neighbor-joining methods. Quantitative real-time PCR (qPCR), western blotting and in situ hybridization were performed to analyze the expression pattern of Dlk1. Five alternatively transcripts were identified in different tissues and designated as Dlk1-AS1, 2, 3, 4 and 5...
June 2016: Molecular Biology Reports
https://www.readbyqxmd.com/read/26955362/brain-oscillations-in-sport-toward-eeg-biomarkers-of-performance
#14
REVIEW
Guy Cheron, Géraldine Petit, Julian Cheron, Axelle Leroy, Anita Cebolla, Carlos Cevallos, Mathieu Petieau, Thomas Hoellinger, David Zarka, Anne-Marie Clarinval, Bernard Dan
Brain dynamics is at the basis of top performance accomplishment in sports. The search for neural biomarkers of performance remains a challenge in movement science and sport psychology. The non-invasive nature of high-density electroencephalography (EEG) recording has made it a most promising avenue for providing quantitative feedback to practitioners and coaches. Here, we review the current relevance of the main types of EEG oscillations in order to trace a perspective for future practical applications of EEG and event-related potentials (ERP) in sport...
2016: Frontiers in Psychology
https://www.readbyqxmd.com/read/26660178/quantification-of-11-carboxy-delta-9-tetrahydrocannabinol-thc-cooh-in-meconium-using-gas-chromatography-mass-spectrometry-gc-ms
#15
Judy Peat, Brehon Davis, Clint Frazee, Uttam Garg
Maternal substance abuse is an ongoing concern and detecting drug use during pregnancy is an important component of neonatal care when drug abuse is suspected. Meconium is the preferred specimen for drug testing because it is easier to collect than neonatal urine and it provides a much broader time frame of drug exposure. We describe a method for quantifying 11-carboxy-delta-9-tetrahydrocannabinol (THC-COOH) in meconium. After adding a labeled internal standard (THC-COOH D9) and acetonitrile, samples are sonicated to release both free and conjugated THC-COOH...
2016: Methods in Molecular Biology
https://www.readbyqxmd.com/read/26657387/heavy-metal-contents-distribution-and-prediction-in-a-regional-soil-wheat-system
#16
Jing Ran, Dejian Wang, Can Wang, Gang Zhang, Hailin Zhang
The entry of heavy metals into the food chain is of concern for potential health risks. To investigate the spatial relationships of heavy metals in a regional soil-wheat system, 99 pairs of surface soil (0-15 cm) and wheat grain samples were collected from Changshu, China, a typical county in the Yangtze Delta region. Both soil and wheat grain samples were analyzed for total Cd, Cu, Ni, Pb, and Zn. DTPA-extractable metals and major physico-chemical properties were also determined for soil samples. Moderate accumulation of heavy metals was found in soils and wheat grains, especially Cd...
February 15, 2016: Science of the Total Environment
https://www.readbyqxmd.com/read/26568914/hepatitis-delta-virus-a-fascinating-and-neglected-pathogen
#17
REVIEW
Celso Cunha, João Paulo Tavanez, Severin Gudima
Hepatitis delta virus (HDV) is the etiologic agent of the most severe form of virus hepatitis in humans. Sharing some structural and functional properties with plant viroids, the HDV RNA contains a single open reading frame coding for the only virus protein, the Delta antigen. A number of unique features, including ribozyme activity, RNA editing, rolling-circle RNA replication, and redirection for a RNA template of host DNA-dependent RNA polymerase II, make this small pathogen an excellent model to study virus-cell interactions and RNA biology...
November 12, 2015: World Journal of Virology
https://www.readbyqxmd.com/read/26457879/investigation-of-phase-mixing-in-amorphous-solid-dispersions-of-amg-517-in-hpmc-as-using-dsc-solid-state-nmr-and-solution-calorimetry
#18
Julie L Calahan, Stephanie C Azali, Eric J Munson, Karthik Nagapudi
Intimate phase mixing between the drug and the polymer is considered a prerequisite to achieve good physical stability for amorphous solid dispersions. In this article, spray dried amorphous dispersions (ASDs) of AMG 517 and HPMC-as were studied by differential scanning calorimetry (DSC), solid-state NMR (SSNMR), and solution calorimetry. DSC analysis showed a weakly asymmetric (ΔTg ≈ 13.5) system with a single glass transition for blends of different compositions indicating phase mixing. The Tg-composition data was modeled using the BKCV equation to accommodate the observed negative deviation from ideality...
November 2, 2015: Molecular Pharmaceutics
https://www.readbyqxmd.com/read/26241977/one-pass-mode-and-motion-decision-for-multilayer-quality-scalable-video-coding
#19
Meng Xu, Zhan Ma, Yao Wang
This paper presents a novel low-complexity motion estimation and mode decision algorithm for encoding multiple quality layers following the H.264/scalable video coding standard, considering both coarse grain scalability (CGS) and medium grain scalability (MGS). The proposed algorithm conducts motion estimation and mode decision only at the base layer (BL) and enforces the higher layers to inherit the motion and mode decisions of the BL. In order for the decision made at the BL to be nearly optimal for all layers, we use the highest layer reconstructed frame as the reference frame for motion estimation and set the Lagrangian multipliers according to the quantization parameter of the current and higher layers...
November 2015: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/26207828/predicted-shifts-in-small-mammal-distributions-and-biodiversity-in-the-altered-future-environment-of-alaska-an-open-access-data-and-machine-learning-perspective
#20
A P Baltensperger, F Huettmann
Climate change is acting to reallocate biomes, shift the distribution of species, and alter community assemblages in Alaska. Predictions regarding how these changes will affect the biodiversity and interspecific relationships of small mammals are necessary to pro-actively inform conservation planning. We used a set of online occurrence records and machine learning methods to create bioclimatic envelope models for 17 species of small mammals (rodents and shrews) across Alaska. Models formed the basis for sets of species-specific distribution maps for 2010 and were projected forward using the IPCC (Intergovernmental Panel on Climate Change) A2 scenario to predict distributions of the same species for 2100...
2015: PloS One
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