keyword
https://read.qxmd.com/read/38346037/correction-associations-between-social-isolation-index-and-changes-in-grip-strength-gait-speed-bone-mineral-density-bmd-and-self-reported-incident-fractures-among-older-adults-results-from-the-canadian-longitudinal-study-on-aging-clsa
#21
Ahreum Lee, Caitlin McArthur, George Ioannidis, Alexandra Mayhew, Jonathan D Adachi, Lauren E Griffith, Lehana Thabane, Alexandra Papaioannou
[This corrects the article DOI: 10.1371/journal.pone.0292788.].
2024: PloS One
https://read.qxmd.com/read/38340814/sonocatalytic-degradation-of-bisphenol-a-from-aquatic-matrices-over-pd-ceo-2-nanoparticles-kinetics-study-transformation-products-and-toxicity
#22
JOURNAL ARTICLE
Alexandra A Ioannidi, Georgios Bampos, Maria Antonopoulou, Paula Oulego, Grzegorz Boczkaj, Dionisios Mantzavinos, Zacharias Frontistis
In this work, different ratios of palladium - cerium oxide (Pd/CeO2 ) catalyst were synthesized and characterized, while their sonocatalytic activity was evaluated for the degradation of the xenobiotic Bisphenol A (BPA) from aqueous solutions. Sonocatalytic activity expressed as BPA decomposition exhibited a volcano-type behavior in relation to the Pd loading, and the 0.25Pd/CeO2 catalyst characterized by the maximum Pd dispersion and lower crystallite size demonstrated the higher activity. Using 500 mg/L of 0...
February 8, 2024: Science of the Total Environment
https://read.qxmd.com/read/38338370/extraction-optimization-and-qualitative-quantitative-determination-of-bioactive-abietane-type-diterpenes-from-three-salvia-species-common-sage-greek-sage-and-rosemary-by-1-h-qnmr
#23
JOURNAL ARTICLE
Panagiotis Kallimanis, Prokopios Magiatis, Angeliki Panagiotopoulou, Kostas Ioannidis, Ioanna Chinou
The objective of this study was the optimization of the extraction process and the qualitative and quantitative determination of the bioactive metabolites: 12- O -methylcarnosic acid (12MCA), carnosic acid (CA), carnosol (CS), 7- O -methyl- epi -rosmanol (7MER) and rosmanol (RO) in infusions, decoctions, turbulent flow extracts, tinctures and oleolites from three Salvia species: Salvia officinalis L. (common sage, SO ), Salvia fruticosa Mill. (Greek sage, SF ) and Salvia rosmarinus Spenn (syn Rosmarinus officinalis L...
January 28, 2024: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://read.qxmd.com/read/38337557/biliary-anatomy-visualization-and-surgeon-satisfaction-using-standard-cholangiography-versus-indocyanine-green-fluorescent-cholangiography-during-elective-laparoscopic-cholecystectomy-a-randomized-controlled-trial
#24
JOURNAL ARTICLE
Savvas Symeonidis, Ioannis Mantzoros, Elissavet Anestiadou, Orestis Ioannidis, Panagiotis Christidis, Stefanos Bitsianis, Konstantinos Zapsalis, Trigona Karastergiou, Dimitra Athanasiou, Stylianos Apostolidis, Stamatios Angelopoulos
Background : Intraoperative biliary anatomy recognition is crucial for safety during laparoscopic cholecystectomy, since iatrogenic bile duct injuries represent a fatal complication, occurring in up to 0.9% of patients. Indocyanine green fluorescence cholangiography (ICG-FC) is a safe and cost-effective procedure for achieving a critical view of safety and recognizing early biliary injuries. The aim of this study is to compare the perioperative outcomes, usefulness and safety of standard intraoperative cholangiography (IOC) with ICG-FC with intravenous ICG...
February 1, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38328983/superficial-acral-calcified-chondroid-mesenchymal-neoplasm-harboring-an-fn1-fgfr2-fusion-and-review-of-the-literature
#25
Isidro Machado, Vasileia Damaskou, Eleftherios Ioannidis, George Jour, Konstantinos Linos
Calcified chondroid mesenchymal neoplasm is a recently recognized bone and soft tissue entity primarily found in the extremities and the temporomandibular joint. This neoplasm is typically driven by the fusion of the FN1 gene with a kinase. In this case report, we provide a detailed account of a rare superficial calcified chondroid mesenchymal neoplasm located on the left big toe, characterized by an FN1::FGFR2 fusion. The tumor exhibited a peripheral collarette and consisted of large intradermal histiocytoid to epithelioid cells with no mitotic activity...
February 8, 2024: Journal of Cutaneous Pathology
https://read.qxmd.com/read/38327122/footprint-of-publication-selection-bias-on-meta-analyses-in-medicine-environmental-sciences-psychology-and-economics
#26
JOURNAL ARTICLE
František Bartoš, Maximilian Maier, Eric-Jan Wagenmakers, Franziska Nippold, Hristos Doucouliagos, John P A Ioannidis, Willem M Otte, Martina Sladekova, Teshome K Deresssa, Stephan B Bruns, Daniele Fanelli, T D Stanley
Publication selection bias undermines the systematic accumulation of evidence. To assess the extent of this problem, we survey over 68,000 meta-analyses containing over 700,000 effect size estimates from medicine (67,386/597,699), environmental sciences (199/12,707), psychology (605/23,563), and economics (327/91,421). Our results indicate that meta-analyses in economics are the most severely contaminated by publication selection bias, closely followed by meta-analyses in environmental sciences and psychology, whereas meta-analyses in medicine are contaminated the least...
February 7, 2024: Research Synthesis Methods
https://read.qxmd.com/read/38327090/analysis-of-insecticide-resistance-and-de-novo-transcriptome-assembly-of-resistance-associated-genes-in-the-european-grapevine-moth-lobesia-botrana-lepidoptera-tortricidae
#27
JOURNAL ARTICLE
Esra Albaz, Evangelia Katsavou, Naciye Sena Cagatay, Panagiotis Ioannidis, Aris Ilias, Kyriaki Mylona, Katerina Kremi, Emmanouil Roditakis, Nurper Guz, John Vontas
The European grapevine moth Lobesia botrana (Denis & Shiffermüller 1776) is an economically important pest of the vine-growing areas worldwide. Chemical insecticides have been used for its control; however, its resistance status is largely unknown in many regions. We monitored the susceptibility of several L. botrana populations from Greece and Turkey. In addition, based on RNAseq transcriptome analysis, we identified and phylogenetically classify the cytochrome P450 genes of L. botrana , as well as analysed target site sequences and looked for the presence of known resistance mutations...
February 8, 2024: Bulletin of Entomological Research
https://read.qxmd.com/read/38322086/incidental-petrous-apex-cephalocele-presenting-with-transient-global-amnesia-a-case-report-and-rapid-literature-review
#28
Alexandros Brotis, Mariana Vlychou, Ioannis Ioannidis
Transient global amnesia (TGA) constitutes a rare clinical entity that manifests with temporary memory without any other neurological manifestation. Several pathogenetic mechanisms have been implicated, including temporal hypoperfusion, venous congestion, and cortical spreading potentials. Accordingly, the only relevant imaging findings are hippocampal CA1 areas of restricted diffusion on diffusion-weighted images. In the current case report, we present the rare case of a patient with TGA associated with bilateral petrous apex cephalocele (PAC)...
January 2024: Curēus
https://read.qxmd.com/read/38316844/author-correction-mortality-outcomes-with-hydroxychloroquine-and-chloroquine-in-covid-19-from-an-international-collaborative-meta-analysis-of-randomized-trials
#29
Cathrine Axfors, Andreas M Schmitt, Perrine Janiaud, Janneke Van't Hooft, Sherief Abd-Elsalam, Ehab F Abdo, Benjamin S Abella, Javed Akram, Ravi K Amaravadi, Derek C Angus, Yaseen M Arabi, Shehnoor Azhar, Lindsey R Baden, Arthur W Baker, Leila Belkhir, Thomas Benfield, Marvin A H Berrevoets, Cheng-Pin Chen, Tsung-Chia Chen, Shu-Hsing Cheng, Chien-Yu Cheng, Wei-Sheng Chung, Yehuda Z Cohen, Lisa N Cowan, Olav Dalgard, Fernando F de Almeida E Val, Marcus V G de Lacerda, Gisely C de Melo, Lennie Derde, Vincent Dubee, Anissa Elfakir, Anthony C Gordon, Carmen M Hernandez-Cardenas, Thomas Hills, Andy I M Hoepelman, Yi-Wen Huang, Bruno Igau, Ronghua Jin, Felipe Jurado-Camacho, Khalid S Khan, Peter G Kremsner, Benno Kreuels, Cheng-Yu Kuo, Thuy Le, Yi-Chun Lin, Wu-Pu Lin, Tse-Hung Lin, Magnus Nakrem Lyngbakken, Colin McArthur, Bryan J McVerry, Patricia Meza-Meneses, Wuelton M Monteiro, Susan C Morpeth, Ahmad Mourad, Mark J Mulligan, Srinivas Murthy, Susanna Naggie, Shanti Narayanasamy, Alistair Nichol, Lewis A Novack, Sean M O'Brien, Nwora Lance Okeke, Léna Perez, Rogelio Perez-Padilla, Laurent Perrin, Arantxa Remigio-Luna, Norma E Rivera-Martinez, Frank W Rockhold, Sebastian Rodriguez-Llamazares, Robert Rolfe, Rossana Rosa, Helge Røsjø, Vanderson S Sampaio, Todd B Seto, Muhammad Shahzad, Shaimaa Soliman, Jason E Stout, Ireri Thirion-Romero, Andrea B Troxel, Ting-Yu Tseng, Nicholas A Turner, Robert J Ulrich, Stephen R Walsh, Steve A Webb, Jesper M Weehuizen, Maria Velinova, Hon-Lai Wong, Rebekah Wrenn, Fernando G Zampieri, Wu Zhong, David Moher, Steven N Goodman, John P A Ioannidis, Lars G Hemkens
No abstract text is available yet for this article.
February 5, 2024: Nature Communications
https://read.qxmd.com/read/38302928/an-empirical-comparison-of-statistical-methods-for-multiple-cut-off-diagnostic-test-accuracy-meta-analysis-of-the-edinburgh-postnatal-depression-scale-epds-depression-screening-tool-using-published-results-vs-individual-participant-data
#30
JOURNAL ARTICLE
Zelalem F Negeri, Brooke Levis, John P A Ioannidis, Brett D Thombs, Andrea Benedetti
BACKGROUND: Selective reporting of results from only well-performing cut-offs leads to biased estimates of accuracy in primary studies of questionnaire-based screening tools and in meta-analyses that synthesize results. Individual participant data meta-analysis (IPDMA) of sensitivity and specificity at each cut-off via bivariate random-effects models (BREMs) can overcome this problem. However, IPDMA is laborious and depends on the ability to successfully obtain primary datasets, and BREMs ignore the correlation between cut-offs within primary studies...
February 1, 2024: BMC Medical Research Methodology
https://read.qxmd.com/read/38296509/alt-in-combination-with-triple-rolled-tfl-for-reconstruction-of-a-complex-tendoachilles-defect-technical-details-and-rehabilitation-regime
#31
JOURNAL ARTICLE
Zahra Ahmed, Hannah Cook, Meera Anadkat, Lydia Ioannidi, Helen Marmery, Dariush Nikkhah
A fit man in his 60s presented with an infected Achilles tendon (AT) following two failed repairs for a traumatic rupture. Initial debridement of necrotic tissue resulted in a large soft tissue defect requiring robust coverage. Following aggressive wound management, an anterolateral thigh flap was elevated with tensor fasciae latae (TFL) which was triple-rolled to provide soft tissue coverage and tendon reconstruction.The flap remained healthy and was monitored with a flow coupler device. Initially, the foot was placed in plantarflexion before gradually increasing the angle to neutral and a thermoplastic splint was used to offload pressure on the flap...
January 31, 2024: BMJ Case Reports
https://read.qxmd.com/read/38269372/personalized-and-longitudinal-electronic-informed-consent-in-clinical-trials-how-to-move-the-needle
#32
JOURNAL ARTICLE
Evelien De Sutter, Liese Barbier, Pascal Borry, David Geerts, John P A Ioannidis, Isabelle Huys
Changes in the clinical trials landscape have been driven by advancements in digital technology. The use of electronic informed consent to inform research participants and to obtain their consent electronically has the potential to improve participant-researcher interactions over time, facilitate clinical trial participation, and increase efficiency in clinical trial conduct. A personalized electronic informed consent platform that enables long-term interactions with the research team could function as a tool to empower participant engagement in clinical trials...
2024: Digital Health
https://read.qxmd.com/read/38255980/acute-antiplatelet-effects-of-an-oleocanthal-rich-olive-oil-in-type-ii-diabetic-patients-a-postprandial-study
#33
JOURNAL ARTICLE
Maria Efthymia Katsa, Kleopatra Ketselidi, Marianna Kalliostra, Anastasios Ioannidis, Andrea Paola Rojas Gil, Panagiotis Diamantakos, Eleni Melliou, Prokopios Magiatis, Tzortzis Nomikos
Postprandial dysmetabolism is a common entity of type 2 diabetes mellitus (T2DM) and may act as a daily stressor of the already dysfunctional diabetic platelets. This study aims to investigate whether oleocanthal-rich olive oils (OO), incorporated into a carbohydrate-rich meal, can affect postprandial dysmetabolism and platelet aggregation. Oleocanthal is a cyclooxygenase inhibitor with putative antiplatelet properties. In this randomized, single-blinded, crossover study, ten T2DM patients consumed five isocaloric meals containing 120 g white bread combined with: (i) 39 g butter, (ii) 39 g butter and 400 mg ibuprofen, (iii) 40 mL OO (phenolic content < 10 mg/Kg), (iv) 40 mL OO with 250 mg/Kg oleocanthal and (v) 40 mL OO with 500 mg/Kg oleocanthal...
January 11, 2024: International Journal of Molecular Sciences
https://read.qxmd.com/read/38230225/the-effectiveness-of-metabolic-bariatric-surgery-in-preventing-gynecologic-cancer-from-pathophysiology-to-clinical-outcomes
#34
REVIEW
Nikolaos Machairiotis, Athanasios G Pantelis, Anastasios Potiris, Theodoros Karampitsakos, Petros Drakakis, Eirini Drakaki, Panagoula Oikonomou, Christina Nikolaou, Dimitrios Matthaios, Charalampos Charalampidis, Aris Ioannidis, Paul Zarogoulidis, Stavros Sofoklis
Obesity and cancer represent two pandemics of current civilization, the progression of which has followed parallel trajectories. To time, thirteen types of malignancies have been recognized as obesity-related cancers, including breast (in postmenopausal women), endometrial, and ovarian cancer. Pathophysiologic mechanisms that connect the two entities include insulin resistance, adipokine imbalance, increased peripheral aromatization and estrogen levels, tissue hypoxia, and disrupted immunity in the cellular milieu...
2024: Journal of Cancer
https://read.qxmd.com/read/38230209/ablation-for-single-pulmonary-nodules-primary-or-metastatic-%C3%AE-ndobronchial-ablation-systems-or-percutaneous
#35
JOURNAL ARTICLE
Paul Zarogoulidis, Vasilis Papadopoulos, Eleni-Isidora Perdikouri, Anastasios Vagionas, Dimitris Matthaios, Aris Ioannidis, Wolfgang Hohemforst-Schmidt, Haidong Huang, Chong Bai, Oikonomou Panagoula, Christina Nikolaou, Charalampos Charalampidis, Christoforos Kosmidis, Konstantinos Sapalidis, Nikolaos Machairiotis, Athanasia Pataka
Single pulmonary nodules are a difficult to diagnose imagining artifact. Currently novel diagnostic tools such as Radial-EBUS with or not C-ARM flouroscopy, electromagnetic navigation systems, robotic bronchoscopy and cone beam-compuer tomography (CBCT) can assist in the optimal guidance of biopsy equipment. After diagnosis of lung cancer or metastatic disease as pulmonary nodule, then surgery or ablation methods as local treatment can be applied. The percutaneous ablation systems under computed tomography guidance with radiofrequency, microwave, cryo and thermosphere have been used for several years...
2024: Journal of Cancer
https://read.qxmd.com/read/38214191/screening-for-executive-impairment-in-patients-with-frontotemporal-dementia-evidence-from-the-greek-version-of-the-frontier-executive-screen
#36
JOURNAL ARTICLE
Eleni Konstantinopoulou, Vilou Irini, Falega Ioanna, Papadopoulou Valentina, Hatzidimitriou Electra, Grigoriadis Nikolaos, Aretouli Eleni, Panagiotis Ioannidis
OBJECTIVES: The aim of the present study was to adjust the frontier executive screen (FES) for the Greek population, to develop normative data, and to investigate its ability to discriminate patients diagnosed with frontotemporal dementia from healthy individuals. METHODS: The FES was administered to 142 community-dwelling healthy adults (age: M = 65.9, SD = 8.5; education: M = 10.8, SD = 4.3; sex: 59% female) and 32 patients diagnosed with frontotemporal dementia (age: M = 69...
January 11, 2024: Archives of Clinical Neuropsychology: the Official Journal of the National Academy of Neuropsychologists
https://read.qxmd.com/read/38213718/simultaneous-resection-for-colorectal-and-liver-metastases-new-equipment-and-personalized-medicine
#37
JOURNAL ARTICLE
Paul Zarogoulidis, Aris Ioannidis, Anastasios Vagionas, Eleni Isidora Perdikouri, Vagelis Christakidis, Marios Anemoulis, Isaak Kesisoglou, Dimitris Matthaios, Panagoula Oikonomou, Christina Nikolaou, Lavrentios Papalavrentios, Charalampos Charalampidis, Nikolaos Machairiotis, Vasilis Papadopoulos, Konstantinos Sapalidis
Nowadays we perform synchronous colorectal cancer resection along with synchronous liver metastases. We investigated whether colon resection first is safer than liver resection first and if simultaneous surgeries are in general safe. Patients and Methods: Twenty patients were included in our multicenter study. In our study patients had simultaneous laparoscopic resection of primary colorectal cancer and liver metastases. The patients included were divided into two groups based on their first surgery. Group A had colon resection first (n = 10) and group B had liver resection first (n = 10)...
2024: Journal of Cancer
https://read.qxmd.com/read/38195174/availability-of-evidence-and-comparative-effectiveness-for-surgical-versus-drug-interventions-an-overview-of-systematic-reviews-and-meta-analyses
#38
JOURNAL ARTICLE
Emmanuel A Zavalis, Anaïs Rameau, Anirudh Saraswathula, Joachim Vist, Ewoud Schuit, John P Ioannidis
OBJECTIVES: This study aims to examine the prevalence of comparisons of surgery to drug regimens, the strength of evidence of such comparisons and whether surgery or the drug intervention was favoured. DESIGN: Systematic review of systematic reviews (umbrella review). DATA SOURCES: Cochrane Database of Systematic Reviews. ELIGIBILITY CRITERIA: Systematic reviews attempt to compare surgical to drug interventions. DATA EXTRACTION: We extracted whether the review found any randomised controlled trials (RCTs) for eligible comparisons...
January 9, 2024: BMJ Open
https://read.qxmd.com/read/38187742/characterizing-uncertainty-in-predictions-of-genomic-sequence-to-activity-models
#39
Ayesha Bajwa, Ruchir Rastogi, Pooja Kathail, Richard W Shuai, Nilah M Ioannidis
Genomic sequence-to-activity models are increasingly utilized to understand gene regulatory syntax and probe the functional consequences of regulatory variation. Current models make accurate predictions of relative activity levels across the human reference genome, but their performance is more limited for predicting the effects of genetic variants, such as explaining gene expression variation across individuals. To better understand the causes of these shortcomings, we examine the uncertainty in predictions of genomic sequence-to-activity models using an ensemble of Basenji2 model replicates...
December 23, 2023: bioRxiv
https://read.qxmd.com/read/38185190/methods-proposed-for-monitoring-the-implementation-of-evidence-based-research-a-cross-sectional-study
#40
JOURNAL ARTICLE
Livia Puljak, Małgorzata M Bala, Joanna Zając, Tomislav Meštrović, Sandra Buttiġieġ, Mary Yanakoulia, Matthias Briel, Carole Lunny, Wiktoria Lesniak, Tina Poklepović Peričić, Pablo Alonso-Coello, Mike Clarke, Benjamin Djulbegovic, Gerald Gartlehner, Konstantinos Giannakou, Anne-Marie Glenny, Claire Glenton, Gordon Guyatt, Lars G Hemkens, John P A Ioannidis, Roman Jaeschke, Karsten Juhl Jørgensen, Carolina Castro Martins-Pfeifer, Ana Marušić, Lawrence Mbuagbaw, Jose Francisco Meneses Echavez, David Moher, Barbara Nussbaumer-Streit, Matthew J Page, Giordano Pérez-Gaxiola, Karen A Robinson, Georgia Salanti, Ian J Saldanha, Jelena Savović, James Thomas, Andrea C Tricco, Peter Tugwell, Joost van Hoof, Dawid Pieper
OBJECTIVES: Evidence-based research (EBR) is the systematic and transparent use of prior research to inform a new study so that it answers questions that matter in a valid, efficient, and accessible manner. This study surveyed experts about existing (e.g. citation analysis) and new methods for monitoring EBR and collected ideas about implementing these methods. STUDY DESIGN AND SETTING: We conducted a cross-sectional study via an online survey between November 2022 and March 2023...
January 5, 2024: Journal of Clinical Epidemiology
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