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https://www.readbyqxmd.com/read/28736204/neural-stability-a-reflection-of-automaticity-in-reading
#1
Silvia Siu-Yin Lam, Travis White-Schwoch, Steven G Zecker, Jane Hornickel, Nina Kraus
Automaticity, the ability to perform a task rapidly with minimal effort, plays a key role in reading fluency and is indexed by rapid automatized naming (RAN) and processing speed. Yet little is known about automaticity's neurophysiologic underpinnings. The more efficiently sound is encoded, the more automatic sound processing can be. In turn, this automaticity could free up cognitive resources such as attention and working memory to help build an integrative reading network. Therefore, we hypothesized that automaticity and reading fluency correlate with stable neural representation of sounds, given a larger body of literature suggesting the close relationship between neural stability and the integrative function in the central auditory system...
July 20, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/28728652/accuracy-of-fractional-flow-reserve-measurements-in-clinical-practice-observations-from-a-core-laboratory-analysis
#2
Mitsuaki Matsumura, Nils P Johnson, William F Fearon, Gary S Mintz, Gregg W Stone, Keith G Oldroyd, Bernard De Bruyne, Nico H J Pijls, Akiko Maehara, Allen Jeremias
OBJECTIVES: The aim of this study was to compare site-reported measurements of fractional flow reserve (FFR) with FFR analysis by an independent core laboratory (CL). BACKGROUND: FFR is an index of coronary stenosis severity that has been validated in multiple trials and is widely used in clinical practice. However, the incidence of suboptimal FFR measurements is unknown. METHODS: Patients undergoing FFR assessment within the CONTRAST (Can Contrast Injection Better Approximate FFR Compared to Pure Resting Physiology) study had paired, repeated measurements of multiple physiological metrics per local practice...
July 24, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28714527/multimodality-imaging-of-intermediate-lesions-data-from-ffr-oct-nirs-ivus
#3
Dariusz Biały, Magdalena Wawrzyńska, Jacek Arkowski, Marcin Rogała, Klaudia Proniewska, Wojciech Wańha, Wojciech Wojakowski, Tomasz Roleder
BACKGROUND: Fractional flow reserve (FFR) assesses a functional impact of the atheroma on the myocardial ischemia, but it does not take into account the morphology of the lesion. Previous optical coherence tomography (OCT), intravascular ultrasound (IVUS) and near infrared spectroscopy (NIRS) studies presented their potential to detect vulnerable plaque, which is not possible by FFR assessment. With the following study, the intermediate lesions were assessed by FFR, OCT and combined NIRS-IVUS imaging to identify plaque vulnerability...
July 17, 2017: Cardiology Journal
https://www.readbyqxmd.com/read/28699019/the-diagnostic-performance-of-spect-mpi-to-predict-functional-significant-coronary-artery-disease-by-fractional-flow-reserve-derived-from-ccta-ffrct-sub-analysis-from-accuracy-and-vct001-studies
#4
Rine Nakanishi, Kazuhiro Osawa, Indre Ceponiene, Glenn Huth, Jason Cole, Michael Kim, Negin Nezarat, Sina Rahmani, Dong Li, Souma Gupta, Campbell Rogers, Christopher Dailing, Matthew J Budoff
Although single photon emission computed tomography-myocardial perfusion image (SPECT-MPI) and fractional flow reserve (FFR) derived from coronary computed tomographic angiography (CCTA) (FFRCT) have permitted functional assessment of coronary artery disease (CAD), the concordance between these modalities has not been well described. The aim of this study is to compare SPECT-MPI and anatomical stenosis by CCTA and invasive coronary angiography to FFRCT for assessing functional significance of CAD. We identified 62 patients with suspected CAD who underwent ≥64 slice coronary CTA and SPECT-MPI within 3 months...
July 11, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28691907/prognosis-of-deferred-non-culprit-lesions-according-to-fractional-flow-reserve-in-patients-with-acute-coronary-syndrome
#5
Joo Myung Lee, Ki Hong Choi, Bon-Kwon Koo, Eun-Seok Shin, Chang-Wook Nam, Joon-Hyung Doh, Doyeon Hwang, Jonghanne Park, Jinlong Zhang, Hong-Seok Lim, Myeong-Ho Yoon, Seung-Jea Tahk
AIMS: There are limited data on the prognosis of deferred non-culprit lesions in patients with acute coronary syndrome (ACS) based on fractional flow reserve (FFR). We investigated the prognosis of deferred non-culprit lesions in ACS patients, compared with deferred lesions in patients with stable coronary artery disease (SCAD), on the basis of FFR. METHODS AND RESULTS: The clinical outcomes of 449 non-culprit lesions (301 patients with ACS) were compared with 2,484 lesions (1,295 patients with SCAD) in which revascularization was deferred on the basis of a high FFR (>0...
July 11, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28687539/visual-and-quantitative-assessment-of-coronary-stenoses-at-angiography-versus-fractional-flow-reserve-the-impact-of-risk-factors
#6
COMPARATIVE STUDY
Julien Adjedj, Panagiotis Xaplanteris, Gabor Toth, Angela Ferrara, Mariano Pellicano, Giovanni Ciccarelli, Vincent Floré, Emanuele Barbato, Bernard De Bruyne
BACKGROUND: The correlation between angiographic assessment of coronary stenoses and fractional flow reserve (FFR) is weak. Whether and how risk factors impact the diagnostic accuracy of angiography is unknown. We sought to evaluate the diagnostic accuracy of angiography by visual estimate and by quantitative coronary angiography when compared with FFR and evaluate the influence of risk factors (RF) on this accuracy. METHODS AND RESULTS: In 1382 coronary stenoses (1104 patients), percent diameter stenosis by visual estimation (DSVE) and by quantitative coronary angiography (DSQCA) was compared with FFR...
July 2017: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28685228/relationship-between-coronary-contrast-flow-quantitative-flow-ratio-and-myocardial-ischemia-assessed-by-spect-mpi
#7
Jeff M Smit, Gerhard Koning, Alexander R van Rosendael, Petra Dibbets-Schneider, Bart J Mertens, J Wouter Jukema, Victoria Delgado, Johan H C Reiber, Jeroen J Bax, Arthur J Scholte
PURPOSE: A new method has been developed to calculate fractional flow reserve (FFR) from invasive coronary angiography, the so-called "contrast-flow quantitative flow ratio (cQFR)". Recently, cQFR was compared to invasive FFR in intermediate coronary lesions showing an overall diagnostic accuracy of 85%. The purpose of this study was to investigate the relationship between cQFR and myocardial ischemia assessed by single-photon emission computed tomography myocardial perfusion imaging (SPECT MPI)...
July 6, 2017: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/28681057/comfort-and-exertion-while-using-filtering-facepiece-respirators-with-exhalation-valve-and-an-active-venting-system-among-male-military-personnel
#8
Melvin Seng, Liang En Wee, Xiahong Zhao, Alex R Cook, Sin Eng Chia, Vernon J Lee
INTRODUCTION: This study aimed to determine if disposable filtering facepiece respirators (FFRs), with exhalation valve (EV) and a novel active venting system (AVS), provided greater perceived comfort and exertion when compared to standard N95 FFRs without these features among male military personnel performing prolonged essential outdoor duties. METHODS: We used a randomised open-label controlled crossover study design to compare three FFR options: (a) standard FFR; (b) FFR with EV; and (c) FFR with EV+AVS...
July 6, 2017: Singapore Medical Journal
https://www.readbyqxmd.com/read/28679241/a-lumped-parameter-model-of-the-single-free-flooded-ring-transducer
#9
Kyounghun Been, Seungwon Nam, Haksue Lee, Hee-Seon Seo, Wonkyu Moon
A free-flooded ring (FFR) transducer can generate low-frequency sound in a small device and has a wide operating frequency bandwidth. Many studies have been performed that can predict the characteristics of an FFR transducer using analytical techniques and an equivalent circuit model (ECM), and methods to predict properties using numerical simulations have recently been developed. However, an ECM, a type of lumped parameter model (LPM), is still widely used to interpret the properties of such transducers in the design process...
June 2017: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/28674929/frequency-of-a-large-drift-caused-by-pressure-wire-using-optical-fibers
#10
Yoshiaki Kawase, Toru Tanigaki, Akihiro Hirakawa, Hiroyuki Omori, Tetsuo Hirata, Syuuichi Okamoto, Hideaki Ota, Jun Kikuchi, Munenori Okubo, Hiroki Kamiya, Masanori Kawasaki, Takahiko Suzuki, Hitoshi Matsuo
The frequency of a large pressure signal drift (PDs) caused by pressure wire using optical fibers and its effect on fractional flow reserve (FFR)-based decision-making is not clear. We used pressure wires using optical fibers as "workhorse wires" for 95 consecutive lesions. The wire was normalized at the tip of the guiding catheter just before performing the percutaneous coronary intervention (PCI) and was used without re-normalization until the end of the PCI. The drift value at the end of the procedures was evaluated...
July 3, 2017: Cardiovascular Intervention and Therapeutics
https://www.readbyqxmd.com/read/28666784/interpreting-results-of-coronary-computed-tomography-angiography-derived-fractional-flow-reserve-in-clinical-practice
#11
REVIEW
Mark G Rabbat, Daniel S Berman, Morton Kern, Gilbert Raff, Kavitha Chinnaiyan, Lynne Koweek, Leslee J Shaw, Philipp Blanke, Markus Scherer, Jesper M Jensen, John Lesser, Bjarne L Nørgaard, Gianluca Pontone, Bernard De Bruyne, Jeroen J Bax, Jonathon Leipsic
The application of computational fluid dynamics to coronary computed tomography angiography allows Fractional Flow Reserve (FFR) to be calculated non-invasively (FFRCT), enabling computation of FFR from coronary computed tomography angiography acquired at rest both for individual lesions as well as along the entire course of a coronary artery. FFRCT, validated in a number of accuracy studies and a large clinical utility trial, is beginning to penetrate clinical practice. Importantly, while accuracy trials compared FFRCT to invasively measured FFR at a single point in the coronary tree, clinical reports of FFRCT provide information regarding a patient's entire coronary vasculature...
June 23, 2017: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/28657951/firearm-deaths-in-america-can-we-learn-from-462-000-lives-lost
#12
Shelby Resnick, Randi N Smith, Jessica H Beard, Daniel Holena, Patrick M Reilly, C William Schwab, Mark J Seamon
OBJECTIVE: We sought to determine whether state firearm legislation correlated with firearm-related fatality rates (FFR) during a 15-year period. BACKGROUND: The politicized and controversial topic of firearm legislation has been grossly understudied when the relative impact of American firearm violence is considered. Scientific evidence regarding gun legislation effectiveness remains scant. METHODS: Demographic and intent data (1999-2013) were collected from the Centers for Disease Control and Prevention's Web-Based Injury Statistics Query and Reporting System database and compared by state firearm legislation rankings with respect to FFR...
June 27, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28655419/neural-representations-of-concurrent-sounds-with-overlapping-spectra-in-rat-inferior-colliculus-comparisons-between-temporal-fine-structure-and-envelope
#13
Lu Luo, Qian Wang, Liang Li
Perceptual segregation of multiple sounds, which overlap in both time and spectra, into individual auditory streams is critical for hearing in natural environments. Some cues such as interaural time disparities (ITDs) play an important role in the segregation, especially when sounds are separated in space. In this study, we investigated the neural representation of two uncorrelated narrowband noises that shared the identical spectrum in the rat inferior colliculus (IC) using frequency-following-response (FFR) recordings, when the ITD for each noise stimulus was manipulated...
June 17, 2017: Hearing Research
https://www.readbyqxmd.com/read/28653314/fractional-flow-reserve-based-therapy-in-patients-presenting-with-acute-coronary-syndrome-current-data-and-everyday-practice
#14
Grzegorz Zuk, Dariusz Ciecwierz, Natalia Cwalina, Marcin Gruchala, Florim Cuculi
Fractional flow reserve (FFR) is an evidence-based diagnostic tool of physiological significance of coronary artery stenosis in patients with stable coronary artery disease (CAD). Due to microvascular dysfunction in acute coronary syndrome (ACS), information obtained from FFR assessment could be less reliable and, thus, its clinical role remains controversial. Indeed, results of currently published studies are essentially discrepant. Only a few randomized clinical trials have been performed showing the efficacy of FFR-guided percutaneous coronary intervention (PCI) in ACS...
June 27, 2017: Cardiology Journal
https://www.readbyqxmd.com/read/28653312/link-of-renal-microcirculatory-dysfunction-to-increased-coronary-microcirculatory-resistance-in-hypertensive-patients
#15
Cong Lin, Pu Zhang, Yangjing Xue, Yinqing Huang, Kangting Ji
BACKGROUND: This study investigated the correlation between renal microcirculation and coronary microcirculation in hypertensive patients. METHODS: Participants consisted of 231 consecutive candidates who were referred to the Second Affiliated Hospital of Wenzhou Medical University from March 2014 to May 2016 for elective coronary angiography due to suspected myocardial ischemia. All participants were evaluated for the index of microvascular resistance (IMR), coronary flow reserve (CFR), and fractional flow reserve (FFR) using a pressure wire...
June 27, 2017: Cardiology Journal
https://www.readbyqxmd.com/read/28652031/the-utility-of-contrast-medium-fractional-flow-reserve-in-functional-assessment-of-coronary-disease-in-daily-practice
#16
Pieter Van Wyk, Aniket Puri, James Blake, John Michael Elliott, Dougal McClean, Muhammad Arshad, Jacalin Sutherland, Olivia Thacker, Tina Bailey, Ma Yi, David Smyth
BACKGROUND: Adenosine induced hyperaemic fractional flow reserve (aFFR) is a validated predictor of clinical outcome and part of routine interventional practice. Protocol issues associated with the adenosine infusion limit the use of aFFR in clinical practice. Contrast medium induced hyperaemic FFR (cFFR) is a simpler procedure from a practical standpoint. We compared the two in a real world setting. METHODS: We analysed 76 patients that had both cFFR and aFFR assessment of 100 angiographically indeterminate coronary stenosis...
April 22, 2017: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/28651849/meta-analysis-of-head-to-head-comparison-of-intracoronary-versus-intravenous-adenosine-for-the-assessment-of-fractional-flow-reserve
#17
Stefano Rigattieri, Giuseppe Biondi Zoccai, Alessandro Sciahbasi, Cristian Di Russo, Maria Cera, Roberto Patrizi, Silvio Fedele, Andrea Berni, Francesco Rocco Pugliese
Intravenous (IV) infusion of adenosine represents the gold standard for measuring fractional flow reserve (FFR). However, IV adenosine is more expensive and time-consuming compared with intracoronary (IC) boluses of adenosine. We conducted a meta-analysis of studies comparing IC with IV adenosine for FFR assessment in the same coronary lesions. We searched for studies comparing IC with IV adenosine and reporting absolute FFR values or rate of abnormal FFR for both routes. Prespecified subgroup analysis was performed to appraise studies using low-dose (<100 μg) or high-dose IC adenosine (≥100 μg)...
May 30, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28651585/a-vessel-length-based-method-to-compute-coronary-fractional-flow-reserve-from-optical-coherence-tomography-images
#18
Kyung Eun Lee, Seo Ho Lee, Eun-Seok Shin, Eun Bo Shim
BACKGROUND: Hemodynamic simulation for quantifying fractional flow reserve (FFR) is often performed in a patient-specific geometry of coronary arteries reconstructed from the images from various imaging modalities. Because optical coherence tomography (OCT) images can provide more precise vascular lumen geometry, regardless of stenotic severity, hemodynamic simulation based on OCT images may be effective. The aim of this study is to perform OCT-FFR simulations by coupling a 3D CFD model from geometrically correct OCT images with a LPM based on vessel lengths extracted from CAG data with clinical validations for the present method...
June 26, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28649949/diagnostic-performance-of-a-lattice-boltzmann-based-method-for-fast-ct-fractional-flow-reserve
#19
Andreas Giannopoulos, Anji Tang, Yin Ge, Michael Cheezum, Michael Steigner, Shinichiro Fujimoto, Kanako Kumamaru, Dante Chiappino, Daniele Della Latta, Sergio Berti, Sara Chiappino, Frank Rybicki, Simone Melchionna, Dimitrios Mitsouras
AIMS: Fractional flow reserve (FFR) estimated from coronary computed tomography angiography (CT-FFR) offers non-invasive detection of lesion-specific ischemia. We developed and validated a fast CT-FFR algorithm utilizing the Lattice-Boltzmann Method for blood flow simulation (LBM CT-FFR). METHODS AND RESULTS: 64 patients from 3 institutions with clinically-indicated CTA and invasive FFR measurement were retrospectively analyzed. CT-FFR was performed using an on-site tool interfacing with a commercial Lattice-Boltzmann fluid dynamics cloud-based platform...
June 27, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28649159/initial-simulated-ffr-investigation-using-flow-measurements-in-patient-specific-3d-printed-coronary-phantoms
#20
Lauren Shepard, Kelsey Sommer, Richard Izzo, Alexander Podgorsak, Michael Wilson, Zaid Said, Frank J Rybicki, Dimitrios Mitsouras, Stephen Rudin, Erin Angel, Ciprian N Ionita
PURPOSE: Accurate patient-specific phantoms for device testing or endovascular treatment planning can be 3D printed. We expand the applicability of this approach for cardiovascular disease, in particular, for CT-geometry derived benchtop measurements of Fractional Flow Reserve, the reference standard for determination of significant individual coronary artery atherosclerotic lesions. MATERIALS AND METHODS: Coronary CT Angiography (CTA) images during a single heartbeat were acquired with a 320×0...
February 11, 2017: Proceedings of SPIE
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