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https://www.readbyqxmd.com/read/28728371/expression-of-fox-related-genes-in-the-skin-follicles-of-inner-mongolia-cashmere-goat
#1
Wenjing Han, Xiaoyan Li, Lele Wang, Honghao Wang, Kun Yang, Zhixin Wang, Ruijun Wang, Rui Su, Zhihong Liu, Yanhong Zhao, Yanjun Zhang, Jinquan Li
Objective: The aim of this study was to investigate the expression of genes in cashmere goats at different periods of their fetal development. Methods: Bioinformatics analysis was used to evaluate data obtained by transcriptome sequencing of fetus skin samples collected from Inner Mongolia cashmere goats on days 45, 55, and 65 of fetal age. Results: We found that FoxN1, FoxE1, and FoxI3 genes of the Fox gene family were probably involved in the growth and development of the follicle and the formation of hair, which is consistent with previous findings...
June 27, 2017: Asian-Australasian Journal of Animal Sciences
https://www.readbyqxmd.com/read/28728330/hair-diameter-variation-in-different-vertical-regions-of-the-occipital-safe-donor-area
#2
Seon Sik Yun, Jae Hyun Park, Young Cheon Na
BACKGROUND: Little is known concerning hair diameter variation within the safe donor area for hair transplantation surgery. Thicker or thinner hair may be needed, depending on the recipient area, hairline design, and the purpose of surgery. METHODS: Twenty-seven patients (7 men and 20 women; mean age, 28 years; range, 20-47 years) were included in this study. The midoccipital point was used as the reference point on the horizontal plane at the upper border of the helical rim...
July 2017: Archives of Plastic Surgery
https://www.readbyqxmd.com/read/28728320/temple-and-postauricular-dissection-in-face-and-neck-lift-surgery
#3
Joo Heon Lee, Tae Suk Oh, Sung Wan Park, Jae Hoon Kim, Tanvaa Tansatit
Periauricular paresthesia may afflict patients for a significant amount of time after facelift surgery. When performing face and neck lift surgery, temple and posterior auricular flap dissection is undertaken directly over the auriculotemporal, great auricular, and lesser occipital nerve territory, leading to potential damage to the nerve. The auriculotemporal nerve remains under the thin outer superficial fascia just below the subfollicular level in the prehelical area. To prevent damage to the auriculotemporal nerve and to protect the temporal hair follicle, the dissection plane should be kept just above the thin fascia covering the auriculotemporal nerve...
July 2017: Archives of Plastic Surgery
https://www.readbyqxmd.com/read/28727603/nodular-lesion-in-cheek-with-a-hair-tuft
#4
David Ayala, Inés Escandell, Jose M Martin
Trichostasis spinulosa is a rarely diagnosed disorder of the pilosebaceous unit, characterized by retention of telogen hairs within the dilated follicles. A hair tuft can be seen protruding from the follicles. We present a case of trichostasis spinulosa associated with intradermal melanocytic nevi, where dermoscopy helps to identify this entity.
August 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28727600/nodular-lesion-in-cheek-with-a-hair-tuft
#5
David Ayala, Inés Escandell, Jose M Martín
No abstract text is available yet for this article.
August 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28727410/exosomes-mediate-epithelium-mesenchyme-crosstalk-in-organ-development
#6
Nan Jiang, Lusai Xiang, Ling He, Guodong Yang, Jinxuan Zheng, Chenglin Wang, Yimei Zhang, Sainan Wang, Yue Zhou, Tzong-Jen Sheu, Jiaqian Wu, Kenian Chen, Paulo G Coelho, Nicky M Tovar, Shin Hye Kim, Mo Chen, Yan-Heng Zhou, Jeremy J Mao
Organ development requires complex signaling by cells in different tissues. Epithelium and mesenchyme interactions are crucial for the development of the skin, hair follicles, kidney, lungs, prostate, major glands and the teeth. Despite myriad literature on cell-cell interactions and ligand-receptor binding, the roles extracellular vesicles in epithelium-mesenchyme interactions during organogenesis are poorly understood. Here, we discovered that ~100 nm exosomes were secreted by the epithelium and mesenchyme of a developing tooth organ, and diffused through the basement membrane...
July 20, 2017: ACS Nano
https://www.readbyqxmd.com/read/28727097/evaluating-the-impact-of-breed-pregnancy-and-hair-coat-on-body-temperature-and-sweating-rate-of-hair-sheep-ewes-in-the-tropics
#7
R W Godfrey, W D Preston, S R Joseph, L LaPlace, P E Hillman, K G Gebremedhin, C N Lee, R J Collier
The objective of this study was to evaluate the effect of pregnancy, breed, and hair coat on body temperature and sweating rate (SR) of hair sheep. St. Croix White (STX; = 9) and Dorper × STX (DRPX; = 9) ewes (3.6 yr of age) were evaluated over 4 d at 126 d of gestation (PREG) and over 4 d at 46 d postpartum (OPEN) in the shade and sun and in the morning (AM; 0900 to 1200 h) and afternoon (PM; 1300 to 1600 h) after a 20 min acclimation to each condition on each day. Data loggers recorded vaginal temperature (VT) at 10-min intervals for 96 h...
July 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/28727005/rapid-communication-generation-of-fgf5-knockout-sheep-via-the-crispr-cas9-system
#8
R Hu, Z Y Fan, B Y Wang, S L Deng, X S Zhang, J L Zhang, H B Han, Z X Lian
Sheep are an important source of fiber production. Fibroblast growth factor 5 (FGF5) is a dominant inhibitor of length of the anagen phase of the hair cycle. Knockout or silencing of the gene results in a wooly coat in mice, donkeys, dogs, and rabbits. In sheep breeding, wool length is one of the most important wool quality traits. However, traditional breeding cannot accurately and efficiently mediate an advanced genotype into the sheep genome. In this study, we generated 3 knockout sheep via the 1-step clustered regularly interspaced short palindromic repeat (CRISPR)/Cas9 system...
May 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/28726326/speechless
#9
Nadine T Himelfarb
Bright blue eyes rimmed with deep sun wrinkles, a crown of mousy brown hair that appeared freshly cut by a four-year old with safety scissors, the patient was thin figured, wearing a flannel, yellowed t-shirt peaking from underneath, and a boxy, heavily stained canvas jacket over the shoulders. Old jeans were cinched at the waist by a crackled leather belt. The dirty right foot which lay bare on the stretcher was then thrust at me. The patient pointed angrily at the exposed foot. This article is protected by copyright...
July 20, 2017: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/28726311/gaba-histamine-and-fmrfamide-immunoreactivity-in-the-visual-vestibular-and-central-nervous-systems-of-hermissenda-crassicornis
#10
Marissa P Webber, James W S Thomson, Johnny Buckland-Nicks, Roger P Croll, Russell C Wyeth
Hermissenda crassicornis is a model for studying the molecular and cellular basis for classical conditioning, based on its ability to associate light with vestibular stimulation. We used confocal microscopy to map histamine, FMRF-amide, and GABA immunoreactivity in the central nervous system (CNS), eyes, optic ganglia and statocysts of the nudibranchs. For histamine immunoreactivity, we documented both consistently and variably labelled CNS structures across individuals. We also noted minor differences in GABA immunoreactivity in the CNS compared to previous work on Hermissenda...
July 20, 2017: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/28726071/the-legend-of-medusa-with-snake-hair-in-didymaion-in-didyma-turkey
#11
EDITORIAL
Ali Çağlar Turgut, Yaşar Barış Turgut, Mehmet Turgut
No abstract text is available yet for this article.
July 19, 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/28725654/stem-cells-from-human-hair-follicles-first-mechanical-isolation-for-immediate-autologous-clinical-use-in-androgenetic-alopecia-and-hair-loss
#12
Pietro Gentile, Maria G Scioli, Alessandra Bielli, Augusto Orlandi, Valerio Cervelli
BACKGROUND: Hair follicles are known to contain a well-characterized niche for adult stem cells: the bulge, which contains epithelial and melanocytic stem cells. Stem cells in the hair bulge, a clearly demarcated structure within the lower permanent portion of hair follicles, can generate the interfollicular epidermis, hair follicle structures, and sebaceous glands. The bulge epithelial stem cells can also reconstitute in an artificial in vivo system to a new hair follicle. METHODS: In this study, we have developed a new method to isolate human adult stem cells by mechanical centrifugation of punch biopsy from human hair follicles without culture condition...
2017: Stem Cell Investigation
https://www.readbyqxmd.com/read/28725240/appraisal-of-testicular-volumes-volumes-matching-ultrasound-values-referenced-to-stages-of-genital-development
#13
Juan F Sotos, Naomi J Tokar
BACKGROUND: Testicular volumes obtained with orchidometers or external linear measurements in the scrotum (centimeter ruler or calipers) grossly over-estimate ultrasound volumes, have much variability and may not be accurate or reproducible. The reference of the values obtained by orchidometers or US, to age or Tanner stages is not useful to determine the normal values for stages of puberty, because overlapping of ages and values. Pubertal development is determined by two events, genital and pubic hair development, that should be analyzed independently because one could be out of step with the other...
2017: International Journal of Pediatric Endocrinology
https://www.readbyqxmd.com/read/28725177/characterization-of-lgr5-progenitor-cell-transcriptomes-after-neomycin-injury-in-the-neonatal-mouse-cochlea
#14
Shasha Zhang, Yuan Zhang, Pengfei Yu, Yao Hu, Han Zhou, Lingna Guo, Xiaochen Xu, Xiaocheng Zhu, Muhammad Waqas, Jieyu Qi, Xiaoli Zhang, Yan Liu, Fangyi Chen, Mingliang Tang, Xiaoyun Qian, Haibo Shi, Xia Gao, Renjie Chai
Lgr5+ supporting cells (SCs) are enriched hair cell (HC) progenitors in the cochlea. Both in vitro and in vivo studies have shown that HC injury can spontaneously activate Lgr5+ progenitors to regenerate HCs in the neonatal mouse cochlea. Promoting HC regeneration requires the understanding of the mechanism of HC regeneration, and this requires knowledge of the key genes involved in HC injury-induced self-repair responses that promote the proliferation and differentiation of Lgr5+ progenitors. Here, as expected, we found that neomycin-treated Lgr5+ progenitors (NLPs) had significantly greater HC regeneration ability, and greater but not significant proliferation ability compared to untreated Lgr5+ progenitors (ULPs) in response to neomycin exposure...
2017: Frontiers in Molecular Neuroscience
https://www.readbyqxmd.com/read/28723343/%C3%AE-catenin-is-involved-in-oleanolic-acid-dependent-promotion-of-proliferation-in-human-hair-matrix-cells-in-an-in-vitro-organ-culture-model
#15
Ben Liu, Xianyan Chen, Huan Yi, Le Han, Bin Ji, Haiyan Chen, Wenjia Deng, Miaojian Wan
Oleanolic acid (OA), a pentacyclic triterpenoid compound which can be found in >1600 plants, has been shown to promote hair growth. To study the mechanisms of OA on hair growth, we investigated hair follicle (HF) growth on four different concentration OA using human hair follicle organ culture model. We found that HFs treated with 1 or 10μg/mL OA showed statistically enhanced elongation of the hair shaft and anagen-like stage. Moreover, higher positive rate of Ki-67, a matrix cellular marker of proliferation, was detected in the same groups treated with 1 or 10μg/mL than those treated with vehicle...
July 16, 2017: Fitoterapia
https://www.readbyqxmd.com/read/28722460/-psychological-consequences-of-hair-loss
#16
Zora Dubská
Hair plays an important role in human life. Quantitative or qualitative changes of hair are therefore perceived unfavorably. The psychological consequences of hair loss are described in both androgenic alopecia and alopecia areata. Alopecia areata should be distinguished from other diagnostic units such as trichotillomania. The issue of hair disease requires a multidisciplinary collaboration, in which the dermatologist has a key role to play.
2017: Casopís Lékar̆ů C̆eských
https://www.readbyqxmd.com/read/28722458/-androgenetic-alopecia-in-women
#17
Jana Krabcová
Androgenetic alopecia is one of the most common diagnoses in a hair clinic. It is non-scarring pattern hair losses that affect individuals, independent on severity, age and gender. The incidence of AGA increases within the age. AGA affects women less frequently, is usually milder and is associated with diffuse thinning of the hair scalp. Prompt diagnosis and treatment are essential for obtaining optimal outcome.
2017: Casopís Lékar̆ů C̆eských
https://www.readbyqxmd.com/read/28722457/-diseases-affecting-the-scalp
#18
Dana Suchánková
The skin of the scalp differs from the skin on the other areas of the body because of a higher density of hair follicles and higher sebum production. These, together with the presence of hair, provide a suitable environment for superficial infections, infestations and inflammatory diseases. The good condition of the scalp has a significant impact on the patient's mental well-being and social interaction. The visibility of this part of the skin and the presence of hair itself restrict the range of possible therapeutic agents that can be used due to the complicated application and poor cosmetic outcome...
2017: Casopís Lékar̆ů C̆eských
https://www.readbyqxmd.com/read/28722456/-hirsutism-etiopathogenesis-diagnostics-and-treatment
#19
Jiří Ettler
Hirsutism is defined as excessive terminal hair growth in distribution typical for postpubertal men. It affects approximately 5-10 % of women and most frequently manifests in puberty. Significant cosmetic stigmatization is the usual complaint that brings patient to the doctor and it is crucial to always rule out any primary underlying disease causing hirsutism - benign or malignant. In this review etiopathogenesis, diagnostic procedures and treatment options are discussed.
2017: Casopís Lékar̆ů C̆eských
https://www.readbyqxmd.com/read/28722455/-hidradenitis-suppurativa-symptoms-diagnostics-and-therapy
#20
Monika Arenbergerová, Robert Artur Dahmen, Petr Arenberger
Hidradenitis suppurativa is a chronic skin disorder characterized by recurrent inflammatory nodules, fistulas, abscesses, and scarring mainly in the intertriginous areas with terminal hair and apocrine glands. Hidradenitis suppurativa manifests usually after puberty, in the third life decade and persists for many years. The prevalence of the disease is estimated to be 0,5 % in the Czech Republic. Women are most often affected in the axillary and inguinal parts, while men in the perianal and gluteal areas. The exact pathogenesis is still unknown...
2017: Casopís Lékar̆ů C̆eských
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