keyword
MENU ▼
Read by QxMD icon Read
search

Physical therapy

keyword
https://www.readbyqxmd.com/read/29792380/alirocumab-as-add-on-therapy-to-statins-current-evidence-and-clinical-potential
#1
Johann Auer, Robert Berent
Atherosclerotic cardiovascular diseases (ASCVDs) are associated with a substantial mortality, physical morbidity, and mental disability. Elevated plasma low-density lipoprotein cholesterol (LDL-C) levels play a major role in the pathophysiology of ASCVDs. Statins have been shown to reduce ASCVD risk and associated events and are recommended as first-line therapy for treatment of hypercholesterolemia by current international guidelines. The key issue is to attain guideline-recommended LDL-C levels (below 70 mg/dl) for patients at very high cardiovascular risk...
May 1, 2018: Therapeutic Advances in Cardiovascular Disease
https://www.readbyqxmd.com/read/29792106/psychometric-properties-of-the-photograph-series-of-daily-activities-short-electronic-version-phoda-sev-in-patients-with-chronic-low-back-pain-according-to-cosmin-checklist
#2
Crystian Bitencourt Oliveira, Marcia Rodrigues Franco, Samantha Janaina Demarchi, Rob Johannes E M Smeets, Ivan P J Huijnen, Priscila Kalil Morelhão, Thalysi Mayumi Hisamatsu, Rafael Zambelli Pinto
Study Design A prospective cohort study. Background The Photograph Daily Activities Series - Short Electronic Version (PHODA-SeV) assesses perceived harmfulness of daily activities in patients with low back pain (LBP). Although there is some evidence that the PHODA-SeV is a reliable and valid tool, its psychometric properties have not been fully investigated. Objectives To investigate the test-retest reliability, measurement error, interpretability, construct validity, internal and external responsiveness of the PHODA-SeV in patients with chronic LBP...
May 23, 2018: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/29791829/burosumab-therapy-in-children-with-x-linked-hypophosphatemia
#3
Thomas O Carpenter, Michael P Whyte, Erik A Imel, Annemieke M Boot, Wolfgang Högler, Agnès Linglart, Raja Padidela, William Van't Hoff, Meng Mao, Chao-Yin Chen, Alison Skrinar, Emil Kakkis, Javier San Martin, Anthony A Portale
BACKGROUND: X-linked hypophosphatemia is characterized by increased secretion of fibroblast growth factor 23 (FGF-23), which leads to hypophosphatemia and consequently rickets, osteomalacia, and skeletal deformities. We investigated burosumab, a monoclonal antibody that targets FGF-23, in patients with X-linked hypophosphatemia. METHODS: In an open-label, phase 2 trial, we randomly assigned 52 children with X-linked hypophosphatemia, in a 1:1 ratio, to receive subcutaneous burosumab either every 2 weeks or every 4 weeks; the dose was adjusted to achieve a serum phosphorus level at the low end of the normal range...
May 24, 2018: New England Journal of Medicine
https://www.readbyqxmd.com/read/29791704/use-of-neuromuscular-electrical-stimulation-during-physical-therapy-may-reduce-the-incidence-of-arthrofibrosis-after-total-knee-arthroplasty
#4
Chukwuweike U Gwam, Tanner McGinnis, Jennifer I Etcheson, Nicole E George, Assem A Sultan, Ronald E Delanois, Anil Bhave, Steven F Harwin, Michael A Mont
INTRODUCTION: Arthrofibrosis remains a major complication following total knee arthroplasty (TKA) that negatively impacts patient outcomes and exhausts healthcare resources. The use of neuromuscular electrical stimulation (NMES) has demonstrated the ability to facilitate quadriceps muscle recovery and reduce pain. Therefore, the purpose of this study was to compare TKA patients who received physical therapy (PT) and adjuvant NMES therapy versus physical therapy alone in terms of: 1) rates of manipulation under anesthesia (MUA) to treat arthrofibrosis; and 2) post-therapy range of motion (ROM)...
June 1, 2018: Surgical Technology International
https://www.readbyqxmd.com/read/29791651/relationship-between-adiponectin-and-leptin-on-osteocalcin-in-obese-adolescents-during-weight-loss-therapy
#5
Raquel Munhoz da Silveira Campos, Deborah Cristina Landi Masquio, Flávia Campos Corgosinho, Joana Pereira de Carvalho-Ferreira, Bárbara Dal Molin Netto, Ana Paula Grotti Clemente, Lian Tock, Sergio Tufik, Marco Túlio de Mello, Ana Raimunda Dâmaso
OBJECTIVES: Obesity is a multifactorial disease characterized by the presence of the pro-inflammatory state associated with the development of many comorbidities, including bone turnover marker alterations. This study aimed to investigate the role of the inflammatory state on bone turnover markers in obese adolescents undergoing interdisciplinary weight loss treatment for one year. SUBJECTS AND METHODS: Thirty four post-pubescent obese adolescents with primary obesity, a body mass index (BMI) greater than > 95th percentile of the CDC reference growth charts, participated in the present investigation...
May 17, 2018: Archives of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29790404/clinical-and-neurophysiological-changes-after-targeted-intrathecal-injections-of-bone-marrow-stem-cells-in-a-c3-tetraplegic-subject
#6
Andrea Jimena Santamaria, Francisco D Benavides, Darcy L DiFede, Aisha Khan, Marietsy V Pujol, W Dalton Dietrich, Antonio Marttos, Barth A Green, Joshua M Hare, James Guest
High-level quadriplegia is a devastating condition with limited treatment options. Bone marrow derived stem cells (BMSCs) are reported to have immunomodulatory and neurotrophic effects in spinal cord injury (SCI). We report a subject with complete C2 SCI who received 3 anatomically targeted intrathecal infusions of BMSCs under a single-patient expanded access IND. She underwent intensive physical therapy and was followed for over 2 years. At end-point, her AIS grade improved from A to B and she recovered focal pressure touch sensation over several body areas...
May 23, 2018: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29790354/-opioids-and-new-trends-in-pain-therapy
#7
Jan Lejčko
Opioids are well known for their ability to reduce the perception of pain without a loss of consciousness. However, the influence of opioids on organism is very complex. Clinical pharmacology of currently available opioid analgesics is determined by three major factors - their opioid receptor properties, pharmacokinetic properties and genetic polymorphism in the opiate receptor and cytochrome P450 isoform. In acute severe pain are opioids very efficient. Long-term experience with opioid analgesia in patients with cancer pain has shown high favorable risk/benefit ratio...
2018: Casopís Lékar̆ů C̆eských
https://www.readbyqxmd.com/read/29790196/rituximab-is-ineffective-for-treatment-of-fatigue-in-primary-biliary-cholangitis-a-phase-2-randomised-controlled-trial
#8
Amardeep Khanna, Laura Jopson, Denise Howel, Andrew Bryant, Andrew Blamire, Julia L Newton, David E Jones
Primary Biliary Cholangitis (PBC) is a chronic cholestatic liver disease. Half of patients experience debilitating fatigue which is currently untreatable. Previous studies have shown muscle bioenergetic abnormalities in PBC, including increased muscle acidosis with exercise linked to the anti-mitochondrial antibody (AMA) diagnostic of the disease, and reduced anaerobic threshold. In this study we addressed the hypothesis that fatigue in PBC is driven by muscle bioenergetic abnormality related to AMA, and that AMA reduction with B-cell depletion therapy will improve fatigue...
May 23, 2018: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/29790166/physical-therapy-as-the-first-point-of-care-to-treat-low-back-pain-an-instrumental-variables-approach-to-estimate-impact-on-opioid-prescription-health-care-utilization-and-costs
#9
Bianca K Frogner, Kenneth Harwood, C Holly A Andrilla, Malaika Schwartz, Jesse M Pines
OBJECTIVE: To compare differences in opioid prescription, health care utilization, and costs among patients with low back pain (LBP) who saw a physical therapist (PT) at the first point of care, at any time during the episode or not at all. DATA SOURCES: Commercial health insurance claims data, 2009-2013. STUDY DESIGN: Retrospective analyses using two-stage residual inclusion instrumental variable models to estimate rates for opioid prescriptions, imaging services, emergency department visits, hospitalization, and health care costs...
May 23, 2018: Health Services Research
https://www.readbyqxmd.com/read/29789969/identification-of-risk-factors-for-toxicity-in-patients-with-hormone-receptor-positive-advanced-breast-cancer-treated-with-bevacizumab-plus-letrozole-a-calgb-40503-alliance-correlative-study
#10
Daneng Li, Linda M McCall, Olwen M Hahn, Clifford A Hudis, Harvey J Cohen, Hyman B Muss, Aminah Jatoi, Jacqueline M Lafky, Karla V Ballman, Eric P Winer, Debu Tripathy, Bryan Schneider, William Barry, Maura N Dickler, Arti Hurria
BACKGROUND: In hormone receptor-positive advanced breast cancer, a progression-free survival benefit was reported with addition of bevacizumab to first-line letrozole. However, increased toxicity was observed. We hypothesized that functional age measures could be used to identify patients at risk for toxicity while receiving letrozole plus bevacizumab for hormone receptor-positive advanced breast cancer. METHODS: CALGB 40503 was a phase III trial that enrolled patients with hormone receptor-positive advanced breast cancer randomized to letrozole with or without bevacizumab...
May 22, 2018: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/29789217/outcomes-and-cost-of-open-versus-endovascular-repair-of-intact-thoracoabdominal-aortic-aneurysm
#11
Satinderjit Locham, Hanaa Dakour-Aridi, Besma Nejim, Jasninder Dhaliwal, Widian Alshwaily, Mahmoud Malas
OBJECTIVE: Many previous studies have evaluated the outcomes of open and endovascular repair of thoracoabdominal aortic aneurysms (TAAAs). However, little is known about the differences in cost of these procedures and the potential factors driving these differences. The aim of this study was to evaluate the outcomes and cost of open aortic repair (OAR) vs endovascular repair of intact TAAA. METHODS: All patients undergoing repair for intact TAAA were identified in the Premier Healthcare Database (July 2009-March 2015)...
May 19, 2018: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29788886/novel-pharmacotherapeutic-approaches-in-treatment-of-alcohol-addiction
#12
Rashidi Mohamed Pakri Mohamad, Jaya Kumar, Shihab Udin Ahmad, Isa Naina Mohamed
In the past two decades, the search for novel pharmacotherapies to treat alcohol addiction been a global endeavour. This has resulted in several drugs that have been approved and successfully marketed for public use while some are still in the testing phase. These pharmacological agents, though effective for the treatment of alcoholism, are not without shortcomings; such as abuse potential, serious mental and physical adverse effects, interaction with alcohol and also poor metabolism and excretion. As more is being understood about the neurobiology of alcohol addiction as well as the unique pharmacological action of these drugs, new agents are evaluated for potential benefits when used as a adjunct in combination therapy...
May 22, 2018: Current Drug Targets
https://www.readbyqxmd.com/read/29788876/exploiting-significance-of-physical-exercise-in-prevention-of-gastrointestinal-disorders
#13
Jan Bilski, Agnieszka Mazur-Bialy, Marcin Magierowski, Slawomir Kwiecien, Dagmara Wojcik, Agata Ptak-Belowska, Marcin Surmiak, Aneta Targosz, Katarzyna Magierowska, Tomasz Brzozowski
BACKGROUND: Physical activity can be involved in the prevention of gastrointestinal (GI)-tract diseases, however, the results regarding the volume and the intensity of exercise considered as beneficial for protection of gastrointestinal organs are conflicting. AIMS AND METHODS: The main objective of this review is to provide a comprehensive and updated overview on the beneficial and harmful effects of physical activity on the gastrointestinal tract. We attempted to discuss recent evidence regarding the association between different modes and intensity levels of exercise and physiological functions of the gut and gut pathology...
May 21, 2018: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/29788851/-micturition-complaints-in-men-one-symptom-multiple-causes
#14
Stefanie Cermak, Scott Putman
Micturition Complaints in Men: One Symptom, Multiple Causes Abstract. Micturition complaints in male patients are a common problem in the general practice. The complaints are summarized as lower urinary tract symptoms (LUTS) and are often an expression of prostate enlargement and the resulting bladder outlet -obstruction. Differential diagnosis has to exclude prostate-related LUTS. Basic diagnostics are performed by means of detailed physical history, Combur test and ultrasound. The most common diagnoses can already be made at this point and therapy can be initiated...
2018: Praxis
https://www.readbyqxmd.com/read/29788412/treatment-of-mal-de-debarquement-syndrome-in-a-deployed-environment
#15
Stephanie M Schenk, Jacklyn M Wagner, Jarrod A Miller, Tracey M Lyons-White, Emilee C Venn, Michael D April, Brit Long, Steven G Schauer, Joshua J Oliver
We report the case of a 26-year-old Caucasian female with persistent sensations of forward and reverse movement with spontaneous onset. This worsened over 4 wk. The patient reported an episode of these symptoms 5 mo prior, which lasted for 3 mo before improving. Our case details the treatment of Mal de Debarquement syndrome, or Disembarkment Syndrome, in a deployed military environment. Mal de Debarquement was a term originally coined to describe the persistent sensation of rocking back and forth after disembarking a boat and returning to land...
May 18, 2018: Military Medicine
https://www.readbyqxmd.com/read/29788253/effectiveness-of-a-blended-physical-therapist-intervention-in-people-with-hip-osteoarthritis-knee-osteoarthritis-or-both-a-cluster-randomized-controlled-trial
#16
Corelien J J Kloek, Daniël Bossen, Peter M Spreeuwenberg, Joost Dekker, Dinny H de Bakker, Cindy Veenhof
Background: Integrating physical therapy sessions and an online application (e-Exercise) might support people with hip osteoarthritis (OA), knee OA, or both (hip/knee OA) in taking an active role in the management of their chronic condition and may reduce the number of physical therapy sessions. Objective: The objective of this study was to investigate the short- and long-term effectiveness of e-Exercise compared to usual physical therapy in people with hip/knee OA...
May 17, 2018: Physical Therapy
https://www.readbyqxmd.com/read/29788083/evaluation-of-an-intensive-interdisciplinary-pain-treatment-based-on-acceptance-and-commitment-therapy-for-adolescents-with-chronic-pain-and-their-parents-a-nonrandomized-clinical-trial
#17
Mike K Kemani, Marie Kanstrup, Abbie Jordan, Line Caes, Jeremy Gauntlett-Gilbert
Objective: Parental factors are central in the development and maintenance of chronic pain in youths. Only a handful of studies have investigated the impact of psychological treatments for pediatric chronic pain on parental factors, and the relationships between changes in parental and adolescent factors. In the current study, we evaluated the effects of an intensive interdisciplinary pain treatment (IIPT) program based on Acceptance and Commitment Therapy (ACT) for adolescents with chronic pain, on adolescent and parental variables, and the relationship between parental psychological flexibility and adolescent pain acceptance...
May 17, 2018: Journal of Pediatric Psychology
https://www.readbyqxmd.com/read/29787832/a-comparative-study-of-quality-of-life-functional-and-bone-outcomes-in-osteogenesis-imperfecta-with-bisphosphonate-therapy-initiated-in-childhood-or-adulthood
#18
Andrew G Feehan, Margaret R Zacharin, Angelina S Lim, Peter J Simm
Bisphosphonates have been used for treatment of bone fragility disorders for over 25 years to increase bone mineral density (BMD). Anecdotally, bisphosphonate-treated Osteogenesis Imperfecta (OI) has a different trajectory to the natural history of untreated OI in terms of fracture incidence, quality of life and physical function, with minimal published evidence to support this clinical observation. This study describes functional outcomes of a cohort of adults with OI, stratified according to severity and treated with intravenous bisphosphonates as children...
May 19, 2018: Bone
https://www.readbyqxmd.com/read/29787697/rehabilitation-practice-patterns-following-anterior-cruciate-ligament-reconstruction-a-survey-of-physical-therapists
#19
Elliot M Greenberg, Eric T Greenberg, Jeffrey Albaugh, Eileen Storey, Theodore J Ganley
Study Design Cross-sectional survey. Background Recovery from anterior cruciate ligament reconstruction (ACLR) requires an intensive course of post-operative rehabilitation. Although guidelines outlining evidence-based rehabilitation recommendations have been published, the actual practice patterns of physical therapists are unknown. Objectives To analyze the current landscape of clinical practice as it pertains to rehabilitation progression and the use of time and objective criteria following ACLR. Methods An online survey was distributed to members of the orthopaedics, sports and private practice sections of the American Physical Therapy Association (APTA) between January and March 2017...
May 22, 2018: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/29787696/impact-of-risk-adjustment-on-provider-ranking-for-patients-with-low-back-pain-receiving-physical-therapy
#20
Daniel Deutscher, Mark W Werneke, Deanna Hayes, Jerome E Mioduski, Karon F Cook, Julie Fritz, Linda J Woodhouse, Paul W Stratford
Study Design Retrospective cohort. Background Impact of risk-adjustment on clinic quality ranking for patients treated in physical therapy outpatient clinics is unknown. Objectives To compare clinic ranking, based on unadjusted vs. risk-adjusted outcomes, for patients with low back pain (LBP) treated in physical therapy. Methods Secondary analysis of data from adult patients with LBP treated in outpatient physical therapy clinics during 2014-2016. Patients with complete outcomes data at admission and discharge were included to develop the risk-adjustment model...
May 22, 2018: Journal of Orthopaedic and Sports Physical Therapy
keyword
keyword
1369
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"