Kistler-Fischbacher Melanie, Armbrecht Gabriele, Gängler Stephanie, Theiler Robert, Rizzoli Renè, Dawson-Hughes Bess, A Kanis John, C Hofbauer Lorenz, C Schimmer Ralph, Vellas Bruno, A P Da Silva José, Orav E John, W Kressig Reto, Egli Andreas, Lang Wei, A Wanner Guido, A Bischoff-Ferrari Heike
INTRODUCTION: Evidence on the effects of Vitamin D, omega-3 s and exercise on aBMD in healthy older adults is limited. We examined whether vitamin D3, omega-3 s, or a simple home-based exercise program (SHEP), alone or in combination, over three years, improve lumbar spine (LS), femoral neck (FN) or total hip (TH) aBMD assessed by DXA. METHODS: aBMD was a secondary outcome in DO-HEALTH, a 3-year, multicenter, double-blind, randomized 2 × 2 × 2 factorial design trial in generally healthy older adults age ≥ 70 years...
April 13, 2024: Journal of Bone and Mineral Research