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https://www.readbyqxmd.com/read/29679859/the-relationship-of-age-activity-and-body-size-on-osteoarthritis-in-weight-bearing-skeletal-regions
#1
Stephanie E Calce, Helen K Kurki, Darlene A Weston, Lisa Gould
This study examined the simultaneous impact of multiple underlying factors on OA expression in weight-bearing joints of the vertebrae and lower limb of a modern European skeletal sample (Lisbon and Sassari). OA was evaluated using standard ranked categorical scoring; composite OA scores derived through principal component analysis. Body size was calculated from postcranial measurements; torsional strength (J) of the femoral midshaft was calculated from three-dimensional surface models, size standardized and used as a proxy for activity...
April 18, 2018: International Journal of Paleopathology
https://www.readbyqxmd.com/read/29679732/inter-site-variability-of-the-osteocyte-lacunar-network-in-the-cortical-bone-underpins-fracture-susceptibility-of-the-superolateral-femoral-neck
#2
Tim Rolvien, Annika Vom Scheidt, Kilian Stockhausen, Petar Milovanovic, Danijela Djonic, Jan Hubert, Thelonius Hawellek, Alexander Wacker, Volker Jebens, Klaus Püschel, Elizabeth A Zimmermann, Marija Djuric, Michael Amling, Björn Busse
BACKGROUND: The osteocytic lacunar network is considered to be an integral player in the regulation of bone homeostasis, and reduction in osteocytes is associated with reduced bone strength. Here, we analyzed site-specific patterns in osteocyte characteristics and matrix composition in the cortical compartment of the femoral neck to reveal structural basis of its fragility. METHODS: Cross-sections of the human femoral neck - one of the most common fracture sites - were acquired from 12 female cadavers (age 34-86 years) and analyzed with backscattered scanning electron microscopy and high-resolution micro-computed tomography (μ-CT)...
April 18, 2018: Bone
https://www.readbyqxmd.com/read/29679731/changes-in-pediatric-dxa-measures-of-musculoskeletal-outcomes-and-correlation-with-quantitative-ct-following-treatment-of-acute-lymphoblastic-leukemia
#3
Sogol Mostoufi-Moab, Andrea Kelly, Jonathan A Mitchell, Joshua Baker, Babette S Zemel, Jill Brodsky, Jin Long, Mary B Leonard
We previously reported significant gains in pQCT measures of tibia trabecular bone mineral density (BMD) and cortical structure following completion of therapy in children and adolescents with acute lymphoblastic leukemia (ALL). The objective of this study was to examine changes in DXA measures used in clinical practice and expressed as Z-scores using robust national reference data. Children and adolescents, ages 5 to 18 years were enrolled within 2 (median 0.8) years of completing ALL therapy. DXA total-body less-head bone mineral content (TBLH-BMC), and spine, total hip, femoral neck, and 1/3rd radius areal BMD (aBMD) were assessed in 45 participants at enrollment and 12-months later...
April 18, 2018: Bone
https://www.readbyqxmd.com/read/29679683/is-distal-femoral-torsion-the-same-in-both-of-a-patient-s-legs-morphometric-ct-study
#4
J-S Beranger, D Dujardin, J-F Taburet, P Boisrenoult, C Steltzlen, P Beaufils, N Pujol
INTRODUCTION: The rotational position of the femoral component is a primary driver of success in total knee arthroplasty. However, distal femoral torsion (DFT) varies greatly between individuals. Measuring DFT preoperatively by CT in combination with computer-assisted surgery can significantly improve the rotational positioning of the femoral component. However, a preoperative CT scan is costly and exposes the patient to radiation. These are doubled when the patient is undergoing bilateral arthroplasty...
April 18, 2018: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/29679137/ten-versus-external-fixator-in-the-management-of-pediatric-diaphyseal-femoral-fractures-evaluation-of-the-outcomes
#5
Giuseppe Rollo, Pasquale Guida, Michele Bisaccia, Paolo Pichierri, Marco Filipponi, Riccardo Maria Lanzetti, Auro Caraffa, Alessandro Stasi, Valentina Russi, Domenico Lupariello, Luigi Meccariello
INTRODUCTION: Over the last 20 years, the incidence of pediatric diaphyseal femoral fractures was increased, due to changes in the children's daily activities. The healing times are different according to the chosen treatment and to other factors such as age, type of fracture, involvement of the soft tissues, and concomitance with other injuries. MATERIALS AND METHODS: From 2000 to 2015, 38 pediatric patients with diaphyseal femoral fractures were surgically treated and enrolled in the study...
April 20, 2018: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/29679117/the-infrapatellar-fat-pad-is-a-dynamic-and-mobile-structure-which-deforms-during-knee-motion-and-has-proximal-extensions-which-wrap-around-the-patella
#6
Joanna M Stephen, Ran Sopher, Sebastian Tullie, Andrew A Amis, Simon Ball, Andy Williams
PURPOSE: The infrapatellar fat pad (IFP) is a common cause of knee pain and loss of knee flexion and extension. However, its anatomy and behavior are not consistently defined. METHODS: Thirty-six unpaired fresh frozen knees (median age 34 years, range 21-68) were dissected, and IFP attachments and volume measured. The rectus femoris was elevated, suprapatellar pouch opened and videos recorded looking inferiorly along the femoral shaft at the IFP as the knee was flexed...
April 20, 2018: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29679110/correction-to-raman-spectroscopy-reveals-differences-in-molecular-structure-between-human-femoral-heads-affected-by-steroid-associated-and-alcohol-associated-osteonecrosis
#7
Ema Nakahara, Wenliang Zhu, Giuseppe Pezzotti, Hidetoshi Hamada, Masaki Takao, Takashi Sakai, Nobuhiko Sugano
The original publication of this paper contain an error for the first name and last name of the second author have been mixed up as "Wenliang, Z.".
April 19, 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29679108/fluorodeoxyglucose-positron-emission-tomography-imaging-for-diagnosing-periprosthetic-hip-infection-the-importance-of-diagnostic-criteria
#8
Steven J Verberne, Olivier P P Temmerman, Ben Hai Vuong, Pieter G Raijmakers
BACKGROUND: Fluorodeoxyglucose positron emission tomography (FDG-PET) is a novel method of assessing suspected periprosthetic hip infection. However, a heterogeneity of sensitivity and specificity using different diagnostic criteria across clinical studies has been published. The objective of this study is to evaluate the various diagnostic criteria using FDG-PET in diagnosing periprosthetic hip infection. METHODS: FDG-PET scans of patients suffering from painful hip prostheses between 2008 and 2015 were retrospectively reviewed...
April 20, 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29678650/femoseal%C3%A2-device-use-for-femoral-artery-closure-by-different-techniques
#9
Roberto Gabrielli, Maria Sofia Rosati, Massiliano Millarelli, Angelica Dante, Maurizio Maiorano, Aldo Musilli, Roberto Chiappa, Marco Ventura
BACKGROUND: Common femoral artery is still the most frequently site used for vascular access, mostly for peripheral arterial interventions and its puncture remains a significant source of patient's morbidity. Manual compression (MC) has been the gold standard for hemostasis after femoral catheterization until recently, but only in the last few years, vascular closure devices (VCDs) are replacing MC due to their rapid development. Nowadays also vascular surgeons are becoming familiar with VCDs...
April 17, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29678647/post-mortem-retrieval-of-arterial-allografts-preliminary-results
#10
Dorian Verscheure, Julien Gaudric, Jérémie Jayet, Philippe Tresson, Mohamed Jarraya, Pierre Julia, Marc Coggia, Laurent Chiche, Fabien Koskas
OBJECTIVES: Cryopreserved arterial allografts are vascular substitutes used for arterial reconstructions in a septic field. Their use remains however limited by the shortage of donors. One of the possibilities to address this lack of grafts is to multiply the sources of retrieval. The objective of this preliminary study was the evaluation of the early clinical results and the microbiological safety of arterial grafts retrieved after death. MATERIAL AND METHODS: In addition to the standard conditions of arterial sampling the criteria of inclusion for postmortem retrieval comprised the refrigeration of the body of the donor within four hours following the death, a 24-hour time limit from the death, and the availability of an adapted place for retrieval (surgical unit or death chamber respecting the required aseptic conditions)...
April 17, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29678393/positive-correlations-between-free-vitamin-d-and-bone-variables-in-a-group-of-young-lebanese-women
#11
Abir Alwan, Maroun Rizkallah, Ghassan Maalouf, Joseph Matta, Fabienne Frenn, Angélique Barakat, Falah Bachour, Amer Sebaaly, Abdel-Jalil Berro, Nathalie Al Rassy, Mirza Howayek, Hassane Zouhal, Rawad El Hage
Optimizing bone mass in adulthood is of great importance to prevent the occurrence of osteoporosis in later age. Vitamin D is an essential component of bone health. Low-serum vitamin D is associated with low bone mineral density (BMD), which is an important predictor of fracture risk. However, most cells, apart from renal tubular cells, are exposed to free rather than to total 25-hydroxyvitamin D. Whether free vitamin D would be a better marker than total vitamin D is still under debate. The aim of the present study was to explore the relationships between serum total vitamin D, vitamin D-binding protein (BP), free vitamin D, and bone parameters in a group of young Lebanese women...
March 26, 2018: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/29678170/self-reported-functional-recovery-after-reconstruction-versus-repair-in-acute-anterior-cruciate-ligament-rupture-rotor-a-randomized-controlled-clinical-trial
#12
Barbara C Boer, Roy A G Hoogeslag, Reinoud W Brouwer, Anna Demmer, Rianne M H A Huis In 't Veld
BACKGROUND: Anterior cruciate ligament (ACL) reconstruction is today's surgical gold standard for ACL rupture. Although it provides satisfactory results, not all patients return to their previous activity level and moreover, early posttraumatic osteoarthritis is not prevented. As such, a renewed interest has emerged in ACL suture repair combined with dynamic augmentation. Compared to ACL reconstruction, the hypothesized advantages of ACL suture repair are earlier return to sports, reduction of early posttraumatic osteoarthritis and preservation of the patient's native ACL tissue and proprioceptive envelope of the knee...
April 20, 2018: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29677465/the-effect-of-sex-menstrual-cycle-phase-and-monophasic-oral-contraceptive-pill-use-on-local-and-central-arterial-stiffness-in-young-adults
#13
Stacey E Priest, Ninette Shenouda, Maureen J MacDonald
Arterial stiffness is associated with increased cardiovascular disease risk. Previous sex-based investigations of local and central stiffness report inconsistent findings and have not controlled for menstrual cycle phase in women. There is also evidence that sex hormones influence the vasculature, but their impact on arterial stiffness across a natural menstrual (NAT) or oral contraceptive pill (OCP) cycle has been understudied. This study sought to 1) examine potential sex differences in local and central stiffness, 2) compare stiffness profiles between NAT and OCP cycles, and 3) investigate the relationship between duration of OCP use and arterial stiffness...
April 20, 2018: American Journal of Physiology. Heart and Circulatory Physiology
https://www.readbyqxmd.com/read/29677091/factors-associated-with-revision-surgery-after-internal-fixation-of-hip-fractures
#14
Sheila Sprague, Emil H Schemitsch, Marc Swiontkowski, Gregory J Della Rocca, Kyle J Jeray, Susan Liew, Gerard P Slobogean, Sofia Bzovsky, Diane Heels-Ansdell, Qi Zhou, Mohit Bhandari
BACKGROUND: Femoral neck fractures are associated with high rates of revision surgery after management with internal fixation. Using data from the Fixation using Alternative Implants for the Treatment of Hip fractures (FAITH) trial evaluating methods of internal fixation in patients with femoral neck fractures, we investigated associations between baseline and surgical factors and the need for revision surgery to promote healing, relieve pain, treat infection or improve function over 24 months postsurgery...
May 2018: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/29677054/effects-of-acute-aerobic-exercise-on-arterial-stiffness-and-cerebrovascular-pulsatility-in-adults-with-and-without-hypertension
#15
Wesley K Lefferts, Jacob P DeBlois, Candace N Receno, Tiago V Barreira, Tom D Brutsaert, Robert L Carhart, Kevin S Heffernan
OBJECTIVES: Stiffer central arteries, as seen in hypertension (HTN), foster transmission of pulsatile hemodynamics into fragile cerebral vessels. Aerobic exercise is recommended for adults with HTN, but its effects on arterial stiffness and pulsatility in this group are unclear. This study sought to investigate the effect of acute aerobic exercise on arterial stiffness and cerebrovascular pulsatility in 30 adults with treated HTN and 30 age, sex, and BMI-matched adults without HTN (56 ± 6 years, BMI 28...
April 19, 2018: Journal of Hypertension
https://www.readbyqxmd.com/read/29676968/effects-of-daily-intake-of-calcium-and-vitamin-d-enriched-milk-in-healthy-postmenopausal-women-a-randomized-controlled-double-blind-nutritional-study
#16
Rebeca Reyes-Garcia, Nicolas Mendoza, Santiago Palacios, Nancy Salas, Miguel Quesada-Charneco, Antonia Garcia-Martin, Juristo Fonolla, Federico Lara-Villoslada, Manuel Muñoz-Torres
OBJECTIVE: To determine the effect of the daily intake of calcium and vitamin D-enriched milk (with or without fructooligosaccharides [FOS]) on vitamin D, bone metabolism, and cardiovascular risk factors. MATERIALS AND METHODS: Two-year randomized controlled study, including 500 healthy postmenopausal women, assigned to 500 mL/day of skimmed milk to one of three groups: Low-dose (L): (120 mg/100 mL calcium, vitamin D3 30 UI/100 mL), group A: calcium and vitamin D (180 mg/100 mL and 120 UI/100 mL), and group B: calcium and vitamin D (180 mg/100 mL and 120 UI/100 mL) and FOS (5 g/L)...
April 20, 2018: Journal of Women's Health
https://www.readbyqxmd.com/read/29676206/fabrication-of-vascularized-bone-flaps-with-sustained-release-of-rhbmp-2-and-arteriovenous-bundle
#17
Bo Li, Changshun Ruan, Yufei Ma, Zhifeng Huang, Zhenfei Huang, Gang Zhou, Jing Zhang, Hai Wang, Zhihong Wu, Guixing Qiu
INTRODUCTION: It is a common treatment strategy in the clinic to transplant a vascularized bone flap for a large bone defect. But it is difficult for peripheral blood vessels to grow into the central region of a large bone construct. In this study, we fabricated a vascularized bone flap from a 3D-printed biodegradable PLGA/β-TCP scaffold using the combination of an arteriovenous (AV) bundle and recombinant human bone morphogenetic protein-2 (rhBMP-2). MATERIALS AND METHODS: A degradable porous poly (lactide-co-glycolide) /-tri-calcium phosphate (PLGA/β-TCP) scaffold was prepared by adopting 3D plotting and a low-temperature deposition technique...
April 20, 2018: Tissue Engineering. Part A
https://www.readbyqxmd.com/read/29676169/thirty-minutes-of-running-exercise-decreases-t2-signal-intensity-but-not-thickness-of-the-knee-joint-cartilage-a-3-0-t-magnetic-resonance-imaging-study
#18
Yiğitcan Karanfil, Naila Babayeva, Gürhan Dönmez, H Barış Diren, Muzaffer Eryılmaz, Mahmut Nedim Doral, Feza Korkusuz
Objective Recent studies showed a potential of magnetic resonance imaging (MRI), which can be used as an additional tool for diagnosing cartilage degeneration in the early stage. We designed a cross-sectional study in order to evaluate knee joint cartilage adaptation to running, using 3.0-T MRI equipped with the 3-dimensional turbo spin echo (VISTA = Volume ISotropic Turbo spin echo Acquisition) software. By this thickness (mm) and signal intensity (mean pixel value) can be quantified, which could be closely related to the fluid content of the knee joint cartilage, before and after running...
April 1, 2018: Cartilage
https://www.readbyqxmd.com/read/29675625/multidetector-ct-of-iatrogenic-and-self-inflicted-vascular-lesions-and-infections-at-the-groin
#19
REVIEW
Massimo Tonolini, Anna Maria Ierardi, Gianpaolo Carrafiello, Domenico Laganà
The number and complexity of endovascular procedures performed via either arterial or venous access are steadily increasing. Albeit associated with higher morbidity compared to the radial approach, the traditional common femoral artery remains the preferred access site in a variety of cardiac, aortic, oncologic and peripheral vascular procedures. Both transarterial and venous cannulation (for electrophysiology, intravenous laser ablation and central catheterisation) at the groin may result in potentially severe vascular access site complications (VASC)...
April 19, 2018: Insights Into Imaging
https://www.readbyqxmd.com/read/29675570/driving-ability-after-right-sided-puncture-of-the-common-femoral-artery-during-coronary-angiography
#20
Christoph Brenner, Raoul Fuehring, David Niederseer, Rudolf Kirchmair, Christian Haid, Michael Liebensteiner
OBJECTIVES/BACKGROUND: To assess brake reaction time (BRT; key factor in driving ability) in patients receiving transfemoral coronary angiography (CAG). We assumed that patients would have a significantly impaired BRT after the procedure. METHODS: A prospective, observational study design was applied. Consecutive patients undergoing right-sided transfemoral CAG as part of the clinical routine were included. An experimental driving simulator was used to determine BRT after receiving a visual stimulus...
April 19, 2018: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
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