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https://www.readbyqxmd.com/read/29236180/diagnosis-medical-treatment-and-stepwise-mechanical-circulatory-support-for-fulminat-myocarditis
#1
Shunsuke Saito, Koichi Toda, Shigeru Miyagawa, Yasushi Yoshikawa, Hiroki Hata, Daisuke Yoshioka, Keitaro Domae, Yasumasa Tsukamoto, Yasushi Sakata, Yoshiki Sawa
Fulminant myocarditis is one of the most challenging diseases. We sought to examine the outcomes of our multidisciplinary treatment strategy for fulminant myocarditis. A retrospective review of consecutive 30 patients with fulminant myocarditis was conducted. Of the 30 patients, 25 required mechanical circulatory support (MCS). Percutaneous extracorporeal membrane oxygenation (ECMO) was the first-line therapy to rescue the patients and inserted in 23 of them. The other 2 were implanted with temporary ventricular assist device (t-VAD) with extracorporeal centrifugal pump(s)...
December 13, 2017: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/29236148/dual-antiplatelet-therapy-after-percutaneous-coronary-intervention-for-stable-cad-or-acs-redefining-the-optimal-duration-of%C3%A2-treatment
#2
B E Stähli, U Landmesser
The duration and combination of dual antiplatelet therapy after coronary stent implantation, consisting of aspirin and a P2Y12 inhibitor, is among the most intensely investigated therapeutic strategies in cardiovascular medicine. While initial studies have mainly focused on the efficacy and safety of individual antithrombotic agents, the increased need for a personalized, risk-based approach to define the optimal duration of antithrombotic treatment according to the estimated ischemic and bleeding risk was then recognized...
December 13, 2017: Herz
https://www.readbyqxmd.com/read/29236147/-platelet-inhibition-in-elderly-patients
#3
A Schäfer, J Bauersachs
Single antiplatelet therapy (SAPT) using predominantly acetylsalicylic acid (ASA) is the baseline anti-thrombotic therapy in primary as well as secondary prevention of atherosclerotic disease. Dual antiplatelet therapy (DAPT) is the cornerstone of maintenance medication following elective percutaneous coronary interventions or acute coronary syndromes (ST elevation myocardial infarction, non-ST elevation myocardial infarction and unstable angina pectoris). In the past the duration of DAPT in particular has been frequently discussed...
December 13, 2017: Herz
https://www.readbyqxmd.com/read/29234734/endovascular-aneurysm-sealing-for-management-of-aortic-occlusive-disease
#4
Ahmed Elbasty, Michael Crawford, Darren Morrow
Introduction: Endovascular management of aortic occlusive disease is an alternative to open surgery. This case describes the use of a Nellix graft to treat infrarenal aortic stenosis, outwith the graft indication for use. Case report: A 71 year old man with multiple comorbidities, presented with bilateral buttock claudication. A computed tomography angiogram (CTA) showed significant infrarenal aortic stenosis. Under local anaesthetic, using a percutaneous approach, Nellix grafts were inserted...
2017: EJVES Short Reports
https://www.readbyqxmd.com/read/29234639/hepatocellular-carcinoma-with-macrovascular-invasion-defining-the-optimal-treatment-strategy
#5
REVIEW
Charlotte E Costentin, Cristina R Ferrone, Ronald S Arellano, Suvranu Ganguli, Theodore S Hong, Andrew X Zhu
Background: Tumoral macrovascular invasion (MVI) of hepatic and/or portal vein branches is a common phenomenon in hepatocellular carcinoma (HCC) and is associated with poorer prognosis when compared to HCC without MVI. Summary: Current international guidelines for the management of HCC recommend sorafenib as the only treatment option in case of MVI. Despite guideline recommendations, several alternative options have been tested to manage HCC with MVI: surgery, transarterial chemoembolization, external or internal radiation, hepatic arterial infusion chemotherapy, percutaneous treatment, cryotherapy, or the combination of two or more of these strategies, with or without sorafenib...
November 2017: Liver Cancer
https://www.readbyqxmd.com/read/29234533/trends-of-intervention-for-paediatric-stone-disease-over-the-last-two-decades-2000-2015-a-systematic-review-of-literature
#6
REVIEW
Amelia Pietropaolo, Silvia Proietti, Patrick Jones, Karan Rangarajan, Omar Aboumarzouk, Guido Giusti, Bhaskar K Somani
Objective: To ascertain the publication trends of interventions for paediatric kidney stone disease (KSD) we conducted a systematic review of literature over the last 16 years. Patients and methods: With a rise of paediatric KSD and related interventions, a systematic review using PubMed was done over the last 16 years for all published papers on 'Paediatric stone disease intervention - ureteroscopy (URS), shockwave lithotripsy (SWL), percutaneous nephrolithotomy (PCNL), open stone surgery, and laparoscopic stone surgery'...
December 2017: Arab Journal of Urology
https://www.readbyqxmd.com/read/29234531/ultra-mini-percutaneous-nephrolithotomy-pcnl-versus-standard-pcnl-a-randomised-clinical-trial
#7
Ramin Haghighi, Hossein Zeraati, Maryam Ghorban Zade
Objective: To assess the effectiveness and advantages of ultra-mini-percutaneous nephrolithotomy (UM-PCNL) versus standard PCNL (S-PCNL), as one of the most important differences between the various PCNL techniques is the size of the renal access, which contributes to the broad spectrum of complications and outcomes. Patients and methods: This clinical randomised trial was conducted in 2016. In all, 70 patients with renal or upper ureteric stones of 10-20 mm in diameter, who were candidates for PCNL, were divided equally into two groups...
December 2017: Arab Journal of Urology
https://www.readbyqxmd.com/read/29233749/an-amendment-to-the-neidre-and-macnab-classification-system-for-lumbosacral-nerve-root-anomaly-and-its-implication-in-percutaneous-endoscopic-lumbar-discectomy
#8
Chen Yu, Chang Zhengqi, Yu Xiuchun
BACKGROUND: Lumbar disc herniation complicated with nerve root anomaly presents great challenges to diagnosis and treatment, improper selection of surgical procedures may cause inferior outcomes and neurological injury. CASE DESCRIPTION: A 66-year old male presented with low back pain and radicular symptoms involving bilateral L-5 and S-1 nerve roots. Instead of percutaneous endoscopic lumbar discectomy, aggressive decompression was carried out due to deviation between examination and imaging findings...
December 9, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29233212/percutaneous-closure-of-a-large-patent-ductus-arteriosus-in-a-preterm-newborn-weighing-1400-g-without-using-arterial-sheath-an-innovative-technique
#9
Gaurav Garg, Vishal Garg, Amit Prakash
Percutaneous closure of patent ductus arteriosus is well established in infants weighing >5 kg, but data regarding outcome of preterm especially very low birth weight infants is minimal. Although surgical ligation of patent ductus arteriosus is the preferred and well-accepted modality of treatment after failure of drug therapy in preterm infants, it has also got its own demerits in such a small and fragile subset. Device closure in infants weighing <1.5 kg is rarely attempted because of high chances of complications, especially acute arterial injury due to the arterial sheath...
December 13, 2017: Cardiology in the Young
https://www.readbyqxmd.com/read/29233162/sarcomatoid-hepatocellular-carcinoma-shc-a-case-report
#10
Yingying Yu, Yanping Zhong, Jingyu Wang, Di Wu
BACKGROUND: Sarcomatoid hepatocellular carcinoma (SHC) is a rare malignant hepatic tumor. Recurrent interventional therapies such as transcatheter arterial chemo-embolization (TACE), radiofrequency ablation (RFA), and percutaneous ethanol injection have been reported previously utilized in a majority of SHC cases. To date, the exact pathogenic mechanisms underlying sarcomatoid transformation of hepatocellular carcinoma (HCC) remain unknown. CASE PRESENTATION: In this study, we report a 68-year-old female SHC patient admitted to our hospital due to discrete abdominal distention for more than 20 days...
December 12, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29233155/a-meta-model-for-computer-executable-dynamic-clinical-safety-checklists
#11
Shan Nan, Pieter Van Gorp, Xudong Lu, Uzay Kaymak, Hendrikus Korsten, Richard Vdovjak, Huilong Duan
BACKGROUND: Safety checklist is a type of cognitive tool enforcing short term memory of medical workers with the purpose of reducing medical errors caused by overlook and ignorance. To facilitate the daily use of safety checklists, computerized systems embedded in the clinical workflow and adapted to patient-context are increasingly developed. However, the current hard-coded approach of implementing checklists in these systems increase the cognitive efforts of clinical experts and coding efforts for informaticists...
December 12, 2017: BMC Medical Informatics and Decision Making
https://www.readbyqxmd.com/read/29232970/primary-coronary-intervention-in-octogenarians-and-nonagenarians-with-st-segment-elevation-myocardial-infarction-a-canadian-single-center-perspective
#12
Rajat Sharma, Brett Hiebert, David Cheung, Davinder S Jassal, Kunal Minhas
The proportion of individuals >80 years of age constitute an increasing proportion of patients who present with ST-segment elevation myocardial infarction (STEMI). The objective of this study is to evaluate in-hospital outcomes and 1-year survival of very elderly patients who present with an STEMI and undergo primary percutaneous coronary intervention (pPCI). Between 2009 and 2015, individuals >80 years of age (very elderly patients) with an STEMI presenting at a single tertiary Canadian care center were included in the study...
January 1, 2017: Angiology
https://www.readbyqxmd.com/read/29232889/preparation-characterization-and-biological-activities-of-topical-anti-aging-ingredients-in-a-citrus-junos-callus-extract
#13
Deepak Adhikari, Vijay Kumar Panthi, Rudra Pangeni, Hyun Jung Kim, Jin Woo Park
In this study, we prepared and characterized a callus extract from Citrus junos and assessed its utility as a source of topical anti-aging ingredients. Callus extract was produced by aqueous extraction from Citrus junos grown on Murashige and Skoog medium with picloram as a growth regulator. After measuring the total phenolic and flavonoid contents, the major phenolic compound in calli was identified as p-hydroxycinnamoylmalic acid (1) by spectroscopic analysis. The total phenol content in the extract was determined to be 24...
December 11, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29232803/-successful-embolization-for-recurrent-varicocele-of-testis-after-microsurgical-subinguinal-varicocelectomy
#14
Mai Kimakura, Akira Nagahara, Shinichiro Fukuhara, Kazutoshi Fujita, Motohide Uemura, Hiroshi Kiuchi, Ryoichi Imamura, Yasushi Miyagawa, Hiroki Higashihara, Keigo Osuga, Norio Nonomura
Microscopic subinguinal varicocelectomy has a recurrence of less than 1%, and varicocele recurrence is supposed to be an uncommon post-surgery adverse event. At present, no guidelines exist for the management of recurrent varicoceles after surgery. In this report, we present two cases of post-surgery recurrent varicocele of the testis. Case_1 : A 23-year-old male patient who had undergone microscopic subinguinal varicocelectomy for a grade 3 varicocele was referred to our hospital because of recurrent varicocele...
November 2017: Hinyokika Kiyo. Acta Urologica Japonica
https://www.readbyqxmd.com/read/29232210/response-percutaneous-vascular-interventions-versus-bypass-surgeries-in-patients-with-critical-limb-ischemia
#15
Chi Shu, Jiarong Wang, Yazhou He, Jichun Zhao
No abstract text is available yet for this article.
December 11, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/29232184/feasibility-and-safety-of-intrathoracic-biopsy-and-repeat-biopsy-for-evaluation-of-programmed-cell-death-ligand-1-expression-for-immunotherapy-in-non-small-cell-lung-cancer
#16
Emily B Tsai, Kelsey Pomykala, Kathleen Ruchalski, Scott Genshaft, Fereidoun Abtin, Antonio Gutierrez, Hyun J Kim, Alice Li, Carlos Adame, Ashkan Jalalian, Brian Wolf, Edward B Garon, Jonathan W Goldman, Robert Suh
Purpose To determine feasibility and safety of biopsy and repeat biopsy for assessment of programmed cell death ligand-1 (PD-L1) status. Materials and Methods This retrospective analysis reviewed 101 patients who underwent transthoracic core needle biopsy for the KEYNOTE-001 (MK-3475) clinical trial of pembrolizumab, an antiprogrammed cell death-1 therapy for non-small cell lung cancer, from May 2012 to September 2014. Sixty-one male patients (mean age, 66.1 years; range 36-83 years) and 40 female patients (mean age, 66...
December 12, 2017: Radiology
https://www.readbyqxmd.com/read/29231917/stable-coronary-artery-disease-medical-treatment
#17
REVIEW
Rafał Dąbrowski, Marcin Dobrowolski
The crucial issues in optimal medical therapy to improve prognosis and reduce angina symptoms are secondary prevention, effective control of concomitant diseases, risk factors and medical treatment. In spite of successful percutaneous coronary interventions (PCI) and medical treatment with beta-blockers, ACE-inhibitors or angiotensin receptor blockers, statins and antiplatelet drugs, some patients are still symptomatic. In the era of PCI not sufficient attention is paid to other drugs reducing the incidence of angina episodes: calcium antagonists, long-acting nitrates, metabolic agents and novel antianginal drugs...
November 23, 2017: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29231858/anti-allergic-activity-of-monoacylated-ascorbic-acid-2-glucosides
#18
Kaori Miura, Yuta Morishita, Hiroaki Matsuno, Yusuke Aota, Hideyuki Ito, Akihiro Tai
2-O-α-d-Glucopyranosyl-l-ascorbic acid (AA-2G) is one of the stable ascorbic acid (AA) derivatives known as provitamin C agents. We have previously synthesized two types of monoacylated derivatives of AA-2G, 6-O-acyl-2-O-α-d-glucopyranosyl-l-ascorbic acids having a straight-acyl chain of varying length from C₄ to C18 (6-sAcyl-AA-2G) and a branched-acyl chain of varying length from C₆ to C16 (6-bAcyl-AA-2G) in order to improve the bioavailability of AA-2G. In this study, 6-sAcyl-AA-2G and 6-bAcyl-AA-2G per se showed the inhibitory effects on hyaluronidase activity and degranulation...
December 12, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29231757/structured-protocol-for-benign-biliary-anastomotic-strictures-impact-on-long-term-clinical-effectiveness
#19
Will S Lindquester, J David Prologo, Elizabeth A Krupinski, Gail L Peters
OBJECTIVE: The purpose of this study is to compare long-term clinical effectiveness before and after implementation of a structured protocol for percutaneous drainage of benign anastomotic biliary strictures. MATERIALS AND METHODS: Three hundred five adult patients undergoing percutaneous biliary drainage for biliary anastomotic strictures between 1994 and 2015 were identified using Current Procedural Terminology billing codes, with 234 undergoing intervention before implementation of a structured protocol and 71 undergoing intervention after implementation of the protocol...
December 12, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/29231067/in-vitro-artifact-assessment-of-an-mr-compatible-microwave-antenna-device-for-percutaneous-tumor-ablation-with-fluoroscopic-mri-sequences
#20
David-Emanuel Kessler, Jakob Weiss, Hansjörg Rempp, Philippe L Pereira, Konstantin Nikolaou, Stephan Clasen, Rüdiger Hoffmann
OBJECTIVE: To evaluate artifact configuration and diameters of a magnetic resonance (MR) compatible microwave (MW) applicator using near-realtime MR-fluoroscopic sequences for percutaneous tumor ablation procedures. MATERIAL AND METHODS: Two MW applicators (14 G and 16 G) were tested in an ex-vivo phantom at 1.5 T with two 3 D fluoroscopic sequences: T1-weighted spoiled Gradient Echo (GRE) and T1/T2-weighted Steady State Free Precession (SSFP) sequence. Applicator orientation to main magnetic field (B0), slice orientation and phase encoding direction (PED) were systematically varied...
December 12, 2017: Minimally Invasive Therapy & Allied Technologies: MITAT
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