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https://www.readbyqxmd.com/read/29161785/intraoperative-mri-for-resection-of-intracranial-meningiomas
#1
Shamik Chakraborty, Salvatore Zavarella, Sussan Salas, Michael Schulder
Objective: To examine whether intraoperative MRI can enhance safety and extent of resection of complex intracranial meningiomas, given its positive role in the resection of malignant brain tumors and pituitary tumors. Methods: Over a ten-year period, 70 operations were performed on 66 patients with intracranial meningiomas using the compact, mobile PoleStar N20 iMRI navigation system. A retrospective review was conducted examining patient demographics, surgical characteristics, and outcomes...
November 2017: Journal of Experimental Therapeutics & Oncology
https://www.readbyqxmd.com/read/29161637/la-donna-%C3%A3-mobile-lack-of-cyclical-shifts-in-facial-symmetry-and-facial-and-body-masculinity-preferences-a-hormone-based-study
#2
Urszula M Marcinkowska, Andrzej Galbarczyk, Grazyna Jasienska
Although under investigation for more than two decades, a common agreement on the occurrence of cyclical shifts in women's masculinity and symmetry preferences is still missing. Such shifts are considered to be an important feature of sexual selection as they supposedly direct women's attention towards cues for "good genes" (e.g. masculinity and symmetry) during times when probability of conception is the highest. Multiple studies have, however, failed to find these shifts. We attempt to address this lack of agreement analysing a sample of 110 healthy women, using intra-participant design and repeated measurements of oestradiol and LH during the cycle...
November 14, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/29161611/the-application-of-ion-mobility-mass-spectrometry-to-metabolomics
#3
REVIEW
Xing Zhang, Kevin Quinn, Charmion Cruickshank-Quinn, Richard Reisdorph, Nichole Reisdorph
Mass spectrometry-based metabolomics is being increasingly utilized in various research fields including investigating human diseases, nutrition, industrial applications, and plant/natural products studies. Although new analytical approaches have enhanced the performance of metabolomic analyses, significant challenges associated with throughput, metabolome coverage, and compound identification still exist. Ion mobility mass spectrometry offers great potential for improving throughput and depth of coverage in metabolomics experiments...
November 18, 2017: Current Opinion in Chemical Biology
https://www.readbyqxmd.com/read/29161592/tumor-suppressor-inactivation-of-gdf11-occurs-by-precursor-sequestration-in-triple-negative-breast-cancer
#4
Sameer S Bajikar, Chun-Chao Wang, Michael A Borten, Elizabeth J Pereira, Kristen A Atkins, Kevin A Janes
Triple-negative breast cancer (TNBC) is an aggressive and heterogeneous carcinoma in which various tumor-suppressor genes are lost by mutation, deletion, or silencing. Here we report a tumor-suppressive mode of action for growth-differentiation factor 11 (GDF11) and an unusual mechanism of its inactivation in TNBC. GDF11 promotes an epithelial, anti-invasive phenotype in 3D triple-negative cultures and intraductal xenografts by sustaining expression of E-cadherin and inhibitor of differentiation 2 (ID2). Surprisingly, clinical TNBCs retain the GDF11 locus and expression of the protein itself...
November 20, 2017: Developmental Cell
https://www.readbyqxmd.com/read/29161511/a-customizable-flow-injection-system-for-automated-high-throughput-and-time-sensitive-ion-mobility-spectrometry-and-mass-spectrometry-measurements
#5
Daniel J Orton, Malak M Tfaily, Ronald J Moore, Brian L LaMarche, Xueyun Zheng, Thomas L Fillmore, Rosalie K Chu, Karl K Weitz, Matthew E Monroe, Ryan T Kelly, Richard D Smith, Erin Shammel Baker
To better understand disease conditions and environmental perturbations, multi-omic studies combining proteomic, lipidomic, and metabolomic analyses are vastly increasing in popularity. In a multi-omic study, a single sample is typically extracted in multiple ways and various analyses are performed using different instruments. Thus, one sample becomes many measurements, making high throughput and reproducible evaluations a necessity. One way to address the numerous samples and varying instrumental conditions is to utilize a flow injection analysis (FIA) system for rapid sample injection...
November 21, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/29161270/tracking-urban-human-activity-from-mobile-phone-calling-patterns
#6
Daniel Monsivais, Asim Ghosh, Kunal Bhattacharya, Robin I M Dunbar, Kimmo Kaski
Timings of human activities are marked by circadian clocks which in turn are entrained to different environmental signals. In an urban environment the presence of artificial lighting and various social cues tend to disrupt the natural entrainment with the sunlight. However, it is not completely understood to what extent this is the case. Here we exploit the large-scale data analysis techniques to study the mobile phone calling activity of people in large cities to infer the dynamics of urban daily rhythms. From the calling patterns of about 1,000,000 users spread over different cities but lying inside the same time-zone, we show that the onset and termination of the calling activity synchronizes with the east-west progression of the sun...
November 2017: PLoS Computational Biology
https://www.readbyqxmd.com/read/29161046/heavy-metal-free-tannin-from-bark-for-sustainable-energy-storage
#7
Alolika Mukhopadhyay, Yucong Jiao, Rui Katahira, Peter N Ciesielski, Michael E Himmel, Hongli Zhu
A novel renewable cathode made from earth-abundant, low-cost materials can contribute to the intermittent storage needs of renewable energy based society. Inspired by Nature, we report for the first-time tannin as a cathode material. Our approach exploits the charge storage mechanism of the redox active quinone moiety. Tannins extracted from tree bark using environmental friendly aqueous solvents has the highest phenol content (5.56 mol g-1) among all the natural phenolic biopolymers, 5000 times higher than lignin...
November 21, 2017: Nano Letters
https://www.readbyqxmd.com/read/29161024/performance-and-stability-enhancement-of-in-sn-zn-o-tfts-using-sio2-gate-dielectrics-grown-by-low-temperature-atomic-layer-deposition
#8
Jiazhen Sheng, Ju-Hwan Han, Wan-Ho Choi, Jozeph Park, Jin-Seong Park
Silicon dioxide (SiO2) films were synthesized by plasma enhanced atomic layer deposition (PEALD) using BTBAS (bis(tertiarybutylamino) silane) as the precursor and O2 plasma as the reactant, at a temperature range of 50 to 200 °C. While dielectric constant values larger than 3.7 are obtained at all deposition temperatures, the leakage current levels are drastically reduced to below 10-12 A at temperatures above 150 °C, which are similar to those obtained in thermally oxidized and PECVD grown SiO2. Thin film transistors (TFTs) based on In-Sn-Zn-O (ITZO) semiconductors were fabricated using thermal SiO2, PECVD SiO2 and PEALD SiO2 grown at 150 °C as the gate dielectrics, and superior device performance and stability are observed in the last case...
November 21, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29160826/the-communication-awareness-relationships-and-empowerment-c-a-r-e-model-an-effective-tool-for-engaging-urban-communities-in-community-based-participatory-research
#9
Joniqua Ceasar, Marlene H Peters-Lawrence, Valerie Mitchell, Tiffany M Powell-Wiley
Little is known about recruitment methods for racial/ethnic minority populations from resource-limited areas for community-based health and needs assessments, particularly assessments that incorporate mobile health (mHealth) technology for characterizing physical activity and dietary intake. We examined whether the Communication, Awareness, Relationships and Empowerment (C.A.R.E.) model could reduce challenges recruiting and retaining participants from faith-based organizations in predominantly African American Washington, D...
November 21, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29160797/target-tracking-with-sensor-navigation-using-coupled-rss-and-aoa-measurements
#10
Slavisa Tomic, Marko Beko, Rui Dinis, João Pedro Gomes
This work addresses the problem of tracking a signal-emitting mobile target in wireless sensor networks (WSNs) with navigated mobile sensors. The sensors are properly equipped to acquire received signal strength (RSS) and angle of arrival (AoA) measurements from the received signal, while the target transmit power is assumed not known. We start by showing how to linearize the highly non-linear measurement model. Then, by employing a Bayesian approach, we combine the linearized observation model with prior knowledge extracted from the state transition model...
November 21, 2017: Sensors
https://www.readbyqxmd.com/read/29160694/quick-and-selective-dual-mode-detection-of-h2s-gas-by-mobile-app-employing-silver-nanorods-array
#11
Shashank Kumar Gahlaut, Kavita Yadav, Chandrashekhar Sharan, Jitendra Pratap Singh
Hydrogen sulfide (H2S) is a hazardous gas, which not only harms living beings but also poses a significant risk to damage materials placed in culture and art museums, due to its corrosive nature. We demonstrate a novel approach for selective rapid detection of H2S gas using silver nanorods (AgNRs) array on glass substrate at ambient conditions. The arrays were prepared by glancing angle deposition method. The colorimetric and water wetting properties of as-fabricated arrays were found to be highly sensitive towards the sulfurization, in the presence of H2S gas with a minimal concentration in ppm range...
November 21, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/29160686/human-hair-keratin-for-biocompatible-flexible-and-transient-electronic-devices
#12
Jieun Ko, Luong Thi Hieun Nguyen, Abhijith Surendran, Bee Yi Tan, Kee Woei Ng, Wei Lin Leong
Biomaterials have been attracting attention as a useful building block for biocompatible and bioresorbable electronics due to its non-toxic property and solution processabillity. In this work, we report the integration of biocompatible keratin from human hair as dielectric layer for organic thin-film transistors (TFTs), with high performance, flexibility and transient property. The keratin dielectric layer exhibited a high capacitance value above 1.27 μF/cm2 at 20 Hz due to the formation of electrical double layer...
November 21, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29160442/effects-of-socioeconomic-position-and-social-mobility-on-linear-growth-from-early-childhood-until-adolescence
#13
Ana Paula Muraro, Rita Adriana Gomes de Souza, Paulo Rogério Melo Rodrigues, Márcia Gonçalves Ferreira, Rosely Sichieri
OBJECTIVE: To assess the effect of socioeconomic position (SEP) in childhood and social mobility on linear growth through adolescence in a population-based cohort. METHODS: Children born in Cuiabá-MT, central-western Brazil, were evaluated during 1994 - 1999. They were first assessed during 1999 - 2000 (0 - 5 years) and again during 2009 - 2011 (10 - 17 years), and their height-for-age was evaluated during these two periods.Awealth index was used to classify the SEP of each child's family as low, medium, or high...
July 2017: Revista Brasileira de Epidemiologia, Brazilian Journal of Epidemiology
https://www.readbyqxmd.com/read/29160366/erdosteine-ameliorates-the-harmful-effects-of-ischemia-reperfusion-injury-on-the-liver-of-rats
#14
Aziz Mutlu Barlas, Kemal Kismet, Serap Erel, Serdar Kuru, Turgut Cavusoglu, Mehmet Senes, Zeynep Adiyaman, Pinar Celepli, Sema Hucumenoglu, Recep Pekcici
PURPOSE: To investigate the potential protective effects of erdosteine against the harmful effects of ischemia-reperfusion injury on the liver in an experimental rat model. METHODS: Forty rats were divided into 4 groups. In the sham group, only the hepatic pedicle was mobilized. No other manipulation or treatment was performed. In the other groups, ischemia was achieved by clamping the hepatic pedicle for 60 min. After that, 90 min reperfusion was provided. In the control group, no treatment was given...
October 2017: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/29160068/regioregular-bis-pyridal-2-1-3-thiadiazole-based-semiconducting-polymer-for-high-performance-ambipolar-transistors
#15
Chunguang Zhu, Zhiyuan Zhao, Huajie Chen, Liping Zheng, Xiaolin Li, Jinyang Chen, Yanming Sun, Feng Liu, Yunlong Guo, Yunqi Liu
We report a regioregular bis-pyridal[2,1,3]-thiadiazole (BPT) acceptor strategy to construct the first ambipolar pyridal[2,1,3]thiadiazole-based semiconducting polymer (PBPTV). The use of BPT unit enables PBPTV to achieve high electron affinity, low LUMO level, and extended π-conjugation. All these factors provide PBPTV with encouraging hole and electron mobilities up to 6.87 and 8.49 cm2 V-1 s-1, respectively. Our work demonstrates that the BPT unit is a promising building block for designing high-performance electron-transporting semiconductors in organic electronics...
November 21, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/29160062/arsenene-based-heterostructures-high-efficient-bifunctional-materials-for-photovoltaics-and-photocatalytics
#16
Xianghong Niu, Yunhai Li, QiongHua Zhou, Huabing Shu, Jinlan Wang
Constructing suitable type II heterostructures is a reliable solution for high-efficient photovoltaic and photocatalytic materials. Arsenene, as a rising member of mono-elemental two-dimensional materials, shows great potential as a building block of heterostructures due to its suitable band gap, high carrier mobility and good optical properties. Based on accurate band structure calculations by combining many-body perturbation GW method with an extrapolation technique, we demonstrate that arsenene-based heterostructures paired with molybdenum disulfide, tetracyano-quinodimethane or tetracyanonaphtho-quinodimethane can form type-II band alignments...
November 21, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29160003/two-new-viruses-mcv1-and-mcv2-which-infect-marinitoga-bacteria-isolated-from-deep-sea-hydrothermal-vents-functional-and-genomic-analysis
#17
C Mercier, J Lossouarn, C L Nesbø, T H A Haverkamp, A C Baudoux, M Jebbar, N Bienvenu, S Thiroux, S Dupont, C Geslin
Viruses represent a driving force in the evolution of microorganisms including those thriving in extreme environments. However, our knowledge of the viral diversity associated to microorganisms inhabiting the deep-sea hydrothermal vents remains limited. The phylum of Thermotogae, including thermophilic bacteria, is well represented in this environment. Only one virus was described in this phylum, MPV1 carried by Marinitoga piezophila. In this study, we report on the functional and genomic characterization of two new bacterioviruses that infect bacteria from the Marinitoga genus...
November 21, 2017: Environmental Microbiology
https://www.readbyqxmd.com/read/29159972/vitamin-b12-deficiency-and-impaired-expression-of-amnionless-during-aging
#18
Alice Pannérec, Eugenia Migliavacca, Antonio De Castro, Joris Michaud, Sonia Karaz, Laurence Goulet, Serge Rezzi, Tze Pin Ng, Nabil Bosco, Anis Larbi, Jerome N Feige
BACKGROUND: Physical frailty and loss of mobility in elderly individuals lead to reduced independence, quality of life, and increased mortality. Vitamin B12 deficiency has been linked to several age-related chronic diseases, including in the musculo-skeletal system, where vitamin B12 deficiency is generally believed to be linked to poor nutritional intake. In the present study, we asked whether aging and frailty associate with altered vitamin B12 homeostasis in humans and investigated the underlying molecular mechanisms using preclinical models...
November 21, 2017: Journal of Cachexia, Sarcopenia and Muscle
https://www.readbyqxmd.com/read/29159919/smart-phone-accessibility-and-mhealth-use-in-a-limited-resource-setting
#19
Shelby L Garner, Tanya Sudia, Spurgeon Rachaprolu
AIM: To determine smartphone access and use including future opportunities for mHealth and potential ethical implications among health care professionals practicing at a health care facility in Bengaluru, India. BACKGROUND: The evolution of smart phones can provide convenient, portable, and rapid access to resources for health care professionals. While mobile phone accessibility has improved in recent years in many low and middle-income countries, the use of smart phones to address health priorities remains limited in some limited resource settings...
November 20, 2017: International Journal of Nursing Practice
https://www.readbyqxmd.com/read/29159782/cecal-bascule-a-systematic-review-of-the-literature
#20
REVIEW
B E Lung, S B Yelika, A S Murthy, M Gachabayov, P Denoya
BACKGROUND: Cecal volvulus is a rare clinical entity with an average incidence of 2.8-7.1 per million people per year, accounting for 1-2% of all large bowel obstructions. Cecal bascule is the rarest type of cecal volvulus, accounting for 5-20% of all cases. Although several case reports have been published, there is no consensus regarding its diagnosis and treatment. The aim of this study was to review the literature on cecal bascule in order to summarize the etiopathogenesis, clinical features, diagnosis, and treatment options...
November 20, 2017: Techniques in Coloproctology
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