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https://www.readbyqxmd.com/read/29055286/in-defense-of-progesterone-a-review-of-the-literature
#1
Allan Lieberman, Luke Curtis
Context • The medical literature on the use of progesterone in postmenopausal women is often confusing and contradictory. Some physicians implicate natural progesterone in an increase in the risk of breast cancer. The chemical structure of natural progesterone (P4) is quite different from chemically altered, synthetic chemicals called progestins, which results in different actions at the cell level. Objective • The research team intended to review the literature to examine the benefits and safety of natural progesterone and determine whether it can cause an increase or decrease in breast cancer risk...
October 21, 2017: Alternative Therapies in Health and Medicine
https://www.readbyqxmd.com/read/29052948/association-of-participant-preferences-on-work-and-school-participation-after-a-first-episode-of-psychosis
#2
Alexandra de Waal, Lisa B Dixon, Jennifer L Humensky
AIM: To explore baseline ratings of importance (ROI) across life domains for participants in the Recovery After an Initial Schizophrenia Episode Connection Program (RAISE CP), and investigate whether ratings were correlated with intervention outcomes over time. METHODS: At baseline, 63 participants rated the importance of reducing symptoms, side-effects, confusion, increasing energy and school/work functioning and improving social relations. ROIs were examined in relation to work/school participation (n = 41) and occupational functioning (n = 37) after 12 months...
October 20, 2017: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/29052771/standardized-radiographic-interpretation-of-thoracic-tuberculosis-in-children
#3
REVIEW
Nathan David P Concepcion, Bernard F Laya, Savvas Andronikou, Pedro A N Daltro, Marion O Sanchez, Jacqueline Austine U Uy, Timothy Reynold U Lim
There is a lack of standardized approach and terminology to classify the diverse spectrum of manifestations in tuberculosis. It is important to recognize the different clinical and radiographic patterns to guide treatment. As a result of changing epidemiology, there is considerable overlap in the radiologic presentations of primary tuberculosis and post-primary tuberculosis. In this article we promote a standardized approach in clinical and radiographic classification for children suspected of having or diagnosed with childhood tuberculosis...
September 2017: Pediatric Radiology
https://www.readbyqxmd.com/read/29052405/-its2-sequence-analysis-and-identification-of-medicinal-artemisia-plants
#4
Yao-Yao Ren, Nan-Ping Jiang, Rui-Ying Liu, Liang-Ke Song, Rui Tan, Jian Gu
Artemisia hedinii occupies an important position in the Tibetan medicine. Plants in Artemisia vary a lot and are widely distributed in the Qinghai-Tibet Plateau, many plants in Artemisia look similar, making traditional identification methods laborious. In this article, ITS2 sequences were used as DNA barcoding to identify four kinds of confusable Tibetan medicine plants in Artemisia, aiming to establish a rapid and accurate identification methods. Twenty-one samples in Artemisia were collected from the Qinghai-Tibet Plateau, ITS2 sequence PCR amplification and sequencing were conducted after the extraction of DNA...
April 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29050907/difficulties-in-using-personal-protective-equipment-training-experiences-with-the-2015-outbreak-of-middle-east-respiratory-syndrome-in-korea
#5
JaHyun Kang, Eun Jin Kim, Jeong Hwa Choi, Hae Kyung Hong, Si-Hyeon Han, In Soon Choi, Jae Geum Ryu, Jinwha Kim, Jae Yeun Kim, Eun Suk Park
This study aimed to evaluate practical barriers to personal protective equipment (PPE) use found through health care personnel (HCP) training sessions held during and after the 2015 Middle East respiratory syndrome outbreak in Korea. Difficulties observed were ill-fitting sizes, anxiety, confusion from unstandardized protocols, doubts about PPE quality and effectiveness, and complexity of using several PPE items together. Further research to generate robust evidence and repeated HCP trainings are necessary to ensure HCP and patient safety in future outbreaks...
October 16, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/29050898/sushi-cervice-and-gnathostomiasis-a-case-report-and-review-of-imported-infections
#6
REVIEW
Jordan Leroy, Marjorie Cornu, Anne Sophie Deleplancque, Séverine Loridant, Emmanuel Dutoit, Boualem Sendid
We describe a case of imported cutaneous gnathostomiasis in a Thai patient living in France. Gnathostomiasis is a zoonosis of food origin. The disease is endemic in Southeast Asia and Latin America. However, over the past 30 years, an increasing number of imported cases has been described in Europe and America. The disease is rare in Western Europe and the majority of cases described had a cutaneous clinical presentation. The disease may sometimes be confused with allergy, leading to a delay in diagnosis. Visceral symptoms are rare but may follow severe attacks...
October 16, 2017: Travel Medicine and Infectious Disease
https://www.readbyqxmd.com/read/29049268/patient-and-parent-satisfaction-with-sling-use-after-pediatric-upper-extremity-fractures-a-randomized-controlled-trial-of-a-customized-cast-sling-versus-standard-cast-and-sling
#7
Aristides I Cruz, Steven F DeFroda, Joseph A Gil, Heather Hansen, Alexandre Bolous, Michaela Procaccini, Mark R Zonfrillo
BACKGROUND: Long arm cast immobilization after operative and nonoperative treatment of pediatric upper extremity fractures is common. The use of a sling to aid in carrying the casted extremity as well as provide further immobilization is also common practice. Off-the-shelf slings vary in quality and fit, can be confusing for parents/patients to apply, and lead to frustration and dissatisfaction with its use. The purpose of this investigation was to compare patient/parent centered outcomes after the use of a customized sling compared with a standard sling by utilizing a prospective, randomized-controlled trial...
October 18, 2017: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/29048976/healthy-out-group-members-are-represented-psychologically-as-infected-in-group-members
#8
Michael Bang Petersen
A range of studies have demonstrated that people implicitly treat out-groups as the carriers of pathogens and that considerable prejudice against out-groups is driven by concerns about pathogens. Yet the psychological categories that are involved and the selection pressures that underlie these categories remain unclear. A common view is that human pathogen-avoidance psychology is specifically adapted to avoid out-groups because of their potentially different pathogens. However, the series of studies reported here shows that there is no dedicated category for reasoning about out-groups in terms of pathogens...
October 1, 2017: Psychological Science
https://www.readbyqxmd.com/read/29048307/assessing-aging-stereotypes-personal-stereotypes-self-stereotypes-and-self-perception-of-aging
#9
Rocío Fernández-Ballesteros, Ricardo Olmos, Marta Santacreu, Antonio Bustillos, Rocío Schettini, Carmen Huici, José M Rivera
BACKGROUND: There is a broad semantic network of aging stereotypes; where different concepts and their measurement are confused: personal stereotypes, self-stereotypes and self-perception of aging. METHOD: First, we analyze the translated version of the Image of Aging Scale (IAS) measurement model through exploratory and confirmatory factor analysis, with two representative sub-samples of the Spanish population aged over eighteen (N = 1,105) and in a sample of gerontologists and geriatricians (N = 325)...
November 2017: Psicothema
https://www.readbyqxmd.com/read/29047353/precision-medicine-for-all-challenges-and-opportunities-for-a-precision-medicine-approach-to-critical-illness
#10
REVIEW
Christopher W Seymour, Hernando Gomez, Chung-Chou H Chang, Gilles Clermont, John A Kellum, Jason Kennedy, Sachin Yende, Derek C Angus
All of medicine aspires to be precise, where a greater understanding of individual data will lead to personalized treatment and improved outcomes. Prompted by specific examples in oncology, the field of critical care may be tempted to envision that complex, acute syndromes could bend to a similar reductionist philosophy-where single mutations could identify and target our critically ill patients for treatment. However, precision medicine faces many challenges in critical care. These include confusion about terminology, uncertainty about how to divide patients into discrete groups, the challenges of multi-morbidity, scale, and the need for timely interventions...
October 18, 2017: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/29047072/involving-members-of-the-public-in-health-economics-research-insights-from-selecting-health-states-for-valuation-to-estimate-quality-adjusted-life-year-qaly-weights
#11
Elizabeth Goodwin, Kate Boddy, Lynn Tatnell, Annie Hawton
Over recent years, public involvement in health research has expanded considerably. However, public involvement in designing and conducting health economics research is seldom reported. Here we describe the development, delivery and assessment of an approach for involving people in a clearly defined piece of health economics research: selecting health states for valuation in estimating quality-adjusted life-years (QALYs). This involvement formed part of a study to develop a condition-specific preference-based measure of health-related quality of life, the Multiple Sclerosis Impact Scale (MSIS-8D), and the work reported here relates to the identification of plausible, or realistic, health states for valuation...
October 19, 2017: Applied Health Economics and Health Policy
https://www.readbyqxmd.com/read/29046725/clinical-photographic-observation-of-plantar-corns-and-callus-associated-with-a-nominal-scale-classification-and-inter-observer-reliability-study-in-a-student-population
#12
David R Tollafield
BACKGROUND: The management of plantar corns and callus has a low cost-benefit with reduced prioritisation in healthcare. The distinction between types of keratin lesions that forms corns and callus has attracted limited interest. Observation is imperative to improving diagnostic predictions and a number of studies point to some confusion as to how best to achieve this. The use of photographic observation has been proposed to improve our understanding of intractable keratin lesions. METHODS: Students from a podiatry school reviewed photographs where plantar keratin lesions were divided into four nominal groups; light callus (Grade 1), heavy defined callus (Grade 2), concentric keratin plugs (Grade 3) and callus with deeper density changes under the forefoot (Grade 4)...
2017: Journal of Foot and Ankle Research
https://www.readbyqxmd.com/read/29044842/changing-perspectives-on-the-strategic-use-of-microwave-heating-in-organic-synthesis
#13
REVIEW
Gregory B Dudley, A E Stiegman
This Personal Account describes collaborative investigations into apocryphal microwave effects in organic chemistry. Focused research on microwave-assisted organic synthesis has been fraught with confusion, controversy, and misinformation. Microwave heating is an undoubtedly useful tactic for organic synthesis, but whether or not it can offer strategic advantages remains an open question in the minds of many people. (Ironically, those who do not consider it an open question are split as to whether it has been resolved affirmatively or negatively...
October 18, 2017: Chemical Record: An Official Publication of the Chemical Society of Japan ... [et Al.]
https://www.readbyqxmd.com/read/29044304/delirium-in-a-latin-american-intensive-care-unit-a-prospective-cohort-study-of-mechanically-ventilated-patients
#14
Patricia Mesa, Ignacio José Previgliano, Sonia Altez, Silvina Favretto, María Orellano, Cinthya Lecor, Ana Soca, Ely Wesley
OBJECTIVE: To establish the prevalence of delirium in a general intensive care unit and to identify associated factors, clinical expression and the influence on outcomes. METHODS: This was a prospective cohort study in a medical surgical intensive care unit. The Richmond Agitation-Sedation Scale and Confusion Assessment Method for the Intensive Care Unit were used daily to identify delirium in mechanically ventilated patients. RESULTS: In this series, delirium prevalence was 80% (N = 184 delirious patients out of 230 patients)...
July 2017: Revista Brasileira de Terapia Intensiva
https://www.readbyqxmd.com/read/29044066/color-vision-abnormalities-in-type-ii-diabetes-sankara-nethralaya-diabetic-retinopathy-epidemiology-and-molecular-genetics-study-ii-report-no-2
#15
Laxmi Gella, Rajiv Raman, Vaitheeswaran Kulothungan, Swakshyar Saumya Pal, Suganeswari Ganesan, Sangeetha Srinivasan, Tarun Sharma
PURPOSE: The purpose of this study is to assess color vision abnormalities in a cohort of subjects with type II diabetes and elucidate associated risk factors. METHODS: Subjects were recruited from follow-up cohort of Sankara Nethralaya Diabetic Retinopathy Epidemiology and Molecular Genetics Study I. Six hundred and seventy-three eyes of 343 subjects were included from this population-based study. All subjects underwent detailed ophthalmic evaluation, including the Farnsworth-Munsell 100 hue test...
October 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29043692/-appendicitis-versus-nonspecific-acute-abdominal-pain-diagnostic-accuracy-of-ultrasound
#16
M Prada Arias, J L Vázquez, A Salgado Barreira, J Gómez Veiras, S García Saavedra, P Fernández Eire, M Montero Sánchez, J R Fernández Lorenzo
PURPOUSE: The aim of this study is to assess the diagnostic accuracy of ultrasound to differentiate appendicitis from nonspecific acute abdominal pain, that is the most common process requiring differential diagnosis in clinical practice. MATERIAL AND METHODS: Patients admitted for suspicion of appendicitis were prospectively evaluated in our hospital during two years (2013-2014). Cases of nonspecific acute abdominal pain and appendicitis assessed by ultrasound were enrolled in the study...
July 20, 2017: Cirugía Pediátrica: Organo Oficial de la Sociedad Española de Cirugía Pediátrica
https://www.readbyqxmd.com/read/29043671/dancing-with-the-stars-using-image-analysis-to-study-the-choreography-of-the-endoplasmic-reticulum-and-its-partners-and-of-movement-within-its-tubules
#17
Lawrence R Griffing
In this chapter, approaches to the image analysis of the choreography of the plant endoplasmic reticulum (ER) labeled with fluorescent fusion proteins ("stars," if you wish) are presented. The approaches include the analyses of those parts of the ER that are attached through membrane contact sites to moving or nonmoving partners (other "stars"). Image analysis is also used to understand the nature of the tubular polygonal network, the hallmark of this organelle, and how the polygons change over time due to tubule sliding or motion...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29043491/the-multifactorial-origin-of-posterior-reversible-encephalopathy-syndrome-in-cyclophosphamide-treated-lupus-patients
#18
REVIEW
Tatjana Zekić, Mirjana Stanić Benić, Ronald Antulov, Igor Antončić, Srđan Novak
The cyclophosphamide as a predisposing factor for Posterior Reversible Encephalopathy Syndrome (PRES) and therapeutic option for systemic lupus erythematosus (SLE) is still confusing. The first and only case of PRES, probably induced by cyclophosphamide, in Croatia followed by the findings of 36 SLE patients diagnosed with PRES after treatment with cyclophosphamide worldwide are described. An 18-year-old Caucasian female patient with a 1-year history of SLE was admitted to the hospital due to lupus nephritis and acute arthritis...
October 17, 2017: Rheumatology International
https://www.readbyqxmd.com/read/29040923/six-factors-of-adult-dyslexia-assessed-by-cognitive-tests-and-self-report-questions-very-high-predictive-validity
#19
Peter Tamboer, Harrie C M Vorst, Peter F de Jong
The Multiple Diagnostic Digital Dyslexia Test for Adults (MDDDT-A) consists of 12 newly developed tests and self-report questions in the Dutch language. Predictive validity and construct validity were investigated and compared with validity of a standard test battery of dyslexia (STB) in a sample of 154 students. There are three main results. First, various analyses of principal components showed that six or more factors of dyslexia can be distinguished (rapid naming, spelling, reading, short-term memory, confusion, phonology, attention, complexity)...
October 14, 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/29040566/overlapping-network-meta-analyses-on-the-same-topic-survey-of-published-studies
#20
F Naudet, E Schuit, J P A Ioannidis
Background: To assess how common it is for a published network meta-analysis (NMA) to have other published overlapping NMAs, and to evaluate these overlaps. Methods: A total of 88 NMAs of randomized controlled trials evaluating the comparative effectiveness of health interventions were randomly selected. For each of these, we searched for NMAs on the same topic. A random sample of 40 pairs (an index NMA and one of its overlapping NMAs) was selected to assess the overlap in terms of nodes, treatments and references...
August 3, 2017: International Journal of Epidemiology
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