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https://www.readbyqxmd.com/read/28634646/the-role-of-robotics-in-the-invasive-management-of-bladder-cancer
#1
REVIEW
Pramit Khetrapal, Wei Shen Tan, Benjamin Lamb, Melanie Tan, Hilary Baker, James Thompson, Ashwin Sridhar, John D Kelly, Tim Briggs
Robot-assisted radical cystectomy (RARC) has been adopted widely in many centres, owed largely to the success of robot-assisted laparoscopic prostatectomy (RALP). It aims to replicate the oncological outcomes of open radical cystectomy (ORC), while providing a shorter recovery period. Despite this, previous RCTs have failed to show a benefit for RARC over ORC. These trials have compared extracorporeal RARC (eRARC) with ORC, which requires a further incision to mobilise the bowel for urinary reconstruction with an open technique...
August 2017: Current Urology Reports
https://www.readbyqxmd.com/read/28634067/magnetic-graphene-coated-inorganic-organic-hybrid-nanocomposite-for-enhanced-preconcentration-of-selected-pesticides-in-tomato-and-grape
#2
Hamid Rashidi Nodeh, Hassan Sereshti, Hamid Gaikani, Muhammad Afzal Kamboh, Zahra Afsharsaveh
The new magnetic graphene based hybrid silica-N-[3-(trimethoxysilyl)propyl]ethylenediamine (MG@SiO2-TMSPED) nanocomposite was synthesized via sol-gel process, and used as an effective adsorbent in magnetic solid phase extraction (MSPE) of three selected pesticides followed by gas chromatography micro-electron capture detection (GC-μECD). The adsorbent was characterized using Fourier transform-infrared spectroscopy (FT-IR), Brunauer-Emmett-Teller (BET), Barrett-Joyner-Halenda (BJH), scanning electron microscopy (SEM), transmission electron microscopy (TEM), and energy dispersive X-ray spectroscopy (EDXS) techniques...
June 13, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28633996/effects-of-monoaminergic-drugs-on-training-induced-motor-cortex-plasticity-in-older-adults
#3
Trisha M Kesar, Samir R Belagaje, Paola Pergami, Marc W Haut, Gerald Hobbs, Cathrin M Buetefisch
Primary motor cortex (M1) plasticity is involved in motor learning and stroke motor recovery, and enhanced by increasing monoaminergic transmission. Age impacts these processes but there is a paucity of systematic studies on the effects of monoaminergic drugs in older adults. Here, in ten older adults (age 61+ 4 years, 4 males), we determine the effects of a single oral dose of carbidopa/levodopa (DOPA), d-amphetamine (AMPH), methylphenidate (MEPH) and placebo (PLAC) on M1 excitability and motor training-induced M1 plasticity...
June 17, 2017: Brain Research
https://www.readbyqxmd.com/read/28633857/state-of-the-art-on-ultrasonic-oil-production-technique-for-eor-in-china
#4
Zhenjun Wang, Congbo Yin
Ultrasonic oil production technique for enhanced oil recovery (EOR) attracts more attention due to its high adaptability, simple operation, low cost and zero pollution to the oil reservoir. In this paper, recent new downhole tools used for enhanced oil recovery developed in China are summarized. Furthermore, research advance on some key problems that affect the widespread application of ultrasonic oil production technique in China are also summarized in view of what are the primary factors that influence crude oil paraffin inhibition and viscosity reduction, whether ultrasonic excitation is better than chemical agent for any plugs removal and whether ultrasound-chemical combination plug removal technology has the best plugs removal effect...
September 2017: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/28633848/novel-synthesis-of-nanocomposite-for-the-extraction-of-sildenafil-citrate-viagra-from-water-and-urine-samples-process-screening-and-optimization
#5
Arash Asfaram, Mehrorang Ghaedi, Mihir Kumar Purkait
A sensitive analytical method is investigated to concentrate and determine trace level of Sildenafil Citrate (SLC) present in water and urine samples. The method is based on a sample treatment using dispersive solid-phase micro-extraction (DSPME) with laboratory-made Mn@ CuS/ZnS nanocomposite loaded on activated carbon (Mn@ CuS/ZnS-NCs-AC) as a sorbent for the target analyte. The efficiency was enhanced by ultrasound-assisted (UA) with dispersive nanocomposite solid-phase micro-extraction (UA-DNSPME). Four significant variables affecting SLC recovery like; pH, eluent volume, sonication time and adsorbent mass were selected by the Plackett-Burman design (PBD) experiments...
September 2017: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/28633681/copewell-a-conceptual-framework-and-system-dynamics-model-for-predicting-community-functioning-and-resilience-after-disasters
#6
Jonathan M Links, Brian S Schwartz, Sen Lin, Norma Kanarek, Judith Mitrani-Reiser, Tara Kirk Sell, Crystal R Watson, Doug Ward, Cathy Slemp, Robert Burhans, Kimberly Gill, Tak Igusa, Xilei Zhao, Benigno Aguirre, Joseph Trainor, Joanne Nigg, Thomas Inglesby, Eric Carbone, James M Kendra
OBJECTIVE: Policy-makers and practitioners have a need to assess community resilience in disasters. Prior efforts conflated resilience with community functioning, combined resistance and recovery (the components of resilience), and relied on a static model for what is inherently a dynamic process. We sought to develop linked conceptual and computational models of community functioning and resilience after a disaster. METHODS: We developed a system dynamics computational model that predicts community functioning after a disaster...
June 21, 2017: Disaster Medicine and Public Health Preparedness
https://www.readbyqxmd.com/read/28633091/cyclic-alternating-pattern-and-interictal-epileptiform-discharges-during-morning-sleep-after-sleep-deprivation-in-temporal-lobe-epilepsy
#7
Filippo Sean Giorgi, Michelangelo Maestri, Melania Guida, Luca Carnicelli, Lorenzo Caciagli, Raffaele Ferri, Ubaldo Bonuccelli, Enrica Bonanni
PURPOSE: Sleep deprivation (SD) increases the occurrence of interictal epileptiform discharges (IED) compared to basal EEG in temporal lobe epilepsy (TLE). In adults, EEG after SD is usually performed in the morning after SD. We aimed to evaluate whether morning sleep after SD bears additional IED-inducing effects compared with nocturnal physiological sleep, and whether changes in sleep stability (described by the cyclic alternating pattern-CAP) play a significant role. METHODS: Adult patients with TLE underwent in-lab night polysomnography (n-PSG) and, within 7days from n-PSG, they underwent also a morning EEG after night SD (SD-EEG)...
June 17, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28633051/influence-of-lactic-acid-and-post-treatment-recovery-time-on-the-heat-resistance-of-listeria-monocytogenes
#8
Yasuo Omori, Kiyotaka Miake, Hiromi Nakamura, Eriko Kage-Nakadai, Yoshikazu Nishikawa
The aim of this study was to evaluate the effect of lactic acid (LA) with and without organic material at various post-treatment recovery times on the heat resistance of Listeria monocytogenes (Lm). LA decreased Lm numbers; however, the effect was remarkably attenuated by the presence of organic matter. Five strains of Lm were treated with LA and the listericidal effects were compared. The effect of LA varied depending on the strain, with ≥3.0% (w/w) LA required to kill the Lm strains in a short time. The heat resistance of Lm treated with LA was examined with respect to the time interval between the acid treatment and the subsequent manufacturing step...
June 12, 2017: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/28632902/impaired-hippocampal-glucose-metabolism-during-and-after-flurothyl-induced-seizures-in-mice-reduced-phosphorylation-coincides-with-reduced-activity-of-pyruvate-dehydrogenase
#9
Tanya S McDonald, Karin Borges
OBJECTIVE: To determine changes in glucose metabolism and the enzymes involved in the hippocampus ictally and postictally in the acute mouse flurothyl seizure model. METHODS: [U-(13) C]-Glucose was injected (i.p.) prior to, or following a 5 min flurothyl-induced seizure. Fifteen minutes later, mice were killed and the total metabolite levels and % (13) C enrichment were analyzed in the hippocampal formation using gas chromatography-mass spectrometry. Activities of key metabolic and antioxidant enzymes and the phosphorylation status of pyruvate dehydrogenase were measured, along with lipid peroxidation...
June 20, 2017: Epilepsia
https://www.readbyqxmd.com/read/28632542/creation-and-execution-of-a-novel-anesthesia-perioperative-care-service-at-a-veterans-affairs-hospital
#10
Bret D Alvis, Adam B King, Pratik P Pandharipande, Liza M Weavind, Katelin Avila, Philip J Leisy, Muhammad Ajmal, Michael McHugh, Kirk A Keegan, David A Baker, Ann Walia, Christopher G Hughes
Physician-led perioperative surgical home models are developing as a method for improving the American health care system. These models are novel, team-based approaches that help to provide continuity of care throughout the perioperative period. Another avenue for improving care for surgical patients is the use of enhanced recovery after surgery pathways. These are well-described methods that have shown to improve perioperative outcomes. An established perioperative surgical home model can help implementation, efficiency, and adherence to enhanced recovery after surgery pathways...
June 16, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28632248/perceived-benefits-and-barriers-to-exercise-for-recently-treated-adults-with-acute-leukemia
#11
Ashley Leak Bryant, AnnMarie L Walton, Mackenzi Pergolotti, Brett Phillips, Charlotte Bailey, Deborah K Mayer, Claudio Battaglini
PURPOSE/OBJECTIVES: To explore perceived exercise benefits and barriers in adults with acute leukemia who recently completed an inpatient exercise intervention during induction therapy.
. RESEARCH APPROACH: Descriptive, exploratory design using semistructured interviews.
. SETTING: Inpatient hematology/oncology unit at North Carolina Cancer Hospital in Chapel Hill.
. PARTICIPANTS: 6 adults with acute leukemia aged 35-67 years...
July 1, 2017: Oncology Nursing Forum
https://www.readbyqxmd.com/read/28632137/electrospun-silk-polyaniline-conduits-for-functional-nerve-regeneration-in-rat-sciatic-nerve-injury-model
#12
Suradip Das, Manav Sharma, Dhiren Saharia, Kushal Sarma, Elizabeth Muir, Utpal Bora
The present study describes the fabrication of polyaniline-silk fibroin nanocomposite based nerve conduits and its subsequent implantation in a rat sciatic nerve injury model for peripheral nerve regeneration. This is the first in vivo study of polyaniline based nerve conduit describing the safety and efficacy of the conduits in treating peripheral nerve injuries. The nanocomposite was synthesised by electrospinning a mixture of silk fibroin protein and polyaniline wherein the silk nanofibers were observed to be uniformly coated with polyaniline nanoparticles...
June 20, 2017: Biomedical Materials
https://www.readbyqxmd.com/read/28631842/uk-consensus-statement-on-the-use-of-plerixafor-to-facilitate-autologous-peripheral-blood-stem-cell-collection-to-support-high-dose-chemoradiotherapy-for-patients-with-malignancy
#13
Kenneth W Douglas, Maria Gilleece, Patrick Hayden, Hannah Hunter, Peter R E Johnson, Charlotte Kallmeyer, Ram K Malladi, Shankara Paneesha, Rachel Pawson, Michael Quinn, Kavita Raj, Deborah Richardson, Stephen Robinson, Nigel Russell, John Snowden, Anna Sureda, Eleni Tholouli, Kirsty Thomson, Mike Watts, Keith M Wilson
Plerixafor is a CXC chemokine receptor (CXCR4) antagonist that mobilizes stem cells in the peripheral blood. It is indicated (in combination with granulocyte-colony stimulating factor [G-CSF]) to enhance the harvest of adequate quantities of cluster differentiation (CD) 34+ cells for autologous transplantation in patients with lymphoma or multiple myeloma whose cells mobilize poorly. Strategies for use include delayed re-mobilization after a failed mobilization attempt with G-CSF, and rescue or pre-emptive mobilization in patients in whom mobilization with G-CSF is likely to fail...
June 20, 2017: Journal of Clinical Apheresis
https://www.readbyqxmd.com/read/28631256/vulnerability-to-a-metabolic-challenge-following-perinatal-asphyxia-evaluated-by-organotypic-cultures-neonatal-nicotinamide-treatment
#14
R Perez-Lobos, C Lespay-Rebolledo, A Tapia-Bustos, E Palacios, V Vío, D Bustamante, P Morales, M Herrera-Marschitz
The hypothesis of enhanced vulnerability following perinatal asphyxia was investigated with a protocol combining in vivo and in vitro experiments. Asphyxia-exposed (AS) (by 21 min water immersion of foetuses containing uterine horns) and caesarean-delivered control (CS) rat neonates were used at P2-3 for preparing triple organotypic cultures (substantia nigra, neostriatum and neocortex). At DIV 18, cultures were exposed to different concentrations of H2O2 (0.25-45 mM), added to the culture medium for 18 h...
June 19, 2017: Neurotoxicity Research
https://www.readbyqxmd.com/read/28630581/5000-meter-run-performance-is-not-enhanced-24-hrs-after-an-intense-exercise-bout-and-cold-water-immersion
#15
Mary C Stenson, Matthew R Stenson, Tracey D Matthews, Vincent J Paolone
Cold water immersion (CWI) is used by endurance athletes to speed recovery between exercise bouts, but little evidence is available on the effects of CWI on subsequent endurance performance. The purpose of this study was to investigate the effects of CWI following an acute bout of interval training on 5000 m run performance 24 hrs after interval training, perceived muscle soreness (PMS), range of motion (ROM), thigh circumference (TC), and perceived exertion (RPE). Nine endurance-trained males completed 2 trials, each consisting of an interval training session of 8 repetitions of 1200 m at a running pace equal to 75% of VO2peak, either a control or CWI treatment, and a timed 5000 m run 24 hrs post interval training session...
June 2017: Journal of Sports Science & Medicine
https://www.readbyqxmd.com/read/28630465/changes-in-pore-structure-of-coal-caused-by-coal-to-gas-bioconversion
#16
Rui Zhang, Shimin Liu, Jitendra Bahadur, Derek Elsworth, Yi Wang, Guanglong Hu, Yanna Liang
Microbial enhanced coalbed methane (ME-CBM) recovery is critically examined as a viable technology for natural gas recovery from coalbed methane (CBM) reservoirs. Since the majority of gas-in-place (GIP) is stored as an adsorbed phase in fine pores of coal matrix, the nano-pore structure directly influences gas storage and transport properties. Only limited studies have quantified the alteration of the nano-pore structure due to ME-CBM treatment. This study examines the evolution of the pore structure using a combination of small angle X-ray scattering (SAXS), low-pressure N2 and CO2 adsorption (LPGA) and high-pressure methane adsorption methods...
June 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28629938/poly-glycidyl-methacrylate-nanoparticle-coated-capillary-with-oriented-antibody-immobilization-for-immunoaffinity-in-tube-solid-phase-microextraction-preparation-and-characterization
#17
Ling-Ling Ying, Yuan-Chun Ma, Bei Xu, Xian-Hua Wang, Lin-Yi Dong, Dong-Mei Wang, Kun Liu, Liang Xu
A combination between modification with nanoparticles (NP) and oriented antibody immobilization (OAI) on the inner face of capillary was for the first time developed for immunoaffinity in-tube solid-phase microextraction (SPME) to promise high antigen extraction capacity. β2-microglobin (β2MG) and cystatin C (Cys-C) were selected as model antigens. Poly(glycidyl methacrylate) (PGMA) NPs were chemically immobilized onto the capillary by a ring-opening reaction. Antibodies for β2MG and Cys-C were immobilized on the NPs through OAI...
June 12, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28629709/energy-recovery-from-one-and-two-stage-anaerobic-digestion-of-food-waste
#18
Giorgia De Gioannis, Aldo Muntoni, Alessandra Polettini, Raffaella Pomi, Daniela Spiga
One- and two-stage anaerobic digestion of food waste aimed at recovering methane (CH4) and hydrogen and methane (H2+CH4), respectively, were compared in order to assess the potential benefits from the two-stage process in terms of overall energy recovery. Results suggest that a two-stage process where the first reactor is properly operated in order to achieve a significant net hydrogen production, may display a 20% comparatively higher energy recovery yield as a result, mainly, of enhanced methane production as well as of the associated hydrogen production...
June 16, 2017: Waste Management
https://www.readbyqxmd.com/read/28629589/physical-exercise-and-dna-injury-good-or-evil
#19
Elisa Danese, Giuseppe Lippi, Fabian Sanchis-Gomar, Giorgio Brocco, Manfredi Rizzo, Maciej Banach, Martina Montagnana
Regular, low-intensity physical activity is currently advocated for lowering the risk of developing many acute and especially chronic diseases. However, several lines of evidence attest that strenuous exercise may enhance inflammation and trigger the generation of free radical-mediated damage, thus overwhelming the undisputable benefits of regular, medium-intensity physical activity. Since reactive oxygen species are actively generated during high-intensity exercise, and these reactive compounds are known to impact DNA stability, we review here the current evidence about strenuous exercise and DNA injury...
2017: Advances in Clinical Chemistry
https://www.readbyqxmd.com/read/28629107/reducing-the-bioavailability-and-leaching-potential-of-lead-in-contaminated-water-hyacinth-biomass-by-phosphate-assisted-pyrolysis
#20
Lingna Shi, Lijun Wang, Tao Zhang, Jianfa Li, Xiaoyi Huang, Jing Cai, Jinhong Lü, Yue Wang
For the purpose of safe disposal of biomass contaminated by biosorption of heavy metals, phosphate-assisted pyrolysis of water hyacinth biomass contaminated by lead (Pb) was tried to reduce the bioavailability and leaching potential of Pb, using direct pyrolysis without additive as a control method. Direct pyrolysis of the contaminated biomass at low temperatures (300 and 400°C) could reduce the bioavailability of Pb, but the leaching potential of Pb was increased with the rising pyrolysis temperature. While phosphate-assisted pyrolysis significantly enhanced the recovery and stability of Pb in the char...
June 8, 2017: Bioresource Technology
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