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https://www.readbyqxmd.com/read/28383848/-how-i-treat%C3%A2-a-funnel-chest-with-computer-aided-design-cad
#1
N Wirtzfeld, J-P Chavoin, C Denoël
The contribution of computing in the management of patients with pectus excavatum has greatly improved the aesthetic result of the reconstruction endoprosthesis. Computer aided design (CAD) enables the design of implants perfectly suited to the deformation of the patient and avoids approximations of the traditional technique of plaster mold. Although this technique is applicable in many areas, this article will only deal with pectus excavatum.
October 2016: Revue Médicale de Liège
https://www.readbyqxmd.com/read/28379158/exome-sequencing-identified-a-novel-fbn2-mutation-in-a-chinese-family-with-congenital-contractural-arachnodactyly
#2
Guoling You, Bailing Zu, Bo Wang, Zhigang Wang, Yunlan Xu, Qihua Fu
Congenital contractural arachnodactyly (CCA) is an autosomal dominant disorder of connective tissue. CCA is characterized by arachnodactyly, camptodactyly, contrature of major joints, scoliosis, pectus deformities, and crumpled ears. The present study aimed to identify the genetic cause of a three-generation Chinese family with CCA. We successfully identified a novel missense mutation p.G1145D in the fibrillin-2 (FBN2) gene as the pathogenic mutation by whole exome sequencing (WES). The p.G1145D mutation occurs in the 12th calcium-binding epidermal growth factor-like (cbEGF) domain...
April 5, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28374301/periareolar-access-for-pectus-excavatum-correction-with-silicone-implants-a-new-method-to-minimize-postoperative-scars-review-of-the-literature-considerations-and-statistical-analysis-of-clinical-outcomes
#3
Alessandro Innocenti, Francesco Ciancio, Dario Melita, Mori Francesco, Aurelio Portincasa, Domenico Parisi, Emanuela Dreassi, Marco Innocenti
BACKGROUND: Pectus excavatum (PE) is one of the most frequent thoracic malformations. Generally, the malformation is not associated with functional disorders and often constitutes an aesthetic alteration with significant psychological distress. OBJECTIVES: To reduce the visibility of the residual scarring produced by corrective surgery and to improve the aesthetic outcome, the authors propose a new prosthetic implant technique through a periareolar access. METHODS: From January 2005 to January 2015, 11 patients affected with PE underwent the surgical procedure with a sternal prosthesis implanted through a periareolar access with the help of a fiberscope...
April 3, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28363366/minimal-invasive-repair-of-pectus-excavatum-and-carinatum
#4
REVIEW
Hans Pilegaard, Peter Bjørn Licht
Minimal invasive surgery has become the gold standard for surgical repair of pectus excavatum. The procedure can be performed as fast-track surgery and cosmetic results are excellent. In addition, cardiac performance improves after correction. With increased awareness on the Internet, the number of patients who seek help continues to rise, primarily for cosmetic reasons. Pectus carinatum is much less frequent than pectus excavatum. Over the past decade surgery has largely been replaced by compression techniques that use a brace, and cosmetic results are good...
May 2017: Thoracic Surgery Clinics
https://www.readbyqxmd.com/read/28342579/magnetic-mini-mover-procedure-for-pectus-excavatum-iv-fda-sponsored-multicenter-trial
#5
Claire E Graves, Shinjiro Hirose, Gary W Raff, Corey W Iqbal, Jill Imamura-Ching, Darrell Christensen, Richard Fechter, Dillon Kwiat, Michael R Harrison
PURPOSE: The Magnetic Mini-Mover Procedure (3MP) is a minimally invasive treatment for prepubertal patients with pectus excavatum. This multicenter trial sought to supplement safety and efficacy data from an earlier pilot trial. METHODS: Fifteen patients with pectus excavatum had a titanium-enclosed magnet implanted on the sternum. Externally, patients wore a custom-fitted magnetic brace. Patients were monitored closely for safety. Efficacy was determined by the Haller Index (HI) and satisfaction surveys...
March 15, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28341230/intraoperative-cryoanalgesia-for-managing-pain-after-the-nuss-procedure
#6
Claire Graves, Olajire Idowu, Sang Lee, Benjamin Padilla, Sunghoon Kim
BACKGROUND: Cryoanalgesia prevents pain by freezing the affected peripheral nerve. We report the use of intraoperative cryoanalgesia during the Nuss procedure for pectus excavatum and describe our initial experience, modifications of technique, and lessons learned. MATERIALS AND METHODS: We retrospectively reviewed the medical records of patients who received cryoanalgesia during the Nuss procedure between June 1, 2015, and April 30, 2016, at our institutions and analyzed modifications in surgical technique during this early adoption period...
March 16, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28329150/scoliosis-after-pectus-excavatum-correction-does-it-improve-or-worsen-%C3%A2
#7
Jae Ho Chung, Hyung Joo Park, Kwang Taik Kim
OBJECTIVES: Scoliosis is associated with pectus excavatum. However, the change in the degree of scoliosis after pectus excavatum correction has not been clarified. This study examined how the correction of pectus excavatum influences the status of pre-existing scoliosis. METHODS: A total of 779 pectus excavatum patients operated between 2007 and 2011 using the pectus bar were retrospectively analysed. Preoperative severity and postoperative change of scoliosis in accordance with the severity of pectus excavatum were evaluated...
March 7, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28321340/right-ventricular-compression-mimicking-brugada-like-electrocardiogram-in-a-patient-with-recurrent-pectus-excavatum
#8
Jinhee Ahn, Jong-Il Choi, Jaemin Shim, Sung Ho Lee, Young-Hoon Kim
Pectus excavatum (PE), the most common skeletal anomaly of chest wall, sometimes requires a surgical correction but recurrent PE is not uncommon. PE usually has a benign course; however, this chest deformity may be associated with symptomatic tachyarrhythmias due to mechanical compression. We report a case of a patient with recurrent PE after surgical correction presenting with palpitation and electrocardiogram (ECG) showing ST-segment elevation on the right precordial leads, which could be mistaken for a Brugada syndrome (BrS)...
2017: Case Reports in Cardiology
https://www.readbyqxmd.com/read/28317635/a-depressed-heart-atrial-fibrillation-and-pulmonary-hypertension-in-severe-pectus-excavatum
#9
Sumit Som, Tatyana Danilov
No abstract text is available yet for this article.
April 2017: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/28274516/the-dynamic-compression-brace-for-pectus-carinatum-intermediate-results-in-286-patients
#10
Sjoerd A de Beer, Martin Gritter, Justin R de Jong, Ernst L W van Heurn
BACKGROUND: Dynamic brace compression is a novel treatment for patients with pectus carinatum. The dynamic compression system contains a device to measure the flexibility of the thoracic wall and regulate the pressure of the brace. METHODS: Patients referred to our pediatric surgical center were screened for treatment with the dynamic compression brace. Patients with a pressure of initial correction (PIC) of 10.0 pounds per square inch or less were offered treatment with the brace...
March 5, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28260191/routine-use-of-chest-radiographs-in-the-post-operative-management-of-pectus-bar-removal-necessity-or-futility
#11
Ashwini Suresh Poola, Rebecca M Rentea, Katrina L Weaver, Shawn David St Peter
BACKGROUND: While there is literature on techniques for pectus bar removal, there are limited reports on post-operative management. This can include obtaining a postoperative chest radiograph (CXR) despite the minimal risk of associated intra-thoracic complications. This is a review of our experience with bar removal and lack of routine post-operative CXR. METHODS: A single institution retrospective chart review was performed from 2000 to 2015. Patients who underwent a pectus bar removal procedure were included...
March 4, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/28230898/manifestations-and-medicolegal-significance-of-loeys-dietz-syndrome
#12
Roger W Byard
Loeys-Dietz syndrome is a recently described autosomal dominant disorder with underlying vasculopathy characterized by aortic and other vascular aneurysmal dissection/rupture. A 61-year-old man is reported who died suddenly and unexpectedly and at autopsy was found to have a ruptured abdominal aortic aneurysm. Additional findings included dolichostenomelia, high-arched palate, and pectus excavatum. There was a strong family history of Loeys-Dietz syndrome, although the decedent had never been tested. Death was, therefore, due to a ruptured abdominal aortic aneurysm in a case of probable Loeys-Dietz syndrome...
February 23, 2017: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/28230518/pectus-excavatum-first-ultrastructural-findings-of-a-potential-ciliopathy
#13
Christoph Brochhausen, Andreas Mamilos, Salmai Turial, C James Kirkpatrick
No abstract text is available yet for this article.
January 2017: Ultrastructural Pathology
https://www.readbyqxmd.com/read/28217231/successful-intermuscular-implantation-of-subcutaneous-implantable-cardioverter-defibrillator-in-a-japanese-patient-with-pectus-excavatum
#14
Yusuke Kondo, Marehiko Ueda, Joachim Winter, Miyo Nakano, Masahiro Nakano, Masayuki Ishimura, Kazuo Miyazawa, Kaoru Tateno, Yoshio Kobayashi
The entirely subcutaneous implantable cardioverter-defibrillator (ICD) system was developed to provide a life-saving defibrillation therapy that does not affect the heart and vasculature. The subcutaneous ICD is preferred over the transvenous ICD for patients with a history of recurrent infection presenting major life-threatening rhythms. In this case report, we describe the first successful intermuscular implantation of a completely subcutaneous ICD in a Japanese patient with pectus excavatum. There were no associated complications with the device implantation or lead positioning...
February 2017: Journal of Arrhythmia
https://www.readbyqxmd.com/read/28214505/positional-right-ventricular-obstruction-in-pectus-excavatum
#15
Katherine Underwood, Matthew Vorsanger, Muhamed Saric, Adam H Skolnick
Pectus excavatum is one of the most common congenital chest wall deformities. The degree of sternal depression, which may result in compression of the right heart by the chest wall, is variable. While typically asymptomatic, there are various symptoms that can result from severe pectus excavatum. We report on a patient with severe pectus excavatum leading to dynamic obstruction of the right ventricular outflow tract in the seated position.
April 15, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28202768/respiratory-morbidity-in-infants-born-with-a-congenital-lung-malformation
#16
Celine Delestrain, Naziha Khen-Dunlop, Alice Hadchouel, Pierrick Cros, Héloïse Ducoin, Michael Fayon, Isabelle Gibertini, André Labbé, Géraldine Labouret, Marie-Noëlle Lebras, Guillaume Lezmi, Fouad Madhi, Guillaume Thouvenin, Caroline Thumerelle, Christophe Delacourt
BACKGROUND AND OBJECTIVES: The actual frequency of respiratory symptoms related to congenital pulmonary malformations (CPMs) remains undetermined. The goal of this study was to prospectively evaluate the respiratory symptoms occurring in infants with prenatally diagnosed CPMs, identify factors associated with the occurrence of these symptoms, and evaluate their resolution after surgery. METHODS: Infectious and noninfectious respiratory symptoms were prospectively collected in a French multicenter cohort of children with CPMs...
February 15, 2017: Pediatrics
https://www.readbyqxmd.com/read/28196662/a-less-intensive-bracing-protocol-for-pectus-carinatum
#17
George Wahba, Ahmed Nasr, Marcos Bettolli
OBJECTIVES: Despite the widespread use of bracing to correct Pectus carinatum (PC) there is no consensus in the number of hours per day patients are instructed to wear the brace. In our practice, we use a less rigorous protocol of 8-12h/day. We sought to evaluate our results and those in the literature to determine whether more intensive usage is necessary. STUDY DESIGN: We reviewed the outcomes of patients with PC treated at our institution between 2012 and 2015...
January 31, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28163941/novel-pathogenic-variant-in-tgfbr2-confirmed-by-molecular-modeling-is-a-rare-cause-of-loeys-dietz-syndrome
#18
Michael T Zimmermann, Raul A Urrutia, Patrick R Blackburn, Margot A Cousin, Nicole J Boczek, Eric W Klee, Colleen Macmurdo, Paldeep S Atwal
Loeys-Dietz syndrome (LDS) is a connective tissue disorder characterized by vascular findings of aneurysm and/or dissection of cerebral, thoracic, or abdominal arteries and skeletal findings. We report a case of a novel pathogenic variant in TGFBR2 and phenotype consistent with classic LDS. The proband was a 10-year-old presenting to the genetics clinic with an enlarged aortic root (Z-scores 5-6), pectus excavatum, and congenital contractures of the right 2nd and 3rd digit. Molecular testing of TGFBR2 was sent to a commercial laboratory and demonstrated a novel, likely pathogenic, variant in exon 4, c...
2017: Case Reports in Genetics
https://www.readbyqxmd.com/read/28140622/exaggerated-interventricular-dependence-among-patients-with-pectus-excavatum-combined-assessment-with-cardiac-mri-and-chest-ct
#19
Alejandro Deviggiano, Javier Vallejos, Natalia Vina, Marcelo Martinez-Ferro, Gaston Bellia-Munzon, Patricia Carrascosa, Gaston A Rodríguez-Granillo
OBJECTIVE: We sought to explore whether patients with pectus excavatum have exaggerated interventricular dependence and to evaluate the impact of the malformation severity (assessed on CT) on both anatomic and functional cardiac parameters (assessed on cardiac MRI). SUBJECTS AND METHODS: The current study involved consecutive patients with a diagnosis of pectus excavatum who were referred to undergo cardiac MRI and chest CT to establish surgical candidacy or to define treatment strategies...
April 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28134952/pectus-excavatum-a-review-of-diagnosis-and-current-treatment-options
#20
Irfaan Abid, MennatAllah M Ewais, Joseph Marranca, Dawn E Jaroszewski
Osteopathic medicine places a special emphasis on the musculoskeletal system, and understanding how chest wall structure may influence function is critical. Pectus excavatum is a common congenital chest wall defect in which the sternum is depressed posteriorly. Patients may present with complaints of chest wall discomfort, exercise intolerance, and tachycardia. The medical implications, diagnosis, and treatment options for patients with pectus excavatum are reviewed.
February 1, 2017: Journal of the American Osteopathic Association
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