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Abdominal Obesity

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https://www.readbyqxmd.com/read/29790467/prevalence-of-abdominal-obesity-and-excess-weight-among-portuguese-children-and-why-abdominal-obesity-should-be-included-in-clinical-practice
#1
Daniela Rodrigues, Cristina Padez, Aristides M Machado-Rodrigues
INTRODUCTION: Central adiposity in children has increased to a higher degree than general adiposity however it is not a routine measurement in clinical practice. We aimed to estimate the prevalence of overweight, obesity, and abdominal fat distribution and observe the prevalence of abdominal obesity among non-obese 6-10-year-old children. MATERIAL AND METHODS: Weight, height, and waist circumference were measured in a sample of 793 children (408 girls). International Obesity Task Force cut-offs were used to define overweight and obesity...
March 29, 2018: Acta Médica Portuguesa
https://www.readbyqxmd.com/read/29789994/performance-evaluation-of-a-semi-automated-method-for-18-f-fdg-uptake-in-abdominal-visceral-adipose-tissue
#2
Stefanie A de Boer, Daan S Spoor, Riemer H J A Slart, Douwe J Mulder, Melanie Reijrink, Ronald J H Borra, Gerbrand M Kramer, Otto S Hoekstra, Ronald Boellaard, Marcel J Greuter
PURPOSE: Severity of abdominal obesity and possibly levels of metabolic activity of abdominal visceral adipose tissue (VAT) are associated with an increased risk for cardiovascular disease (CVD). In this context, the purpose of the current study was to evaluate the reproducibility and repeatability of a semi-automated method for assessment of the metabolic activity of VAT using 2-deoxy-2-[18 F]fluoro-D-glucose ([18 F]FDG) positron emission tomography (PET)/x-ray computed tomography (CT)...
May 22, 2018: Molecular Imaging and Biology: MIB: the Official Publication of the Academy of Molecular Imaging
https://www.readbyqxmd.com/read/29786471/the-effects-of-polyphenol-supplementation-on-adipose-tissue-morphology-and-gene-expression-in-overweight-and-obese-humans
#3
Jasper Most, Ines Warnke, Mark V Boekschoten, Johan W E Jocken, Philip de Groot, Angelika Friedel, Igor Bendik, Gijs H Goossens, Ellen E Blaak
Dietary polyphenols have beneficial effects on adipose tissue mass and function in rodents, but human studies are scarce. In a randomized, placebo-controlled study, 25 (10 women) overweight and obese humans received a combination of the polyphenols epigallocatechin-gallate and resveratrol (282 mg/d, 80 mg/d, respectively, EGCG+RES, n = 11) or placebo (PLA, n = 14) supplementation for 12 weeks. Abdominal subcutaneous adipose tissue (SAT) biopsies were collected for assessment of adipocyte morphology and micro-array analysis...
May 1, 2018: Adipocyte
https://www.readbyqxmd.com/read/29785272/abdominal-obesity-in-type-1-diabetes-associated-with-gender-cardiovascular-risk-factors-and-complications-and-difficulties-achieving-treatment-targets-a-cross-sectional-study-at-a-secondary-care-diabetes-clinic
#4
Eva O Melin, Hans O Thulesius, Magnus Hillman, Mona Landin-Olsson, Maria Thunander
Background: Abdominal obesity is linked to cardiovascular diseases in type 1 diabetes (T1D). The primary aim was to explore associations between abdominal obesity and cardiovascular complications, metabolic and inflammatory factors. The secondary aim was to explore whether achieved recommended treatment targets differed between the obese and non-obese participants. Methods: Cross sectional study of 284 T1D patients (age 18-59 years, men 56%), consecutively recruited from one secondary care specialist diabetes clinic in Sweden...
2018: BMC Obesity
https://www.readbyqxmd.com/read/29783856/increased-aqp7-abundance-in-skeletal-muscle-from-obese-men-with-type-2-diabetes
#5
Janne Lebeck, Esben Søndergaard, Søren Nielsen
AQP7 facilitates the transport of glycerol across cell membranes. In mice, fasting and refeeding regulate adipose tissue AQP7 abundance and a role in controlling triglyceride accumulation in adipose tissue has been proposed. AQP7 is also expressed in skeletal muscle, where its function remains to be determined. Here, the abundance of AQP7 in abdominal subcutaneous adipose tissue (SAT) and skeletal muscle was evaluated in the overnight fasted and postprandial state in eight lean and eight obese men with type 2 diabetes (T2D)...
May 21, 2018: American Journal of Physiology. Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29783248/-features-of-the-course-of-irritable-bowel-syndrome-in-patients-with-excess-body-weight
#6
Mykola A Bychkov, Iryna M Ferents
OBJECTIVE: Introduction: Currently, the diagnosis of irritable bowel syndrome (IBS) is only based on clinical symptoms without clear interpretation and can be interpreted differently, complicating the diagnosis. Therefore, to study features of the prevalence and the course of IBS in patients with excessive body weight / obesity is of particular significance nowadays. The aim of the research is to evaluate the prevalence and the course of IBS in patients with obesity. PATIENTS AND METHODS: Materials and methods: Observation results for 120 obese persons who underwent in-patient treatment at various hospital departments in Western Ukraine have been analyzed to evaluate the prevalence of IBS...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29782075/the-mediating-effects-of-gestational-diabetes-on-fetal-growth-and-adiposity-in-women-who-are-overweight-and-obese-secondary-analysis-of-the-limit-randomised-trial
#7
Amanda J Poprzeczny, Jennie Louise, Andrea R Deussen, Jodie M Dodd
OBJECTIVE: to describe the mediating effect of maternal gestational diabetes on fetal biometry and adiposity measures among overweight or obese pregnant women. DESIGN: Secondary analysis of the LIMIT randomised trial. SETTING: Public hospitals, metropolitan Adelaide, South Australia. POPULATION: Pregnant women with body mass index (BMI) ≥25 kg/m2 , and singleton gestation. METHODS: Fetal ultrasound measures at 36 weeks' gestation and baseline BMI from women randomised to the LIMIT trial Standard Care group (n = 912 women) were used to conduct causal mediation analyses using regression-based methods...
May 21, 2018: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29781162/predictors-of-ultrasound-failure-to-detect-hepatocellular-carcinoma
#8
Mariya L Samoylova, Neil Mehta, John P Roberts, Francis Y Yao
Current guidelines recommend ultrasound (US) for hepatocellular carcinoma (HCC) surveillance in cirrhosis. We assess predictors of decreased US sensitivity for detecting HCC. At a single U.S. center, all HCC patients evaluated for liver transplant (LT) receive an abdominal US. In consecutive patients presenting 2007-2015, untreated lesions found on CT/MRI within 3 months of US were compared with US findings. Multivariable logistic regression models compared US sensitivities by patient characteristics. Of 1008 patients completing LT evaluation, 47...
May 21, 2018: Liver Transplantation
https://www.readbyqxmd.com/read/29779486/risk-factors-for-prolonged-postoperative-ileus-in-adult-patients-undergoing-elective-colorectal-surgery-an-observational-cohort-study
#9
Andrea Pisani Ceretti, Nirvana Maroni, Marco Longhi, Marco Giovenzana, Roberto Santambrogio, Matteo Barabino, Carmelo Luigiano, Giovanni Radaelli, Enrico Opocher
Purpose Prolonged postoperative ileus (PPOI) after abdominal surgery may effect unfavourably the patient recovery. The aim of this study was to estimate the incidence of PPOI in patients elective for colorectal resection and investigate perioperative variables associated with PPOI. Methods A consecutive series of 428 patients undergoing colorectal resection (median age 72, range 24-92, years; men/women ratio 1.14) were analyzed. Data were extracted retrospectively throughout a five-year period from an electronic prospectively maintained database...
May 20, 2018: Reviews on Recent Clinical Trials
https://www.readbyqxmd.com/read/29778565/effect-of-intermittent-versus-continuous-energy-restriction-on-weight-loss-maintenance-and-cardiometabolic-risk-a-randomized-1-year-trial
#10
T M Sundfør, M Svendsen, S Tonstad
BACKGROUND & AIMS: Long-term adherence to conventional weight-loss diets is limited while intermittent fasting has risen in popularity. We compared the effects of intermittent versus continuous energy restriction on weight loss, maintenance and cardiometabolic risk factors in adults with abdominal obesity and ≥1 additional component of metabolic syndrome. METHODS & RESULTS: In total 112 participants (men [50%] and women [50%]) aged 21-70 years with BMI 30-45 kg/m2 (mean 35...
March 29, 2018: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/29778507/factors-associated-with-outcomes-and-inpatient-90-day-cost-of-care-in-endometrial-cancer-patients-undergoing-hysterectomy-implications-for-bundled-care-payments
#11
Aimee Rolston, Ryan J Spencer, R Kevin Reynolds, Laurel W Rice, Shitanshu Uppal
OBJECTIVE: To investigate the association of obesity and other comorbidities as well as route of surgery with postoperative outcomes, as well as 30- and 90-day inpatient cost of care after hysterectomy for endometrial cancer. METHODS: From the 2013 National Readmission Database release, patients who underwent hysterectomy for endometrial cancer were included. Obesity was classified as non-obese (body mass index [BMI] < 35 kg/m2 ); class I/II obesity (BMI ≥ 35 but <40 kg/m2 and without obesity related medical condition qualifying it as morbid obesity), class III obesity (BMI ≥ 40 kg/m2 OR BMI ≥ 35 kg/m2 with an obesity-related medical condition)...
May 16, 2018: Gynecologic Oncology
https://www.readbyqxmd.com/read/29777226/genetic-contribution-to-waist-to-hip-ratio-in-mexican-children-and-adolescents-based-on-12-loci-validated-in-european-adults
#12
Michelle Turcotte, Arkan Abadi, Jesus Peralta-Romero, Fernando Suarez, Hudson Reddon, Jaime Gomez-Zamudio, Ana I Burguete-Garcia, Miguel Cruz, David Meyre
BACKGROUND/OBJECTIVES: The prevalence of abdominal obesity in Mexican children has risen dramatically in the past decade. Genome-wide association studies (GWAS) for waist-to-hip ratio (WHR) performed predominantly in European descent adult  populations have identified multiple single-nucleotide polymorphisms (SNPs) with larger effects in women. The contribution of these SNPs to WHR in non-European children is unknown. SUBJECTS/METHODS: Mexican children and adolescents (N = 1421, 5-17 years) were recruited in Mexico City...
March 13, 2018: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/29773491/association-between-number-of-preventive-care-guidelines-and-preventive-care-utilization-by-patients
#13
Glen B Taksler, Elizabeth R Pfoh, Kurt C Stange, Michael B Rothberg
INTRODUCTION: The number of preventive care guidelines is rapidly increasing. It is unknown whether the number of guideline-recommended preventive services is associated with utilization. METHODS: The authors used Poisson regression of 390,778 person-years of electronic medical records data from 2008 to 2015, in 80,773 individuals aged 50-75 years. Analyses considered eligibility for 11 preventive services most closely associated with guidelines: tobacco cessation; control of obesity, hypertension, lipids, or blood glucose; influenza vaccination; and screening for breast, cervical, or colorectal cancers, abdominal aortic aneurysm, or osteoporosis...
May 8, 2018: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/29772477/depression-and-metabolic-syndrome-in-the-older-population-a-review-of-evidence
#14
REVIEW
Nikolena Repousi, Maria F Masana, Albert Sanchez-Niubo, Josep Maria Haro, Stefanos Tyrovolas
BACKGROUND: Metabolic syndrome (MetS) has been shown to be associated with depression in older adults but the results are mixed. We summarized and evaluated the association between depression and MetS in people aged 60 years or over. METHODS: Relevant published studies from January 1997 to July 2017 were identified by searching two electronic databases: PubMed/Medline and EMBASE. Observational studies were considered. RESULTS: Twelve studies were included in the systematic review...
April 22, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29772029/prolyl-carboxypeptidase-activity-in-the-circulation-and-its-correlation-with-body-weight-and-adipose-tissue-in-lean-and-obese-subjects
#15
Kaat Kehoe, Heidi Noels, Wendy Theelen, Emilie De Hert, Shenguan Xu, An Verrijken, Thierry Arnould, Erik Fransen, Nina Hermans, Anne-Marie Lambeir, Per Venge, Luc Van Gaal, Ingrid De Meester
BACKGROUND: Prolyl carboxypeptidase (PRCP) is involved in the regulation of body weight, likely by hydrolysing alpha-melanocyte-stimulating hormone and apelin in the hypothalamus and in the periphery. A link between PRCP protein concentrations in plasma and metabolic disorders has been reported. In this study, we investigated the distribution of circulating PRCP activity and assessed its relation with body weight and adipose tissue in obese patients and patients who significantly lost weight...
2018: PloS One
https://www.readbyqxmd.com/read/29772027/association-between-different-combination-of-measures-for-obesity-and-new-onset-gallstone-disease
#16
Tong Liu, Wanchao Wang, Yannan Ji, Yiming Wang, Xining Liu, Liying Cao, Siqing Liu
BACKGROUND: Body mass index(BMI) is a calculation index of general obesity. Waist circumference(WC) is a measure of body-fat distribution and always used to estimate abdominal obesity. An important trait of general obesity and abdominal obesity is their propensity to coexist. Using one single measure of obesity could not estimate persons at risk for GSD precisely. OBJECTIVES: This study aimed to compare the predictive values of various combination of measures for obesity(BMI, WC, waist to hip ratio) for new-onset GSD...
2018: PloS One
https://www.readbyqxmd.com/read/29770281/intestinal-spirochetosis-in-an-immunocompetent-patient
#17
Patricia Guzman Rojas, Jelena Catania, Jignesh Parikh, Tran C Phung, Glenn Speth
Intestinal spirochetosis (IS) is an infestation defined by the presence of spirochetes on the surface of the colonic mucosa. The implicated organisms can be Brachyspira aalborgi or Brachyspira pilosicoli . We present the case of a 66-year-old man with a past medical history of diabetes mellitus, hypertension, morbid obesity, and gastroesophageal reflux. The patient was sent to the gastroenterology clinic for a screening colonoscopy due to a prior history of colonic polyps. The patient was completely asymptomatic as he denies any abdominal pain, diarrhea, melena, or hematochezia...
March 15, 2018: Curēus
https://www.readbyqxmd.com/read/29770221/risperidone-induced-type-2-diabetes-presenting-with-diabetic-ketoacidosis
#18
Clarissa Ern Hui Fang, Mohammed Faraz Rafey, Aine Cunningham, Sean F Dinneen, Francis M Finucane
A 28-year-old male presented with 2 days of vomiting and abdominal pain, preceded by 2 weeks of thirst, polyuria and polydipsia. He had recently started risperidone for obsessive-compulsive disorder. He reported a high dietary sugar intake and had a strong family history of type 2 diabetes mellitus (T2DM). On admission, he was tachycardic, tachypnoeic and drowsy with a Glasgow Coma Scale (GCS) of 10/15. We noted axillary acanthosis nigricans and obesity (BMI 33.2 kg/m2 ). Dipstick urinalysis showed ketonuria and glycosuria...
2018: Endocrinology, Diabetes & Metabolism Case Reports
https://www.readbyqxmd.com/read/29770188/retrograde-jejunojejunal-intussusception-in-a-pregnant-female-after-laparoscopic-roux-en-y-gastric-bypass
#19
Khuram Khan, Saqib Saeed, Amrita Persaud, Mohammad Sbeih, Sanjiv Gray, Leaque Ahmed
Adult intussusception is a rare complication after laparoscopic Roux-En-Y gastric bypass (LRYGB) surgery. Incidence of intussusception is on the rise as the demand of bariatric surgeries is increased to treat morbid obesity. Among the bariatric surgeries, LRYGB gastric bypass results in significantly higher weight loss with thinning of the mesentery resulting in increased risk for intussusception. Majority of intussusception cases after gastric bypass have been reported in non-pregnant patients. We report a case of retrograde jejunojejunal intussusception in 6 weeks pregnant female following laparoscopic gastric bypass, which was diagnosed with abdominal magnetic resonance imaging and managed successfully with resection and revision of the anastomosis...
May 2018: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/29768581/built-environment-contextual-income-and-obesity-in-older-adults-evidence-from-a-population-based-study
#20
Carolina Abreu Henn de Araújo, Maruí W Corseuil Giehl, Ana Lúcia Danielewicz, Pierre Guedes de Araujo, Eleonora d'Orsi, Antonio Fernando Boing
The objective was to verify the association between built environment, contextual income, and obesity in older adults in Florianópolis, Santa Catarina State, Brazil. This was a cross-sectional study in a sample of 1,197 older people (≥ 60 years) evaluated in the EpiFloripa Older Adults Cohort in 2013/2014. The outcomes were overall obesity, abdominal obesity, waist circumference (WC), and body mass index (BMI). Contextual income in the census tract and characteristics of the built environment were analyzed using data from the Florianópolis Institute of Urban Planning (IPUF) and the 2010 Population Census...
May 10, 2018: Cadernos de Saúde Pública
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