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https://www.readbyqxmd.com/read/28899875/stridor-is-not-always-croup-infantile-haemangioma-in-the-airway
#1
Joana Cunha Oliveira, Inês Azevedo, Augusta Gonçalves, Carla Moreira
No abstract text is available yet for this article.
September 12, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28893261/a-tale-of-two-systems-practice-patterns-of-a-single-group-of-emergency-medical-physicians-in-taiwan-and-china
#2
I-Anne Huang, Tang-Her Jaing, Chang-Teng Wu, Chee-Jen Chang, Shan-Hsuan Hsia, Nicole Huang
BACKGROUND: The quality of pediatric emergency care has been a major concern in health care. Following a series of health system reforms in China, it is important to do this assessment of pediatric emergency care, and to explore potential influences of health care system. This study aimed to compare practice differences in treating children with respiratory illnesses in two emergency department (ED) settings within different health care systems: China and Taiwan. METHODS: A pooled cross-sectional hospital-based study was conducted in two tertiary teaching hospitals in Xiamen, China and Keelung, Taiwan belong to the same hospital chain group...
September 11, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28858086/association-of-croup-with-asthma-in-children-a-cohort-study
#3
Sheng-Chieh Lin, Hui-Wen Lin, Bor-Luen Chiang
Asthma and croup are common inflammatory airway diseases involving the bronchus in children. However, no study has reported the effects of urbanization, sex, age, and bronchiolitis on the association of croup and its duration with asthma development. We used the Taiwan Longitudinal Health Insurance Database (LHID) to perform this population-based cohort study; here, the cluster effect caused by hospitalization was considered to evaluate the association between croup and asthma development and the risk factors for asthma in children of different age groups...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28835504/attenuated-human-parainfluenza-virus-type-1-hpiv1-expressing-the-respiratory-syncytial-virus-rsv-fusion-f-glycoprotein-from-an-added-gene-effects-of-pre-fusion-stabilization-and-packaging-of-rsv-f
#4
Xiang Liu, Bo Liang, Joan Ngwuta, Xueqiao Liu, Sonja Surman, Matthias Lingemann, Peter D Kwong, Barney S Graham, Peter L Collins, Shirin Munir
Human respiratory syncytial virus (RSV) is the most prevalent worldwide cause of severe respiratory tract infection in infants and young children. Human parainfluenza virus type 1 (HPIV1) also causes severe pediatric respiratory illness, especially croup. Both viruses lack vaccines. Here, we describe the preclinical development of a bivalent RSV/HPIV1 vaccine based on a recombinant HPIV1 vector, attenuated by a stabilized mutation, that expresses RSV F protein modified for increased stability in the pre-fusion (pre-F) conformation by previously-described disulfide bond (DS) and hydrophobic cavity-filling (Cav1) mutations...
August 23, 2017: Journal of Virology
https://www.readbyqxmd.com/read/28831577/chest-radiographic-features-of-human-metapneumovirus-infection-in-pediatric-patients
#5
Melissa A Hilmes, F Daniel Dunnavant, Sudha P Singh, Wendy D Ellis, Daniel C Payne, Yuwei Zhu, Marie R Griffin, Kathryn M Edwards, John V Williams
BACKGROUND: Human metapneumovirus (HMPV) was identified in 2001 and is a common cause of acute respiratory illness in young children. The radiologic characteristics of laboratory-confirmed HMPV acute respiratory illness in young children have not been systematically assessed. OBJECTIVE: We systematically evaluated the radiographic characteristics of acute respiratory illness associated with HMPV in a prospective cohort of pediatric patients. MATERIALS AND METHODS: We included chest radiographs from children <5 years old with acute respiratory illness who were enrolled in the prospective New Vaccine Surveillance Network (NVSN) study from 2003 to 2009 and were diagnosed with HMPV by reverse transcription-polymerase chain reaction (RT-PCR)...
August 22, 2017: Pediatric Radiology
https://www.readbyqxmd.com/read/28816002/maternal-body-mass-index-relation-with-infant-respiratory-symptoms-and-infections
#6
Ashley Rajappan, Anna Pearce, Hazel M Inskip, Janis Baird, Sarah R Crozier, Cyrus Cooper, Keith M Godfrey, Graham Roberts, Jane S A Lucas, Katharine C Pike
BACKGROUND: Maternal obesity is increasingly prevalent in many westernized countries. Many studies report associations between maternal obesity and childhood wheeze or asthma but few have considered maternal obesity in relation to respiratory infections or symptoms other than wheeze during infancy. This study assesses the relationship between maternal BMI and reported wheeze, cough and respiratory infections during the first year of life. METHODS: In 2799 mother-child pairs, we examined the relations between maternal pre-pregnancy BMI and pregnancy weight gain and reported offspring wheeze, prolonged cough, lower respiratory tract infection, croup, and ear infection before age 1 year, along with reported diarrhea or vomiting...
August 16, 2017: Pediatric Pulmonology
https://www.readbyqxmd.com/read/28777267/mistaken-identity-asthma-and-croup-in-a-previously-healthy-9-year-old-male
#7
Sylvia Owusu-Ansah, Oluwakemi Badaki-Makun, Thuy L Ngo
Cough is one of the most common presenting complaints encountered in primary care settings and the emergency department. In 2010, the Centers for Disease Control and Prevention reported approximately 31 million visits to ambulatory care centers for cough, making cough the most frequent presenting complaint in ambulatory visits (2010 National Ambulatory Medical Care Survey). Significant causes of cough can often be overlooked because it is a common symptom of a myriad of pathologies. We report the case of an otherwise healthy 9-year-old male who presented with worsening cough over a month and a half, subsequently noted to have a mediastinal mass, and diagnosed with lymphoma...
August 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/28757139/clinical-and-epidemiological-characteristics-of-human-parainfluenza-virus-infections-of-children-in-southern-taiwan
#8
Kai-Wen Wu, Shih-Min Wang, Ching-Fen Shen, Tzong-Shiann Ho, Jen-Ren Wang, Ching-Chuan Liu
BACKGROUND: Human parainfluenza viruses (HPIV) 1-4 had been analyzed as being one of the most frequent causes of hospitalizations for young children with respiratory tract illnesses. METHODS: This retrospective study was performed from children virologically confirmed as HPIV infection through throat swab or nasopharyngeal aspirates at a tertiary care university hospital, between January 2012 and December 2014. HPIV4 was not checked and analyzed, due to not include in the commercial kit...
June 22, 2017: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://www.readbyqxmd.com/read/28735259/observational-study-on-the-palatability-and-tolerability-of-oral-prednisolone-and-oral-dexamethasone-in-children-in-saudi-arabia-and-the-uk
#9
Fahad Aljebab, Mofadhi Alanazi, Imti Choonara, Sharon Conroy
BACKGROUND: Short-course oral corticosteroids are routinely used to treat acute asthma and croup. We evaluated their tolerability and palatability in Saudi Arabian (SA) and UK children. METHODS: Prospective observational/interview study (3 months in each country). Palatability was evaluated using a 5-point facial Hedonicscale and tolerability by direct questioning of patient/parents. RESULTS: In SA, of 122 patients (2-10 years) recruited, 52 received prednisolone base tablets, 37 prednisolone sodium phosphate syrup and 33 received dexamethasone elixir...
July 22, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28696771/occurrence-of-wounds-in-nigerian-horses
#10
Onyinyechukwu A Agina, John I Ihedioha
This study investigated the occurrence of wounds in Nigerian horses. The study population was 1,621 horses sold at the Obollo Afor horse lairage in Enugu State, Nigeria, during a 6-month period: 3 months of dry season and 3 months of rainy season (February-April and June-August 2012). A total of 207 horses were systematically sampled and subjected to a comprehensive physical examination. Those with wounds were marked, recorded, and clinically examined. Of the 207 horses sampled, 21 (10.1%) had wounds. The body distribution of the wounds was 9...
October 2017: Journal of Applied Animal Welfare Science: JAAWS
https://www.readbyqxmd.com/read/28622285/what-is-the-effectiveness-of-systemic-corticosteroids-in-children-with-croup
#11
Elizabeth Muñoz-Osores, Deidyland Arenas
Systemic corticosteroids constitute standard treatment in children with acute obstructive laryngitis (croup). However, there is some uncertainty in relation with the magnitude of the benefits and risks associated with their use. To answer this question, we used Epistemonikos, the largest database of systematic reviews in health, which is maintained by screening multiple information sources, including MEDLINE, EMBASE, Cochrane, among others. We identified six systematic reviews including 25 randomized trials relevant for the question of interest...
June 6, 2017: Medwave
https://www.readbyqxmd.com/read/28594619/managing-acute-respiratory-tract-infections-in-children
#12
C Schuster Bruce, Clare Hoare, Atanu Mukherjee, Siba Prosad Paul
Respiratory tract infections (RTIs), including community-acquired pneumonia (CAP), bronchiolitis, viral-induced wheeze and croup, account for more primary care consultations than any other illness group and are the most likely reason for a parent or carer to contact a health professional. The majority of RTIs in fully immunised children are usually self-limiting. However, in a small percentage of children RTIs may become life threatening and it is crucial that all front-line health professionals are able to recognise and identify these children who are at risk of deterioration...
June 8, 2017: British Journal of Nursing: BJN
https://www.readbyqxmd.com/read/28556543/westley-score-and-clinical-factors-in-predicting-the-outcome-of-croup-in-the-pediatric-emergency-department
#13
Wen-Chieh Yang, Jung Lee, Chun-Yu Chen, Yu-Jun Chang, Han-Ping Wu
BACKGROUND: Westley croup score has been generally used to assess the severity of croup. This study aimed to identify the individual factors associated with Westley score (WS) and other clinical factors in predicting the outcomes in the pediatric emergency department (PED). POPULATION AND METHOD: We prospectively recruited patients with croup from the PED. The individual factors of WS, fever, age, and the length of hospital stay were analyzed to predict clinical outcomes...
May 29, 2017: Pediatric Pulmonology
https://www.readbyqxmd.com/read/28537762/creation-of-an-integrated-knowledge-translation-process-to-improve-pediatric-emergency-care-in-canada
#14
Robin M Featherstone, Carly Leggett, Lisa Knisley, Mona Jabbour, Terry P Klassen, Shannon D Scott, Greg Van De Mosselaer, Lisa Hartling
TREKK (Translating Emergency Knowledge for Kids) was established to address knowledge needs to support care of children in general emergency departments. To achieve this goal, we developed an integrated knowledge translation (KT) process based on identified priorities to create the TREKK Evidence Repository, containing "knowledge pyramids" and Bottom Line Recommendations (summary documents) on the diagnosis and treatment of emergency pediatric conditions. The objective of this article is to describe our methods for developing and disseminating the TREKK Evidence Repository to improve pediatric emergency care in Canada...
May 24, 2017: Health Communication
https://www.readbyqxmd.com/read/28436091/effects-of-pre-education-combined-with-a-simulation-for-caring-for-children-with-croup-on-senior-nursing-students
#15
Myung-Nam Lee, Kyung-Ah Kang, Sun-Jung Park, Shin-Jeong Kim
Educational outcomes, such as knowledge, confidence in performance, ability in nursing practice, and satisfaction with learning methods in caring for children with croup, were compared between groups of students that received education through simulation combined with pre-education, simulation only, and pre-education only. In this quasi-experimental design, the educational intervention for the experimental group was the pre-education modality. Data from a convenience sample of 127 senior nursing students were drawn from three nursing schools in South Korea...
June 2017: Nursing & Health Sciences
https://www.readbyqxmd.com/read/28424887/a-metagenomics-study-for-the-identification-of-respiratory-viruses-in-mixed-clinical-specimens-an-application-of-the-iterative-mapping-approach
#16
Yu-Nong Gong, Shu-Li Yang, Guang-Wu Chen, Yu-Wen Chen, Yhu-Chering Huang, Hsiao-Chen Ning, Kuo-Chien Tsao
Metagenomic approaches to detect viral genomes and variants in clinical samples have various challenges, including low viral titers and bacterial and human genome contamination. To address these limitations, we examined a next-generation sequencing (NGS) and iterative mapping approach for virus detection in clinical samples. We analyzed 40 clinical specimens from hospitalized children diagnosed with acute bronchiolitis, croup, or respiratory tract infections in which virus identification by viral culture or polymerase chain reaction (PCR) was unsuccessful...
July 2017: Archives of Virology
https://www.readbyqxmd.com/read/28398936/endogenous-glucocorticoid-response-to-single-dose-dexamethasone-for-croup-in-children-a-pharmacodynamic-study
#17
Natasha Gill, Natalie Sirizzotti, David Johnson, Gary Joubert, Andrew S Kucey, Alvin Tieu, Brad L Urquhart, Melanie Columbus, Rodrick Lim, Michael Rieder, Shruti Mehrotra, Emily D Hartjes, Naveen Poonai
OBJECTIVES: Dexamethasone is associated with adrenal insufficiency in adults and children with chronic disease. This association has not been studied after single-dose oral dexamethasone, the standard of care for children with croup. We hypothesized that single-dose oral dexamethasone in children with croup is associated with a transient decrease in endogenous glucocorticoids. METHODS: We conducted a prospective, 2-arm, pharmacodynamic study of single-dose oral dexamethasone 0...
April 11, 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/28355170/comparing-practice-patterns-between-pediatric-and-general-emergency-medicine-physicians-a-scoping-review
#18
REVIEW
Nnenna O Chime, Jessica Katznelson, Sandeep Gangadharan, Barbara Walsh, Katie Lobner, Linda Brown, Marcie Gawel, Marc Auerbach
OBJECTIVE: Acutely ill infants and children presenting to the emergency department are treated by either physicians with pediatric emergency medicine (PEM) training or physicians without PEM training, a good proportion of which are general emergency medicine-trained physicians (GEDPs). This scoping review identified published literature comparing the care provided to infants and children (≤21 years of age) by PEM-trained physicians to that provided by GEDPs. METHODS: The search was conducted in 2 main steps as follows: (1) initial literature search to identify available literature with evolving feedback from the group while simultaneously deciding search concepts as well as inclusion and exclusion criteria and (2) modification of search concepts and conduction of search using finalized concepts as well as review and selection of articles for final analysis using set inclusion criteria...
April 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/28335827/management-of-acute-respiratory-diseases-in-the-pediatric-population-the-role-of-oral-corticosteroids
#19
REVIEW
Renato Cutrera, Eugenio Baraldi, Luciana Indinnimeo, Michele Miraglia Del Giudice, Giorgio Piacentini, Francesco Scaglione, Nicola Ullmann, Laura Moschino, Francesca Galdo, Marzia Duse
Respiratory diseases account for about 25% of all pediatric consultations, and 10% of these are for asthma. The other main pediatric respiratory diseases, in terms of incidence, are bronchiolitis, acute bronchitis and respiratory infections. Oral corticosteroids, in particular prednisolone, are often used to treat acute respiratory diseases given their anti-inflammatory effects. However, the efficacy of treatment with oral corticosteroids differs among the various types of pediatric respiratory diseases. Notably, also the adverse effects of corticosteroid treatment can differ depending on dosage, duration of treatment and type of corticosteroid administered - a case in point being growth retardation in long-course treatment...
March 23, 2017: Italian Journal of Pediatrics
https://www.readbyqxmd.com/read/28292873/variation-in-inpatient-croup-management-and-outcomes
#20
Amy Tyler, Lisa McLeod, Brenda Beaty, Elizabeth Juarez-Colunga, Meghan Birkholz, Daniel Hyman, Allison Kempe, James Todd, Amanda F Dempsey
BACKGROUND AND OBJECTIVES: Croup is a clinical diagnosis, and the available evidence suggests that, except in rare cases, ancillary testing, such as radiologic imaging, is not helpful. Given the paucity of inpatient-specific evidence for croup care, we hypothesized that there would be marked variability in the use of not routinely indicated resources (NRIRs). Our primary study objective was to describe the variation and predictors of variation in the use of NRIRs. METHODS: This was a retrospective cohort study that used the Pediatric Health Information System database of generally healthy inpatients with croup aged 6 months to 15 years who were admitted between January 1, 2012 and September 30, 2014...
April 2017: Pediatrics
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