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Xiao-Min Song, Hong Jiang, Wen-Xiang Zhang, Yun Zhou, Feng Ni, Xue-Mei Wang
AIM: The aim of this study was to compare the clinical outcomes of in vitro fertilization (IVF) for patients with hydrosalpinx between ultrasound sclerotherapy and surgical intervention. METHODS: The data of 482 IVF/intracytoplasmic sperm injection (ICSI) cycles were divided into three groups according to different intervention protocols before IVF/ICSI. Group A included 265 cycles in which ultrasound sclerotherapy pretreatment was carried out before controlled ovarian hyperstimulation...
October 20, 2016: Journal of Obstetrics and Gynaecology Research
Jared C Hiebert, Yan Daniel Zhao, Elena B Willis
IMPORTANCE: The etiology of recurrent croup is often anatomic. Currently there is no set criteria for determining who should undergo diagnostic bronchoscopy and which patients are at most risk for having a clinically significant finding. Few studies have addressed these questions. OBJECTIVE: To identify risk factors for clinically significant findings on bronchoscopy in children with recurrent croup and the frequency of bronchoscopy findings in general. DATA SOURCES: PUBMED, Ovid MEDLINE, EMBASE...
November 2016: International Journal of Pediatric Otorhinolaryngology
David Wyatt Johnson
No abstract text is available yet for this article.
September 15, 2016: American Family Physician
Vladimir Trukhachev, Valentin Skripkin, Andrey Kvochko, Alexander Kulichenko, Dmitry Kovalev, Sergey Pisarenko, Anna Volynkina, Marina Selionova, Magomet Aybazov, Natalia Golovanova, Olesya Yatsyk, Alexander Krivoruchko
An understanding of what effects particular genes can have on body parameters in productive animals is particularly significant for the process of marker-assisted selection. The gene of transcriptional factor CCAAT/enhancer-binding protein delta (CEBPD gene) is involved in the process of growth in animals and is known to be a promising candidate for use as a genomic marker. The structure of the CEBPD gene locus was determined using NimbleGen sequencing technology (Roche, USA). The effect of polymorphisms, which were identified using the aforementioned technology, was investigated in 30 rams of the Manych Merino sheep breed...
October 2016: Animal Biotechnology
Fahad Aljebab, Mofadhi Alanazi, Imti Choonara, Sharon Conroy
BACKGROUND: Corticosteroids are used to treat a variety of medical conditions including acute asthma and croup where they are often given in short-courses. Epidemiological studies in Saudi Arabia show an increasing prevalence of respiratory diseases such as asthma in the past three decades.1 This study aimed to evaluate the tolerability and palatability of oral prednisolone and dexamethasone in children in Saudi Arabia. Both drugs are available in different formulations from different pharmaceutical companies...
September 2016: Archives of Disease in Childhood
Sumana Fathima, Kimberley Simmonds, Jesse Invik, Allison N Scott, Steven Drews
BACKGROUND: Human Parainfluenza Virus (hPIV) causes severe respiratory illness in infants and adults. Our study describes the association of hPIV1-4 with bronchiolitis, croup, and pneumonia using retrospective laboratory, administrative and public health data. Due to issues including the historic lack of hPIV4 in some commercial respiratory virus panels, the description of the impact of hPIV4 on croup, bronchiolitis, and pneumonia at population levels has often been limited. This study will use routine clinical laboratory data, and administrative data to provide a preliminary description of the impact of hPIV4 on these diseases in our population...
2016: BMC Infectious Diseases
Ольга І Гладченко, Павло В Токарєв, Олександр Б Надрага
INTRODUCTION: One of the most severe complications of acute respiratory infections in young children is acute stenotic laryngotracheitis (croup). The relationship between cytokine blood levels and symptoms of croup, croup severity, disease sequel, despite numerous studies is still unclear. AIM: Cytokine profile in young children with acute stenotic laryngotracheitis investigation. MATERIAL AND METHODS: 112 children aged 12 min. - 36 mon. with acute stenotic laryngotracheitis which were treated at the Lviv Regional Infectious Diseases Hospital were kept under observation...
2016: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
Angela R Branche, Ann R Falsey
Human parainfluenza viruses (HPIVs) are single-stranded, enveloped RNA viruses of the Paramyoviridaie family. There are four serotypes which cause respiratory illnesses in children and adults. HPIVs bind and replicate in the ciliated epithelial cells of the upper and lower respiratory tract and the extent of the infection correlates with the location involved. Seasonal HPIV epidemics result in a significant burden of disease in children and account for 40% of pediatric hospitalizations for lower respiratory tract illnesses (LRTIs) and 75% of croup cases...
August 2016: Seminars in Respiratory and Critical Care Medicine
Michael Åkesson, Leena Lehti, Peter Höglund, Per Åkeson, Johan Wassélius
BACKGROUND: High-quality non-invasive imaging of the deep venous system in the thorax is challenging, but nevertheless required for diagnosis of vascular pathology as well as for patient selection and preoperative planning for endovascular procedures. PURPOSE: To compare the diagnostic quality of Gadofosveset-enhanced thoracic magnetic resonance venography, seven consecutive patients with suspected or known disease affecting the central thoracic veins were compared to seven consecutive magnetic resonance venography using conventional gadolinium-based contrast agents...
July 6, 2016: Phlebology
Vanessa E Murphy, Megan E Jensen, Joerg Mattes, Michael J Hensley, Warwick B Giles, Michael J Peek, Andrew Bisits, Leonie K Callaway, Kirsten McCaffery, Helen L Barrett, Paul B Colditz, Sean K Seeho, John Attia, Andrew Searles, Christopher Doran, Heather Powell, Peter G Gibson
BACKGROUND: Asthma exacerbations are common during pregnancy and associated with an increased risk of adverse perinatal outcomes. Adjusting asthma treatment based on airway inflammation rather than symptoms reduces the exacerbation rate by 50 %. The Breathing for Life Trial (BLT) will test whether this approach also improves perinatal outcomes. METHODS/DESIGN: BLT is a multicentre, parallel group, randomised controlled trial of asthma management guided by fractional exhaled nitric oxide (FENO, a marker of eosinophilic airway inflammation) compared to usual care, with prospective infant follow-up...
2016: BMC Pregnancy and Childbirth
Candice L Bjornson, Janielee Williamson, David W Johnson
OBJECTIVE: The objective was to derive a simple clinical scoring instrument for assessing children with croup by telephone for use in clinical research studies. METHODS: We reviewed published literature on croup scores, surveyed experienced pediatric emergency nurses and physicians, and conducted a prospective cohort study. Score items were derived from published literature and surveys of experienced clinicians. We enrolled children with croup attending an urban pediatric emergency department...
May 2016: Pediatric Emergency Care
Patrick D Munson
OBJECTIVES: To determine if children with recurrent croup (RC) and persistent laryngomalacia (LM) clinically improve after supraglottoplasty (SGP). MATERIAL AND METHODS: Retrospective chart review cohort at tertiary care children's hospital consisting of patients diagnosed with LM and RC that underwent SGP from July 2011 to August 2014. Clinical history, demographics, clinical outcomes, and operative complications were reviewed. Specifically, the episodes of croup requiring systemic steroids were compared pre- and post-SGP with statistical analysis...
May 2016: International Journal of Pediatric Otorhinolaryngology
C C Grant, J Crane, E A Mitchell, J Sinclair, A Stewart, T Milne, J Knight, C Gilchrist, C A Camargo
BACKGROUND: Vitamin D has immune-modulating effects. We determined whether vitamin D supplementation during pregnancy and infancy prevents aeroallergen sensitization and primary care respiratory illness presentations. METHODS: A randomized, double-blind, placebo-controlled parallel-group trial. We assigned pregnant women, from 27-week gestation to birth, and then their infants, from birth to 6 months, to placebo or one of two dosages of daily oral vitamin D. Woman/infant pairs were randomized to: placebo/placebo, 1000 IU/400 IU or 2000 IU/800 IU...
September 2016: Allergy
Osman Yeşilbaş, Hasan Serdar Kıhtır, Mey Talip Petmezci, Seda Balkaya, Nevin Hatipoğlu, Sevim Meşe, Esra Şevketoğlu
Human bocavirus (HBoV), that was first identified in 2005 and classified in Parvoviridae family, is a small, non-enveloped, single-stranded DNA virus, responsible for upper and lower respiratory tract infections, especially in young children. Although HBoV generally causes self-limited influenza-like illness, it may also lead to pneumonia, bronchiolitis, croup and asthma attacks. In this report, a case of acute bronchiolitis complicated with pneumomediastinum and bilateral pneumothorax caused by HBoV has been presented...
January 2016: Mikrobiyoloji Bülteni
B Gelbart, S Parsons, A Sarpal, P Ninova, W Butt
Croup remains the commonest reason for acute upper airway obstruction in children, yet there are scarce contemporary data of airway management in those requiring intubation. We performed a retrospective analysis of the intensive care management of children intubated for croup in two quaternary Paediatric Intensive Care Units: Royal Children's Hospital Melbourne, Australia and Alberta Children's Hospital Calgary, Canada. Patients intubated for less than three days were compared with those intubated for greater than three days...
March 2016: Anaesthesia and Intensive Care
Laura M Palermo, Manik Uppal, Lucy Skrabanek, Paul Zumbo, Soren Germer, Nora C Toussaint, Bert K Rima, Devra Huey, Stefan Niewiesk, Matteo Porotto, Anne Moscona
UNLABELLED: Respiratory paramyxoviruses, including the highly prevalent human parainfluenza viruses, cause the majority of childhood croup, bronchiolitis, and pneumonia, yet there are currently no vaccines or effective treatments. Paramyxovirus research has relied on the study of laboratory-adapted strains of virus in immortalized cultured cell lines. We show that findings made in such systems about the receptor interaction and viral fusion requirements for entry and fitness-mediated by the receptor binding protein and the fusion protein-can be drastically different from the requirements for infection in vivo...
2016: MBio
Elif C Cingi, David S Beebe, Chester B Whitley, Kumar G Belani
BACKGROUND: Patients with mucopolysaccharidoses (MPS) are generally considered high risk for anesthesia care, owing to disease-related factors. Sanfilippo syndrome type A (MPS IIIA) is the most frequently occurring MPS. Anesthesia-specific information for MPS IIIA is not readily available in the literature. OBJECTIVES: To report post hoc analyses on anesthesia care and outcomes from a 2-year study of the natural history of patients with untreated MPS IIIA (NCT01047306)...
May 2016: Paediatric Anaesthesia
Fenghua Wang, Cheng Chen, Wenjie Tan, Kailin Yang, Haitao Yang
First identified in The Netherlands in 2004, human coronavirus NL63 (HCoV-NL63) was found to cause worldwide infections. Patients infected by HCoV-NL63 are typically young children with upper and lower respiratory tract infection, presenting with symptoms including croup, bronchiolitis, and pneumonia. Unfortunately, there are currently no effective antiviral therapy to contain HCoV-NL63 infection. CoV genomes encode an integral viral component, main protease (M(pro)), which is essential for viral replication through proteolytic processing of RNA replicase machinery...
2016: Scientific Reports
Kitty Leung, Christopher J L Newth, Justin C Hotz, Kevin C O'Brien, James B Fink, Allan L Coates
OBJECTIVES: The Vapotherm system delivers high humidity to the airway of patients by using semipermeable tubules where heated liquid water is in contact with air. The humidified air is conducted to the patient via a heated tube. Preliminary clinical observations in infants with croup suggested that epinephrine added to the water supplying the humidity was delivered successfully in the vapor phase. The purpose of this study was to evaluate the efficiency of the delivery of epinephrine in the vapor phase and to develop the feasibility criteria for a clinical pilot study...
April 2016: Pediatric Critical Care Medicine
Nawal Al-Maskari, Jalila Mohsin, Amal Al-Maani, Nabil Al-Macki, Suad Al-Ismaili
The respiratory syncytial virus (RSV) usually causes a lower respiratory tract infection in affected patients. RSV has also been infrequently linked to extrapulmonary diseases in children. We report four children who had unusually severe clinical manifestations of RSV infections requiring critical care admission. These patients presented to the Royal Hospital, Muscat, Oman, in December 2013 with acute necrotising encephalopathy (ANE), acute fulminant hepatic failure with encephalopathy, pneumatoceles and croup...
February 2016: Sultan Qaboos University Medical Journal
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