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Intergenerational transmission

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https://www.readbyqxmd.com/read/27929335/intergenerational-transmission-of-socioeconomic-position-and-ideal-cardiovascular-health-32-year-follow-up-study
#1
Kateryna Savelieva, Laura Pulkki-Råback, Markus Jokela, Laura Diane Kubzansky, Marko Elovainio, Vera Mikkilä, Tuija Tammelin, Markus Juonala, Olli T Raitakari, Liisa Keltikangas-Järvinen
OBJECTIVES: Socioeconomic position (SEP) in childhood predicts cardiovascular health in adulthood but the underlying mechanisms remain unclear. Using a longitudinal study design, we examined the extent to which adult SEP acts as a pathway (mediator) connecting childhood SEP with adult cardiovascular health, and if upward social mobility mitigates the health-effects of early low SEP. METHOD: The sample comprised 697 participants from a prospective Finnish cohort followed during 32 years...
December 8, 2016: Health Psychology: Official Journal of the Division of Health Psychology, American Psychological Association
https://www.readbyqxmd.com/read/27929313/maternal-executive-functioning-as-a-mechanism-in-the-intergenerational-transmission-of-parenting-preliminary-evidence
#2
David J Bridgett, Meghan J Kanya, Helena J V Rutherford, Linda C Mayes
Multiple lines of inquiry, including experimental animal models, have recently converged to suggest that executive functioning (EF) may be one mechanism by which parenting behavior is transmitted across generations. In the current investigation, we empirically test this notion by examining relations between maternal EF and parenting behaviors during mother-infant interactions, and by examining the role of maternal EF in the intergenerational transmission of parenting behavior. Mother-infant dyads (N = 150) in a longitudinal study participated...
December 8, 2016: Journal of Family Psychology: JFP
https://www.readbyqxmd.com/read/27914238/intergenerational-transmission-of-child-abuse-and-neglect-do-maltreatment-type-perpetrator-and-substantiation-status-matter
#3
Jessica Dym Bartlett, Chie Kotake, Rebecca Fauth, M Ann Easterbrooks
A maternal history of childhood maltreatment is thought to be a potent risk factor for child abuse and neglect, yet the extent of continuity across generations is unclear, with studies reporting vastly different rates of intergenerational transmission. Disparate findings may be due to lack of attention to the nature of maltreatment experiences in each generation. We sought to expand the current literature by examining the role of maltreatment type, perpetrator identity, and substantiation status of reports to child protective services (CPS) on intergenerational maltreatment among adolescent mothers (n=417) and their children...
November 30, 2016: Child Abuse & Neglect
https://www.readbyqxmd.com/read/27913616/genetic-contributors-to-intergenerational-cag-repeat-instability-in-huntington-s-disease-knock-in-mice
#4
João Luís Neto, Jong-Min Lee, Ali Afridi, Tammy Gillis, Jolene R Guide, Stephani Dempsey, Brenda Lager, Isabel Alonso, Vanessa C Wheeler, Ricardo Mouro Pinto
Huntington's disease is a neurodegenerative disorder caused by the expansion of a CAG trinucleotide repeat in exon 1 of the HTT gene. Longer repeat sizes are associated with increased disease penetrance and earlier ages of onset. Intergenerationally unstable transmissions are common in Huntington's disease families, partly underlying the genetic anticipation seen in this disorder. Huntington's disease CAG knock-in mouse models also exhibit a propensity for intergenerational repeat size changes. In this work, we examine intergenerational instability of the CAG repeat in over 20,000 transmissions in the largest Huntington's disease knock-in mouse model breeding datasets reported to date...
December 2, 2016: Genetics
https://www.readbyqxmd.com/read/27909834/effects-of-maternal-health-anxiety-on-children-s-health-complaints-emotional-symptoms-and-quality-of-life
#5
Mette Viller Thorgaard, Lisbeth Frostholm, Lynn S Walker, Kristian Stengaard-Pedersen, Mads Münster Karlsson, Jens Søndergaard Jensen, Per Fink, Charlotte Ulrikka Rask
Little is known about family risk factors and intergenerational transmission of psychological disturbance in the development of health anxiety (HA). This study investigated HA and related concepts in 8- to 17-year-old children who had been exposed to different maternal health status. Using a family case-control design, three family groups were included: (1) 50 case children of mothers with severe (HA); (2) 49 control children of mothers with rheumatoid arthritis (RA); and (3) 51 control children of healthy mothers...
December 1, 2016: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/27899809/does-vaginal-delivery-mitigate-or-strengthen-the-intergenerational-association-of-overweight-and-obesity-findings-from-the-boston-birth-cohort
#6
N T Mueller, G Mao, W Bennet, S Hourigan, M G Dominguez-Bello, L J Appel, X Wang
BACKGROUND/OBJECTIVES: The intergenerational association of obesity may be driven by mother-to-newborn transmission of microbiota at birth. Yet Cesarean delivery circumvents newborn acquisition of vaginal microbiota, and has been associated with greater childhood adiposity. Here we examined the independent and joint associations of maternal pre-pregnancy BMI (kg/m(2)) and delivery mode with childhood overweight or obesity. SUBJECTS/METHODS: We prospectively followed 1441 racially and ethnically diverse mother-child dyads in the Boston Birth Cohort until age 5y (range 2...
November 30, 2016: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/27880620/a-relational-model-for-the-intergenerational-transmission-of-captivity-trauma-a-23-year-longitudinal-study
#7
Gadi Zerach, Zahava Solomon
OBJECTIVES: The aversive, long-term toll of war captivity and fathers' combat-induced posttraumatic stress disorder (PTSD) on adult offspring's secondary traumatization (ST) has been recently exemplified. However, the study of potential mechanisms of the intergenerational transmission of trauma to offspring is still lacking. This prospective study aimed to assess the role of fathers' PTSD symptoms (PTSS), paternal parenting, and adult offspring's attachment insecurities in adult offspring's PTSS...
2016: Psychiatry
https://www.readbyqxmd.com/read/27876818/identification-and-characterization-of-5-ccg-interruptions-in-complex-dmpk-expanded-alleles
#8
Annalisa Botta, Giulia Rossi, Marzia Marcaurelio, Luana Fontana, Maria Rosaria D'Apice, Francesco Brancati, Roberto Massa, Darren G Monckton, Federica Sangiuolo, Giuseppe Novelli
Myotonic dystrophy type 1 is a multisystemic autosomal dominant disorder caused by the expansion of (CTG) n triplets in the 3'UTR of the DMPK gene, on chromosome 19q13.3. In the last years, few DM1 patients with different patterns of CCG/CTC interruptions at the 3' end of the DMPK expanded tract have been described. However, the role of these interruptions in DM1 pathogenesis is still unclear. To study the frequency, stability and the structure of DMPK variant expanded alleles in the Italian population, we have re-evaluated 254 Italian DM1 patients using triplet-primed PCR (TP-PCR), at both the 3' and 5' ends of the CTG expansion...
November 23, 2016: European Journal of Human Genetics: EJHG
https://www.readbyqxmd.com/read/27874726/maternal-child-sexual-abuse-is-associated-with-lower-maternal-warmth-toward-daughters-but-not-sons
#9
Dorthie Cross, Ye Ji Kim, L Alexander Vance, Gabriella Robinson, Tanja Jovanovic, Bekh Bradley
Mothers with a history of child sexual abuse report less warmth toward their children, but whether this association differs by child gender is unknown. We examined the association of maternal child sexual abuse and warmth across child gender, accounting for depression, post-traumatic stress disorder, and child physical abuse. We verbally administered self-report measures to a cross-sectional sample of 154 mothers with a child between 8 and 12 years old. Eighty-five mothers based warmth responses on a son, and 69 on a daughter...
November 2016: Journal of Child Sexual Abuse
https://www.readbyqxmd.com/read/27873371/getting-a-sporting-chance-title-ix-and-the-intergenerational-transmission-of-health
#10
Lisa Schulkind
We know that healthier mothers tend to have healthier infants, but we do not know how much of that relationship reflects the intergenerational transmission of genetic attributes versus environmental influences. From a policy perspective, it is crucial to understand which environmental influences are important and whether investments in one generation affect outcomes for the next. I use variation in the implementation of Title IX to measure the effects of increased athletic opportunities on the health of infants...
November 22, 2016: Health Economics
https://www.readbyqxmd.com/read/27869483/the-epigenetic-impacts-of-social-stress-how-does-social-adversity-become-biologically-embedded
#11
Vincent T Cunliffe
Epigenetic mechanisms are implicated in the processes through which social stressors erode health in humans and other animals. Here I review progress in elucidating the biological pathways underlying the social gradient in health, with particular emphasis on how behavioral stresses influence epigenomic variation linked to health. The evidence that epigenetic changes are involved in embedding of social status-linked chronic stress is reviewed in the context of current knowledge about behavior within animal dominance hierarchies and the impacts of social position on behaviors that affect health...
November 21, 2016: Epigenomics
https://www.readbyqxmd.com/read/27866501/promoting-children-s-learning-and-development-in-conflict-affected-countries-testing-change-process-in-the-democratic-republic-of-the-congo
#12
J Lawrence Aber, Carly Tubbs, Catalina Torrente, Peter F Halpin, Brian Johnston, Leighann Starkey, Anjuli Shivshanker, Jeannie Annan, Edward Seidman, Sharon Wolf
Improving children's learning and development in conflict-affected countries is critically important for breaking the intergenerational transmission of violence and poverty. Yet there is currently a stunning lack of rigorous evidence as to whether and how programs to improve learning and development in conflict-affected countries actually work to bolster children's academic learning and socioemotional development. This study tests a theory of change derived from the fields of developmental psychopathology and social ecology about how a school-based universal socioemotional learning program, the International Rescue Committee's Learning to Read in a Healing Classroom (LRHC), impacts children's learning and development...
November 21, 2016: Development and Psychopathology
https://www.readbyqxmd.com/read/27859442/couple-forgiveness-and-its-moderating-role-in-the-intergenerational-transmission-of-veterans-posttraumatic-stress-symptoms
#13
Xiao Zhou, Yafit Levin, Jacob Y Stein, Gadi Zerach, Zahava Solomon
This study examined the moderating effect couple forgiveness (as perceived by the wives/mothers) may have on the intergenerational transmission of posttraumatic stress symptoms (PTSS) among families of combat veterans and former prisoners of war (ex-POWs). The sample included 123 (79 ex-POWs and 44 control combatants) Israeli father-mother-adult offspring triads. Self-report measures were administered at 2008 to veterans, at 2010-2011 to wives, and at 2013-2014 to offspring. The findings indicated that ex-POWs' PTSS were positively related to their offspring's PTSS, while couple forgiveness buffered this effect, particularly, and detrimentally, when couple forgiveness was low...
November 18, 2016: Journal of Marital and Family Therapy
https://www.readbyqxmd.com/read/27851798/intergenerational-transmission-of-overweight-and-obesity-from-parents-to-their-adolescent-offspring-the-hunt-study
#14
Marit Næss, Turid Lingaas Holmen, Mette Langaas, Johan Håkon Bjørngaard, Kirsti Kvaløy
PURPOSE: The main aim of this study was to examine weight associations between parents and offspring at two time points: 1995-97 and 2006-08, taking into account body mass index (BMI) and waist circumference. METHODS: The study included 8425 parent-offspring trios who participated in the population based Health Study of Nord Trøndelag (the HUNT Study), Norway, at either the HUNT2 (1995-97) or the HUNT3 (2006-08) survey. We used linear mixed effects models with siblings clustered within mothers to analyze the associations between 1) parental grouped BMI and offspring BMI z-scores and 2) parental grouped waist circumference and offspring waist circumference z-scores...
2016: PloS One
https://www.readbyqxmd.com/read/27843844/the-intergenerational-transmission-of-tobacco-habit-role-of-parents-and-the-family
#15
Shridhar Dwivedi, Rambha Pathak, Rashmi Agarwalla, Wazid Ali
INTRODUCTION: Tobacco pandemic has become one of the greatest public health challenges of all time. The socio-environmental factors prevailing at home have been identified as one of the most important causes of adopting smoking and other types of smokeless tobacco. OBJECTIVES: The present study was conducted to find out the prevalence and pattern of tobacco use in the patients registered in the clinic and to study the role of parental and family influence on tobacco use...
April 2016: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/27836569/child-height-and-intergenerational-transmission-of-health-evidence-from-ethnic-indians-in-england
#16
Caterina Alacevich, Alessandro Tarozzi
A large literature documents a widespread prevalence of small stature among Indian children as well as adults. We show that a height gap relative to a richer population such as whites in England also exists, although substantially reduced, among adult immigrants of Indian ethnicity in England. This is despite positive height selection into migration, demonstrated by ethnic Indian adults in England being on average 6-7cm taller than in India. However, the difference between natives and ethnic Indians in England disappears among their younger sons and daughters, although it re-appears among adolescents...
October 24, 2016: Economics and Human Biology
https://www.readbyqxmd.com/read/27818520/if-intergenerational-transmission-is-the-problem-then-what-is-the-solution
#17
Marek S Kopacz, Craig J Bryan
No abstract text is available yet for this article.
December 2016: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/27814961/experiential-avoidance-in-the-vulnerability-to-depression-among-adolescent-females
#18
William Mellick, Salome Vanwoerden, Carla Sharp
BACKGROUND: Although various mechanisms in the maternal transmission of Major Depressive Disorder (MDD) have been investigated, it is unknown whether experiential avoidance (EA) is a vulnerability factor in the development of depression or a consequence of the illness. The present study utilized a high-risk design to determine if EA indeed poses vulnerability to adolescent MDD. Secondly, we examined the means by which adolescent EA may come to pose vulnerability, namely that it explains the relation between maternal EA and adolescent depressive symptoms...
October 27, 2016: Journal of Affective Disorders
https://www.readbyqxmd.com/read/27793275/violent-experiences-in-childhood-are-associated-with-men-s-perpetration-of-intimate-partner-violence-as-a-young-adult-a-multistage-cluster-survey-in-malawi
#19
Kristin VanderEnde, James Mercy, Mary Shawa, McKnight Kalanda, Justin Hamela, Nankali Maksud, Brendan Ross, Sundeep Gupta, Nellie Wadonda-Kabondo, Susan Hillis
PURPOSE: To examine the association between exposures to violence in childhood, including exposure to multiple forms of violence, with young men's perpetration of intimate partner violence (IPV) in Malawi. METHODS: We analyzed data from 450 ever-partnered 18- to 24-year-old men interviewed in the Malawi Violence Against Children and Young Woman Survey, a nationally representative, multistage cluster survey conducted in 2013. We estimated the weighted prevalence for perpetration of physical and/or sexual IPV and retrospective reporting of experiences of violence in childhood and examined the associations between childhood experiences of violence and perpetration of IPV using logistic regression...
October 2016: Annals of Epidemiology
https://www.readbyqxmd.com/read/27791108/extracellular-rna-is-transported-from-one-generation-to-the-next-in-caenorhabditis-elegans
#20
Julia Marré, Edward C Traver, Antony M Jose
Experiences during the lifetime of an animal have been proposed to have consequences for subsequent generations. Although it is unclear how such intergenerational transfer of information occurs, RNAs found extracellularly in animals are candidate molecules that can transfer gene-specific regulatory information from one generation to the next because they can enter cells and regulate gene expression. In support of this idea, when double-stranded RNA (dsRNA) is introduced into some animals, the dsRNA can silence genes of matching sequence and the silencing can persist in progeny...
November 1, 2016: Proceedings of the National Academy of Sciences of the United States of America
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