keyword
https://read.qxmd.com/read/38536198/fulbright-as-opportunity-for-u-s-nursing-educators-and-international-nursing-schools
#1
JOURNAL ARTICLE
Lynda Boyer-Chu, Thu H T Huynh, Ngoan T N Nguyen, Tuyen K T Bui, Giang H L Ngo, Dao T Vu, Hieu H T Lam, Uyen B T Truong
BACKGROUND: Nursing education across the globe is rapidly evolving in terms of curricular expectations and professional preparation. While there is a plethora of curricular resources and graduate programs in the United States, in some countries, these resources are limited. METHODS: The Fulbright Specialist program, the application process, and challenges as well as the benefits of the role are described. The deliverables by the Fulbright Specialist, e.g. demonstrating classroom pedagogical methods, providing access to an online doctoral program, and explaining publication strategies, are noted...
March 25, 2024: Journal of Nursing Education
https://read.qxmd.com/read/38532666/seroprevalence-of-sars-cov-2-in-10-regional-capitals-of-cameroon-october-december-2020
#2
JOURNAL ARTICLE
Karampreet Sachathep, Yen T Duong, Giles Reid, Emily Kainne Dokubo, Judith D Shang, Clement B Ndongmo, Ekali Gabriel, G Tharp, Laura Eno Dimite, Adama N'Dir, Gordon Okpu, Francis M Ogollah, Dubliss Nguafack, Martin C Ntse, Gili Hrusa, Katherine Yuengling, Megan Tebbenhoff, Essomba René, Ngo Sack Françoise, Naah Tabala Felicity, Marie Claire Okomo, Anne-Cecile Zoung-Kanyi Bissek, Tiffany G Harris
BACKGROUND: Cameroon was among the most affected African countries during the first wave of the COVID-19 pandemic; however, the true prevalence of SARS-CoV-2 remains unknown. METHODS: From October to December 2020, we conducted a cross-sectional, age-stratified SARS-CoV-2 seroepidemiological survey at 30 purposively selected community-based sites across Cameroon's 10 regional capitals, sampling 10,000 individuals aged 5 years or older. We employed a parallel SARS-CoV-2 antibody testing algorithm (WANTAI ELISA and Abbott Architect) to improve both the positive predictive value and negative predictive value of seroprevalence...
April 2024: Influenza and Other Respiratory Viruses
https://read.qxmd.com/read/38532308/optimizing-triage-practice-in-pediatric-trauma-lessons-from-under-triage-and-over-triage-rates-and-risk-factors
#3
JOURNAL ARTICLE
Lisa C Ngo, Hayley M Carroll, Stephanie Salgueiro Massimilian, Nikitha Garapaty, Kelsey Palladino, Shenae K Samuels, Oliver B Lao, Joshua P Parreco, Tamar Levene
BACKGROUND: Triage accuracy is essential for delivering effective trauma care, especially in the pediatric population where unique challenges exist. The purpose of this study was to investigate risk factors contributing to under-triage and over-triage in an urban pediatric trauma center. METHODS: This retrospective cohort study included all trauma activations at an urban level 1 trauma center between January 1, 2021, and July 31, 2023 (patients <18 years old...
March 26, 2024: American Surgeon
https://read.qxmd.com/read/38531936/transformer-fault-diagnosis-method-based-on-smote-and-ngo-gbdt
#4
JOURNAL ARTICLE
Li-Zhong Wang, Jian-Fei Chi, Ye-Qiang Ding, Hai-Yan Yao, Qiang Guo, Hai-Qi Yang
In order to improve the accuracy of transformer fault diagnosis and improve the influence of unbalanced samples on the low accuracy of model identification caused by insufficient model training, this paper proposes a transformer fault diagnosis method based on SMOTE and NGO-GBDT. Firstly, the Synthetic Minority Over-sampling Technique (SMOTE) was used to expand the minority samples. Secondly, the non-coding ratio method was used to construct multi-dimensional feature parameters, and the Light Gradient Boosting Machine (LightGBM) feature optimization strategy was introduced to screen the optimal feature subset...
March 26, 2024: Scientific Reports
https://read.qxmd.com/read/38531874/profiling-the-colonic-mucosal-response-to-fecal-microbiota-transplantation-identifies-a-role-for-gbp5-in-colitis-in-humans-and-mice
#5
JOURNAL ARTICLE
Laurence D W Luu, Abhimanu Pandey, Sudarshan Paramsothy, Chinh Ngo, Natalia Castaño-Rodríguez, Cheng Liu, Michael A Kamm, Thomas J Borody, Si Ming Man, Nadeem O Kaakoush
Host molecular responses to fecal microbiota transplantation (FMT) in ulcerative colitis are not well understood. Here, we profile the human colonic mucosal transcriptome prior to and following FMT or placebo to identify molecules regulated during disease remission. FMT alters the transcriptome above the effect of placebo (n = 75 vs 3 genes, q < 0.05), including modulation of structural, metabolic and inflammatory pathways. This response is attributed to responders with no consistency observed in non-responders...
March 26, 2024: Nature Communications
https://read.qxmd.com/read/38527945/a-comparative-assessment-of-reference-genes-in-mouse-brown-adipocyte-differentiation-and-thermogenesis-in-vitro
#6
JOURNAL ARTICLE
Trang Huyen Lai, Jin Seok Hwang, Quang Nhat Ngo, Dong-Kun Lee, Hyun Joon Kim, Deok Ryong Kim
Adipogenic differentiation and thermogenesis in brown adipose tissue (BAT) undergo dynamic processes, altering phenotypes and gene expressions. Proper reference genes in gene expression analysis are crucial to mitigate experimental variances and ensure PCR efficacy. Unreliable reference genes can lead to erroneous gene expression quantification, resulting in data misinterpretation. This study focused on identifying suitable reference genes for mouse brown adipocyte research, utilizing brown adipocytes from the Ucp1-luciferase ThermoMouse model...
December 2024: Adipocyte
https://read.qxmd.com/read/38523706/rifampicin-resistant-mycobacterium-tuberculosis-in-vietnam-2020-2022
#7
JOURNAL ARTICLE
Hung Van Nguyen, Hoa Binh Nguyen, Doan Thu Ha, Dinh Thi Huong, Vu Ngoc Trung, Khieu Thi Thuy Ngoc, Tran Huyen Trang, Ha Vu Thi Ngoc, Tram Trinh Thi Bich, Trieu Le Pham Tien, Hanh Nguyen Hong, Phu Phan Trieu, Luong Kim Lan, Kim Lan, Ngo Ngoc Hue, Nguyen Thi Le Huong, Tran Le Thi Ngoc Thao, Nguyen Le Quang, Thu Do Dang Anh, Nguyễn Hữu Lân, Truong Van Vinh, Dang Thi Minh Ha, Phan Thuong Dat, Nguyen Phuc Hai, Derrick W Crook, Nguyen Thuy Thuong Thuong, Nhung Viet Nguyen, Guy E Thwaites, Timothy M Walker
OBJECTIVE: We conducted a descriptive analysis of multi-drug resistant tuberculosis (MDR-TB) in Vietnam's two largest cities, Hanoi and Ho Chi Minh city. METHODS: All patients with rifampicin resistant tuberculosis were recruited from Hanoi and surrounding provinces between 2020 and 2022. Additional patients were recruited from Ho Chi Minh city over the same time period. Demographic data were recorded from all patients, and samples collected, cultured, whole genome sequenced and analysed for drug resistance mutations...
May 2024: Journal of Clinical Tuberculosis and Other Mycobacterial Diseases
https://read.qxmd.com/read/38522974/the-development-and-implementation-of-the-fast-pace-assessment-framework-and-tiered-analgesic-orders-for-opioid-optimization
#8
JOURNAL ARTICLE
Marilyn Bazinski, Catherine Lau, Brooke Clemons, Lisa Purser, Amy Kangwankij, Lena Ngo, Michael Lang, Brianna Besen, Kendall Gross, Amber Borucki, Matthias Behrends, Christine Miaskowski, Hildy Schell-Chaple
BACKGROUND: Within the context of the opioid epidemic, changes needed to be made in the prescription and administration of analgesics. The purpose of this paper is to describe the development and implementation of a project that utilized a holistic pain assessment framework and introduced new order sets to guide the integration of nonopioid, opioid, and co-analgesics in a quaternary care medical center. METHODS: An interdisciplinary team updated policies and procedures for pain assessment and opioid administration and created new analgesic order sets for both adult and pediatric patients...
March 23, 2024: Pain Management Nursing: Official Journal of the American Society of Pain Management Nurses
https://read.qxmd.com/read/38521109/tailoring-hierarchical-structures-in-cellulose-carbon-aerogels-from-sugarcane-bagasse-using-different-crosslinking-agents-for-enhancing-electrochemical-desalination-capability
#9
JOURNAL ARTICLE
Thanh Tung Nguyen, Ngan Tuan Nguyen, Hoang Long Ngo, Van Vien Nguyen, Anh Hong Nguyen, Bao Dung Hoang Tran, Trung Kien Vo, Duy Tan Truong, Le Thanh Nguyen Huynh, Thanh Nhut Tran, Viet Hai Le, Thai Hoang Nguyen, Tan Le Hoang Doan
Sugarcane bagasse is one of the most common Vietnamese agricultural waste, which possesses a large percentage of cellulose, making it an abundant and environmentally friendly source for the fabrication of cellulose carbon aerogel. Herein, waste sugarcane bagasse was used to synthesize cellulose aerogel using different crosslinking agents such as urea, polyvinyl alcohol (PVA) and sodium alginate (SA). The 3D porous network of cellulose aerogels was constructed by intermolecular hydrogen bonding, which was confirmed by Fourier transform infrared (FTIR), X-ray diffraction (XRD), scanning electron microscopy (SEM) and nitrogen adsorption/desorption...
March 21, 2024: Chemosphere
https://read.qxmd.com/read/38520821/spatial-omics-techniques-and-data-analysis-for-cancer-immunotherapy-applications
#10
REVIEW
Yue Zhang, Ren Yuan Lee, Chin Wee Tan, Xue Guo, Willa W-Y Yim, Jeffrey Ct Lim, Felicia Yt Wee, W U Yang, Malvika Kharbanda, Jia-Ying J Lee, Nye Thane Ngo, Wei Qiang Leow, Lit-Hsin Loo, Tony Kh Lim, Radoslaw M Sobota, Mai Chan Lau, Melissa J Davis, Joe Yeong
In-depth profiling of cancer cells/tissues is expanding our understanding of the genomic, epigenomic, transcriptomic, and proteomic landscape of cancer. However, the complexity of the cancer microenvironment, particularly its immune regulation, has made it difficult to exploit the potential of cancer immunotherapy. High-throughput spatial omics technologies and analysis pipelines have emerged as powerful tools for tackling this challenge. As a result, a potential revolution in cancer diagnosis, prognosis, and treatment is on the horizon...
March 22, 2024: Current Opinion in Biotechnology
https://read.qxmd.com/read/38519934/perioperative-outcomes-of-the-surgical-management-of-achalasia-in-two-tertiary-cameroonian-hospitals-a-cohort-study
#11
JOURNAL ARTICLE
Joël Igor Kamla, Guy Aristide Bang, Joel Noutakdie Tochie, George Motto Bwelle, Blondel Nana Oumarou, Bernadette Ngo Nonga
INTRODUCTION: Achalasia is a rare esophageal disease with potentially lethal complications. Knowledge of the outcomes of the different surgical treatment modalities for achalasia by Heller's cardiomyotomy (HCM) helps to choose the safest and most effective option. However, data on the management of achalsia using a Heller myotomy is limited in Africa. Thus, our aim was to determine the perioperative morbidity, mortality and short-term functional outcomes of HCM in Cameroon. METHODOLOGY: We conducted a cohort study throughout a 10-year chart review of patients who underwent HCM for achalasia and were followed up postoperatively for at least three months at two tertiary health centers in Cameroon...
March 22, 2024: BMC Gastroenterology
https://read.qxmd.com/read/38519750/exploring-the-phytochemical-diversity-and-antioxidant-potential-of-the-vietnamese-smilax-glabra-roxb-insights-from-uplc-qtof-ms-ms-and-zebrafish-model-studies
#12
JOURNAL ARTICLE
Vu Thanh Nguyen, Vo Thi Minh Thao, Le Luu Phuong Hanh, Thi Hoa Rol, Ngo Huynh Phuong Thao, Tong Xuan Nguyen, Pham Thanh Luu, Dinh Thi Thuy
Research on natural products is growing due to their potential health benefits and medicinal properties. Despite regional variations in phytochemical composition and bioactivity, Smilax glabra Roxb (SGB) has attracted the interest of researchers. Scientists are particularly interested in the Vietnamese SGB variant, which is influenced by biological and environmental factors. Despite geographical differences in phytochemical makeup and bioactivities, SGB remains a fascinating subject in traditional herbal medicine...
March 23, 2024: Applied Biochemistry and Biotechnology
https://read.qxmd.com/read/38518977/non-sclerosing-t-cell-and-sclerosing-b-cell-lymphocytic-lobulitis-in-diagnostic-breast-biopsies-clinical-imaging-and-pathologic-features
#13
JOURNAL ARTICLE
Marie-Helene Ngo, Geraldine S Pinkus, Eren D Yeh, Jane E Brock, Stephanie Schulte, Susan C Lester
Lymphocytic lobulitis (LL) is characterized by prominent lymphocytic infiltrates centered on lobules. Sclerosing lymphocytic lobulitis (SCLL) associated with diabetes mellitus (DM) or autoimmune disease (AI) was the first type to be described. Subsequently, non-sclerosing LL (NSCLL) was reported as an incidental finding in prophylactic mastectomies due to high risk germline mutations or a family history of breast cancer. The two types of LL were distinguished by stromal features and a predominant population of B-cells in the former and T-cells in the latter...
March 20, 2024: Human Pathology
https://read.qxmd.com/read/38517601/lipus-regulates-the-progression-of-knee-osteoarthritis-in-mice-through-primary-cilia-mediated-trpv4-channels
#14
JOURNAL ARTICLE
Sha Wu, Haiqi Zhou, Huixian Ling, Yuyan Sun, Ziyu Luo, ThaiNamanh Ngo, Yuanyuan Fu, Wen Wang, Ying Kong
Osteoarthritis (OA) is a common disease in middle-aged and elderly people. An imbalance in calcium ion homeostasis will contribute to chondrocyte apoptosis and ultimately lead to the progression of OA. Transient receptor potential channel 4 (TRPV4) is involved in the regulation of intracellular calcium homeostasis. TRPV4 is expressed in primary cilia, which can sense mechanical stimuli from outside the cell, and its abnormal expression is closely related to the development of OA. Low-intensity pulsed ultrasound (LIPUS) can alleviate chondrocyte apoptosis while the exact mechanism is unclear...
March 22, 2024: Apoptosis: An International Journal on Programmed Cell Death
https://read.qxmd.com/read/38516813/age-differences-in-generalization-memory-specificity-and-their-overnight-fate-in-childhood
#15
JOURNAL ARTICLE
Elisa S Buchberger, Ann-Kathrin Joechner, Chi T Ngo, Ulman Lindenberger, Markus Werkle-Bergner
Memory enables generalization to new situations, and memory specificity that preserves individual episodes. This study investigated generalization, memory specificity, and their overnight fate in 141 4- to 8-year-olds (computerized memory game; 71 females, tested 2020-2021 in Germany). The results replicated age effects in generalization and memory specificity, and a contingency of generalization on object conceptual properties and interobject semantic proximity. Age effects were stronger in generalization than in memory specificity, and generalization was more closely linked to the explicit regularity knowledge in older than in younger children...
March 22, 2024: Child Development
https://read.qxmd.com/read/38516731/comtrifosides-a-and-b-two-new-triterpenoid-saponins-from-the-leaves-of-combretum-trifoliatum
#16
JOURNAL ARTICLE
Cong Thai Son Nguyen, Thanh Hoa Vo, Nguyen Kim Tuyen Pham, Bui Linh Chi Huynh, Trong Nghia Ngo, Van Son Dang, Thi Kim Chi Huynh, Trong Dat Bui, Diep Xuan Ky Nguyen, Nhat Minh Phan, Dinh Tri Mai, Kim Phi Phung Nguyen, Tan Phat Nguyen
The phytochemical composition of the Combretum trifoliatum leaves was studied for the first time. Two new triterpenoid saponins, named comtrifoside A ( 1 ) and comtrifoside B ( 2 ), together with two other saponins ( 3-4 ) were purified by variously chromatographic techniques. For the first time, compound 3 was informed from the Combretum genus, as well as all of the isolated compounds ( 1-4 ) were reported from C. trifoliatum . The chemical structures of them were clearly characterised using extensive UV-VIS, IR, HRMS-ESI, and NMR experimental data...
March 22, 2024: Natural Product Research
https://read.qxmd.com/read/38513838/landscape-fire-smoke-airway-exposure-impairs-respiratory-and-cardiac-function-and-worsens-experimental-asthma
#17
JOURNAL ARTICLE
Henry M Gomez, Tatt J Haw, Dusan Ilic, Peter Robinson, Chantal Donovan, Amanda J Croft, Kanth S Vanka, Ellen Small, Olivia R Carroll, Richard Y Kim, Jemma R Mayall, Tesfalidet Beyene, Thava Palanisami, Doan Tm Ngo, Graeme R Zosky, Elizabeth G Holliday, Megan E Jensen, Vanessa M McDonald, Vanessa E Murphy, Peter Gibson, Jay C Horvat
BACKGROUND: Millions of people are exposed to landscape fire smoke (LFS) globally and inhalation of LFS particulate matter is associated with poor respiratory and cardiovascular outcomes. However, how LFS affects respiratory and cardiovascular function is less well understood. OBJECTIVE: To characterize the pathophysiological effects of representative LFS airway exposure on respiratory and cardiac function and on asthma outcomes. METHODS: LFS was generated using a customized combustion chamber...
March 19, 2024: Journal of Allergy and Clinical Immunology
https://read.qxmd.com/read/38512836/effective-volume-of-rebreathed-air-during-breathing-with-facepieces-increases-with-protection-class-and-decreases-with-ambient-airflow
#18
JOURNAL ARTICLE
Helen Ngo, Johannes Spaeth, Stefan Schumann
Wearing facepieces is discussed in the context of increasing the volume of rebreathed air. We hypothesized that rebreathed air volume increases with increasing filtering facepiece (FFP) class and that persons breathing via facepieces compensate for the additional dead-space. We have determined the effective amount of rebreathed air for a surgical masks and FFP2 and FFP3 respirators in a physical model and determined tidal volumes, breathing frequency, blood oxygen saturation, and transcutaneously measured blood carbon dioxide partial pressure (PCO2) in lung-healthy subjects breathing without and with facepieces at rest and during exercising on a recumbent ergometer...
2024: PloS One
https://read.qxmd.com/read/38511428/receptors-underlying-an-odorant-s-valence-across-concentrations-in-drosophila-larvae
#19
JOURNAL ARTICLE
Sarah Perry, Jonathan Trevorrow Clark, Paulina Ngo, Anandasankar Ray
Odorants interact with receptors expressed in specialized olfactory neurons, and neurons of the same class send their axons to distinct glomeruli in the brain. The stereotypic spatial glomerular activity map generates recognition and behavioral response for the odorant. The valence of an odorant changes with concentration, typically becoming aversive at higher concentrations. Interestingly in the Drosophila larvae, the odorant (E)-2-hexenal is aversive at low concentrations and attractive at higher concentrations...
March 21, 2024: Journal of Experimental Biology
https://read.qxmd.com/read/38510421/-we-forgot-about-the-donkeys-an-institutional-analysis-of-the-shift-in-animal-welfare-from-direct-implementation-towards-advocacy-based-programming
#20
JOURNAL ARTICLE
Emily Haddy, Leanne Proops, Faith Burden, Zoe Raw, Juliane Kaminski, Julia Brown
Shifts from direct implementation to advocacy-based programming have been documented across many non-governmental organisation (NGO) sectors, including animal welfare. Semi-structured interviews with 32 staff from different positions within animal welfare NGOs explored recent programming changes. Maintaining a balance between direct implementation and advocacy-based activities emerged as a strong theme. The findings suggest that risks are associated with both the direct implementation status quo and transitioning to an advocacy-based focus...
2024: Animal Welfare
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