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Complex regional pain syndrome

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https://www.readbyqxmd.com/read/28934787/complex-regional-pain-syndrome-type-i-a-debilitating-and-poorly-understood-syndrome-possible-role-for-pulsed-electromagnetic-fields-a-narrative-review
#1
Stefania Pagani, Francesca Veronesi, Nicolo Nicoli Aldini, Milena Fini
BACKGROUND: Complex regional pain syndrome type I (CRPS-I), also called algodystrophy, is a complex syndrome characterized by limb pain, edema, allodynia, hyperalgesia and functional impairment of bone with a similar clinical picture of osteoporosis, including an increased release of various pro-inflammatory neuropeptides and cytokines. Several treatments have been proposed for CRPS-I, but due to the poor outcome of conventional drugs and the invasiveness of some techniques, expectations are now directed towards new resources that could be more effective and less invasive...
September 2017: Pain Physician
https://www.readbyqxmd.com/read/28928655/effects-of-simvastatin-beyond-dyslipidemia-exploring-its-antinociceptive-action-in-an-animal-model-of-complex-regional-pain-syndrome-type-i
#2
Graziela Vieira, Juliana Cavalli, Elaine C D Gonçalves, Tainara R Gonçalves, Larissa R Laurindo, Maíra Cola, Rafael C Dutra
Simvastatin is a lipid-lowering agent that blocks the production of cholesterol through inhibition of 3-hydroxy-methyl-glutaryl coenzyme A (HMG-CoA) reductase. In addition, recent evidence has suggested its anti-inflammatory and antinociceptive actions during inflammatory and pain disorders. Herein, we investigated the effects of simvastatin in an animal model of complex regional pain syndrome-type I, and its underlying mechanisms. Chronic post-ischemia pain (CPIP) was induced by ischemia and reperfusion (IR) injury of the left hind paw...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28928497/perianal-abscess-mimicking-levator-ani-syndrome-a-case-report-and-approach-to-the-differential-diagnosis-of-anorectal-pain
#3
Paul Mastragostino, Alexander D Lee, Patrick J Battaglia
OBJECTIVE: To present the clinical management and comprehensive differential diagnosis of a patient with anorectal pain from a perianal abscess. CLINICAL FEATURES: A 41-year-old woman presented with pain localized to her perianal and gluteal region, accompanied by internal and external rectal pain. Prior to presentation, the patient had received a working diagnosis of levator ani syndrome. INTERVENTION AND OUTCOME: An interdisciplinary management approach was utilized...
August 2017: Journal of the Canadian Chiropractic Association
https://www.readbyqxmd.com/read/28914784/antiallodynic-effects-of-bee-venom-in-an-animal-model-of-complex-regional-pain-syndrome-type-1-crps-i
#4
Sung Hyun Lee, Jae Min Lee, Yun Hong Kim, Jung Hyun Choi, Seung Hwan Jeon, Dong Kyu Kim, Hyeon Do Jeong, You Jung Lee, Hue Jung Park
Neuropathic pain in a chronic post-ischaemic pain (CPIP) model mimics the symptoms of complex regional pain syndrome type I (CRPS I). The administration of bee venom (BV) has been utilized in Eastern medicine to treat chronic inflammatory diseases accompanying pain. However, the analgesic effect of BV in a CPIP model remains unknown. The application of a tight-fitting O-ring around the left ankle for a period of 3 h generated CPIP in C57/Bl6 male adult mice. BV (1 mg/kg ; 1, 2, and 3 times) was administered into the SC layer of the hind paw, and the antiallodynic effects were investigated using the von Frey test and by measuring the expression of neurokinin type 1 (NK-1) receptors in dorsal root ganglia (DRG)...
September 15, 2017: Toxins
https://www.readbyqxmd.com/read/28901847/micrornas-to-monitor-pain-migraine-and-drug-treatment
#5
Luca Gallelli, Erika Cione, Maria Cristina Caroleo, Marco Carotenuto, Pasqualina Lagana, Antonio Siniscalchi, Vincenzo Guidetti
Migraine is a prevalent neurovascular disorders with a complex pathophysiology and therapeutic options characterized by important side effects or problems related to drug abuse. No specific biomarkers are recognized to be univocal for this subclinical condition, yet. In this concern microRNAs have been suggested as potentially useful screening/diagnostic tool, and research is underway to recognize the most effective candidate(s). microRNAs, able to regulate immune and neuronal processes are herein reported for both, mice models with multiple induced pain conditions and human subjects...
September 12, 2017: MicroRNA
https://www.readbyqxmd.com/read/28891866/passive-transfer-autoimmunity-in-a-mouse-model-of-complex-regional-pain-syndrome
#6
Tian-Zhi Guo, Xiaoyou Shi, Wen-Wu Li, Tzuping Wei, J David Clark, Wade S Kingery
It has been proposed that Complex Regional Pain Syndrome (CRPS) is a post-traumatic autoimmune disease and we previously observed that B cells are required for the full expression of CRPS-like changes a mouse tibia fracture CRPS model. The current study used the mouse model to evaluate the progression of post-fracture CRPS-like changes in wildtype (WT) and muMT fracture mice lacking B cells and antibodies. The pronociceptive effects of injecting WT fracture mouse serum antibodies into muMT fracture mice were also evaluated...
September 1, 2017: Pain
https://www.readbyqxmd.com/read/28862737/primary-bone-lymphoma-of-the-talus-a-challenging-diagnosis
#7
Ombretta Annibali, Gianluigi Fabbriciani, Mariantonietta Tafuri, Marco Massarotti, Pietro Sedati, Valeria Tomarchio, Sabattini Elena, Pileri Stefano, Carlo Selmi, Giuseppe Avvisati
PURPOSE: Diagnostic challenges are common in clinical practice and diagnostic or classification criteria for musculoskeletal conditions cannot overshadow clinical skills. METHODS: We present the case of a young man who complained of prolonged articular pain and mild swelling of the right ankle in the absence of other remarkable data. Apparently fulfilling the Budapest diagnostic criteria for complex regional pain syndrome, the patient was treated accordingly, but the pain increased over time...
August 28, 2017: Tumori
https://www.readbyqxmd.com/read/28862131/three-cases-of-type-1-complex-regional-pain-syndrome-after-elective-total-hip-replacement
#8
Gerardo Zanotti, Pablo Ariel Slullitel, Fernando Martín Comba, Martín Alejandro Buttaro, Francisco Piccaluga
Complex regional pain syndrome (CRPS) constitutes an atypical cause of pain after orthopaedic procedures. To our knowledge, there is a paucity of literature reporting this syndrome after total hip arthroplasty (THR), since only two case reports have been published. We thenceforth describe the clinical outcome of three cases of type-1 CRPS developed after elective THR, two of them initially diagnosed with secondary osteoarthritis whereas the remaining one presented a sequel of a failed osteosynthesis that required conversion to THR...
2017: SICOT-J
https://www.readbyqxmd.com/read/28856112/the-efficacy-of-systemic-lidocaine-in-the-management-of-chronic-pain-a-literature-review
#9
REVIEW
Fardin Yousefshahi, Oana Predescu, Juan Francisco Asenjo
CONTEXT: Despite recent advances in the understanding of the chronic pain concept, its diagnosis and management remains a daily challenge for clinicians and patients. Based on the published literature, this review discusses and tries to organize the current knowledge and the up-to-date clinical experience about the efficacy and safety of the use of intravenous lidocaine in treatment and prevention of chronic pain. EVIDENCE ACQUISITION: To prepare this narrative review, we performed an in depth literature review using the PubMed searching engine...
June 2017: Anesthesiology and Pain Medicine
https://www.readbyqxmd.com/read/28852115/biased-visuospatial-perception-in-complex-regional-pain-syndrome
#10
Lieve Filbrich, Andrea Alamia, Charlotte Verfaille, Anne Berquin, Olivier Barbier, Xavier Libouton, Virginie Fraselle, Dominique Mouraux, Valéry Legrain
Complex regional pain syndrome (CRPS) is a chronic pain condition associating sensory, motor, trophic and autonomic symptoms in one limb. Cognitive difficulties have also been reported, affecting the patients' ability to mentally represent, perceive and use their affected limb. However, the nature of these deficits is still a matter of debate. Recent studies suggest that cognitive deficits are limited to body-related information and body perception, while not extending to external space. Here we challenge that statement, by using temporal order judgment (TOJ) tasks with tactile (i...
August 29, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28850529/an-exploration-into-the-cortical-reorganisation-of-the-healthy-hand-in-upper-limb-complex-regional-pain-syndrome
#11
Flavia Di Pietro, Tasha R Stanton, G Lorimer Moseley, Martin Lotze, James H McAuley
BACKGROUND AND AIMS: Recent evidence demonstrated that complex regional pain syndrome (CRPS) is associated with a larger than normal somatosensory (S1) representation of the healthy hand. The most intuitive mechanism for this apparent enlargement is increased, i.e. compensatory, use of the healthy hand. We investigated whether enlargement of the S1 representation of the healthy hand is associated with compensatory use in response to CRPS. Specifically, we were interested in whether the size of the S1 representation of the healthy hand is associated with the severity of functional impairment of the CRPS-affected hand...
October 2016: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/28850523/a-randomized-controlled-trial-of-amitriptyline-versus-gabapentin-for-complex-regional-pain-syndrome-type-i-and-neuropathic-pain-in-children
#12
Stephen Brown, Bradley Johnston, Khush Amaria, Jessica Watkins, Fiona Campbell, Carolyne Pehora, Patricia McGrath
BACKGROUND: Treatment of neuropathic pain in children is challenging, and requires a multimodal approach of pharmacologic, physical, and psychological therapies; however there is little evidence to guide practice. Amitriptyline and gabapentin are first-line drugs for treating neuropathic pain in adults, yet no studies have examined their efficacy, or compared them directly, to determine which might be better for pain relief and sleep disturbance in children. METHODS: After informed consent was obtained, 34 patients aged 7-18 years diagnosed with complex regional pain syndrome type I (CRPS I) or a neuropathic pain condition were randomly allocated to receive either amitriptyline or gabapentin...
October 2016: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/28850515/cortical-reorganization-of-the-healthy-hand-in-upper-limb-complex-regional-pain-syndrome-crps-is-reorganizations-of-common-beliefs-about-crps-necessary
#13
Stephen Butler
No abstract text is available yet for this article.
October 2016: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/28850441/the-risk-of-pain-syndrome-affecting-a-previously-non-painful-limb-following-trauma-or-surgery-in-patients-with-a-history-of-complex-regional-pain-syndrome
#14
Ellen S Satteson, Patrick W Harbour, L Andrew Koman, Beth P Smith, Zhongyu Li
BACKGROUND AND PURPOSE: Complex regional pain syndrome (CRPS) is a challenging complication after surgery or trauma. This study sought to determine the incidence of CRPS after a second inciting event in a previously unaffected extremity in patients with a history of an ongoing CRPS diagnosis in another extremity. METHODS: A retrospective review identified patients with CRPS seen in clinic over a 20-month period. The incidence of CRPS after subsequent surgery or injury in a previous unaffected extremity was determined and compared to an average incidence reported in the literature...
January 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/28850440/complex-regional-pain-syndrome-crps-high-risk-of-crps-after-trauma-in-another-limb-in-patients-who-already-have-crps-in-one-hand-or-foot-lasting-changes-in-neural-pain-modulating-systems
#15
https://www.readbyqxmd.com/read/28850424/intrathecal-management-of-complex-regional-pain-syndrome-a-case-report-and-literature
#16
Jonathan M Hagedorn, George Atallah
BACKGROUND AND PURPOSE: Complex regional pain syndrome (CRPS) is a painful condition typically resulting from a traumatic event. Pain control in these patients is often difficult and requires a multimodal approach. Our objectives are to present a single intrathecal pain management regimen for CRPS and provide a literature review of intrathecal pain management options in CRPS. METHODS: Case report from an academic pain management clinic. CASE REPORT: We present the case of a 29-year-old female with a past medical history of multiple lumbar spine surgeries and lumbar post-laminectomy syndrome who presented to clinic with CRPS type II of the bilateral lower extremities...
January 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/28850423/invasive-intervention-for-intractable-complex-regional-pain-syndromes-crps
#17
Harald Breivik
No abstract text is available yet for this article.
January 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/28850342/pain-reduction-due-to-novel-sensory-motor-training-in-complex-regional-pain-syndrome-i-a-pilot-study
#18
Anne-Christine Schmid, Anja Schwarz, Sylvia M Gustin, Joel D Greenspan, Friedhelm C Hummel, Niels Birbaumer
BACKGROUND AND AIMS: Patients suffering from Complex Regional Pain Syndrome (CRPS) of the upper limb show a changed cortical representation of the affected hand. The lip area invades the former hand area contralateral to the affected hand. This change in cortical representation is correlated to the intensity of ongoing pain in patients with CRPS. Further studies revealed that restoration of the original representation coincides with a decrease of pain. Sensory-motor training protocols can increase and/or relocate cortical somatosensory and motor representation areas of the fingers, as shown, for example, in Braille reading individuals and professional violin players...
April 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/28850333/home-training-in-sensorimotor-discrimination-reduces-pain-in-complex-regional-pain-syndrome-crps
#19
Herta Flor
No abstract text is available yet for this article.
April 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/28850332/adolescents-experience-of-complex-persistent-pain
#20
Kari Sørensen, Bjørg Christiansen
BACKGROUND AND AIMS: Persistent (chronic) pain is a common phenomenon in adolescents. When young people are referred to a pain clinic, they usually have amplified pain signals, with pain syndromes of unconfirmed ethology, such as fibromyalgia and complex regional pain syndrome (CRPS). Pain is complex and seems to be related to a combination of illness, injury, psychological distress, and environmental factors. These young people are found to have higher levels of distress, anxiety, sleep disturbance, and lower mood than their peers and may be in danger of entering adulthood with mental and physical problems...
April 2017: Scandinavian Journal of Pain
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