keyword
MENU ▼
Read by QxMD icon Read
search

evidence-based design

keyword
https://www.readbyqxmd.com/read/28922704/direct-acting-antivirals-for-chronic-hepatitis-c
#1
REVIEW
Janus C Jakobsen, Emil Eik Nielsen, Joshua Feinberg, Kiran Kumar Katakam, Kristina Fobian, Goran Hauser, Goran Poropat, Snezana Djurisic, Karl Heinz Weiss, Milica Bjelakovic, Goran Bjelakovic, Sarah Louise Klingenberg, Jian Ping Liu, Dimitrinka Nikolova, Ronald L Koretz, Christian Gluud
BACKGROUND: Millions of people worldwide suffer from hepatitis C, which can lead to severe liver disease, liver cancer, and death. Direct-acting antivirals (DAAs), e.g. sofosbuvir, are relatively new and expensive interventions for chronic hepatitis C, and preliminary results suggest that DAAs may eradicate hepatitis C virus (HCV) from the blood (sustained virological response). Sustained virological response (SVR) is used by investigators and regulatory agencies as a surrogate outcome for morbidity and mortality, based solely on observational evidence...
September 18, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28922553/programmable-nucleic-acid-based-polygons-with-controlled-neuroimmunomodulatory-properties-for-predictive-qsar-modeling
#2
Morgan Brittany Johnson, Justin R Halman, Emily Satterwhite, Alexey V Zakharov, My N Bui, Kheiria Benkato, Victoria Goldsworthy, Taejin Kim, Enping Hong, Marina A Dobrovolskaia, Emil F Khisamutdinov, Ian Marriott, Kirill A Afonin
In the past few years, the study of therapeutic RNA nanotechnology has expanded tremendously to encompass a large group of interdisciplinary sciences. It is now evident that rationally designed programmable RNA nanostructures offer unique advantages in addressing contemporary therapeutic challenges such as distinguishing target cell types and ameliorating disease. However, to maximize the therapeutic benefit of these nanostructures, it is essential to understand the immunostimulatory aptitude of such tools and identify potential complications...
September 18, 2017: Small
https://www.readbyqxmd.com/read/28922307/safe-summers-adapting-evidence-based-injury-prevention-into-a-summer-curriculum
#3
Melody Schaeffer, Claire Cioni, Nicole Kozma, Catherine Rains, Greta Todd
BACKGROUND: Unintentional injury is the leading cause of death for those aged 0 to 19. St. Louis Children's Hospital created Safety Land, a comprehensive injury prevention intervention which is provided during summer months. This program uses a life-size board game to teach safety education to children in ages 5-11. The purpose of this study was to evaluate the effect of Safety Land on safety knowledge in children that participated in the intervention. METHODS: St...
September 15, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28922212/equity-of-physical-characteristics-between-adolescent-males-and-females-participating-in-single-or-mixed-gender-sport
#4
L M Krause, G A Naughton, A C Benson, S Tibbert
PURPOSE: Policies on single or mixed sex junior sports participation continue to be challenged publically and legally. Often challenges relate to perceptions of size and performance variability between adolescent males and females, yet the evidence base behind these challenges lacks recent review and rigor. METHODS: Physical performance was compared between males and females from two groups of younger (<13 years, n = 109, 67% females, 33% males) and older (>13 years, n = 108, 43% females, 57% males) adolescents...
September 12, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28922174/evaluating-the-effectiveness-of-facebook-to-impact-the-knowledge-of-evidence-based-employment-practices-by-individuals-with-traumatic-brain-injury-a-knowledge-translation-random-control-study
#5
Katherine J Inge, Carolyn W Graham, James W McLaughlin, Doug Erickson, Paul Wehman, Hannah E Seward
BACKGROUND: Individuals with traumatic brain injury (TBI) experience difficulty with obtaining and maintaining employment post-injury. Although vocational rehabilitation (VR) can be one option to provide individuals with TBI support and services to lead to successful employment outcomes, information about these services can be difficult and confusing to navigate. Providing information on evidence-based employment practices to individuals with TBI through social media could be an effective approach...
September 14, 2017: Work: a Journal of Prevention, Assessment, and Rehabilitation
https://www.readbyqxmd.com/read/28922158/tailored-and-adaptive-computerized-cognitive-training-in-older-adults-at-risk-for-dementia-a-randomized-controlled-trial
#6
Alex Bahar-Fuchs, Shannon Webb, Lauren Bartsch, Linda Clare, George Rebok, Nicolas Cherbuin, Kaarin J Anstey
BACKGROUND: Computerized Cognitive Training (CCT) has been shown to improve cognitive function in older adults with mild cognitive impairment (MCI) or mood-related neuropsychiatric symptoms (MrNPS), but many questions remain unresolved. OBJECTIVE: To evaluate the extent to which CCT benefits older adults with both MCI and MrNPS, and its effects on meta-cognitive and non-cognitive outcomes, as well as establish whether adapting difficulty levels and tailoring to individuals' profile is superior to generic training...
September 11, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28921996/treatments-for-internet-gaming-disorder-and-internet-addiction-a-systematic-review
#7
Kristyn Zajac, Meredith K Ginley, Rocio Chang, Nancy M Petry
Problems related to excessive use of the Internet and video games have recently captured the interests of both researchers and clinicians. The goals of this review are to summarize the literature on treatment effectiveness for these problems and to determine whether any treatments meet the minimum requirement of an evidence-based treatment as defined by Chambless et al. (1998). Studies of treatments for Internet gaming disorder (IGD) and Internet addiction were examined separately, as past studies have linked IGD to more severe outcomes...
September 18, 2017: Psychology of Addictive Behaviors: Journal of the Society of Psychologists in Addictive Behaviors
https://www.readbyqxmd.com/read/28921886/clinical-practices-and-attitudes-regarding-the-diagnosis-and-management-of-heart-failure-findings-from-the-core-needs-assessment-survey
#8
Jonathan Howlett, Josep Comin-Colet, Kenneth Dickstein, Ahmet Fuat, Gerhard Pölzl, Sean Delaney
AIMS: CORE is a continuing medical education initiative designed to support the evidence-based management of heart failure (HF) in the primary and secondary care settings. The goal of the CORE Needs Assessment Survey is to describe current clinical practice patterns and attitudes among global stakeholders in HF care. METHODS AND RESULTS: The CORE Steering Committee guided the development of survey questions to assess clinical practice, confidence, and attitudes/perceptions among cardiologists, primary care physicians, and nurses involved in HF management...
September 18, 2017: ESC Heart Failure
https://www.readbyqxmd.com/read/28921882/recommendations-for-obesity-prevention-among-adolescents-from-disadvantaged-backgrounds-a-concept-mapping-study-among-scientific-and-professional-experts
#9
D A Kornet-van der Aa, C H van Randeraad-van der Zee, J Mayer, J M Borys, M J M Chinapaw
The present study aimed to enrich the scientific evidence on obesity prevention programmes for adolescents from socio-economically disadvantaged backgrounds with practice-based experiences from both scientific and professional experts in the field of youth obesity prevention. We used the participatory method of concept mapping. Two concept mapping sessions were conducted: one with programme coordinators of national/regional obesity prevention programmes across Europe (n = 8) and one with scientists participating in European obesity prevention projects (n = 5)...
September 18, 2017: Pediatric Obesity
https://www.readbyqxmd.com/read/28921826/growing-evidence-of-the-beneficial-effects-of-a-marine-protein-based-dietary-supplement-for-treating-hair-loss
#10
REVIEW
Carl S Hornfeldt
BACKGROUND: Hair loss is a common condition among women with a range of causes including nutritional deficiencies. AIMS: To review the clinical data supporting the use of an oral marine supplement designed to promote hair growth. PATIENTS/METHODS: Adult women with temporary thinning hair. Following an initial pilot study, five randomized, double-blind studies assessed the effectiveness of the oral marine supplement for promoting hair growth...
September 16, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28921686/the-effects-of-dynamical-synapses-on-firing-rate-activity-a-spiking-neural-network-model
#11
Radwa Khalil, Marie Z Moftah, Ahmed A Moustafa
Accumulating evidence relates the fine-tuning of synaptic maturation and regulation of neural network activity to several key factors, including GABAA signaling and a lateral spread length between neighboring neurons (i.e. local connectivity). Furthermore, a number of studies consider Short-Term synaptic Plasticity (STP) as an essential element in the instant modification of synaptic efficacy in the neuronal network and in modulating responses to sustained ranges of external Poisson Input Frequency (IF). Nevertheless, evaluating the firing activity in response to the dynamical interaction between STP (triggered by ranges of IF), and these key parameters in vitro remains elusive...
September 18, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/28921621/-but-we-want-to-work-the-movement-of-child-workers-in-peru-and-the-actions-for-reducing-child-labor
#12
Isidro Maya Jariego
The program Edúcame Primero (Educate Me First) is an evidence-based practice for eradicating child labor that has been applied with positive results in Colombia, Peru, and several Central American countries. In this article, we describe the difficulties of implementing the program in two poor areas of Lima (Peru) between 2014 and 2016. Specifically, we discuss three ethical challenges faced during the implementation of the program: (a) the existence of a movement of working children that defends the right of children to work; (b) the polarization of some community-based associations and government institutions on how to deal with the problems of working children; and (c) the use of network indicators in the evaluation of the community's level of cohesion...
September 18, 2017: American Journal of Community Psychology
https://www.readbyqxmd.com/read/28921543/language-growth-in-children-with-heterogeneous-language-disorders-a-population-study
#13
Courtenay Frazier Norbury, George Vamvakas, Debbie Gooch, Gillian Baird, Tony Charman, Emily Simonoff, Andrew Pickles
BACKGROUND: Language development has been characterised by significant individual stability from school entry. However, the extent to which trajectories of language growth vary in children with language disorder as a function of co-occurring developmental challenges is a question of theoretical import, with implications for service provision. METHODS: SCALES employed a population-based survey design with sample weighting procedures to estimate growth in core language skills over the first three years of school...
October 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/28921017/the-german-arthroscopy-registry-dart
#14
Ralf Mueller-Rath, Oliver Miltner, Alfred Hochrein, Philipp Niemeyer
In Germany, more than 400,000 arthroscopic procedures are performed each year. The DART registry is designed to study the outcome of arthroscopic procedures of the shoulder, hip, knee and ankle joint under everyday clinical circumstances using patient-reported outcome measures (PROMs). DART aims at identifying patient-specific factors correlated with therapy-associated complications and treatment failure and will help study the influence of concurrent joint diseases and procedures. To achieve these tasks, a Web-based remote data entry system will be applied and adapted to the needs of DART...
September 18, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28920522/constraint-and-multimodal-approaches-to-therapy-for-chronic-aphasia-a-systematic-review-and-meta-analysis
#15
John E Pierce, Maya Menahemi-Falkov, Robyn O'Halloran, Leanne Togher, Miranda L Rose
Aphasia is a significant cause of disability and reduced quality of life. Two speech pathology treatment approaches appear efficacious: multimodal and constraint-induced aphasia therapies. In constraint-induced therapies, non-verbal actions (e.g., gesture, drawing) are believed to interfere with treatment and patients are therefore constrained to speech. In contrast, multimodal therapies employ non-verbal modalities to cue word retrieval. Given the clinical and theoretical implications, a comparison of these two divergent treatments was pursued...
September 18, 2017: Neuropsychological Rehabilitation
https://www.readbyqxmd.com/read/28920396/-inhibition-of-chitin-oligosaccharide-on-dyslipidemia-and-the-potential-molecular-mechanism-exploration
#16
Fanqi Yi, Junping Zheng, Qiongyu Li, Siming Jiao, Yuguang Du, Yun Ye, Hongtao Liu
The inhibitory effect of NACOS on dyslipidemia and potential molecular mechanisms by in vitro and in vivo experiments were investigated. For in vitro study, four experimental groups were designed by using HepG2 cells, including the control group, palmitic acid (PA) treatment alone group, NACOS treatment alone group and NACOS + PA treatment group. For in vivo study, male C57BL/6 mice were divided into four groups (n=5) at random including the normal control group (NCD), high fat diet (HFD) group, NACOS treatment alone group, NACOS+HFD group, which were treated for 20 weeks...
April 25, 2017: Sheng Wu Gong Cheng Xue Bao, Chinese Journal of Biotechnology
https://www.readbyqxmd.com/read/28919943/-identification-of-positive-youth-development-interventions
#17
Lili M Sardiñas, Viviana Padilla, Mari Aponte, Ana Morales Boscio, Coralee Pérez Pedrogo, Betzaida Santiago, Ángela Pérez Morales, Paloma Torres Dávila, Marizaida Sánchez Cesáreo
There are more people in the world in the youth stage of development than in any other stage of development. The youth in Puerto Rico faces many situations that affect their development and readiness for adulthood. Therefore, it's imperative to identify evidence-based positive youth development interventions to develop practices that help young people prevent adverse situations, promote positive experiences and encourage children and young people to be involved and committed. One hundred and forty seven interventions were identified through a traditional scientific literature review...
January 2017: Revista Puertorriqueña de Psicología
https://www.readbyqxmd.com/read/28919408/neural-oscillations-reflect-latent-learning-states-underlying-dual-context-sensorimotor-adaptation
#18
Justin M Fine, Dalton Moore, Marco Santello
Recent studies have suggested that individuals can form multiple motor memories when simultaneously adapting to multiple, but oppositely-oriented perturbations. These findings predict that individuals detect the change in learning context, allowing the selective initialization and update of motor memories. However, previous electrophysiological studies of sensorimotor adaptation have not identified a neural mechanism supporting the detection of a context switch and adaptation to separate contexts. Here, we tested the hypothesis that such a mechanism is identifiable through neural oscillations measured through EEG...
September 14, 2017: NeuroImage
https://www.readbyqxmd.com/read/28919103/alterations-of-musculoskeletal-models-for-a-more-accurate-estimation-of-lower-limb-joint-contact-forces-during-normal-gait-a-systematic-review
#19
REVIEW
F Moissenet, L Modenese, R Dumas
Musculoskeletal modelling is a methodology used to investigate joint contact forces during a movement. High accuracy in the estimation of the hip or knee joint contact forces can be obtained with subject-specific models. However, construction of subject-specific models remains time consuming and expensive. The purpose of this systematic review of the literature was to identify what alterations can be made on generic (i.e. literature-based, without any subject-specific measurement other than body size and weight) musculoskeletal models to obtain a better estimation of the joint contact forces...
September 1, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28918498/modeling-the-decision-of-mental-health-providers-to-implement-evidence-based-children-s-mental-health-services-a-discrete-choice-conjoint-experiment
#20
Charles E Cunningham, Melanie Barwick, Heather Rimas, Stephanie Mielko, Raluca Barac
Using an online, cross sectional discrete choice experiment, we modeled the influence of 14 implementation attributes on the intention of 563 providers to adopt hypothetical evidence-based children's mental health practices (EBPs). Latent class analysis identified two segments. Segment 1 (12%) would complete 100% of initial training online, devote more time to training, make greater changes to their practices, and introduce only minor modifications to EBPs. Segment 2 (88%) preferred fewer changes, more modifications, less training, but more follow-up...
September 16, 2017: Administration and Policy in Mental Health
keyword
keyword
13590
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"