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Kidney stone analysis

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https://www.readbyqxmd.com/read/28070668/what-happens-to-asymptomatic-lower-pole-kidney-stones-smaller-than-10%C3%A2-mm-in-children-during-watchful-waiting
#1
Onur Telli, Nurullah Hamidi, Uygar Bagci, Arif Demirbas, Ahmet Metin Hascicek, Tarkan Soygur, Berk Burgu
BACKGROUND: The optimal management of lower pole kidney (LPK) stones in children is controversial. The aim of this study was to determine the outcomes of children with asymptomatic isolated LPK stones smaller than 10 mm during follow-up. METHODS: A total of 242 patients with 284 stones presenting at our institution between June 2004 and December 2014 with an asymptomatic, single LPK stone with a diameter of <10 mm were enrolled in the study. All children were assigned to receive first-line therapy and then categorized according to the need for medical intervention...
January 9, 2017: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/28063842/relationship-between-urinary-calcium-and-bone-mineral-density-in-patients-with-calcium-nephrolithiasis
#2
Khashayar Sakhaee, Naim M Maalouf, John Poindexter, Beverley Adams-Huet, Orson W Moe
BACKGROUND: Calcium nephrolithiasis is associated with an increased risk of osteoporosis and fracture. Hypercalciuria has been assumed to be pathogenic for bone loss in kidney stone formers (KSF), although this association was shown in small cross-sectional studies. We explored the association of urine calcium (UCaV) with bone mineral density (BMD) in KSF. METHODS: We retrospectively studied BMD in KSF. Excluded were subjects with hypercalcemia, chronic bowel disease, primary hyperparathyroidism, distal renal tubular acidosis or endogenous creatinine clearance <40 ml/min...
January 4, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28058231/incidence-of-kidney-stones-in-kidney-transplant-recipients-a-systematic-review-and-meta-analysis
#3
Wisit Cheungpasitporn, Charat Thongprayoon, Michael A Mao, Wonngarm Kittanamongkolchai, Insara J Jaffer Sathick, Tsering Dhondup, Stephen B Erickson
AIM: To evaluate the incidence and characteristics of kidney stones in kidney transplant recipients. METHODS: A literature search was performed using MEDLINE, EMBASE, and Cochrane Database of Systematic Reviews from the inception of the databases through March 2016. Studies assessing the incidence of kidney stones in kidney transplant recipients were included. We applied a random-effects model to estimate the incidence of kidney stones. RESULTS: Twenty one studies with 64416 kidney transplant patients were included in the analyses to assess the incidence of kidney stones after kidney transplantation...
December 24, 2016: World Journal of Transplantation
https://www.readbyqxmd.com/read/28057990/predictors-of-systemic-inflammatory-response-syndrome-following-percutaneous-nephrolithotomy
#4
Karunamoorthy Ramaraju, Arun Kumar Paranjothi, Dhinakar Babu Namperumalsamy, Ilamparuthi Chennakrishnan
INTRODUCTION AND OBJECTIVES: Sepsis remains one of the dreaded complications of percutaneous nephrolithotomy (PCNL). To analyze prospectively the preoperative and intraoperative factors that predict the occurrence of systemic inflammatory response syndrome (SIRS) in patients undergoing PCNL so that we can aggressively manage those patients from the preoperative period itself and avert the dangerous complications. MATERIALS AND METHODS: A prospective study was carried out between August 2012 and March 2013 including all patients who underwent PCNL...
October 2016: Urology Annals
https://www.readbyqxmd.com/read/28056318/-clinical-characteristics-of-adult-onset-primary-hypoparathyroidism-a-retrospective-analysis-of-200-cases
#5
T T Quan, Y P Li, O Wang, Y Jiang, W B Xia, M Li, X Q Cheng, X W Meng, X P Xing
Objective: To study the clinical characteristics of primary hypoparathyroidism in adults. Methods: The clinical data of 200 cases with adult-onset primary hypoparathyroidism in Peking Union Medical College Hospital during December 1987 to December 2015 were collected and analyzed retrospectively. Among them, 128 cases were followed up for a median period of 3 years. Results: The major manifestations at their first visits were tetany and numbness in the distal extremities(81.5%, 163/200 and 62.0%, 124/200). Thirty-two percent of the cases (62 cases) had history of seizures, and 60...
January 1, 2017: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
https://www.readbyqxmd.com/read/28052698/variation-coefficient-of-stone-density-a-novel-predictor-of-the-outcome-of-extracorporeal-shockwave-lithotripsy
#6
Shimpei Yamashita, Yasuo Kohjimoto, Takashi Iguchi, Satoshi Nishizawa, Akinori Iba, Kazuro Kikkawa, Isao Hara
OBJECTIVES: Although previous studies have indicated that stone heterogeneity can affect shock wave lithotripsy outcomes, there is no established measurement of stone heterogeneity on computed tomography imagery. We investigated whether variation coefficient of stone density can predict shock wave success. MATERIALS AND METHODS: We conducted a retrospective review of 245 patients with urinary calculi who had undergone shock wave lithotripsy. We compared the predictive powers of treatment success between variation coefficient of stone density and other parameters associated with computed tomography attenuation...
January 4, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/28046001/the-diagnosis-and-management-of-patients-with-renal-colic-across-a-sample-of-us-hospitals-high-ct-utilization-despite-low-rates-of-admission-and-inpatient-urologic-intervention
#7
Elizabeth M Schoenfeld, Penelope S Pekow, Meng-Shiou Shieh, Charles D Scales, Tara Lagu, Peter K Lindenauer
OBJECTIVES: Symptomatic ureterolithiasis (renal colic) is a common Emergency Department (ED) complaint. Variation in practice surrounding the diagnosis and management of suspected renal colic could have substantial implications for both quality and cost of care as well as patient radiation burden. Previous literature has suggested that CT scanning has increased with no improvements in outcome, owing at least partially to the spontaneous passage of kidney stones in the majority of patients...
2017: PloS One
https://www.readbyqxmd.com/read/28011229/differential-colony-size-cell-length-and-cellular-proteome-of-escherichia-coli-isolated-from-urine-vs-stone-nidus-of-kidney-stone-patients
#8
Ratree Tavichakorntrakool, Patcharee Boonsiri, Vitoon Prasongwatana, Aroonlug Lulitanond, Chaisiri Wongkham, Visith Thongboonkerd
BACKGROUND: Escherichia coli is associated with kidney stone disease, as a cause or an effect (secondary or recurrent urinary tract infection, UTI). Defining phenotypic or functional differences between E. coli inside stone nidus (ECS, associated with infection-induced stone) and outside the stone (i.e. from urine) (ECU, represented secondary infection) would be helpful to better understand bacterial involvement in this disease. METHODS: ECS and ECU were isolated from 100 stone formers and subjected to antimicrobial susceptibility test, ERIC-PCR genotyping, determination of biofilm formation, bacterial colony size on agar plate and cell length in broth, 2-DE, nanoLC-MS/MS, protein network analysis, and pyruvate dehydrogenase (PDH) activity assay...
December 20, 2016: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/27994857/adenine-phosphoribosyltransferase-deficiency-in-the-united-kingdom-two-novel-mutations-and-a-cross-sectional-survey
#9
Gowrie S Balasubramaniam, Monica Arenas-Hernandez, Emilia Escuredo, Lynette Fairbanks, Tony Marinaki, Sarah Mapplebeck, Michael Sheaff, Michael K Almond
BACKGROUND: Adenine phosphoribosyltransferase deficiency is an inborn error of metabolism that can cause kidney disease from crystalline nephropathy or kidney stones. METHODS: We present three cases from a single centre with varied presentations to illustrate how increasing awareness led to better patient identification. We then undertook a cross-sectional survey of all the patients identified from the Purine Research Laboratory in the UK since 1974. RESULTS: Our index case presented with recurrent nephrolithiasis and was diagnosed on stone analysis, the second case presented with acute kidney injury and the third case was identified from a biopsy undertaken for acute on chronic kidney injury...
December 2016: Clinical Kidney Journal
https://www.readbyqxmd.com/read/27981926/stone-free-rate-after-extracorporeal-shockwave-lithotripsy-in-the-management-of-pediatric-renal-stones-in-lower-pole-and-other-locations-a-comparative-study
#10
Nadeem Iqbal, Shujah Muhammad, Warda Zafar, Ravale Tashfeen, Javaria Faiz, Aisha Hasan, Ijaz Hussain, Saeed Akhter
OBJECTIVE: To determine a difference in the stone-free-rate among different renal locations in children after extracorporeal shockwave lithotripsy (ESWL). STUDY DESIGN: A descriptive study. PLACE AND DURATION OF STUDY: Urology Department, Shifa International Hospital, Islamabad, Pakistan, from January 2007 to June 2015. METHODOLOGY: The study included children who underwent ESWL, divided into three groups based on location of stones in kidney as group A (lower pole stones), group B (upper and mid pole stones) and group C (renal pelvis stone), respectively...
November 2016: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/27970397/tct-222-clinical-outcomes-of-dual-antiplatelet-therapy-after-coronary-stenting-in-patients-with-chronic-kidney-disease-patient-level-meta-analysis-of-4-randomized-clinical-trials
#11
Doyeon Hwang, Joo Myung Lee, Tae-Min Rhee, Jonghanne Park, Kyung Woo Kw Park, Myeong-Ki Hong, Yangsoo Jang, Marco Valgimigli, Antonio Colombo, Martine Gilard, Tullio Palmerini, Gregg Stone, Hyo-Soo Kim
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27960541/high-frequency-dusting-versus-conventional-holmium-laser-lithotripsy-for-intrarenal-and-ureteric-calculi
#12
Roger Li, David Ruckle, Mohamed Keheila, Jonathan Maldonado, Michelle Lightfoot, Muhannad Alsyouf, Alexander Yeo, Samuel R Abourbih, Gaudencio Olgin, Javier L Arenas, D Duane Baldwin
<b>INTRODUCTION</b> The efficiency of holmium laser lithotripsy for urolithiasis depends upon several factors including laser pulse energy and frequency, and stone composition and retropulsion. This study investigates the complex interplay between these factors and quantifies lithotripsy efficiency using different laser settings in a bench-top kidney and ureter model. <b>METHODS</b> In vitro calyceal and ex vivo porcine ureteral models were constructed. Calcium oxalate monohydrate stones were fragmented using a 200 µm laser fiber...
December 13, 2016: Journal of Endourology
https://www.readbyqxmd.com/read/27959841/kidney-stones-composition-frequency-and-relation-to-metabolic-diagnosis
#13
Francisco R Spivacow, Elisa E Del Valle, Ernesto Lores, Paula G Rey
Nephrolithiasis is one of the most frequent urologic diseases. The aim of this paper is to study the composition and frequency of 8854 patient kidney stones and in a subset of them their metabolic risk factors to be related to their type of calculi. Physicochemical and crystallographic methods were used to assess kidney stone composition. In a subset of 715 patients, we performed an ambulatory metabolic protocol with diagnostic purposes. From the total sample 79% of stones were made of calcium salts (oxalate and phosphate), followed by uric acid stones in 16...
2016: Medicina
https://www.readbyqxmd.com/read/27940671/case-report-cystinuria-and-polycystic-kidney-disease
#14
Ajaydeep Sidhu, Angela Mittal, Xamayta Negroni-Balasquide, Alex Constantinescu, Kristin Kozakowski
Cystinuria and polycystic kidney disease are 2 genetic disorders that affect the genitourinary tract but rarely together. This case report presents 2 pediatric patients diagnosed with polycystic kidney disease and cystinuria requiring surgical treatment. Both subjects presented acutely with stone disease. Imaging studies and stone analysis established the diagnoses. Although coexistence of these 2 conditions is rare, cystinuria should be considered in the differential diagnosis when evaluating patients with cystic disease who develop renal calculi...
December 2016: Pediatrics
https://www.readbyqxmd.com/read/27932514/long-term-therapy-with-wu-ling-san-a-popular-antilithic-chinese-herbal-formula-did-not-prevent-subsequent-stone-surgery-a-nationwide-population-based-cohort-study
#15
San-Yuan Wu, Huey-Yi Chen, Kao-Sung Tsai, Jen-Huai Chiang, Chih-Hsin Muo, Fung-Chang Sung, Yung-Hsiang Chen, Wen-Chi Chen
Traditional Chinese herbal medicine (CHM), which is widely used to treat pain and urolithiasis, is a promising therapy for urinary stone prevention. This study investigated the clinical efficacy of a popular CHM, Wu-Ling-San (WLS), in Taiwan for the prophylaxis of recurrent nephrolithiasis as assessed by surgical stone treatment via a nationwide population-based cohort study. The National Health Insurance Research Database, 2000-2010, which included one million patient records. All patients diagnosed with stone disease at the beginning of the study...
2016: Inquiry: a Journal of Medical Care Organization, Provision and Financing
https://www.readbyqxmd.com/read/27931114/factors-associated-with-compliance-in-submitting-24-hour-urine-collections-in-an-underserved-community
#16
Eric M Ghiraldi, Madhumitha Reddy, Tianyu Li, Andrew C Lawler, Justin I Friedlander
PURPOSE: Patients living in underserved areas do regularly express an interest in stone prevention; however, factors limiting participation, aside from obvious cost considerations, are largely unknown. To better understand factors associated with compliance with submitting 24-hour urine collections, we reviewed our patient experience at the kidney stone clinic at a hospital that provides care for an underserved urban community. MATERIALS AND METHODS: A retrospective chart review of patients treated for kidney and/or ureteral stones between August 2014 and May 2016 was performed...
January 5, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/27915449/common-variants-in-cldn14-are-associated-with-differential-excretion-of-magnesium-over-calcium-in-urine
#17
REVIEW
Tanguy Corre, Eric Olinger, Sarah E Harris, Michela Traglia, Sheila Ulivi, Stefania Lenarduzzi, Hendrica Belge, Sonia Youhanna, Natsuko Tokonami, Olivier Bonny, Pascal Houillier, Ozren Polasek, Ian J Deary, John M Starr, Daniela Toniolo, Paolo Gasparini, Peter Vollenweider, Caroline Hayward, Murielle Bochud, Olivier Devuyst
The nature and importance of genetic factors regulating the differential handling of Ca(2+) and Mg(2+) by the renal tubule in the general population are poorly defined. We conducted a genome-wide meta-analysis of urinary magnesium-to-calcium ratio to identify associated common genetic variants. We included 9320 adults of European descent from four genetic isolates and three urban cohorts. Urinary magnesium and calcium concentrations were measured centrally in spot urine, and each study conducted linear regression analysis of urinary magnesium-to-calcium ratio on ~2...
January 2017: Pflügers Archiv: European Journal of Physiology
https://www.readbyqxmd.com/read/27915396/accurate-stone-analysis-the-impact-on-disease-diagnosis-and-treatment
#18
REVIEW
Neil S Mandel, Ian C Mandel, Ann M Kolbach-Mandel
This manuscript reviews the requirements for acceptable compositional analysis of kidney stones using various biophysical methods. High-resolution X-ray powder diffraction crystallography and Fourier transform infrared spectroscopy (FTIR) are the only acceptable methods in our labs for kidney stone analysis. The use of well-constructed spectral reference libraries is the basis for accurate and complete stone analysis. The literature included in this manuscript identify errors in most commercial laboratories and in some academic centers...
December 3, 2016: Urolithiasis
https://www.readbyqxmd.com/read/27914711/proteomic-based-research-strategy-identified-laminin-subunit-alpha-2-as-a-potential-urinary-specific-biomarker-for-the-medullary-sponge-kidney-disease
#19
Antonia Fabris, Maurizio Bruschi, Laura Santucci, Giovanni Candiano, Simona Granata, Alessandra Dalla Gassa, Nadia Antonucci, Andrea Petretto, Gian Marco Ghiggeri, Giovanni Gambaro, Antonio Lupo, Gianluigi Zaza
Medullary sponge kidney (MSK) disease, a rare kidney malformation featuring recurrent renal stones and nephrocalcinosis, continues to be diagnosed using expensive and time-consuming clinical/instrumental tests (mainly urography). Currently, no molecular diagnostic biomarkers are available. To identify such we employed a proteomic-based research strategy utilizing urine from 22 patients with MSK and 22 patients affected by idiopathic calcium nephrolithiasis (ICN) as controls. Notably, two patients with ICN presented cysts...
November 30, 2016: Kidney International
https://www.readbyqxmd.com/read/27885825/multiphase-fluid-solid-coupled-analysis-of-shock-bubble-stone-interaction-in-shockwave-lithotripsy
#20
K G Wang
A novel multiphase fluid-solid coupled computational framework is applied to investigate the interaction of a kidney stone immersed in liquid with a lithotripsy shock wave (LSW) and a gas bubble near the stone. The main objective is to elucidate the effects of a bubble in the shock path to the elastic and fracture behaviors of the stone. The computational framework couples a finite volume two-phase computational fluid dynamics (CFD) solver with a finite element (FE) computational solid dynamics (CSD) solver...
November 24, 2016: International Journal for Numerical Methods in Biomedical Engineering
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