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Kidney stone analysis

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https://www.readbyqxmd.com/read/29133141/abdominal-fat-pad-excisional-biopsy-for-the-diagnosis-and-typing-of-systemic-amyloidosis
#1
Yessica Garcia, A Bernard Collins, James R Stone
In the past, the diagnosis and typing of amyloidosis often required an invasive biopsy of an internal organ, such as the heart or kidneys. Abdominal fat pad excisional biopsy (FPEB) offers a less invasive approach, but the sensitivity of this technique has been unclear. To determine the sensitivity of FPEB for immunoglobulin light chain (AL) and transthyretin (ATTR) amyloidosis, we performed a retrospective clinicopathologic analysis of 97 patients who had undergone FPEB, of which 16 were positive for amyloid...
November 10, 2017: Human Pathology
https://www.readbyqxmd.com/read/29130676/-the-feasibility-of-ct-attenuation-value-to-predict-the-composition-of-upper-urinary-calculi-and-success-rate-of-extracorporeal-shock-wave-lithotripsy
#2
Yu Fan, Zhen-Hua Liu, Qiang Wei, Zhuang Tang, Liang-Ren Liu, Bi-Hua Ren, Xiang Li, Yi-Ge Bao, Lu Yang
OBJECTIVE: To explore the feasibility of CT attenuation value (CTvalue) to predict the composition of upper urinary calculi and the number of shock waves (NSW) and success rate (SR) of extracorporeal shock wave lithotripsy (ESWL). METHODS: A total of 146 patients with upper urinary calculi treated by ESWL were included. CT scan was performed before ESWL. Upper urinary calculi with the maximum diameters of less than or equal to 2 cm were included. Infrared spectroscopy was used to analyze the composition of calculi...
September 2017: Sichuan da Xue Xue Bao. Yi Xue Ban, Journal of Sichuan University. Medical Science Edition
https://www.readbyqxmd.com/read/29125974/investigations-of-trace-and-toxic-elements-of-kidney-stones-from-two-different-sudanese-areas-by-%C3%A2%C2%B5-pixe-using-nuclear-microprobe-nmp
#3
REVIEW
M E M Eisa, C A Pineda-Vargas, Sami E E Salah, A L Rodgers
In this study 14 kidney stones (oxalate and phosphate stones) collected from two Sudanese hospitals Particle Induced X ray Emission (µ-PIXE). This technique was used to investigate the matrix as well as the trace element compositions of kidney stones on a microscopic scale using 1.5MeV proton energy. Significant differences in elements content across the groups were found by applying statistical methods. Trace elements such as P,Ca, Fe, Ni, Cu, Zn, Se, Sr, Br, and Pb showed a possible linear relationship of the mean profile for trace elements for each group of stones...
October 18, 2017: Applied Radiation and Isotopes
https://www.readbyqxmd.com/read/29124877/sporadic-primary-hyperparathyroidism-and-stone-disease-a-comprehensive-metabolic-evaluation-before-and-after-parathyroidectomy
#4
Giovanni S Marchini, Kauy V M Faria, Fábio C M Torricelli, Manoj Monga, Miguel Srougi, William C Nahas, Eduardo Mazzucchi
OBJECTIVES: to characterize the stone risk and the impact of parathyroidectomy on the metabolic profile of patients with primary hyperparathyroidism (PHPT) and urolithiasis. SUBJECTS AND METHODS: We analyzed the prospectively collected charts of patients treated at our stone clinic from Jan/2001-Jan/2016 searching for patients with PHPT and urolithiasis. Imaging evaluation of the kidneys, bones and parathyroid glands were assessed. We analyzed the demographic data, serum and urinary parameters before and after parathyroidectomy...
November 10, 2017: BJU International
https://www.readbyqxmd.com/read/29102914/bergenia-ciliata-a-comprehensive-review-of-its-traditional-uses-phytochemistry-pharmacology-and-safety
#5
REVIEW
Mushtaq Ahmad, Maryam Akram Butt, Guolin Zhang, Shazia Sultana, Akash Tariq, Muhammad Zafar
Bergenia ciliata is a medicinal plant used for the treatment of kidney stones. The presented review is the first attempt to gather utmost information about the distribution, ethno-medicines, phytochemical analysis, pharmacology and toxicology of B. ciliata. This review was designed with the aim to compile fragmented information about B. ciliata in addition to explore its therapeutic potential and future research opportunities. A total of 185 research papers were reviewed using several data sources such as; Web of Science, Scopus, Google scholar, Science direct and PubMed...
November 2, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29091707/transcriptional-study-of-hyperoxaluria-and-calcium-oxalate-nephrolithiasis-in-male-rats-inflammatory-changes-are-mainly-associated-with-crystal-deposition
#6
Sunil Joshi, Wei Wang, Saeed R Khan
Hyperoxaluria associated with renal deposition of calcium oxalate (CaOx) crystals causes renal injury and inflammation leading to number of diseases including chronic kidney disease (CKD). It is however, not been possible to separate the renal consequences of hyperoxaluria from that of CaOx crystal deposition. We decided to utilize ethylene glycol (EG) model where hyperoxaluria and CaOx crystal deposition can be separated in time. To test our hypothesis, male rats were made hyperoxaluric by administering EG, rats were euthanized and kidneys were extracted on day 14, when occasional crystal is seen in the kidneys and day 28, when all animals have developed renal CaOx crystal deposits...
2017: PloS One
https://www.readbyqxmd.com/read/29073769/retrospective-cost-analysis-of-a-single-center-reusable-flexible-ureterorenoscopy-program-a-comparative-cost-simulation-of-disposable-furs-as-an-alternative
#7
Tomasz Ozimek, Michael H Schneider, Marie C Hupe, Judith R Wiessmeyer, Jens Cordes, Piotr L Chlosta, Axel S Merseburger, Mario Wolfgang Kramer
OBJECTIVE: The increasing number of flexible ureterorenoscopy (fURS) procedures, the fragility of devices, and their growing maintenance and repair costs represent a substantial burden for urologic departments. Disposable single-use fURS devices offer many advantages over reusable fURS. Among them, the LithoVue™ model shows the best clinical utility. In our study, we assessed the economic aspects of reusable fURS application compared with the potential costs and benefits of single-use fURS (LithoVue™)...
November 17, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/29069011/clinical-efficacy-of-percutaneous-nephrolithotomy-versus-retrograde-intrarenal-surgery-for-pediatric-kidney-urolithiasis-a-prisma-compliant-article
#8
REVIEW
Pei Lu, Rijin Song, Yuzhou Yu, Jie Yang, Kai Qi, Rongzhen Tao, Keliang Chen, Wei Zhang, Min Gu
BACKGROUND: Percutaneous nephrolithotomy (PCNL) and retrograde intrarenal surgery (RIRS) are widely used for pediatric upper tract stones; however, comparisons of their clinical efficacies are needed. METHODS: Literature searches for relevant articles were performed using PubMed, the Cochrane Central Register of Controlled Trials, Embase and the China CNKI database. Study quality was assessed by Jadad and Newcastle-Ottawa Scales. Standard mean differences (SMDs) or odds ratios (OR), and 95% confidential intervals (95% CIs) were pooled for meta-analysis...
October 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29067044/acute-kidney-injury-in-ureteric-stones-single-centre-short-term-analysis
#9
Huma Mamun Mahmud, Syed Mamun Mahmud
OBJECTIVE: To analyze acute kidney injury (AKI) frequency, risk factors and outcome in ureteric stone patients. METHODS: This is an observational retrospective study performed in a single tertiary care centre in Abu Dhabi from October 2014 till August 2015. Convenient sampling was done on 152 consecutive patients who underwent decompression surgery (Ureterorenoscopy LASER Lithotripsy and DJ Stenting) for ureteric stones. Serum Creatinine was used to calculate creatinine clearance by cock croft Gault formula in all patients before and after procedure...
July 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/29058024/management-of-renal-transplant-urolithiasis-a-multicentre-study-by-the-french-urology-association-transplantation-committee
#10
J Branchereau, M O Timsit, Y Neuzillet, T Bessède, R Thuret, M Gigante, X Tillou, R Codas, J Boutin, A Doerfler, F Sallusto, T Culty, V Delaporte, N Brichart, B Barrou, L Salomon, G Karam, J Rigaud, L Badet, F Kleinklauss
PURPOSE: Urolithiasis is rare among renal transplant recipients and its management has not been clearly defined. METHODS: This multicentre retrospective study was organised by the Comité de Transplantation de l'Association Française d'Urologie (French Urology Association transplantation committee). Statistical analysis was performed with SPSS 19 software. RESULTS: Ninety-five patients were included in this study. Renal transplant urolithiasis was an incidental finding in 55% of cases, mostly on a routine follow-up ultrasound examination...
October 22, 2017: World Journal of Urology
https://www.readbyqxmd.com/read/29054323/human-kidney-stone-matrix-latent-potential-to-restrain-com-induced-cytotoxicity-and-inflammatory-response
#11
Shifa Narula, Simran Tandon, Prakash Baligar, Shrawan Kumar Singh, Chanderdeep Tandon
Kidney stone disease is a multi-factorial disorder resulting from the interplay of various risk factors including lifestyle, environment and genetics along with metabolic activities inside the body. However, it is difficult to determine how these factors converge to promote stone disease. Extensive investigations of kidney stone composition at the molecular level have been carried out however; its impact on the complex mechanism of stone formation is still obscure. Hence, an in vitro study was designed to investigate the attenuation of calcium oxalate toxicity by human kidney stone matrix proteins on NRK-52E cells using flowcytometry, Western blotting, RT-PCR and immunofluorescence assays...
October 18, 2017: Chemico-biological Interactions
https://www.readbyqxmd.com/read/29027695/shear-wave-elastographic-alterations-in-the-kidney-after-extracorporeal-shock-wave-lithotripsy
#12
Rustu Turkay, Ercan Inci, Derya Bas, Arda Atar
OBJECTIVES: Extracorporeal shock wave lithotripsy (ESWL) is a method used frequently for the treatment of renal stone disease. Although its safety is proven, there are still concerns about its unwanted effects on kidneys. In this prospective study, we aimed to evaluate renal tissue alterations with shear wave elastography (SWE) after ESWL. We also studied the correlation between SWE and resistive index (RI) changes. METHODS: The study included 59 patients who underwent ESWL treatment for renal stone disease...
October 13, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28992566/quantification-of-xanthine-and-uric-acid-related-compounds-in-urine-using-a-dilute-and-shoot-technique-coupling-ultra-high-performance-liquid-chromatography-and-high-resolution-orbitrap-mass-spectrometry
#13
Adrian Rodriguez, Rosa Maria Gomila, Gabriel Martorell, Antonia Costa-Bauza, Felix Grases
Quantitative analysis of relevant metabolites in biofluids such as urine is often a tedious procedure, since it usually requires extraction, purification or preconcentration. For instance, in the analysis of methylxanthines in urine, a solid-phase extraction is often required. In the current work, a rapid and highly sensitive "dilute-and-shoot" method combining ultra-high-performance liquid chromatography and high-resolution mass spectrometry (UHPLC/HRMS) was validated for urinary determination of twelve analytes: uric acid, hypoxanthine, xanthine, 1-methyluric acid, 1,3-dimethyluric acid, 1-methylxanthine, 3-methylxanthine, 7-methylxanthine, theophylline, theobromine, paraxanthine and caffeine...
November 1, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/28992172/points-to-consider-in-renal-involvement-in-systemic-sclerosis
#14
REVIEW
Felice Galluccio, Ulf Müller-Ladner, Daniel E Furst, Dinesh Khanna, Marco Matucci-Cerinic
This article discusses points to consider when undertaking a clinical trial to test therapy for renal involvement in SSc, not including scleroderma renal crisis. Double-blind, randomized controlled trials vs placebo or standard background therapy should be strongly considered. Inclusion criteria should consider a pre-specified range of renal functions or stratification of renal function. Gender and age limitations are probably not necessary. Concomitant medications including vasodilators, immunosuppressants and endothelin receptor antagonists and confounding illnesses such as diabetes, kidney stones, hypertension and heart failure need to be considered...
September 1, 2017: Rheumatology
https://www.readbyqxmd.com/read/28975110/nephrolithiasis-as-a-common-urinary-system-manifestation-of-inflammatory-bowel-diseases-a-clinical-review-and-meta-analysis
#15
REVIEW
Mahboube Ganji-Arjenaki, Hamid Nasri, Mahmoud Rafieian-Kopaei
CONTEXT: The extra-intestinal manifestations of inflammatory bowel disease (IBD) are common and involve other organs or systems for example; urinary system. EVIDENCE ACQUISITIONS: For this review, we used a variety of sources by searching through Web of Science, PubMed, EMBASE, Scopus and directory of open access journals (DOAJ). RESULTS: Urinary complications may occur in up to 22% of patients and nephrolithiasis or renal/kidney stones have been suggested to be a common manifestation of disease in forms of uric acid, calcium phosphate or calcium oxalate...
July 2017: Journal of Nephropathology
https://www.readbyqxmd.com/read/28966022/pediatric-hospitalizations-for-upper-urinary-tract-calculi-epidemiological-and-treatment-trends-in-the-united-states-2001-2014
#16
Parth K Modi, Young Suk Kwon, Rachel B Davis, Sammy E Elsamra, Viktor Dombrovskiy, Ephrem O Olweny
INTRODUCTION: The incidence of urolithiasis in the pediatric population in the United States has steadily been increasing over the past few decades. Few studies to date have examined trends in the hospitalization and inpatient surgical treatment of urolithiasis in the pediatric population using nationally representative data. OBJECTIVE: The aim was to evaluate nationwide trends in the rates of pediatric hospitalization and inpatient surgical activity for upper urinary tract calculi (UUTC) in the United States from 2001 to 2014...
September 7, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28950716/different-tract-sizes-of-miniaturized-percutaneous-nephrolithotomy-versus-retrograde-intrarenal-surgery-a-systematic-review-and-meta-analysis
#17
Xiao-Shuai Gao, Bang-Hua Liao, Yun-Tian Chen, Shi-Jian Feng, Rang Gao, De-Yi Luo, Jia-Ming Liu, Kun-Jie Wang
PURPOSE: Miniaturized percutaneous nephrolithotomy (MPCNL), including minipercutaneous nephrolithotomy (PCNL), ultramini-PCNL, and micro-PCNL, have been developed recently. The aim of this meta-analysis was to compare the safety and efficacy of different tract sizes of MPCNL with retrograde intrarenal surgery (RIRS) in the management of kidney stones. MATERIALS AND METHODS: We searched PubMed, Embase, and Web of Science to identify case-control trials and randomized controlled trials, which evaluated MPCNL vs RIRS before February 2017...
November 2017: Journal of Endourology
https://www.readbyqxmd.com/read/28900379/postmenopausal-hormone-and-the-risk-of-nephrolithiasis-a-meta-analysis
#18
Juan Yu, Binyan Yin
Menopause is reported to be associated with increased urinary calcium excretion, which may enhance the risk for the development of calcium kidney stones. However, it remains controversial about whether high level of postmenopausal hormone (PMH) is a risk factor for formation of nephrolithiasis. Several observational studies have shown that PMH is protective based on 24-hour urinary parameters. Recent clinical trials provided evidence to conclude that estrogen therapy increases the risk of nephrolithiasis in healthy postmenopausal women...
2017: EXCLI journal
https://www.readbyqxmd.com/read/28890392/natural-history-and-predictors-of-parastomal-hernia-after-robot-assisted-radical-cystectomy-and-ileal-conduit-urinary-diversion
#19
Ahmed A Hussein, Youssef E Ahmed, Paul May, Taimoor Ali, Basim Ahmad, Sana Raheem, Kevin Stone, Adam Hasasnah, Omer Rana, Adam Cole, Derek Wang, Peter Loud, Khurshid A Guru
INTRODUCTION: We investigated the prevalence, variables associated with parastomal hernia (PSH), and its outcomes of after robot-assisted radical cystectomy (RARC) and ileal conduit (IC) for bladder cancer. METHODS: Retrospective review of RARC at our institution was conducted. PSH was defined as protrusion of abdominal contents through the stoma defect in the abdominal wall on cross sectional imaging. PSH was further described in terms of patient and hernia characteristics, symptoms, management and outcomes...
September 7, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28887264/toe-pressures-are-superior-to-duplex-parameters-in-predicting-wound-healing-following-toe-and-foot-amputations
#20
Patrick A Stone, Alexis Glomski, Stephanie N Thompson, Elliott Adams
BACKGROUND: No criteria, including preamputation vascular diagnostic thresholds, have been established to reliably predict healing versus nonhealing following minor lower extremity amputations. Thus, the goal of our study was to identify clinical factors, including noninvasive vascular laboratory measures, associated with wound healing following toe, forefoot, and midfoot amputations. METHODS: We retrospectively examined records of patients receiving elective toe, forefoot, or midfoot amputation at our institution over a 5-year span (2010-2015)...
September 6, 2017: Annals of Vascular Surgery
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