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Postpartum depression

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https://www.readbyqxmd.com/read/28319697/genetic-variants-of-the-kynurenine-3-monooxygenase-and-postpartum-depressive-symptoms-after-cesarean-section-in-chinese-women
#1
Sai-Ying Wang, Kai-Ming Duan, Xiao-Fang Tan, Ji-Ye Yin, Xiao-Yuan Mao, Wei Zheng, Chun-Yan Wang, Mi Yang, Cheng Peng, Hong-Hao Zhou, Zhao-Qian Liu
BACKGROUND: New conceptualizations of depression have emphasized the role of the kynurenine pathway (KP) in the pathogenesis of postpartum depressive symptoms (PDS). Kynurenine 3-monooxygenase (KMO) is a rate-limiting enzyme of the KP, where it catalyzes the conversion of kynurenine (KYN) to 3-hydroxykynurenine (3-HK). Previous work indicates that KMO is closely linked to the pathophysiology of depressive disorders. The purpose of this study is to investigate whether variations in the KMO gene affect PDS development after cesarean section...
March 10, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28319693/what-do-dads-want-treatment-preferences-for-paternal-postpartum-depression
#2
Emily E Cameron, Dana Hunter, Ivan D Sedov, Lianne M Tomfohr-Madsen
BACKGROUND: Postpartum depression (PPD) is prevalent, occurring in 8 to 13% of new fathers. Identifying effective and acceptable treatments for paternal PPD is important to prevent negative family outcomes. Participation in a patient preferred treatment for depression increases treatment adherence and effectiveness. Thus, developing and delivering interventions that are preferred by the target population is an important aspect of successful treatment. The current study investigated treatment preferences for paternal PPD...
March 9, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28319692/development-and-properties-of-a-brief-scale-to-assess-intimate-partner-relationship-in-the-postnatal-period
#3
Karen Wynter, Thach Duc Tran, Heather Rowe, Jane Fisher
BACKGROUND: Poor quality intimate partner relationship is associated with postnatal depression and anxiety among women. Existing scales assessing the quality of this relationship are long and measure stable aspects of the relationship rather than specific behaviours which may respond to targeted interventions. The aim was to develop and investigate the properties of a brief, life stage-specific scale to assess potentially modifiable partner behaviours in the postpartum period. METHODS: Participants were primiparous women from diverse geographical and socio-economic backgrounds in Victoria, Australia...
March 14, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28315630/risk-factors-for-depressive-symptoms-in-early-postpartum-period-and-after-puerperium-are-they-the-same
#4
(no author information available yet)
OBJECTIVES: Correlation between the occurrence of postnatal depressive symptoms at 5 days and 6 weeks postpartum is well established. The objective of the study was to determine the influence of psychosocial and perinatal factors on the occurrence of postpartum depressive symptoms 2 to 5 days and 6 weeks after delivery. METHODS: 373 women in early postpartum (EPG) and 107 women 6 weeks after delivery (late postpartum group - LPG) completed a questionnaire including questions concerning mothers' characteristics, obstetric and neonatal complications during pregnancy, psychiatric factors and Edinburgh Postnatal Depression Scale (EPDS)...
November 19, 2016: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28301335/interdisciplinary-collaboration-in-maternal-mental-health
#5
Nancy Selix, Erin Henshaw, Alinne Barrera, Luba Botcheva, Erin Huie, Gabrielle Kaufman
One out of every five to seven births is affected by postpartum depression, making it the most common maternal health problem in the first year after childbirth. Early identification and treatment are essential, though screening and treatment rates are low. Factors that inhibit effective screening and treatment include lack of uniform screening policies in all maternal health settings, poor coordination of care between primary care and mental health services, coordination of community education efforts and resources, social stigma surrounding mental health treatment, and ineffective application of research and technology in the clinical setting...
March 15, 2017: MCN. the American Journal of Maternal Child Nursing
https://www.readbyqxmd.com/read/28300619/brain-neurotransmitters-in-an-animal-model-with-postpartum-depressive-like-behavior
#6
Y Avraham, Y Hants, L Vorobeiv, M Premishlano, Wiessam Abu Ahmad, D Mankuta, E Galun, S Arbel-Alon
Post-Partum Depression (PPD) occurs in 15% of pregnancies and its patho-physiology is not known. We studied female BALB/c ("depressive") and C57BL/6 (control) mice as a model for PPD and assessed their behavior and correlates with brain neurotransmitters (NTs) - norepinephrine, dopamine, serotonin and intermediates, during the pre-pregnancy (PREP), pregnancy (PREG) and post-Partum (PP) periods. Depressive-like behavior was evaluated by the Open Field (OFT), Tail Suspension (TST) and Forced Swim (FST) tests...
March 11, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28297589/prospective-longitudinal-study-of-predictors-of-postpartum-onset-depression-in-women-with-a-history-of-major-depressive-disorder
#7
Rita Suri, Zachary N Stowe, Lee S Cohen, D Jeffrey Newport, Vivien K Burt, Ana R Aquino-Elias, Bettina T Knight, Jim Mintz, Lori L Altshuler
OBJECTIVE: Risk factors for postpartum depression in euthymic pregnant women with histories of major depressive disorder (MDD) were evaluated. METHODS: From April 2003 to March 2009, 343 pregnant women with a history of Structured Clinical Interview for DSM-IV (SCID)-diagnosed major depressive disorder were prospectively assessed from the third trimester into the postpartum period using the SCID mood module and 17-item Hamilton Depression Rating Scale (HDRS). Data from 300 subjects who completed at least 2 mood module assessments (1 within 60 days before and the other within 60 days after delivery) were analyzed for predictive associations between variables assessed in the third trimester and the development of a postpartum depression...
March 14, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28295746/posttraumatic-stress-disorder-in-the-perinatal-period-pptsd-a-concept-analysis
#8
REVIEW
Julie Vignato, Jane M Georges, Ruth A Bush, Cynthia D Connelly
AIMS AND OBJECTIVES: To report an analysis of the concept of perinatal posttraumatic stress disorder (PPTSD). BACKGROUND: Prevalence of PPTSD is rising in the United States, with 9% of the U.S. perinatal population diagnosed with the disorder and an additional 18% being at risk for the condition. Left untreated, adverse maternal-child outcomes result in increased morbidity, mortality, and healthcare costs. DESIGN: Concept analysis via Walker and Avant's approach...
March 15, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28289215/selective-dietary-supplementation-in-early-postpartum-is-associated-with-high-resilience-against-depressed-mood
#9
Yekta Dowlati, Arun V Ravindran, Zindel V Segal, Donna E Stewart, Meir Steiner, Jeffrey H Meyer
Medical research is moving toward prevention strategies during prodromal states. Postpartum blues (PPB) is often a prodromal state for postpartum depression (PPD), with severe PPB strongly associated with an elevated risk for PPD. The most common complication of childbearing, PPD has a prevalence of 13%, but there are no widespread prevention strategies, and no nutraceutical interventions have been developed. To counter the effects of the 40% increase in monoamine oxidase A (MAO-A) levels that occurs during PPB, a dietary supplement kit consisting of monoamine precursor amino acids and dietary antioxidants was created...
March 13, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28287802/depressive-symptoms-and-gestational-length-among-pregnant-adolescents-cluster-randomized-control-trial-of-centeringpregnancy%C3%A2-plus-group-prenatal-care
#10
Jennifer N Felder, Elissa Epel, Jessica B Lewis, Shayna D Cunningham, Jonathan N Tobin, Sharon Schindler Rising, Melanie Thomas, Jeannette R Ickovics
OBJECTIVES: Depressive symptoms are associated with preterm birth among adults. Pregnant adolescents have high rates of depressive symptoms and low rates of treatment; however, few interventions have targeted this vulnerable group. Objectives are to: (a) examine impact of CenteringPregnancy® Plus group prenatal care on perinatal depressive symptoms compared to individual prenatal care; and (b) determine effects of depressive symptoms on gestational age and preterm birth among pregnant adolescents...
March 13, 2017: Journal of Consulting and Clinical Psychology
https://www.readbyqxmd.com/read/28285186/inflammatory-markers-in-late-pregnancy-in-association-with-postpartum-depression-a-nested-case-control-study
#11
Emma Bränn, Fotios Papadopoulos, Emma Fransson, Richard White, Åsa Edvinsson, Charlotte Hellgren, Masood Kamali-Moghaddam, Adrian Boström, Helgi B Schiöth, Inger Sundström-Poromaa, Alkistis Skalkidou
Recent studies indicate that the immune system adaptation during pregnancy could play a significant role in the pathophysiology of perinatal depression. The aim of this study was to investigate if inflammation markers in a late pregnancy plasma sample can predict the presence of depressive symptoms at eight weeks postpartum. Blood samples from 291 pregnant women (median and IQR for days to delivery, 13 and 7-23days respectively) comprising 63 individuals with postpartum depressive symptoms, as assessed by the Edinburgh postnatal depression scale (EPDS≥12) and/or the Mini International Neuropsychiatric Interview (M...
February 28, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28282707/post-partum-depression-effect-on-child-health-and-development
#12
Fatemeh Abdollahi, Farideh Rezai Abhari, Mehran Zarghami
While studies have shown the disastrous effects of post-partum depression (PPD) on children's behaviors, there is relatively lack of reliable data in Asian countries. This study examined the relative significance of maternal PPD in children's developmental disabilities at age four. In a longitudinal study design (2009), 1801 pregnant women attending in primary health centers of Mazandaran province in the north of Iran provided self-reports of depression from two to twelve postpartum weeks using Edinburgh Postnatal Depression Scale (EPDS)...
February 2017: Acta Medica Iranica
https://www.readbyqxmd.com/read/28282596/childhood-maltreatment-postnatal-distress-and-the-protective-role-of-social-support
#13
K Schury, J Zimmermann, M Umlauft, A L Hulbert, H Guendel, U Ziegenhain, I-T Kolassa
The postpartum period is a vulnerable period for women with a history of childhood maltreatment. This study investigated the association between childhood maltreatment and postnatal distress three months postpartum and examined the role of social support provided by different sources (intimate partner, parents, parents-in-law, and friends). Analyses are based on N=66 women, who were screened for maltreatment experiences shortly after parturition with the Childhood Trauma Questionnaire. Their levels of postnatal distress (symptoms of depression, anxiety, and stress; assessed with the Hospital Anxiety and Depression Scale and the 4-Item version of the Perceived Stress Scale) and postpartum social support (measured with the Postpartum Social Support Questionnaire) were assessed three months postpartum...
March 9, 2017: Child Abuse & Neglect
https://www.readbyqxmd.com/read/28278440/lower-allopregnanolone-during-pregnancy-predicts-postpartum-depression-an-exploratory-study
#14
Lauren M Osborne, Fiona Gispen, Abanti Sanyal, Gayane Yenokyan, Samantha Meilman, Jennifer L Payne
Current evidence is mixed on the role of progesterone and its metabolites in perinatal mood and anxiety disorders. We measured second and third trimester (T2 and T3) progesterone (PROG) and allopregnanolone (ALLO) levels by ELISA and postpartum depression (PPD) by clinician interview (DSM-IV criteria) in 60 pregnant women with a prior diagnosis of a mood disorder. Methods included multivariate and logistic regression with general linear mixed effect models. We found that, after adjustment, every additional ng/mL of T2 ALLO resulted in a 63% (95% CI 13% to 84%, p=0...
February 16, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28278021/exercise-as-an-adjunct-treatment-for-postpartum-depression-for-women-living-in-an-inner-city-a-pilot-study
#15
Jacky Forsyth, Elizabeth Boath, Carol Henshaw, Hannah Brown
To examine the effectiveness of exercise in the management of postpartum depression, women living in an inner-city, who were diagnosed using the Structured Clinical Interview for DSM-IV (Perinatal Version) (SCID-PN), were randomly assigned to an exercise group (N = 12) or control group (N = 12). A focus group was carried out to explore women's views of the trial. There were no significant differences between the two groups for SCID-PN. Although women who had engaged in the exercise viewed it positively (based on focus group data), low adherence to exercise meant that significant improvements in postpartum depression were not found...
February 14, 2017: Health Care for Women International
https://www.readbyqxmd.com/read/28277156/maternal-self-efficacy-postpartum-depression-and-their-relationship-with-functional-status-in-iranian-mothers
#16
Fahimeh Fathi, Sakineh Mohammad-Alizadeh-Charandabi, Mojgan Mirghafourvand
Readiness to care for family, infant, and self are important during the postpartum period. The objective of this study was to determine the relationships of self-efficacy and postpartum depressive symptoms with functional status in randomly sampled Iranian mothers (n = 437). The study was cross-sectional and conducted in 2015. The mean (SD) of the total functional status score was 2.3 (0.2) out of a possible score of 1-4. The maximum and minimum scores in infant care were 4.0 and 2.2 and, in social and community activity, levels were 3...
February 7, 2017: Women & Health
https://www.readbyqxmd.com/read/28276086/a-randomized-controlled-trial-to-examine-the-effectiveness-of-the-home-but-not-alone-mobile-health-application-educational-programme-on-parental-outcomes
#17
Shefaly Shorey, Ying Y Lau, Cindy-Lee Dennis, Yah Shih Chan, Wilson Wai San Tam, Yiong Huak Chan
AIM: To examine the effectiveness of 'Home-but not Alone', a postnatal psychoeducational programme delivered via a mobile-health application for parents during the early postpartum period to improve parenting outcomes. BACKGROUND: The early postpartum period is often a challenging but crucial period for new parents. Supportive educational programmes delivered via mobile-health applications are needed to improve parenting outcomes. DESIGN: A randomized controlled two-group pre-test and post-test design was adopted...
March 9, 2017: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/28273912/emotional-anticipation-after-delivery-a-longitudinal-neuroimaging-study-of-the-postpartum-period
#18
Malin Gingnell, Simone Toffoletto, Johan Wikström, Jonas Engman, Elin Bannbers, Erika Comasco, Inger Sundström-Poromaa
Neuroimaging research has begun to unveil the mechanisms behind emotion processing during the postpartum period, which, in turn, may be of relevance for the development of postpartum depression. The present study sought to longitudinally investigate the neural correlates of emotion anticipation during the postpartum period in healthy women. Functional magnetic resonance imaging was employed to measure the blood oxygen level-dependent signal in the brain in response to anticipation of negative emotional stimuli and during processing of images with positive or negative valence...
December 2017: Scientific Reports
https://www.readbyqxmd.com/read/28260619/improving-discrimination-in-antepartum-depression-screening-using-the-edinburgh-postnatal-depression-scale
#19
Kartik K Venkatesh, Anjali J Kaimal, Victor M Castro, Roy H Perlis
BACKGROUND: Universal screening of pregnant women for postpartum depression has recently been recommended; however, optimal application of depression screening tools in stratifying risk has not been defined. The current study examines new approaches to improve the ability of the Edinburgh Postnatal Depression Scale (EPDS) to stratify risk for postpartum depression, including alternate cut points, use of a continuous measure, and incorporation of other putative risk factors. METHODS: An observational cohort study of 4939 women screened both antepartum and postpartum with a negative EPDS screen antepartum(i...
February 24, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28258970/cohort-study-of-the-depression-anxiety-and-anhedonia-components-of-the-edinburgh-postnatal-depression-scale-after-delivery
#20
Vincenzo Zanardo, Lara Giliberti, Francesca Volpe, Matteo Parotto, Federico de Luca, Gianluca Straface
OBJECTIVE: To investigate the applicability of the Edinburgh Postnatal Depression Scale (EPDS) for identifying depressive symptoms following vaginal or cesarean delivery. METHODS: The present observational study included consecutive Italian-speaking women who underwent vaginal or cesarean deliveries of uncomplicated singleton pregnancies at term at Policlinico Abano Terme, Abano Terme, Italy, between February 1, 2014, and May 31, 2015, who completed the EPDS 2 days after delivery...
March 4, 2017: International Journal of Gynaecology and Obstetrics
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