keyword
https://read.qxmd.com/read/38520314/echocardiographic-haemodynamic-monitoring-in-the-context-of-heartmate-3%C3%A2-therapy-a-systematic-review
#1
JOURNAL ARTICLE
Linus Ohlsson, Joanna-Maria Papageorgiou, Tino Ebbers, Meriam Åström Aneq, Éva Tamás, Hans Granfeldt
AIMS: While echocardiography remains essential within haemodynamic monitoring of durable mechanical circulatory support, previous echocardiographic guidelines are missing scientific evidence for the novel HeartMate 3™ (HM3) system. Accordingly, this review aims to summarize available echocardiographic evidence including HM3. METHODS AND RESULTS: This systematic review adhered to the PRISMA 2020 guidelines. Searches were conducted during August 2023 across PubMed, Embase, and Google Scholar using specific echocardiographic terms combined with system identifiers...
March 23, 2024: ESC Heart Failure
https://read.qxmd.com/read/38517620/a-computational-investigation-of-the-effects-of-temporal-synchronization-of-left-ventricular-assist-device-speed-modulation-with-the-cardiac-cycle-on-intraventricular-hemodynamics
#2
JOURNAL ARTICLE
Angela Straccia, Fanette Chassagne, Michael C Barbour, Jennifer Beckman, Song Li, Claudius Mahr, Alberto Aliseda
Patients with advanced heart failure are implanted with a left ventricular assist device (LVAD) as a bridge-to-transplantation or destination therapy. Despite advances in pump design, the risk of stroke remains high. LVAD implantation significantly alters intraventricular hemodynamics, where regions of stagnation or elevated shear stresses promote thrombus formation. Third generation pumps incorporate a pulsatility mode that modulates rotational speed of the pump to enhance in-pump washout. We investigated how the timing of the pulsatility mode with the cardiac cycle affects intraventricular hemodynamic factors linked to thrombus formation...
March 22, 2024: Annals of Biomedical Engineering
https://read.qxmd.com/read/38488713/preliminary-report-of-extracorporeal-blood-purification-therapy-in-patients-receiving-lvad-cytosorb-or-jafron-ha330
#3
RANDOMIZED CONTROLLED TRIAL
Zhuldyz Nurmykhametova, Timur Lesbekov, Rymbay Kaliyev, Bolat Bekishev, Nilufar Jabayeva, Svetlana Novikova, Linar Faizov, Ivan Vakhrushev, Yuriy Pya
BACKGROUND: Left ventricular assist device (LVAD) candidates are at increased risk of immune dysregulation and infectious complications. To attenuate the elevated proinflammatory cytokine levels and associated adverse clinical outcomes, it has been postulated that extracorporeal blood purification could improve the overall survival rate and morbidity of patients undergoing LVAD implantation. METHODS: We retrospectively reviewed prospectively collected data of 15 patients who underwent LVAD implantation at our center between January 2021 and March 2022...
March 2024: Journal of Extra-corporeal Technology
https://read.qxmd.com/read/38459775/heartmate-3-implantation-with-an-emphasis-on-the-biventricular-configuration
#4
JOURNAL ARTICLE
Silvana F Marasco, Janelle McLean, Christina E Kure, Julia Rix, Tanieka Lake, Ashlee Linton, James Farag, Michael Z L Zhu, Atsuo Doi, Peter J Bergin, Angeline S Leet, Andrew J Taylor, James L Hare, Hitesh C Patel, David Kaye, David C McGiffin
OBJECTIVES: Right ventricular failure following implantation of a durable left ventricular assist device (LVAD) is a major driver of mortality. Reported survival following biventricular (BiVAD) or total artificial heart (TAH) implantation remains substantially inferior to LVAD alone. We report our outcomes with LVAD and BiVAD HeartMate 3 (HM3). METHODS: Consecutive patients undergoing implantation of an HM3 LVAD between November 2014 and December 2021, at The Alfred, Australia were included in the study...
March 8, 2024: Artificial Organs
https://read.qxmd.com/read/38459758/multicenter-evaluation-of-left-ventricular-assist-device-implantation-with-or-without-ecmo-bridge-in-cardiogenic-shock
#5
JOURNAL ARTICLE
James W Schurr, Lara Ambrosi, Jillian Fitzgerald, Christian Bermudez, Michael V Genuardi, Mark Brahier, Tonya Elliot, Kevin McGowan, Akram Zaaqoq, Sonjoy Laskar, Stuart M Pope, Michael M Givertz, Hari Mallidi, Katelyn W Sylvester, Frank C Seifert, Allison J McLarty
BACKGROUND: The efficacy of extracorporeal membrane oxygenation (ECMO) as a bridge to left ventricular assist device (LVAD) remains unclear, and recipients of the more contemporary HeartMate 3 (HM3) LVAD are not well represented in previous studies. We therefore undertook a multicenter, retrospective study of this population. METHODS AND RESULTS: INTERMACS 1 LVAD recipients from five U.S. centers were included. In-hospital and one-year outcomes were recorded. The primary outcome was the overall mortality hazard comparing ECMO versus non-ECMO patients by propensity-weighted survival analysis...
March 8, 2024: Artificial Organs
https://read.qxmd.com/read/38452886/reversibility-of-precapillary-pulmonary-hypertension-and-outcomes-after-heart-transplantation-bridged-with-left-ventricular-assist-devices-insight-from-the-unos
#6
JOURNAL ARTICLE
Hilmi Alnsasra, Radha Kanneganti Perue, Fouad Khalil, Ohad Regev, Sudhir S Kushwaha, Alexandros Briasoulis, Rabea Asleh
BACKGROUND: In light of the updated lowered threshold for diagnosing pulmonary hypertension (PH), the reversibility of precapillary PH with left ventricular assist device (LVAD) and the associated post heart transplantation (HT) outcomes remain unclear. AIM AND METHODS: Using data from the United Network for Organ Sharing database, we aimed to investigate predictors of persistent precapillary PH in HT recipients bridged with LVAD, and examine the interrelated post-HT survival, using the updated pulmonary vascular resistance (PVR) cutoff of >2 WU for precapillary PH...
March 5, 2024: Journal of Thoracic and Cardiovascular Surgery
https://read.qxmd.com/read/38446866/the-longest-living-patient-supported-with-left-ventricular-assist-device-14-years
#7
JOURNAL ARTICLE
Ann Hallberg Kristensen, Peter Svenarud, Lars H Lund, Emil Najjar
Left ventricular assist devices (LVADs) improve survival and reduce symptoms in patients with advanced heart failure; however, the longer-term durability of LVADs remains uncertain especially with older-generation devices. In this case report, we describe the clinical course of a patient who has been successfully treated with the same HeartMate II LVAD for 14 years, the longest published and still ongoing LVAD support with the same originally implanted device.
March 6, 2024: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://read.qxmd.com/read/38400624/absorbable-antibiotic-beads-for-treatment-of-lvad-driveline-infections
#8
Ishaq Wadiwala, Pankaj Garg, Emad Alamouti-Fard, Kevin Landolfo, Basar Sareyyupoglu, Magdy El-Sayed Ahmed, Samuel Jacob, Si Pham
BACKGOUND: Infections of the left ventricular assist device (LVAD) driveline are a dreaded complication that results in high mortality and morbidity. METHOD: We retrospectively reviewed five consecutive patients with severe continuous-flow LVAD (HVAD, Heartmate 2, and Heartmate 3) driveline infection. These infections, which developed on an average of 960.4 ± 843.9 days after LVAD placement, were refractory to systemic antibiotics and local wound care...
February 23, 2024: Artificial Organs
https://read.qxmd.com/read/38396198/successful-management-of-heartmate-3-in-a-patient-with-arrhythmogenic-right-ventricular-cardiomyopathy
#9
JOURNAL ARTICLE
Makiko Nakamura, Teruhiko Imamura, Yuki Hida, Toshihide Izumida, Masaki Nakagaito, Saori Nagura, Toshio Doi, Kazuaki Fukahara, Koichiro Kinugawa
The management of right heart failure during durable left ventricular assist device (LVAD) support remains an unsolved issue so far. We had a 44-year-old male patient who was diagnosed with arrhythmogenic right ventricular cardiomyopathy and received HeartMate 3 LVAD (Abbott, USA) implantation as a bridge-to-transplant indication. The pump speed was adjusted as low as 4500 rpm to avoid the left ventricular narrowing and interventricular septal leftward shift. Riociguat was administered to decrease the afterload of the right ventricle and increase the preload of the left ventricle, in addition to the combination of neurohormonal blockers...
February 24, 2024: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://read.qxmd.com/read/38380771/intracorporeal-lvad-implantation-in-pediatric-patients-a-single-center-10%C3%A2-years-experience
#10
Irene Cao, Enrico G Italiano, Francesco Bertelli, Raffaella Motta, Biagio Castaldi, Valeria Pergola, Alvise Guariento, Fabio Scattolin, Giovanni Di Salvo, Vladimiro Vida, Massimo A Padalino
BACKGROUND: Mechanical cardiac support is currently an effective strategy to reduce morbidity and mortality in pediatric patients. However, solid evidence regarding the feasibility of intracorporeal devices in children still needs to be provided. We report our 10-year experience with intracorporeal left ventricular assist devices (LVAD) in children. MATERIALS AND METHODS: We included all patients undergoing intracorporeal, continuous-flow LVAD implantation between 2012 and 2022...
February 21, 2024: Artificial Organs
https://read.qxmd.com/read/38375350/percutaneous-endovascular-stenting-to-treat-left-ventricular-assist-device-outflow-graft-stenosis
#11
Aaron Litvak, Kshitij Desai, Craig Narins, Doran Mix
A 72-year-old woman presented with acute symptoms of congestive heart failure exacerbation and cardiogenic shock secondary to flow alarms in her HeartMate II left ventricular assist device (LVAD) placed in 2013. Her rapid deterioration required venoarterial extracorporeal membrane oxygenation placement with subsequent cardiac catheterization. A computed tomography scan corroborated 90% stenosis of the LVAD outflow graft with mural thrombus causing cardiogenic shock. A multidisciplinary team proceeded with endovascular treatment of the LVAD outflow obstruction via realignment with percutaneous angioplasty and placement of covered stent grafts...
April 2024: Journal of Vascular Surgery Cases and Innovative Techniques
https://read.qxmd.com/read/38373176/hemodynamic-optimization-by-invasive-ramp-test-in-patients-supported-with-heartmate-3-left-ventricular-assist-device
#12
JOURNAL ARTICLE
Gal Rubinstein, Cathrine M Moeller, Dor Lotan, Sharon Slomovich, Andrea Fernandez-Valledor, Daniel Oren, Kyung T Oh, Justin A Fried, Kevin J Clerkin, Jayant K Raikhelkar, Veli K Topkara, Yuji Kaku, Koji Takeda, Yoshifumi Naka, Daniel Burkhoff, Farhana Latif, David Majure, Paolo C Colombo, Melana Yuzefpolskaya, Gabriel T Sayer, Nir Uriel
In patients supported by the HeartMate 3 left ventricular assist device (HM3 LVAD), pump speed adjustments may improve hemodynamics. We investigated the hemodynamic implications of speed adjustments in HM3 recipients undergoing hemodynamic ramp tests. Clinically stable HM3 recipients who underwent routine invasive hemodynamic ramp tests between 2015 and 2022 at our center were included. Filling pressure optimization, defined as central venous pressure (CVP) <12 mm Hg and pulmonary capillary wedge pressure (PCWP) <18 mm Hg, was assessed at baseline and final pump speeds...
February 20, 2024: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://read.qxmd.com/read/38373165/durable-right-ventricular-assist-device-heartmate-3-implant-to-the-right-atrium-for-right-ventricular-failure-after-lvad-implant
#13
JOURNAL ARTICLE
Chamogeorgakis Themistokles, Antigoni Koliopoulou, Evangelos Leontiadis, Angeliki Gkouziouta, Michael J Bonios
No abstract text is available yet for this article.
February 19, 2024: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://read.qxmd.com/read/38367698/ventricular-assist-device-using-a-thoracotomybased-implant-technique-multi-center-heartmate-3-swift-study
#14
JOURNAL ARTICLE
Igor Gosev, Duc Thinh Pham, John Y Um, Anelechi C Anyanwu, Akinobu Itoh, Kunal Kotkar, Koji Takeda, Yoshifumi Naka, Matthias Peltz, Scott C Silvestry, Gregory Couper, Marzia Leacche, Vivek Rao, Benjamin Sun, Ryan J Tedford, Nahush Mokadam, Robert McNutt, Daniel Crandall, Mandeep R Mehra, Christopher T Salerno
OBJECTIVES: The HeartMate 3 (HM3) left ventricular assist device (LVAD) provides substantial improvement in long-term morbidity and mortality in advanced heart failure patients. The SWIFT study compares thoracotomy-based implantation clinical outcomes with standard median sternotomy. METHODS: We conducted a prospective, multicenter, single-arm study in patients eligible for HM3 implantation with thoracotomy-based surgical technique (bilateral thoracotomy or partial upper sternotomy with left thoracotomy)...
February 15, 2024: Journal of Thoracic and Cardiovascular Surgery
https://read.qxmd.com/read/38360679/surgical-outcomes-of-centrifugal-continuous-flow-implantable-left-ventricular-assist-devices-heartmate-3-versus-heartware-ventricular-assist-device
#15
JOURNAL ARTICLE
Kinam Shin, Won Chul Cho, Nara Shin, Hong Rae Kim, Min-Seok Kim, Cheol Hyun Chung, Sung-Ho Jung
BACKGROUND: Left ventricular assist devices (LVADs) are widely employed as a therapeutic option for end-stage heart failure. We evaluated the outcomes associated with centrifugal- flow LVAD implantation, comparing 2 device models: the Heartmate 3 (HM3) and the Heartware Ventricular Assist Device (HVAD). METHODS: Data were collected from patients who underwent LVAD implantation between June 1, 2015 and December 31, 2022. We analyzed overall survival, first rehospitalization, and early, late, and LVAD-related complications...
February 16, 2024: Journal of chest surgery
https://read.qxmd.com/read/38313380/emergent-decommissioning-of-heartmate-3-for-life-threatening-hemorrhage
#16
Reginald E Du, Ryan S Bedi, W Charles Sternbergh, Aditya Bansal
Left ventricular assist devices are known for the treatment of heart failure. We present a patient who underwent emergent decommissioning of his left ventricular assist device after experiencing life-threatening hemorrhage. In this case, the patient's outflow graft was avulsed from his left subclavian artery. We used a covered stent to first exclude the outflow graft and an Amplatzer II plug (Abbott Cardiovascular) to then occlude the inflow cannula. Accessing the inflow cannula of the left ventricular assist device was challenging...
April 2024: Journal of Vascular Surgery Cases and Innovative Techniques
https://read.qxmd.com/read/38272130/left-ventricular-assist-device-in-the-presence-of-subcutaneous-implantable-cardioverter-defibrillator-data-from-a-multicenter-experience
#17
JOURNAL ARTICLE
Federico Migliore, Marco Schiavone, Raimondo Pittorru, Giovanni B Forleo, Manuel De Lazzari, Gianfranco Mitacchione, Mauro Biffi, Simone Gulletta, Jurgen Kuschyk, Pietro Bernardo Dall'Aglio, Giovanni Rovaris, Roland Tilz, Florinda Rosaria Mastro, Sabino Iliceto, Claudio Tondo, Luigi Di Biase, Alessio Gasperetti, Vincenzo Tarzia, Gino Gerosa
BACKGROUND: Left ventricular assist devices (LVADs) are an increasingly used strategy for the management of patients with advanced heart failure (HF).Subcutaneous implantable cardioverter defibrillator (S-ICD) might be a viable alternative to conventional ICDs with a lower risk of short- and long-term of device-related complications and infections.The aim of this multicenter study was to evaluate the outcomes and management of S-ICD recipients who underwent LVAD implantation. METHODS: The study population included patients with a preexisting S-ICD who underwent LVAD implantation for advanced HF despite optimal medical therapy...
January 23, 2024: International Journal of Cardiology
https://read.qxmd.com/read/38270519/lightning-strike-induced-damage-leading-to-urgent-left-ventricular-assist-device-exchange
#18
Ali Saad Merzah, Eleftherios Beltsios, Bastian Schmack, Guenes Dogan, Arjang Ruhparwar, Jan D Schmitto, Jasmin S Hanke
No abstract text is available yet for this article.
January 25, 2024: Artificial Organs
https://read.qxmd.com/read/38250571/conservative-management-of-lvad-associated-ventricular-pseudoaneurysm
#19
Marvin Kajy, Connor C Kerndt, Paul C Weber, Marzia Leacche, Renzo Y Loyaga Rendon
Left ventricular assist devices (LVAD) are surgically implanted mechanical support devices utilized with increasing frequency as a bridge to myocardial recovery, destination therapy, and heart transplantation. While the use of such devices in patients with advanced heart failure has shown significant survival benefits and improved quality of life, they bear their own risks and complications.1 Bleeding, infection, pump thrombosis, and stroke are just some of the serious complications associated with LVADs.2 LVAD-associated pseudoaneurysms are rare, with prior reports of occurrence at the left ventricular apex and at the anastomosis site of the outflow graft to the ascending aorta...
2024: Methodist DeBakey Cardiovascular Journal
https://read.qxmd.com/read/38249117/a-low-dose-thrombolytic-infusion-protocol-for-safe-and-successful-treatment-of-left-ventricular-assist-device-thrombosis-a-case-series
#20
Ramakrishna Gorantla, Aiham Albaeni, Muhammad W Choudhry, Vincent Conti, Scott Lick, Wissam I Khalife, Khaled Chatila
BACKGROUND: Pump thrombosis is a serious complication of continuous-flow left ventricular assist device (CF-LVAD) therapy. In this study, we aim to report a novel protocol of an intermittent, low-dose, and slow infusion of tissue plasminogen activator (alteplase). CASE SUMMARY: We treated seven LVAD pump thrombosis events (HeartMate® II and HeartWare) in four patients with a median age of 52 years (31-63), and all were female. The protocol was applied from January 2015 to December 2018, and it consisted of an intermittent, low-dose, and slow infusion of systemic thrombolytic therapy in the intensive care unit...
January 2024: European Heart Journal. Case Reports
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