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https://www.readbyqxmd.com/read/29045980/-anti-neutrophil-cytoplasmic-antibodies-associated-vasculitis-with-lung-hemorrhage-in-the-patient-on-maintenance-haemodialysis-a-case-report
#1
J X Ding, M Wang
Anti-neutrophil cytoplasmic antibodies (ANCA)-associated vasculitis (AAV) is usually a multisystem disorder, and pulmonary renal syndrome is a common presentation. Patients with AAV are less likely to experience relapse when they progress to end-stage renal disease (ESRD). We report a rare case of diffuse alveolar hemorrhage (DAH) in relapsing AAV after eight years of haemodialysis. A 58-year-old woman was admitted to our hospital with the chief complaints of dyspnea and hemoptysis accompanied by anemia, fever, fatigue, and weight loss...
October 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/29044634/rituximab-for-the-treatment-of-type-b-insulin-resistance-syndrome-a-case-report-and-review-of-the-literature
#2
Ken Iseri, Masayuki Iyoda, Yasuto Shikida, Takako Inokuchi, Tomoki Morikawa, Noriko Hara, Tsutomu Hirano, Takanori Shibata
BACKGROUND: Type B insulin resistance syndrome is a rare disease characterized by refractory transient hyperglycaemia and severe insulin resistance associated with circulating anti-insulin receptor antibodies. A standardized treatment regimen for type B insulin resistance syndrome has yet to be established. CASE REPORT: We report the case of a 64-year-old man undergoing haemodialysis for antineutrophil cytoplasmic antibody-associated vasculitis and diabetic nephropathy, who developed rapid onset of hyperglycaemia (glycated albumin 52...
October 16, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/29038191/obstructive-uropathy-as-initial-presentation-of-genitourinary-tuberculosis-and-masquerading-as-a-postsurgical-complication
#3
Grace Igiraneza, Theobald Hategekimana, Olivier M Manzi, Onyema Ogbuagu
A 46-year-old woman who had a recent total abdominal hysterectomy presented with a 1 month history of lower abdominal pain, 1 week of nausea and vomiting as well as decreased urinary output preceded by a year of significant unintentional weight loss. On renal imaging, she was found to have bilateral hydronephrosis and hydroureters in the setting of bilateral distal ureteric obstruction complicated with acute kidney injury and severe hyperkalaemia requiring haemodialysis. The initial concern was for ureteric injury, a known complication of abdominal hysterectomy procedures, however, a urological intervention, performed 9 months later to relieve the ureteric obstruction, revealed purulent material within the left ureter that was smear positive for acid fast bacilli...
October 15, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29036505/increased-mortality-in-haemodialysis-patients-administered-high-doses-of-erythropoiesis-stimulating-agents-a-propensity-score-matched-analysis
#4
Rafael Pérez-García, Javier Varas, Alejandro Cives, Alejandro Martín-Malo, Pedro Aljama, Rosa Ramos, Julio Pascual, Stefano Stuard, Bernard Canaud, José Ignacio Merello
Background: Erythropoiesis-stimulating agents (ESAs) are widely used to treat anaemia in patients with chronic kidney disease. The issue of ESA safety has been raised in multiple studies, with correlates derived for elevated cancer incidence and mortality. Whether these associations are related to ESA dose or the typology of the patient remains obscure. Methods: A multicentre, observational retrospective propensity score-matched study was designed to analyse the effects of weekly ESA dose in 1679 incident haemodialysis (HD) patients...
September 28, 2017: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/29029967/-10-years-of-external-quality-assurance-in-dialysis-in-germany-results-and-future-prospects
#5
Dorothea Büchtemann, Stefan Meinhold, Peter Follert
BACKGROUND: In 2006, the Federal Joint Committee introduced a quality assurance programme for ambulatory dialysis treatment in Germany. Regarding the impact of chronic dialysis treatment on the quality of life of patients and on health care costs, quality assurance in dialysis is considered highly relevant. The directive on Quality Assurance in Dialysis (QSD-RL) established an external quality assurance programme based on the assessment of certain quality parameters combined with an internal quality management system based on benchmarking parameters in all dialysis practices and centres...
October 10, 2017: Zeitschrift Für Evidenz, Fortbildung und Qualität Im Gesundheitswesen
https://www.readbyqxmd.com/read/29028929/peripheral-i-v-analysis-piva-of-venous-waveforms-for-volume-assessment-in-patients-undergoing-haemodialysis
#6
K M Hocking, B D Alvis, F Baudenbacher, R Boyer, C M Brophy, I Beer, S Eagle
Background: The assessment of intravascular volume status remains a challenge for clinicians. Peripheral i.v. analysis (PIVA) is a method for analysing the peripheral venous waveform that has been used to monitor volume status. We present a proof-of-concept study for evaluating the efficacy of PIVA in detecting changes in fluid volume. Methods: We enrolled 37 hospitalized patients undergoing haemodialysis (HD) as a controlled model for intravascular volume loss...
September 27, 2017: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29028161/effect-of-haemodialysis-and-residual-renal-function-on-serum-levels-of-galectin-3-b-type-natriuretic-peptides-and-cardiac-troponin-t
#7
Matthew A Roberts, Piyush M Srivastava, David L Hare, Francesco L Ierino
AIM: Levels of plasma markers of myocardial fibrosis (galectin-3), stretch (B-type natriuretic peptide (BNP)) and injury (troponin T (TnT)) may be affected by haemodialysis and residual renal function (RRF) in addition to cardiac pathology. We aimed to determine the association of RRF, urine output and haemodialysis itself on clinically important cardiac biomarkers in haemodialysis patients. METHODS: Adult haemodialysis patients underwent venesection pre- and post- haemodialysis followed by echocardiography and inter-dialytic urine collection to calculate RRF (mL/minute/1...
October 13, 2017: Nephrology
https://www.readbyqxmd.com/read/29026875/ethylene-glycol-poisoning-should-not-contraindicate-liver-donation
#8
Alisha Burman, Christopher J E Watson, Vasilis Kosmoliaptsis
As the number of patients waiting to receive transplants increases, there is a need to explore all possible donation opportunities. In this case report, we describe the transplantation of a liver from a donor who died after ethylene glycol poisoning into a woman with alcoholic liver disease with cirrhosis and associated ascites. Donor management, including ethanol, fomepizol and haemodialysis, hastened clearance of ethylene glycol from the circulation, and after liver transplantation, the recipient exhibited no adverse effects suggestive of ethylene glycol toxicity, although recipient hepatic artery dissection and thrombosis necessitated retransplantation...
October 2017: Transplantation Direct
https://www.readbyqxmd.com/read/29025150/collection-and-determinants-of-patient-reported-outcome-measures-in-haemodialysis-patients-in-scotland
#9
Ailish Nimmo, Samira Bell, Carol Brunton, Jacqueline Campbell, Arthur Doyle, Bruce MacKinnon, Robert K Peel, Susan Robertson, Ilona Shilliday, Elaine Spalding, Jamie P Traynor, Wendy Metcalfe
Background: Patient reported outcome measures (PROMs) can evaluate the quality of health in patients with established renal failure. There is limited experience of their use within national renal registries. Aim: To describe the Scottish Renal Registry's (SRR) experience of collecting PROMS in the haemodialysis population and correlate PROMS to demographic and clinical parameters. Design: Retrospective observational cross-sectional study. Methods: Haemodialysis patients in Scotland were invited to complete the KDQOL™-36 questionnaire on the day of the annual SRR census in 2015 and 2016...
September 18, 2017: QJM: Monthly Journal of the Association of Physicians
https://www.readbyqxmd.com/read/28992899/tailored-online-cognitive-behavioural-therapy-with-or-without-therapist-support-calls-to-target-psychological-distress-in-adults-receiving-haemodialysis-a-feasibility-randomised-controlled-trial
#10
Joanna L Hudson, Rona Moss-Morris, Sam Norton, Federica Picariello, David Game, Amy Carroll, Jonathan Spencer, Paul McCrone, Matthew Hotopf, Lucy Yardley, Joseph Chilcot
BACKGROUND: Psychological distress is prevalent in haemodialysis (HD) patients yet access to psychotherapy remains limited. This study assessed the feasibility and acceptability of online cognitive-behavioural therapy (CBT) tailored for HD patients, with or without therapist support, for managing psychological distress. METHODS: This feasibility randomised controlled trial recruited patients from a UK HD centre. Following psychological distress screens, patients with mild-moderate psychological distress (Patient Health Questionnaire PHQ-9; score: 5-19 and/or Generalised Anxiety Disorder; GAD-7 score: 5-14) who met remaining inclusion criteria were approached for consent...
November 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/28992335/how-to-set-the-stage-for-a-full-fledged-clinical-trial-testing-incremental-haemodialysis
#11
Francesco Gaetano Casino, Carlo Basile
Most people who make the transition to maintenance haemodialysis (HD) therapy are treated with a fixed dose of thrice-weekly HD (3HD/week) regimen without consideration of their residual kidney function (RKF). The RKF provides an effective and naturally continuous clearance of both small and middle molecules, plays a major role in metabolic homeostasis, nutritional status and cardiovascular health, and aids in fluid management. The RKF is associated with better patient survival and greater health-related quality of life...
July 21, 2017: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/28992224/modulation-of-leucocytic-angiotensin-converting-enzymes-expression-in-patients-maintained-on-high-permeable-haemodialysis
#12
Bogusz Trojanowicz, Christof Ulrich, Roman Fiedler, Peter Martus, Markus Storr, Torsten Boehler, Kristin Werner, Michael Hulko, Daniel Zickler, Kevin Willy, Ralf Schindler, Matthias Girndt
Background: High mortality of haemodialysis patients is associated with systemic chronic inflammation and overactivation of the renin-angiotensin system (RAS). Insufficient elimination of pro-inflammatory immune mediators, especially in the molecular weight range of 15-45 kDa, may be one of the reasons for this. Employment of haemodialysis membranes with increased permeability was shown to ameliorate the inflammatory response and might modulate the effects of local RAS. In this study, we tested the impact of high cut-off (HCO), medium cut-off (MCO) and high-flux (HF) dialysis on leucocytic transcripts of angiotensin-converting enzymes (ACE and ACE2)...
July 19, 2017: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/28992140/inflammation-induces-osteoclast-differentiation-from-peripheral-mononuclear-cells-in-chronic-kidney-disease-patients-crosstalk-between-the-immune-and-bone-systems
#13
Cesira Cafiero, Margherita Gigante, Giacomina Brunetti, Simona Simone, Nada Chaoul, Angela Oranger, Elena Ranieri, Silvia Colucci, Giovanni B Pertosa, Maria Grano, Loreto Gesualdo
Background: Inflammation and immune system alterations contribute to bone damage in many pathologies by inducing the differentiation of osteoclasts (OCs), the bone resorbing cells. This link is largely unexplored in chronic kidney disease (CKD) and haemodialysis (HD) patients, in which reduced renal function is accompanied by an increased inflammatory state and skeletal abnormality. Methods: We used ex vivo culture experiments to investigate the osteoclastogenic potential of peripheral blood mononuclear cells (PBMCs) of CKD and HD patients, focusing on immune cell subsets and inflammatory cytokines such as LIGHT and receptor activator of nuclear factor κB ligand (RANKL)...
July 21, 2017: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/28992120/relationships-between-iron-dose-hospitalizations-and-mortality-in-incident-haemodialysis-patients-a-propensity-score-matched-approach
#14
Javier Varas, Rosa Ramos, Pedro Aljama, Rafael Pérez-García, Francesc Moreso, Miguel Pinedo, José Ignacio Merello, Stefano Stuard, Bernard Canaud, Alejandro Martín-Malo
Background: Intravenous iron management is common in the haemodialysis population. However, the safest dosing strategy remains uncertain, in terms of the risk of hospitalization and mortality. We aimed to determine the effects of cumulative monthly iron doses on mortality and hospitalization. Methods: This multicentre observational retrospective propensity-matched score study included 1679 incident haemodialysis patients. We measured baseline demographic variables, haemodialysis clinical parameters and laboratory analytical values...
July 13, 2017: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/28991029/successful-treatment-with-tenofovir-alafenamide-of-a-hiv-hepatitis-b-virus-coinfected-patient-with-hiv-and-hepatitis-b-virus-drug-resistance-end-stage-renal-disease-on-haemodialysis
#15
Alessandra Tartaglia, Sergio Maria Ferrara, Salvatore Sica, Teresa Santantonio
No abstract text is available yet for this article.
October 23, 2017: AIDS
https://www.readbyqxmd.com/read/28989570/eye-and-foot-checks-in-patients-with-diabetes-on-haemodialysis-are-they-done-and-who-does-them
#16
Nadira Bibi Mothojakan, Shazia Hussain, Kieran McCafferty, Mohammed Magdi Yaqoob, Tahseen Ahmad Chowdhury
AIM: To determine if retinal and foot checks are carried out on patients with diabetes receiving haemodialysis. METHODS: Eighty-four patients with diabetes receiving haemodialysis were asked if they recalled having eye and foot screening in the last year, and if so, by whom was the check done. RESULTS: Seventy-seven (91.7%) patients recalled having an eye check in the preceding 12 mo. Of these, 52 (67.5%) did so in an ophthalmology clinic, 17 (22%) in retinal screening, three (3...
September 15, 2017: World Journal of Diabetes
https://www.readbyqxmd.com/read/28985589/screening-for-psychological-distress-using-the-patient-health-questionnaire-anxiety-and-depression-scale-phq-ads-initial-validation-of-structural-validity-in-dialysis-patients
#17
Joseph Chilcot, Joanna L Hudson, Rona Moss-Morris, Amy Carroll, David Game, Anna Simpson, Matthew Hotopf
OBJECTIVE: To validate the factor structure of the Patient Health Questionnaire Anxiety and Depression Scale (PHQ-ADS)- which is a composite measure of depression and anxiety using the Patient Health Questionnaire-9 and Generalised Anxiety Disorder Scale (GAD-7), in a sample of haemodialysis patients. METHOD: Screening data (n=182) used to select entry into a feasibility study of an online cognitive-behavioural therapy intervention for distress in dialysis patients were analysed here...
September 28, 2017: General Hospital Psychiatry
https://www.readbyqxmd.com/read/28979785/estimated-dietary-sodium-intake-in-haemodialysis-patients-using-food-frequency-questionnaires
#18
Anastasia Gkza, Andrew Davenport
BACKGROUND: In clinical practice, dietary sodium assessment requires reliable and rapid screening tools. We wished to evaluate the usefulness of food frequency questionnaires (FFQ) in estimating dietary sodium intakes in haemodialysis patients. METHODS: We used the Derby Salt Questionnaire (DSQ), and Scored Sodium Questionnaire (SSQ) to estimate sodium intake. Body composition was determined by bioimpedance. RESULTS: In total, 139 haemodialysis patients (95 men) completed the FFQs, with mean ± standard deviation age 67 ± 15 years...
October 2017: Clinical Kidney Journal
https://www.readbyqxmd.com/read/28979783/obesity-and-listing-for-renal-transplantation-weighing-the-evidence-for-a-growing-problem
#19
Mohammed Hossain, Alexander Woywodt, Titus Augustine, Videha Sharma
A 56-year-old female patient was referred to the transplant assessment clinic in July 2016. She started haemodialysis in 2012 for renal failure due to urinary tract infections. She is doing very well on dialysis and has an excellent exercise tolerance without shortness of breath or angina. She has had no infections since starting dialysis and no other comorbidity, except well-controlled hypertension and hyperparathyroidism requiring treatment with cinacalcet. Clinical examination is essentially normal except for truncal obesity with height 167 cm and weight 121 kg, giving her a body mass index of 43...
October 2017: Clinical Kidney Journal
https://www.readbyqxmd.com/read/28979637/seroprevalence-of-human-immunodeficiency-virus-hepatitis-b-and-c-viruses-among-haemodialysis-patients-in-two-newly-opened-centres-in-cameroon
#20
Henry Namme Luma, Marie Patrice Halle, Servais Albert Fiacre Bagnaka Eloumou, Fondong Azingala, Felicite Kamdem, Olivier Donfack-Sontsa, Gloria Ashuntantang
INTRODUCTION: Haemodialysis (HD) patients are potentially susceptible to infection with blood borne viral agents especially; Human Immunodeficiency Virus (HIV), hepatitis B (HBV) and hepatitis C Viruses (HCV), compared to the general population. We described their epidemiology in two newly created haemodialysis units in Cameroon: the Buea and Bamenda haemodialysis centres. METHODS: A cross sectional study: included were patients who had spent at least three months in haemodialysis...
2017: Pan African Medical Journal
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