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https://www.readbyqxmd.com/read/28548651/foetal-haemoglobin-blood-transfusion-and-retinopathy-of-prematurity-in-very-preterm-infants-a-pilot-prospective-cohort-study
#1
C J Stutchfield, A Jain, D Odd, C Williams, R Markham
PurposeTo identify if there is an association between foetal haemoglobin (HbF) concentration and retinopathy of prematurity (ROP) in very preterm infants.Patients and methodsProspective cohort study. Infants born <32 weeks' gestational age or <1501 g in two tertiary neonatal units between January 2012 and May 2013 (n=42) were enrolled. HbF and adult haemoglobin (HbA) concentrations were measured using high-pressure liquid chromatography from blood samples sent as part of routine neonatal care once routinely requested laboratory tests had been performed...
May 26, 2017: Eye
https://www.readbyqxmd.com/read/28547531/neonatal-hyperoxia-perturbs-neuronal-development-in-the-cerebellum
#2
Till Scheuer, Yuliya Sharkovska, Victor Tarabykin, Katharina Marggraf, Vivien Brockmöller, Christoph Bührer, Stefanie Endesfelder, Thomas Schmitz
Impaired postnatal brain development of preterm infants often results in neurological deficits. Besides pathologies of the forebrain, maldeveolopment of the cerebellum is increasingly recognized to contribute to psychomotor impairments of many former preterm infants. However, causes are poorly defined. We used a hyperoxia model to define neonatal damage in cerebellar granule cell precursors (GCPs) and in Purkinje cells (PCs) known to be essential for interaction with GCPs during development. We exposed newborn rats to 24 h 80% O2 from age P6 to P7 to identify postnatal and long-term damage in cerebellar GCPs at age P7 after hyperoxia and also after recovery in room air thereafter until P11 and P30...
May 25, 2017: Molecular Neurobiology
https://www.readbyqxmd.com/read/28546662/pregnancy-outcome-in-patients-with-solitary-kidney
#3
Vineet V Mishra, Kavita M Mistry, Sakshi S Nanda, Sumesh Choudhary, Rohina Aggarwal, Khushali Gandhi
BACKGROUND: Solitary kidney may be congenital or as a result of nephrectomy. There is a lot of literature available on quality of life in these patients, but there is limited data on pregnancy outcome. OBJECTIVES: To study pregnancy outcome in patients with solitary kidney either congenital or due to nephrectomy. MATERIALS AND METHODS: Study Design This is a retrospective observational study conducted at tertiary health center in Ahmedabad, from 2011 to 2014...
June 2017: Journal of Obstetrics and Gynaecology of India
https://www.readbyqxmd.com/read/28546087/region-specific-oligodendrocyte-transcription-factor-expression-in-a-model-of-neonatal-hypoxic-injury
#4
Bethann M Affeldt, Andre Obenaus, Jonathan Chan, Andrea C Pardo
White matter injury (WMI) of prematurity is associated with a spectrum of neurological disorders ranging from mild cognitive and behavioral deficits to cerebral palsy. Translational studies have implicated impaired oligodendrocyte development after hypoxia as the primary cause of WMI, but the underlying mechanisms remain poorly understood. The goal of this study was to identify alterations in the expression of oligodendrocyte precursor cell transcription factors in a mouse model of transient mild global hypoxia...
May 22, 2017: International Journal of Developmental Neuroscience
https://www.readbyqxmd.com/read/28545834/the-relationship-of-the-subtypes-of-preterm-birth-with-retinopathy-of-prematurity
#5
Anne M Lynch, Brandie D Wagner, Jennifer K Hodges, Tamara S Thevarajah, Emily A Mccourt, Ashlee M Cerda, Naresh Mandava, Ronald S Gibbs, Alan G Palestine
BACKGROUND: Retinopathy of prematurity (ROP) is an adverse outcome of preterm birth (PTB) and is a leading cause of childhood blindness. The relationship between the subtypes of PTB with ROP is understudied. OBJECTIVE: To investigate if there is a difference in the incidence of type 1 or type 2 ROP in infants with PTB resulting from spontaneous preterm labor (SPTL), a medical indication (MIPTB), or preterm-premature rupture of the membranes (PPROM). STUDY DESIGN: A retrospective cohort study of 827 infants screened for ROP who delivered at a single tertiary care center in Colorado...
May 22, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28544065/music-therapy-and-musical-stimulation-in-the-context-of-prematurity-a-narrative-literature-review-from-2010-to-2015
#6
REVIEW
Ambra Palazzi, Camila Canani Nunes, Cesar Augusto Piccinini
AIMS AND OBJECTIVES: This narrative literature review aimed to examine empirical studies of MS and MT carried out with preterm infants and their parents published from 2010 to 2015. BACKGROUND: Prematurity constitutes a global health problem that can impact the development of the preterm infant and the well-being of the parents. Music-based interventions may benefit the infant, parents, and their relationship. In our review, we distinguished between musical stimulation (MS) and music therapy (MT), as we found no previous studies that had made this distinction...
May 25, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28542791/pregnancy-outcomes-among-syrian-refugee-and-jordanian-women-a-comparative-study
#7
K Alnuaimi, M Kassab, R Ali, K Mohammad, K Shattnawi
AIM: To compare pregnancy outcomes of Syrian refugee women and Jordanian women. BACKGROUND AND INTRODUCTION: In the past few years, thousands of Syrians fled Syria to neighbouring countries such as Jordan as a result of the continuing conflict in their country. Pregnant refugee women are facing many difficulties that increase the prevalence of antenatal complications. However, there is limited awareness of whether Syrian refugee women have different risks of pregnancy outcomes than Jordanian women...
May 25, 2017: International Nursing Review
https://www.readbyqxmd.com/read/28542663/-periorbital-pallor-post-application-of-mydriatic-in-infants-with-hydrocephalus-associated-to-systemic-effects
#8
Jorge Luis Alvarado Socarras, Sandra Consuelo Rodríguez
Adequate pupil dilation is needed to evaluate some neonates at risk of developing illness during this stage. However, this procedure is not free of adverse effects, either local or systemic. One of these complications is the local vasoconstriction of the preterm baby’s skin following the application of mydriatic eye drops. OBJECTIVE: To describe secondary local and systemic complications of pharmacological pupil dilation in 2 newborns. Clinical case 1: Full term baby with diagnosis of low-birth weight and hydrocephalia...
April 2017: Revista Chilena de Pediatría
https://www.readbyqxmd.com/read/28542256/maternal-depression-and-anxiety-disorders-mdad-and-child-development-a-manitoba-population-based-study
#9
Brenda Comaskey, Noralou P Roos, Marni Brownell, Murray W Enns, Dan Chateau, Chelsea A Ruth, Okechukwu Ekuma
OBJECTIVE: To examine the association between maternal depression and anxiety disorders (MDAD) and child development assessed during the kindergarten year. METHODS: Administrative data from several health and social databases in Manitoba, Canada, were used to study 18,331 mother-child pairs. MDAD over the period from one year prior to the child's birth to the kindergarten year was defined using physician diagnoses and filled prescriptions. Child development was assessed during the kindergarten year using the Early Development Instrument (EDI) which measures vulnerability across five domains of development...
2017: PloS One
https://www.readbyqxmd.com/read/28539867/prevalence-of-periodontal-disease-its-association-with-systemic-diseases-and-prevention
#10
REVIEW
Muhammad Ashraf Nazir
Periodontal diseases are prevalent both in developed and developing countries and affect about 20-50% of global population. High prevalence of periodontal disease in adolescents, adults, and older individuals makes it a public health concern. Several risk factors such as smoking, poor oral hygiene, diabetes, medication, age, hereditary, and stress are related to periodontal diseases. Robust evidence shows the association of periodontal diseases with systemic diseases such as cardiovascular disease, diabetes, and adverse pregnancy outcomes...
April 2017: International Journal of Health Sciences
https://www.readbyqxmd.com/read/28538042/counterbalanced-comparison-of-the-bsid-ii-and-bayley-iii-at-eighteen-to-twenty-two-months-corrected-age
#11
Meghan Sharp, Sara B DeMauro
OBJECTIVE: To evaluate differences in developmental assessments using the current version of the Bayley Scales of Infant Development (Bayley-III) as compared to the older BSID-II. Previous studies suggest that average scores on the Bayley-III may be significantly higher than scores on the previous version, but the magnitude and potential impact of differences between these 2 assessments are uncertain. METHODS: We enrolled 77 former preterm infants (born <32 wk gestation and ≤2000 g) at 18 to 22 months corrected age in this randomized crossover study...
May 19, 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/28537470/concurrent-validity-of-the-alberta-infant-motor-scale-to-detect-delayed-gross-motor-development-in-preterm-infants-a-comparative-study-with-the-bayley-iii
#12
Plínio Luna de Albuquerque, Miriam Queiroz de Farias Guerra, Marília de Carvalho Lima, Sophie Helena Eickmann
OBJECTIVE: To investigate the concurrent validity of AIMS in relation to the gross motor subtest of the Bayley Scale III/GM in preterm infants. METHODS: A total of 159 gross motor development assessments were performed with the AIMS and Bayley-III/GM. Linear regression was used to assess the correlation between AIMS and Bayley-III/GM scores. The intra-class correlation coefficient (ICC) and the Bland-Altman plot were used to analyze intra- and inter-rater reliability...
May 24, 2017: Developmental Neurorehabilitation
https://www.readbyqxmd.com/read/28536205/severe-retinopathy-of-prematurity-predicts-delayed-white-matter-maturation-and-poorer-neurodevelopment
#13
Torin J A Glass, Vann Chau, Jane Gardiner, Justin Foong, Jillian Vinall, Jill G Zwicker, Ruth E Grunau, Anne Synnes, Kenneth J Poskitt, Steven P Miller
OBJECTIVE: To determine whether severe retinopathy of prematurity (ROP) is associated with (1) abnormal white matter maturation and (2) neurodevelopmental outcomes at 18 months' corrected age (CA) compared with neonates without severe ROP. DESIGN: We conducted a prospective longitudinal cohort of extremely preterm neonates born 24-28 weeks' gestational age recruited between 2006 and 2013 with brain MRIs obtained both early in life and at term-equivalent age. Severe ROP was defined as ROP treated with retinal laser photocoagulation...
May 23, 2017: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/28533037/epidemiology-of-live-born-infants-with-nonimmune-hydrops-fetalis-insights-from-a-population-based-dataset
#14
Martina A Steurer, Shabnam Peyvandi, Rebecca J Baer, Tippi MacKenzie, Ben C Li, Mary E Norton, Laura L Jelliffe-Pawlowski, Anita J Moon-Grady
OBJECTIVE: To evaluate the incidence, etiology, and 1-year mortality of nonimmune hydrops fetalis (NIHF) and to identify risk factors for mortality in a contemporary population-based dataset. STUDY DESIGN: The California Office of Statewide Health Planning and Development maintains a database linking maternal and infant hospital discharge, readmissions, and birth and death certificate date from 1 year before to 1 year after birth. We searched the database (2005-2012) for infants with NIHF (identified by the International Classification of Diseases, 9th Revision, Clinical Modification code)...
May 19, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28533035/trajectories-of-externalizing-and-internalizing-behaviors-in-preterm-children-admitted-to-a-neonatal-intensive-care-unit
#15
Emily D Gerstein, Ashley C Woodman, Cynthia Burnson, Erika R Cheng, Julie Poehlmann-Tynan
OBJECTIVE: To examine the trajectories of internalizing and externalizing behavior problems of preterm children between 16 months and 6 years of age and predictors of trajectories, including gestational age, child dysregulation, maternal depression, socioeconomic status, and parenting. STUDY DESIGN: This longitudinal study followed 148 children and their mothers from neonatal intensive care unit discharge until 6 years of age. Gestational ages ranged from 23 to 36 weeks...
May 19, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28532255/outpatient-vs-inpatient-management-for-superimposed-preeclampsia-without-severe-features-a-retrospective-multicenter-study
#16
Corina N Schoen, Sindy C Moreno, Gabriele Saccone, Nora M Graham, Lauren C Hand, Giuseppe M Maruotti, Pasquale Martinelli, Vincenzo Berghella, Amanda Roman
PURPOSE: To determine if women with preterm superimposed preeclampsia without severe features can be successfully and safely triaged to outpatient management. MATERIALS AND METHODS: This was a multicenter, retrospective, cohort study of singleton pregnancies with superimposed preeclampsia without severe features diagnosed before 37 weeks managed outpatient versus inpatient at Thomas Jefferson University (Philadelphia, USA) and at University of Naples (Naples, Italy) from January 2008 to July 2015...
May 22, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28531098/increase-in-weight-in-low-birth-weight-and-very-low-birth-weight-infants-fed-fortified-breast-milk-versus-formula-milk-a-retrospective-cohort-study
#17
Kris Yuet Wan Lok, Pui Hing Chau, Heidi Sze Lok Fan, Kam Ming Chan, Bill H Chan, Genevieve P C Fung, Marie Tarrant
There has been a dramatic rise in preterm births in developed countries owing to changes in clinical practices and greater use of assisted reproductive techniques. However, few studies have examined the growth and outcomes of preterm infants according to the type of feeding (with fortified breast milk or formula). The purpose of this study was to examine the effect of breast milk feedings and formula on the growth and short-term outcomes of preterm infants in Hong Kong. In a single-center retrospective cohort study, we included 642 preterm infants at gestational age <37 weeks with birth weights <2200 g...
May 20, 2017: Nutrients
https://www.readbyqxmd.com/read/28528963/neuronal-activity-patterns-in-the-developing-barrel-cortex
#18
Heiko J Luhmann, Rustem Khazipov
The developing barrel cortex reveals a rich repertoire of neuronal activity patterns, which have been also found in other sensory neocortical areas and in other species including the somatosensory cortex of preterm human infants. The earliest stage is characterized by asynchronous, sparse single cell firing at low frequencies. During the second stage neurons show correlated firing, which is initially mediated by electrical synapses and subsequently transforms into network bursts depending on chemical synapses...
May 18, 2017: Neuroscience
https://www.readbyqxmd.com/read/28527571/progesterone-receptor-signaling-in-uterine-myometrial-physiology-and-preterm-birth
#19
San-Pin Wu, Francesco J DeMayo
Myometrium holds the structural integrity for the uterus and generates force for parturition with its primary component, the smooth muscle cells. The progesterone receptor mediates progesterone-dependent signaling and connects to a network of pathways for regulation of contractility and inflammatory responses in myometrium. Dysfunctional progesterone signaling has been linked to pregnancy complications including preterm birth. In the present review, we summarize recent findings on modifiers and effectors of the progesterone receptor signaling...
2017: Current Topics in Developmental Biology
https://www.readbyqxmd.com/read/28527570/mechanisms-of-glucocorticoid-action-during-development
#20
Jonathan T Busada, John A Cidlowski
Glucocorticoids are primary stress hormones produced by the adrenal cortex. The concentration of serum glucocorticoids in the fetus is low throughout most of gestation but surge in the weeks prior to birth. While their most well-known function is to stimulate differentiation and functional development of the lungs, glucocorticoids also play crucial roles in the development of several other organ systems. Mothers at risk of preterm delivery are administered glucocorticoids to accelerate fetal lung development and prevent respiratory distress...
2017: Current Topics in Developmental Biology
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