Xuming Zhou, Hezhen Zhu, Cong Luo, Zhaojie Yan, Guansong Zheng, Xiaofeng Zou, Junrong Zou, Guoxi Zhang
RNA modification is a post-transcriptional level of regulation that is widely distributed in all types of RNAs, including mRNA, tRNA, rRNA, miRNA, and lncRNA, where N6-methyladenine (m6 A) is the most abundant mRNA methylation modification. Significant evidence has depicted that m6 A modifications are closely related to human diseases, especially cancer, and play pivotal roles in RNA transcription, splicing, stabilization, and translation processes. The most common urological cancers include prostate, bladder, kidney, and testicular cancers, accounting for a certain proportion of human cancers, with an ever-increasing incidence and mortality...
December 20, 2023: Discover. Oncology