Jean-Baptiste Bossard, Jean-Baptiste Beuscart, Marie Robin, Mohamad Mohty, Fiorenza Barraco, Patrice Chevallier, Tony Marchand, Marie-Thérèse Rubio, Amandine Charbonnier, Didier Blaise, Jacques-Olivier Bay, Carmen Botella-Garcia, Gandhi Damaj, Florence Beckerich, Patrice Ceballos, Thomas Cluzeau, Jérôme Cornillon, Mathieu Meunier, Corentin Orvain, Alain Duhamel, Federico Garnier, Jean-Jacques Kiladjian, Ibrahim Yakoub-Agha
The value of pretransplant splenectomy in patients with myelofibrosis (MF) is subject to debate, since the procedure may preclude subsequent allogeneic hematopoietic cell transplantation (allo-HCT). To determine the impact of pretransplant splenectomy on the incidence of allo-HCT, we conducted a comprehensive retrospective study of all patients with MF for whom an unrelated donor search had been initiated via the French bone marrow transplantation registry (RFGM) between 1 January 2008 and 1 January 2017. Additional data were collected from the patients' medical files and a database held by the French-Language Society for Bone Marrow Transplantation and Cell Therapy (SFGM-TC)...
January 2021: American Journal of Hematology