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Autograft

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https://www.readbyqxmd.com/read/29145340/open-repair-of-intraoperative-popliteal-artery-injury-during-total-knee-arthroplasty-in-a-patient-with-severe-hemophilia-a-a-case-report-and-literature-review
#1
Bin Feng, Ke Xiao, Jiang Shao, Yu Fan, Xisheng Weng
RATIONALE: Arterial injuries during total knee arthroplasty (TKA) though rare may occur. Hemophilia may further challenge the management of such injury. PATIENT CONCERNS: A 48-year-old male patient with severe hemophilia type A and stiff knee arthropathy underwent bilateral TKAs. Left popliteal artery injury was detected at the end of the left TKA. DIAGNOSES: Urgent angiography confirmed the diagnosis of the left popliteal artery transection...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29144832/postoperative-complications-of-dermis-fat-autografts-in-the-anophthalmic-socket
#2
Victoria Starks, Suzanne K Freitag
Reconstruction of the anophthalmic socket allows the use of an ocular prosthesis and rehabilitation of facial appearance. Dermis-fat grafting is one option in volume augmentation of the anophthalmic socket and presents unique benefits, including increased surface area within the socket and the ability to grow with pediatric patients. Postoperative complications of this procedure are relatively common. Minor complications, such as graft hirsutism, keratinization, and conjunctival cysts or granulomas, are managed easily by observation or simple intervention...
November 16, 2017: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/29143524/injectable-shear-thinning-caso4-fgf-18-incorporated-chitin-plga-hydrogels-enhances-bone-regeneration-in-mice-cranial-bone-defect-model
#3
Sivashanmugam Amirthalingam, Pornkawee Charoenlarp, Sankar Deepthi, ArunKumar Rajendran, Shantikumar V Nair, Sachiko Iseki, Rangasamy Jayakumar
For craniofacial bone regeneration, shear thinning injectable hydrogels are favoured over conventional scaffolds due to their improved defect margin adaptability, easier handling and ability to be injected manually into deeper tissues. The most accepted method, after autografting, is the use of recombinant human BMP-2; however, complications such as inter-individual variations, edema, and poor cost-efficiency in supraphysiological doses have been reported. The endogenous synthesis of BMP-2 is desirable, and a molecule which induces this is FGF-18 since it can up-regulate the BMP-2 expression and positively modulate other osteogenic genes...
November 16, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29138919/low-re-rupture-rate-with-bptb-autograft-and-semitendinosus-gracilis-autograft-with-preserved-insertions-in-acl-reconstruction-surgery-in-sports-persons
#4
Ravi Gupta, Munish Sood, Anubhav Malhotra, Gladson David Masih, Anil Kapoor, Mukta Raghav, Mehar Dhillon
PURPOSE: To compare the results of bone-patellar tendon-bone graft (BPTB), semitendinosus-gracilis graft with preserved insertions (STGPI) and semitendinosus-gracilis-free graft (STGF) in terms of graft failure, objective mechanical stability, functional outcome, and return to sports in elite and recreational sports persons. It was hypothesized that the STGPI graft provided superior outcome as compared to the other two grafts. METHODS: Two hundred and forty-nine elite and recreational players who underwent ACL reconstruction surgery, with BPTB graft (N = 80), STGPI graft (N = 85), and STGF graft (N = 84) with a minimum follow-up of 2 years, were assessed using clinical tests, knee arthrometer (KT 1000™), single-leg hop test, Lysholm knee score, Tegner's activity scale, and return to sports...
November 14, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29131557/comparison-of-self-made-cryopreservative-fibrin-glue-and-commercial-fibrin-glue-kit-in-pterygium-surgery-1-year-follow-up
#5
Jingwen Gong, Jiaqi Fan, Ting Shen, Jin Jiang
PURPOSE: To assess long-term efficacy and safety of self-made cryopreservative fibrin glue (SMC) applied in pterygium surgery. METHODS: Prospective, comparative, interventional case series. Forty eyes of 40 patients with nasal primary pterygium, 24 male and 16 female, were enrolled. The patients were assigned to two groups and each contained 12 male and eight female based on the pterygium area encroaching onto the cornea. In one group, the conjunctival autograft was attached to the sclera with SMC stored for 2 months, and in the other group, commercial fibrin glue kit (CK) was applied after the pterygium was removed...
November 13, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/29129272/incidence-and-risk-factors-for-infection-in-spine-surgery-a-prospective-multicenter-study-of-1764-instrumented-spinal-procedures
#6
Wenfei Gu, Laiyong Tu, Zhiquan Liang, Zhenbin Wang, Kahaer Aikenmu, Ge Chu, Enfeng Zhang, Jiang Zhao
BACKGROUND: Surgical site infection (SSI) is a common complication in spinal surgery, imposing a high burden on patients and society. However, information about its characteristics and related risk factors is limited. We designed this prospective, multicenter study to address this issue. METHODS: From January 2015 through February 2016, a total of 1764 patients who had spinal trauma or degenerative spinal diseases were treated with instrumented surgeries and followed up for 1 year with complete data...
November 9, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/29125428/schwann-cells-and-mesenchymal-stem-cells-in-laminin-or-fibronectin-aligned-matrices-and-regeneration-across-a-critical-size-defect-of-15-mm-in-the-rat-sciatic-nerve
#7
Francisco Gonzalez-Perez, Joaquim Hernández, Claudia Heimann, James B Phillips, Esther Udina, Xavier Navarro
OBJECTIVE Artificial nerve guides are being developed to substitute for autograft repair after peripheral nerve injuries. However, the use of conduits is limited by the length of the gap that needs to be bridged, with the success of regeneration highly compromised in long gaps. Addition of aligned proregenerative cells and extracellular matrix (ECM) components inside the conduit can be a good strategy to achieve artificial grafts that recreate the natural environment offered by a nerve graft. The purpose of this study was to functionalize chitosan devices with different cell types to support regeneration in limiting gaps in the rat peripheral nerve...
November 10, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/29122282/masquelet-technique-with-external-locking-plate-for-recalcitrant-distal-tibial-nonunion
#8
Ching-Hou Ma, Yen-Chun Chiu, Kun-Ling Tsai, Yuan-Kun Tu, Cheng-Yo Yen, Chin-Hsien Wu
OBJECTIVE: In the present retrospective study, we aimed to analyze the results of treatment for recalcitrant distal tibial nonunion using Masquelet technique with locking plate as a definitive external fixator. MATERIALS: We included 15 consecutive cases of distal tibial nonunion treated at our hospital between January 2012 and December 2015. The reconstructive procedure comprised debridement of the nonunion site, deformity correction, stabilization with an external locked plate, defect filling with cement spacer for inducing membrane formation, and bone reconstruction using a cancellous bone autograft (Masquelet technique)...
October 26, 2017: Injury
https://www.readbyqxmd.com/read/29122086/endonasal-endoscopic-management-of-frontal-sinus-cerebrospinal-fluid-leak
#9
Javaneh Jahanshahi, Mehdi Zeinalizadeh, Hasan Reza Mohammadi, Seyed Mousa Sadrehosseini
BACKGROUND: A frontal sinus leak is uncommon and is seen in ∼15% of cases of patients with cerebrospinal fluid (CSF) rhinorrhea. Now, endonasal endoscopic techniques have been reported to reconstruct skull base defects in the frontal sinus with a favorable outcome. OBJECTIVE: To review our experience in the repair of frontal sinus CSF leaks through an endonasal endoscopic approach. METHODS: Twenty-four patients with a frontal sinus leak who underwent endonasal endoscopic repair entered the study...
November 1, 2017: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29119044/nursing-review-of-diagnosis-and-treatment-of-lumbar-degenerative-spondylolisthesis
#10
Nancy E Epstein, Renee D Hollingsworth
Background: In the lumbar spine, degenerative spondylolisthesis or degenerative (not traumatic) slippage of one vertebral body over another is divided into 4 grades - grade I (25%), grade II (50%), grade III (75%), and grade IV (100%). Dynamic X-rays, magnetic resonance (MR), and computed tomography (CT) scans document the slip secondary to arthritic changes of the facet joint plus stenosis, ossification of the yellow ligament, disc herniations, and synovial cysts. MR best demonstrates soft tissue pathology whereas CT better delineates ossific/calcified disease...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/29117846/lunotriquetral-ligament-reconstruction-utilizing-a-palmaris-longus-autograft
#11
Carl M Harper, Matthew L Iorio
Injury to the lunotriquetral ligament can result in midcarpal instability, with resultant alterations in normal wrist kinematics and subsequent arthrosis. We performed a previously undescribed technique of lunotriquetral ligament reconstruction in two patients utilizing a palmaris longus tendon autograft. Average age at presentation was 24 years old with a mean follow up of 10 months. Average range of motion was 62.5° of flexion and 57.5° of extension. Total arc of motion was 83% of the contralateral uninvolved extremity...
December 2017: Journal of Hand Surgery Asian-Pacific Volume
https://www.readbyqxmd.com/read/29117721/enhanced-sciatic-nerve-regeneration-by-human-endometrial-stem-cells-in-an-electrospun-poly-%C3%AE%C2%B5-caprolactone-collagen-nbg-nerve-conduit-in-rat
#12
Forouzan Mohamadi, Somayeh Ebrahimi-Barough, Mohammad Reza Nourani, Korosh Mansoori, Majid Salehi, Ali Akbar Alizadeh, Seyed Mohammad Tavangar, Farshid Sefat, Siavash Sharifi, Jafar Ai
In recent years, for neurodegenerative diseases therapy, research has focused on the stem cells therapy. Due to promising findings in stem cell therapy, there are various sources of stem cells for transplantation in human. The aim of this study was to evaluate sciatic nerve regeneration in the rat after nerve transaction followed by human endometrial stem cells (hEnSCs) treatment into poly (e-caprolactone)/collagen/nanobioglass (PCL/collagen/NBG) nanofibrous conduits. After treatment of animals, the performance in motor and sensory tests, showed significant improvement in rats treated with hEnSCs as an autograft...
November 8, 2017: Artificial Cells, Nanomedicine, and Biotechnology
https://www.readbyqxmd.com/read/29115445/mir%C3%A2-126-is-essential-for-endothelial-phenotype-expression-during-endothelial-differentiation-in-adipose%C3%A2-derived-stem-cells
#13
Han Xie, Fang Wang, Xiao Chen, Hao Ying
The endothelial differentiation of stem cells serves an essential role in vascular development, function and disease. Autograft adipose‑derived stem cells (ADSCs) may be a novel source of cell for use in the study of angiogenesis. microRNA‑126 (miR‑126) has been extensively studied in endothelial cells. However, the effect of miR‑126 on the endothelial differentiation of ADSCs has not been demonstrated. In the present study, it was observed that the expression of miR‑126 was markedly increased during the endothelial differentiation of ADSCs in a time‑dependent manner...
October 27, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29114628/femoral-tunnel-positioning-in-anterior-cruciate-ligament-reconstruction-anteromedial-portal-versus-transtibial-technique-a-randomized-clinical-trial
#14
Michele Venosa, Marco Delcogliano, Roberto Padua, Federica Alviti, Antonio Delcogliano
Purpose  The purpose of this study was to investigate, through three-dimensional computed tomography (3D-CT), the accuracy of femoral tunnel positioning in patients undergoing anterior cruciate ligament (ACL) reconstruction, comparing transtibial (TT) and anteromedial (AM) techniques. Methods  We evaluated postoperative 3D-CT scans of 26 patients treated with ACL reconstruction with hamstrings autograft using a low accessory AM portal technique and 26 treated with the TT technique. The position of the femoral tunnel center was measured with the quadrant method...
March 2017: Joints
https://www.readbyqxmd.com/read/29114625/revision-anterior-cruciate-ligament-reconstruction-with-contralateral-hamstring-tendon-grafts-6-years-follow-up
#15
Claudio Legnani, Stefania Zini, Enrico Borgo, Alberto Ventura
Purpose  The purpose of this study was to retrospectively evaluate the clinical outcome of revision anterior cruciate ligament (ACL) reconstruction with contralateral hamstring tendon autografts, specifically with regard to patient satisfaction, return to preinjury activity level, and postoperative functional outcomes. Methods  Between 2004 and 2011, 23 patients underwent revision ACL reconstruction with contralateral autogenous hamstring tendon grafts and were retrospectively reviewed at an average follow-up of 6...
March 2017: Joints
https://www.readbyqxmd.com/read/29114339/lateral-antebrachial-cutaneous-nerve-as-a-donor-source-for-digital-nerve-grafting-a-concept-revisited
#16
Mehmet Bekir Unal, Kemal Gokkus, Evrim Sirin, Eren Cansü
Objective: The main objective of this study is to evaluate the availability of lateral antebrachial cutaneous nerve (LACN) autograft for acute or delayed repair of segmented digital nerve injuries. Patients and Methods: 13 digital nerve defects of 11 patients; treated with interposition of LACN graft that harvested from ipsilateral extremity were included in the study. Mean follow up period was 35, 7 months. The mean time from injury to grafting is 53, 3 days. The results of the mean 2PDT and SWMT values of injured /uninjured finger at the end of follow up period were evaluated with Paired T test...
2017: Open Orthopaedics Journal
https://www.readbyqxmd.com/read/29106911/stem-cells-niches-and-scaffolds-applications-to-burns-and-wound-care
#17
Suzanne M Watt, Jonathan M Pleat
The importance of skin to survival, and the devastating physical and psychological consequences of scarring following reparative healing of extensive or difficult to heal human wounds, cannot be disputed. We discuss the significant challenges faced by patients and healthcare providers alike in treating these wounds. New state of the art technologies have provided remarkable insights into the role of skin stem and progenitor cells and their niches in maintaining skin homeostasis and in reparative wound healing...
October 26, 2017: Advanced Drug Delivery Reviews
https://www.readbyqxmd.com/read/29105943/characterization-of-printed-pla-scaffolds-for-bone-tissue-engineering
#18
Agathe Grémare, Vera Guduric, Reine Bareille, Valérie Heroguez, Simon Latour, Nicolas L'Heureux, Jean-Christophe Fricain, Sylvain Catros, Damien Le Nihouannen
Autografts remain the gold standard for orthopedic transplantations. However, to overcome its limitations, bone tissue engineering proposes new strategies. This includes the development of new biomaterials such as synthetic polymers, to serve as scaffold for tissue production. The objective of this present study was to produce poly(lactic) acid (PLA) scaffolds of different pore size using fused deposition modeling (FDM) technique and to evaluate their physicochemical and biological properties. Structural, chemical, mechanical and biological characterizations were performed...
November 6, 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/29103890/large-osseous-defect-reconstruction-using-a-custom-three-dimensional-printed-titanium-truss-implant
#19
Eric So, Vincent H Mandas, Lee Hlad
Treatment of large osseous defects remains a difficult surgical challenge. Autografts and allografts have been known to undergo late collapse, because these options are not specifically designed to withstand the high loads of the foot and ankle. The inability to achieve the correct shape for reconstruction further limits their application. Large osseous defects will result during salvage after failed Lapidus bunionectomy, explantation of failed total ankle replacements, and nonunion of Evans calcaneal osteotomy...
November 2, 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29103840/the-influence-of-full-thickness-chondral-defects-on-outcomes-following-meniscal-allograft-transplantation-a-comparative-study
#20
Bryan M Saltzman, Maximilian A Meyer, Timothy S Leroux, Matthew E Gilelis, Margot Debot, Adam B Yanke, Brian J Cole
PURPOSE: To compare a series of patients who underwent meniscus allograft transplantation (MAT) with full-thickness chondral defects (FTD) with those with no chondral defect (ND) with regard to the following: change in patient-reported outcomes (PROs) from baseline to 2-year follow-up and baseline to the final follow-up (including comparisons to minimal clinically important differences), complications and complication rates, reoperations and reoperation rates/timing, and failures and time to failure (revision MAT or conversion to total knee arthroplasty)...
November 2, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
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