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https://www.readbyqxmd.com/read/27920334/technique-for-use-of-trabecular-metal-spacers-in-tibiotalocalcaneal-arthrodesis-with-large-bony-defects
#1
Christopher Kreulen, Evan Lian, Eric Giza
There are many causes of large bone defects in the tibiotalar joint that need to be definitively treated with a tibiotalocalcaneal (TTC) arthrodesis. Some of the challenges of a large defect are its effect on leg length and the complications associated with trying to fill the defect with structural bone graft. We present an operative strategy involving the use of a trabecular metal implant, a TTC nail that utilized 2 forms of compression, and Reamer/Irrigator/Aspirator (RIA) autograft, to address limitations of previous operative approaches and reliably treat this operative challenge...
December 5, 2016: Foot & Ankle International
https://www.readbyqxmd.com/read/27920332/comparison-of-ankle-fusion-rates-with-and-without-anterior-plate-augmentation
#2
Phillip M Mitchell, Diana G Douleh, A Brian Thomson
BACKGROUND: The optimal fixation construct for tibiotalar arthrodesis continues to be debated. While biomechanical data and clinical series support anterior plate augmentation, comparative studies assessing its use are sparse. The purpose of this study was to compare the rates of successful tibiotalar arthrodesis with and without anterior plate augmentation of a compression screw construct. METHODS: We studied 64 patients (65 ankles) undergoing tibiotalar arthrodesis done by a single surgeon over a 10-year period (2006-2016) with anterior plate augmentation beginning in 2010...
December 5, 2016: Foot & Ankle International
https://www.readbyqxmd.com/read/27919994/clinical-outcome-of-reconstruction-using-frozen-autograft-for-a-humeral-bone-tumor
#3
Hiroaki Kimura, Norio Yamamoto, Toshiharu Shirai, Hideji Nishida, Katsuhiro Hayashi, Yoshikazu Tanzawa, Akihiko Takeuchi, Shinji Miwa, Hiroyuki Tsuchiya
BACKGROUND: We developed a frozen autograft technique in which a tumor-bearing bone was treated with liquid nitrogen for reconstruction. The purpose of this study was to evaluate the functional outcomes of this technique after resection of humeral bone tumors. PATIENTS AND METHODS: Eight patients were included in the study. The freezing range was classified into 2 groups, depending on whether the joint surface of the humeral head was frozen. RESULTS: In the joint freezing group, the mean active shoulder abduction and flexion were 43...
December 2016: Anticancer Research
https://www.readbyqxmd.com/read/27919798/femtosecond-laser-assisted-conjunctival-autograft-preparation-for-pterygium-surgery
#4
REVIEW
Matthias Fuest, Yu-Chi Liu, Gary Hin-Fai Yam, Ericia Pei Wen Teo, Hla Myint Htoon, Minas T Coroneo, Jodhbir S Mehta
PURPOSE: Pterygium is a common ocular surface disorder. Conjunctival autografting (CAG) following pterygium resection is the gold standard treatment. CAGs without Tenon's tissue provide better results but are more technically difficult to achieve. In this study, we evaluated the feasibility and reproducibility of femtosecond laser (FSL)-assisted CAG preparation. METHODS: Fifteen porcine globes were fixed in a suction holder and CAGs of different diameters were created by 1) an experienced consultant and 2) a less experienced fellow using the Ziemer LDV Z8...
December 2, 2016: Ocular Surface
https://www.readbyqxmd.com/read/27919129/-a-case-of-recurrent-renal-cancer-in-the-autografted-kidney-treated-with-percutaneous-cryoablation
#5
Eisuke Tomiyama, Shinichiro Fukuhara, Takeshi Ujike, Akira Nagahara, Motohide Uemura, Hiroshi Kiuchi, Ryoichi Imamura, Yasushi Miyagawa, Mikio Nin, Norio Nonomura
We report a case of recurrent renal cancer in the autografted kidney, treated with percutaneous cryoablation. A 59-year-old man who had bilateral renal tumors underwent radical left nephrectomy, ex vivo right partial nephrectomy and auto-transplantation at the right ileal fossa in our hospital 11 years ago. Histopathological examination showed clear cell renal cell carcinoma in bilateral kidneys (pT1bN0M0). He had been followed at another hospital without tumor recurrence for 11 years. In 2014, an enhanced CT scan revealed a renal tumor with a diameter of two centimeters in the autografted kidney, which was thought to be a recurrence of the initial renal cancer...
October 2016: Hinyokika Kiyo. Acta Urologica Japonica
https://www.readbyqxmd.com/read/27915981/molecular-cellular-and-pharmaceutical-aspects-of-autologous-grafts-for-peri-implant-hard-and-soft-tissue-defects
#6
Jiayu Lu, Yongming Hao, Wei Zhao, Chengqi Lv, Derong Zou
The lack of supporting hard and soft tissues always prevents the rehabilitation with dental implants. Among various hard and soft tissue augmentation procedures, autologous grafts have been considered to be the gold standard. Autologous mesenchymal stem cells (MSCs) from bone marrow, dental tissue and adipose tissue have been described as promising alternatives for bone regeneration in the field of dental implantation. Mucosal cells, gingival fibroblasts and dental progenitor cells (DPS) can enhance peri-implant soft tissue augmentation and regenerate periodontal tissues around dental implants...
December 1, 2016: Current Pharmaceutical Biotechnology
https://www.readbyqxmd.com/read/27911983/fibrin-glue-versus-sutures-for-conjunctival-autografting-in-primary-pterygium-surgery
#7
REVIEW
Vito Romano, Mario Cruciani, Luigi Conti, Luigi Fontana
BACKGROUND: Pterygium, a growth of the conjunctiva over the cornea, is a progressive disease leading in advanced stages to visual impairment, restriction of ocular motility, chronic inflammation and cosmetic concerns. Surgical removal is the treatment of choice, but recurrence can be a problem. Currently the best surgical option in terms of recurrence is conjunctival autograft. To date the most common surgical methods of attaching conjunctival autografts to the sclera are through suturing or fibrin glue...
December 2, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27909676/anatomic-double-bundle-anterior-cruciate-ligament-reconstruction-with-a-free-quadriceps-tendon-autograft
#8
Sergiu Caterev, Dan Viorel Nistor, Adrian Todor
Anatomic double-bundle anterior cruciate ligament (ACL) reconstruction aims to restore the 2 functional bundles of the ACL in an attempt to better reproduce the native biomechanics of the injured knee and promote long-term knee health. However, this concept is not fully accepted and is not performed on a standard basis. In addition, the superiority of this technique over the conventional single-bundle technique has been questioned, especially the long-term clinical results. One of the down sides of the double-bundle reconstruction is the complexity of the procedure, with increased risks, operative time, and costs compared with the single-bundle procedure...
October 2016: Arthroscopy Techniques
https://www.readbyqxmd.com/read/27909665/autologous-osteophyte-grafting-for-open-wedge-high-tibial-osteotomy
#9
Takenori Akiyama, Ken Okazaki, Taro Mawatari, Satoshi Ikemura, Shunsuke Nakamura
Osteophytes are physiological bony outgrowths that develop at the margins of the articular surfaces during the progression of osteoarthritis; they are associated with active endochondral bone formation processes and expressions of various growth factors. We believe they could be a source of bone grafts as a result of a potentially strong osteoinductive effect. Moreover, osteophytes can be easily harvested by arthroscopy in patients undergoing open-wedge high tibial osteotomy (OW-HTO) for medial unicompartmental knee osteoarthritis...
October 2016: Arthroscopy Techniques
https://www.readbyqxmd.com/read/27909662/osteochondral-autograft-transfer-technique-for-glenoid-osteochondral-defect
#10
Douglas J Wyland, Clint Beicker
Glenoid osteochondral defects can be a significant source of pain and disability in an active population. Many treatments are available, but most joint-preserving procedures are limited to debridement, abrasion chondroplasty, or marrow-stimulation techniques, all of which depend on healthy underlying bone and none of which address underlying bony pathology. Osteochondral autograft transfer has been a successful form of treatment for lesions in the knee, elbow, and ankle, especially when subchondral bone is involved...
October 2016: Arthroscopy Techniques
https://www.readbyqxmd.com/read/27909654/bone-substitutes-and-expanders-in-spine-surgery-a-review-of-their-fusion-efficacies
#11
Abhijeet Kadam, Paul W Millhouse, Christopher K Kepler, Kris E Radcliff, Michael G Fehlings, Michael E Janssen, Rick C Sasso, James J Benedict, Alexander R Vaccaro
STUDY DESIGN: A narrative review of literature. OBJECTIVE: This manuscript intends to provide a review of clinically relevant bone substitutes and bone expanders for spinal surgery in terms of efficacy and associated clinical outcomes, as reported in contemporary spine literature. SUMMARY OF BACKGROUND DATA: Ever since the introduction of allograft as a substitute for autologous bone in spinal surgery, a sea of literature has surfaced, evaluating both established and newly emerging fusion alternatives...
2016: International Journal of Spine Surgery
https://www.readbyqxmd.com/read/27906458/autologous-stem-cell-transplantation-for-adult-acute-myelocytic-leukemia-in-first-remission-better-outcomes-after-busulfan-and-melphalan-compared-with-busulfan-and-cyclophosphamide-a-retrospective-study-from-the-acute-leukemia-working-party-of-the-european
#12
Norbert-Claude Gorin, Myriam Labopin, Tomasz Czerw, Thomas Pabst, Didier Blaise, Pierre-Yves Dumas, Damir Nemet, William Arcese, Silvia Maria Trisolini, Depei Wu, Anne Huynh, Tsila Zuckerman, Ellen Meijer, Seckin Cagirgan, Jan Cornelissen, Mohamed Houhou, Emmanuelle Polge, Mohamad Mohty, Arnon Nagler
BACKGROUND: Autologous stem cell transplantation (ASCT) for adult acute myelogenous leukemia (AML) is a valid therapeutic option for patients with good-risk and intermediate-risk disease. The authors used the registry of the European Society for Blood and Marrow Transplantation to compare combined busulfan and melphalan (BUMEL) with combined busulfan and cyclophosphamide (BUCY) before transplantation. METHODS: From 2005 to 2013, 853 patients with available cytogenetics underwent ASCT in first remission, including 257 after receiving BUMEL and 596 after receiving BUCY...
December 1, 2016: Cancer
https://www.readbyqxmd.com/read/27906436/iliac-crest-bone-graft-a-23-years-hystory-of-infection-at-donor-site-in-vertebral-arthrodesis-and-a-review-of-current-bone-substitutes
#13
L Babbi, G Barbanti-Brodano, A Gasbarrini, S Boriani
OBJECTIVE: This is an exemplary case report underlining a relevant morbidity which could be associated to the use of autologous iliac crest bone graft (ICBG) for spine fusion. CASE REPORT: Starting from 1990, a 25-years-old woman underwent two subsequent surgical treatments for non-Hodgkin lymphoma vertebral localizations. In the second surgery, arthrodesis was obtained with autograft through right posterior iliac crest osteotomy. During the chemotherapy treatment following the surgery, the patient suffered from infection at posterior iliac crest scar, the site of previous graft, caused by methicillin-resistant Staphylococcus aureus...
November 2016: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/27903823/in%C3%A2-vitro-skin-models-and-tissue-engineering-protocols-for-skin-graft-applications
#14
REVIEW
Lucas B Naves, Chetna Dhand, Luis Almeida, Lakshminarayanan Rajamani, Seeram Ramakrishna
In this review, we present a brief introduction of the skin structure, a concise compilation of skin-related disorders, and a thorough discussion of different in vitro skin models, artificial skin substitutes, skin grafts, and dermal tissue engineering protocols. The advantages of the development of in vitro skin disorder models, such as UV radiation and the prototype model, melanoma model, wound healing model, psoriasis model, and full-thickness model are also discussed. Different types of skin grafts including allografts, autografts, allogeneic, and xenogeneic are described in detail with their associated applications...
November 30, 2016: Essays in Biochemistry
https://www.readbyqxmd.com/read/27903590/anterior-cruciate-ligament-derived-stem-cells-transduced-with-bmp2-accelerate-graft-bone-integration-after-acl-reconstruction
#15
Yohei Kawakami, Koji Takayama, Tomoyuki Matsumoto, Ying Tang, Bing Wang, Yutaka Mifune, James H Cummins, Ryan J Warth, Ryosuke Kuroda, Masahiro Kurosaka, Freddie H Fu, Johnny Huard
BACKGROUND: Strong graft-bone integration is a prerequisite for successful graft remodeling after reconstruction of the anterior cruciate ligament (ACL) using soft tissue grafts. Novel strategies to accelerate soft tissue graft-bone integration are needed to reduce the need for bone-tendon-bone graft harvest, reduce patient convalescence, facilitate rehabilitation, and reduce total recovery time after ACL reconstruction. HYPOTHESIS: The application of ACL-derived stem cells with enhanced expression of bone morphogenetic protein 2 (BMP2) onto soft tissue grafts in the form of cell sheets will both accelerate and improve the quality of graft-bone integration after ACL reconstruction in a rat model...
November 30, 2016: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/27900339/an-ecological-study-of-anterior-cruciate-ligament-reconstruction-part-1-clinical-tests-do-not-correlate-with-return-to-sport-outcomes
#16
Timothy M McGrath, Gordon Waddington, Jennie M Scarvell, Nick Ball, Rob Creer, Kevin Woods, Damian Smith, Roger Adams
BACKGROUND: Additional high-quality prospective studies are needed to better define the objective criteria used in relation to return-to-sport decisions after synthetic (ligament advanced reinforcement system [LARS]) and autograft (hamstring tendon [2ST/2GR]) anterior cruciate ligament (ACL) reconstruction in active populations. PURPOSE: To prospectively investigate and describe the recovery of objective clinical outcomes after autograft (2ST/2GR) and synthetic (LARS) ACL reconstructions, as well as to investigate the relationship between these clinimetric test outcomes and return-to-sport activity (Tegner activity scale [TAS] score) at 12 and 24 months postoperatively...
November 2016: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/27900338/the-bridge-enhanced-anterior-cruciate-ligament-repair-bear-procedure-an-early-feasibility-cohort-study
#17
Martha M Murray, Brett M Flutie, Leslie A Kalish, Kirsten Ecklund, Braden C Fleming, Benedikt L Proffen, Lyle J Micheli
BACKGROUND: This study assessed the safety of the newly developed bridge-enhanced anterior cruciate ligament (ACL) repair (BEAR), which involves suture repair of the ligament combined with a bioactive scaffold to bridge the gap between the torn ligament ends. As the intra-articular environment is complex in its response to implanted materials, this study was designed to determine whether there would be a significant rate of adverse reaction to the implanted scaffold. HYPOTHESIS: The primary hypothesis was that the implanted scaffold would not result in a deep joint infection (arthrocentesis with positive culture) or significant inflammation (clinical symptoms justifying arthrocentesis but negative culture)...
November 2016: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/27900098/clinical-effects-of-three-surgical-approaches-for-a-giant-cell-tumor-of-the-distal-radius-and-ulna
#18
Jing Zhang, Yi Li, Dongqi Li, Junfeng Xia, Su Li, Shunling Yu, Yedan Liao, Xiaojuan Li, Huilin Li, Zuozhang Yang
The aim of the present study was to assess the curative effects of three surgical approaches for a giant cell tumor (GCT) of the distal radius and ulna. A total of 27 patients with GCT on distal radius and ulnas (7 and 20, respectively), confirmed by biopsy, were treated with individualized treatment regimens, according to the Campanacci's grade system: i) Curettage plus inactivated tumor bed and allogeneic bone graft/bone cement augmentation for Campanacci's grade I GCT of the distal radius and ulna (Group A); ii) simple en bloc resection for Campanacci's grade II and III GCT of the distal ulna (Group B); iii) en bloc resection and reconstruction with non-vascularized fibular autograft/allogeneic bone graft for Campanacci's II and III GCT of the distal radius (Group C)...
November 2016: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/27899356/donor-site-morbidity-after-lateral-ankle-ligament-reconstruction-using-the-anterior-half-of-the-peroneus-longus-tendon-autograft
#19
Chul Hyun Park, Woo-Chun Lee
BACKGROUND: The anterior half of the peroneus longus tendon (AHPLT) has been reported to be an effective autograft for ligament reconstruction with respect to strength and safety. However, there is little information regarding donor site morbidity after harvesting the AHPLT. Furthermore, to the best of our knowledge, there has not been a study on the isokinetic evaluation of ankle plantar flexion and eversion after AHPLT harvesting. PURPOSE: To evaluate the clinical and radiographic results after lateral ankle ligament reconstruction using the AHPLT...
November 29, 2016: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/27896458/prognostic-factors-in-the-treatment-of-carpal-scaphoid-non-unions
#20
F Schuind, F Moungondo, W El Kazzi
In this literature review, the authors analyse the prognostic factors in the curative treatment of scaphoid non-unions. The main negative prognostic factors are smoking, the time elapsed since the fracture, and avascular necrosis of the proximal fragment. If the latter is present, the revascularization by a pedicle or microsurgical bone autograft is probably the treatment of choice. In non-unions without evidence of osteonecrosis, vascularized bone grafts are probably not superior to conventional bone grafts, which can presently be performed under arthroscopic control, with minimal morbidity...
November 28, 2016: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
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