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Glioblastoma AND surgical complication

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https://www.readbyqxmd.com/read/28806622/case-report-on-the-non-operative-management-of-a-retrievable-inferior-vena-cava-filter-perforating-the-duodenum
#1
Joseph S Fernandez-Moure, Keemberly Kim, M Haseeb Zubair, Wade R Rosenberg
INTRODUCTION: Deep vein thrombosis (DVT) continues to be a significant source of morbidity for surgical patients. Placement of a retrievable inferior vena cava (IVC) filter is used when patients have contraindications to anticoagulation or recurrent pulmonary embolism despite therapeutic anticoagulation. Although retrievable IVC filters are often used, they carry a unique set of risks. PRESENTATION OF CASE: A 67-year-old man presents to the Emergency Room (ER) following large volume melena and complaining of syncope...
July 10, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28689368/maximize-surgical-resection-beyond-contrast-enhancing-boundaries-in-newly-diagnosed-glioblastoma-multiforme-is-it-useful-and-safe-a-single-institution-retrospective-experience
#2
Federico Pessina, Pierina Navarria, Luca Cozzi, Anna Maria Ascolese, Matteo Simonelli, Armando Santoro, Elena Clerici, Marco Rossi, Marta Scorsetti, Lorenzo Bello
The extent of surgical resection (EOR) has been recorded as conditioning outcome in glioblastoma multiforme (GBM) patients but no significant improvements were recorded in survival. The study aimed to evaluate the impact of EOR on survival, investigating the role of fluid-attenuated inversion recovery (FLAIR) abnormalities removal. 282 newly diagnosed GBM patients were treated with surgery followed by concurrent and adjuvant chemo-radiotherapy. The EOR was defined as: SUPr, in case of resection amounting to 100% of enhanced and FLAIR areas; gross total (GTR) in case of resection between 90 and 100% of enhanced areas with variable amount of FLAIR abnormalities; sub-total (STR), between 10 and 89%; biopsy (B) <10%...
July 8, 2017: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/28669011/extent-of-resection-and-carmustine-wafer-implantation-safely-improve-survival-in-patients-with-a-newly-diagnosed-glioblastoma-a-single-center-experience-of-the-current-practice
#3
Alexandre Roux, Sophie Peeters, Marc Zanello, Rabih Bou Nassif, Georges Abi Lahoud, Edouard Dezamis, Eduardo Parraga, Emmanuelle Lechapt-Zalcmann, Frédéric Dhermain, Sarah Dumont, Guillaume Louvel, Fabrice Chretien, Xavier Sauvageon, Bertrand Devaux, Catherine Oppenheim, Johan Pallud
For newly diagnosed glioblastomas treated with resection in association with the standard combined chemoradiotherapy, the impact of Carmustine wafer implantation remains debated regarding postoperative infections, quality of life, and feasibility of adjuvant oncological treatments. To assess together safety, tolerance and efficacy of Carmustine wafer implantation and of extent of resection for glioblastoma patients in real-life experience. Observational retrospective monocentric study including 340 consecutive adult patients with a newly diagnosed supratentorial glioblastoma who underwent surgical resection with (n = 123) or without (n = 217) Carmustine wafer implantation as first-line oncological treatment...
July 1, 2017: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/28645590/endoscopic-supracerebellar-transtentorial-approach-to-the-atrium-of-the-lateral-ventricle-preliminary-surgical-and-optical-considerations
#4
Tao Xie, Linjun Zhou, Xiaobiao Zhang, Wei Sun, Hailin Ding, Tengfei Liu, Ye Gu, Chongjing Sun, Fan Hu, Wei Zhu
OBJECTIVE: To report the operative techniques of the endoscopic supracerebellar transtentorial approach (ESTA) to the atrium of the lateral ventricle, especially focusing on the role of the endoscope and analyzing optically related issues. METHODS: A retrospective data review was performed on five patients with lesions in the atrium of the lateral ventricle undergoing the ESTA. The patients were positioned in the three-quarters prone position, and a paramidline linear incision was used...
June 20, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28440461/the-role-of-mir-451-in-the-switching-between-proliferation-and-migration-in-malignant-glioma-cells-ampk-signaling-mtor-modulation-and-rac1-activation-required
#5
Kai Zhao, Leilei Wang, Tao Li, Meng Zhu, Chen Zhang, Lei Chen, Pengfei Zhao, Hua Zhou, Shengping Yu, Xuejun Yang
Glioblastoma multiforme (GBM), WHO grade IV astrocytoma, is the most common primary neoplasm of the central nervous system (CNS) and has the highest malignancy and mortality rates. The invasive nature of GBM complicates surgical resection and restricts chemotherapeutic access, contributing to poor patient prognosis. The migration of tumor cells is closely related to the tumor cell proliferation. The acquisition of migratory capability, in addition to intracellular factors, is proposed to be a crucial mechanism during the progression of invasion...
April 21, 2017: International Journal of Oncology
https://www.readbyqxmd.com/read/28236180/supraorbital-subfrontal-trans-laminar-endoscope-assisted-approach-for-tumors-of-the-posterior-third-ventricle
#6
Maurizio Iacoangeli, Roberto Colasanti, Domenic Esposito, Alessandro Di Rienzo, Lucia di Somma, Mauro Dobran, Maurizio Gladi, Massimo Scerrati
BACKGROUND: Different surgical approaches have been developed for dealing with third ventricle lesions, all aimed at obtaining a safe removal minimizing brain manipulation. The supraorbital subfrontal trans-lamina terminalis route, commonly employed only for the anterior third ventricle, could represent, in selected cases with endoscopic assistance, an alternative approach to posterior third ventricular lesions. METHODS: Seven patients underwent a supraorbital subfrontal trans-laminar endoscope-assisted approach to posterior third ventricle tumors (two craniopharyngiomas, one papillary tumor of the pineal region, one pineocytoma, two neurocytomas, one glioblastoma)...
February 24, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/28169411/-factors-related-with-post-surgical-complications-in-elderly-patients-with-glioblastoma-multiforme
#7
M Martin-Risco, V Rodrigo-Paradells, S Olivera-Gonzalez, C M Del Rio-Perez, L Bances-Florez, J B Calatayud-Perez, F J Villagrasa-Compaired
INTRODUCTION: Glioblastoma multiforme is the most frequent malignant tumour of the central nervous system, and its incidence reaches 80% in those over 50 years of age. Life expectancy has increased in the population in recent times and an analysis of the post-surgical complications affecting elderly patients is of great importance for a correct surgical indication. AIMS: To analyse the factors related with post-surgical complications in elderly patients. PATIENTS AND METHODS: A sample of 88 patients diagnosed with glioblastoma multiforme between 31 and 78 years of age was analysed retrospectively...
February 16, 2017: Revista de Neurologia
https://www.readbyqxmd.com/read/28005261/results-of-a-multicenter-survey-showing-interindividual-variability-among-neurosurgeons-when-deciding-on-the-radicality-of-surgical-resection-in-glioblastoma-highlight-the-need-for-more-objective-guidelines
#8
J Capellades, P Teixidor, G Villalba, C Hostalot, G Plans, R Armengol, S Medrano, A Estival, R Luque, S Gonzalez, M Gil-Gil, S Villa, J Sepulveda, J J García-Mosquera, C Balana
PURPOSE: We assessed agreement among neurosurgeons on surgical approaches to individual glioblastoma patients and between their approach and those recommended by the topographical staging system described by Shinoda. METHODS: Five neurosurgeons were provided with pre-surgical MRIs of 76 patients. They selected the surgical approach [biopsy, partial resection, or gross total resection (GTR)] that they would recommend for each patient. They were blinded to each other's response and they were told that patients were younger than 50 years old and without symptoms...
June 2017: Clinical & Translational Oncology
https://www.readbyqxmd.com/read/27972425/in-hospital-mortality-and-complications-following-surgical-resection-of-glioblastoma
#9
P Chevalier, C van Gils, M Lamotte
No abstract text is available yet for this article.
November 2016: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/27690658/laser-interstitial-thermal-therapy-followed-by-minimal-access-transsulcal-resection-for-the-treatment-of-large-and-difficult-to-access-brain-tumors
#10
James Wright, Jessey Chugh, Christina Huang Wright, Fernando Alonso, Alia Hdeib, Haley Gittleman, Jill Barnholtz-Sloan, Andrew E Sloan
OBJECTIVE Laser interstitial thermal therapy (LITT), sometimes referred to as "stereotactic laser ablation," has demonstrated utility in a subset of high-risk surgical patients with difficult to access (DTA) intracranial neoplasms. However, the treatment of tumors larger than 10 cm(3) is associated with suboptimal outcomes and morbidity. This may limit the utility of LITT in dealing with precisely those large or deep tumors that are most difficult to treat with conventional approaches. Recently, several groups have reported on minimally invasive transsulcal approaches utilizing tubular retracting systems...
October 2016: Neurosurgical Focus
https://www.readbyqxmd.com/read/27668386/glioblastoma-overview-of-disease-and-treatment
#11
Mary Elizabeth Davis
BACKGROUND: Glioblastoma (GBM) is the most common and aggressive malignant brain tumor in adults. Current treatment options at diagnosis are multimodal and include surgical resection, radiation, and chemotherapy. Significant advances in the understanding of the molecular pathology of GBM and associated cell signaling pathways have opened opportunities for new therapies for recurrent and newly diagnosed disease. Innovative treatments, such as tumor-treating fields (TTFields) and immunotherapy, give hope for enhanced survival...
October 1, 2016: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/27643918/intraoperative-probe-based-confocal-laser-endomicroscopy-in-surgery-and-stereotactic-biopsy-of-low-grade-and-high-grade-gliomas-a-feasibility-study-in-humans
#12
Vladislav Pavlov, David Meyronet, Vincent Meyer-Bisch, Xavier Armoiry, Brian Pikul, Chloé Dumot, Pierre-Aurelien Beuriat, Francesco Signorelli, Jacques Guyotat
BACKGROUND: The management of gliomas is based on precise histologic diagnosis. The tumor tissue can be obtained during open surgery or via stereotactic biopsy. Intraoperative tissue imaging could substantially improve biopsy precision and, ultimately, the extent of resection. OBJECTIVE: To show the feasibility of intraoperative in vivo probe-based confocal laser endomicroscopy (pCLE) in surgery and biopsy of gliomas. METHODS: In our prospective observational study, 9 adult patients were enrolled between September 2014 and January 2015...
October 2016: Neurosurgery
https://www.readbyqxmd.com/read/27400094/fully-endoscopic-resection-of-intra-axial-brain-lesions-using-neuronavigated-pediatric-anoscope
#13
Murat Kutlay, Cahit Kural, Ilker Solmaz, Ozkan Tehli, Caglar Temiz, Mehmet Daneyemez, Yusuf Izci
AIM: To present a new simple disposable tubular retractor which provides fully endoscopic resections of the intraaxial brain lesions. MATERIAL AND METHODS: A total of 13 patients underwent surgical resection of an intraaxial brain lesion larger than 3 cm with a fully endoscopic approach using the navigation-guided pediatric anoscope. The anoscope was adapted to serve as a tubular retractor. All lesions were resected under endoscopic visualization and navigation guidance...
2016: Turkish Neurosurgery
https://www.readbyqxmd.com/read/27337238/parieto-occipital-interhemispheric-precuneal-approach-to-the-lesions-of-the-atrium-experience-with-66-patients
#14
Murat Geyik, Ibrahim Erkutlu, Mehmet Alptekin, Inan Gezgin, Ayşe Mizrak, Serhat Pusat, Abdulvahap Gok
AIM: The atrium (trigone) is the most common site for intraventricular lesions. The parieto-occipital interhemispheric precuneal approach (POIPA) is one of the particular ways to reach these lesions. The aim of this study was to draw specific attention to the surgical difficulties of these lesions and to present our experience with this operative approach. MATERIAL AND METHODS: Sixty-six patients with lesions located in the atrium of the lateral ventricles underwent surgical treatment in our institution using POIPA over a 13-year period...
2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/27091344/de-novo-glioblastoma-in-the-territory-of-a-recent-middle-cerebral-artery-infarction-and-a-residual-meningioma-pathogenesis-revisited
#15
Waseem Yaghmour, Maher E Kurdi, Saleh S Baeesa
BACKGROUND: The pathogenesis of glioblastoma is complex, and the implicated molecular mechanisms are yet to be understood. There are scattered reports describing a possible relationship between meningioma and glioblastoma and more rarely a relationship between infarction and glioblastoma. CASE PRESENTATION: We are reporting a 32-year-old male who developed left middle cerebral artery (MCA) infarction as a surgical complication for sphenoid meningioma. He developed recurrent symptoms 4 months later due to development of a glioblastoma adjacent to both the territory of the prior MCA infarct and the residual meningioma...
April 18, 2016: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27013078/falsely-low-values-of-oxygen-saturation-measured-by-pulse-oximetry-in-a-boy-treated-with-chinese-herb-tea
#16
Agnes S Meidert, Alexander Lang, Georg Hennig, Patricia Bernasconi, Aurelia Peraud, Josef Briegel, Tanija K Hüttl
An 8-year-old boy suffering from progressive glioblastoma was scheduled for neurosurgery. Prior to induction of anaesthesia pulse oximetry measured 64 % saturation of oxygen (SpO2). Arterial blood gas analysis revealed normal oxygen saturation and normal oxygen partial pressure. After having ruled out technical problems of pulse oximetry the neurosurgical procedure was halted. Meticulous examination of the child's history and medication did not explain a possible interaction of drugs with pulse oximetry. A Chinese herb tea had been given to the child, but was then stopped on the day of admission...
March 25, 2016: Journal of Clinical Monitoring and Computing
https://www.readbyqxmd.com/read/26926064/versatile-utilization-of-real-time-intraoperative-contrast-enhanced-ultrasound-in-cranial-neurosurgery-technical-note-and-retrospective-case-series
#17
Ilya Lekht, Noah Brauner, Joshua Bakhsheshian, Ki-Eun Chang, Mittul Gulati, Mark S Shiroishi, Edward G Grant, Eisha Christian, Gabriel Zada
OBJECTIVE: Intraoperative contrast-enhanced ultrasound (iCEUS) offers dynamic imaging and provides functional data in real time. However, no standardized protocols or validated quantitative data exist to guide its routine use in neurosurgery. The authors aimed to provide further clinical data on the versatile application of iCEUS through a technical note and illustrative case series. METHODS: Five patients undergoing craniotomies for suspected tumors were included...
March 2016: Neurosurgical Focus
https://www.readbyqxmd.com/read/26791930/delaying-standard-combined-chemoradiotherapy-after-surgical-resection-does-not-impact-survival-in-newly-diagnosed-glioblastoma-patients
#18
MULTICENTER STUDY
Guillaume Louvel, Philippe Metellus, Georges Noel, Sophie Peeters, Jacques Guyotat, Julien Duntze, Pierre-Jean Le Reste, Phong Dam Hieu, Thierry Faillot, Fabien Litre, Nicolas Desse, Antoine Petit, Evelyne Emery, Jimmy Voirin, Johann Peltier, François Caire, Jean-Rodolphe Vignes, Jean-Luc Barat, Olivier Langlois, Philippe Menei, Sarah N Dumont, Marc Zanello, Edouard Dezamis, Frédéric Dhermain, Johan Pallud
BACKGROUND: To assess the influence of the time interval between surgical resection and standard combined chemoradiotherapy on survival in newly diagnosed and homogeneously treated (surgical resection plus standard combined chemoradiotherapy) glioblastoma patients; while controlling confounding factors (extent of resection, carmustine wafer implantation, functional status, neurological deficit, and postoperative complications). METHODS: From 2005 to 2011, 692 adult patients (434 men; mean of 57...
January 2016: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/26775233/frailty-in-geriatric-glioblastoma-patients-a-predictor-of-operative-morbidity-and-outcome
#19
Michael Cloney, Randy D'Amico, Jordan Lebovic, Matthew Nazarian, Brad E Zacharia, Michael B Sisti, Jeffrey N Bruce, Guy M McKhann, Fabio M Iwamoto, Adam M Sonabend
BACKGROUND: Frailty is an emerging means of assessing overall health status and guiding management for geriatric patients. Frailty is associated with outcomes for many surgical indications in this age group. While half of all glioblastoma patients are 65 years old or older, frailty has not been examined in relation to surgery for glioblastoma. METHODS: We performed a retrospective study of patients age 65 years and older with pathologically confirmed glioblastoma at Columbia Presbyterian Hospital from 2000 to 2012; 319 patients were identified, 243 of whom underwent craniotomy for lobar lesions...
May 2016: World Neurosurgery
https://www.readbyqxmd.com/read/26621412/predicting-functional-impairment-in-brain-tumor-surgery-the-big-five-and-the-milan-complexity-scale
#20
Paolo Ferroli, Morgan Broggi, Silvia Schiavolin, Francesco Acerbi, Valentina Bettamio, Dario Caldiroli, Alberto Cusin, Emanuele La Corte, Matilde Leonardi, Alberto Raggi, Marco Schiariti, Sergio Visintini, Angelo Franzini, Giovanni Broggi
OBJECT The Milan Complexity Scale-a new practical grading scale designed to estimate the risk of neurological clinical worsening after performing surgery for tumor removal-is presented. METHODS A retrospective study was conducted on all elective consecutive surgical procedures for tumor resection between January 2012 and December 2014 at the Second Division of Neurosurgery at Fondazione IRCCS Istituto Neurologico Carlo Besta of Milan. A prospective database dedicated to reporting complications and all clinical and radiological data was retrospectively reviewed...
December 2015: Neurosurgical Focus
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