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https://www.readbyqxmd.com/read/29778929/anxiety-sensitivity-in-the-association-between-posttraumatic-stress-and-substance-use-disorders-a-systematic-review
#1
REVIEW
Anka A Vujanovic, Samantha G Farris, Brooke A Bartlett, Robert C Lyons, Moira Haller, Peter J Colvonen, Sonya B Norman
Posttraumatic stress disorder (PTSD) and substance use disorders (SUD) are complex psychiatric conditions that commonly co-occur. No evidence-based, "gold standard" treatments for PTSD/SUD comorbidity are currently available. Thus, it is imperative to better understand cognitive-affective mechanisms, targetable via cognitive-behavioral intervention (i.e., malleable), that may be related to both disorders in order to improve the theory and treatment of PTSD/SUD. Anxiety sensitivity is a malleable cognitive-affective factor with relevance to both PTSD and SUD...
May 17, 2018: Clinical Psychology Review
https://www.readbyqxmd.com/read/29748747/use-of-guideline-recommended-treatments-for-ptsd-among-community-based-providers-in-texas-and-vermont-implications-for-the-veterans-choice-program
#2
Erin P Finley, Michael Mader, Elizabeth K Haro, Polly H Noël, Nancy Bernardy, Craig S Rosen, Mary Bollinger, Hector A Garcia, Kathleen Sherrieb, Mary Jo V Pugh
Implementation of the Veterans Choice Program (VCP) allows Veterans to receive care paid for by the Department of Veterans Affairs (VA) in community settings. However, the quality of that care is unknown, particularly for complex conditions such as posttraumatic stress disorder (PTSD). A cross-sectional survey was conducted of 668 community primary care and mental health providers in Texas and Vermont to describe use of guideline-recommended treatments (GRTs) for PTSD. Relatively, few providers reported using guideline-recommended psychotherapy or prescribing practices...
May 10, 2018: Journal of Behavioral Health Services & Research
https://www.readbyqxmd.com/read/29738952/changing-patterns-in-the-prevalence-of-posttraumatic-stress-disorder-major-depressive-episode-and-generalized-anxiety-disorder-over-24-months-following-a-road-traffic-crash-results-from-the-uq-support-study
#3
Justin Kenardy, Shannon L Edmed, Swati Shourie, Jacelle Warren, Anna Crothers, Erin A Brown, Cate M Cameron, Michelle Heron-Delaney
OBJECTIVE: To examine the prevalence and changing patterns of PTSD, major depressive episode (MDE), and generalized anxiety disorder (GAD) in adult claimants who sustained a non-catastrophic injury in a road traffic crash (RTC) in Queensland, Australia. METHOD: Participants (N = 284) were assessed at approximately 6, 12, and 24 months post-RTC using the composite international diagnostic interview (CIDI) modules for PTSD, and CIDI-short form for MDE, and GAD...
April 21, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29736064/psychiatric-comorbidities-in-acute-coronary-syndromes-six-month-follow-up-study
#4
D Ramya Shruthi, S Sunil Kumar, Nagaraj Desai, Rajesh Raman, T S Sathyanarayana Rao
Introduction: Acute coronary syndrome (ACS) caused by coronary atherosclerosis include ST-segment elevation myocardial infarction (STEMI), non-STEMI, and unstable angina. The relation between psychiatric disorders and coronary artery disease is a complex one which includes the effect of the psychosocial factors on heart and vice versa. Point prevalence studies have been reported, but there is paucity of follow-up studies from India. Materials and Methods: The study is a follow-up evaluation at discharge of 248 consecutive patients presented with ACS at JSS Hospital, Mysuru, Karnataka, over a period of 6 months to assess the psychiatric comorbidities...
January 2018: Indian Journal of Psychiatry
https://www.readbyqxmd.com/read/29734226/functional-neuroanatomy-of-emotion-and-its-regulation-in-ptsd
#5
Jacklynn M Fitzgerald, Julia A DiGangi, K Luan Phan
Posttraumatic stress disorder (PTSD) is a devastating disorder, linked to profound mental, physical, occupational, and functional impairment. In addition, it is a highly complex disorder, characterized by symptom heterogeneity across multiple domains. Nevertheless, emotion dysregulation arising from the exaggerated response to threat or from the inability to regulate negative emotional states plays a defining role in the pathophysiology of PTSD. In order to improve our understanding of how emotion dysregulation manifests in this illness, functional neuroimaging research over the past 20 years provides great insight into underlying neuroanatomy of each component of emotion dysregulation in the context of PTSD...
May 2018: Harvard Review of Psychiatry
https://www.readbyqxmd.com/read/29707169/testing-competing-factor-models-of-the-latent-structure-of-post-traumatic-stress-disorder-and-complex-post-traumatic-stress-disorder-according-to-icd-11
#6
Siobhan Murphy, Ask Elklit, Sarah Dokkedahl, Mark Shevlin
With the publication of the International Statistical Classification of Diseases and Related Health Problems, 11th edition (ICD-11) due for release in 2018, a number of studies have assessed the factorial validity of the proposed post-traumatic stress disorder (PTSD) and complex (CPTSD) diagnostic criteria and whether the disorders are correlated but distinct constructs. As the specific nature of CPTSD symptoms has yet to be firmly established, this study aimed to examine the dimension of affect dysregulation as two separate constructs representing hyper-activation and hypo-activation...
2018: European Journal of Psychotraumatology
https://www.readbyqxmd.com/read/29695993/the-efficacy-of-eye-movement-desensitization-and-reprocessing-in-children-and-adults-who-have-experienced-complex-childhood-trauma-a-systematic-review-of-randomized-controlled-trials
#7
Runsen Chen, Amy Gillespie, Yanhui Zhao, Yingjun Xi, Yanping Ren, Loyola McLean
Background: Survivors of complex childhood trauma (CT) such as sexual abuse show poorer outcomes compared to single event trauma survivors. A growing number of studies investigate Eye Movement Desensitization and Reprocessing (EMDR) treatment for posttraumatic stress disorder (PTSD), but no systematic reviews have focused on EMDR treatment for CT as an intervention for both adults and children. This study therefore systematically reviewed all randomized controlled trials (RCTs) evaluating the effect of EMDR on PTSD symptoms in adults and children exposed to CT...
2018: Frontiers in Psychology
https://www.readbyqxmd.com/read/29677606/5-hz-repetitive-transcranial-magnetic-stimulation-for-posttraumatic-stress-disorder-comorbid-with-major-depressive-disorder
#8
Linda L Carpenter, Christine Conelea, Audrey R Tyrka, Emma S Welch, Benjamin D Greenberg, Lawrence H Price, Matthew Niedzwiecki, Agustin G Yip, Jennifer Barnes, Noah S Philip
BACKGROUND: Standard clinical protocols for repetitive transcranial magnetic stimulation (rTMS) for major depressive disorder (MDD) apply 10 Hz pulses over left prefrontal cortex, yet little is known about the effects of rTMS in more diagnostically complex depressed patients. OBJECTIVE/HYPOTHESIS: Posttraumatic stress disorder (PTSD) is commonly comorbid with MDD, and while rTMS has been shown to alleviate PTSD symptoms in preliminary studies, ideal parameters remain unclear...
April 5, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29674970/hypothesis-the-psychedelic-ayahuasca-heals-traumatic-memories-via-a-sigma-1-receptor-mediated-epigenetic-mnemonic-process
#9
Antonio Inserra
Ayahuasca ingestion modulates brain activity, neurotransmission, gene expression and epigenetic regulation. N,N -Dimethyltryptamine (DMT, one of the alkaloids in Ayahuasca) activates sigma 1 receptor (SIGMAR1) and others. SIGMAR1 is a multi-faceted stress-responsive receptor which promotes cell survival, neuroprotection, neuroplasticity, and neuroimmunomodulation. Simultaneously, monoamine oxidase inhibitors (MAOIs) also present in Ayahuasca prevent the degradation of DMT. One peculiarity of SIGMAR1 activation and MAOI activity is the reversal of mnemonic deficits in pre-clinical models...
2018: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29669363/couples-facing-the-birth-of-a-newborn-with-a-congenital-anomaly-ptsd-symptoms-in-the-first-year
#10
Francesca Bevilacqua, Francesco Morini, Antonio Zaccara, Chiara De Marchis, Annabella Braguglia, Simonetta Gentile, Pietro Bagolan, Lucia Aite
OBJECTIVE:  The objective of this study was to assess the presence of posttraumatic stress disorder (PTSD) symptoms in parental couples of newborn requiring early surgery at 6 and 12 months after birth. STUDY DESIGN:  A longitudinal study was set up from January 2014 to June 2015. As a measure of PTSD, we used the Italian version of the Impact of Event Scale-Revised (IES-R). RESULTS:  Thirty-four couples form the object of the study...
April 18, 2018: American Journal of Perinatology
https://www.readbyqxmd.com/read/29655375/association-between-traumatic-stress-load-psychopathology-and-cognition-in-the-philadelphia-neurodevelopmental-cohort
#11
Ran Barzilay, Monica E Calkins, Tyler M Moore, Daniel H Wolf, Theodore D Satterthwaite, J Cobb Scott, Jason D Jones, Tami D Benton, Ruben C Gur, Raquel E Gur
BACKGROUND: Traumatic stressors during childhood and adolescence are associated with psychopathology, mostly studied in the context of post-traumatic stress disorder (PTSD) and depression. We investigated broader associations of traumatic stress exposure with psychopathology and cognition in a youth community sample. METHODS: The Philadelphia Neurodevelopmental Cohort (N = 9498) is an investigation of clinical and neurobehavioral phenotypes in a diverse (56% Caucasian, 33% African American, 11% other) US youth community population (aged 8-21)...
April 15, 2018: Psychological Medicine
https://www.readbyqxmd.com/read/29649912/post-combat-adaptation-improving-social-support-and-reaching-constructive-growth
#12
L Y Saltzman, R Pat-Horenczyk, M Lombe, A Weltman, Y Ziv, T McNamara, D Takeuchi, D Brom
BACKGROUND AND OBJECTIVES: Posttraumatic stress disorder, a commonly researched mental health outcome associated with trauma, does not develop in the majority of survivors. More common trajectories of adaptation include resilience, and posttraumatic growth (PTG). The objectives of the current study were to: (1) describe posttrauma adaptation profiles in a sample of Israeli male military veterans (N = 448); and (2) to explore the protective factors that promote constructive PTG within two profiles of posttrauma adaptation...
April 12, 2018: Anxiety, Stress, and Coping
https://www.readbyqxmd.com/read/29628334/consolidative-mechanisms-of-emotional-processing-in-rem-sleep-and-ptsd
#13
REVIEW
Anthony L A Murkar, Joseph De Koninck
Research suggests sleep plays a role in the consolidation of recently acquired memories for long-term storage. rapid eye movement (REM) sleep has been shown to play a complex role in emotional-memory processing, and may be involved in subsequent waking-day emotional reactivity and amygdala responsivity. Interaction of the hippocampus and basolateral amygdala with the medial-prefrontal cortex is associated with sleep-dependent learning and emotional memory processing. REM is also implicated in post-traumatic stress disorder (PTSD), which is characterized by sleep disturbance, heightened reactivity to fearful stimuli, and nightmares...
March 15, 2018: Sleep Medicine Reviews
https://www.readbyqxmd.com/read/29621820/-mental-disorders-specifically-associated-with-stress-in-the-upcoming-icd-11-an-overview
#14
Mareike Augsburger, Andreas Maercker
The release of upcoming ICD-11 results in important changes to the classification of stress-related mental disorders. With the aim to improve clinical utility there is a new organizational structure for the different disorders as they are now categorized by the response to specific types of stressors. These range from reactions based on the experience of psychosocial strains (adjustment disorder), to grief reactions with a need for treatment (prolonged grief disorder) and reactions after exposure to traumatic events (posttraumatic stress disorder), also with more complex clinical picture (complex posttraumatic stress disorder)...
March 2018: Fortschritte der Neurologie-Psychiatrie
https://www.readbyqxmd.com/read/29601372/illness-uncertainty-and-posttraumatic-stress-in-young-adults-with-congenital-heart-disease
#15
Patricia Moreland, Sheila Judge Santacroce
BACKGROUND: Young adults with congenital heart disease (CHD) are at risk for chronic illness uncertainty in 4 domains: ambiguity about the state of their illness; lack of information about the disease, its treatment, and comorbidities; complexity of the healthcare system and relationship with healthcare providers; and unpredictability of the illness course and outcome. Chronic uncertainty has been associated with posttraumatic stress symptoms (PTSS) and posttraumatic stress disorder (PTSD)...
March 29, 2018: Journal of Cardiovascular Nursing
https://www.readbyqxmd.com/read/29578033/propranolol-produces-short-term-facilitation-of-extinction-in-a-rabbit-model-of-post-traumatic-stress-disorder
#16
Lauren B Burhans, Carrie A Smith-Bell, Bernard G Schreurs
Post-traumatic stress disorder (PTSD) is a learning-based anxiety disorder with significant public health challenges due to difficulties in treating the complex, multiple symptomology. We have developed an animal model of PTSD, based on Pavlovian eyeblink conditioning in rabbits, that addresses two key features: conditioned responses (CRs) to cues associated with an aversive event and a form of conditioned hyperarousal referred to as conditioning-specific reflex modification (CRM). We have found previously that unpaired extinction is ideal for reducing both CRs and CRM simultaneously and shows sensitivity to systemic serotonergic and glutamatergic manipulations...
March 22, 2018: Neuropharmacology
https://www.readbyqxmd.com/read/29577450/posttraumatic-stress-disorder-and-complex-posttraumatic-stress-disorder-in-dsm-5-and-icd-11-clinical-and-behavioral-correlates
#17
Philip Hyland, Mark Shevlin, Claire Fyvie, Thanos Karatzias
The American Psychiatric Association and the World Health Organization provide distinct trauma-based diagnoses in the fifth edition of the Diagnostic and Statistical Manual (DSM-5), and the forthcoming 11th version of the International Classification of Diseases (ICD-11), respectively. The DSM-5 conceptualizes posttraumatic stress disorder (PTSD) as a single, broad diagnosis, whereas the ICD-11 proposes two "sibling" disorders: PTSD and complex PTSD (CPTSD). The objectives of the current study were to: (a) compare prevalence rates of PTSD/CPTSD based on each diagnostic system; (b) identify clinical and behavioral variables that distinguish ICD-11 CPTSD and PTSD diagnoses; and (c) examine the diagnostic associations for ICD-11 CPTSD and DSM-5 PTSD...
March 25, 2018: Journal of Traumatic Stress
https://www.readbyqxmd.com/read/29568727/complex-posttraumatic-stress-disorder-the-need-to-consolidate-a-distinct-clinical-syndrome-or-to-reevaluate-features-of-psychiatric-disorders-following-interpersonal-trauma
#18
REVIEW
Evangelia Giourou, Maria Skokou, Stuart P Andrew, Konstantina Alexopoulou, Philippos Gourzis, Eleni Jelastopulu
Complex posttraumatic stress disorder (Complex PTSD) has been recently proposed as a distinct clinical entity in the WHO International Classification of Diseases, 11th version, due to be published, two decades after its first initiation. It is described as an enhanced version of the current definition of PTSD, with clinical features of PTSD plus three additional clusters of symptoms namely emotional dysregulation, negative self-cognitions and interpersonal hardship, thus resembling the clinical features commonly encountered in borderline personality disorder (BPD)...
March 22, 2018: World Journal of Psychiatry
https://www.readbyqxmd.com/read/29565758/the-disorder-specific-psychological-impairment-in-complex-ptsd-a-flawed-working-model-for-restoration-of-trust
#19
Andreas Laddis
This article methodically gathers concepts and findings from related disciplines to propose that there is a fundamental, disorder-specific psychological impairment, which defines Complex Posttraumatic Stress Disorder (PTSD) as etiologically different from simple PTSD. This impairment is a flawed working model for restoration of trust when one partner fears betrayal. This working model is legacy of childhood relationships with manipulative caretakers who kept the child powerless to test the trustworthiness of their reasons to break promises and to fail the child's expectations...
March 22, 2018: Journal of Trauma & Dissociation
https://www.readbyqxmd.com/read/29558341/a-comparison-of-psychological-symptoms-in-survivors-of-sex-and-labor-trafficking
#20
E K Hopper, L D Gonzalez
Human trafficking is a form of interpersonal trauma that has significant mental health impacts on survivors. This study examined psychological symptoms in 131 survivors of sex and labor trafficking, including people trafficked into or within the U.S. High rates of depression (71%) and PTSD (61%) were identified. Two thirds of survivors also met criteria for multiple categories of Complex PTSD (C-PTSD), including affect dysregulation and impulsivity; alterations in attention and consciousness; changes in interpersonal relationships; revictimization; somatic dysregulation; and alterations in self-perception...
March 20, 2018: Behavioral Medicine
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