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https://www.readbyqxmd.com/read/28440900/phosphoglycerate-dehydrogenase-phgdh-deficiency-without-epilepsy-mimicking-primary-microcephaly
#1
Antoine Poli, Yoann Vial, Damien Haye, Sandrine Passemard, Manuel Schiff, Hala Nasser, Catherine Delanoe, Emma Cuadro, Rémi Kom, Narcisse Elanga, Anne Favre, Séverine Drunat, Alain Verloes
Phosphoglycerate dehydrogenase (PHGDH) deficiency (OMIM 256520) is a rare autosomal recessive disorder of serine synthesis, with mostly severe congenital microcephaly, caused by mutations in the PHGDH gene. Fourteen patients reported to date show severe, early onset, drug resistant epilepsy. In a cohort of patients referred for primary microcephaly, compound heterozygosity for two unreported variants in PHGDG was identified by exome sequencing in a pair of sibs who died aged 4.5 months and 4.5 years. They had severe neurological involvement with congenital microcephaly, disorganized EEG, and progressive spasticity, but never had seizures...
April 25, 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/28436690/a-comparison-of-the-nomological-networks-associated-with-forced-choice-and-likert-formats-of-the-narcissistic-personality-inventory
#2
Joshua D Miller, Brittany Gentile, Nathan T Carter, Michael Crowe, Brian J Hoffman, W Keith Campbell
The Narcissistic Personality Inventory (NPI) is one of the most popular measures of narcissism. However, its use of a forced-choice response set might negatively affect some of its psychometric properties. The purpose of this research was to compare a Likert version of the NPI, in which only the narcissistic response of each pair was given, to the original NPI, in 3 samples of participants (N = 1,109). To this end, we compared the nomological networks of the forced-choice and Likert formats of the NPI in relation to alternative measures of narcissism, narcissistic personality disorder, entitlement, self-esteem, general personality traits (reported by self and informants), interpersonal styles, and general pathological traits included in the DSM-5...
April 24, 2017: Journal of Personality Assessment
https://www.readbyqxmd.com/read/28435339/compulsive-exercise-links-risks-and-challenges-facedent
#3
REVIEW
Mia Beck Lichtenstein, Cecilie Juul Hinze, Bolette Emborg, Freja Thomsen, Simone Daugaard Hemmingsen
Compulsive exercise is a condition described since 1970s. It is characterized by a craving for physical training, resulting in uncontrollable excessive exercise behavior with harmful consequences, such as injuries and impaired social relations. It has not been accepted as a mental disorder in either International Classification of Diseases or Diagnostic and Statistical Manual of Mental Disorders. The aim of this literature review was to critically examine the research on links (comorbidity), risks (negative consequences), and challenges faced (problems in a treatment context)...
2017: Psychology Research and Behavior Management
https://www.readbyqxmd.com/read/28400320/classification-proposed-of-malignant-intraosseous-odontogenic-tumors-miot
#4
N Zwetyenga, E Broly, D Guillier, A Hallier, J Levasseur, V Moris
Malignant intraosseous odontogenic tumors (MIOT) of the jaws are very rare. The diagnosis is difficult. Clinical, paraclinical and histological diagnostic criteria, strict are well established. But the International Union Against Cancer (UICC) does not provide TNM classification that will allow harmonization of the treatment. Indeed, despite their location, they cannot be classified as primary tumors of the oral cavity because of their localization in the bone marrow, making them systematically classified as T4...
April 8, 2017: Journal of Stomatology, Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28386406/a-rare-case-of-emphysematous-pyelonephritis-in-a-renal-transplant-patient
#5
Dennis Narcisse, Manyoo Agarwal, Michael Hancock, Daniel Wells, Christopher Sands
Emphysematous pyelonephritis (EPN) is a rare life-threatening complication of a properly functioning renal allograft leading to potential graft loss and hemodialysis. Currently, no clear management guidelines exist in these clinically challenging immunosuppressed renal transplant recipients. We report a case of a 62-year-old woman who presented with class 4 EPN and was managed with intravenous antibiotics and nephrectomy at our medical center.
December 2016: Therapeutic Advances in Infectious Disease
https://www.readbyqxmd.com/read/28382846/revisiting-the-structure-of-the-short-dark-triad
#6
Björn N Persson, Petri J Kajonius, Danilo Garcia
In the past decade, extensive interest has been directed toward the Dark Triad (i.e., Machiavellianism, narcissism, and psychopathy), popularly assessed by the Short Dark Triad (SD3). Nevertheless, relatively little research has been conducted on the SD3's factor structure. We investigated the SD3's psychometric properties in three studies with three independent samples, using exploratory and confirmatory factor analyses ( N1 = 1,487; N2 = 17,740; N3 = 496). In all three studies, Machiavellianism and psychopathy items displayed large general factor loadings, and narcissism larger specific factor loadings...
April 1, 2017: Assessment
https://www.readbyqxmd.com/read/28355931/a-brief-measure-of-narcissism-among-female-juvenile-delinquents-and-community-youths
#7
Pedro Pechorro, João Maroco, James V Ray, Rui Abrunhosa Gonçalves, Cristina Nunes
Research on narcissism has a long tradition, but there is limited knowledge regarding its application among female youth, especially for forensic samples of incarcerated female youth. Drawing on 377 female adolescents (103 selected from forensic settings and 274 selected from school settings) from Portugal, the current study is the first to examine simultaneously the psychometric properties of a brief version of the Narcissistic Personality Inventory (NPI-13) among females drawn from incarcerated and community settings...
March 1, 2017: International Journal of Offender Therapy and Comparative Criminology
https://www.readbyqxmd.com/read/28355929/teasing-apart-overclaiming-overconfidence-and-socially-desirable-responding
#8
Doreen Bensch, Delroy L Paulhus, Lazar Stankov, Matthias Ziegler
Contamination with positivity bias is a potential problem in virtually all areas of psychological assessment. To determine the impact of positivity bias, one common approach is to embed special indicators within one's assessment battery. Such tools range from social desirability scales to overconfidence measures to the so-called overclaiming technique. Despite the large literature on these different approaches and underlying theoretical notions, little is known about the overall nomological network-in particular, the degree to which these constructs overlap...
March 1, 2017: Assessment
https://www.readbyqxmd.com/read/28346685/experience-of-shame-mediates-the-relationship-between-pathological-narcissism-and-suicidal-ideation-in-psychiatric-outpatients
#9
Nenad Jaksic, Darko Marcinko, Milena Skocic Hanzek, Blaz Rebernjak, John S Ogrodniczuk
OBJECTIVE: Pathological narcissism, described by 2 dysfunctional phenotypic forms-grandiosity and vulnerability-has often been connected to suicidal tendencies in theoretical and clinical literatures. Furthermore, shame proneness has been implicated as a key mechanism that links these 2 constructs. However, empirical evidence for the presumed relationship between pathological narcissism and suicidal tendencies is sparse, and no prior research has investigated the role of shame proneness in this relationship...
March 27, 2017: Journal of Clinical Psychology
https://www.readbyqxmd.com/read/28346115/the-malevolent-side-of-human-nature
#10
Peter Muris, Harald Merckelbach, Henry Otgaar, Ewout Meijer
The term dark triad refers to the constellation of narcissism, Machiavellianism, and psychopathy. Over the past few years, the concept has gained momentum, with many researchers assuming that the dark triad is a prominent antecedent of transgressive and norm-violating behavior. Our purpose in this meta-analytic review was to evaluate (a) interrelations among narcissism, Machiavellianism, and psychopathy; (b) gender differences in these traits; (c) how these traits are linked to normal personality factors; and (d) the psychosocial correlates of the dark triad...
March 2017: Perspectives on Psychological Science: a Journal of the Association for Psychological Science
https://www.readbyqxmd.com/read/28343147/ethical-ramifications-of-the-paolo-macchiarini-case
#11
Jaime A Teixeira da Silva
The Paolo Macchiarini case has several ethical ramifications. Professor Macchiarini, formerly of the Karolinska Institutet (KI), became famous for the tracheal surgeries he conducted between 2008 and 2014. His rapid rise to fame was followed by an almost equally rapid fall from grace as official reports, articles in newspapers and television programmes revealed several aspects related to misconduct in his curriculum vitae, professional practices and publishing-related activity. Formal misconduct reports issued by four KI co-workers in late 2014, then again in 2016, coupled with social scandals, including the tricking of a famous US television newscaster into a false marriage, a previous arrest in Italy for apparent bribery, and acute narcissism, all tainted Macchiarini's legend...
March 15, 2017: Indian Journal of Medical Ethics
https://www.readbyqxmd.com/read/28326048/developing-a-taxonomy-of-dark-triad-triggers-at-work-a-grounded-theory-study-protocol
#12
Annika Nübold, Josef Bader, Nera Bozin, Romil Depala, Helena Eidast, Elisabeth A Johannessen, Gerhard Prinz
In past years, research and corporate scandals have evidenced the destructive effects of the dark triad at work, consisting of narcissism (extreme self-centeredness), psychopathy (lack of empathy and remorse) and Machiavellianism (a sense of duplicity and manipulativeness). The dark triad dimensions have typically been conceptualized as stable personality traits, ignoring the accumulating evidence that momentary personality expressions - personality states - may change due to the characteristics of the situation...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28301969/the-internet-s-effect-on-personality-traits-an-important-casualty-of-the-internet-addiction-paradigm
#13
Elias Aboujaoude
Background and aims The "Internet addiction" paradigm has been criticized for several shortcomings, including inattention to specific online behaviors, not distinguishing the Internet from other media, insufficient focus on comorbidities, and definitions that do not take into account the constant access now possible. The paradigm's biggest casualty, however, may be that it has diverted attention away from subtle personality changes that seem to occur online, including in users who cannot be considered "addicted" under any definition...
March 1, 2017: Journal of Behavioral Addictions
https://www.readbyqxmd.com/read/28301765/controversies-in-narcissism
#14
Joshua D Miller, Donald R Lynam, Courtland S Hyatt, W Keith Campbell
There has been a surge in interest in and research on narcissism and narcissistic personality disorder (NPD). Despite or because of this increased attention, there are several areas of substantial debate that surround the construct, including descriptions of grandiose and vulnerable dimensions or variants, questions regarding the existence of a consensual description, central versus peripheral features of narcissism, distinctions between normal and pathological narcissism, possible etiological factors, the role of self-esteem narcissism, where narcissism should be studied, how it can be assessed, and its representation in diagnostic nosologies...
March 15, 2017: Annual Review of Clinical Psychology
https://www.readbyqxmd.com/read/28293674/monitoring-and-analysis-of-the-change-process-in-curriculum-mapping-compared-to-the-national-competency-based-learning-objective-catalogue-for-undergraduate-medical-education-nklm-at-four-medical-faculties-part-i-conducive-resources-and-structures
#15
Maria Lammerding-Koeppel, Marianne Giesler, Maryna Gornostayeva, Elisabeth Narciss, Annette Wosnik, Stephan Zipfel, Jan Griewatz, Olaf Fritze
Objective: After passing of the National Competency-based Learning Objectives Catalogue in Medicine (Nationaler Kompetenzbasierter Lernzielkatalog Medizin, [NKLM, retrieved on 22.03.2016]), the German medical faculties must take inventory and develop their curricula. NKLM contents are expected to be present, but not linked well or sensibly enough in locally grown curricula. Learning and examination formats must be reviewed for appropriateness and coverage of the competences. The necessary curricular transparency is best achieved by systematic curriculum mapping, combined with effective change management...
2017: GMS Journal for Medical Education
https://www.readbyqxmd.com/read/28293673/monitoring-and-analysis-of-the-change-process-in-curriculum-mapping-compared-to-the-national-competency-based-learning-objective-catalogue-for-undergraduate-medical-education-nklm-at-four-medical-faculties-part-ii-key-factors-for-motivating-the-faculty-during
#16
Maria Lammerding-Koeppel, Marianne Giesler, Maryna Gornostayeva, Elisabeth Narciss, Annette Wosnik, Stephan Zipfel, Jan Griewatz, Olaf Fritze
Objective: After adoption of the National Competency-based Learning Objectives Catalogue in Medicine [Nationaler Kompetenzbasierter Lernzielkatalog Medizin, NKLM], the German medical faculties are asked to test the learning obejctives recorded in it and evaluate them critically. The faculties require curricular transparency for competence-oriented transition of present curricula, which is best achieved by systematic curriculum mapping in comparison to the NKLM. Based on this inventory, curricula can be further developed target-oriented...
2017: GMS Journal for Medical Education
https://www.readbyqxmd.com/read/28263094/development-and-validation-of-the-treatment-attrition-retention-scale-for-personality-disorders
#17
Dominick Gamache, Claudia Savard, Sophie Lemelin, Evens Villeneuve
This study is an investigation of the psychometric properties of the Treatment Attrition-Retention Scale for Personality Disorders (TARS-PD), an instrument developed to identify patients with personality disorder (PD) at risk of early dropout from psychotherapy. In a first study, assessment files from 320 patients referred for PD evaluation at an outpatient clinic were examined to assess the instrument's inter-rater reliability, construct validity, and discriminant validity. Results showed that the global scale could be scored with excellent reliability...
March 6, 2017: Journal of Personality Disorders
https://www.readbyqxmd.com/read/28253006/duplicity-among-the-dark-triad-three-faces-of-deceit
#18
Daniel N Jones, Delroy L Paulhus
Although all 3 of the Dark Triad members are predisposed to engage in exploitative interpersonal behavior, their motivations and tactics vary. Here we explore their distinctive dynamics with 5 behavioral studies of dishonesty (total N = 1,750). All 3 traits predicted cheating on a coin-flipping task when there was little risk of being caught (Study 1). Only psychopathy predicted cheating when punishment was a serious risk (Study 2). Machiavellian individuals also cheated under high risk-but only if they were ego-depleted (Study 3)...
March 2, 2017: Journal of Personality and Social Psychology
https://www.readbyqxmd.com/read/28252974/validation-of-the-narcissistic-admiration-and-rivalry-questionnaire-short-scale-narq-s-in-convenience-and-representative-samples
#19
Marius Leckelt, Eunike Wetzel, Tanja M Gerlach, Robert A Ackerman, Joshua D Miller, William J Chopik, Lars Penke, Katharina Geukes, Albrecht C P Küfner, Roos Hutteman, David Richter, Karl-Heinz Renner, Marc Allroggen, Courtney Brecheen, W Keith Campbell, Igor Grossmann, Mitja D Back
Due to increased empirical interest in narcissism across the social sciences, there is a need for inventories that can be administered quickly while also reliably measuring both the agentic and antagonistic aspects of grandiose narcissism. In this study, we sought to validate the factor structure, provide representative descriptive data and reliability estimates, assess the reliability across the trait spectrum, and examine the nomological network of the short version of the Narcissistic Admiration and Rivalry Questionnaire (NARQ-S; Back et al...
March 2, 2017: Psychological Assessment
https://www.readbyqxmd.com/read/28208077/personality-dimensions-in-schizophrenia-a-family-study
#20
Vina M Goghari
Studies have demonstrated that personality traits differ in schizophrenia patients and family members compared to controls, suggesting familial risk. This study evaluated personality traits in a family study of schizophrenia, as well as the relationship between personality traits and symptoms and social functioning in schizophrenia patients. Thirty-two schizophrenia patients, 28 adult non-psychotic relatives, and 27 community controls completed the Dimensional Assessment of Personality Pathology-Basic Questionnaire (DAPP-BQ)...
May 2017: Psychiatry Research
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