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https://www.readbyqxmd.com/read/28086924/treating-infants-with-frigg-linking-disease-aetiologies-medicinal-plant-use-and-care-seeking-behaviour-in-southern-morocco
#1
Irene Teixidor-Toneu, Gary J Martin, Rajindra K Puri, Ahmed Ouhammou, Julie A Hawkins
BACKGROUND: Although most Moroccans rely to some extent on traditional medicine, the practice of frigg to treat paediatric ailments by elderly women traditional healers known as ferraggat, has not yet been documented. We describe the role of these specialist healers, document the medicinal plants they use, and evaluate how and why their practice is changing. METHODS: Ethnomedicinal and ethnobotanical data were collected using semi-structured interviews and observations of medical encounters...
January 13, 2017: Journal of Ethnobiology and Ethnomedicine
https://www.readbyqxmd.com/read/28078240/effect-of-methanol-leaf-extract-of-dalbergia-saxatilis-hook-f-fabaceae-on-renal-function
#2
Fatima Ismail Hassan, Zezi Abdulkadir Umar, Danmalam Umar Habib, Yaro Abdullahi Hamza
OBJECTIVE: Dalbegia saxatilis (D.saxatilis) is used as a decoction in traditional medicine for ailments such as cough, small pox, skin lesions, bronchial ailments and toothache. This study is aimed at evaluating the toxic effect of methanol leaf extract of D.saxatilis on renal function. MATERIALS AND METHODS: Wistar rats of both sexes were divided into four groups of five: control animals (group 1) received distilled water 1 ml/kg while groups 2, 3 and 4 were given graded doses of the extract (250, 500 and 1000 mg/kg body weight, respectively) daily for 28 days...
November 2016: Avicenna Journal of Phytomedicine
https://www.readbyqxmd.com/read/28076651/controlled-release-of-chlorhexidine-from-a-mesoporous-silica-containing-macroporous-titanium-dental-implant-prevents-microbial-biofilm-formation
#3
K De Cremer, A Braem, E Gerits, K De Brucker, K Vandamme, J A Martens, J Michiels, J Vleugels, B P Cammue, K Thevissen
Roughened surfaces are increasingly being used for dental implant applications as the enlarged contact area improves bone cell anchorage, thereby facilitating osseointegration. However, the additional surface area also entails a higher risk for the development of biofilm associated infections, an etiologic factor for many dental ailments, including peri-implantitis. To overcome this problem, we designed a dental implant composed of a porous titanium-silica (Ti/SiO2) composite material and containing an internal reservoir that can be loaded with antimicrobial compounds...
January 11, 2017: European Cells & Materials
https://www.readbyqxmd.com/read/28073099/golden-root-a-wholesome-treat-of-immunity
#4
REVIEW
Kunjan Khanna, K P Mishra, Lilly Ganju, Shashi Bala Singh
Rhodiola is native to the high altitude regions of Asia, Europe and Northern Hemisphere. It has a long history of use as a medicinal plant in various ailments, boosting immunity, increasing energy and mental capacity. It is also known as "Adaptogen" to help the body to adapt and resist stress. The part of the plant, which is used for medicinal values, is rhizome, which is an underground stem. The rhizome contains mainly salidroside, rosin, rosavin and p-tyrosol. There are many studies, which have reported the effects of Rhodiola spp...
January 7, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28070467/social-support-and-resilience-among-patients-with-burn-injury-in-lahore-pakistan
#5
Ahmed Waqas, Sadiq Naveed, Mariam M Bhuiyan, Jawad Usman, Ahmed Inam-Ul-Haq, Sara S Cheema
INTRODUCTION: Social support and ego resiliency play a great role in maintaining the physical and mental health of patients with burn injuries. The present study has been designed to compare ego resiliency levels and the degree of social support in patients with a burn injury and their healthy counterparts. METHODS: This study was conducted in two teaching hospitals in Lahore, Pakistan from May 2015 to July 2015. A total of 80 burn patients presenting in outpatient departments of general surgery, plastic surgery, and burn centers of these hospitals were surveyed conveniently, and for comparison, 80 patients presenting in outpatient departments with minor ailments, for routine checkups or follow-ups were recruited...
November 8, 2016: Curēus
https://www.readbyqxmd.com/read/28068633/polyphenol-rich-ethanolic-extract-from-boerhavia-diffusa-l-mitigates-angiotensin-ii-induced-cardiac-hypertrophy-and-fibrosis-in-rats
#6
Prathapan A, Mathews V Varghese, Abhilash S, Salin Raj P, Anil K Mathew, Anupama Nair, R Harikumaran Nair, Raghu K G
Boerhavia diffusa is a renowned edible medicinal plant extensively used against different ailments including heart diseases in the traditional system of medicine in several countries. The present study aims to evaluate the therapeutic efficacy of ethanolic extract of Boerhavia diffusa (BDE) on cardiac hypertrophy and fibrosis induced by angiotensin II (Ang II) in male wistar rats and to identify the active components present in it. A substantial increase of hypertrophy markers such as cardiac mass index, concentration of ANP and BNP, cardiac injury markers like CK-MB, LDH and SGOT, has been observed in hypertrophied groups whereas BDE treatment attenuated these changes when compared to hypertrophied rats...
January 6, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28066109/cerebroprotective-activity-of-pentapetes-phoenicea-on-global-cerebral-ischemia-in-rats
#7
Koneru Naga Sravanthi, Nadendla Rama Rao
OBJECTIVES: The study was performed to evaluate the cerebroprotective activity of methanolic extract (ME) of Pentapetes phoenicea - a folk medicine used as anti-inflammatory and in central nervous system ailments. It has high phenolic and flavonoid contents including rutin. MATERIALS AND METHODS: Global cerebral ischemia was induced in male albino Wistar rats by temporary bilateral carotid artery occlusion (BCAO) for 30 min, followed by 4 h reperfusion. Groups of rats were pretreated for 10 days with 100, 200, and 400 mg/kg of ME of P...
November 2016: Indian Journal of Pharmacology
https://www.readbyqxmd.com/read/28065968/therapeutic-uses-of-pineapple-extracted-bromelain-in-surgical-care-a-review
#8
Zehra Abdul Muhammad, Tashfeen Ahmad
Bromelain is an extract obtained from the pineapple plant and is used as a traditional folk remedy for several ailments. In this review, a comprehensive electronic database search was carried out to compile available literature on therapeutic implications of bromelain. Pharmaceutical value of bromelain has been demonstrated in different surgical sub-specialties. Diverse biological processes like anti-inflammatory, anti-oedematous, analgesic, anti-thrombotic, exfoliation etc. are involved in bromelain's therapeutic actions, mediated through the kallikrein-kinin and arachidonic acid pathways as well as through effects on cell mediated immunity...
January 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28063919/proteomic-analysis-of-the-protective-effects-of-aqueous-bark-extract-of-terminalia-arjuna-roxb-on-isoproterenol-induced-cardiac-hypertrophy-in-rats
#9
Santosh Kumar, Md Jahangir Alam, Pankaj Prabhakar, Sayeed Ahmad, Subir K Maulik, Manish Sharma, Shyamal K Goswami
ETHNOPHARMACOLOGICAL RELEVANCE: Aqueous bark extract of Terminalia arjuna (TA) has been in use as an ethnomedicine for cardiovascular ailments in the Indian subcontinent for centuries. Studies using hemodynamic, ROS scavenging and anti-inflammatory parameters in animal models have shown its anti-atherogenic, hypotensive, inotropic, anti-inflammatory effects. However, details analysis on its effects on established molecular and cell biological markers are a prerequisite for its wider acceptance to the medical community...
January 4, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28061888/antibacterial-activities-of-the-methanol-extract-fractions-and-compounds-from-elaeophorbia-drupifera-thonn-stapf-euphorbiaceae
#10
Igor K Voukeng, Blaise K Nganou, Louis P Sandjo, Ilhami Celik, Veronique P Beng, Pierre Tane, Victor Kuete
BACKGROUND: Elaeophorbia drupifera (Thonn.) Stapf. (Euphorbiaceae) is used in Cameroonian folk medicine to treat several ailments including bacterial-related diseases such as skin infections. In this study, the methanol extract from the leaves (EDL), fractions (EDLa-d), sub-fractions EDLc1-7 and EDLc31-35 as well as isolated compounds were tested for their antimicrobial activities against a panel of Gram-negative and Gram-positive bacteria including multidrug resistant (MDR) phenotypes...
January 7, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28057074/how-acceptable-is-it-for-hiv-positive-african-caribbean-and-black-women-to-provide-breast-milk-fluid-samples-for-research-purposes
#11
L Kapiriri, W Tharao, M Muchenje, I M Khatundi, F Ongoiba
BACKGROUND: The African, Caribbean and Black communities have been found to be reluctant to participate in health research in North America. This is partly attributed to historical experiences as well as their cultural beliefs. Cultural beliefs about the uses of breast milk/fluids could further hinder the participation of African, Caribbean, and Black communities in research involving the collection of breast milk/fluids samples. METHODS: We conducted 17 in-depth interviews and three group interviews (n = 10) with HIV+ African, Caribbean and Black women living in Ontario, Canada to explore their cultural beliefs about breast milk/fluids and their acceptance of participating in research that involves the provision of breast fluid samples...
January 3, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28056498/bone-marrow-stem-cell-therapy-partially-ameliorates-pathological-consequences-in-livers-of-mice-expressing-mutant-human-%C3%AE-1-antitrypsin
#12
Prakash Baligar, Veena Kochat, Shailendra K Arindkar, Zaffar Equbal, Snehashish Mukherjee, Swati Patel, Perumal Nagarajan, Sujata Mohanty, Jeffrey H Teckman, Asok Mukhopadhyay
: Alpha1-antitrypsin deficiency (AATD) is a genetic disease, caused by mutation of the AAT gene. Accumulation of mutated AAT protein aggregates in hepatocytes leads to endoplasmic reticulum (ER) stress resulting in impairment of liver functions and in some cases hepatocellular carcinoma, whereas decline of AAT levels in sera is responsible for pulmonary emphysema. In critical cases of liver ailments, the only option for treatment is liver transplantation, whereas AAT replacement therapy is followed in case of emphysema...
January 5, 2017: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/28053893/bryophytes-hoard-of-remedies-an-ethno-medicinal-review
#13
REVIEW
Satish Chandra, Dinesh Chandra, Anupam Barh, Pankaj, Raj Kumar Pandey, Ishwar Prakash Sharma
Bryophytes are the second largest group of land plants after angiosperms. There is very less knowledge available about medicinal properties of these plants. Bryophytes are popular remedy among the tribal people of different parts of the world. Tribal people use these plants to cure various ailments in their daily lives. Bryophytes are used to cure hepatic disorders, skin diseases, cardiovascular diseases, used as antipyretic, antimicrobial, wound healing and many more other ailments by different tribal communities of Africa, America, Europe, Poland, Argentina, Australia, New Zealand, Turkey, Japan, Taiwan, Pakistan, China, Nepal and different parts of South, North and Eastern India...
January 2017: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/28052647/the-modulative-effects-of-microcurrent-electrical-nerve-stimulation-on-diabetic-mice
#14
Wen-Ching Huang, Wen-Chieh Chang, Yi-Ju Hsu, Chun-Feng Huang, Chi-Chang Huang, Cheng-Yan Kao, Che-Li Lin
Diabetes (one of non-communicable diseases) is serious due to its complications, such like, cardiovascular ailments, neuropathy, nephropathy, retinopathy, wound gangrene and sexual impotence. Diabetes and associated chronic conditions are rapidly emerging as major health problems. In clinical, there were different drugs for diabetes treatment on different mechanisms. However, there were limited studies on the efficacy of electric stimulations on diabetes therapeutic application. In current study, we try to evaluate the effect of microcurrent electrical nerve stimulator (MENS) on diabetes modulation as an alternative medicine...
28, 2017: Chinese Journal of Physiology
https://www.readbyqxmd.com/read/28049535/gaultheria-trichophylla-royle-a-source-of-minerals-and-biologically-active-molecules-its-antioxidant-and-anti-lipoxygenase-activities
#15
Fiaz Alam, Qazi Najam Us Saqib, Mohammad Ashraf
BACKGROUND: Gaultheria trichophylla (Royle) is used as food and for treating many ailments in folk medicine especially against inflammation. The purpose of this in vitro study was to evaluate the ability of extracts of G. trichophylla as anti-oxidant and anti-inflammatory agent and for its mineral contents. METHODS: Powdered plant material (100 g) was extracted with 100 ml each of methanol, chloroform, and n-hexane using soxhlet extractor. Antioxidant activity of methanol extract was assessed by DPPH radical scavenging and FRAP assays...
January 3, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28034659/toxins-and-pharmacologically-active-compounds-from-species-of-the-family-bufonidae-amphibia-anura
#16
REVIEW
Candelario Rodríguez, Louise Rollins-Smith, Roberto Ibáñez, Armando A Durant-Archibold, Marcelino Gutiérrez
ETHNOPHARMACOLOGICAL RELEVANCE: Among amphibians, 15 of the 47 species reported to be used in traditional medicines belong to the family Bufonidae, which demonstrates their potential in pharmacological and natural products research. For example, Asian and American tribes use the skin and the parotoid gland secretions of some common toads in the treatment of hemorrhages, bites and stings from venomous animals, skin and stomach disorders, as well as several types of cancers. OVERARCHING OBJECTIVE: In addition to reviewing the occurrence of chemical constituents present in the family Bufonidae, the cytotoxic and biomedical potential of the active compounds produced by different taxa are presented...
December 26, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28029372/cajal-s-unbearable-cephalalgias-the-consequences-of-a-misdiagnosis
#17
REVIEW
S Giménez-Roldán
Around the age of 66 Cajal consulted neurologist Nicolas Achúcarro complaining of "unbearable cephalalgias". He had not ever suffered from headaches. The diagnosis of early arteriosclerosis that was considered at the time a physiological, irreversible ailment of ageing had a strong emotional impact on Cajal. Comorbid depression, insomnia and self-treatment with escalating doses of Veronal(®) (barbital), a short-acting barbiturate, presumably aggravated the situation. Exposure to warm environments and being involved in tense discussions were identified as triggering factors of the headaches...
October 28, 2016: Revue Neurologique
https://www.readbyqxmd.com/read/28029082/probiotics-in-curing-allergic-and-inflammatory-conditions-research-progress-and-futuristic-vision
#18
Kuldeep Dhama, Shyma K Latheef, Ashok Kumar Munjal, Rekha Khandia, Hari Abdul Samad, Hafiz M N Iqbal, Sunil K Joshi
BACKGROUND: Probiotics constitute the viable and beneficial microbes, which offer a dietary means to sustain the balance of gastro-intestinal (GI) microflora. Owing to their multiple health benefits, these have recently gained wide attention among researchers for exploring their potential in safeguarding the health of humans and animals. Probiotics could also modulate host-immune responses, thereby help in counteracting the immunological dysfunctions. Probiotics can inhibit the systemic invasion of pathogens entering through the GI mucosa/ oral cavity and have been found to possess effective prophylactic and therapeutic utilities against various infectious pathogens as well as non-infectious diseases and disorders...
December 26, 2016: Recent Patents on Inflammation & Allergy Drug Discovery
https://www.readbyqxmd.com/read/28028887/phytochemical-analysis-of-a-cytotoxic-fraction-of-quassia-silvestris-using-lc-hr-esi-ms-n
#19
Michel Feussi Tala, Ferdinand Mouafo Talontsi, Guang-Zhi Zeng, Hippolyte Kamdem Wabo, Michael Spiteller, Ning-Hua Tan, Pierre Tane
INTRODUCTION: The genus Quassia is a promising source of secondary metabolites with biological potential including antimalarial and cytotoxic activities. Limited data are available on the phytochemistry and pharmacology of Quassia silvestris Cheek & Jongkind, a Cameroonian medicinal plant used to treat various ailments. OBJECTIVES: To carry out the bioassay-guided fractionation and LC-HR-ESI-MS analyses of the leaves extract from Q. silvestris; to purify the active fractions and isolate the major compounds using different chromatographic and spectroscopic methods...
December 28, 2016: Phytochemical Analysis: PCA
https://www.readbyqxmd.com/read/28027586/targeting-the-mitochondrial-pyruvate-carrier-attenuates-fibrosis-in-a-mouse-model-of-nonalcoholic-steatohepatitis
#20
Kyle S McCommis, Wesley T Hodges, Elizabeth M Brunt, ILKe Nalbantoglu, William G McDonald, Christopher Holley, Hideji Fujiwara, Jean E Schaffer, Jerry R Colca, Brian N Finck
: Diseases of the liver related to metabolic syndrome have emerged as the most common and undertreated hepatic ailments. The cause of nonalcoholic fatty liver disease (NAFLD) is the aberrant accumulation of lipid in hepatocytes, though the mechanisms whereby this leads to hepatocyte dysfunction, death, and hepatic fibrosis are still unclear. Insulin-sensitizing thiazolidinediones have shown efficacy in treating nonalcoholic steatohepatitis (NASH), but their widespread use is constrained by dose-limiting side effects thought to be due to activation of the peroxisome proliferator-activated receptor γ (PPARγ)...
December 27, 2016: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
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