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https://www.readbyqxmd.com/read/28109841/disruption-of-aromatase-homeostasis-as-the-cause-of-a-multiplicity-of-ailments-a-comprehensive-review
#1
REVIEW
Seema Patel
Human health is beset with a legion of ailments, which is exacerbated by the lifestyle errors. Out of the numerous enzymes in human body, aromatase, a cytochromes P450 enzyme is particularly very critical. Occurring at the crossroads of multiple signalling pathways, its homeostasis is vital. Unfortunately, medications, hormone therapy, chemical additives in food, and endocrine-disrupting personal care products are oscillating the aromatase concentration beyond the permissible level. As this enzyme converts androgens (C19) into estrogens (C18), its agitation has different outcomes in different genders and age groups...
January 18, 2017: Journal of Steroid Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/28107157/who-is-in-your-waiting-room-health-care-professionals-as-culturally-responsive-and-trauma-informed-first-responders-to-human-trafficking
#2
Rochelle Rollins, Anna Gribble, Sharon E Barrett, Clydette Powell
Evidence-based practice standards are not yet well defined for assisting potential victims of human trafficking. Nonetheless, health care professionals are learning to be first responders in identifying, treating, and referring potential victims. As more public and private sector resources are used to train health care professionals about human trafficking, more evaluation and research are needed to develop an effective standard of care. Adopting a public health lens and using the "National Standards for Culturally and Linguistically Appropriate Services in Health and Health Care" can guide critical decision making and actions...
January 1, 2017: AMA Journal of Ethics
https://www.readbyqxmd.com/read/28103632/global-health-and-emergency-care-defining-clinical-research-priorities
#3
Bhakti Hansoti, Adam R Aluisio, Meagan A Barry, Kevin Davey, Brian A Lentz, Payal Modi, Jennifer A Newberry, Melissa H Patel, Tricia A Smith, Alexandra M Vinograd, Adam C Levine
OBJECTIVES: Despite recent strides in the development of Global Emergency Medicine (EM), the field continues to lag in applying a scientific approach to identifying critical knowledge gaps and advancing evidence-based solutions to clinical and public health problems seen in emergency departments worldwide. Here, progress on the Global EM research agenda created at the 2013 Academic Emergency Medicine Global Health and Emergency Care Consensus Conference is evaluated and critical areas for future development in emergency care research internationally are identified...
January 19, 2017: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/28093045/exploring-urban-health-in-cape-town-south-africa-an-interdisciplinary-analysis-of-secondary-data
#4
Rebekka Mumm, Sonia Diaz-Monsalve, Eva Hänselmann, Johanna Freund, Michael Wirsching, Jan Gärtner, Richard Gminski, Katrin Vögtlin, Mirjam Körner, Lena Zirn, Ursula Wittwer-Backofen, Tolu Oni, Axel Kroeger
BACKGROUND: With modern information technology, an overwhelming amount of data is available on different aspects of societies. Our research investigated the feasibility of using secondary data sources to get an overview of determinants of health and health outcomes in different population strata of Cape Town, a large city of South Africa. METHODS: The methodological approach of secondary-data analysis was similar in the different disciplines: Biological Anthropology, Public Health, Environmental Health, Mental Health, Palliative Care, Medical Psychology and Sociology at the University of Freiburg and Public Health at the University of Cape Town...
January 17, 2017: Pathogens and Global Health
https://www.readbyqxmd.com/read/28092064/critical-congenital-heart-disease-newborn-screening-implementation-lessons-learned
#5
Monica R McClain, John S Hokanson, Regina Grazel, Kim Naarden Van Braun, Lorraine F Garg, Michelle R Morris, Kathleen Moline, Keri Urquhart, Amy Nance, Harper Randall, Marci K Sontag
Introduction The purpose of this article is to present the collective experiences of six federally-funded critical congenital heart disease (CCHD) newborn screening implementation projects to assist federal and state policy makers and public health to implement CCHD screening. Methods A qualitative assessment and summary from six demonstration project grantees and other state representatives involved in the implementation of CCHD screening programs are presented in the following areas: legislation, provider and family education, screening algorithms and interpretation, data collection and quality improvement, telemedicine, home and rural births, and neonatal intensive care unit populations...
January 16, 2017: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/28090336/medical-feminism-working-mothers-and-the-limits-of-home-finding-a-balance-between-self-care-and-other-care-in-cross-cultural-debates-about-health-and-lifestyle-1952-1956
#6
Frederick Cooper
Post-war medical debates about the psychiatric consequences of married women's economic behaviour witnessed far more divergence and collision between perspectives than has often been acknowledged. Practitioners who approached women primarily as facilitators of family health-as wives and mothers-were mistrustful of the competing demands presented by paid employment. They were faced by a growing spectrum of opinion, however, which represented women as atrophying in the confines of domestic life, and which positioned work as a therapeutic act...
July 12, 2016: Palgrave Communications
https://www.readbyqxmd.com/read/28061835/a-comparative-assessment-of-major-international-disasters-the-need-for-exposure-assessment-systematic-emergency-preparedness-and-lifetime-health-care
#7
Roberto G Lucchini, Dana Hashim, Sushma Acquilla, Angela Basanets, Pier Alberto Bertazzi, Andrey Bushmanov, Michael Crane, Denise J Harrison, William Holden, Philip J Landrigan, Benjamin J Luft, Paolo Mocarelli, Nailya Mazitova, James Melius, Jacqueline M Moline, Koji Mori, David Prezant, Joan Reibman, Dori B Reissman, Alexander Stazharau, Ken Takahashi, Iris G Udasin, Andrew C Todd
BACKGROUND: The disasters at Seveso, Three Mile Island, Bhopal, Chernobyl, the World Trade Center (WTC) and Fukushima had historic health and economic sequelae for large populations of workers, responders and community members. METHODS: Comparative data from these events were collected to derive indications for future preparedness. Information from the primary sources and a literature review addressed: i) exposure assessment; ii) exposed populations; iii) health surveillance; iv) follow-up and research outputs; v) observed physical and mental health effects; vi) treatment and benefits; and vii) outreach activities...
January 7, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28051972/characteristics-classification-and-prevention-of-child-maltreatment-fatalities
#8
James E McCarroll, Joscelyn E Fisher, Stephen J Cozza, Renè J Robichaux, Carol S Fullerton
BACKGROUND: Preventing child maltreatment fatalities is a critical goal of the U.S. society and the military services. Fatality review boards further this goal through the analysis of circumstances of child deaths, making recommendations for improvements in practices and policies, and promoting increased cooperation among the many systems that serve families. The purpose of this article is to review types of child maltreatment death, proposed classification models, risk and protective factors, and prevention strategies...
January 2017: Military Medicine
https://www.readbyqxmd.com/read/28039845/midwives-perceptions-and-experiences-of-caring-for-women-who-experience-perinatal-mental-health-problems-an-integrative-review
#9
REVIEW
Maria Noonan, Owen Doody, Julie Jomeen, Rose Galvin
BACKGROUND: perinatal mental health is an important public health issue and consideration must be given to care provision for effective support and care of women in the perinatal period. AIM: to synthesise primary research on midwives' perceived role in Perinatal Mental Health (PMH). DESIGN: integrative review. METHODS: Whittemore and Knafl's (2005) framework was employed. A systematic search of the literature was completed...
December 12, 2016: Midwifery
https://www.readbyqxmd.com/read/28032779/the-era-of-sport-concussion-evolution-of-knowledge-practice-and-the-role-of-psychology
#10
Julie L Guay, Brittany M Lebretore, Jesse M Main, Katelyn E DeFrangesco, Jessica L Taylor, Sarah M Amedoro
The topic of sport concussion has gained significant prominence over the last 20 years, resulting in dramatic growth in research funding, widespread media coverage, and increased public awareness. Although the knowledge base has greatly expanded, there is still much that is unknown or controversial about the long-term effects of sports-related head injury. Because of the high stakes of mismanaging these injuries, professional sports organizations, federal/state government, and various health-related disciplines have responded with efforts to educate the public and improve treatment and management of this injury...
December 2016: American Psychologist
https://www.readbyqxmd.com/read/28031046/what-is-the-effectiveness-of-obesity-related-interventions-at-retail-grocery-stores-and-supermarkets-a-systematic-review
#11
Abdulfatah Adam, Jørgen D Jensen
BACKGROUND: The Prevalence of obesity and overweight has been increasing in many countries. Many factors have been identified as contributing to obesity including the food environment, especially the access, availability and affordability of healthy foods in grocery stores and supermarkets. Several interventions have been carried out in retail grocery/supermarket settings as part of an effort to understand and influence consumption of healthful foods. The review's key outcome variable is sale/purchase of healthy foods as a result of the interventions...
December 28, 2016: BMC Public Health
https://www.readbyqxmd.com/read/28025323/role-of-emerging-private-hospitals-in-a-post-soviet-mixed-health-system-a-mixed-methods-comparative-study-of-private-and-public-hospital-inpatient-care-in-mongolia
#12
Uranchimeg Tsevelvaanchig, Hebe Gouda, Peter Baker, Peter S Hill
BACKGROUND: The collapse of the Soviet Union in 1990 severely impacted the health sector in Mongolia. Limited public funding for the post-Soviet model public system and a rapid growth of poorly regulated private providers have been pressing issues for a government seeking to re-establish universal health coverage. However, the evidence available on the role of private providers that would inform sector management is very limited. This study analyses the current contribution of private hospitals in Mongolia for the improvement of accessibility of health care and efficiency...
December 26, 2016: Health Policy and Planning
https://www.readbyqxmd.com/read/28025018/pharmacy-provision-of-sexual-and-reproductive-health-commodities-to-young-people-a-systematic-literature-review-and-synthesis-of-the-evidence
#13
REVIEW
Lianne Gonsalves, Michelle J Hindin
BACKGROUND: We conducted a systematic review of peer-reviewed literature on youth access to, use of and quality of care of sexual and reproductive health (SRH) commodities through pharmacies. METHODS: Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) protocol, we searched for publications from 2000 to 2016. To be eligible for inclusion, articles had to address the experiences of young people (aged 25 years and below) accessing SRH commodities (e...
December 23, 2016: Contraception
https://www.readbyqxmd.com/read/28013098/toward-precision-smoking-cessation-treatment-i-moderator-results-from-a-factorial-experiment
#14
Megan E Piper, Tanya R Schlam, Jessica W Cook, Stevens S Smith, Daniel M Bolt, Wei-Yin Loh, Robin Mermelstein, Linda M Collins, Michael C Fiore, Timothy B Baker
BACKGROUND: The development of tobacco use treatments that are effective for all smokers is critical to improving clinical and public health. The Multiphase Optimization Strategy (MOST) uses highly efficient factorial experiments to evaluate multiple intervention components for possible inclusion in an optimized tobacco use treatment. Factorial experiments permit analyses of the influence of patient characteristics on main and interaction effects of multiple, relatively discrete, intervention components...
November 25, 2016: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/27992726/public-health-surveillance-systems-recent-advances-in-their-use-and-evaluation
#15
Samuel L Groseclose, David L Buckeridge
Surveillance is critical for improving population health. Public health surveillance systems generate information that drives action, and the data must be of sufficient quality and with a resolution and timeliness that matches objectives. In the context of scientific advances in public health surveillance, changing health care and public health environments, and rapidly evolving technologies, the aim of this article is to review public health surveillance systems. We consider their current use to increase the efficiency and effectiveness of the public health system, the role of system stakeholders, the analysis and interpretation of surveillance data, approaches to system monitoring and evaluation, and opportunities for future advances in terms of increased scientific rigor, outcomes-focused research, and health informatics...
December 15, 2016: Annual Review of Public Health
https://www.readbyqxmd.com/read/27982284/-rhd-alloimmunization-in-pregnant-women-in-rio-de-janeiro-state-brazil-perspectives-and-challenges
#16
Ana Heloisa Nascimento Beserra, Elizabeth Artmann, Maria Cristina Pessoa Dos Santos
This study shows research results on the persistence of RhD alloimmunization in pregnant women seen in the public healthcare network in Rio de Janeiro State, Brazil, through patient file analysis and interviews with administrators, health professionals, and patients. We analyzed 289 patient files of RhD-negative pregnant women seen from 2004 to 2012 at the State Reference Center. Individual interviews were held with 15 individuals. The interviews revealed factors contributing to persistence of the problem, such as: loss of restructuring of the Program for the Prevention of RhD Alloimmunization (PPARhD); lack of a system for monitoring the Program; low linkage between the referral and counter-referral network during prenatal care; insufficient training of the health professionals treating pregnant women at risk; and insufficient visibility of the program for RhD alloimmunization prevention...
November 1, 2016: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/27977393/impact-of-hypertension-on-cognitive-function-a-scientific-statement-from-the-american-heart-association
#17
Costantino Iadecola, Kristine Yaffe, José Biller, Lisa C Bratzke, Frank M Faraci, Philip B Gorelick, Martha Gulati, Hooman Kamel, David S Knopman, Lenore J Launer, Jane S Saczynski, Sudha Seshadri, Adina Zeki Al Hazzouri
BACKGROUND: Age-related dementia, most commonly caused by Alzheimer disease or cerebrovascular factors (vascular dementia), is a major public health threat. Chronic arterial hypertension is a well-established risk factor for both types of dementia, but the link between hypertension and its treatment and cognition remains poorly understood. In this scientific statement, a multidisciplinary team of experts examines the impact of hypertension on cognition to assess the state of the knowledge, to identify gaps, and to provide future directions...
December 2016: Hypertension
https://www.readbyqxmd.com/read/27911897/heterologous-protection-against-asian-zika-virus-challenge-in-rhesus-macaques
#18
Matthew T Aliota, Dawn M Dudley, Christina M Newman, Emma L Mohr, Dane D Gellerup, Meghan E Breitbach, Connor R Buechler, Mustafa N Rasheed, Mariel S Mohns, Andrea M Weiler, Gabrielle L Barry, Kim L Weisgrau, Josh A Eudailey, Eva G Rakasz, Logan J Vosler, Jennifer Post, Saverio Capuano, Thaddeus G Golos, Sallie R Permar, Jorge E Osorio, Thomas C Friedrich, Shelby L O'Connor, David H O'Connor
BACKGROUND: Zika virus (ZIKV; Flaviviridae, Flavivirus) was declared a public health emergency of international concern by the World Health Organization (WHO) in February 2016, because of the evidence linking infection with ZIKV to neurological complications, such as Guillain-Barre Syndrome in adults and congenital birth defects including microcephaly in the developing fetus. Because development of a ZIKV vaccine is a top research priority and because the genetic and antigenic variability of many RNA viruses limits the effectiveness of vaccines, assessing whether immunity elicited against one ZIKV strain is sufficient to confer broad protection against all ZIKV strains is critical...
December 2016: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/27911073/reducing-risky-alcohol-use-what-health-care-systems-can-do
#19
Amity E Quinn, Mary Brolin, Maureen T Stewart, Brooke Evans, Constance Horgan
Risky, non-dependent alcohol use is prevalent in the United States, affecting 25% of adults (Centers for Disease Control and Prevention, 2014b). Massachusetts has higher rates of alcohol use and binge drinking than most states (Substance Abuse and Mental Health Services Administration, 2015). Serious physical, social, and economic consequences result. Excessive alcohol use contributes to cancer, cardiovascular disease, sleep disorders, birth defects, motor vehicle injuries, and suicide, and it complicates management of chronic illnesses (Green, McKnight-Eily, Tan, Mejia, & Denny, 2016; Laramee et al...
April 27, 2016: Issue Brief
https://www.readbyqxmd.com/read/27876082/evaluating-data-abstraction-assistant-a-novel-software-application-for-data-abstraction-during-systematic-reviews-protocol-for-a-randomized-controlled-trial
#20
Ian J Saldanha, Christopher H Schmid, Joseph Lau, Kay Dickersin, Jesse A Berlin, Jens Jap, Bryant T Smith, Simona Carini, Wiley Chan, Berry De Bruijn, Byron C Wallace, Susan M Hutfless, Ida Sim, M Hassan Murad, Sandra A Walsh, Elizabeth J Whamond, Tianjing Li
BACKGROUND: Data abstraction, a critical systematic review step, is time-consuming and prone to errors. Current standards for approaches to data abstraction rest on a weak evidence base. We developed the Data Abstraction Assistant (DAA), a novel software application designed to facilitate the abstraction process by allowing users to (1) view study article PDFs juxtaposed to electronic data abstraction forms linked to a data abstraction system, (2) highlight (or "pin") the location of the text in the PDF, and (3) copy relevant text from the PDF into the form...
November 22, 2016: Systematic Reviews
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