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https://www.readbyqxmd.com/read/29443414/neonatal-outcomes-after-fetal-exposure-to-methadone-and-buprenorphine-national-registry-studies-from-the-czech-republic-and-norway
#1
Blanka Nechanská, Viktor Mravčík, Svetlana Skurtveit, Ingunn Olea Lund, Roman Gabrhelík, Anders Engeland, Marte Handal
BACKGROUND AND AIMS: Opioid maintenance treatment (OMT) is recommended to opioid dependent females during pregnancy. However, it is not clear which medication should be preferred. We aimed to compare neonatal outcomes after prenatal exposure to methadone (M) and buprenorphine (B) in two European countries. DESIGN: Nationwide register-based cohort study using personalized IDs assigned to all citizens for data linkage. SETTING: The Czech Republic (2000-2014) and Norway (2004-2013)...
February 14, 2018: Addiction
https://www.readbyqxmd.com/read/29434993/prediction-of-decannulation-oral-intake-recovery-overall-survival-and-lung-metastasis-following-oral-malignant-tumor-resection-and-reconstruction
#2
Hidenori Suzuki, Ikuo Hyodo, Yasuhisa Hasegawa
The present study investigated whether tongue base and mandibular bone defects were associated with the rate of decannulation and oral intake recovery, and survival time, including overall and lung metastasis-free survival time, in patients that underwent oral malignant tumor (OMT) resection with reconstruction. A total of 105 patients that underwent OMT resection with laryngeal preservation and reconstruction were recruited. The extent of defects was classified according to Urken's classification. The rates of decannulation and oral intake recovery were assessed with the Kaplan-Meier method...
February 2018: Oncology Letters
https://www.readbyqxmd.com/read/29424731/efficacy-of-cardiac-shock-wave-therapy-in-patients-with-stable-angina-the-design-of-randomized-triple-blind-sham-procedure-controlled-study
#3
Evgeny Shkolnik, Greta Burneikaite, Jelena Celutkiene, Mikhail Scherbak, Gitana Zuoziene, Birute Petrauskiene, Ekaterina Trush, Aleksandras Laucevicius, Yury Vasyuk
OBJECTIVE: Despite revascularization and optimal medical treatment (OMT), patients with angina often have a reduced quality of life due to inadequate relief from symptoms. Recent studies have shown that the application of shock waves may reduce angina symptoms and improve quality of life, exercise capacity, and myocardial perfusion due to the stimulation of angiogenesis. However, there is limited evidence due to small, single-arm, single-center studies of low to moderate quality. The purpose of this study is to evaluate the impact of cardiac shock wave therapy (CSWT) on exercise tolerance and angina symptoms in patients with coronary artery disease and objective evidence of myocardial ischemia who cannot undergo traditional revascularization and experience angina despite OMT in comparison to sham procedure...
February 2018: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/29412368/effects-of-orofacial-myofunctional-therapy-on-masticatory-function-in-individuals-submitted-to-orthognathic-surgery-a-randomized-trial
#4
Daniela Galvão de Almeida Prado, Giédre Berretin-Felix, Renata Resina Migliorucci, Mariana da Rocha Salles Bueno, Raquel Rodrigues Rosa, Marcela Polizel, Isadora Ferraz Teixeira, Maria Beatriz Duarte Gavião
OBJECTIVES: The esthetic and functional results of orthognathic surgery of severe dentofacial deformities are predictable, however there are differences regarding the effects on stomatognathic system. The aim was to investigate the effects of orofacial myofunctional therapy (OMT) on the masticatory function in individuals with dentofacial deformity submitted to orthognathic surgery (OGS). MATERIAL AND METHODS: Forty-eight individuals (18-40 years) were evaluated, 14 undergoing OMT (treated group-TG), 10 without this treatment (untreated group-UTG) and 24 in a control group with normal occlusion; for clinical aspects the data of an individual was missed (n=46)...
February 1, 2018: Journal of Applied Oral Science: Revista FOB
https://www.readbyqxmd.com/read/29402837/protective-effects-of-oxymatrine-on-vascular-endothelial-cells-from-high-glucose-induced-cytotoxicity-by-inhibiting-the-expression-of-a2b-receptor
#5
Yun Yi, Yulin Shen, Qin Wu, Jingan Rao, Shu Guan, Shenqiang Rao, Liping Huang, Mengxia Tan, Lingkun He, Lijuan Liu, Guodong Li, Shangdong Liang, Wei Xiong, Yun Gao
BACKGROUND/AIMS: Diabetes mellitus (DM) has become an increasingly epidemic metabolic disease. Vascular endothelial cells play a key role in developing the cardiovascular complications of DM. The A2B receptor is expressed in vascular endothelial cells, and may help regulate the function of endothelial cells. The aim of this study was to investigate the protective effects of oxymatrine (OMT) on human umbilical vein endothelial cells (HUVECs) from high glucose-induced cytotoxicity. METHODS: Homology modeling and molecular docking analysis were used to detect the binding sites between the adenosine A2B receptor and OMT...
January 25, 2018: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/29394340/trends-in-optimal-medical-therapy-prescription-and-mortality-after-admission-for-acute-coronary-syndrome-a-9-year-experience-in-a-real-world-setting
#6
N P G Hoedemaker, P Damman, J P Ottervanger, J H E Dambrink, A T M Gosselink, E Kedhi, E Kolkman, R J de Winter, A W J van 't Hof
Aims: Optimal medical therapy (OMT) is recommended in acute coronary syndrome (ACS) patients. Few studies present temporal trends of OMT prescription and its impact on outcomes in a real-world setting. We aimed to evaluate OMT prescription in a real-world ACS population and its relation to mortality during almost a decade. Methods and results: Consecutive STEMI and NSTEMI patients (n = 9202) admitted to a single Dutch tertiary hospital between 2006-2014 were included and followed for drug prescription and mortality up to 1 year...
January 30, 2018: European Heart Journal. Cardiovascular Pharmacotherapy
https://www.readbyqxmd.com/read/29388822/improving-the-assessment-of-implicit-motives-using-irt-cultural-differences-and-differential-item-functioning
#7
J Malte Runge, Jonas W B Lang, Athanasios Chasiotis, Jan Hofer
Researchers have long been interested in studying differences in implicit motive between different groups. Implicit motives are typically measured by scoring text that respondents have written in response to picture cues. Recently, research on the measurement of implicit motives has made progress through the application of a dynamic Thurstonian item-response theory model (DTM; Lang, 2014 ) that captures 2 basic motivational processes in motivational research: motive competition and dynamic reduction of motive strength after a motive has been acted out...
February 1, 2018: Journal of Personality Assessment
https://www.readbyqxmd.com/read/29385340/thermal-population-fluctuations-in-two-dimensional-infrared-spectroscopy-captured-with-semiclassical-mechanics
#8
Prashanth Ramesh, Roger F Loring
Time-resolved two-dimensional (2D) infrared spectra of the asymmetric stretch mode of solvated CO2 show distinct features corresponding to ground and excited state thermal populations of the bend modes. The time-dependence of these peaks arises in part from solvent-driven thermal fluctuations in populations of the lower frequency bend modes through their coupling to the higher frequency asymmetric stretch. This observation illustrates the capacity of multidimensional vibrational spectroscopy to reveal details of the interactions among vibrational modes in condensed phases...
January 31, 2018: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/29379976/omt-to-address-the-physiologic-effects-of-stress
#9
Danielle Emmet, Victor Nuño, Stacey Pierce-Talsma
No abstract text is available yet for this article.
February 1, 2018: Journal of the American Osteopathic Association
https://www.readbyqxmd.com/read/29323788/constructing-ordered-three-dimensional-channels-of-tio2-for-enhanced-visible-light-photo-catalytic-performance-of-co2-conversion-induced-by-au-nanoparticles
#10
Hairong Xue, Tao Wang, Hao Gong, Hu Guo, Xiaoli Fan, Bin Gao, Yaya Feng, Xianguang Meng, Xianli Huang, Jianping He
As a typical photo-catalyst for CO2 reduction, the practical application of TiO2 still suffers from low photo-catalytic efficiency and limited visible light absorption. Here, a novel Au-nanoparticle (NP)-decorated ordered mesoporous TiO2 (OMT) composite (OMT-Au) was successfully fabricated, in which Au NPs uniformly disperse on the OMT. Due to the surface plasmon resonance (SPR) effect derived from the excited Au NPs, TiO2 possesses high photo-catalytic performance for CO2 reduction under visible light. The ordered mesoporous exhibits the superiority of material and structure...
January 11, 2018: Chemistry, An Asian Journal
https://www.readbyqxmd.com/read/29320768/attention-deficit-hyperactivity-disorder-symptoms-are-common-in-patients-in-opioid-maintenance-treatment
#11
Kristine Fiksdal Abel, Edle Ravndal, Thomas Clausen, Jørgen G Bramness
INTRODUCTION AND AIMS: Knowledge of attention deficit hyperactivity disorder (ADHD) symptoms among patients in opioid maintenance treatment (OMT) is important for treatment optimization and yet limited. We investigated the prevalence of ADHD symptoms, and factors associated with high ADHD symptom burden in a group of Norwegian OMT patients. METHODS: We interviewed individuals entering OMT across Norway in 2 steps between 2012 and 2016. ADHD symptoms were measured by the Adult ADHD Self-Report Scale (ASRS; n = 175)...
2017: European Addiction Research
https://www.readbyqxmd.com/read/29309103/omt-for-cancer-patients-after-bowel-resection
#12
Nicole Peña, Helena Prieto, Stacey Pierce-Talsma
No abstract text is available yet for this article.
January 1, 2018: Journal of the American Osteopathic Association
https://www.readbyqxmd.com/read/29309095/omt-may-be-helpful-in-the-management-of-benign-paroxysmal-positional-vertigo
#13
Luke Tegeler, Janice Blumer
No abstract text is available yet for this article.
January 1, 2018: Journal of the American Osteopathic Association
https://www.readbyqxmd.com/read/29303399/perceived-self-control-is-related-to-mental-distress-in-patients-entering-substance-use-disorder-treatment
#14
Kristine Fiksdal Abel, Ingeborg Skjærvø, Edle Ravndal, Thomas Clausen, Jørgen G Bramness
BACKGROUND: Levels of mental distress are high in patients with substance use disorders (SUD) and investigation of correlates may broaden our understanding of this comorbidity. OBJECTIVES: We investigated self-reported symptoms of mental distress among individuals entering either outpatient opioid maintenance treatment (OMT) or other inpatient SUD treatment and related factors, with a particular focus on perceived self-control. METHODS: A cross-sectional study including substance users (n = 548; mean age 34 years; 27% women) entering treatment at 21 different treatment-centers across Norway, interviewed between December 2012 and April 2015...
January 5, 2018: Substance Use & Misuse
https://www.readbyqxmd.com/read/29218605/oxymatrine-sensitizes-the-hacat-cells-to-the-ifn-%C3%AE-pathway-and-downregulates-mdc-icam-1-and-socs1-by-activating-p38-jnk-and-akt
#15
Chun-Jie Gao, Pei-Jun Ding, Li-Li Yang, Xu-Feng He, Meng-Jiao Chen, Dong-Ming Wang, Yan-Xin Tian, Hui-Min Zhang
Decreased interferon (IFN)-γ levels and increased levels of macrophage-derived chemokine (MDC) and intercellular adhesion molecule (ICAM)-1 are known to be involved in allergic skin diseases, such as eczema and atopic dermatitis. Activation of the IFN-γ and its downstream interleukin-12 (IL-12) pathway can correct these diseases. Suppressor of cytokine signaling 1 (SOCS1) is a cytokine signaling inhibitor that blocks downstream pathways of IFN-γ by blocking the mitogen-activated protein kinase (MAPK) and protein kinase B (Akt) signaling pathways...
December 7, 2017: Inflammation
https://www.readbyqxmd.com/read/29202144/best-uses-of-osteopathic-manipulation
#16
REVIEW
Andrew H Slattengren, Tanner Nissly, Jodi Blustin, Andrew Bader, Erin Westfall
With the growing number of DOs and the high utilization of osteopathic manipulative treatment (OMT), it is important for all physicians to understand the role OMT can play in the treatment of conditions ranging from low back pain to irritable bowel syndrome so that patients may be offered, or referred for, the treatment when appropriate.
December 2017: Journal of Family Practice
https://www.readbyqxmd.com/read/29200050/a-call-for-compassionate-care
#17
Karen Alexander
The Substance Abuse and Mental Health Services Administration (2014) reported that 1.1% of pregnant women used nonprescription opiates (either heroin or prescription pills) in the last 30 days. Methadone and buprenorphine are the most common treatments for opiate addiction in pregnant women. Reasons for seeking opiate maintenance treatment (OMT) include keeping custody of one's children and the hope of developing a healthy parenting relationship. Yet, healthcare organizations and professionals have mixed opinions regarding health promotion within the maternal OMT population...
October 2017: Journal of Addictions Nursing
https://www.readbyqxmd.com/read/29181525/omt-for-patients-with-multiple-sclerosis
#18
Kimberly Wolf, Tracy Krinard, Joel Talsma, Stacey Pierce-Talsma
No abstract text is available yet for this article.
December 1, 2017: Journal of the American Osteopathic Association
https://www.readbyqxmd.com/read/29161956/percutaneous-repair-of-mitral-valve-regurgitation-in-patients-with-severe-heart-failure-comparison-with-optimal-medical-treatment
#19
Nicolas Geis, Philip Raake, Markus Lewening, Derliz Mereles, Emmanuel Chorianopoulos, Lutz Frankenstein, Hugo A Katus, Raffi Bekeredjian, Sven T Pleger
BACKGROUND: Occurrence of severe mitral valve (MV) regurgitation (MR) is an independent negative predictor of mortality in patients with severe systolic heart failure (HF). This study examines clinical effects and cardiac reverse remodelling in patients with severe systolic HF receiving percutaneous mitral valve repair (PMVR) using MitraClip in comparison to patients receiving optimal medical therapy only. METHODS: Between 2010 and 2014, 86 patients (Society of Thoracic Surgeons score: 10...
November 21, 2017: Acta Cardiologica
https://www.readbyqxmd.com/read/29151028/variations-in-use-of-optimal-medical-therapy-in-patients-with-nonobstructive-coronary-artery-disease-a-population-based-study
#20
Adam Oxner, Gabby Elbaz-Greener, Feng Qui, Shannon Masih, Nevena Zivkovic, Sami Alnasser, Asim N Cheema, Harindra C Wijeysundera
BACKGROUND: There is a paucity of data on the need for optimal medical therapy (OMT) in nonobstructive coronary artery disease . We sought to understand if there was variation in the use of OMT between hospitals for patients with nonobstructive coronary artery disease, the factors associated with such variation, and its clinical consequences. METHODS AND RESULTS: Using a population-level clinical registry in Ontario, Canada, we identified all patients >66 years undergoing coronary angiography for the indication of stable angina, who had nonobstructive coronary artery disease between November 1, 2010, and October 31, 2013...
November 18, 2017: Journal of the American Heart Association
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