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https://www.readbyqxmd.com/read/29159007/acute-brachial-artery-occlusion-in-an-elderly-patient-with-acute-myocardial-ischemia
#1
Gabriel O Ologun, Christian Bohan, Tiffany Lau, Mohammad Sultany, Andrew Trecartin, Zachary Wolfe, Silviu Marica, Lawrence Sampson, Umashankar Ballehaninna
We present a case of left upper extremity paresis secondary to acute brachial artery occlusion in an elderly female with active non-ST segment elevation myocardial ischemia (NSTEMI) in the setting of paroxysmal atrial fibrillation. The patient was initially suspected to have a cerebrovascular attack (CVA); however, computed tomography (CT) head was negative for acute stroke. The diagnosis was confirmed by computed tomographic angiography (CTA) of the upper extremity, confirming the diagnosis of acute left brachial artery occlusion...
September 19, 2017: Curēus
https://www.readbyqxmd.com/read/29153561/use-of-atrial-strain-to-predict-atrial-fibrillation-after-cerebral-ischemia
#2
Faraz Pathan, Eswar Sivaraj, Kazuaki Negishi, Rifly Rafiudeen, Shahab Pathan, Nicholas D'Elia, John Galligan, Samuel Neilson, Ricardo Fonseca, Thomas H Marwick
OBJECTIVES: This study sought to identify whether atrial strain could be used as an imaging biomarker to predict atrial fibrillation (AF). BACKGROUND: AF is found in up to 30% of cryptogenic cerebrovascular accidents (CVAs), which themselves account for 30% to 40% of ischemic CVA. METHODS: This observational study evaluated all patients who had an echocardiogram (transthoracic echocardiogram [TTE]) following presentation with cryptogenic CVA from 2010 to 2014...
November 10, 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29143297/impact-of-trimetazidine-treatment-on-5-year-clinical-outcomes-in-patients-with-significant-coronary-artery-spasm-a-propensity-score-matching-study
#3
Yong Hoon Kim, Ae-Young Her, Seung-Woon Rha, Byoung Geol Choi, Se Yeon Choi, Jae Kyeong Byun, Ahmed Mashaly, Yoonjee Park, Won Young Jang, Woohyeun Kim, Jah Yeon Choi, Eun Jin Park, Jin Oh Na, Cheol Ung Choi, Hong Euy Lim, Eung Ju Kim, Chang Gyu Park, Hong Seog Seo, Dong Joo Oh
OBJECTIVE: We aimed to evaluate the additive benefit of trimetazidine with well-known antispasmodic agents such as calcium channel blockers and nitrate in patients with significant coronary artery spasm (CAS) as assessed by acetylcholine provocation test up to 5 years. METHODS: A total 1727 patients with significant CAS were enrolled. They were divided into two groups: a trimetazidine group (trimetazidine, diltiazem, and nitrate, n = 695), and control group (diltiazem and nitrate, n = 473)...
November 15, 2017: American Journal of Cardiovascular Drugs: Drugs, Devices, and Other Interventions
https://www.readbyqxmd.com/read/29132199/non-fasting-triglyceride-levels-in-the-korean-population-with-and-without-ischemic-heart-disease-and-cerebrovascular-disease
#4
Seo Young Lee, Bo Kyung Koo, Min Kyong Moon
Background/Aims: Associations between non-fasting triglyceride (TG) levels and a risk of ischemic heart disease (IHD) and cerebrovascular accident (CVA) have been suggested in Caucasians. We aimed to investigate whether non-fasting TG levels reflect the risk of IHD/CVA in Koreans. Methods: We conducted an analysis of patients aged ≥ 30 years from the nationwide survey database. Fasting TG was defined as a measurement taken ≥ 12 hours since the last meal. Non-fasting TG was categorized by fasting duration of 0 to 3, 4 to 7, and 8 to 11 hours...
November 15, 2017: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/29131434/five-year-impact-of-catheter-ablation-for-atrial-fibrillation-in-patients-with-a-prior-history-of-stroke
#5
T Jared Bunch, Heidi T May, Tami L Bair, Brian G Crandall, Michael J Cutler, John D Day, Victoria Jacobs, Charles Mallender, Jeffrey S Osborn, J Peter Weiss
BACKGROUND: Catheter ablation of atrial fibrillation(AF) is an established therapeutic rhythm approach. Patients with a prior history of a stroke(CVA) represent a unique high-risk population for recurrent thromboembolic events. The role of antiarrhythmic treatment on the natural history of stroke recurrence in these patients is not fully understood. METHODS: Three patient groups with a prior CVA and 5 years of follow-up were matched 1:3:3 by propensity score(±0...
November 13, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/29130497/ubc-nepal-expedition-acclimatization-to-high-altitude-increases-spinal-motoneurone-excitability-during-fatigue-in-humans
#6
Luca Ruggiero, Alexandra F Yacyshyn, Jane Nettleton, Chris J McNeil
The fatigue-induced failure of the motor cortex to drive muscles maximally increases in acute hypoxia (AH) compared to normoxia (N) but improves with acclimatization (chronic hypoxia; CH). Despite their importance to muscle output, it is unknown how locomotor motoneurones in humans are affected by hypoxia and acclimatization. Eleven participants performed 16 min of submaximal (25% maximal torque, MVC) intermittent isometric elbow flexions in N, AH (environmental chamber), and CH (7-14 days at 5050 m) (PI O2 =  140, 74, and 76 mmHg, respectively)...
November 11, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/29111342/the-use-of-repetitive-transcranial-magnetic-stimulation-for-stroke-rehabilitation-a-systematic-review
#7
REVIEW
Ana Dionísio, Isabel Catarina Duarte, Miguel Patrício, Miguel Castelo-Branco
OBJECTIVES: Stroke is a leading cause of disability. Alternative and more effective techniques for stroke rehabilitation have been sought to overcome limitations of conventional therapies. Repetitive transcranial magnetic stimulation (rTMS) arises as a promising tool in this context. This systematic review aims to provide a state of the art on the application of rTMS in stroke patients and to assess its effectiveness in clinical rehabilitation of motor function. METHODS: Studies included in this review were identified by searching PubMed and ISI Web of Science...
October 27, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29107011/moving-standard-deviation-and-moving-sum-of-outliers-as-quality-tools-for-monitoring-analytical-precision
#8
Jiakai Liu, Chin Hon Tan, Tony Badrick, Tze Ping Loh
INTRODUCTION: An increase in analytical imprecision (expressed as CVa) can introduce additional variability (i.e. noise) to the patient results, which poses a challenge to the optimal management of patients. Relatively little work has been done to address the need for continuous monitoring of analytical imprecision. METHODS: Through numerical simulations, we describe the use of moving standard deviation (MovSD) and a recently described moving sum of outlier (movSO) patient results as means for detecting increased analytical imprecision, and compare their performances against internal quality control (QC) and the average of normal (AoN) approaches...
October 26, 2017: Clinical Biochemistry
https://www.readbyqxmd.com/read/29098973/-changes-in-cause-of-death-statistics-as-a-consequence-of-automated-coding
#9
P P M Harteloh
In 2013, Statistics Netherlands (CBS) has switched to an automated system for coding causes of death (IRIS). This change of method breaks with the tradition of manual coding of death certificates by medical coders that has lasted for over one hundred years. This article covers the major changes in the frequency of causes of death. It describes an increase of dementia (23%), CVA (11%), infectious diseases (43%) and risk factors (48%) as the underlying cause of death. Researchers, policy makers and medical doctors should take into account the differences between manual and automated coding when interpreting trends or comparing countries...
2017: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/29097159/the-epidemiology-and-clinical-associations-of-stroke-in-patients-with-acute-myeloid-leukemia-a-review-of-10-972-admissions-from-the-2012-national-inpatient-sample
#10
Christopher Del Prete, Taeha Kim, Frederick Lansigan, Joseph Shatzel, Harley Friedman
BACKGROUND: Acute leukemia is known to confer an elevated risk of both hemorrhagic and thrombotic complications, but the development of stroke in this population is poorly characterized. This study assesses clinical and epidemiologic factors in a population of inpatients with acute myeloid leukemia (AML) and stroke. METHODS: Using the 2012 National Inpatient Sample, demographic and clinical data including age, gender, race, length of stay, in-hospital procedures, discharge diagnosis, disposition, and mortality incidence were extracted...
September 20, 2017: Clinical Lymphoma, Myeloma & Leukemia
https://www.readbyqxmd.com/read/29092740/preoperative-aldosterone-receptor-blockade-and-outcomes-of-cardiac-surgery-in-patients-with-chronic-kidney-disease%C3%A2
#11
Linda Shavit, Shuli Silberman, Rachel Tauber, Ofer Merin, Daniel Bitran, Daniel Fink
BACKGROUND AND AIMS: Recent clinical evidence demonstrates that chronic low-dose mineralocorticoid receptor antagonists (MRA), when added to optimal treatment, result in reductions in cardiovascular mortality. However, continuation of MRAs before cardiac surgery in patients with CKD has never been evaluated and its potential benefit or harm in this specific clinical setting is largely unknown. MATERIALS AND METHODS: This is an observational study that included adult CKD patients undergoing cardiac surgery...
October 26, 2017: Clinical Nephrology
https://www.readbyqxmd.com/read/29079358/monoclonal-protein-reference-change-value-as-determined-by-gel-based-serum-protein-electrophoresis
#12
Mina Salamatmanesh, Christopher R McCudden, Arleigh McCurdy, Ronald A Booth
INTRODUCTION: The International Myeloma Working Group recommendations for monitoring disease progression or response include quantitation of the involved monoclonal immunoglobulin. They have defined the minimum change criteria of ≧25% with an absolute change of no <5g/L for either minimal response or progression. Limited evidence is available to accurately determine the magnitude of change in a monoclonal protein to reflect a true change in clinical status. Here we determined the analytical and biological variability of monoclonal proteins in stable monoclonal gammopathy of undetermined significance (MGUS) patients...
October 24, 2017: Clinical Biochemistry
https://www.readbyqxmd.com/read/29057963/impact-of-analytical-and-biological-variations-on-classification-of-diabetes-using-fasting-plasma-glucose-oral-glucose-tolerance-test-and-hba1c
#13
Jia Hui Chai, Stefan Ma, Derick Heng, Joanne Yoong, Wei-Yen Lim, Sue-Anne Toh, Tze Ping Loh
Historically, diabetes is diagnosed by measuring fasting (FPG) and two-hour post oral glucose load (OGTT) plasma concentration and interpreting it against recommended clinical thresholds of the patient. More recently, glycated haemoglobin A1c (HbA1c) has been included as a diagnostic criterion. Within-individual biological variation (CVi), analytical variation (CVa) and analytical bias of a test can impact on the accuracy and reproducibility of the classification of a disease. A test with large biological and analytical variation increases the likelihood of erroneous classification of the underlying disease state of a patient...
October 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29040224/fes-assisted-cycling-improves-aerobic-capacity-and-locomotor-function-post-cva
#14
Stacey E Aaron, Catherine J VanDerwerker, Aaron E Embry, Jennifer H Newton, Samuel C K Lee, Chris M Gregory
PURPOSE: After a cerebrovascular accident (CVA) aerobic deconditioning contributes to diminished physical function. Functional Electrical Stimulation (FES)-assisted cycling is a promising exercise paradigm designed to target both aerobic capacity and locomotor function. This pilot study aimed to evaluate the effects of an FES-assisted cycling intervention on aerobic capacity and locomotor function in individuals post-CVA. METHODS: Eleven individuals with chronic (> 6 months) post-CVA hemiparesis completed an 8-week (3x/wk; 24 sessions) progressive FES-assisted cycling intervention...
October 16, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29020049/further-insight-into-genetic-variation-and-haplotype-diversity-of-cherry-virus-a-from-china
#15
Rui Gao, Yunxiao Xu, Thierry Candresse, Zhen He, Shifang Li, Yuxin Ma, Meiguang Lu
Cherry virus A (CVA) infection appears to be prevalent in cherry plantations worldwide. In this study, the diversity of CVA isolates from 31 cherry samples collected from different orchards around Bohai Bay in northeastern China was analyzed. The complete genome of one of these isolates, ChYT52, was found to be 7,434 nt in length excluding the poly (A) tail. It shares between 79.9-98.7% identity with CVA genome sequences in GenBank, while its RdRp core is more divergent (79.1-90.7% nt identity), likely as a consequence of a recombination event...
2017: PloS One
https://www.readbyqxmd.com/read/28989914/which-components-of-metabolic-syndrome-have-a-greater-effect-on-mortality-cva-and-myocardial-infarction-hyperglycemia-high-blood-pressure-or-both
#16
Alireza Khosravi, Masoumeh Sadeghi, Mehrzad Barghikar
BACKGROUND: This study aims to evaluate the incidence of stroke, ischemic heart disease (IHD), and cardiovascular disease (CVD) mortality in clusters containing hypertension (HTN), clusters containing diabetes (diabetes mellitus [DM]), cluster with both HTN, DM, and cluster without HTN, DM in patients with metabolic syndrome (MetS). MATERIALS AND METHODS: The association between MetS and outcomes was examined in 2257 patients with MetS that were divided into four groups includes patients with MetS with hyperglycemia (Cluster 1), patients with MetS with HTN (Cluster 2), patients with MetS with HTN and hyperglycemia (Cluster 3) and patients with MetS without HTN and hyperglycemia (Cluster 4)...
2017: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28984724/neuro-ophthalmic-manifestations-of-cerebrovascular-accidents
#17
REVIEW
Alaa S Bou Ghannam, Prem S Subramanian
PURPOSE OF REVIEW: Ocular functions can be affected in almost any type of cerebrovascular accident (CVA) creating a burden on the patient and family and limiting functionality. The present review summarizes the different ocular outcomes after stroke, divided into three categories: vision, ocular motility, and visual perception. We also discuss interventions that have been proposed to help restore vision and perception after CVA. RECENT FINDINGS: Interventions that might help expand or compensate for visual field loss and visuospatial neglect include explorative saccade training, prisms, visual restoration therapy (VRT), and transcranial direct current stimulation (tDCS)...
November 2017: Current Opinion in Ophthalmology
https://www.readbyqxmd.com/read/28983441/high-value-care-in-the-evaluation-of-stroke
#18
Prakrity Urja, Eric H Nippoldt, Virginia Barak, Carrie Valenta
Value-based care emphasizes achieving the greatest overall health benefit for every dollar spent. We present an interesting case of stroke, which made us consider how frequently health care providers are utilizing value-based care. A 73-year-old Caucasian, who was initially admitted for a hypertensive emergency, was transferred to our facility for worsening slurring of speech and left-sided weakness. The patient had an extensive chronic cerebrovascular disease, including multiple embolic type strokes, mainly in the distribution of the right temporal-occipital cerebral artery and transient ischemic attacks (TIAs)...
August 1, 2017: Curēus
https://www.readbyqxmd.com/read/28977886/combined-renin-angiotensin-aldosterone-system-blockade-and-statin-therapy-effectively-reduces-the-risk-of-cerebrovascular-accident-in-autosomal-dominant-polycystic-kidney-disease-a-nationwide-population-based-cohort-study
#19
Pei-Hsun Sung, Hsin-Ju Chiang, Mel S Lee, John Y Chiang, Hon-Kan Yip, Yao-Hsu Yang
Fairly limited data reported the incidence and risk of cerebrovascular accident (CVA) in autosomal dominant polycystic kidney disease (ADPKD). Additionally, little is known regarding the therapeutic impact of renin-angiotensin-aldosterone system (RAAS) blockade and statin on reducing the occurrence of CVA in ADPKD. We utilized the data from Taiwan National Health Insurance Research Database (NHIRD) to perform a population-based cohort study (1997-2013). A total of 2,647 patients with ADPKD were selected from 1,000,000 general population after excluding patients with age<18, renal replacement therapy and concomitant diagnosis of CVA...
September 22, 2017: Oncotarget
https://www.readbyqxmd.com/read/28956630/dynamics-of-clinical-recovery-during-the-early-phase-of-rehabilitation-in-patients-with-severe-traumatic-and-non-traumatic-brain-injury
#20
Lydia Oujamaa, Gilles Francony, Perrine Boucheix, Clotilde Schilte, Pierre Bouzat, Dominic Perennou, Jean-Francois Payen
PURPOSE: Our aim was to describe the changes in the functional outcome at the early phase of rehabilitation following severe brain injury and to identify the factors associated with faster recovery. METHODS: This retrospective analysis included 182 patients who were transferred from the intensive care unit (ICU) to a post-ICU neurorehabilitation unit following traumatic brain injury (TBI) (n = 82) or cerebrovascular accident (CVA) (n = 100). Admission, discharge and changes in scores were calculated for the Functional Independent Measurement (FIM) and the Wessex Head Injury Matrix (WHIM)...
2017: Brain Injury: [BI]
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