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https://www.readbyqxmd.com/read/28799299/a-comparative-study-of-csf-viral-rna-loads-between-hiv-positive-patients-with-neurological-manifestations-and-neurologically-asymptomatic-hiv-patients
#1
A D Mathur, S Devesh
INTRODUCTION: There are conflicting reports in literature about correlation of CSF viral RNA levels with neurological manifestations in HIV positive patients. Many studies in animals and human subjects have shown that CSF HIV-1 RNA can be useful as a specific marker of HIV induced neuropathology. To the contrary there are studies which show that neurological disease states can occur in absence of significant increase of CSF HIV RNA. MATERIALS AND METHODS: This was a prospective study conducted at Base hospital Delhi Cantt, New Delhi, a tertiary care hospitals for HIV patients...
August 2017: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/28774437/new-approach-to-detect-and-classify-stroke-in-skull-ct-images-via-analysis-of-brain-tissue-densities
#2
Pedro P Rebouças Filho, Róger Moura Sarmento, Gabriel Bandeira Holanda, Daniel de Alencar Lima
BACKGROUND AND OBJECTIVE: Cerebral vascular accident (CVA), also known as stroke, is an important health problem worldwide and it affects 16 million people worldwide every year. About 30% of those that have a stroke die and 40% remain with serious physical limitations. However, recovery in the damaged region is possible if treatment is performed immediately. In the case of a stroke, Computed Tomography (CT) is the most appropriate technique to confirm the occurrence and to investigate its extent and severity...
September 2017: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/28770251/first-report-of-cherry-virus-a-infecting-prunus-mume-in-south-korea
#3
Seungmo Lim, Davaajargal Igori, Dasom Baek, In-Sook Cho, Gug-Seoun Choi, Jae Sun Moon
We report the detection of cherry virus A (CVA) in a Prunus mume sample using Illumina HiSeq 2500 paired-end RNA sequencing. CVA isolate OC shared highest sequence identity with CVA isolate J, which was recently identified in P. armeniaca in Japan. To the best of our knowledge, this is the first report of CVA infecting P. mume in Korea and the first complete genome sequence of CVA isolated from P. mume in the world.
June 2017: Virusdisease
https://www.readbyqxmd.com/read/28761679/the-safety-efficacy-and-cost-effectiveness-of-stress-echocardiography-in-patients-with-high-pretest-probability-of-coronary-artery-disease
#4
Alexandros Papachristidis, Daniela Cassar Demarco, Damian Roper, Ioannis Tsironis, Michael Papitsas, Jonathan Byrne, Khaled Alfakih, Mark J Monaghan
OBJECTIVE: In this study, we assess the clinical and cost-effectiveness of stress echocardiography (SE), as well as the place of SE in patients with high pretest probability (PTP) of coronary artery disease (CAD). METHODS: We investigated 257 patients with no history of CAD, who underwent SE, and they had a PTP risk score >61% (high PTP). According to the National Institute for Health and Care Excellence guidance (NICE CG95, 2010), these patients should be investigated directly with an invasive coronary angiogram (ICA)...
2017: Open Heart
https://www.readbyqxmd.com/read/28756578/design-and-application-of-a-medication-assessment-tool-for-secondary-prevention-of-stroke
#5
Marise Gauci, Francesca Wirth, Liberato Camilleri, Lilian M Azzopardi, Anthony Serracino-Inglott
Background Optimisation of drug therapy is essential in the care of older persons and may be facilitated by application of medication assessment tools (MATs). Objective To design, psychometrically evaluate and apply an innovative MAT for secondary prevention of ischaemic stroke with particular relevance to older persons. Method Review criteria were selected from clinical practice guidelines and MAT-CVA was developed, validated and tested for reliability and feasibility. MAT-CVA was applied to 150 patients with a diagnosis of ischaemic stroke or transient ischaemic attack admitted to a rehabilitation hospital...
July 29, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28734985/safety-of-catheter-ablation-of-atrial-fibrillation-using-fiber-optic-based-contact-force-sensing
#6
Moussa Mansour, Dhanunjaya Lakkireddy, Douglas Packer, John D Day, Srijoy Mahapatra, Kyle Brunner, Vivek Reddy, Andrea Natale
BACKGROUND: While the body of evidence showing the benefit of contact force (CF)-sensing catheters in improving atrial fibrillation ablation success rate is growing, real-world safety data of this technology are limited. OBJECTIVE: The aim of this study was to report the complication rate in patients undergoing ablation using a specific CF-sensing catheter (TactiCath Quartz CF ablation catheter, Abbott, St. Paul, MN) in a large worldwide database. METHODS: User-reported adverse event data from January 2014 to December 2015 were reviewed for the ablation catheter...
July 20, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28734143/cortical-thickness-changes-in-adult-moyamoya-disease-assessed-by-structural-magnetic-resonance-imaging
#7
Peng-Gang Qiao, Zhi-Wei Zuo, Cong Han, Juan Zhou, Hong-Tao Zhang, Lian Duan, Tianyi Qian, Gong-Jie Li
PURPOSE: To characterize the changes in cortical thickness of adult patients with moyamoya disease (MMD). METHODS: 60 patients with MMD and 60 age and sex-matched healthy volunteers were recruited. Structural images were acquired by MRI. Freesurfer was used to measure cortical thickness in patients and controls, and this was compared with MRA scores and cerebrovascular accident (CVA) scores. RESULTS: Compared with controls, the average cortical thickness of both cerebral hemispheres was lower in patients than in controls and symmetrical differences were seen in the regional cortex: bilateral precentral gyri were thinner, bilateral postcentral gyri and posterior cingulate gyri were thicker, and thinning and thickening were both found in the insula...
July 11, 2017: Clinical Imaging
https://www.readbyqxmd.com/read/28720681/the-eubivas-project-within-and-between-subject-biological-variation-data-for-serum-creatinine-using-enzymatic-and-alkaline-picrate-methods-and-implications-for-monitoring
#8
Anna Carobene, Irene Marino, Abdurrahman Coŝkun, Mustafa Serteser, Ibrahim Unsal, Elena Guerra, William A Bartlett, Sverre Sandberg, Aasne Karine Aarsand, Marit Sverresdotter Sylte, Thomas Røraas, Una Ørvim Sølvik, Pilar Fernandez-Calle, Jorge Díaz-Garzón, Francesca Tosato, Mario Plebani, Niels Jonker, Gerhard Barla, Ferruccio Ceriotti
BACKGROUND: The European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) European Biological Variation Study (EuBIVAS) has been established to deliver rigorously determined biological variation (BV) indices. EuBIVAS determined BV for serum creatinine using the enzymatic and alkaline picrate measurement methods. METHOD: In total, 91 healthy individuals (38 males, 53 females; age range, 21-69 years) were bled for 10 consecutive weeks at 6 European laboratories...
July 18, 2017: Clinical Chemistry
https://www.readbyqxmd.com/read/28718779/a-review-and-experimental-study-on-application-of-classifiers-and-evolutionary-algorithms-in-eeg-based-brain-machine-interface-systems
#9
Farajollah Tahernezhad-Javazm, Vahid Azimirad, Maryam Shoaran
OBJECTIVE: Considering the importance and the near future development of noninvasive Brain-Machine Interface (BMI) systems, this paper presents a comprehensive theoretical-experimental survey on the classification and evolutionary methods for BMI-based systems in which EEG signals are used. APPROACH: The paper is divided into two main parts. In the first part a wide range of different types of the base and combinatorial classifiers including boosting and bagging classifiers and also evolutionary algorithms are reviewed and investigated...
July 18, 2017: Journal of Neural Engineering
https://www.readbyqxmd.com/read/28718683/the-measurement-of-cough-response-to-bronchoconstriction-induced-by-methacholine-inhalation-in-healthy-subjects-an-examination-using-the-astograph-method
#10
Johsuke Hara, Masaki Fujimura, Noriyuki Ohkura, Tamami Sakai, Kenta Yamamura, Miki Abo, Hayato Koba, Satoshi Watanabe, Taro Yoneda, Shingo Nishikawa, Takashi Sone, Hideharu Kimura, Yoshihisa Ishiura, Kazuo Kasahara
BACKGROUND: We demonstrated that heightened cough response to bronchoconstriction is a fundamental feature of cough variant asthma (CVA). To evaluate this physiological feature of CVA in daily clinical practice, it is necessary to clarify the cough response to bronchoconstriction in healthy subjects. We evaluated cough response to methacholine (MCh)-induced bronchoconstriction in healthy subjects. A forced oscillometry technique was used to measure airway resistance changes with Mch. METHODS: Healthy never-smokers (21 men, 20 women; mean 22...
July 18, 2017: Experimental Lung Research
https://www.readbyqxmd.com/read/28713428/clinically-apparent-arterial-thrombosis-in-persons-with-systemic-vasculitis
#11
Alexander Tsoukas, Sasha Bernatsky, Lawrence Joseph, David L Buckeridge, Patrick Bélisle, Christian A Pineau
OBJECTIVE: To estimate the incidence rate of clinically apparent arterial thrombotic events and associated comorbidities in patients with primary systemic vasculitis. METHODS: Using large cohort administrative data from Quebec, Canada, we identified patients with vasculitis, including polyarteritis nodosa (PAN) and granulomatosis with polyangiitis (GPA). Incident acute myocardial infarctions (AMIs) and cerebrovascular accidents (CVAs) after the diagnosis of vasculitis were ascertained in the PAN and GPA group via billing and hospitalization data...
2017: International Journal of Rheumatology
https://www.readbyqxmd.com/read/28712563/trends-in-comorbidity-in-patients-hospitalised-for-cardiovascular-disease
#12
Josefien Buddeke, Michiel L Bots, Ineke van Dis, Anho Liem, Frank L J Visseren, Ilonca Vaartjes
BACKGROUND: We determined trends over time in cardiovascular and non-cardiovascular comorbidity in patients hospitalised for cardiovascular disease (CVD). METHODS: The Dutch nationwide hospital register was used to identify patients hospitalised for CVD during 2000-2010. Comorbidity was defined as a previous hospital admission for CVD other than the index CVD, cancer, diabetes, musculoskeletal and connective tissue disorders, respiratory disorders, thyroid gland disorders, kidney disorders and dementia in the five years previous to hospital admittance for the index CVD...
July 10, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28711910/combined-renin-angiotensin-aldosterone-system-blockade-and-statin-therapy-effectively-reduces-the-risk-of-cerebrovascular-accident-in-autosomal-dominant-polycystic-kidney-disease-a-nationwide-population-based-cohort-study
#13
Pei-Hsun Sung, Hsin-Ju Chiang, Mel S Lee, John Y Chiang, Hon-Kan Yip, Yao-Hsu Yang
Fairly limited data reported the incidence and risk of cerebrovascular accident (CVA) in autosomal dominant polycystic kidney disease (ADPKD). Additionally, little is known regarding the therapeutic impact of renin-angiotensin-aldosterone system (RAAS) blockade and statin on reducing the occurrence of CVA in ADPKD. We utilized the data from Taiwan National Health Insurance Research Database (NHIRD) to perform a population-based cohort study (1997-2013). A total of 2,647 patients with ADPKD were selected from 1,000,000 general population after excluding patients with age<18, renal replacement therapy and concomitant diagnosis of CVA...
June 27, 2017: Oncotarget
https://www.readbyqxmd.com/read/28702118/comparison-of-nutech-functional-score-with-european-stroke-scale-for-patients-with-cerebrovascular-accident-treated-with-human-embryonic-stem-cells-nfs-for-cva-patients-treated-with-hescs
#14
Geeta Shroff
PURPOSE: Stem cell therapy is a promising modality for treatment of patients with chronic cerebrovascular accident (CVA) in whom treatment other than physiotherapy or occupational therapy does not address the repair or recovery of the lost function. In this study, the author aimed at evaluating CVA patients treated with human embryonic stem cell (hESC) therapy and comparing their study outcomes with globally accepted European Stroke Scale (ESS) to that with novel scoring system, Nutech functional score (NFS), a 21-point positional and directional scoring system for assessing patients with CVA...
June 2017: Journal of Vascular and Interventional Neurology
https://www.readbyqxmd.com/read/28698086/stroke-burden-in-rwanda-a-multicenter-study-on-stroke-management-and-outcome
#15
Agabe Emmy Nkusi, Severien Muneza, Steven Nshuti, David Hakizimana, Paulin Munyemana, Menelas Nkeshimana, Emmanuel Rudakemwa, Etienne Amendezo
BACKGROUND: Cerebro-vascular accidents (CVA) or Stroke constitute the second leading cause of mortality worldwide. Low and middle income countries bear most of stroke burden worldwide. The main objective of this study is to determine the burden of stroke in Rwanda. METHODS: This was a prospective observational study done in 2 parts; 6 months baseline data collection and outcome assessment sessions at 1 year. RESULTS: 96 patients were enrolled in our series...
July 8, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28688480/an-intelligent-support-system-for-automatic-detection-of-cerebral-vascular-accidents-from-brain-ct-images
#16
Elmira Hajimani, M G Ruano, A E Ruano
OBJECTIVE: This paper presents a Radial Basis Functions Neural Network (RBFNN) based detection system, for automatic identification of Cerebral Vascular Accidents (CVA) through analysis of Computed Tomographic (CT) images. METHODS: For the design of a neural network classifier, a Multi Objective Genetic Algorithm (MOGA) framework is used to determine the architecture of the classifier, its corresponding parameters and input features by maximizing the classification precision, while ensuring generalization...
July 2017: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/28675629/long-term-follow-up-after-left-atrial-appendage-occlusion-with-comparison-of-transesophageal-echocardiography-vs-computed-tomography-to-guide-medical-therapy-and-data-about-post-closure-cardioversion
#17
Benjamin Berte, Christine Attenhofer Jost, Dominik Maurer, Anja Fäh-Gunz, Xavier Pillois, Barbara Naegeli, Monica Pfyffer, Gabor Sütsch, Christoph Scharf
AIMS: The use of left atrial appendage (LAA)-occluders in atrial fibrillation is increasing. There are few data on the comparison between transesophageal echocardiography (TEE) and computed tomography (MDCT) assessing peridevice-flow and outcome of electrical cardioversion (ECV) in these patients. METHODS AND RESULTS: Single-center prospective registry from 2009 to 2015 including all LAA-occluders to analyze success and complications during implantation and follow-up...
July 4, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28673375/dietary-inflammatory-index-in-relation-to-sub-clinical-atherosclerosis-and-atherosclerotic-vascular-disease-mortality-in-older-women
#18
RANDOMIZED CONTROLLED TRIAL
Nicola P Bondonno, Joshua R Lewis, Lauren C Blekkenhorst, Nitin Shivappa, Richard J Woodman, Catherine P Bondonno, Natalie C Ward, James R Hébert, Peter L Thompson, Richard L Prince, Jonathan M Hodgson
Arterial wall thickening, stimulated by low-grade systemic inflammation, underlies many cardiovascular events. As diet is a significant moderator of systemic inflammation, the dietary inflammatory index (DIITM) has recently been devised to assess the overall inflammatory potential of an individual's diet. The primary objective of this study was to assess the association of the DII with common carotid artery-intima-media thickness (CCA-IMT) and carotid plaques. To substantiate the clinical importance of these findings we assessed the relationship of DII score with atherosclerotic vascular disease (ASVD)-related mortality, ischaemic cerebrovascular disease (CVA)-related mortality and ischaemic heart disease (IHD)-related mortality more...
June 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28671088/correlation-study-of-cough-variant-asthma-and-mycoplasma-pneumonia-infection-in-children
#19
Wen Li, Cunfang Ban, Junxia Zhang, Yingying Hu, Bingjuan Han, Bingchao Han
Cough variant asthma (CVA), as one of bronchitis diseases, features with repeated cough. In clinics, CAV does not show significant abnormal signs, therefore antibiotic therapy can hardly achieve satisfactory treatment effect. With the development of scientific technologies, the correlation between mycoplasma pneumoniae infection and CVA has become a hot research topic in clinics. In clinics, mycoplasma pneumoniae is extensively regarded as major cause for CVA, with complex pathogenic mechanism. The symptoms of CVA is characterized by chronic non abnormal inflammation, normally accompanied with bronchospasm and intestinal infection...
May 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28670999/biological-variation-of-holotranscobalamin-and-cobalamin-in-healthy-individuals
#20
Mette Brokner, Helle Borgstrøm Hager, Morten Lindberg
Data on biological variation for cobalamin and holotranscobalamin (holoTC) are limited. The aim of this study was to determine within-subject (CVI) and between-subject (CVG) biological variations for these analytes in a healthy population. We collected blood samples from 15 healthy volunteers (12 women and three men, 22-66 years) on the same weekday for 10 consecutive weeks. Serum samples were stored at -80 °C until analysis in duplicate in a single analytical run. The CVI and CVG were estimated by nested ANOVA...
July 2, 2017: Scandinavian Journal of Clinical and Laboratory Investigation
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