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https://www.readbyqxmd.com/read/28240005/surgery-for-diverticulitis-in-the-21st-century-recent-evidence
#1
Arden M Morris, Cindy Kin
Sigmoid diverticulitis is an increasingly common disease in Western countries. As technology has led to increased knowledge about the disease and options for treatment, management strategies have become less certain. In previous years, the rationale for early elective surgery was largely preventive, due to concern that diverticulitis recurrence would result in increased risk of sepsis or the need for a colostomy. New technology has enabled diagnosis, through computed tomography scans, predictive information through clinical and administrative databases, and less invasive treatment options, through laparoscopic techniques...
February 24, 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28239999/glioblastoma-multiforme-a-review-of-its-epidemiology-and-pathogenesis-through-clinical-presentation-and-treatment
#2
Farina Hanif, Kanza Muzaffar, Kahkashan Perveen, Saima M Malhi, Shabana U Simjee
Glioblastoma multiforme (GBM) is one of the most malignant types of central nervous system tumors. Despite advances in treatment modalities it remains largely incurable. The objective of our review is to provide a holistic picture of GBM epidemiology, etiology, pathogenesis, clinical findings and treatment. A literature search was conducted for GBM at PubMed and Google Scholar, with relevant key words like glioblastoma multiforme, pathogenesis, signs and symptoms, treatment etc., and papers published until 2015 were reviewed...
1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28239917/decrease-in-mortality-of-adult-epilepsy-patients-since-1980-lessons-learned-from-a-hospital-based-cohort
#3
C A Granbichler, W Oberaigner, G Kuchukhidze, J-P Ndayisaba, A Ndayisaba, A Taylor, G Bauer, G Luef, E Trinka
BACKGROUND AND PURPOSE: Data on mortality in patients with epilepsy have been available since the 1800s. They consistently show a 2-3-fold increase compared to the general population. Despite major advances in diagnostic tools and treatment options, there is no evidence for a decrease in premature deaths. The temporal trend of mortality in a hospital-based epilepsy cohort over three decades was assessed. METHODS: A hospital-based incidence cohort was recruited from a specialized epilepsy outpatient clinic at Innsbruck Medical University between 1980 and 2007, divided by decade into three cohorts and followed for 5 years after initial epilepsy diagnosis...
February 27, 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/28239886/fibrocartilaginous-mesenchymoma-of-bone-a-single-institution-experience-with-molecular-investigations-and-a-review-of-the-literature
#4
M Gambarotti, A Righi, D Vanel, S Cocchi, S Benini, F M Elli, G Mantovani, P Ruggieri, S Boriani, D Donati, M Sbaraglia, A P Dei Tos, P Picci
AIMS: Fibrocartilaginous mesenchymoma is a rare intraosseous lesion with a total of 25 cases described in the literature. This study describes the clinical, radiological, and histological features of eight new cases of fibrocartilaginous mesenchymoma collected at a single institution between 1982 and 2016. The presence of GNAS and IDH1/2 mutations and MDM2 amplification was explored to evaluate possible links between fibrocartilaginous mesenchymoma, fibrous dysplasia, dedifferentiated chondrosarcoma, and low-grade osteosarcoma...
February 26, 2017: Histopathology
https://www.readbyqxmd.com/read/28239880/long-term-use-of-oral-nucleos-t-ide-analogues-for-chronic-hepatitis-b-does-not-increase-cancer-risk-a-cohort-study-of-44-494-subjects
#5
G L-H Wong, Y-K Tse, T C-F Yip, H L-Y Chan, K K-F Tsoi, V W-S Wong
BACKGROUND: Patients with chronic hepatitis B (CHB) need long-term antiviral treatment with nucleos(t)ide analogues (NA). Animal studies suggest that some NA may increase cancer risk, but human data are lacking. AIM: To investigate cancer risks in patients with or without NA treatment. METHODS: We conducted a territory-wide cohort study using the database from Hospital Authority in Hong Kong. The diagnosis of CHB and various malignancies was based on the International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) diagnosis codes between 2000 and 2012...
February 27, 2017: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/28239860/hypovitaminosis-a-in-extensively-grazed-beef-cattle
#6
E M Parker, C P Gardiner, A E Kessell, A J Parker
CASE REPORT: Vitamin A deficiency was diagnosed in a herd of 97 19-month-old Braford heifers in the Mitchell Grass Downs (Astrebla spp.) bioregion of Hughenden in north-western Queensland during November 2015. Two heifers died after a 48-h history of sternal recumbency and of the 19 that had neurological signs, 7 were blind. Histological changes in the optic nerves of the two necropsied cattle were consistent with vitamin A deficiency. This diagnosis was supported by vitamin A concentrations in fresh liver samples of 5 and 6 mg/kg wet tissue (reference range, 100-175 mg/kg) despite treatment of the cattle with twice the recommended dose of parenteral vitamin A 3 weeks prior to sampling...
March 2017: Australian Veterinary Journal
https://www.readbyqxmd.com/read/28239844/spectrum-and-clinical-variants-of-giant-cell-elastolytic-granuloma
#7
Wan-Ting Chen, Pa-Fan Hsiao, Yu-Hung Wu
BACKGROUND: Giant cell elastolytic granuloma, also known as annular elastolytic giant cell granuloma or actinic granuloma, is histologically characterized by elastophagocytosis. Recent studies have revealed various clinical presentations in both sun-exposed and non-sun-exposed areas. OBJECTIVES: To clarify clinical characteristics based on case series observation. METHODS: We retrospectively reviewed patients who fulfilled the pathological diagnosis criteria for giant cell elastolytic granuloma seen at Mackay Memorial Hospital from 2000 to 2014...
February 27, 2017: International Journal of Dermatology
https://www.readbyqxmd.com/read/28239813/ucp2-in-early-diagnosis-and-prognosis-of-sepsis
#8
Z-M Jiang, Q-H Yang, C-Q Zhu
OBJECTIVE: Sepsis, a systemic inflammatory response syndrome caused by infection, is a serious threat to the lives of patients. Sepsis can cause tissue hypoperfusion and septic shock which leads to organ dysfunction and death via a variety of mechanisms. Mitochondrial protein (UCP2) involves in immune response, regulation of oxidative stress, and maintenance of mitochondrial membrane potential as well as energy production. However, the role of UCP2 in sepsis remains to be further explored...
February 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28239741/-impingement-syndromes-of-the-shoulder
#9
M Beirer, A B Imhoff, S Braun
In addition to tears of the rotator cuff, isolated impingement syndrome of the shoulder is the most common diagnosis in shoulder disorders. This is of high relevance in orthopedic sports medicine. In fact, impingement of the shoulder is not the diagnosis but rather a symptom of a functional or even a structural pathology. Detailed knowledge about the different types of impingement and the underlying causes is essential to provide adequate treatment. Primarily, impingement of the shoulder should be treated nonoperatively...
February 26, 2017: Der Orthopäde
https://www.readbyqxmd.com/read/28239595/tuberculosis-of-olfactory-area-a-rare-presentation
#10
Deepak Dalmia, Jeena Pillai, Pankil Shah, Jasleen Kaur
Nasal tuberculosis is a rare clinical entity even in developing countries where tuberculosis of respiratory tract is extremely high. It becomes more difficult to diagnose if it presents with symptoms which are not commonly associated with nasal tuberculosis. Here we report the diagnosis, treatment and follow up of a rare case of primary nasal tuberculosis of olfactory groove region. Early diagnosis and timely treatment will certainly reduce the morbidity of this disease.
March 2017: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/28239594/subluxation-of-the-cricoarytenoid-joint-after-external-laryngeal-trauma-a-rare-case-and-review-of-the-literature
#11
Eviatar Friedlander, Paula Martínez Pascual, Julia Da Costa Belisario, Daniel Poletti Serafini
Cricoarytenoid joint subluxation is rare condition. There are <200 cases reported in the English literature. The most frequent cause of this condition is a traumatic tracheal intubation which account for approximately 80 % of all cases. The most common symptoms are dysphonia and pain of the anterior region of the neck which appear after upper airway manipulation or cervical trauma. In this report we present a well-documented case of a 31 year old male that was referred to the outpatient clinic because of acute dysphonia and pain that appeared immediately after receiving a blow of a soccer ball...
March 2017: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/28239572/study-of-ulcero-membranous-lesions-of-tonsil-in-an-indian-scenario
#12
D Sridhar Reddy, A Shoban Babu, J B S Rathod, Ch Sravan Kumar, S Rajesh
'Ulcero-membranous lesions over tonsil' is a special entity, which puzzles every physician and surgeon because of it's diverse etiology. Every insult to the tonsil heals by ulcer and later membrane formation. A retrospective study has been conducted at our institute to analyse the cases of ulcero-membranous lesions of tonsil in terms of etiology, clinical features, diagnosis, treatment protocols and outcome in an Indian context. Diphtheria, if not detected early and treated, can lead to significant morbidity and mortality because of critical complications...
March 2017: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/28239567/value-of-routine-dengue-diagnosis-in-endemic-countries
#13
REVIEW
James Ayukepi Ayukekbong, Olufunmilayo G Oyero, Samuel Ekpesu Nnukwu, Henry Nzike Mesumbe, Cajetang Nkong Fobisong
Dengue is one of the most common arthropod-borne viral diseases in humans and it is a leading cause of illness and death in the tropical and subtropical regions of the world. It is thought to account for 400 million cases annually among approximately 3.97 billion people at risk of infection in 128 endemic countries. Despite the global prevalence of the disease, the availability of a vaccine is limited in most countries in the endemic areas. Most endemic countries in South America, South East Asia and Africa serve as attractive touristic sites for people from non-endemic countries who become infected and export the virus to dengue-free regions...
February 12, 2017: World Journal of Virology
https://www.readbyqxmd.com/read/28239542/a-case-of-mixed-dust-pneumoconiosis-with-desquamative-interstitial-pneumonia-like-reaction-in-an-aluminum-welder
#14
Yuki Iijima, Masashi Bando, Hideaki Yamasawa, Hiroshi Moriyama, Tamiko Takemura, Toshiro Niki, Yukihiko Sugiyama
A 60-year-old man presented with an 18-month history of gradually worsening cough and a 12-month history of dyspnea on exertion. High-resolution computed tomography showed bilateral uniform ground grass opacity in the lower lung fields, partially resolved by smoking cessation. A tentative diagnosis of desquamative interstitial pneumonia (DIP) was made. Video-assisted thoracic surgery was performed and pathological analysis showed peribronchiolar fibrosis with intra-alveolar macrophage infiltration. Elemental analysis detected aluminum and iron in the upper lobe and only iron in the lower lobe...
2017: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/28239539/metabolic-syndrome-s-risk-factors-and-its-association-with-nutritional-status-in-schoolchildren
#15
Fabiana Costa Teixeira, Flavia Erika Felix Pereira, Avany Fernandes Pereira, Beatriz Gonçalves Ribeiro
The metabolic risk factors (RF) to the diagnosis of metabolic syndrome (MetS) have been evidenced at early ages, including children. The aim of the present study was to identify the prevalence of RF to the diagnosis of MetS and its association with nutritional status of schoolchildren from 6 to 10 years old. A cross-sectional study was carried out in 505 students of municipal schools in Macae, Brazil, conducted from 2013 to 2014. The RF evaluated were: blood pressure (mm Hg), triglycerides (mmol/L), HDL-cholesterol (mmol/L) fasting glucose (mmol/L) and waist circumference (cm)...
June 2017: Preventive Medicine Reports
https://www.readbyqxmd.com/read/28239520/association-of-vitamin-d-status-and-clinical-and-radiological-outcomes-in-a-treated-ms-population-in-poland
#16
Sławomir Wawrzyniak, Emilia Mikołajewska, Ewelina Kuczko-Piekarska, Anna Niezgodzińska-Maciejek, Aleksander Goch
BACKGROUND: Vitamin D influences the immune system significantly. Previous studies have found that vitamin D deficiency in adolescence can play a significant role in increasing the risk of developing autoimmune diseases including multiple sclerosis. The aim of this study was to investigate the relationship between the vitamin D status in serum and clinical and radiological outcomes in a treated population in Poland. METHODS: Inclusion criteria met 83 adult patients aged 20-61 years with diagnosis of relapsing-remitting multiple sclerosis, who underwent immunomodulatory treatment which lasted at least 12 months...
February 2017: Brain and Behavior
https://www.readbyqxmd.com/read/28239496/life-expectancy-in-pleural-and-peritoneal-mesothelioma
#17
Robert Shavelle, Kate Vavra-Musser, Jessica Lee, Jordan Brooks
Background. Mesothelioma is a rare cancer with a historically dire prognosis. We sought to calculate life expectancies for patients with pleural or peritoneal mesothelioma, both at time of diagnosis and several years later, and to examine whether survival has improved in recent years. Methods. Data on 10,258 pleural and 1,229 peritoneal patients from the SEER US national cancer database, 1973-2011, were analyzed using the Cox proportional hazards regression model. Results. The major factors related to survival were age, sex, stage, grade, histology, and treatment...
2017: Lung Cancer International
https://www.readbyqxmd.com/read/28239462/thrombocytopenia-in-patients-with-melanoma-receiving-immune-checkpoint-inhibitor-therapy
#18
Eileen Shiuan, Kathryn E Beckermann, Alpaslan Ozgun, Ciara Kelly, Meredith McKean, Jennifer McQuade, Mary Ann Thompson, Igor Puzanov, John P Greer, Suthee Rapisuwon, Michael Postow, Michael A Davies, Zeynep Eroglu, Douglas Johnson
BACKGROUND: Immune checkpoint inhibitors, including antibodies against programmed death 1 (PD-1) and cytotoxic T-lymphocyte antigen 4 (CTLA-4), are being used with increasing frequency for the treatment of cancer. Immune-related adverse events (irAEs) including colitis, dermatitis, and pneumonitis are well described, but less frequent events are now emerging with larger numbers of patients treated. Herein we describe the incidence and spectrum of thrombocytopenia following immune checkpoint inhibitor therapy and two severe cases of idiopathic thrombocytopenic purpura (ITP)...
2017: Journal for Immunotherapy of Cancer
https://www.readbyqxmd.com/read/28239407/the-greek-orthodox-version-of-the-brief-religious-coping-b-rcope-instrument-psychometric-properties-in-three-samples-and-associations-with-mental-disorders-suicidality-illness-perceptions-and-quality-of-life
#19
Vassiliki Paika, Elias Andreoulakis, Elisavet Ntountoulaki, Dimitra Papaioannou, Konstantinos Kotsis, Vassiliki Siafaka, Konstantinos N Fountoulakis, Kenneth I Pargament, Andre F Carvalho, Thomas Hyphantis
BACKGROUND: The B-RCOPE is a brief measure assessing religious coping. We aimed to assess the psychometric properties of its Greek version in people with and without long-term conditions (LTCs). Associations between religious coping and mental illness, suicidality, illness perceptions, and quality of life were also investigated. METHODS: The B-RCOPE was administered to 351 patients with diabetes, chronic pulmonary obstructive disease (COPD), and rheumatic diseases attending either the emergency department (N = 74) or specialty clinics (N = 302) and 127 people without LTCs...
2017: Annals of General Psychiatry
https://www.readbyqxmd.com/read/28239361/deictic-and-propositional-meaning-new-perspectives-on-language-in-schizophrenia
#20
Vitor C Zimmerer, Stuart Watson, Douglas Turkington, I Nicol Ferrier, Wolfram Hinzen
Emerging linguistic evidence points at disordered language behavior as a defining characteristic of schizophrenia. In this article, we review this literature and demonstrate how a framework focusing on two core functions of language-reference and propositional meaning-can conceptualize schizophrenic symptoms, identify important variables for risk assessment, diagnosis, and treatment, and inform cognitive behavioral therapy and other remedial approaches. We introduce the linguistic phenomena of deictic anchoring and propositional complexity, explain how they relate to schizophrenic symptoms, and show how they can be tracked in language behavior...
2017: Frontiers in Psychiatry
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