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Nicola Cellini
In recent years sleep-related memory consolidation has become a central topic in the sleep research field. Several studies have shown that in healthy individuals sleep promotes memory consolidation. Notwithstanding this, the consequences of sleep disorders on offline memory consolidation remain poorly investigated. Research studies indicate that patients with insomnia, obstructive sleep apnea, and narcolepsy often exhibit sleep-related impairment in the consolidation of declarative and procedural information...
September 25, 2016: Sleep Medicine Reviews
Judith Owens, Margaret Weiss, Earl Nordbrock, Greg Mattingly, Sharon Wigal, Laurence L Greenhill, Wei-Wei Chang, Ann Childress, Robert J Kupper, Akwete Adjei
OBJECTIVE: To evaluate measures of sleep (exploratory endpoints) in two pivotal studies of a multilayer bead extended-release methylphenidate (MPH-MLR) treatment of attention-deficit/hyperactivity disorder in children. METHODS: Study 1 evaluated the time course of response to MPH-MLR (n = 26) patients in an analog classroom setting through four phases: screening (≤28 days), open label (OL) dose optimization (4 weeks), double-blind (DB) crossover (2 weeks; placebo vs...
October 18, 2016: Journal of Child and Adolescent Psychopharmacology
Youngsin Jung, Erik K St Louis
REM sleep behavior disorder (RBD) is a common parasomnia disorder affecting between 1 and 7 % of community-dwelling adults, most frequently older adults. RBD is characterized by nocturnal complex motor behavior and polysomnographic REM sleep without atonia. RBD is strongly associated with synucleinopathy neurodegeneration. The approach to RBD management is currently twofold: symptomatic treatment to prevent injury and prognostic counseling and longitudinal follow-up surveillance for phenoconversion toward overt neurodegenerative disorders...
November 2016: Current Treatment Options in Neurology
Vincent Mysliwiec, Matthew S Brock, Brian O'Reilly, Bernard J Roth, Anne Germain
No abstract text is available yet for this article.
October 10, 2016: Sleep
N A Amosova, I G Smolentseva, P M Guseinova, O A Maslyuk, E L Gavrilov
Disorders of sleep and wakefulness occur in about 60-98% of patients with Parkinson's disease (PD). The majority of research on the scale and nature of the disorders was performed in patients treated with antiparkinsonian drugs, and, therefore, the true picture of sleep disorders was interfering with side effects of therapy. The spectrum of these disorders in PD patients is broad and includes insomnia, parasomnia and hypersomnia. The main symptoms of insomnia are difficulty in maintaining sleep, associated with nocturia, rapid eye movement (REM) sleep behavior disorder (RBD), night cramps, akinesia and tremor...
2016: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
O A Gan'kina, E E Vasenina, O S Levin, E Yu Fedotova, S N Illarioshkin
Parkinson's disease (PD) is a common neurodegenerative disease. Literature sources indicate the association of PD and mutations in the glucocerebrosidase A (GBA) gene. According to our study, the frequency of the two most common mutations in the GBA gene, N370S and L444P, is 1.85%. Mutation carriers have slower progression of motor symptoms, but are more likely to develop drug-induced motor fluctuations and dyskinesia. In carriers of GBA mutations, the severity of cognitive impairment corresponds to age-matched patients without mutations...
2016: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
Shery Goril, Dora Zalai, Louise Scott, Colin M Shapiro
OBJECTIVES: Caregivers describe significant sleep disturbances in the vast majority of children and adolescents, which is diagnosed as fetal alcohol spectrum disorders (FASD), but objective data on sleep disorders in this population are almost completely lacking. Animal models suggest that intrauterine alcohol exposure may disrupt sleep wake patterns, cause sleep fragmentation, and specifically affect the suprachiasmatic nucleus, thus disrupting melatonin secretion. The objective of this pioneering study was to evaluate sleep and melatonin abnormalities in children with FASD using objective, gold-standard measures...
July 2016: Sleep Medicine
Nuria Matos, Alex Iranzo, Carles Gaig, Joan Santamaria
No abstract text is available yet for this article.
July 2016: Sleep Medicine
Kiran Maski, Judith A Owens
Sleep problems are frequently encountered as presenting complaints in child neurology clinical practice. They can affect the functioning and quality of life of children, particularly those with primary neurological and neurodevelopmental disorders, since coexisting sleep problems can add substantially to neurocognitive and behavioural comorbidities. Additionally, symptoms of some sleep disorders such as parasomnias and narcolepsy can be confused with those of other neurological disorders (eg, epilepsy), posing diagnostic challenges for paediatric neurologists...
October 2016: Lancet Neurology
Nicolas Ribeiro, Yannick Gounden, Véronique Quaglino
Lucid dreaming (LD) is a state of consciousness in which the dreamer is aware that he or she is dreaming and can possibly control the content of his or her dream. To investigate the LD prevalence among different samples, researchers have used different types of methodologies. With regard to retrospective self-report questionnaire, two ways of proceeding seem to emerge. In one case, a definition of LD is given to participants ("During LD, one is-while dreaming-aware of the fact that one is dreaming. It is possible to deliberately wake up, to control the dream action, or to observe passively the course of the dream with this awareness"), while in the other instances, participants are presented separate questions targeting specific LD indicators (dream awareness and dream control)...
2016: Frontiers in Psychology
Güzin Mukaddes Sevinçer, Gökben Hızlı Sayar
Sleep-related eating disorder (SRED) is a parasomnia characterised by recurrent episodes of eating after arousal from sleep, occurring in an unconscious and involuntary manner. It has been reported mainly in association with the use of psychotropic medications. This case report is of a patient diagnosed with a sleep-related eating disorder associated with amnesia in the postoperative period following bariatric surgery. Such eating episodes without awareness in postoperative period might have devastating results by disturbing compliance with suggested eating behaviours...
September 7, 2016: Obesity Research & Clinical Practice
W Vaughn McCall, Ruth M Benca, Peter B Rosenquist, Mary Anne Riley, Laryssa McCloud, Jill C Newman, Doug Case, Meredith Rumble, Andrew D Krystal
OBJECTIVE: Insomnia is associated with increased risk for suicide. The Food and Drug Administration (FDA) has mandated that warnings regarding suicide be included in the prescribing information for hypnotic medications. The authors conducted a review of the evidence for and against the claim that hypnotics increase the risk of suicide. METHOD: This review focused on modern, FDA-approved hypnotics, beginning with the introduction of benzodiazepines, limiting its findings to adults...
September 9, 2016: American Journal of Psychiatry
Rexford Muza, Madeleine Lawrence, Panagis Drakatos
PURPOSE OF REVIEW: The purpose of this review is to help further the understanding of the clinical profile of patients with sexsomnia and to better understand the spectrum of the clinical manifestations of sexsomnia. We will review the literature from the past decade on the subject and then compare it with our own clinical experience from patients who were retrospectively identified with sexsomnia at a tertiary sleep clinic over a 6-year period. RECENT FINDINGS: The prevalence of sexual behaviours in sleep remains unknown, but it seems to involve predominantly younger male adults who also frequently exhibit other non-rapid eye movement-related parasomnias...
November 2016: Current Opinion in Pulmonary Medicine
M Urrutia-Pereira, D Solé, H J Chong Neto, V Acosta, A M Cepeda, M Álvarez-Castelló, C F Almendarez, J Lozano-Saenz, J C Sisul-Alvariza, N A Rosario, A J Castillo, M Valentin-Rostan, H Badellino, R L Castro-Almarales, M González-León, C Sanchez-Silot, M M Avalos, C Fernandez, F Berroa, M M De la Cruz, R O S Sarni
BACKGROUND: Asthma and/or allergic rhinitis have been associated with sleep disorders. The aim of this study was to evaluate sleep disorders in Latin-American children (4-10 years) from nine countries, with persistent asthma (A) and/or allergic rhinitis (AR) and in normal controls (C). METHODS: Parents from 454 C children and 700 A and/or AR children followed up in allergy reference clinics completed the Children's Sleep Habits Questionnaire (CSHQ) which is a retrospective one-week questionnaire composed of 33 questions composed of seven subscales (bedtime resistance, sleep duration, sleep anxiety, night wakings, parasomnias, sleep-disordered breathing and daytime sleepiness)...
September 1, 2016: Allergologia et Immunopathologia
Marlena Hupalo, Janusz W Smigielski, Dariusz J Jaskolski
PURPOSE: To find the optimal duration of the long-term video-EEG (LTM) and assess diagnostics utility of LTM in patients with epilepsy and other paroxysmal events in terms of future diagnosis and management. METHODS: Retrospective analysis of 282 LTMs performed in the last 5 years in our Epilepsy Monitoring Unit (EMU), in 202 consecutive patients. The analysis included demographic data, monitoring time, number and type of paroxysmal events, the time until their onset, influence of LTM result on the diagnosis and future management...
2016: Neurologia i Neurochirurgia Polska
José Luiz Pedroso, Pedro Braga-Neto, Alberto R M Martinez, Carlos R Martins, Flávio M Rezende Filho, Manoel A Sobreira-Neto, Lucila B F Prado, Gilmar F do Prado, Marcondes C França, Orlando G P Barsottini
PURPOSE OF REVIEW: This article provides a description on clinical features and pathophysiology of the main sleep disorders observed in Machado-Joseph disease (MJD). RECENT FINDINGS: Pathological studies have clearly demonstrated that degenerative process in MJD is widespread in the nervous system, and not restricted to the cerebellum. Nonmotor manifestations are frequent and may include pain, cramps, dysautonomia, cognitive deficits, psychiatric manifestations, olfactory deficits, fatigue, nutritional issues, and sleep disorders...
November 2016: Current Opinion in Psychiatry
Antonio Perciaccante, Alessia Coralli
No abstract text is available yet for this article.
September 2016: Lancet Neurology
Carlo Cipolli, Michele Ferrara, Luigi De Gennaro, Giuseppe Plazzi
Recent advances in electrophysiological [e.g., surface high-density electroencephalographic (hd-EEG) and intracranial recordings], video-polysomnography (video-PSG), transcranial stimulation and neuroimaging techniques allow more in-depth and more accurate investigation of the neural correlates of dreaming in healthy individuals and in patients with brain-damage, neurodegenerative diseases, sleep disorders or parasomnias. Convergent evidence provided by studies using these techniques in healthy subjects has led to a reformulation of several unresolved issues of dream generation and recall [such as the inter- and intra-individual differences in dream recall and the predictivity of specific EEG rhythms, such as theta in rapid eye movement (REM) sleep, for dream recall] within more comprehensive models of human consciousness and its variations across sleep/wake states than the traditional models, which were largely based on the neurophysiology of REM sleep in animals...
July 28, 2016: Sleep Medicine Reviews
Mohammad Torabi-Nami, Samrad Mehrabi, Sabri Derman
Sleep-related movement disorders should be differentiated from parasomnias, sleep-associated behavioral disorders, and epilepsy. Polysomnography (PSG) is the gold standard in evaluating such disorders. Periodic leg movement disorder during sleep (PLMS), hypnic jerks, bruxism, rhythmic movement disorder, restless legs syndrome, and nocturnal leg cramps have broadly been discussed in the literature. However, periodic arm movement disorder in sleep (PAMS) is a less-appreciated entity perhaps because arm surface electromyography is not an integral part of the standard polysomnography...
July 2016: Basic and Clinical Neuroscience
Julia Heller, Nikolina Brcina, Imis Dogan, Florian Holtbernd, Sandro Romanzetti, Jörg B Schulz, Johannes Schiefer, Kathrin Reetz
Idiopathic rapid eye movement (REM) sleep behavior disorder (RBD) is a parasomnia characterized by the loss of physiological atonia of skeletal muscles with abnormal behavior during dream sleep. RBD may be the initial manifestation of neurodegenerative diseases, particularly of α-synucleinopathies such as Parkinson's disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy (MSA). However, gauging the individual risk of subsequent phenoconversion and making assumptions on the type of disease that may subsequently follow RBD is challenging...
June 25, 2016: Sleep Medicine Reviews
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