Huachun Zou, Zhen Lu, Wenjia Weng, Ligang Yang, Luoyao Yang, Xinying Leng, Junfeng Wang, Yi-Fan Lin, Jiaxin Wu, Leiwen Fu, Xiaohui Zhang, Yuwei Li, Liuyuan Wang, Xinsheng Wu, Xinyi Zhou, Tian Tian, Lixia Huang, Christina M Marra, Bin Yang, Tian-Ci Yang, Wujian Ke
BACKGROUND: The ability to accurately identify the absolute risk of neurosyphilis diagnosis for patients with syphilis would allow preventative and therapeutic interventions to be delivered to patients at high-risk, sparing patients at low-risk from unnecessary care. We aimed to develop, validate, and evaluate the clinical utility of simplified clinical diagnostic models for neurosyphilis diagnosis in HIV-negative patients with syphilis. METHODS: We searched PubMed, China National Knowledge Infrastructure and UpToDate for publications about neurosyphilis diagnostic guidelines in English or Chinese from database inception until March 15, 2023...
August 2023: EClinicalMedicine