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Acquired Immune Deficiency Syndrome

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https://www.readbyqxmd.com/read/27914221/prevalence-of-trypanosoma-cruzi-hiv-coinfection-in-southern-brazil
#1
Dulce Stauffert, Mariangela Freitas da Silveira, Marília Arndt Mesenburg, Adriane Brod Manta, Alessandra da Silva Dutra, Guilherme Lucas de Oliveira Bicca, Marcos Marreiro Villela
Chagas disease reactivation has been a defining condition for acquired immune deficiency syndrome in Brazil for individuals coinfected with Trypanosoma cruzi and HIV since 2004. Although the first coinfection case was reported in the 1980s, its prevalence has not been firmly established. In order to know coinfection prevalence, a cross-sectional study of 200 HIV patients was performed between January and July 2013 in the city of Pelotas, in southern Rio Grande do Sul, an endemic area for Chagas disease. Ten subjects were found positive for T...
November 30, 2016: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/27904599/elimination-of-mother-to-child-transmission-of-human-immunodeficiency-virus-and-syphilis-in-cuba-a-stepping-stone-toward-acquired-immune-deficiency-syndrome-free-generation
#2
Saurabh R Shrivastava, Prateek S Shrivastava, Jegadeesh Ramasamy
No abstract text is available yet for this article.
2016: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/27890948/study-of-infections-among-human-immunodeficiency-virus-acquired-immunodeficiency-syndrome-patients-in-shadan-hospital-telangana-india
#3
Sukumar Gajjala Reddy, Syed Yousuf Ali, Azheel Khalidi
BACKGROUND: Human immunodeficiency virus (HIV) pandemicity is a major concern today as it causes greater loss of productivity than any other disease. HIV infection leads to profound immune deficiency and patients become highly susceptible to opportunistic infections (OIs). HIV epidemic in India is heterogeneous in nature, both in terms of routes of transmission as well as geographical spread. AIMS: (1) Determine prevalence of OIs among HIV-seropositive patients and their relation to CD4 count and to focus on the routes of transmission...
July 2016: Indian Journal of Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/27876685/efficacy-of-mobile-serious-games-in-increasing-hiv-risk-perception-in-swaziland-a-randomized-control-trial-sgprev-trial-research-protocol
#4
Bhekumusa Wellington Lukhele, Patou Musumari, Christina El-Saaidi, Teeranee Techasrivichien, S Pilar Suguimoto, Masako Ono Kihara, Masahiro Kihara
BACKGROUND: The human immunodeficiency virus (HIV) and acquired immune deficiency syndrome (AIDS) continue to be a major public health problem in Sub-Saharan Africa (SSA), particularly in Swaziland, which has the highest HIV prevalence in this region. A wide range of strategies and interventions have been used to promote behavior change, though almost all such interventions have involved mass media. Therefore, innovative behavior change strategies beyond mass media communication are urgently needed...
November 22, 2016: JMIR Research Protocols
https://www.readbyqxmd.com/read/27872774/pulmonary-kaposi-sarcoma-an-uncommon-cause-of-respiratory-failure-in-the-era-of-highly-active-antiretroviral-therapy-case-report-and-review-of-the-literature
#5
Stanley M Nwabudike, Stefan Hemmings, Yonette Paul, Yordanis Habtegebriel, Octavius Polk, Alem Mehari
Kaposi Sarcoma (KS) is the most common malignancy associated with Acquired Immune Deficiency Syndrome (AIDS) and is caused by Human Herpesvirus 8 (HHV 8) or Kaposi Sarcoma Herpesvirus (KSHV). In about 90% of cases Kaposi Sarcoma is associated with cutaneous lesions; however visceral disease can occur in the absence of cutaneous involvement. In the era of Highly Active Antiretroviral Therapy (HAART), the incidence of KS has declined. Clinical features of pulmonary KS might be difficult to distinguish from pneumonia in the immunocompromised patients and could lead to diagnostic challenges...
2016: Case Reports in Infectious Diseases
https://www.readbyqxmd.com/read/27869733/antiviral-therapy-by-hiv-1-broadly-neutralizing-and-inhibitory-antibodies
#6
REVIEW
Zhiqing Zhang, Shaowei Li, Ying Gu, Ningshao Xia
Human immunodeficiency virus type 1 (HIV-1) infection causes acquired immune deficiency syndrome (AIDS), a global epidemic for more than three decades. HIV-1 replication is primarily controlled through antiretroviral therapy (ART) but this treatment does not cure HIV-1 infection. Furthermore, there is increasing viral resistance to ART, and side effects associated with long-term therapy. Consequently, there is a need of alternative candidates for HIV-1 prevention and therapy. Recent advances have discovered multiple broadly neutralizing antibodies against HIV-1...
November 18, 2016: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/27867916/impact-of-human-immunodeficiency-virus-in-the-pathogenesis-and-outcome-of-patients-with-glioblastoma-multiforme
#7
Winward Choy, Carlito Lagman, Seung J Lee, Timothy T Bui, Michael Safaee, Isaac Yang
BACKGROUND: Improvement in antiviral therapies have been accompanied by an increased frequency of non-Acquired Immune Deficiency Syndrome (AIDS) defining malignancies, such as glioblastoma multiforme. Here, we investigated all reported cases of human immunodeficiency virus (HIV)-positive patients with glioblastoma and evaluated their clinical outcomes. A comprehensive review of the molecular pathogenetic mechanisms underlying glioblastoma development in the setting of HIV/AIDS is provided...
October 2016: Brain Tumor Research and Treatment
https://www.readbyqxmd.com/read/27862500/antibodies-to-h1-histone-from-the-sera-of-hiv-infected-patients-recognize-and-catalyze-site-specific-degradation-of-this-histone
#8
Svetlana V Baranova, Pavel S Dmitrienok, Nikita V Ivanisenko, Valentina N Buneva, Georgy A Nevinsky
Histones and their posttranslational modifications have key roles in chromatin remodeling and gene transcription. Besides intranuclear functions, histones act as damage-associated molecules when they are released into the extracellular space. Administration of histones to animals leads to systemic inflammatory and toxic responses. Autoantibodies with enzymatic activities (abzymes) are distinctive feature of some autoimmune and viral diseases. Electrophoretically and immunologically homogeneous IgGs containing no canonical enzymes were isolated from sera of human immunodeficiency virus-infected patients by chromatography on several affinity sorbents...
November 10, 2016: Journal of Molecular Recognition: JMR
https://www.readbyqxmd.com/read/27858869/switch-of-predicted-hiv-1-tropism-in-treated-subjects-and-its-association-with-disease-progression
#9
Antonella Castagna, Laura Monno, Stefania Carta, Laura Galli, Stefania Carrara, Valentina Fedele, Grazia Punzi, Iuri Fanti, Pietro Caramello, Alessandro Cozzi Lepri, Andrea De Luca, Francesca Ceccherini-Silberstein, Antonella d'Arminio Monforte
Dynamics of human immunodeficiency virus type 1 (HIV-1) tropism after antiretroviral therapy (ART) initiation and their association with disease progression are poorly investigated.This was a cohort study on subjects from the ICONA cohort receiving ART with persistently detectable (PD) or persistently undetectable (PU) viral load (VL) and with stored plasma or peripheral blood mononuclear cell (PBMC) samples at 2 time-points (T1, T2) after ART initiation. HIV-1 co-receptor tropism was determined by V3-loop sequencing and the geno2pheno algorithm...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27846873/a-cross-sectional-survey-of-hiv-transmission-and-behavior-among-men-who-have-sex-with-men-in-different-areas-of-inner-mongolia-autonomous-region-china
#10
Lin Qu, Wenrui Wang, Yongming Gao, Jingyuan Yang, Jijiang Dai, Dawei Wang, Bo Tao
BACKGROUND: Little research has been conducted on the human immunodeficiency virus (HIV) epidemic and the sexual intercourse habits of men who have sex with men (MSM) in crowded places, both locally and abroad. This study conducted a survey of MSM in different locales of Inner Mongolia to provide a reference for developing strategies or measures to prevent and control HIV among this understudied population. METHODS: We conducted a cross-sectional survey of men aged 18 years and older at different venues popular among MSM in Inner Mongolia...
November 15, 2016: BMC Public Health
https://www.readbyqxmd.com/read/27844017/design-of-new-potent-htlv-1-protease-inhibitors-in-silico-study
#11
Mitra Kheirabadi, Javad Maleki, Safieh Soufian, Samaneh Hosseini
HTLV-1 and HIV-1 are two major causes for severe T-cell leukemia disease and acquired immune deficiency syndrome (AIDS). HTLV-1 protease, a member of aspartic acid protease family, plays important roles in maturation during virus replication cycle. The impairment of these proteases results in uninfectious HTLV-1virions.Similar to HIV-1protease deliberate mutations that confer drug resistance on HTLV-1 are frequently seen in this protease. Therefore, inhibition of HTLV-1 protease activity is expected to disrupt HTLV-1's ability to replicate and infect additional cells...
March 2016: Molecular Biology Research Communications
https://www.readbyqxmd.com/read/27835623/gonorrhea-control-united-states-1972-2015-a-narrative-review
#12
Thomas A Peterman, Kevin O'Connor, Heather M Bradley, Elizabeth A Torrone, Kyle T Bernstein
Gonorrhea is the second most commonly reported infection. It can lead to pelvic inflammatory disease, ectopic pregnancy, and infertility. Rates of gonorrhea decreased after the National Gonorrhea Control Program began in 1972, but stabilized in the mid 1990s. The emergence of antimicrobial resistant strains increases the urgency for enhanced gonorrhea control efforts. To identify possible approaches for improving gonorrhea control, we reviewed historic protocols, reports, and other documents related to the activities of the National Gonorrhea Control Program using Centers for Disease Control and Prevention records and the published literature...
December 2016: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/27833967/diagnosing-hiv-associated-cerebral-diseases-the-importance-of-neuropathology-in-understanding-hiv
#13
Ioan Alexandru Diaconu, LaurenŢiu MihăiŢă Stratan, Luciana Nichita, Victoria Aramă, Valentina Ruxandra Moroti Constantinescu, Alexandra Ioana Diaconu, Daniela Adriana Ion
The study aims to compare two aspects concerning the diagnosis of acquired immune deficiency syndrome (AIDS)-associated central nervous system (CNS) pathology (neuroAIDS): clinical diagnoses issued ante mortem with pathology results issued post mortem. The group of 39 human immunodeficiency virus (HIV)-positive patients was created over 23 years and is limited by marked heterogeneity. The enrolled cases were treated at the "Prof. Dr. Matei Bals" National Institute for Infectious Diseases, Bucharest, Romania, deceased due to AIDS-related complications and underwent brain necropsies performed in the Pathology Laboratory at the "Colentina" Clinical Hospital, Bucharest...
2016: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/27832150/one-year-tuberculosis-risk-in-rheumatoid-arthritis-patients-starting-their-first-tumor-necrosis-factor-inhibitor-therapy-from-2008-to-2012-in-taiwan-a-nationwide-population-based-cohort-study
#14
Chong-Hong Lim, Ching-Heng Lin, Der-Yuan Chen, Yi-Ming Chen, Wen-Cheng Chao, Tsai-Ling Liao, Hsin-Hua Chen
OBJECTIVE: To investigate the risk of tuberculosis (TB) among rheumatoid arthritis (RA) patients within 1 year after initiation of tumor necrosis factor inhibitor (TNFi) therapy from 2008 to 2012. METHODS: We used the 2003-2013 Taiwanese National Health Insurance Research Database to identify RA patients who started any RA-related medical therapy from 2008 to 2012. Those who initiated etanercept or adalimumab therapy during 2008-2012 were selected as the TNFi group and those who never received biologic disease-modifying anti-rheumatic drug therapy were identified as the comparison group after excluding the patients who had a history of TB or human immunodeficiency virus infection/acquired immune deficiency syndrome...
2016: PloS One
https://www.readbyqxmd.com/read/27830031/human-immunodeficiency-virus-hiv-is-highly-associated-with-giant-idiopathic-esophageal-ulcers-in-acquired-immunodeficiency-syndrome-aids-patients
#15
Bei Lv, Xin Cheng, Jackson Gao, Hong Zhao, Liping Chen, Liwei Wang, Shaoping Huang, Zhenyu Fan, Renfang Zhang, Yinzhong Shen, Lei Li, Baochi Liu, Tangkai Qi, Jing Wang, Jilin Cheng
OBJECTIVE: This study aimed to determine whether the human immunodeficiency virus (HIV) exists in giant idiopathic esophageal ulcers in the patients with acquired immune deficiency syndrome (AIDS). METHODS: 16 AIDS patients with a primary complaint of epigastric discomfort were examined by gastroscopy. Multiple and giant esophageal ulcers were biopsied and analyzed with pathology staining and reverse transcription-polymerase chain reaction (RT-PCR) to determine the potential pathogenic microorganisms, including HIV, cytomegalovirus (CMV) and herpes simplex viruses (HSV)...
2016: American Journal of Translational Research
https://www.readbyqxmd.com/read/27829381/seroprevalence-of-hepatitis-c-virus-among-people-living-with-hiv-aids-in-latin-america-and-the-caribbean-a-systematic-review
#16
Fatima Mitiko Tengan, Karim Yakub Ibrahim, Bianca Peixoto Dantas, Caroline Manchiero, Mariana Cavalheiro Magri, Wanderley Marques Bernardo
BACKGROUND: Studies have shown that the immunosuppression induced by the human immunodeficiency virus (HIV) accelerates the natural history of liver disease associated with hepatitis C virus (HCV), with 3- to 5-fold higher odds of coinfected individuals developing cirrhosis. However, estimates of the seroprevalence of hepatitis C among people living with HIV/acquired immune deficiency syndrome (AIDS) (PLHA) in Latin America and the Caribbean (LAC) are widely variable. METHODS: We performed a systematic review to estimate the seroprevalence of HCV among PLHA...
November 9, 2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27826056/prognosis-of-patients-with-chronic-hepatitis-b-in-france-2008-2013-a-nationwide-observational-and-hospital-based-study
#17
Vincent Mallet, Kamal Hamed, Michaël Schwarzinger
BACKGROUND AND AIMS: How risk factors associated with chronic hepatitis B (CHB) modify liver disease progression and mortality has been scarcely reported outside of Asia. METHODS: All individuals discharged with CHB from acute and post-acute care hospitals in Metropolitan France between January 2008 and December 2013 were selected. Associations between liver- and non-liver-related risk factors and both liver disease progression (end-stage liver disease or hepatocellular carcinoma) and mortality were assessed by multivariate Cox proportional hazard models...
November 5, 2016: Journal of Hepatology
https://www.readbyqxmd.com/read/27818966/sexually-transmitted-infections-among-hospitalized-patients-with-human-immunodeficiency-virus-infection-and-acquired-immune-deficiency-syndrome-hiv-aids-in-zahedan-southeastern-iran
#18
Seyed Mohammad Hashemi-Shahri, Batool Sharifi-Mood, Hamid-Reza Kouhpayeh, Javad Moazen, Mohsen Farrokhian, Masoud Salehi
BACKGROUND: Studies show that nearly 40 million people are living with human immunodeficiency virus infection and acquired immune deficiency syndrome (HIV/AIDS) around the world and since the beginning of the epidemic, about 35 million have died from AIDS. Heterosexual intercourse is the most common route for transmission of HIV infection (85%). People with a sexually transmitted infection (STI), such as syphilis, genital herpes, chancroid, or bacterial vaginosis, are more likely to obtain HIV infection during sex...
September 2016: International Journal of High Risk Behaviors & Addiction
https://www.readbyqxmd.com/read/27800523/invasive-aspergillus-sinusitis-in-human-immunodeficiency-virus-infection-case-report-and-review-of-the-literature
#19
REVIEW
John M Humphrey, Thomas J Walsh, Roy M Gulick
Invasive Aspergillus (IA) sinusitis is a life-threatening opportunistic infection in immunocompromised individuals, but it is uncommon in human immunodeficiency virus (HIV) infection. To gain a better understanding of the characteristics of IA sinusitis in this population, we present a unique case of chronic IA sinusitis in an HIV-infected patient taking antiretroviral therapy and review the literature summarizing published cases of invasive aspergillosis of the paranasal (n = 41) and mastoid (n = 17) sinuses in HIV-infected individuals...
September 2016: Open Forum Infectious Diseases
https://www.readbyqxmd.com/read/27795876/a-study-of-parasitic-and-bacterial-pathogens-associated-with-diarrhea-in-hiv-positive-patients
#20
Siddharth Shah, Vaishali Kongre, Varun Kumar, Renu Bharadwaj
INTRODUCTION: Diarrhea is a common complication of acquired immune deficiency syndrome (AIDS), occurring in almost 90% of AIDS patients in developing countries like India. The present study was aimed to determine the prevalence and microbiological profile of pathogens associated with diarrhea in human immunodeficiency virus (HIV) positive patients and their relation to CD4 counts. MATERIALS AND METHODS: Forty-five successive HIV-positive patients, 27 with diarrhea (study group) and 18 without diarrhea (control group), were included in the three-month study...
September 27, 2016: Curēus
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