keyword
MENU ▼
Read by QxMD icon Read
search

Deprescribing

keyword
https://www.readbyqxmd.com/read/28220380/effectiveness-of-interventions-to-deprescribe-inappropriate-proton-pump-inhibitors-in-older-adults
#1
REVIEW
Tom D Wilsdon, Ivanka Hendrix, Tilenka R J Thynne, Arduino A Mangoni
BACKGROUND: The use of proton pump inhibitors (PPIs) in older adults is high, often inappropriate, and may cause harm. Deprescribing is defined as the reduction, withdrawal, or discontinuation of inappropriate medication. OBJECTIVE: We conducted a systematic review to determine the effectiveness of interventions to deprescribe inappropriate PPIs in older adults. METHODS: We searched MEDLINE, PubMed, Embase, the Cochrane Library, ProQuest Dissertations and Theses Global, and Google from inception to January 2017 for randomized and non-randomized studies describing the outcomes of interventions to deprescribe inappropriate PPIs in older adults (mean or median age of ≥65 years)...
February 21, 2017: Drugs & Aging
https://www.readbyqxmd.com/read/28214150/self-efficacy-for-deprescribing-a-survey-for-health-care-professionals-using-evidence-based-deprescribing-guidelines
#2
Barbara Farrell, Lisa Richardson, Lalitha Raman-Wilms, David de Launay, Mhd Wasem Alsabbagh, James Conklin
BACKGROUND: Although polypharmacy is associated with significant morbidity, deprescribing can be challenging. In particular, clinicians express difficulty with their ability to deprescribe (i.e. reduce or stop medications that are potentially inappropriate). Evidence-based deprescribing guidelines are designed to help clinicians take action on reducing or stopping medications that may be causing more harm than benefit. OBJECTIVES: Determine if implementation of evidence-based guidelines increases self-efficacy for deprescribing proton pump inhibitor (PPI), benzodiazepine receptor agonist (BZRA) and antipsychotic (AP) drug classes...
January 28, 2017: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/28184303/deprescribing-medicines-in-the-acute-setting-to-reduce-the-risk-of-falls
#3
Vanessa Marvin, Emily Ward, Alan J Poots, Katie Heard, Arvind Rajagopalan, Barry Jubraj
BACKGROUND: Falls are a common cause of morbidity and hospitalisation in older people. Inappropriate prescribing and polypharmacy contribute to falls risk in elderly patients. This study's aim was to quantify the problem and find out if medication review in the hospital setting led to deprescribing of medicines associated with falls risk. METHODS: Admissions records for elderly patients were examined to identify those whose presenting complaint included a fall. Inpatient medication charts, pharmaceutical care notes, medical notes and discharge summaries were examined to identify any falls-risk medicines from admission histories and to determine if any medication review took place, and whether or not changes were made as a result...
January 2017: European Journal of Hospital Pharmacy. Science and Practice
https://www.readbyqxmd.com/read/28143413/use-of-the-empower-brochure-to-deprescribe-sedative-hypnotic-drugs-in-older-adults-with-mild-cognitive-impairment
#4
Philippe Martin, Cara Tannenbaum
BACKGROUND: Evidence-based mailed educational brochures about the harms of sedative-hypnotic use lead to discontinuation of chronic benzodiazepine use in older adults. It remains unknown whether patients with mild cognitive impairment (MCI) are able to understand the information in the EMPOWER brochures, and whether they achieve similar rates of benzodiazepine discontinuation. METHODS: Post-hoc analysis of the EMPOWER randomized, double-blind, wait-list controlled trial that assessed the effect of a direct-to-consumer educational intervention on benzodiazepine discontinuation...
January 31, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28119312/stoppfrail-screening-tool-of-older-persons-prescriptions-in-frail-adults-with-limited-life-expectancy-consensus-validation
#5
Amanda Hanora Lavan, Paul Gallagher, Carole Parsons, Denis O'Mahony
OBJECTIVE: to validate STOPPFrail, a list of explicit criteria for potentially inappropriate medication (PIM) use in frail older adults with limited life expectancy. DESIGN: a Delphi consensus survey of an expert panel comprising academic geriatricians, clinical pharmacologists, palliative care physicians, old age psychiatrists, general practitioners and clinical pharmacists. SETTING: Ireland. SUBJECTS: seventeen panellists...
January 23, 2017: Age and Ageing
https://www.readbyqxmd.com/read/28091333/an-ecological-approach-to-reducing-potentially-inappropriate-medication-use-canadian-deprescribing-network
#6
Cara Tannenbaum, Barbara Farrell, James Shaw, Steve Morgan, Johanna Trimble, Jane Currie, Justin Turner, Paula Rochon, James Silvius
Polypharmacy is growing in Canada, along with adverse drug events and drug-related costs. Part of the solution may be deprescribing, the planned and supervised process of dose reduction or stopping of medications that may be causing harm or are no longer providing benefit. Deprescribing can be a complex process, involving the intersection of patients, health care providers, and organizational and policy factors serving as enablers or barriers. This article describes the justification, theoretical foundation, and process for developing a Canadian Deprescribing Network (CaDeN), a network of individuals, organizations, and decision-makers committed to promoting the appropriate use of medications and non-pharmacological approaches to care, especially among older people in Canada...
January 16, 2017: Canadian Journal on Aging, la Revue Canadienne du Vieillissement
https://www.readbyqxmd.com/read/28063660/deprescribing-a-narrative-review-of-the-evidence-and-practical-recommendations-for-recognizing-opportunities-and-taking-action
#7
REVIEW
Emily Reeve, Wade Thompson, Barbara Farrell
Deprescribing can be defined as the process of withdrawal or dose reduction of medications which are considered inappropriate in an individual. The aim of this narrative review is to provide an overview of "deprescribing"; firstly discussing the potential benefits and harms followed by the barriers to and enablers of deprescribing. We also provide practical recommendations to recognise opportunities and strategies for deprescribing in practice. Studies focused on minimizing polypharmacy indicate that deprescribing may be associated with potential benefits including resolution of adverse drug reactions, improved quality of life and medication adherence and a reduction in drug costs...
March 2017: European Journal of Internal Medicine
https://www.readbyqxmd.com/read/28059976/deprescribing-in-child-and-adolescent-psychiatry-a-sorely-needed-intervention
#8
EDITORIAL
Eugene Grudnikoff, Christopher Bellonci
No abstract text is available yet for this article.
January 2017: American Journal of Therapeutics
https://www.readbyqxmd.com/read/28032332/deprescribing-implications-for-the-anaesthetist
#9
EDITORIAL
J Hermanowski, N Levy, P Mills, N Penfold
No abstract text is available yet for this article.
December 29, 2016: Anaesthesia
https://www.readbyqxmd.com/read/27984921/deprescribing-a-new-goal-focused-on-the-patient
#10
Jorge Enrique Machado-Alba, Andrés Gaviria-Mendoza, Manuel Enrique Machado-Duque, Laura Chica
It is estimated that one-fifth of adult patients are treated with polypharmacy (five or more drugs) and the prevalence of this phenomenon in the elderly is even higher, ranging from 30% to 70%, even reaching 90% in residents of residential aged care facilities. Polypharmacy in the elderly increases the risk of adverse reactions, inappropriate prescriptions, drug interactions, number of hospitalizations, costs, and even death. In a recent systematic review, the authors proposed defining deprescribing as 'the process of withdrawal of inappropriate medication supervised by a health care professional with the goal of managing polypharmacy and improving outcomes'...
December 26, 2016: Expert Opinion on Drug Safety
https://www.readbyqxmd.com/read/27981503/lack-of-evidence-to-guide-deprescribing-of-antihyperglycemics-a-systematic-review
#11
REVIEW
Cody D Black, Wade Thompson, Vivian Welch, Lisa McCarthy, Carlos Rojas-Fernandez, Heather Lochnan, Salima Shamji, Ross Upshur, Barbara Farrell
INTRODUCTION: Individualizing glycemic targets to goals of care and time to benefit in persons with type 2 diabetes is good practice, particularly in populations at risk of hypoglycemia and adverse outcomes relating to the use of antihyperglycemics. Guidelines acknowledge the need for relaxed targets in frail older adults, but there is little guidance on how to safely deprescribe (i.e. stop, reduce or substitute) antihyperglycemics. METHODS: The purpose of this study was to synthesize evidence from all studies evaluating the effects of deprescribing versus continuing antihyperglycemics in older adults with type 2 diabetes...
February 2017: Diabetes Therapy: Research, Treatment and Education of Diabetes and related Disorders
https://www.readbyqxmd.com/read/27965033/medication-management-policy-practice-and-research-in-australian-residential-aged-care-current-and-future-directions
#12
Janet K Sluggett, Jenni Ilomäki, Karla L Seaman, Megan Corlis, J Simon Bell
Eight percent of Australians aged 65 years and over receive residential aged care each year. Residents are increasingly older, frailer and have complex care needs on entry to residential aged care. Up to 63% of Australian residents of aged care facilities take nine or more medications regularly. Together, these factors place residents at high risk of adverse drug events. This paper reviews medication-related policies, practices and research in Australian residential aged care. Complex processes underpin prescribing, supply and administration of medications in aged care facilities...
February 2017: Pharmacological Research: the Official Journal of the Italian Pharmacological Society
https://www.readbyqxmd.com/read/27935150/trends-in-potentially-inappropriate-medication-prescribing-to-nursing-home-patients-comparison-of-three-cross-sectional-studies
#13
Kjell H Halvorsen, Geir Selbaek, Sabine Ruths
PURPOSE: The aim of this study was to examine trends in potentially inappropriate medication (PIM) prescribing in Norwegian nursing homes. METHODS: Patients aged ≥70 years were included from three cross-sectional studies conducted in 1997, 2005 and 2011. PIMs were analyzed according to the Norwegian General Practice-Nursing Home criteria (NORGEP-NH), use of single substances to avoid, combinations to avoid, and deprescribing items. Associations between sample and use of PIMs were examined by logistic regression, adjusted for age, gender, and ward...
December 9, 2016: Pharmacoepidemiology and Drug Safety
https://www.readbyqxmd.com/read/27932208/a-novel-approach-to-deprescribing-in-long-term-care-settings-the-smart-campaign
#14
Kathleen Abrahamson, Arif Nazir, Karis Pressler
There have been numerous calls within the medical community urging providers to consider the complex problem of inappropriate polypharmacy and inappropriate medication use among nursing home residents. It is clear that innovative, longitudinal policy-supported interventions are needed to better understand prescribing practices in long-term care settings and to curtail the negative, cascading outcomes associated with inappropriate polypharmacy among elderly patients. The Indiana Safer Medication Administration Regimens and Treatment (SMART) campaign is funded by the Indiana State Department of Health for a pilot period of 2 years (2016-18) with the objectives of: 1...
November 30, 2016: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/27836926/new-horizons-the-management-of-hypertension-in-people-with-dementia
#15
REVIEW
Jennifer Kirsty Harrison, Veronika Van Der Wardt, Simon Paul Conroy, David J Stott, Tom Dening, Adam Lee Gordon, Pip Logan, Tomas James Welsh, Jaspal Taggar, Rowan Harwood, John R F Gladman
The optimal management of hypertension in people with dementia is uncertain. This review explores if people with dementia experience greater adverse effects from antihypertensive medications, if cognitive function is protected or worsened by controlling blood pressure (BP) and if there are subgroups of people with dementia for whom antihypertensive therapy is more likely to be harmful. Robust evidence is scant, trials of antihypertensive medications have generally excluded those with dementia. Observational data show changes in risk association over the life course, with high BP being a risk factor for cognitive decline in mid-life, while low BP is predictive in later life...
November 2016: Age and Ageing
https://www.readbyqxmd.com/read/27814691/factors-influencing-deprescribing-for-residents-in-advanced-care-facilities-insights-from-general-practitioners-in-australia-and-sweden
#16
Beata Borgström Bolmsjö, Anna Palagyi, Lisa Keay, Jan Potter, Richard I Lindley
BACKGROUND: General Practitioners (GPs) are responsible for primary prescribing decisions in most settings. Elderly patients living in Advanced Care Facilities (ACFs) often have significant co-morbidities to consider when selecting an appropriate drug therapy. Careful assessment is required when considering appropriate medication use in frail older patients as they have multiple diseases and thus multiple medication. Many physicians seem reluctant to discontinue other physicians' prescriptions, resulting in further polypharmacy...
November 5, 2016: BMC Family Practice
https://www.readbyqxmd.com/read/27805712/deprescribing-to-reduce-medication-use-will-this-help-your-patient
#17
Robert H Howland
Polypharmacotherapy is a commonly used, but frequently criticized, clinical practice. Deprescribing is the process of discontinuing inappropriate or unnecessary medications, with the goals of decreasing adverse events and drug-drug interactions, simplifying medication regimens to enhance adherence, and reducing costs associated with medication use while maintaining or improving clinical outcomes. Studies of groups of patients suggest that deprescribing medication is feasible and safe, but individual experiences are masked by group data...
November 1, 2016: Journal of Psychosocial Nursing and Mental Health Services
https://www.readbyqxmd.com/read/27805456/deprescribing-321
#18
Jennifer Pruskowski
No abstract text is available yet for this article.
February 2017: Journal of Palliative Medicine
https://www.readbyqxmd.com/read/27785734/development-and-validation-of-the-revised-patients-attitudes-towards-deprescribing-rpatd-questionnaire-versions-for-older-adults-and-caregivers
#19
Emily Reeve, Lee-Fay Low, Sepehr Shakib, Sarah N Hilmer
BACKGROUND: Knowledge of consumer (patient and caregiver) attitudes is essential for conducting medication optimization in practice. OBJECTIVES: The aim of this study was to develop and validate a questionnaire to capture older adults' and caregivers' beliefs and attitudes towards deprescribing. METHODS: The previously validated Patients' Attitudes Towards Deprescribing (PATD) questionnaire was expanded based on literature review, expert opinion and focus groups, and a caregivers' version was developed...
December 2016: Drugs & Aging
https://www.readbyqxmd.com/read/27663392/community-dwelling-older-people-s-attitudes-towards-deprescribing-in-canada
#20
Caroline Sirois, Nicole Ouellet, Emily Reeve
BACKGROUND: While there is evidence that supervised withdrawal of inappropriate medications might be beneficial for individuals with polypharmacy, little is known about their attitudes towards deprescribing. OBJECTIVE: This study aimed to describe the situation among older community-dwelling Canadians. METHODS: A self-administered survey was adapted from the Patients' Attitudes Towards Deprescribing questionnaire and distributed to 10 community pharmacies and 2 community centers...
August 31, 2016: Research in Social & Administrative Pharmacy: RSAP
keyword
keyword
13465
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"