keyword
MENU ▼
Read by QxMD icon Read
search

Smell, olfaction, olfactory

keyword
https://www.readbyqxmd.com/read/29792162/overlapping-but-distinct-topology-for-zebrafish-v2r-like-olfactory-receptors-reminiscent-of-odorant-receptor-spatial-expression-zones
#1
Gaurav Ahuja, Vera Reichel, Daniel Kowatschew, Adnan S Syed, Aswani Kumar Kotagiri, Yuichiro Oka, Franco Weth, Sigrun I Korsching
BACKGROUND: The sense of smell is unrivaled in terms of molecular complexity of its input channels. Even zebrafish, a model vertebrate system in many research fields including olfaction, possesses several hundred different olfactory receptor genes, organized in four different gene families. For one of these families, the initially discovered odorant receptors proper, segregation of expression into distinct spatial subdomains within a common sensory surface has been observed both in teleost fish and in mammals...
May 23, 2018: BMC Genomics
https://www.readbyqxmd.com/read/29767353/influences-of-temporal-lobe-epilepsy-and-temporal-lobe-resection-on-olfaction
#2
Richard L Doty, Isabelle Tourbier, Jessica K Neff, Jonathan Silas, Bruce Turetsky, Paul Moberg, Taehoon Kim, John Pluta, Jaqueline French, Ashwini D Sharan, Michael J Sperling, Natasha Mirza, Anthony Risser, Gordon Baltuch, John A Detre
Although temporal lobe epilepsy (TLE) and resection (TLR) impact olfactory eloquent brain structures, their influences on olfaction remain enigmatic. We sought to more definitively assess the influences of TLE and TLR on olfaction using three well-validated olfactory tests and measuring  the tests' associations with the volume of numerous temporal lobe brain structures. The University of Pennsylvania Smell Identification Test and an odor detection threshold test were administered to 71 TLE patients and 71 age- and sex-matched controls; 69 TLE patients and controls received an odor discrimination/memory test...
May 16, 2018: Journal of Neurology
https://www.readbyqxmd.com/read/29763790/the-language-of-smell-connecting-linguistic-and-psychophysical-properties-of-odor-descriptors
#3
Georgios Iatropoulos, Pawel Herman, Anders Lansner, Jussi Karlgren, Maria Larsson, Jonas K Olofsson
The olfactory sense is a particularly challenging domain for cognitive science investigations of perception, memory, and language. Although many studies show that odors often are difficult to describe verbally, little is known about the associations between olfactory percepts and the words that describe them. Quantitative models of how odor experiences are described in natural language are therefore needed to understand how odors are perceived and communicated. In this study, we develop a computational method to characterize the olfaction-related semantic content of words in a large text corpus of internet sites in English...
May 12, 2018: Cognition
https://www.readbyqxmd.com/read/29762752/variability-and-coupling-of-olfactory-identification-and-episodic-memory-in-older-adults
#4
Jamie E Knight, David A Bennett, Andrea M Piccinin
Objectives: To determine whether assessment-to-assessment fluctuations in episodic memory (EM) reflect fluctuations in olfaction over time. Methods: Within-person coupled variation in EM and the Brief Smell Identification Test (BSIT) was examined in 565 participants aged 58-106 with autopsy data from the Rush Memory and Aging Project. A growth model for up to 15 years of EM data, with BSIT as time-varying covariate, was estimated accounting for main effects of sex, education, ε4 allele, and Alzheimer's disease (AD) pathology, BSIT and time-varying BSIT, as well as the interaction between AD pathology and time-varying BSIT...
May 14, 2018: Journals of Gerontology. Series B, Psychological Sciences and Social Sciences
https://www.readbyqxmd.com/read/29756687/comparing-the-sniffing-behavior-of-great-apes
#5
Susann Jänig, Brigitte M Weiß, Anja Widdig
The importance of smell in humans is well established but we know little about it in regard to our closest relatives, the great apes, as systematic studies on their olfactory behavior are still lacking. Olfaction has long been considered to be of lesser importance in hominids given their relatively smaller olfactory bulbs, fewer functional olfactory receptor genes than other species and absence of a functional vomeronasal organ. Therefore, the aim of this study was to evaluate the use of olfaction in hominids...
May 14, 2018: American Journal of Primatology
https://www.readbyqxmd.com/read/29673427/assessment-of-olfactory-perception-in-individuals-with-motion-sickness
#6
Laurence Jacquot, Jean-Louis Millot, Aurore Colette Paillard
BACKGROUND: Individuals who experience motion sickness (MS) frequently mention the presence of smells in the environment as a factor favoring the occurrence of MS symptoms. The aim of the present work was to compare olfactory function in MS sensitive (MS+) and insensitive (MS-) subjects. METHODS: Olfactory testing included determination of odor detection thresholds, subjective evaluation of the quality (intensity, hedonicity, and familiarity) of three different odorants (limonene, isovaleric acid, and petrol) as well as measures of skin conductance responses to these three odorants...
May 1, 2018: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/29658205/reduced-suprathreshold-odor-identification-in-patients-with-pseudotumor-cerebri-a-non-randomized-prospective-study
#7
Gad Dotan, Eyal Cohen, Ainat Klein, Anat Kesler
BACKGROUND: Recent evidence suggests that olfaction is impaired in patients with pseudotumor cerebri (PTC). OBJECTIVES: To measure suprathreshold olfactory function by using the University of Pennsylvania Smell Identification Test (UPSIT), assessing its usefulness for routine clinical use. METHODS: Forty PTC patients underwent USPIT olfactory testing. RESULTS: Twenty-nine out of 40 (73%) PTC patients (36 women, 4 men; mean age 34 years) had reduced suprathreshold smell sensation according to UPSIT scores: 19 (47%) had mild microsmia, 9 (23%) had moderate microsmia, and one (3%) was classified as having severe microsmia...
January 2018: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/29652815/olfactory-dysfunction-as-a-global-biomarker-for-sniffing-out-alzheimer-s-disease-a-meta-analysis
#8
Alisha M Kotecha, Angelo D C Corrêa, Kim M Fisher, Jo V Rushworth
Cases of Alzheimer's disease (AD) are rising exponentially due to increasing global life expectancy. There are approximately 50 million sufferers worldwide, with prevalence rising most rapidly in low-income countries such as Africa and Asia. There is currently no definite diagnosis of AD until after death, thus an early biomarker for AD is urgently required in order to administer timelier and more effective interventions. Olfactory dysfunction (problems with the sense of smell) is one of the earliest, preclinical symptoms observed in AD...
April 13, 2018: Biosensors
https://www.readbyqxmd.com/read/29651421/when-the-nose-doesn-t-know-canine-olfactory-function-associated-with-health-management-and-potential-links-to-microbiota
#9
REVIEW
Eileen K Jenkins, Mallory T DeChant, Erin B Perry
The impact of health, management, and microbiota on olfactory function in canines has not been examined in review. The most important characteristic of the detection canine is its sense of smell. Olfactory receptors are primarily located on the ethmoturbinates of the nasal cavity. The vomeronasal organ is an additional site of odor detection that detects chemical signals that stimulate behavioral and/or physiological changes. Recent advances in the genetics of olfaction suggest that genetic changes, along with the unique anatomy and airflow of the canine nose, are responsible for the macrosmia of the species...
2018: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/29605223/olfactory-function-and-neurocognitive-outcomes-in-old-age-the-atherosclerosis-risk-in-communities-neurocognitive-study
#10
Priya Palta, Honglei Chen, Jennifer A Deal, A Richey Sharrett, Alden Gross, David Knopman, Michael Griswold, Gerardo Heiss, Thomas H Mosley
INTRODUCTION: We tested the hypothesis that poor sense of smell is associated with lower cognitive function and higher mild cognitive impairment (MCI) prevalence. METHODS: Olfaction, measured by the Sniffin' Sticks test, was categorized as olfactory impairment (OI) (score ≤6) or no OI (score >6). MCI was adjudicated based on review of a neuropsychological examination. Linear regression estimated the mean difference in cognitive factor scores, and log-binomial regression quantified MCI prevalence among participants with versus without OI...
March 29, 2018: Alzheimer's & Dementia: the Journal of the Alzheimer's Association
https://www.readbyqxmd.com/read/29599658/sensory-disruption-in-modern-living-and-the-emergence-of-sensory-inequities
#11
REVIEW
Kara C Hoover
Modern lifestyles are disrupting the human senses-primarily sight, sound, and smell. Noise-induced hearing loss has been noted for centuries and increasing over time following the industrial era. From the mid-20th century, the numbers of individuals with myopia (the leading visual impairment) have been increasing globally. Historical evidence for olfactory dysfunction is not known but its etiological links to pollution suggest it increased following industrialization. Clinical interventions for sight and sound loss include preventative and corrective measures but none exist for olfactory dysfunction...
March 2018: Yale Journal of Biology and Medicine
https://www.readbyqxmd.com/read/29569385/taste-impairment-in-chronic-rhinosinusitis
#12
Florence Othieno, Rodney J Schlosser, Nicholas R Rowan, Kristina A Storck, Jose L Mattos, Timothy L Smith, Zachary M Soler
BACKGROUND: Though many patients with chronic rhinosinusitis (CRS) describe disturbances in smell and taste, there have been no studies specifically assessing taste impairment in CRS. This study sought to objectively assess taste dysfunction in CRS patients and determine whether taste impairment correlates with olfactory dysfunction. Additionally, this investigation sought to determine the impact of taste dysfunction on quality of life (QOL) in CRS and identify the clinical factors that influence taste...
March 23, 2018: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/29548954/effects-of-subthalamic-stimulation-on-olfactory-function-in-parkinson-disease
#13
Rubens Gisbert Cury, Margarete de Jesus Carvalho, Fernando Jeyson Lopez Lasteros, Alice Estevo Dias, Maria Gabriela Dos Santos Ghilardi, Anderson Rodrigues Brandão Paiva, Artur Martins Coutinho, Carlos Alberto Buchpiguel, Manoel J Teixeira, Egberto Reis Barbosa, Erich Talamoni Fonoff
BACKGROUND: Olfactory dysfunction is a nonmotor symptom of Parkinson disease (PD) associated with reduction in quality of life. There is no evidence on whether improvements in olfaction after subthalamic deep brain stimulation (STN-DBS) may be directly attributable to motor improvement or whether this reflects a direct effect of DBS on olfactory brain areas. The aim of the present study was to evaluate the effect of DBS on olfactory function in PD, as well as to explore the correlation between these changes and changes in motor symptoms and brain metabolism...
March 14, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29532253/transcriptional-and-epigenetic-control-of-mammalian-olfactory-epithelium-development
#14
REVIEW
Godwin Sokpor, Eman Abbas, Joachim Rosenbusch, Jochen F Staiger, Tran Tuoc
The postnatal mammalian olfactory epithelium (OE) represents a major aspect of the peripheral olfactory system. It is a pseudostratified tissue that originates from the olfactory placode and is composed of diverse cells, some of which are specialized receptor neurons capable of transducing odorant stimuli to afford the perception of smell (olfaction). The OE is known to offer a tractable miniature model for studying the systematic generation of neurons and glia that typify neural tissue development. During OE development, stem/progenitor cells that will become olfactory sensory neurons and/or non-neuronal cell types display fine spatiotemporal expression of neuronal and non-neuronal genes that ensures their proper proliferation, differentiation, survival, and regeneration...
March 12, 2018: Molecular Neurobiology
https://www.readbyqxmd.com/read/29504772/a-ball-is-not-a-kong-odor-representation-and-search-behavior-in-domestic-dogs-canis-familiaris-of-different-education
#15
Juliane Bräuer, Julia Belger
There has been a growing interest in the cognitive skills of domestic dogs, but most current knowledge about dogs' understanding of their environment is limited to the visual or auditory modality. Although it is well known that dogs have an excellent olfactory sense and that they rely on olfaction heavily when exploring the environment or recognizing individuals, it remains unclear whether dogs perceive odors as representing specific objects. In the current study, we examined this aspect of dogs' perception of the world...
May 2018: Journal of Comparative Psychology
https://www.readbyqxmd.com/read/29497258/odorant-binding-proteins-a-key-player-in-the-sense-of-smell
#16
Govindaraju Archunan
Olfaction is an important mechanism by which humans and animals communicate with environment. Odorant-binding proteins (OBPs) play crucial role in the olfactory mechanism. Here, we briefly discuss about the role of OBPs and their importance in industrial, pest management and therapeutic developments.
2018: Bioinformation
https://www.readbyqxmd.com/read/29488006/olfactory-cleft-evaluation-a-predictor-for-olfactory-function-in-smell-impaired-patients
#17
Sophia C Poletti, Gustavo Murta, Antje Hähner, Thomas Hummel
OBJECTIVE: In this study, we introduce an extension of previous work by Soler et al. (Int Forum Allergy Rhinol 6(3):293-298, 2016) on a modified endoscopic scoring system of the Lund-Kennedy Score (focusing on the olfactory cleft) to evaluate its correlation with the olfactory function in patients with various smell disorders. STUDY DESIGN: A prospective cohort study. METHODS: Two-hundred and eighty-eight participants were included and categorized in five groups according to the cause of their olfactory disorder: (0) control, (1) idiopathic, (2) sino-nasal, (3) postinfectious and (4) post traumatic olfactory loss...
May 2018: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29435824/psycholinguistic-variables-matter-in-odor-naming
#18
John L A Huisman, Asifa Majid
People from Western societies generally find it difficult to name odors. In trying to explain this, the olfactory literature has proposed several theories that focus heavily on properties of the odor itself but rarely discuss properties of the label used to describe it. However, recent studies show speakers of languages with dedicated smell lexicons can name odors with relative ease. Has the role of the lexicon been overlooked in the olfactory literature? Word production studies show properties of the label, such as word frequency and semantic context, influence naming; but this field of research focuses heavily on the visual domain...
February 12, 2018: Memory & Cognition
https://www.readbyqxmd.com/read/29397144/individual-significance-of-olfaction-a-comparison-between-normosmic-and-dysosmic-people
#19
Julia Murr, Thomas Hummel, Gerhard Ritschel, Ilona Croy
BACKGROUND: Olfactory dysfunction is common in older individuals. The importance of such dysfunction to individuals is highly variable: many people do not seem to care about their olfactory dysfunction, others suffer and complain about problems in daily life, a reduced quality of life, or symptoms of depression. OBJECTIVE: Understanding the importance of olfaction for different age groups in normosmic as well as in smell-disordered subjects may help to find reasons for insufficient coping with olfactory dysfunction...
December 5, 2017: Psychosomatics
https://www.readbyqxmd.com/read/29360225/olfactory-dysfunction-and-cognition-among-older-adults-in-the-united-states
#20
Janet S Choi, Kevin Hur, Michael Chow, Jasper Shen, Bozena Wrobel
BACKGROUND: In this work we assess the association between olfactory dysfunction and cognition in a nationally representative sample of older adults in the United States. METHODS: Participants aged ≥60 years (n = 1236) from the 2013-2014 National Health and Nutritional Examination Survey underwent both olfactory and cognitive testing. Olfaction was assessed by both objective test (8-odor Pocket Smell Test: smell impairment defined as score ≤2) and self-report...
January 23, 2018: International Forum of Allergy & Rhinology
keyword
keyword
13456
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"