keyword
MENU ▼
Read by QxMD icon Read
search

Smell, olfaction, olfactory

keyword
https://www.readbyqxmd.com/read/28447155/fine-tuned-evaluation-of-olfactory-function-in-patients-operated-for-nasal-polyposis
#1
Marie-Hortense Sonnet, Duc Trung Nguyen, Phi-Linh Nguyen-Thi, Fabien Arous, Roger Jankowski, Cécile Rumeau
Given the forced-choice procedure of the identification test, patients with profound anosmia are more likely to have higher identification scores by chance than patients with hyposmia or normosmia. This may be a confusing factor when assessing the sense of smell, which alters the appreciation of real olfaction improvement. The aim of this study was to fine-tune the results of the identification Sniffin' Sticks test before and 6 weeks after surgery using the real identification score. A total of 133 patients underwent the Identification (I) and Threshold (T) tests the day before and 6 weeks after nasalization surgery...
April 26, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28410055/olfactory-recognition-based-on-eeg-gamma-band-activity
#2
Onder Aydemir
There are various kinds of brain monitoring techniques, including local field potential, near-infrared spectroscopy, magnetic resonance imaging (MRI), positron emission tomography, functional MRI, electroencephalography (EEG), and magnetoencephalography. Among those techniques, EEG is the most widely used one due to its portability, low setup cost, and noninvasiveness. Apart from other advantages, EEG signals also help to evaluate the ability of the smelling organ. In such studies, EEG signals, which are recorded during smelling, are analyzed to determine the subject lacks any smelling ability or to measure the response of the brain...
April 14, 2017: Neural Computation
https://www.readbyqxmd.com/read/28379355/neuromodulation-in-chemosensory-pathways
#3
Jeremy C McIntyre, Nicolas Thiebaud, John P McGann, Takaki Komiyama, Markus Rothermel
Interactions with the environment depend not only on sensory perception of external stimuli but also on processes of neuromodulation regulated by the internal state of an organism. These processes allow regulation of stimulus detection to match the demands of an organism influenced by its general brain state (satiety, wakefulness/sleep state, attentiveness, arousal, learning etc.). The sense of smell is initiated by sensory neurons located in the nasal cavity that recognize environmental odorants and project axons into the olfactory bulb (OB), where they form synapses with several types of neurons...
April 4, 2017: Chemical Senses
https://www.readbyqxmd.com/read/28349579/periodic-olfactory-assessment-in-patients-undergoing-skull-base-surgery-with-preservation-of-the-olfactory-strip
#4
Smita Upadhyay, Lamia Buohliqah, Ricardo L L Dolci, Bradley A Otto, Daniel M Prevedello, Ricardo L Carrau
OBJECTIVES/HYPOTHESIS: Others have reported olfactory disturbances following endoscopic approaches to the skull base. However, there is a lack of consensus on the extent and duration of dysfunction. This study aimed to compare our results with previously published work and to validate the olfactory strip-sparing approach. STUDY DESIGN: Prospective study to assess olfaction in 50 patients scheduled to undergo resection of skull base tumors via extended endoscopic approaches...
March 27, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28346647/validation-of-olfactory-threshold-testing-methods
#5
Alan Hirsch, Alexander Roussos, Sally Freels
In patients with chemosensory complaints, a head-to-head comparison of unilateral olfaction threshold testing with the Phenyl Ethyl Alcohol Smell Threshold Test (PEA) and the OLFACT-RL Odor Threshold Test (OLFACT-RL) was undertaken. The charts of 23 consecutive patients presenting with chemosensory complaints seen at the Smell and Taste Treatment and Research Foundation were reviewed and information extracted per Institutional Review Board guidelines. All patients had undergone olfactory testing with the PEA test and the OLFACT-RL test in accordance with their published administration manuals...
March 2017: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/28344819/olfaction-as-a-soldier-a-review-of-the-physiology-and-its-present-and-future-use-in-the-military
#6
REVIEW
Palaniappan Ganesh Nagappan, Somasundram Subramaniam, De-Yun Wang
Olfaction is one of our 5 main qualitative sensory abilities. In this review, we have examined the physiology of olfaction from the olfactory receptor to the brain. Through analyzing the physiology of olfaction, we have found that the biochemistry of olfactory nerve stimulation is unique from that of other similar pathways. Upon receiving large amounts of input from the olfactory nerve, the olfactory bulb, followed by several layers of centrifugal and centripetal processing in the brain, has to sort the information from the input as well as integrate it with other inputs from the brain to develop a coherent understanding of the input...
2017: Military Medical Research
https://www.readbyqxmd.com/read/28302020/olfactory-loss-management-in-view-of-avicenna-focus-on-neuroprotective-plants
#7
Farnaz Sinaei, Seyed Ahmad Emami, Amirhossein Sahebkar, Behjat Javadi
BACKGROUND: Loss of olfaction can cause noticeable reduction in general quality of life. Only a small portion of patients with olfactory loss respond to current medications. Thus, development of novel therapeutic strategies seems to be necessary. Looking into traditional medical knowledge can be of great value in addressing useful remedies. Traditional Persian Medicine (TPM) has been practiced in Persia for more than 2000 years. Avicenna is the most eminent Persian physician. OBJECTIVE: To survey Avicenna's views on etiology and management of olfactory loss and to search for relevant modern pharmacological data...
March 16, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28289233/volatile-secondary-metabolites-as-aposematic-olfactory-signals-and-defensive-weapons-in-aquatic-environments
#8
Giuseppe Giordano, Marianna Carbone, Maria Letizia Ciavatta, Eleonora Silvano, Margherita Gavagnin, Mary J Garson, Karen L Cheney, I Wayan Mudianta, Giovanni Fulvio Russo, Guido Villani, Laura Magliozzi, Gianluca Polese, Christian Zidorn, Adele Cutignano, Angelo Fontana, Michael T Ghiselin, Ernesto Mollo
Olfaction is considered a distance sense; hence, aquatic olfaction is thought to be mediated only by molecules dissolved in water. Here, we challenge this view by showing that shrimp and fish can recognize the presence of hydrophobic olfactory cues by a "tactile" form of chemoreception. We found that odiferous furanosesquiterpenes protect both the Mediterranean octocoral Maasella edwardsi and its specialist predator, the nudibranch gastropod Tritonia striata, from potential predators. Food treated with the terpenes elicited avoidance responses in the cooccurring shrimp Palaemon elegans Rejection was also induced in the shrimp by the memory recall of postingestive aversive effects (vomiting), evoked by repeatedly touching the food with chemosensory mouthparts...
March 28, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28243501/validation-of-olfactory-deficit-as-a-biomarker-of-alzheimer-disease
#9
Matthew R Woodward, Chaitanya V Amrutkar, Harshit C Shah, Ralph H B Benedict, Sanjanaa Rajakrishnan, Rachelle S Doody, Li Yan, Kinga Szigeti
BACKGROUND: We evaluated smell identification as a biomarker for Alzheimer disease (AD) by assessing its utility in differentiating normal aging from an amnestic disorder and determining its predictive value for conversion from amnestic mild cognitive impairment (aMCI) to AD. METHODS: Cross-sectional study (AD = 262, aMCI = 110, controls = 194) measuring smell identification (University of Pennsylvania Smell Identification Test [UPSIT]) and cognitive status was performed, as well as longitudinal analysis of aMCI participants (n = 96) with at least 1 year follow-up (mean 477...
February 2017: Neurology. Clinical Practice
https://www.readbyqxmd.com/read/28242521/a-systematic-review-of-smell-alterations-after-radiotherapy-for-head-and-neck-cancer
#10
REVIEW
M Álvarez-Camacho, S Gonella, S Campbell, R A Scrimger, W V Wismer
PURPOSE: To review the current knowledge on radiotherapy associated olfactory dysfunction among head and neck cancer (HNC) patients. METHODS: A systematic review of RT-related olfactory dysfunction in HNC was performed. Searches were conducted in several databases (Medline, EMBASE, CINAHL, CAB Abstracts, SCOPUS, Proquest Dissertations and Theses, PROSPERO, ALLEBM Reviews - Cochrane DSR, ACP Journal Club, DARE, CCTR, CMR, HTA, and NHSEED). Publications investigating olfactory dysfunction as an explicit side effect of Radiotherapy (RT, or RT-chemo or RT-monoclonal antibodies) were eligible, no limits were applied...
March 2017: Cancer Treatment Reviews
https://www.readbyqxmd.com/read/28242255/olfactory-dysfunction-and-dementia-in-newly-diagnosed-patients-with-parkinson-s-disease
#11
Magdalena Eriksson Domellöf, Karl-Fredrik Lundin, Mona Edström, Lars Forsgren
INTRODUCTION: Studies report that up to 90% of patients with idiopathic Parkinson's disease (PD) have olfactory dysfunction (hyposmia). Hyposmia has also been connected to cognitive impairment and dementia in PD, but no studies of newly diagnosed patients followed longer than three years exists. The present study investigates the prevalence of olfactory dysfunction at PD diagnosis, how it evolves over time and whether hyposmia increases the risk of dementia in Parkinson's disease. METHODS: Olfactory function was assessed with Brief Smell Identification Test (B-SIT) in 125 newly diagnosed patients with PD...
February 21, 2017: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/28219971/predicting-human-olfactory-perception-from-chemical-features-of-odor-molecules
#12
Andreas Keller, Richard C Gerkin, Yuanfang Guan, Amit Dhurandhar, Gabor Turu, Bence Szalai, Joel D Mainland, Yusuke Ihara, Chung Wen Yu, Russ Wolfinger, Celine Vens, Leander Schietgat, Kurt De Grave, Raquel Norel, Gustavo Stolovitzky, Guillermo A Cecchi, Leslie B Vosshall, Pablo Meyer
It is still not possible to predict whether a given molecule will have a perceived odor or what olfactory percept it will produce. We therefore organized the crowd-sourced DREAM Olfaction Prediction Challenge. Using a large olfactory psychophysical data set, teams developed machine-learning algorithms to predict sensory attributes of molecules based on their chemoinformatic features. The resulting models accurately predicted odor intensity and pleasantness and also successfully predicted 8 among 19 rated semantic descriptors ("garlic," "fish," "sweet," "fruit," "burnt," "spices," "flower," and "sour")...
February 24, 2017: Science
https://www.readbyqxmd.com/read/28158212/significant-improvement-of-olfactory-performance-in-sleep-apnea-patients-after-three-months-of-nasal-cpap-therapy-observational-study-and-randomized-trial
#13
Bettina Boerner, Gabrielo M Tini, Patrick Fachinger, Sereina M Graber, Sarosh Irani
OBJECTIVES: The olfactory function highly impacts quality of life (QoL). Continuous positive airway pressure is an effective treatment for obstructive sleep apnea (OSA) and is often applied by nasal masks (nCPAP). The influence of nCPAP on the olfactory performance of OSA patients is unknown. The aim of this study was to assess the sense of smell before initiation of nCPAP and after three months treatment, in moderate and severe OSA patients. METHODS: The sense of smell was assessed in 35 patients suffering from daytime sleepiness and moderate to severe OSA (apnea/hypopnea index ≥ 15/h), with the aid of a validated test battery (Sniffin' Sticks) before initiation of nCPAP therapy and after three months of treatment...
2017: PloS One
https://www.readbyqxmd.com/read/28134639/complications-of-nasal-bone-fractures
#14
Kun Hwang, Seung Han Yeom, Suk Hyun Hwang
The aim of this study was to perform a systematic review of the treatment of nasal bone fractures. The search terms ("nasal bone fracture" AND complication) and ("nasal bone fracture" AND [anosmia OR olfaction OR olfactory nerve OR smell]) and (anosmia AND ["nasal preparation" OR "nasal antiseptics"]) were used to search PubMed and SCOPUS. Of the 500 titles, 40 full papers were reviewed. One paper was excluded, and 3 mined papers were added. Ultimately, 12 papers were analyzed. The overall deformity rate was 10...
January 27, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28122475/the-relationship-between-olfactory-dysfunction-and-executive-function-in-children-with-traumatic-brain-injury
#15
Kathleen Bakker, Cathy Catroppa, Vicki Anderson
INTRODUCTION: Olfactory dysfunction (OD) has been suggested as a possible marker of executive function (EF) deficits after traumatic brain injury (TBI) in adults. Little is known about the relationship between EF and OD in pediatric TBI (pTBI). This study aimed to investigate EF, explore the relationship between OD and EF, and determine the utility of olfactory performance as a marker of later EF in pTBI. It was hypothesized that (i) children with TBI would perform more poorly on EF measures relative to normative expectation; (ii) children with OD would perform more poorly on tests of EF than those with normal olfaction after TBI; and (iii) acute olfactory function would predict later EF for children with TBI...
January 25, 2017: Journal of Clinical and Experimental Neuropsychology
https://www.readbyqxmd.com/read/28112677/seeing-how-we-smell
#16
Helene Benveniste, Yuri Lazebnik, Nora D Volkow
PET allows noninvasive imaging of a variety of events in the body, including the activity of neuronal circuits in the brain that are involved in cognition and behaviors, by using radiotracers that detect relevant biological reactions. A major impediment to expanding PET applications to study the brain has been the lack of radiotracers that can identify and measure specific types of neurons or glial cells. In this issue of the JCI, Van de Bittner and colleagues describe a promising step toward solving this problem by identifying and describing a radiotracer, [11C]GV1-57, that appears to specifically label olfactory sensory neurons (OSNs), which are essential for olfaction (Figure 1)...
February 1, 2017: Journal of Clinical Investigation
https://www.readbyqxmd.com/read/28107119/olfaction-new-understandings-diagnostic-applications
#17
Gabrielle F Ruggiero, Jeannette Y Wick
Estimates indicate that 14 million Americans have olfactory dysfunction. As with other senses, such as sight and hearing, olfaction frequently declines with age. Impaired olfaction can be a warning sign of Parkinson's disease, sometimes occurring before motor symptoms develop. It's also an initial symptom of Alzheimer's dementia (AD); the amyloid plaques and tangles characterizing AD invade the olfactory bulb and hippocampus early in its course, hampering odor identification. Olfactory dysfunction is associated with some serious problems, including inability to smell warning odors (fire, gas) and impaired ability to taste food...
November 1, 2016: Consultant Pharmacist: the Journal of the American Society of Consultant Pharmacists
https://www.readbyqxmd.com/read/28103755/what-makes-a-better-smeller
#18
Asifa Majid, Laura Speed, Ilja Croijmans, Artin Arshamian
Olfaction is often viewed as difficult, yet the empirical evidence suggests a different picture. A closer look shows people around the world differ in their ability to detect, discriminate, and name odors. This gives rise to the question of what influences our ability to smell. Instead of focusing on olfactory deficiencies, this review presents a positive perspective by focusing on factors that make someone a better smeller. We consider three driving forces in improving olfactory ability: one's biological makeup, one's experience, and the environment...
January 1, 2017: Perception
https://www.readbyqxmd.com/read/28039314/olfaction-and-risk-of-dementia-in-a-biracial-cohort-of-older-adults
#19
Kristine Yaffe, Daniel Freimer, Honglei Chen, Keiko Asao, Andrea Rosso, Susan Rubin, Greg Tranah, Steve Cummings, Eleanor Simonsick
OBJECTIVE: Prior studies indicate that olfactory function may be an early marker for cognitive impairment, but the body of evidence has been largely restricted to white populations. METHODS: We studied 2,428 community-dwelling black and white older adults (baseline age 70-79 years) without dementia enrolled in the Health, Aging, and Body Composition (Health ABC) study. Olfaction was measured as odor identification (OI) with the 12-item Cross Cultural Smell Identification Test in year 3...
January 31, 2017: Neurology
https://www.readbyqxmd.com/read/28038387/on-the-nose-olfactory-disturbances-in-patients-with-transient-epileptic-amnesia
#20
Sharon A Savage, Christopher R Butler, Fraser Milton, Yang Han, Adam Z Zeman
OBJECTIVE: While olfactory hallucinations are relatively rare in epilepsy, a high prevalence (up to 42%) has been reported in one form - Transient Epileptic Amnesia (TEA). TEA is characterized by recurring amnestic seizures and is commonly associated with persistent interictal memory deficits. Despite reports of changes in smell, olfactory ability has not been objectively assessed in this group. The aim of this study was to measure olfactory ability in patients with TEA and explore whether olfactory symptoms relate to other clinical variables...
January 2017: Epilepsy & Behavior: E&B
keyword
keyword
13456
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"