keyword
MENU ▼
Read by QxMD icon Read
search

Smell

keyword
https://www.readbyqxmd.com/read/28213192/trans-frontal-sinus-subcranial-approach-to-olfactory-groove-meningiomas-surgical-results-clinical-and-functional-outcome-in-a-consecutive-series-of-21-patients
#1
Lina Raffaella Barzaghi, Alfio Spina, Filippo Gagliardi, Nicola Boari, Pietro Mortini
BACKGROUND: The trans-frontal-sinus-subcranial approach (TFSSA) allows for direct exposure and removal of olfactory groove meningiomas (OGMs), without any brain retraction. Compared to other skull base approaches (like fronto-orbito-basal, transbasal, subcranial, fronto-orbito-zygomatic and one-and-half approach), it could offer the same advantages but it is less invasive. OBJECT: We report the results in a series of 21 consecutive patients harboring OGMs and operated through TFSSA, in order to propose a viable alternative approach...
February 14, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28212942/activation-of-type-4-dopaminergic-receptors-in-the-prelimbic-area-of-medial-prefrontal-cortex-is-necessary-for-the-expression-of-innate-fear-behavior
#2
Macarena D Vergara, Victor N Keller, José A Fuentealba, Katia Gysling
The prelimbic area (PL) of the medial Prefrontal cortex (mPFC) is involved in the acquisition and expression of conditioned and innate fear. Both types of fear share several neuronal pathways. It has been documented that dopamine (DA) plays an important role in the regulation of aversive memories in the mPFC. The exposure to an aversive stimulus, such as the smell of a predator odor or the exposure to footshock stress is accompanied by an increase in mPFC DA release. Evidence suggests that the type 4 dopaminergic receptor (D4R) is the molecular target through which DA modulates fear expression...
February 14, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28210930/emotion-specific-nocebo-effects-an-fmri-study
#3
Anne Schienle, Carina Höfler, Sonja Übel, Albert Wabnegger
The neurobiological mechanisms of nocebos are still poorly understood. Thirty-eight women participated in a 'smell study' using functional magnetic resonance imaging. They were presented with an odorless stimulus (distilled water) together with the verbal suggestion that this fluid has an aversive odor which enhances disgust feelings. The nocebo was presented while the participants viewed disgusting, fear-inducing, and neutral images. Participants' affective and neuronal responses during nocebo administration were compared with those in a control condition without nocebo...
February 16, 2017: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/28208947/delayed-uterine-necrosis-rare-cause-of-nonhealing-wound
#4
Aruna Nigam, Neha Gupta, Arifa A Elahi, Zeeba S Jairajpuri, Swaraj Batra
Uterine necrosis is a very rare condition and most of the reported cases occurred after pelvic arterial embolization for post-partum haemorrhage, embolization of fibroid uterus or application of B-Lynch sutures. A case of delayed myometrial necrosis is reported in post-cesarean patient where no embolization or uterine compression sutures have been applied. Patient presented with foul smelling discharge from the gaped abdominal wound following caesarean section. Abdomen was closed after exploration and lavage...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28207861/in-vitro-anti-herpes-simplex-virus-2-activity-of-salvia-desoleana-atzei-v-picci-essential-oil
#5
Valeria Cagno, Barbara Sgorbini, Cinzia Sanna, Cecilia Cagliero, Mauro Ballero, Andrea Civra, Manuela Donalisio, Carlo Bicchi, David Lembo, Patrizia Rubiolo
Salvia desoleana Atzei & V. Picci is an indigenous species in Sardinia island used in folk medicine to treat menstrual, digestive and central nervous system diseases. Nowadays, it is widely cultivated for the pleasant smell of its essential oil (EO), whose antimicrobial and antifungal activities have already been screened. This study evaluated the in vitro anti-Herpes Simplex Virus-2 (HSV-2) activity of S. desoleana EO, fractions and main components: linalyl acetate, alpha terpinyl acetate, and germacrene D...
2017: PloS One
https://www.readbyqxmd.com/read/28203422/colobronchial-fistula-the-pathogenesis-clinical-presentations-diagnosis-and-treatment
#6
Jinbo Zhao, Nan Ma, Zhengwei Zhao, Jie Lei, Qiang Lu, Feng Tian, Yongan Zhou, Yong Han, Xiaofei Li
BACKGROUND: Colobronchial fistula (CBF) is rare and easy to be delayed in clinic. There is no systemic study about this disease. The pathogenesis, clinical presentations, diagnosis and treatment of CBF were analyzed in this study. METHODS: The clinical data from 37 cases of CBF, which included one case in our institute and the other 36 cases in literature from January 1960 to August 2016, were reviewed and analyzed. The etiology, clinical presentations, diagnostic and therapeutic methods, and outcomes were summarized...
January 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28199564/do-masculine-men-smell-better-an-association-between-skin-color-masculinity-and-female-preferences-for-body-odor
#7
Mariana L Carrito, Isabel M Santos, Laura Alho, Jacqueline Ferreira, Sandra C Soares, Pedro Bem-Haja, Carlos F Silva, David I Perrett
No abstract text is available yet for this article.
February 11, 2017: Chemical Senses
https://www.readbyqxmd.com/read/28199298/synthetic-biology-synthetic-gene-networks-that-smell
#8
Fahim Farzadfard, Timothy K Lu
No abstract text is available yet for this article.
February 15, 2017: Nature Chemical Biology
https://www.readbyqxmd.com/read/28196478/genetic-analysis-of-impaired-trimethylamine-metabolism-using-whole-exome-sequencing
#9
Yiran Guo, Liang-Dar Hwang, Jiankang Li, Jason Eades, Chung Wen Yu, Corrine Mansfield, Alexis Burdick-Will, Xiao Chang, Yulan Chen, Fujiko F Duke, Jianguo Zhang, Steven Fakharzadeh, Paul Fennessey, Brendan J Keating, Hui Jiang, Hakon Hakonarson, Danielle R Reed, George Preti
BACKGROUND: Trimethylaminuria (TMAU) is a genetic disorder whereby people cannot convert trimethylamine (TMA) to its oxidized form (TMAO), a process that requires the liver enzyme FMO3. Loss-of-function variants in the FMO3 gene are a known cause of TMAU. In addition to the inability to metabolize TMA precursors like choline, patients often emit a characteristic odor because while TMAO is odorless, TMA has a fishy smell. The Monell Chemical Senses Center is a research institute with a program to evaluate people with odor complaints for TMAU...
February 15, 2017: BMC Medical Genetics
https://www.readbyqxmd.com/read/28195960/a-prospective-analysis-of-olfactory-impairment-recovery-after-severe-traumatic-brain-injury
#10
Melanie Drummond, Jacinta Douglas, John Olver
OBJECTIVE: To investigate the natural progression of olfactory impairment (OI) in individuals with traumatic brain injury (TBI) at 6 months postinjury. PARTICIPANTS: Forty-seven adults (mean age = 43.1 years, SD = 18.2), with predominantly severe TBI (mean posttraumatic amnesia [PTA] duration = 25.5 days, SD = 22.8). DESIGN: Consecutive admission longitudinal study. MAIN MEASURES: Participants were evaluated using the University of Pennsylvania Smell Identification Test (UPSIT) at resolution of PTA and at 6 months post-initial injury...
February 10, 2017: Journal of Head Trauma Rehabilitation
https://www.readbyqxmd.com/read/28195066/successful-therapy-of-clostridium-difficile-infection-with-fecal-microbiota-transplantation
#11
P C Konturek, J Koziel, W Dieterich, D Haziri, S Wirtz, I Glowczyk, K Konturek, M F Neurath, Y Zopf
Clostridium difficile infection (CDI) is the most common cause of infectious diarrhea and represents an important burden for healthcare worldwide. Symptoms of severe CDI include watery, foul-smelling diarrhea, peripheral leucocytosis, increased C-reactive protein (CRP), acute renal failure, hypotension and pseudomembranous colitis. Recent studies indicate that the main cause of CDI is dysbiosis, an imbalance in the normal gut microbiota. The restoration of a healthy gut microbiota composition via fecal microbiota transplantation (FMT) recently became more popular...
December 2016: Journal of Physiology and Pharmacology: An Official Journal of the Polish Physiological Society
https://www.readbyqxmd.com/read/28191520/a-rose-by-any-name-surely-does-smell-just-as-sweetly-the-controversy-over-revised-nomenclature-for-encapsulated-follicular-variant-papillary-carcinoma
#12
Leonard Wartofsky
No abstract text is available yet for this article.
June 1, 2016: Journal of Translational Internal Medicine
https://www.readbyqxmd.com/read/28183033/diabetic-nephropathy-a-potential-savior-with-rotten-egg-smell
#13
REVIEW
George J Dugbartey
Diabetic nephropathy (DN) is currently the leading cause of end-stage renal disease. Despite optimal management, DN is still a major contributor to morbidity and mortality of diabetic patients worldwide. The major pathological alterations in DN include excessive accumulation and deposition of extracellular matrix, leading to expansion of mesangial matrix, thickening of glomerular basement membrane and tubulointerstitial fibrosis. At the molecular level, accumulating evidence suggests that hyperglycemia or high glucose mediates renal injury in DN via multiple molecular mechanisms such as induction of oxidative stress, upregulation of renal transforming growth factor beta-1 expression, production of proinflammatory cytokines, activation of fibroblasts and renin angiotensin system, and depletion of adenosine triphosphate...
November 11, 2016: Pharmacological Reports: PR
https://www.readbyqxmd.com/read/28176228/primary-uterine-diffuse-large-b-cell-lymphoma-dlbcl-in-a-patient-with-prolonged-insertion-of-intrauterine-device-iud
#14
Takuya Shimizu, Kazuo Hatanaka, Hitomi Kaneko, Toshihide Shimada, Kazunori Imada
A 49-year-old female from China was referred to our hospital after endocervical polypectomy. Twenty years before admission, after the birth of her first child, an intrauterine device (IUD) had been inserted due to the one-child policy in China. She had noticed abnormal vaginal bleeding with a foul smell 3 years before admission. Then the IUD was removed and a polyp was found at the IUD contact site. Two months before admission, endocervical polypectomy was performed. Lymphoma was suspected by histological examination and she was referred to our hospital...
February 7, 2017: International Journal of Hematology
https://www.readbyqxmd.com/read/28174164/improving-malodour-management-in-advanced-cancer-a-10-year-retrospective-study-of-topical-oral-and-maintenance-metronidazole
#15
Reena George, Thotampuri Shanthi Prasoona, Ramu Kandasamy, Renitha Cherian, Thangarathi Celine, Jenifer Jeba, Shakila Murali, David Mathew
OBJECTIVES: To explore the relative effectiveness of topical or oral metronidazole used for malodour in necrotic cancers and to propose a protocol for metronidazole usage in managing malodour. METHODS: A retrospective case note review of the management of malodour over 10 years comparing outcomes with topical, intermittent and maintenance oral metronidazole. RESULTS: Among 179 patients treated for malodour, the commonest primaries were cervical (45%), and head and neck cancers (40%)...
February 6, 2017: BMJ Supportive & Palliative Care
https://www.readbyqxmd.com/read/28167233/taste-and-smell-gpcrs-in-the-lung-evidence-for-a-previously-unrecognized-widespread-chemosensory-system
#16
REVIEW
Steven S An, Stephen B Liggett
Taste and smell receptor expression has been traditionally limited to the tongue and nose. We have identified bitter taste receptors (TAS2Rs) and olfactory receptors (ORs) on human airway smooth muscle (HASM) cells. TAS2Rs signal to PLCβ evoking an increase in [Ca(2+)]i causing membrane hyperpolarization and marked HASM relaxation ascertained by single cell, ex vivo, and in vivo methods. The presence of TAS2Rs in the lung was unexpected, as was the bronchodilatory function which has been shown to be due to signaling within specific microdomains of the cell...
February 4, 2017: Cellular Signalling
https://www.readbyqxmd.com/read/28160522/isoprene-research-60%C3%A2-years-later-the-biology-is-still-enigmatic
#17
REVIEW
Thomas D Sharkey, Russell K Monson
Isoprene emission is a major component of biosphere-atmosphere interactions. It is the single largest source of non-methane hydrocarbon in the atmosphere. The first report of isoprene emission from plants was published in 1957 by Professor Guivi Sanadze. While humans have smelled the monoterpene hydrocarbons made by coniferous trees since their earliest migrations, only in 1957 did the world became aware that other trees make a type of hydrocarbon in even greater amounts, but one to which the human nose is much less sensitive...
February 4, 2017: Plant, Cell & Environment
https://www.readbyqxmd.com/read/28159906/identity-specific-reward-representations-in-orbitofrontal-cortex-are-modulated-by-selective-devaluation
#18
James D Howard, Thorsten Kahnt
: Goal-directed behavior is sensitive to the current value of expected outcomes. This requires independent representations of specific rewards, which have been linked to orbitofrontal cortex (OFC) function. However, the mechanisms by which the human brain updates specific goals on the fly, and translates those updates into choices, have remained unknown. Here we implemented selective devaluation of appetizing food odors in combination with pattern-based neuroimaging and a decision-making task...
February 3, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28158237/an-increase-in-visceral-fat-is-associated-with-a-decrease-in-the-taste-and-olfactory-capacity
#19
Jose Carlos Fernandez-Garcia, Juan Alcaide, Concepcion Santiago-Fernandez, M M Roca-Rodriguez, Zaida Aguera, Rosa Baños, Cristina Botella, Rafael de la Torre, Jose M Fernandez-Real, Gema Fruhbeck, Javier Gomez-Ambrosi, Susana Jimenez-Murcia, Jose M Menchon, Felipe F Casanueva, Fernando Fernandez-Aranda, Francisco J Tinahones, Lourdes Garrido-Sanchez
INTRODUCTION: Sensory factors may play an important role in the determination of appetite and food choices. Also, some adipokines may alter or predict the perception and pleasantness of specific odors. We aimed to analyze differences in smell-taste capacity between females with different weights and relate them with fat and fat-free mass, visceral fat, and several adipokines. MATERIALS AND METHODS: 179 females with different weights (from low weight to morbid obesity) were studied...
2017: PloS One
https://www.readbyqxmd.com/read/28158212/significant-improvement-of-olfactory-performance-in-sleep-apnea-patients-after-three-months-of-nasal-cpap-therapy-observational-study-and-randomized-trial
#20
Bettina Boerner, Gabrielo M Tini, Patrick Fachinger, Sereina M Graber, Sarosh Irani
OBJECTIVES: The olfactory function highly impacts quality of life (QoL). Continuous positive airway pressure is an effective treatment for obstructive sleep apnea (OSA) and is often applied by nasal masks (nCPAP). The influence of nCPAP on the olfactory performance of OSA patients is unknown. The aim of this study was to assess the sense of smell before initiation of nCPAP and after three months treatment, in moderate and severe OSA patients. METHODS: The sense of smell was assessed in 35 patients suffering from daytime sleepiness and moderate to severe OSA (apnea/hypopnea index ≥ 15/h), with the aid of a validated test battery (Sniffin' Sticks) before initiation of nCPAP therapy and after three months of treatment...
2017: PloS One
keyword
keyword
13454
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"