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https://www.readbyqxmd.com/read/28938325/the-effect-of-dexpanthenol-vitamin-a-nazalnem-on-silastic-splints-after-nasal-septal-surgery
#1
Güven Yildirim, Tolgar Lütfi Kumral, Cem Altindağ, Erdi Özdemir, Yavuz Uyar
OBJECTIVE: To investigate the effect of dexpanthenol-vitamin A (Nazalnem) ointment applied to the surface of silastic splints with an airway immediately after nasal septal surgery on postoperative complaints and nasal mucosa function. MATERIALS AND METHODS: The study enrolled 60 patients undergoing nasal septoplasty surgery. Group 1 (n = 30) received silastic splints with ointment containing dexpanthenol-vitamin A (Nazalnem), and Group 2 (n = 30), the control group, received silastic splints with vaseline...
September 21, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28934654/a-case-study-of-air-quality-pesticides-and-odorous-phytochemicals-on-kauai-hawaii-usa
#2
Jun Wang, Robert Boesch, Qing X Li
This study was conducted after a series of incidences occurred at Waimea Canyon Middle School on Kauai, Hawaii. Some students and staff members exhibited symptoms such as throat irritation, tearing, and dizziness. These symptoms could be associated with natural causes or human activities, which include exposures to pesticides and odorous phytochemicals. At the time of the occurrences, Cleome gynandra (known locally as stinkweed) was growing in the fields near the school and might be a potential cause of the reported symptoms...
September 14, 2017: Chemosphere
https://www.readbyqxmd.com/read/28933478/natural-product-modulators-of-human-sensations-and-mood-molecular-mechanisms-and-therapeutic-potential
#3
REVIEW
Tomáš Pluskal, Jing-Ke Weng
Humans perceive physical information about the surrounding environment through their senses. This physical information is registered by a collection of highly evolved and finely tuned molecular sensory receptors. A multitude of bioactive, structurally diverse ligands have evolved in nature that bind these molecular receptors. The complex, dynamic interactions between the ligands and the receptors lead to changes in our sensory perception or mood. Here, we review our current knowledge of natural products and their derived analogues that interact specifically with human G protein-coupled receptors, ion channels, and nuclear hormone receptors to modulate the sensations of taste, smell, temperature, pain, and itch, as well as mood and its associated behaviour...
September 21, 2017: Chemical Society Reviews
https://www.readbyqxmd.com/read/28932845/sulphur-fertilization-influences-the-sulphur-species-composition-in-allium-sativum-sulphomics-using-hplc-icpms-ms-esi-ms-ms
#4
Andrea Raab, Marilena Ronzan, Joerg Feldmann
Garlic (A. sativum) contains a large number of small sulphur (S)-containing metabolites, which are important for its taste and smell and vary with A. sativum variety and growth conditions. This study was designed to investigate the influence of different sulphur-fertilization regimes on low molecular weight S-species by attempting the first sulphur mass balance in A. sativum roots and bulbs using HPLC-ICPMS/MS-ESI-MS/MS. Species unspecific quantification of acid soluble S-containing metabolites was achieved using HPLC-ICP-MS/MS...
September 21, 2017: Metallomics: Integrated Biometal Science
https://www.readbyqxmd.com/read/28932343/babies-smell-wonderful-to-their-parents-teenagers-do-not-an-exploratory-questionnaire-study-on-children-s-age-and-personal-odor-ratings-in-a-polish-sample
#5
Ilona Croy, Tomasz Frackowiak, Thomas Hummel, Agnieszka Sorokowska
INTRODUCTION: Infant body odor is subjectively pleasant to parents and activates reward areas in the brain. Hence, body odor perception might contribute to parental bonding. However, it is unknown whether the perceived pleasantness of children's body odor varies over the course of a child's development. METHODS: Two hundred and thirty-five parents (M = 36.9 years, SD = 7.3) were asked to assess the personal odor pleasantness of their children (N = 367; M = 9...
2017: Chemosensory Perception
https://www.readbyqxmd.com/read/28930230/angelica-sinensis-oliv-diels-influence-of-value-chain-on-quality-criteria-and-marker-compounds-ferulic-acid-and-z-ligustilide
#6
Nino Giacomelli, Yang Yongping, Franz K Huber, Anita Ankli, Caroline S Weckerle
Background:Dang gui (Apiaceae; Angelica sinensis radix) is among the most often used Chinese medicinal plants. However, hardly anything is known about its value chain and its influence on the main marker compounds of the drug. The aim of this study is to investigate the value chain of dang gui in Gansu and Yunnan, and the analysis of the marker compounds ferulic acid and Z-ligustilide concentration in relation to quality criteria such as the production area and size of the roots. Methods: During six months of field research in China, semi-structured interviews with various stakeholders of the value chain were undertaken and plant material was collected...
March 14, 2017: Medicines (Basel, Switzerland)
https://www.readbyqxmd.com/read/28928777/determination-of-salivary-urea-and-uric-acid-of-patients-with-halitosis
#7
Faezeh Khozeimeh, Nakisa Torabinia, Shirin Shahnaseri, Hooman Shafaee, Seyed Amir Mousavi
BACKGROUND: Halitosis is the presence of unpleasant or foul smelling breath. The origin of halitosis may be related to both systemic and oral conditions, but a large percentage of cases, about 90%, is generally related to an oral cause. The aim of this study was to compare the concentration of urea and uric acid in patients with halitosis and people without halitosis. MATERIALS AND METHODS: In this case-control study, concentration of urea and uric acid was compared between two groups: (1) persons suffering halitosis (2) control group without halitosis...
July 2017: Dental Research Journal
https://www.readbyqxmd.com/read/28927877/gonadotropin-releasing-hormone-by-any-other-name-would-smell-as-sweet
#8
Pei-San Tsai
The goal of this article is to discuss the nomenclature of members of the gonadotropin-releasing hormone (GnRH) superfamily. This superfamily currently consists of 5 families: (1) vertebrate GnRH, (2) adipokinetic hormone, (3) corazonin, (4) adipokinetic hormone/corazonin-related peptide and (5) invertebrate GnRH (or GnRH/corazonin). The naming of some of these peptides, especially members of the invertebrate GnRH family, may not have reflected their true evolutionary origin, leading to some confusion and controversy...
September 18, 2017: General and Comparative Endocrinology
https://www.readbyqxmd.com/read/28927319/angular-versus-curved-shapes-correspondences-and-emotional-processing
#9
Olesya Blazhenkova, Melisa Maya Kumar
The present work aimed to systematically examine sensory and higher level correspondences to angular and curved shapes. Participants matched angular and curved abstract shapes to sensory experiences in five different modalities as well as to emotion, gender, and name attributes presented as written labels (Study 1) and real experiences (Study 2). The results demonstrated nonarbitrary mapping of angular and curved shapes to attributes from all basic sensory modalities (vision, audition, gustation, olfaction, and tactation) and higher level attributes (emotion, gender, and name)...
January 1, 2017: Perception
https://www.readbyqxmd.com/read/28926863/evaluation-of-cannabinoid-and-terpenoid-content-cannabis-flower-compared-to-supercritical-co2-concentrate
#10
Michelle Sexton, Kyle Shelton, Pam Haley, Mike West
A recent cannabis use survey revealed that 60% of cannabis users rely on smelling the flower to select their cannabis. Olfactory indicators in plants include volatile compounds, principally represented by the terpenoid fraction. Currently, medicinal- and adult-use cannabis is marketed in the United States with relatively little differentiation between products other than by a common name, association with a species type, and Δ-9 tetrahydrocannabinol/cannabidiol potency. Because of this practice, how terpenoid compositions may change during an extraction process is widely overlooked...
September 19, 2017: Planta Medica
https://www.readbyqxmd.com/read/28923606/actinomycetes-benefaction-role-in-soil-and-plant-health
#11
REVIEW
Asma Absar Bhatti, Shamsul Haq, Rouf Ahmad Bhat
Actinomycetes are aerobic, spore forming gram-positive bacteria, belonging to the order actinomycetales characterized with substrate and aerial mycelium growth. They are the most abundant organisms that form thread-like filaments in the soil and are responsible for characteristically "earthy" smell of freshly turned healthy soil. They play major roles in the cycling of organic matter; inhibit the growth of several plant pathogens in the rhizosphere and decompose complex mixtures of polymer in dead plant, animal and fungal material results in production of many extracellular enzymes which are conductive to crop production...
September 18, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28923431/both-anxiety-and-joint-laxity-determine-the-olfactory-features-in-panic-disorder
#12
Emma Burón, Antonio Bulbena, Andrea Bulbena-Cabré, Sílvia Rosado, Guillem Pailhez
Previous research showed a high sensitivity in sensorial modalities in panic disorder (PD). This disorder has been consistently associated to the joint hypermobility syndrome (JHS). In non-clinical samples, this collagen alteration has been also related to an enhanced sensitivity in some sensorial modalities. The main aim of this study is to explore the olfactory functioning in PD in relation to JHS. Sixty patients with PD and sixty healthy controls performed the Sniffin' Sticks Test (SST) (threshold subtest), and completed the Affective Impact of Odors scale (AIO), the Relational Scale of Olfaction (EROL), and the Odor Awareness Scale (OAS)...
September 11, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28918258/olfactory-function-in-an-excitotoxic-model-for-secondary-neuronal-degeneration-role-of-dopaminergic-interneurons
#13
Concepció Marin, Sara Laxe, Cristobal Langdon, Joan Berenguer, Eduardo Lehrer, Franklin Mariño-Sánchez, Isam Alobid, Montserrat Bernabeu, Joaquim Mullol
Secondary neuronal degeneration (SND) occurring in Traumatic brain injury (TBI) consists in downstream destructive events affecting cells that were not or only marginally affected by the initial wound, further increasing the effects of the primary injury. Glutamate excitotoxicity is hypothesized to play an important role in SND. TBI is a common cause of olfactory dysfunction that may be spontaneous and partially recovered. The role of the glutamate excitotoxicity in the TBI-induced olfactory dysfunction is still unknown...
September 13, 2017: Neuroscience
https://www.readbyqxmd.com/read/28917744/differentiation-of-cumin-seeds-using-a-metal-oxide-based-gas-sensor-array-in-tandem-with-chemometric-tools
#14
Mahdi Ghasemi-Varnamkhasti, Zahra Safari Amiri, Mojtaba Tohidi, Majid Dowlati, Seyed Saeid Mohtasebi, Adenilton C Silva, David D S Fernandes, Mário C U Araujo
Cumin is a plant of the Apiaceae family (umbelliferae) which has been used since ancient times as a medicinal plant and as a spice. The difference in the percentage of aromatic compounds in cumin obtained from different locations has led to differentiation of some species of cumin from other species. The quality and price of cumin vary according to the specie and may be an incentive for the adulteration of high value samples with low quality cultivars. An electronic nose simulates the human olfactory sense by using an array of sensors to distinguish complex smells...
January 1, 2018: Talanta
https://www.readbyqxmd.com/read/28912301/early-onset-drug-induced-parkinsonism-after-exposure-to-offenders-implies-nigrostriatal-dopaminergic-dysfunction
#15
Seok Jong Chung, Han Soo Yoo, Hyojeong Moon, Jungsu S Oh, Jae Seung Kim, Yong Hee Park, Jin Yong Hong, Byoung Seok Ye, Young H Sohn, Phil Hyu Lee
OBJECTIVES: The onset of parkinsonism in patients with drug-induced parkinsonism (DIP) exhibits extensive individual variability following exposure to offending drugs. We investigated whether the individual variations in the onset time of parkinsonism reflected the underlying subtle dopaminergic dysfunction in DIP. METHODS: We enrolled 71 patients with DIP who had visually normal striatal dopamine transporter (DAT) availability in (18)F-FP-CIT positron emission tomography scans...
September 14, 2017: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/28910612/smells-familiar-pheromone-induced-neurotransmitter-switching-mediates-social-discrimination
#16
Michael Gliksberg, Gil Levkowitz
Social discrimination is regulated by a variety of sensory inputs. In this issue of Neuron, Dulcis et al. (2017) show that chemosensory-mediated kin preference in Xenopus is determined by changes in neurotransmitter composition, which are regulated by specific microRNAs.
September 13, 2017: Neuron
https://www.readbyqxmd.com/read/28910182/consumers-perceptions-of-edible-marijuana-products-for-recreational-use-likes-dislikes-and-reasons-for-use
#17
Kristen C Giombi, Katherine M Kosa, Carrie Rains, Sheryl C Cates
BACKGROUND: Edible marijuana products have become extremely popular in states that have legalized marijuana for recreational use. OBJECTIVES: The goal of this research was to provide a better understanding of consumer perceptions of edible marijuana products, including why they prefer edibles relative to other forms of marijuana (e.g., smoking) and their concerns regarding the consumption of edibles. METHODS: We conducted eight focus groups (four groups in Denver, Colorado, and four groups in Seattle, Washington) in February 2016 with 62 adult consumers of edibles...
September 14, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28901845/a-review-of-patents-on-therapeutic-potential-and-delivery-of-hydrogen-sulfide
#18
Richa Verma, Yumna Akhtar, Somnath Singh
Hydrogen sulfide (H2S) is a colorless gas with a characteristic smell of rotten eggs. Once only thought of as a toxic gas, evidence now shows that H2S plays major roles in pathological and physiological activities. These roles are being utilized to treat diseases and disorders ranging from hypertension, inflammation, edema, cardiovascular issues, chronic pain, cancer, and many more. Challenges facing the use of H2S currently involve achieving the optimum therapeutic concentrations, synthesizing chemically and physiologically stable donors, and developing clinically appropriate delivery systems...
September 11, 2017: Recent Patents on Drug Delivery & Formulation
https://www.readbyqxmd.com/read/28901711/learning-to-name-smells-increases-activity-in-heteromodal-semantic-areas
#19
Arnaud Fournel, Caroline Sezille, Carmen C Licon, Charlotte Sinding, Johannes Gerber, Camille Ferdenzi, Thomas Hummel, Moustafa Bensafi
Semantic description of odors is a cognitively demanding task. Learning to name smells is, however, possible with training. This study set out to examine how improvement in olfactory semantic knowledge following training reorganizes the neural representation of smells. First, 19 nonexpert volunteers were trained for 3 days; they were exposed (i) to odorants presented without verbal labels (perceptual learning) and (ii) to other odorants paired with lexicosemantic labels (associative learning). Second, the same participants were tested in a brain imaging study (fMRI) measuring hemodynamic responses to learned odors presented in both the perceptual and associative learning conditions...
September 12, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28899618/smell-and-taste-in-the-preterm-infant
#20
Frank H Bloomfield, Tanith Alexander, Mariana Muelbert, Friederike Beker
Olfaction and gustation are critical for the enjoyment of food but also have important metabolic roles, initiating the cephalic phase response that sets in train secretion of hormones important for metabolism and digestion before any food is actually ingested. Smell and taste receptors are functional in the fetus and there is evidence for antenatal learning of odours. Despite enteral nutrition and metabolism being major issues in the care of very preterm infants, often little consideration is given to the potential role of smell and taste in supporting these processes, or in the role they may have in encoding hypothalamic circuitry in a way that promotes healthy metabolism in the post‑neonatal period...
September 9, 2017: Early Human Development
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