keyword
MENU ▼
Read by QxMD icon Read
search

Data analysis

keyword
https://www.readbyqxmd.com/read/29668080/control-of-the-ethylene-signaling-pathway-prevents-plant-defenses-during-intracellular-accommodation-of-the-rhizobia
#1
Fathi Berrabah, Thierry Balliau, El Hosseyn Aït-Salem, Jeoffrey George, Michel Zivy, Pascal Ratet, Benjamin Gourion
Massive intracellular populations of symbiotic bacteria, referred to as rhizobia, are housed in legume root nodules. Little is known about the mechanisms preventing the development of defense in these organs although genes such as symCRK and DNF2 of the model legume Medicago truncatula are required for this control after rhizobial internalization in host nodule cells. Here we investigated the molecular basis of the symbiotic control of immunity. Proteomic analysis was performed to compare functional (wild-type) and defending nodules (symCRK)...
April 18, 2018: New Phytologist
https://www.readbyqxmd.com/read/29668079/co-culture-of-adipose-derived-stem-cells-and-chondrocytes-on-three-dimensionally-printed-bioscaffolds-for-craniofacial-cartilage-engineering
#2
Robert J Morrison, Hassan B Nasser, Khaled N Kashlan, David A Zopf, Derek J Milner, Colleen L Flanangan, Matthew B Wheeler, Glenn E Green, Scott J Hollister
OBJECTIVES/HYPOTHESIS: Reconstruction of craniofacial cartilagenous defects are among the most challenging surgical procedures in facial plastic surgery. Bioengineered craniofacial cartilage holds immense potential to surpass current reconstructive options, but limitations to clinical translation exist. We endeavored to determine the viability of utilizing adipose-derived stem cell-chondrocyte co-culture and three-dimensional (3D) printing to produce 3D bioscaffolds for cartilage tissue engineering...
April 18, 2018: Laryngoscope
https://www.readbyqxmd.com/read/29668062/long-term-outcomes-and-molecular-analysis-of-a-large-cohort-of-patients-with-46-xy-disorder-of-sex-development-due-to-partial-gonadal-dysgenesis
#3
Nathalia Lisboa Gomes, Antônio Marcondes Lerário, Aline Machado Zamboni, Daniela Rodrigues de Moraes, Thatiana Evilen da Silva, Ivo Jorge Prado Arnhold, Rafael Loch Batista, José Antônio Diniz Faria Júnior, Elaine F Costa, Mirian Y Nishi, Marlene Inacio, Sorahia Domenice, Berenice B Mendonca
BACKGROUND: Follow-up data on patients with 46,XY partial gonadal dysgenesis (PGD) until adulthood are scarce, making information on prognosis difficult. OBJECTIVE: To analyse the long-term outcomes of patients with 46,XY PGD regarding testosterone production, germ cell tumour risk, genotype, and psychosexual adaptation. METHODS: A retrospective longitudinal study of 33 patients (20 assigned male and 13 patients assigned female at birth). Molecular diagnosis was performed by Sanger sequencing or by targeted massively parallel sequencing of 63 genes related to disorders of sex development (DSDs)...
April 18, 2018: Clinical Endocrinology
https://www.readbyqxmd.com/read/29668047/miniaturization-of-the-microsuspension-salmonella-microsome-assay-in-agar-microplates
#4
José Ricardo R M Zwarg, Daniel A Morales, Bianca S Maselli, Werner Brack, Gisela A Umbuzeiro
The Salmonella/microsome assay (Ames test) is the most widely used mutagenicity test for the evaluation of pure chemicals and environmental samples. There are several versions of protocols available in the literature, including those that reduce the amount of sample needed for testing with liquid and agar media. The microsuspension version of the Salmonella/microsome assay is more sensitive than the standard protocol. It is performed using 5-times concentrated bacteria and less sample and S9 mixture, but still uses conventional Petri dishes (90 × 15 mm)...
April 18, 2018: Environmental and Molecular Mutagenesis
https://www.readbyqxmd.com/read/29668028/reallocating-time-between-sleep-sedentary-and-active-behaviours-associations-with-obesity-and-health-in-canadian-adults
#5
Rachel C Colley, Isabelle Michaud, Didier Garriguet
BACKGROUND: Moderate-to-vigorous physical activity (MVPA) and sleep are positively associated with adults' health, while the association with sedentary behaviour (SED) is negative. Light-intensity physical activity (LPA) is emerging as an independent predictor of improved cardiovascular health. The health impacts of each of these factors have been examined in isolation, but interest has increased in associations between health and movement behaviours collectively. DATA AND METHODS: This analysis examines how reallocating time between movement behaviours is associated with obesity and with self-rated general and mental health...
April 18, 2018: Health Reports
https://www.readbyqxmd.com/read/29667943/factors-associated-with-initiation-of-biologics-in-patients-with-axial-spondyloarthritis-in-an-urban-asian-city-a-prespond-study
#6
Wan Yu Png, Yu Heng Kwan, Yi Xuan Lee, Ka Keat Lim, Eng Hui Chew, Nai Lee Lui, Chuen Seng Tan, Julian Thumboo, Truls Østbye, Warren Fong
OBJECTIVE: The aim of this study was to examine if patients' sociodemographic, clinical characteristics, and patient-reported outcomes were associated with biologics initiation in patients with axial spondyloarthritis in Singapore. METHODS: Data from a dedicated registry from a tertiary referral center in Singapore from January 2011 to July 2016 were used. Initiation of first biologics was the main outcome of interest. Logistic regression analyses were used to explore the association of various factors on biologics initiation...
April 5, 2018: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/29667936/automated-algorithms-for-detecting-sleep-period-time-using-a-multi-sensor-pattern-recognition-activity-monitor-from-24-h-free-living-data-in-older-adults
#7
Veronica Cabanas-Sanchez, Sara Higueras-Fresnillo, Miguel Ángel De La Camara, Oscar L Veiga, David Martinez-Gomez
The aims of the present study were: (i) to develop automated algorithms to identify the sleep period time in 24-h data from the Intelligent Device for Energy Expenditure and Activity (IDEEA) in older adults, and (ii) to analyze the agreement of these algorithms to identify the sleep period time as compared to self-reported data and expert visual analysis of accelerometer raw data.
 Approach. This study comprised 50 participants, aged 65 to 85 years. Fourteen automated algorithms were developed. Participants reported their bedtime and wake time in the days wearing the device...
April 18, 2018: Physiological Measurement
https://www.readbyqxmd.com/read/29667932/fused-data-transrectal-eit-for-prostate-cancer-imaging
#8
Ethan K Murphy, Xiaotian Wu, Ryan J Halter
OBJECTIVE: Prostate cancer is a significant problem affecting 1 in 7 men. Unfortunately, the diagnostic gold-standard of ultrasound-guided biopsy misses 10-30% of all cancers. The objective of this study was to develop an Electrical Impedance Tomography (EIT) approach that has the potential to image the entire prostate using multiple impedance measurements recorded between electrodes integrated onto an end-fired transrectal ultrasound (TRUS) device and a biopsy probe (BP). APPROACH: Simulations and sensitivity analyses were used to investigate the best combination of electrodes, and measured tank experiments were used to evaluate a fused-data transrectal EIT (fd-TREIT) and BP approach...
April 18, 2018: Physiological Measurement
https://www.readbyqxmd.com/read/29667904/establishing-cut-offs-for-urine-erythrocyte-and-leukocyte-dipstick-tests
#9
Yousun Chung, Dae-Hyun Ko, Jungwon Hyun, Hyun Soo Kim, Min-Jeong Park, Dong Hoon Shin
Urine erythrocyte (Ery) and leukocyte (Leu) dipstick tests are essential for detecting microhematuria and urinary tract infection. Currently, there is no suggestion for establishing the cut-off limits in an ordinal scale test. This study aimed to establish the cut-off limits for urine Ery and Leu dipstick tests via probit regression. From 1 January 2016 to 30 June 2016, laboratory data were collected from patients at one teaching hospital whose specimen had analytical results from both a urine dipstick test and an automated urine particle analyzer...
April 18, 2018: Scandinavian Journal of Clinical and Laboratory Investigation
https://www.readbyqxmd.com/read/29667900/outcomes-of-emergency-thoracotomy-for-trauma-in-a-general-hospital-in-singapore
#10
Isabelle Rui Wen Yoong, Gregory Heng, Sachin Mathur, Woan Wui Lim, Tiong Thye Goo
Background An emergency thoracotomy can be performed either immediately at the site of trauma or in the emergency department or operating room for resuscitation of patients in extremis or life-saving treatment for patients with thoracic injury. It remains a procedure associated with high mortality rates, and there is a paucity of data from Asia. This study analyzed our six-year experience of emergency trauma thoracotomy in an acute general hospital in Singapore. Methods This retrospective analysis was based on experience in a single institution with all emergency trauma thoracotomies performed by general surgeons...
January 1, 2018: Asian Cardiovascular & Thoracic Annals
https://www.readbyqxmd.com/read/29667897/narrative-roles-among-contact-versus-noncontact-sexual-offenders
#11
Emma Hamilton, Delida Sanchez
The current study explored narrative roles among individuals convicted of a sexual offense. Narrative roles in a criminal context are defined as specific personal accounts utilized by offenders to justify illegal behavior. The chosen theoretical framework recognized four primary offender roles: Revengeful Mission/Romantic Quest, Professional, Victim, and Tragic Hero. A total of 23 interviews were conducted with individuals convicted of a sexual offense ( n = 11 contact, n = 12 noncontact) to explore and compare narrative roles between contact and noncontact offenders...
April 1, 2018: Sexual Abuse: a Journal of Research and Treatment
https://www.readbyqxmd.com/read/29667892/ct-colonography-performance-for-the-detection-of-polyps-and-cancer-in-adults-%C3%A2-65-years-old-systematic-review-and-meta-analysis
#12
Perry J Pickhardt, Loredana Correale, Silvia Delsanto, Daniele Regge, Cesare Hassan
OBJECTIVE: We sought to perform a systematic review and meta-analysis of published CT colonography (CTC) studies assessing lesion detection in senior-age (≥ 65 years old) cohorts. MATERIALS AND METHODS: We conducted a systematic review of CTC studies published between January 1994 and August 2017 containing data on senior-age adults. The primary endpoint was the CTC-positive rate for large colorectal polyps (≥ 10 mm) and masses. Secondary endpoints included lesions ≥ 6 mm, proven advanced neoplasia, and colorectal cancer (CRC)...
April 18, 2018: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/29667882/new-doppler-imaging-technique-for-assessing-angiogenesis-in-breast-tumors-correlation-with-immunohistochemically-analyzed-microvessels-density
#13
Sewha Kim, Hye Jin Lee, Kyung Hee Ko, Ah Young Park, Jieun Koh, Hae Kyoung Jung
Background Microvessel density (MVD) is associated with grade and prognosis in breast tumors. However, conventional color Doppler flow (CDF) imaging has been limited to represent MVD of breast tumors. Purpose To evaluate whether a new Doppler imaging technique (AngioPLUS) can represent MVD of breast tumors. Material and Methods The institutional review board approved this retrospective study, and patients' informed consent was waived. CDF and AngioPLUS were available in pathologically confirmed 55 breast tumors of 53 women...
January 1, 2018: Acta Radiologica
https://www.readbyqxmd.com/read/29667880/motion-artifacts-lesion-type-and-parenchymal-enhancement-in-breast-mri-what-does-really-influence-diagnostic-accuracy
#14
Paola Clauser, Matthias Dietzel, Michael Weber, Clemens G Kaiser, Pascal At Baltzer
Background Motion artifacts can reduce image quality of breast magnetic resonance imaging (MRI). There is a lack of data regarding their effect on diagnostic estimates. Purpose To evaluate factors that potentially influence readers' diagnostic estimates in breast MRI: motion artifacts; amount of fibroglandular tissue; background parenchymal enhancement; lesion size; and lesion type. Material and Methods This Institutional Review Board-approved, retrospective, cross-sectional, single-center study included 320 patients (mean age = 55...
January 1, 2018: Acta Radiologica
https://www.readbyqxmd.com/read/29667858/longitudinal-analysis-of-varicella-zoster-virus-specific-antibodies-in-systemic-lupus-erythematosus-no-association-with-subclinical-viral-reactivations-or-lupus-disease-activity
#15
C Rondaan, C C van Leer, S van Assen, H Bootsma, K de Leeuw, S Arends, N A Bos, J Westra
Systemic lupus erythematosus (SLE) patients are at high risk of herpes zoster. Previously, we found increased immunoglobulin (Ig)G levels against varicella-zoster virus (VZV) in SLE patients compared to controls, while antibody levels against diphtheria and cellular immunity to VZV were decreased. We aimed to test our hypothesis that increased VZV-IgG levels in SLE result from subclinical VZV reactivations, caused by stress because of lupus disease activity or immunosuppressive drug use. Methods Antibody levels to VZV (IgG, IgA, IgM), total IgG and VZV-DNA were longitudinally determined in the serum of 34 SLE patients, using enzyme-linked immunosorbent assay and polymerase chain reaction...
January 1, 2018: Lupus
https://www.readbyqxmd.com/read/29667857/determining-risk-factors-that-increase-hospitalizations-in-patients-with-systemic-lupus-erythematosus
#16
D Li, H M Madhoun, W N Roberts, W Jarjour
Introduction Systemic lupus erythematosus (SLE) is a complex disease that is associated with significant mortality and an increased risk of hospitalization. Several validated instruments are available to measure disease activity in SLE patients. However, these instruments were not designed to screen for SLE patients at an increased risk of hospitalization. These instruments also fail to incorporate some data that are easily obtainable from electronic health records, such as the frequency of missed outpatient appointments...
January 1, 2018: Lupus
https://www.readbyqxmd.com/read/29667821/antibacterial-dimeric-acylphloroglucinols-from-hypericum-japonicum
#17
Yan-Ping Li, Kun Hu, Xing-Wei Yang, Gang Xu
Nine dimeric acylphloroglucinols, including the new hyperjaponicols A-D (1-4), were isolated from the whole plant of Hypericum japonicum. The new structures were determined by the interpretation of NMR and MS data, and the relative configuration of the known compound, sarothralen C (5), was reassigned via NMR spectroscopic analysis and single-crystal X-ray diffraction data. The inhibitory activities of the isolates against four bacterial strains were evaluated, and compounds 1-4, 6, and 7 exhibited significant antibacterial activity with MIC values of 0...
April 18, 2018: Journal of Natural Products
https://www.readbyqxmd.com/read/29667783/phap1-promotes-glioma-cell-proliferation-by-regulating-the-akt-p27-stathmin-pathway
#18
Manyi Xie, Zhe Ji, Yaxing Bao, Yufu Zhu, Yang Xu, Lei Wang, Shangfeng Gao, Zhiyi Liu, Zilu Tian, Qingming Meng, Hengliang Shi, Rutong Yu
PHAP1 (Putative HLA-DR-associated protein 1), also termed acidic leucine-rich nuclear phosphoprotein 32A (ANP32A), Phosphoprotein 32 (pp32) or protein phosphatase 2A inhibitor (I1PP2A), is a multifunctional protein aberrantly expressed in multiple types of human cancers. However, its expression pattern and clinical relevance in human glioma remain unknown. In this study, Western blotting and immunohistochemistry analysis demonstrated PHAP1 protein was highly expressed in glioma patients, especially in those with high-grade disease...
April 18, 2018: Journal of Cellular and Molecular Medicine
https://www.readbyqxmd.com/read/29667782/hypofolins-a-l-ent-labdane-diterpenoids-from-the-roots-of-hypoestes-phyllostachya-pink-splash
#19
Bin Cheng, Lin-Fen Ding, Tong Yan, Zhang-Qiao Xie, Zhi-Jun Zhang, Liu-Dong Song, Xing-De Wu, Qin-Shi Zhao
Twelve new ent-labdane diterpenoids, hypofolins A-F (1-6) and hypofolins G-L (7a/7b, 8a/8b, and 9a/9b), were isolated from the roots of Hypoestes phyllostachya "Pink Splash". Their structures were elucidated by extensive 1D and 2D NMR spectroscopic and HRMS data. The absolute configurations of 1, 2, 5, and 7a/7b were determined by single crystal X-ray diffraction and ECD analysis, as well as chemical transformations. Compounds 7a/7b, 8a/8b, and 9a/9b were isolated as three pairs of interconverting mixture of two isomers between ketone and hemiketal types...
April 18, 2018: Chemistry & Biodiversity
https://www.readbyqxmd.com/read/29667705/intellectual-disability-in-cerebral-palsy-a-population-based-retrospective-study
#20
Susan M Reid, Elaine M Meehan, Sarah J Arnup, Dinah S Reddihough
AIM: A population-based observational study design was used to describe the epidemiology of intellectual disability in cerebral palsy (CP) in terms of clinical and neuroimaging associations, and to report the impact of intellectual disability on utilization of health services and length of survival. METHOD: Population CP registry data were used to retrospectively assess the frequency of intellectual disability and strength of associations between intellectual disability and mobility, epilepsy, vision, hearing, communication, and neuroimaging patterns (n=1141)...
April 18, 2018: Developmental Medicine and Child Neurology
keyword
keyword
13451
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"