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https://www.readbyqxmd.com/read/28528531/diversity-and-distribution-of-ticks-from-domestic-ruminants-in-lebanon
#1
Mayssaa Fawaz Dabaja, Maria Tempesta, Ali Bayan, Gesualdo Vesco, Grazia Greco, Grazia Greco, Alessandra Torina, Valeria Blanda, Francesco La Russa, Salvatore Scimeca, Rossella Lelli, Mohamad Ezzedine, Hussein Mortada, Didier Raoult, Pierre Edouard Fournier, Mohamad Mortada
Ticks (Acari: Ixodidae) are ectoparasites infesting livestock in every geographic area in the world and they are vectors of several viral, bacterial, and protozoan pathogens to animals and humans worldwide. A deep knowledge of the geographical distribution of these arthropods would have a key role in the control of tick-borne diseases. Few data are available about tick presence in domestic ruminants in Lebanon. The study aimed at providing an analysis of tick presence and distribution in Lebanon. Ticks were collected from cattle, sheep, and goats farms distributed in 6 Lebanese provinces between June and September 2014...
April 11, 2017: Veterinaria Italiana
https://www.readbyqxmd.com/read/28528495/dairy-farm-demographics-and-management-factors-that-played-a-role-in-the-re-emergence-of-brucellosis-on-dairy-cattle-farms-in-fiji
#2
Andrew Tukana, B Gummow
Little is published on risk factors associated with bovine brucellosis in Pacific island communities. The 2009 re-emergence of bovine brucellosis in Fiji enabled us to do an interview-based questionnaire survey of 81 farms in the Wainivesi locality of the Tailevu province on the main island of Fiji to investigate what risk factors could have played a role in the re-emergence of the disease. The survey was conducted on 68 farms that had no positive cases of bovine brucellosis and on 13 farms in the same area where cattle had returned a positive result to the Brucella Rose Bengal test...
May 20, 2017: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/28528493/clinical-investigation-of-chronic-subdural-hematoma-with-impending-brain-herniation-on-arrival
#3
Hiroaki Matsumoto, Hiroaki Hanayama, Takashi Okada, Yasuo Sakurai, Hiroaki Minami, Atsushi Masuda, Shogo Tominaga, Katsuya Miyaji, Ikuya Yamaura, Yasuhisa Yoshida
Chronic subdural hematoma (CSDH) with brain herniation signs is rarely seen in the emergent department. As such, there are few cumulative data to analyze such cases. In this study, we evaluated the clinical features, risk factors, and rates of completion with impending brain herniation on arrival in a cohort study. We analyzed 492 consecutive patients with CSDH between January 2010 and October 2015. First, we analyzed the clinical factors and compared them between patients with or without brain herniation signs on admission...
May 20, 2017: Neurosurgical Review
https://www.readbyqxmd.com/read/28528481/consent-an-event-or-a-memory-in-lumbar-spinal-surgery-a-multi-centre-multi-specialty-prospective-study-of-documentation-and-patient-recall-of-consent-content
#4
William B Lo, Ciaran P McAuley, Martin J Gillies, Patrick J Grover, Erlick A C Pereira
STUDY DESIGN: Prospective, multi-centre, multi-specialty medical notes review and patient interview. PURPOSE: The consenting process is an important communication tool which also carries medico-legal implications. While written consent is a pre-requisite before spinal surgery in the UK, the standard and effectiveness of the process have not been assessed previously. This study assesses standard of written consent for elective lumbar decompressive surgery for degenerative disc disease across different regions and specialties in the UK; level of patient recall of the consent content; and identifies factors which affect patient recall...
May 20, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28528452/tumor-suppressor-protein-p53-exerts-negative-transcriptional-regulation-on-human-sodium-iodide-symporter-gene-expression-in-breast-cancer
#5
Madhura G Kelkar, Bhushan Thakur, Abhishek Derle, Sushmita Chatterjee, Pritha Ray, Abhijit De
PURPOSE: Aberrant expression of human sodium iodide symporter (NIS) in breast cancer (BC) is well documented but the transcription factors (TF) regulating its aberrant expression is poorly known. We identify the presence of three p53 binding sites on the human NIS promoter sequence by conducting genome-wide TF analysis, and further investigate their regulatory role. METHODS: The differences in transcription and translation were measured by real-time PCR, luciferase reporter assay, site-directed mutagenesis, in vivo optical imaging, and chromatin immunoprecipitation...
May 20, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28528451/influence-of-comorbidity-on-chemotherapy-use-for-early-breast-cancer-systematic-review-and-meta-analysis
#6
REVIEW
Melissa J Edwards, Ian D Campbell, Ross A Lawrenson, Marion J Kuper-Hommel
PURPOSE: Patients with early breast cancer and coexistent comorbidities generally experience worse prognosis which may be in part related to inferior treatment. Randomised data on chemotherapy use and tolerance in comorbid patients are limited. We aimed to review the available literature regarding the use of chemotherapy in such patients. METHODS: A systematic search of databases was performed for English-language articles evaluating the impact of comorbidity on chemotherapy use for early breast cancer...
May 20, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28528404/a-direct-comparison-of-the-effects-of-the-antiretroviral-drugs-stavudine-tenofovir-and-the-combination-lopinavir-ritonavir-on-bone-metabolism-in-a-rat-model
#7
M M Conradie, M van de Vyver, E Andrag, M Conradie, W F Ferris
Antiretroviral (ARV) treatment may induce metabolic complications in HIV patients on long-term therapy that can affect bone health. In this study, the effects of the ARVs Stavudine (d4T), Tenofovir (TDF) and Lopinavir/ritonavir (LPV/r) on bone metabolism and lipodystrophy were directly compared in rats to negate the consequences of HIV-associated confounding factors. Healthy 12-14-week-old male Wistar rats (n = 40) were divided into four treatment groups and received an oral animal equivalent dose of either Stavudine (6...
May 20, 2017: Calcified Tissue International
https://www.readbyqxmd.com/read/28528372/associations-between-ptpn22-and-tlr9-polymorphisms-and-systemic-lupus-erythematosus-a-comprehensive-meta-analysis
#8
Li-Ya Hu, Zhi Cheng, Bo Zhang, Qiong Yin, Xiao-Wei Zhu, Pian-Pian Zhao, Ming-Yu Han, Xiao-Bo Wang, Hou-Feng Zheng
Previous studies have explored the relationship of PTPN22 and TLR9 polymorphisms with systemic lupus erythematosus (SLE). In consideration of the population stratification, conflicting results and updating data, we conducted a comprehensive meta-analysis, which consists of a total of 17 research articles (9120 cases and 11,724 controls) for PTPN22 and 20 articles (including up to 2808 cases and 3386 controls) for TLR9. Significant association was verified between PTPN22 rs2476601 and SLE in the overall population (OR = 1...
May 20, 2017: Archives of Dermatological Research
https://www.readbyqxmd.com/read/28528323/c-graph-a-validated-scoring-system-for-early-stratification-of-neurologic-outcome-after-out-of-hospital-cardiac-arrest-treated-with-targeted-temperature-management
#9
Erich L Kiehl, Alex M Parker, Ralph M Matar, Matthew F Gottbrecht, Michelle C Johansen, Mark P Adams, Lori A Griffiths, Steven P Dunn, Katherine L Bidwell, Venu Menon, Kyle B Enfield, Lawrence W Gimple
BACKGROUND: Out-of-hospital cardiac arrest (OHCA) results in significant morbidity and mortality, primarily from neurologic injury. Predicting neurologic outcome early post-OHCA remains difficult in patients receiving targeted temperature management. METHODS AND RESULTS: Retrospective analysis was performed on consecutive OHCA patients receiving targeted temperature management (32-34°C) for 24 hours at a tertiary-care center from 2008 to 2012 (development cohort, n=122)...
May 20, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28528311/rapid-screening-and-identification-of-chemical-hazards-in-surface-and-drinking-water-using-high-resolution-mass-spectrometry-and-a-case-control-filter
#10
Sarit L Kaserzon, Amy L Heffernan, Kristie Thompson, Jochen F Mueller, Maria Jose Gomez Ramos
Access to clean, safe drinking water poses a serious challenge to regulators, and requires analytical strategies capable of rapid screening and identification of potentially hazardous chemicals, specifically in situations when threats to water quality or security require rapid investigations and potential response. This study describes a fast and efficient chemical hazard screening strategy for characterising trace levels of polar organic contaminants in water matrices, based on liquid chromatography high resolution mass spectrometry with post-acquisition 'case-control' data processing...
May 12, 2017: Chemosphere
https://www.readbyqxmd.com/read/28528291/the-association-of-lifetime-physical-inactivity-with-bladder-and-renal-cancer-risk-a-hospital-based-case-control-analysis
#11
Rikki Cannioto, John Lewis Etter, Lauren Beryl Guterman, Janine M Joseph, Nicholas R Gulati, Kristina L Schmitt, Michael J LaMonte, Ryan Nagy, Albina Minlikeeva, James Brian Szender, Kirsten B Moysich
OBJECTIVES: Recreational physical inactivity has been gaining recognition as an independent epidemiological exposure of interest in relation to cancer endpoints due to evidence suggesting that it may associate with cancer independent of obesity. In the current analyses, we examined the associations of lifetime recreational physical inactivity with renal and bladder cancer risk. METHODS: In this hospital-based case-control study, we identified N=160 renal cancer patients, N=208 bladder cancer patients, and N=766 age frequency-matched controls without cancer...
May 18, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28528281/risk-of-stroke-among-patients-with-borderline-personality-disorder-a-nationwide-longitudinal-study
#12
Mu-Hong Chen, Ju-Wei Hsu, Ya-Mei Bai, Tung-Ping Su, Cheng-Ta Li, Wei-Chen Lin, Shih-Jen Tsai, Wen-Han Chang, Tzeng-Ji Chen, Kai-Lin Huang
BACKGROUND: Previous studies suggested that patients with borderline personality disorder (BPD) had a higher prevalence of stroke-related risk factors, such as hypertension, dyslipidemia, and diabetes mellitus. But, the association between BPD and subsequent stroke has been rarely investigated. METHODS: Using the Taiwan National Health Insurance Research Database, 5969 borderline patients aged 18 years and older and 23,876 age-and sex-matched controls were enrolled between 2002 and 2009, and followed up to the end of 2011 to identify the development of stroke...
May 8, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28528223/the-mediating-role-of-sleep-quality-on-the-relationship-between-perceived-stress-and-depression-among-the-elderly-in-urban-communities-a-cross-sectional-study
#13
Y Liu, T Li, L Guo, R Zhang, X Feng, K Liu
OBJECTIVE: This study aims to investigate the relationship between perceived stress, sleep quality, and depression among the elderly in urban communities, and further to determine whether sleep quality can serve as a mediator among the elderly in urban communities. STUDY DESIGN: A cross-sectional survey. METHODS: Between May and July in 2015, we conducted a cross-sectional survey among 1050 community residents aged ≥60 years from Liaoning province, China...
May 18, 2017: Public Health
https://www.readbyqxmd.com/read/28528218/laboratory-studies-of-ultrasonic-wave-response-of-fractures-with-different-lengths-anisotropy-characteristics-and-coda-analysis
#14
D Wang, S L Qu, Q Zhao, X Y Yin, F Zhou
Ultrasonic wave propagation in a synthetic medium with different scale fractures is investigated through the physics modeling research. The experiment model consisting of two layers, the first layer is divided into four fractured blocks with a constant fracture density but different dimension and a block without fractures as the reference region. The velocity and reflected amplitude of wave derived from the wide azimuth data processing are anisotropic due to the fractured layer. Coda wave characteristics versus offset and azimuth are obviously different for varying fracture scales...
May 13, 2017: Ultrasonics
https://www.readbyqxmd.com/read/28528216/prognostic-factors-in-patients-treated-with-surgery-for-brain-metastases-a-single-center-retrospective-analysis-of-125-patients
#15
Zhenghao Liu, Bingxi Lei, Meiguang Zheng, Zhongjun Li, Shuaibin Huang, Yuefei Deng
BACKGROUD: Brain metastases are the most common malignant intracranial tumors,however, the prognosis of patients is still poor despite multiple treatment have been applicated.The aim of this study was to analyse parameters influence overall survival from patient, tumor and treatment. Summarized characteristics of long-time(>2 years) survivors furtherly. MATERIALS AND METHODS: In total, clinical data of 125patients between 2004 and 2015 were collected and the parameters from patients, tumor and treatment were evaluated...
May 17, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28528179/factors-related-to-a-negative-birth-experience-a-mixed-methods-study
#16
Lena Henriksen, Elisabeth Grimsrud, Berit Schei, Mirjam Lukasse
OBJECTIVE: this study aimed to explore factors associated with a negative childbirth experience including descriptions from women themselves. DESIGN: we performed a mixed methods study based on data from the Norwegian cohort of the Bidens study, including a total of 1352 multiparous women. Quantitative information was analysed in addition to thematic analysis of 103 free-text comments provided by women with a prior negative childbirth experience. KEY FINDINGS: the total prevalence of a negative birth experience was 21...
May 8, 2017: Midwifery
https://www.readbyqxmd.com/read/28528147/variability-and-reproducibility-of-segmental%C3%A2-longitudinal-strain-measurement-a-report-from-the-eacvi-ase-strain-standardization-task%C3%A2-force
#17
Oana Mirea, Efstathios D Pagourelias, Jurgen Duchenne, Jan Bogaert, James D Thomas, Luigi P Badano, Jens-Uwe Voigt
OBJECTIVES: In this study, we compared left ventricular (LV) segmental strain measurements obtained with different ultrasound machines and post-processing software packages. BACKGROUND: Global longitudinal strain (GLS) has proven to be a reproducible and valuable tool in clinical practice. Data about the reproducibility and intervendor differences of segmental strain measurements, however, are missing. METHODS: We included 63 volunteers with cardiac magnetic resonance-proven infarct scar with segmental LV function ranging from normal to severely impaired...
May 12, 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28528118/calcium-supplementation-decreases-bcp-induced-inflammatory-processes-in-blood-cells-through-the-nlrp3-inflammasome-down-regulation
#18
Patricia Lagadec, Thierry Balaguer, Florian Boukhechba, Grégory Michel, Sébastien Bouvet-Gerbettaz, Jean-Michel Bouler, Jean-Claude Scimeca, Nathalie Rochet
Interaction of host blood with biomaterials is the first event occurring after implantation in a bone defect. This study aimed at investigating the cellular and molecular consequences arising at the interface between whole blood and biphasic calcium phosphate (BCP) particles. We observed that, due to calcium capture, BCP inhibited blood coagulation, and that this inhibition was reversed by calcium supplementation. Therefore, we studied the impact of calcium supplementation on BCP effects on blood cells. Comparative analysis of BCP and calcium supplemented-BCP (BCP/Ca) effects on blood cells showed that BCP as well as BCP/Ca induced monocyte proliferation, as well as a weak but significant hemolysis...
May 17, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28528105/vulnerability-of-global-food-production-to-extreme-climatic-events
#19
F Yeni, H Alpas
It is known that the frequency, intensity or duration of the extreme climatic events have been changing substantially. The ultimate goal of this study was to identify current vulnerabilities of global primary food production against extreme climatic events, and to discuss potential entry points for adaptation planning by means of an explorative vulnerability analysis. Outcomes of this analysis were demonstrated as a composite index where 118 country performances in maintaining safety of food production were compared and ranked against climate change...
June 2017: Food Research International
https://www.readbyqxmd.com/read/28528096/analysis-of-domestic-refrigerator-temperatures-and-home-storage-time-distributions-for-shelf-life-studies-and-food-safety-risk-assessment
#20
Anna Roccato, Mieke Uyttendaele, Jeanne-Marie Membré
In the framework of food safety, when mimicking the consumer phase, the storage time and temperature used are mainly considered as single point estimates instead of probability distributions. This singlepoint approach does not take into account the variability within a population and could lead to an overestimation of the parameters. Therefore, the aim of this study was to analyse data on domestic refrigerator temperatures and storage times of chilled food in European countries in order to draw general rules which could be used either in shelf-life testing or risk assessment...
June 2017: Food Research International
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