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https://www.readbyqxmd.com/read/29685637/mechanisms-of-sustained-long-term-weight-loss-after-rygb-%C3%AE-msh-is-a-key-factor
#1
Gisele Farias, Bárbara Dal Molin Netto, Katia Cristina Boritza, Solange Cravo Bettini, Ana Raimunda Dâmaso, Alexandre Coutinho Teixeira de Freitas
No abstract text is available yet for this article.
April 17, 2018: Neuropeptides
https://www.readbyqxmd.com/read/29679605/circulating-cell-free-dna-in-patients-with-alveolar-echinococcosis
#2
Alice Baraquin, Eric Hervouet, Carine Richou, Pierre Flori, Paul Peixoto, Amel Azizi, Eric Delabrousse, Oleg Blagosklonov, Gerald Umhang, Solange Bresson-Hadni, Benoit Valot, Frédéric Grenouillet
Alveolar echinococcosis (AE) is a parasitic disease, due to Echinococcus multilocularis. Often compared to liver cancer, it develops by infiltration from its primary site to the surrounding tissue, and can then metastasize to other organs. Detection of circulating cell-free DNA (ccfDNA) is a useful analytical tool in oncology, for diagnosis, prognosis, and therapy monitoring. This study sought to investigate the presence of ccfDNA in patients with AE, and its potential usefulness for the evaluation of treatment efficiency...
April 18, 2018: Molecular and Biochemical Parasitology
https://www.readbyqxmd.com/read/29677533/proresolving-protein-annexin-a1-the-role-in-type-2-diabetes-mellitus-and-obesity
#3
Nathalia T Pietrani, Cláudia N Ferreira, Kathryna F Rodrigues, Luiza O Perucci, Fernanda S Carneiro, Adriana A Bosco, Marina C Oliveira, Solange S Pereira, Antônio L Teixeira, Jacqueline I Alvarez-Leite, Adaliene V Ferreira, Lirlândia P Sousa, Karina B Gomes
BACKGROUND: Annexin A1 (AnxA1) is a protein involved in inflammation resolution that might be altered in obesity-associated type 2 diabetes mellitus (DM), which is a chronic inflammatory disease. The aim of this study was to evaluate AnxA1 serum levels in individuals with and without DM stratified according to the body mass index (BMI), and the dynamic of AnxA1 expression in adipose tissue from humans with obesity and non-obesity. METHODS: Serum samples were obtained from 41 patients with DM (lean, overweight and obese) and 40 controls, and adipose tissue samples were obtained from 16 individuals with obesity (with or without DM), and 15 controls...
April 17, 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29668146/-adolescents-suffering-from-anorexia-nervosa-an-evidence-based-approach-of-the-parent-s-role-in-2018
#4
Sophie Vust, Solange Cook-Darzens, Françoise Lier, Anne-Emmanuelle Ambresin
A new paradigm in the management of adolescents with eating disorders promotes different treatment orientations aiming at increasing therapeutic effectiveness as well as offering a more integrated and coherent care for families. Particular attention is given to the process of refeeding to avoid the severe somatic sequelae of eating disorder and the risk of a chronic course for a disorder which is well known for its « addictive » power and influence. The parents and the need for a strong alliance with the healthcare team stand at the centre of this new paradigm...
April 18, 2018: Revue Médicale Suisse
https://www.readbyqxmd.com/read/29667435/clinical-and-surgical-risk-factors-for-consecutive-exotropia
#5
Sophie Bryselbout, Veronique Promelle, Florent Pracca, Solange Milazzo
INTRODUCTION: Consecutive exotropia is one of the complications of esotropia surgery. Its prevalence is estimated at 4%-27%. The aim of this study was to identify the risk factors for consecutive exotropia in the aftermath of surgical treatment of esotropia. METHODS: Seventy-four patients examined in our strabismus consultation for a consecutive exotropia from January 2010 to June 2016 were retrospectively included. The age of onset of esotropia, the presence of amblyopia, the age of esotropia surgery and chosen procedure, the refractive errors, the anomalies of ocular motility, the age of onset of the consecutive exotropia and its angle of deviation were reported...
April 1, 2018: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/29665954/candida-species-in-tchapalo-and-bangui-two-traditional-alcoholic-beverages-from-c%C3%A3-te-d-ivoire
#6
Laurence A N Egue, Florent K N'guessan, Solange Aka-Gbezo, Jean-Paul K M Bouatenin, Marina Koussemon-Camara
The increase of infections due to non-Candida albicans species made it very necessary to conduct adequate characterization to be able to identify the species of Candida isolated from traditional fermented foods. In this study, based on their hue on Candida Chromogenic Agar medium, a total of 136 yeast strains were isolated from tchapalo and bangui. Molecular identification based on PCR-RFLP of internal transcribed spacers of rDNA (ITS) and sequencing of the ITS and the D1/D2 regions allowed us to assign these isolates to seven species: Candida tropicalis, Candida inconspicua, Candida rugosa, Saccharomyces cerevisiae, Kluyveromyces marxianus, Hanseniaspora guilliermondii, Trichosporon asahii...
May 2018: Fungal Biology
https://www.readbyqxmd.com/read/29658968/comet-and-cytogenetic-tests-as-tools-for-evaluating-genomic-instability-in-seeds-of-oryza-sativa-l-and-phaseolus-vulgaris-l-from-gene-banks
#7
Alisson F Dantas, Renata M Lopes, Maria L Fascineli, Solange C B R José, Juliano G Pádua, Marcos A Gimenes, Cesar K Grisolia
This study aimed to assess the feasibility of comet and cytogenetic tests as tools for evaluating genomic instability in seeds of Oryza sativa L. (rice) and Phaseolus vulgaris (beans) L. from gene banks. Rice and beans were exposed to methyl methanesulfonate (MMS) as a reference DNA damaging agent. Seeds of two accessions of rice and beans were obtained from Embrapa Rice and Beans - Brazil. Seed groups were imbibed in three concentrations of MMS for three periods of time to carry out cytogenetic tests, and for one period for the comet test...
January 2018: Genetics and Molecular Biology
https://www.readbyqxmd.com/read/29649973/clinical-and-histological-evolution-after-de-novo-donor-specific-anti-human-leukocyte-antigen-antibodies-a-single-centre-retrospective-study
#8
Yassine Bouatou, Olivia Seyde, Solange Moll, Pierre-Yves Martin, Jean Villard, Sylvie Ferrari-Lacraz, Karine Hadaya
BACKGROUND: Donor-specific anti-human leukocyte antigen (HLA) antibodies (DSA) can be preformed or de novo (dn). Strategies to manage preformed DSA are well described, but data on the management and outcomes of dnDSA are lacking. METHODS: We performed a retrospective analysis of data from a single centre of the management and outcomes of 22 patients in whom a dnDSA was identified with contemporary and follow up biopsies. RESULTS: Evolution from baseline to follow up revealed a statistically significant loss of kidney function (estimated glomerular filtration rate: 45...
April 12, 2018: BMC Nephrology
https://www.readbyqxmd.com/read/29644883/in-vitro-toxicity-assessment-of-rivaroxaban-degradation-products-and-kinetic-evaluation-to-decay-process
#9
Nathalie R Wingert, Marcelo D Arbo, Gabriela Göethel, Bárbara da Costa, Louise F Altknecht, Solange C Garcia, Martin Steppe
Degradation kinetics of oral anticoagulant rivaroxaban (RIV) was assessed in acid and alkaline media and while exposed to UVC radiation. Among all stress conditions tested, kinetic degradation process was better described by a zero-order model. A stability indicating method was validated for the analysis of the anticoagulant RIV in tablets by high-performance liquid chromatography. Robustness was evaluated with a two-level Plackett-Burman experimental design. The effect of acute exposition of the human hepatoblastoma HepG2 cell line to RIV stressed samples (100 and 500 µM) was assessed through in vitro toxicity tests...
April 12, 2018: Drug and Chemical Toxicology
https://www.readbyqxmd.com/read/29626362/clinical-outcome-of-dental-procedures-among-renal-transplant-recipients
#10
Rubens Caliento, Dmitry José de Santana Sarmento, Solange Kobayashi-Velasco, Stella Núbia Coelho de Sá, Patrícia Pinheiro Shibutani, Marina Gallotini
AIMS: To compare outcomes of dental procedures among a group of renal transplant recipients who had received antibiotic prophylaxis (AP) before the procedure and another group that had not received AP. METHODS AND RESULTS: The records of all renal transplant patients treated at the Special Care Dentistry Center (SCDC) were assessed. Dental procedures documented in the records were classified as invasive or noninvasive. All dental procedures performed were compiled, and the prescription or nonprescription of prophylactic antibiotics, and the incidence and description of postoperative complications after invasive procedures were recorded...
April 6, 2018: Special Care in Dentistry
https://www.readbyqxmd.com/read/29622026/evidence-of-the-factors-that-influence-the-utilisation-of-kangaroo-mother-care-by-parents-with-low-birth-weight-infants-in-low-and-middle-income-countries-lmics-a-scoping-review-protocol
#11
Christina T Mathias, Solange Mianda, Themba G Ginindza
BACKGROUND: The Sustainable Development Goal (SDG) 3 emphasises on reducing neonatal deaths caused by low birth weight (LBW) complications by the implementation and utilisation of Kangaroo Mother Care (KMC) in low- and middle-income countries (LMICs). Despite the empirical evidence of KMC optimising low-birth-weight infants' (LBWIs') survival, its advantages and the LMICs implementing the service, studies have shown that LBW infant deaths occurring in LMICs are largely contributing to global child mortality...
April 5, 2018: Systematic Reviews
https://www.readbyqxmd.com/read/29618196/the-course-of-intracranial-pressure-after-antipyretic-therapy-in-acute-brain-injury
#12
Edoardo Picetti, Patrizia Ceccarelli, Laura Malchiodi, Francesca Mensi, Solange Risolo, Franco Servadei, Corrado Iaccarino, Ilaria Rossi, Sandra Rossi
BACKGROUND: The present study was performed to evaluate intracranial pressure (ICP) variations after antipyretic therapy and their relationship to ICP at baseline (ICPbas) in acute brain injury (ABI) patients. METHODS: We completed a retrospective analysis on data derived from 2 previously published prospective observational studies. The first study involved 32 ABI patients and was performed to elucidate the cerebral and hemodynamic effects of intravenous (IV) paracetamol...
April 4, 2018: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/29608428/is-ayahuasca-an-option-for-the-treatment-of-crack-cocaine-dependence
#13
Joselaine Ida Cruz, Solange Aparecida Nappo
The low efficacy of crack cocaine addiction treatment available in Brazil has led Brazilian users to find alternatives to reduce drug consumption or even to reach abstinence. One of them is the use of entheogenic substances, like ayahuasca, an infusion obtained from two native plant species from the Amazon. The present report aimed to understand how crack cocaine users recover from drug addiction by consuming ayahuasca tea in a religious context. This is a qualitative study with a purposeful sample of 40 crack cocaine users, based on in-depth, semi-structured interviews...
April 2, 2018: Journal of Psychoactive Drugs
https://www.readbyqxmd.com/read/29602905/the-plant-defense-signal-galactinol-is-specifically-used-as-a-nutrient-by-the-bacterial-pathogen-agrobacterium-fabrum
#14
Thibault Meyer, Armelle Vigouroux, Magali Aumont-Niçaise, Gilles Comte, Ludovic Vial, Celine Lavire, Solange Morera
The bacterial plant pathogen Agrobacterium fabrum uses periplasmic binding proteins (PBPs) along with ABC transporters to import a wide variety of plant molecules as nutrients. Nonetheless, how A. fabrum acquires plant metabolites is incompletely understood. Using genetic approaches and affinity measurements, we identified here the PBP MelB and its transporter as being responsible for the uptake of the raffinose family of oligosaccharides (RFOs), which are the most widespread Dgalactose containing oligosaccharides in higher plants...
March 30, 2018: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/29597255/in-vitro-anti-toxoplasma-gondii-and-antimicrobial-activity-of-amides-derived-from-cinnamic-acid
#15
Graziela Rangel Silveira, Karoline Azerêdo Campelo, Gleice Rangel Silveira Lima, Lais Pessanha Carvalho, Solange Silva Samarão, Olney Vieira-da-Motta, Leda Mathias, Carlos Roberto Ribeiro Matos, Ivo José Curcino Vieira, Edesio José Tenório de Melo, Edmilson José Maria
Most cinnamic acids, their esters, amides, aldehydes, and alcohols present several therapeutic actions through anti-inflammatory, antitumor, and inhibitory activity against a great variety of microorganisms. In this work, eight amines derived from cinnamic acid were synthesized and tested against host cells infected with Toxoplasma gondii and the bacteria Escherichia coli, Pseudomonas aeruginosa, Staphylococcus epidermidis, and three strains of Staphylococcus aureus . Compounds 3 and 4 showed the best result against intracellular T...
March 28, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29594059/severe-inflammatory-ophthalmopathy-in-a-euthyroid-patient-during-nivolumab-treatment
#16
Pauline Campredon, Philippe Imbert, Céline Mouly, Solange Grunenwald, Julien Mazières, Philippe Caron
Introduction: Nivolumab is a promising treatment in patients with advanced malignancies. Among immune-related adverse events, autoimmune thyroid disorders are frequently reported. Patient: A 61-year-old male patient had no history of familial or personal thyroid disease. In 2012, this patient, a heavy smoker, presented with non-small-cell lung cancer that was treated with radiotherapy and chemotherapy. In 2015, the cancer progressed with cervical compressive symptoms, and the patient was treated with nivolumab...
March 2018: European Thyroid Journal
https://www.readbyqxmd.com/read/29580985/tributyltin-role-on-the-serotonin-and-histamine-receptors-in-human-umbilical-artery
#17
Solange Glória, João Marques, Joana Feiteiro, Helena Marcelino, Ignacio Verde, Elisa Cairrão
Some studies in animals suggest that TBT may constitute a risk factor for cardiovascular diseases. Hence, the main purpose of this study was to investigate in human umbilical artery (HUA) the effect of TBT on vascular reactivity, manly in serotonin (5-HT) and histamine receptors. Using standard organ bath techniques, rings of HUA without endothelium were contracted by 5-HT and histamine. We also investigated the effect of TBT on the expression of the receptors using Real-time PCR. The results show that TBT short term effects include concentration-dependent relaxation...
March 23, 2018: Toxicology in Vitro: An International Journal Published in Association with BIBRA
https://www.readbyqxmd.com/read/29573372/mixotrophic-metabolism-by-natural-communities-of-unicellular-cyanobacteria-in-the-western-tropical-south-pacific-ocean
#18
Solange Duhamel, France Van Wambeke, Dominique Lefevre, Mar Benavides, Sophie Bonnet
Cyanobacteria are major contributors to ocean biogeochemical cycling. However, mixotrophic metabolism and the relative importance of inorganic and organic carbon assimilation within the most abundant cyanobacteria are still poorly understood. We explore the ability of Prochlorococcus and Synechococcus to assimilate organic molecules with variable C:N:P composition and its modulation by light availability and photosynthetic impairment. We used a combination of radiolabeled molecules incubations with flow cytometry cell sorting to separate picoplankton groups from the western tropical south Pacific Ocean...
March 24, 2018: Environmental Microbiology
https://www.readbyqxmd.com/read/29563339/germline-mutations-in-the-alternative-pathway-of-complement-predispose-to-hellp-syndrome
#19
Arthur J Vaught, Evan M Braunstein, Jagar Jasem, Xuan Yuan, Igor Makhlin, Solange Eloundou, Andrea C Baines, Samuel A Merrill, Shruti Chaturvedi, Karin Blakemore, C John Sperati, Robert A Brodsky
BACKGROUND: HELLP (hemolysis, elevated liver enzymes, and low platelets) syndrome is a severe variant of hypertensive disorders of pregnancy affecting approximately 1% of all pregnancies, and has significant maternal and fetal morbidity. Previously, we showed that upregulation of the alternative pathway of complement (APC) plays a role in HELLP syndrome. We hypothesize that HELLP syndrome follows a 2-hit disease model similar to atypical hemolytic uremic syndrome (aHUS), requiring both genetic susceptibility and an environmental risk factor...
March 22, 2018: JCI Insight
https://www.readbyqxmd.com/read/29554340/mortality-causes-and-trends-associated-with-giant-cell-arteritis-analysis-of-the-french-national-death-certificate-database-1980-2011
#20
Achille Aouba, Solange Gonzalez Chiappe, Mireille Eb, Claire Delmas, Hubert de Boysson, Boris Bienvenu, Grégoire Rey, Alfred Mahr
Objectives: Comprehensive analyses of cause-specific death patterns in GCA are sparse. We studied the patterns and time trends in GCA-related mortality using a large death certificate database. Methods; We obtained multiple-cause-of-death data from the French national death certificate database for 1980-2011. GCA-associated deaths were defined as decedents ⩾55 years old with GCA listed as an underlying or non-underlying cause of death. Time trends of death rates were analysed and the mean age at death with GCA and in the general population ⩾55 years old were calculated...
March 14, 2018: Rheumatology
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