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https://www.readbyqxmd.com/read/29451611/factors-associated-with-hiv-co-infection-in-cases-of-acquired-syphilis-reported-in-a-reference-center-for-sexually-transmitted-diseases-and-aids-in-the-municipality-of-s%C3%A3-o-paulo-brazil-2014
#1
Carla Gianna Luppi, Solange Eduardo Chabu Gomes, Roberto José Carvalho da Silva, Amanda Miyako Ueno, Anna Maria Kamimura Dos Santos, Ângela Tayra, Renata Ferreira Takahashi
OBJECTIVE: to describe sociodemographic and behavioral characteristics and to identify factors associated with human immunodeficiency virus (HIV) co-infection in cases of acquired syphilis reported in a Reference Center for Sexually Transmitted Diseases (STD) and AIDS. METHODS: cross-sectional study with secondary data from a Reference Center for STD and AIDS in the municipality of São Paulo, Brazil, in 2014; the Poisson regression was used to estimate prevalence ratios (PR) and 95% confidence intervals (95%CI)...
2018: Epidemiologia e Servicos de Saude: Revista do Sistema Unico de Saude do Brasil
https://www.readbyqxmd.com/read/29451584/exposure-to-violence-associations-with-psychiatric-disorders-in-brazilian-youth
#2
Thiago M Fidalgo, Zila M Sanchez, Sheila C Caetano, Solange Andreoni, Adriana Sanudo, Qixuan Chen, Sílvia S Martins
OBJECTIVE: The effects of exposure to violent events in adolescence have not been sufficiently studied in middle-income countries such as Brazil. The aims of this study are to investigate the prevalence of psychiatric disorders among 12-year-olds in two neighborhoods with different socioeconomic status (SES) levels in São Paulo and to examine the influence of previous violent events and SES on the prevalence of psychiatric disorders. METHODS: Students from nine public schools in two neighborhoods of São Paulo were recruited...
February 15, 2018: Revista Brasileira de Psiquiatria
https://www.readbyqxmd.com/read/29446437/effects-of-total-fat-intake-on-bodyweight-in-children
#3
REVIEW
Celeste E Naude, Marianne E Visser, Kim A Nguyen, Solange Durao, Anel Schoonees
BACKGROUND: As part of efforts to prevent childhood overweight and obesity, we need to understand the relationship between total fat intake and body fatness in generally healthy children. OBJECTIVES: To assess the effects of total fat intake on measures of weight and body fatness in children and young people not aiming to lose weight. SEARCH METHODS: For this update we revised the previous search strategy and ran it over all years in the Cochrane Library, MEDLINE (Ovid), MEDLINE (PubMed), and Embase (Ovid) (current to 23 May 2017)...
February 15, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29442306/protective-effect-of-uncaria-tomentosa-extract-against-oxidative-stress-and-genotoxicity-induced-by-glyphosate-roundup%C3%A2-using-zebrafish-danio-rerio-as-a-model
#4
Glaucia Dal Santo, Alan Grotto, Aline A Boligon, Bárbara Da Costa, Cassiano L Rambo, Emily A Fantini, Elisa Sauer, Luan M V Lazzarotto, Kanandra T Bertoncello, Osmar Tomazelli Júnior, Solange C Garcia, Anna M Siebel, Denis B Rosemberg, Jacir Dal Magro, Greicy M M Conterato, Leila Zanatta
Oxidative stress and DNA damage are involved in the glyphosate-based herbicide toxicity. Uncaria tomentosa (UT; Rubiaceae) is a plant species from South America containing bioactive compounds with known beneficial properties. The objective of this work was to evaluate the antioxidant and antigenotoxic potential of UT extract in a model of acute exposure to glyphosate-Roundup® (GR) in zebrafish (Danio rerio). We showed that UT (1.0 mg/mL) prevented the decrease of brain total thiols, the increase of lipid peroxidation in both brain and liver, and the decrease of liver GPx activity caused after 96 h of GR (5...
February 13, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29436396/rapid-activation-of-tumor-associated-macrophages-boosts-preexisting-tumor-immunity
#5
Sabine Hoves, Chia-Huey Ooi, Carsten Wolter, Hadassah Sade, Stefan Bissinger, Martina Schmittnaegel, Oliver Ast, Anna M Giusti, Katharina Wartha, Valeria Runza, Wei Xu, Yvonne Kienast, Michael A Cannarile, Hyam Levitsky, Solange Romagnoli, Michele De Palma, Dominik Rüttinger, Carola H Ries
Depletion of immunosuppressive tumor-associated macrophages (TAMs) or reprogramming toward a proinflammatory activation state represent different strategies to therapeutically target this abundant myeloid population. In this study, we report that inhibition of colony-stimulating factor-1 receptor (CSF-1R) signaling sensitizes TAMs to profound and rapid reprogramming in the presence of a CD40 agonist before their depletion. Despite the short-lived nature of macrophage hyperactivation, combined CSF-1R+CD40 stimulation of macrophages is sufficient to create a proinflammatory tumor milieu that reinvigorates an effective T cell response in transplanted tumors that are either responsive or insensitive to immune checkpoint blockade...
February 7, 2018: Journal of Experimental Medicine
https://www.readbyqxmd.com/read/29432711/seroprevalence-of-human-cysticercosis-in-jata%C3%A3-goi%C3%A3-s-state-brazil
#6
Kaliny Xavier da Guarda, Julia Maria Costa Cruz, Ivanildes Solange da Costa Barcelos
The Taenia solium cysticercosis affects millions of people worldwide and is considered a public health problem, especially in developing countries. The diagnosis of neurocysticercosis (NCC) is complex and involves the analysis of epidemiological, clinical, neuroimaging, and immunological host data. NCC is endemic in Brazil, and is related to the cause of death mainly in the Southeast, South, and Central-West regions. The objective of this study was to determine the seroprevalence of cysticercosis in inhabitants of the city of Jataí, Goiás, in the Central-West region of Brazil from April to August 2012...
February 9, 2018: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29426557/-patients-taking-an-active-role-in-their-care-in-ambulatory-knee-replacement-surgery
#7
REVIEW
Sabrina Rubin, Solange Franger, Adeline Martin, Régis Lorguilloux, Farid Kneife
National recommendations encourage the development of ambulatory surgery. This form of treatment, reserved mainly for short procedures, can also be used for more complex operations such as a total knee replacement. The teams at Vitré general hospital share their experience and emphasise the need to ensure the compliance of patients and their family.
February 2018: Revue de L'infirmière
https://www.readbyqxmd.com/read/29425371/an-analysis-of-methods-used-to-synthesize-evidence-and-grade-recommendations-in-food-based-dietary-guidelines
#8
Phillipa Blake, Solange Durão, Celeste E Naude, Lisa Bero
Evidence-informed guideline development methods underpinned by systematic reviews ensure that guidelines are transparently developed, free from overt bias, and based on the best available evidence. Only recently has the nutrition field begun using these methods to develop public health nutrition guidelines. Given the importance of following an evidence-informed approach and recent advances in related methods, this study sought to describe the methods used to synthesize evidence, rate evidence quality, grade recommendations, and manage conflicts of interest (COIs) in national food-based dietary guidelines (FBDGs)...
February 7, 2018: Nutrition Reviews
https://www.readbyqxmd.com/read/29422032/risk-factors-associated-with-cluster-size-of-mycobacterium-tuberculosis-mtb-of-different-rflp-lineages-in-brazil
#9
Renata Lyrio Peres, Solange Alves Vinhas, Fabíola Karla Correa Ribeiro, Moisés Palaci, Thiago Nascimento do Prado, Bárbara Reis-Santos, Eliana Zandonade, Philip Noel Suffys, Jonathan E Golub, Lee W Riley, Ethel Leonor Maciel
BACKGROUND: Tuberculosis (TB) transmission is influenced by patient-related risk, environment and bacteriological factors. We determined the risk factors associated with cluster size of IS6110 RFLP based genotypes of Mycobacterium tuberculosis (Mtb) isolates from Vitoria, Espirito Santo, Brazil. METHODS: Cross-sectional study of new TB cases identified in the metropolitan area of Vitoria, Brazil between 2000 and 2010. Mtb isolates were genotyped by the IS6110 RFLP, spoligotyping and RDRio...
February 8, 2018: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29412471/untargeted-profiling-of-glycyrrhiza-glabra-extract-with-comprehensive-two-dimensional-liquid-chromatography-mass-spectrometry-using-multi-segmented-shift-gradients-in-the-second-dimension-expanding-the-metabolic-coverage
#10
Yong Foo Wong, Francesco Cacciola, Soraya Fermas, Solange Riga, Darryl James, Valeria Manzin, Brice Bonnet, Philip John Marriott, Paola Dugo, Luigi Mondello
Metabolic profiling of Glycyrrhiza glabra using comprehensive two-dimensional liquid chromatography (LC × LC) coupled with photodiode array (PDA) and mass spectrometry (MS) detection is described. The separation was conducted under reversed-phase conditions, using a combination of first dimension (1 D) 150 mm microbore cyano column utilising 2.7 μm diameter (dp ) particles, and second dimension (2 D) 50 mm superficially porous octadecylsilica column with 2.7 μm dp particles. A multi-segmented shift gradient (MSG) for the 2 D separation was developed, and the orthogonality achieved was compared with other modes of gradients, such as full in-fraction, and shift gradient systems...
February 7, 2018: Electrophoresis
https://www.readbyqxmd.com/read/29396198/morphodifferentiation-of-gen%C3%A3-s-organ-in-engorged-amblyomma-sculptum-berlese-1888-female-ticks-acari-ixodidae
#11
Marcelo Francisco Dos Santos, Magna Aparecida Maltauro Soares, Maria Anete Lallo, Darci Moraes Barros-Battesti, Solange de Lima-Netto, Diva Denelle Spadacci-Morena
The Gené's organ (GO) secretes a waxy substance on eggs that reduces water loss and has antimicrobial properties. The current study evaluated morphological and histochemical aspects of GO in Amblyomma sculptum from the period of post-feeding - when ticks detach from the host - to the stage just before oviposition. In this species, GO is composed of a corpus and two pairs of glands, namely, cranial and caudal. Glandular cells are joined laterally by a system of interdigitating membranes with junctional complexes...
January 29, 2018: Ticks and Tick-borne Diseases
https://www.readbyqxmd.com/read/29385118/brief-interventions-to-promote-behavioral-change-in-primary-care-settings-a-review-of-their-effectiveness-for-smoking-alcohol-and-physical-inactivity
#12
REVIEW
Andrés Rosembaun, Pedro Rojas, María Victoria Rodriguez, Nicolás Barticevic, Solange Rivera Mercado
The brief intervention is a therapeutic strategy suggested to address behavioral changes associated with risk factors for chronic non-communicable diseases and there is ample evidence of its effectiveness. However, this evidence is sustained by various definitions of “brief intervention”, a fact that makes the clinical application of this strategy difficult. This literature review article aimed to conduct a search for systematic reviews in the Epistemonikos database in order to identify common factors in the definition of “brief intervention” and summarize some brief intervention strategies frequently used in primary health care...
January 29, 2018: Medwave
https://www.readbyqxmd.com/read/29380393/leishmania-amazonensis-induces-modulation-of-costimulatory-and-surface-markers-molecules-in-human-macrophages
#13
Solange Dos Santos Costa, Márcia Cristina Fornazim, Alexandre Eduardo Nowill, Selma Giorgio
Manipulation of costimulatory and surface molecules that shape the extent of immune responses by Leishmania is suggested as one of the mechanisms of evading the host's defenses. The experiments reported here were designed to evaluate the expression of CD11b, CD11c, CD14, CD18, CD54, CD80, CD86, CD206, MHC class II and TLR-2 (Toll-like receptor 2) in human macrophages infected with L. amazonensis. Phenotypic evaluation revealed a negative modulation in CD11b, CD11c, CD14, CD18, CD54 and MHC class II molecules, depending on the level of infection...
January 30, 2018: Parasite Immunology
https://www.readbyqxmd.com/read/29377761/ozone-treatment-to-reduce-deoxynivalenol-don-and-zearalenone-zen-contamination-in-wheat-bran-and-its-impact-on-nutritional-quality
#14
Allana Patrícia Santos Alexandre, Rafael Segundo Vela-Paredes, Amanda Silva Santos, Naiara Silva Costa, Solange Guidolin Canniatti-Brazaca, Maria Antonia Calori-Domingues, Pedro Esteves Duarte Augusto
Wheat bran is an important source for human and animal feed. Its nutritional aspects include a high content of fiber and minerals, as well as phenolic compounds that help prevent chronic diseases. However, wheat can be susceptible to contamination by fungus, which can produce mycotoxins such as deoxynivalenol (DON) and zearalenone (ZEN), causing adverse health effects. Therefore, methods should be developed to reduce possible contamination. Ozone can be used for this purpose as it is considered safe and environmentally friendly...
January 29, 2018: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://www.readbyqxmd.com/read/29374079/tlr7-escapes-x-chromosome-inactivation-in-immune-cells
#15
Mélanie Souyris, Claire Cenac, Pascal Azar, Danièle Daviaud, Astrid Canivet, Solange Grunenwald, Catherine Pienkowski, Julie Chaumeil, José E Mejía, Jean-Charles Guéry
Toll-like receptor 7 (TLR7) is critical to the induction of antiviral immunity, but TLR7 dosage is also a key pathogenic factor in systemic lupus erythematosus (SLE), an autoimmune disease with strong female bias. SLE prevalence is also elevated in individuals with Klinefelter syndrome, who carry one or more supernumerary X chromosomes, suggesting that the X chromosome complement contributes to SLE susceptibility. TLR7 is encoded by an X chromosome locus, and we examined here whether the TLR7 gene evades silencing by X chromosome inactivation in immune cells from women and Klinefelter syndrome males...
January 26, 2018: Science Immunology
https://www.readbyqxmd.com/read/29348181/intensity-of-exposure-to-pulmonary-tuberculosis-determines-risk-of-tuberculosis-infection-and-disease
#16
Carlos Acuña-Villaorduña, Edward C Jones-López, Geisa Fregona, Patricia Marques-Rodrigues, Mary Gaeddert, Carolina Geadas, David Jamil Hadad, Laura F White, Lucilia Pereira Dutra Molina, Solange Vinhas, Rodrigo Ribeiro-Rodrigues, Padmini Salgame, Moises Palaci, David Alland, Jerrold J Ellner, Reynaldo Dietze
Household contacts of pulmonary tuberculosis (TB) patients are at increased risk of TB infection and disease. However, their risk in relation to the intensity of exposure remains unknown.We studied smear-positive TB cases and their household contacts in Vitória, Brazil. We collected clinical, demographic and radiographic information from TB cases, and obtained tuberculin skin test (TST) and QuantiFERON-TB Gold (QFT) results from household contacts. We measured intensity of exposure using a proximity score and sleep location in relation to the TB index case and defined infection by TST ≥10 mm or QFT ≥0...
January 2018: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29343840/vision-status-in-older-adults-the-brazilian-amazon-region-eye-survey
#17
Solange R Salomão, Adriana Berezovsky, João M Furtado, Arthur G Fernandes, Sergio Muñoz, Nívea N Cavascan, Marcela C Cypel, Cristina C Cunha, Galton C Vasconcelos, Márcia R K H Mitsuhiro, Paula Y Sacai, Mauro Campos, Paulo H A Morales, Marcos J Cohen, Jacob M Cohen, Sung E S Watanabe, Rubens Belfort
Older adults living in remote areas with limited access to health services are at higher risk to develop visual impairment and blindness. We conducted a population-based survey to determine the vision status in subjects 45 years of age and older from urban and rural areas of Parintins city, Brazilian Amazon Region. Participants underwent ophthalmic examination, including uncorrected (UCVA), presenting (PVA) and best-corrected visual acuity (BCVA). Vision status was described as lines of visual acuity (VA) impairment and lines of VA improvement from UCVA to BCVA and from PVA to BCVA in the better-seeing eye...
January 17, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29336722/perceptions-on-technology-for-volunteer-respite-care-for-bedridden-elders-in-chile
#18
Esmeralda Abarca, Solange Campos, Valeria Herskovic, Carolina Fuentes
PURPOSE:  Informal caregivers of bedridden elders need a respite. One form of obtaining a respite is through volunteers who are contacted by means of information and communication technology (ICT). METHOD:  A qualitative study was carried out in a low-income district in Santiago, Chile, to learn about how caregivers of bedridden elders perceive the possibility of using ICT to access this respite. In-depth interviews were carried out and transcribed verbatim, then analysed using open coding...
December 2018: International Journal of Qualitative Studies on Health and Well-being
https://www.readbyqxmd.com/read/29327673/evaluation-of-the-electromyographic-fatigue-of-the-masseter-and-temporalis-muscles-in-individuals-with-osteoporosis
#19
Veridiana Wanshi Arnoni, Paulo Batista de Vasconcelos, Luiz Gustavo de Sousa, Bruno Ferreira, Marcelo Palinkas, Mariah Acioli Righetti, Gabriel Pádua da Silva, Solange Aparecida Caldeira Monteiro, Simone Cecilio Hallak Regalo, Selma Siéssere
Objectives The objective of this study was to evaluate the electromyographic fatigue of the masseter and temporalis muscles in individuals with and without osteoporosis. Methods Median frequency of the initial, mid, and final periods of the electromyographic signal in the 33 subjects with osteoporosis (OG) and 33 subjects without osteoporosis [control (CG)] was analyzed. Results OG showed a decrease in median frequency along the electromyographic signal, with a significant difference for the right masseter: initial vs...
January 12, 2018: Cranio: the Journal of Craniomandibular Practice
https://www.readbyqxmd.com/read/29320739/variation-in-activity-state-axonal-projection-and-position-define-the-transcriptional-identity-of-individual-neocortical-projection-neurons
#20
Maxime Chevée, Johanna De Jong Robertson, Gabrielle Heather Cannon, Solange Pezon Brown, Loyal Andrew Goff
Single-cell RNA sequencing has generated catalogs of transcriptionally defined neuronal subtypes of the brain. However, the cellular processes that contribute to neuronal subtype specification and transcriptional heterogeneity remain unclear. By comparing the gene expression profiles of single layer 6 corticothalamic neurons in somatosensory cortex, we show that transcriptional subtypes primarily reflect axonal projection pattern, laminar position within the cortex, and neuronal activity state. Pseudotemporal ordering of 1,023 cellular responses to sensory manipulation demonstrates that changes in expression of activity-induced genes both reinforced cell-type identity and contributed to increased transcriptional heterogeneity within each cell type...
January 9, 2018: Cell Reports
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