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https://www.readbyqxmd.com/read/28099596/impact-of-chronic-urticaria-on-the-quality-of-life-of-patients-followed-up-at-a-university-hospital
#1
Gabriela Andrade Coelho Dias, Gisele Viana Pires, Solange Oliveira Rodrigues do Valle, Sérgio Duarte Dortas, Soloni Levy, Alfeu Tavares França, Ilaria Baiardini, Walter Giorgio Canonica
BACKGROUND: Chronic urticaria is a debilitating disease that considerably affects health-related quality of life, and the Chronic Urticaria Quality of Life Questionnaire is the only questionnaire specifically designed for its evaluation. OBJECTIVE: To evaluate the quality of life of patients with chronic urticaria, using the Brazilian Portuguese version of the Chronic Urticaria Quality of Life Questionnaire. METHODS: The Chronic Urticaria Quality of Life Questionnaire was self-administered in 112 chronic urticaria patients and disease activity was assessed through the Urticaria Activity Score...
November 2016: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/28099383/a-case-of-a-gunshot-wound-to-the-fetus-in-utero
#2
Mitchell R Ladd, Kathryn Shaw, Sara Munoz-Blanco, Maureen Gilmore, Sandra DiBrito, Solange N Eloundou, Kent Stevens, Isam W Nasr, Dylan Stewart, Robert E Falcone
No abstract text is available yet for this article.
January 17, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28094393/correction-copper-ii-catalyzed-synthesis-of-novel-helical-luminescent-benzo-4-5-imidazo-1-2-a-1-10-phenanthrolines-via-an-intramolecular-c-h-amination-reaction
#3
Ramon Borges da Silva, Rodolfo Inêz Teixeira, James L Wardell, Solange M S V Wardell, Simon J Garden
Correction for 'Copper(ii) catalyzed synthesis of novel helical luminescent benzo[4,5]imidazo[1,2-a][1,10]phenanthrolines via an intramolecular C-H amination reaction' by Ramon Borges da Silva, et al., Org. Biomol. Chem., 2017, DOI: 10.1039/c6ob02508k.
January 17, 2017: Organic & Biomolecular Chemistry
https://www.readbyqxmd.com/read/28092859/n-2-arylmethylimino-ethyl-7-chloroquinolin-4-amine-derivatives-synthesized-by-thermal-and-ultrasonic-means-are-endowed-with-anti-zika-virus-activity
#4
Giselle Barbosa-Lima, Ligia S da Silveira Pinto, Carlos R Kaiser, James L Wardell, Caroline S De Freitas, Yasmine R Vieira, Andressa Marttorelli, José Cerbino Neto, Patrícia T Bozza, Solange M S V Wardell, Marcus V N de Souza, Thiago M L Souza
Zika virus (ZIKV), an emerging Flavivirus, was recently associated with severe neurological complications and congenital diseases. Therefore, development of antiviral agents capable of inhibiting ZIKV replication is urgent. Chloroquine is a molecule with a confirmed safety history for use with pregnant women, and has been found to exhibit anti-ZIKV activity at concentrations around 10 μM. This suggests that modifications to the chloroquine structure could be promising for obtaining more effective anti-ZIKV agents...
January 6, 2017: European Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28088249/interactions-of-human-microglia-cells-with-japanese-encephalitis-virus
#5
Nils Lannes, Viviane Neuhaus, Brigitte Scolari, Solange Kharoubi-Hess, Michael Walch, Artur Summerfield, Luis Filgueira
BACKGROUND: Japanese encephalitis virus (JEV) is a neurotropic flavivirus causing mortality and morbidity in humans. Severe Japanese encephalitis cases display strong inflammatory responses in the central nervous system and an accumulation of viral particles in specific brain regions. Microglia cells are the unique brain-resident immune cell population with potent migratory functions and have been proposed to act as a viral reservoir for JEV. Animal models suggest that the targeting of microglia by JEV is partially responsible for inflammatory reactions in the brain...
January 14, 2017: Virology Journal
https://www.readbyqxmd.com/read/28078776/performance-of-the-forenseq-tm-dna-signature-prep-kit-on-highly-degraded-samples
#6
Paolo Fattorini, Carlo Previderé, Ilaria Carboni, Giorgio Marrubini, Solange Sorçaburu-Cigliero, Pierangela Grignani, Barbara Bertoglio, Paolo Vatta, Ugo Ricci
Next generation sequencing (NGS) is the emerging technology in forensic genomics laboratories. It offers higher resolution to address most problems of human identification, greater efficiency and potential ability to interrogate very challenging forensic casework samples. In the present study, a trial set of DNA samples was artificially degraded, by progressive aqueous hydrolysis, and analyzed together with the corresponding unmodified DNA sample and control sample 2800M, to test the performance and reliability of the ForenSeq(TM) DNA Signature Prep kit using the MiSeq Sequencer (Illumina)...
January 12, 2017: Electrophoresis
https://www.readbyqxmd.com/read/28076609/rotation-of-the-second-cervical-vertebra-in-pediatric-patient
#7
Priscila Dias Peyneau, Gina Delia Roque-Torres, Luiz Roberto Godolfim, Eliana Dantas da Costa, Solange Maria de Almeida, Gláucia Maria Bovi Ambrosano
No abstract text is available yet for this article.
October 2016: Einstein
https://www.readbyqxmd.com/read/28076567/full-field-electroretinogram-recorded-with-skin-electrodes-in-normal-adults
#8
Arthur Gustavo Fernandes, Solange Rios Salomão, Josenilson Martins Pereira, Adriana Berezovsky
Purpose: Alternative recording methods have been tested to allow the electroretinogram (ERG) recording in uncooperative patients and/or patients with palpebral alterations, including recordings with skin electrodes. The purpose of this study was to compare ERG recorded with skin electrodes and well-established microfiber electrodes and to determine normative values of ERG parameters for recording with skin electrodes. Methods: Fifty healthy volunteers (17-26 years; mean 20...
November 2016: Arquivos Brasileiros de Oftalmologia
https://www.readbyqxmd.com/read/28073388/isolation-and-biological-and-molecular-characterization-of-neospora-caninum-nc-sp1-from-a-naturally-infected-adult-asymptomatic-cattle-bos-taurus-in-the-state-of-s%C3%A3-o-paulo-brazil
#9
Solange Oliveira, Rodrigo Martins Soares, Juliana Aizawa, Herbert Sousa Soares, Daniela Pontes Chiebao, Luis Miguel Ortega-Mora, Javier Regidor-Cerrillo, Natália Quadros Bressa Silva, Solange Maria Gennari, Hilda Fátima Jesus Pena
The biological and genetic diversity of Neospora caninum is very limited because of availability of only a few viable isolates worldwide. This study describes the isolation and biological and molecular characterization of a new viable isolate of N. caninum (NC-SP1), from a cattle in Brazil. Approximately 400 g of brain from a naturally infected adult male cattle from an abattoir was fed to a 2-month-old dog. Neospora-like oocysts were observed on day 7 post-inoculation (PI) and the duration of oocyst shedding was 14 days...
January 11, 2017: Parasitology
https://www.readbyqxmd.com/read/28068989/long-lasting-insecticidal-net-llin-ownership-use-and-cost-of-implementation-after-a-mass-distribution-campaign-in-kasa%C3%A3-occidental-province-democratic-republic-of-congo
#10
Henry Maggi Ntuku, Laura Ruckstuhl, Jean-Emmanuel Julo-Réminiac, Solange E Umesumbu, Alain Bokota, Antoinette Kitoto Tshefu, Christian Lengeler
BACKGROUND: Long-lasting insecticidal nets (LLIN) are a highly effective means for preventing malaria infection and reducing associated morbidity and mortality. Mass free distribution campaigns have been shown to rapidly increase LLIN ownership and use. Around 3.5 million LLINs were distributed free of charge in the Kasaï Occidental Province in the Democratic Republic of Congo (DRC) in September-October 2014, using two different approaches, a fixed delivery strategy and a door-to-door strategy including hang-up activities...
January 9, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28063735/nephrotic-syndrome-in-small-cell-lung-cancer-and-induction-of-c-mip-in-podocytes
#11
Yassine Bouatou, Thibaud Koessler, Julie Oniszczuk, Shao-Yu Zhang, Solange Moll, Vincent Audard, Sophie de Seigneux, Djillali Sahali
Paraneoplastic nephrotic syndrome is often a complication in patients with cancer, and various histologic lesions have been described in the kidney. We report the case of a 76-year-old woman who presented with a podocytopathy that was found to be associated with a small cell lung carcinoma (SCLC). One cycle of carboplatin-etoposide combination therapy led to resolution of nephrotic syndrome and remission of the lung carcinoma. C-Maf-inducing protein (C-Mip) was overexpressed in both podocytes and cancer cells, but was not found in control kidney and lung tissue samples...
January 4, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28059670/mycobacterial-hsp65-antigen-upregulates-the-cellular-immune-response-of-healthy-individuals-compared-to-tuberculosis-patients
#12
Pryscilla Fanini Wowk, Luís Henrique Franco, Denise Morais Fonseca, Marina Oliveira Paula, Élcio Dos Santos Oliveira Vianna, Ana Paula Wendling, Valéria Maria Augusto, Silvana Maria Elói-Santos, Andréa Teixeira-Carvalho, Flávia Dias Coelho Silva, Solange Alves Vinhas, Olindo Assis Martins-Filho, Moisés Palaci, Célio Lopes Silva, Vânia Luiza Deperon Bonato
Previously we showed that 65-kDa Mycobacterium leprae heat shock protein (Hsp65) is a target for the development of a tuberculosis vaccine. Here we evaluated peripheral blood mononuclear cells (PBMC) from healthy individuals or tuberculosis patients stimulated with two forms of Hsp65 antigen, recombinant DNA that encodes Hsp65 (DNA-HSP65) or recombinant Hsp65 protein (rHsp65) in attempting to mimic a prophylactic or therapeutic study in vitro, respectively. Proliferation and cytokine-producing CD4(+) or CD8(+) cell were assessed by flow cytometry...
January 6, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/28042916/glucose-homeostasis-abnormalities-among-cameroon-patients-with-newly-diagnosed-hypertension
#13
Félicité Kamdem, Daniel Lemogoum, Marie-Solange Doualla, Fernando Kemta Lepka, Elvis Temfack, Yvette Ngo Nouga, Caroline Kenmegne, Henry Luma, Michel P Hermans
The authors assessed the frequency of glucose homeostasis abnormalities among 839 Cameroonians with newly diagnosed hypertension (mean age: 50.8±11 years; 49.9% female) in a cross-sectional survey conducted at the Douala General Hospital, Douala, Cameroon. In all participants, blood pressure, fasting plasma glucose (FPG), and lipids were recorded. Impaired fasting glycemia was described as an FPG level between 100 and 125 mg/dL and provisional diabetes as an FPG level ≥126 mg/dL. The FPG was 101±30 mg/dL...
January 2, 2017: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/28040217/impacts-of-converting-low-intensity-pastureland-to-high-intensity-bioenergy-cropland-on-the-water-quality-of-tropical-streams-in-brazil
#14
Ricardo Hideo Taniwaki, Carla Cristina Cassiano, Solange Filoso, Silvio Frosini de Barros Ferraz, Plínio Barbosa de Camargo, Luiz Antônio Martinelli
In Brazil, the cultivation of bioenergy crops is expanding at an accelerated rate. Most of this expansion has occurred over low-intensity pasture and is considered sustainable because it does not involve deforestation of natural vegetation. However, the impacts on the water quality of headwater streams are poorly understood, especially with regard to the influence of land use patterns in the watershed. In this study, we investigated the effects of land-use conversion on the water quality of streams draining sugarcane fields and examined whether the preservation of forested areas at the top of the headwaters would help mitigate the negative impacts of intensive agriculture...
December 28, 2016: Science of the Total Environment
https://www.readbyqxmd.com/read/28029409/serum-concentrations-and-gene-expression-of-sirtuin-1-in-healthy-and-slightly-overweight-subjects-after-caloric-restriction-or-resveratrol-supplementation-a-randomized-trial
#15
Antonio P Mansur, Alessandra Roggerio, Marisa F S Goes, Solange D Avakian, Dalila P Leal, Raul C Maranhão, Célia M C Strunz
BACKGROUND: Sirtuin 1 (Sirt1) plays an important role in vascular biology, and influences aspects of age-dependent atherosclerosis. In animals, the sirtuin system is strongly influenced by resveratrol and caloric restriction, but its expression in humans is controversial. This study investigated the effects of resveratrol and caloric restriction on Sirt1 serum concentrations and vascular biomarkers in a healthy human population. METHODS AND RESULTS: Forty-eight healthy participants (24 women) aged 55-65years were randomized to either 30days of resveratrol administration (500mg/day) or caloric restriction (1000cal/day)...
October 27, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/28027659/oral-rivaroxaban-for-the-treatment-of-symptomatic-venous-thromboembolism-in-400-patients-with-active-cancer
#16
Bruno Soriano Pignataro, Kenji Nishinari, Rafael Noronha Cavalcante, Guilherme Centofanti, Guilherme Yazbek, Mariana Krutman, Guilherme Andre Zotelle Bomfim, Igor Yoshio Imagawa Fonseca, Marcelo Passos Teivelis, Nelson Wolosker, Solange Moraes Sanches, Eduardo Ramacciotti
PURPOSE: To study the safety and efficacy of rivaroxaban-a direct oral anticoagulant-use in patients with active cancer and venous thromboembolism (VTE). PATIENTS AND METHODS: Retrospective cohort study of 400 patients with active cancer and associated VTE, defined as deep venous thrombosis and/or pulmonary embolism. This single-center study was carried out from January 2012 to June 2015. The aim of this study was to determine the efficacy and safety, using the incidence of recurrent symptomatic VTE and major bleeding, respectively, throughout the treatment with rivaroxaban...
January 1, 2016: Clinical and Applied Thrombosis/hemostasis
https://www.readbyqxmd.com/read/28017787/randomized-phase-iii-trial-of-erlotinib-versus-docetaxel-in-patients-with-advanced-squamous-cell-non-small-cell-lung-cancer-failing-first-line-platinum-based-doublet-chemotherapy-stratified-by-veristrat-good-versus-veristrat-poor-the-european-thoracic-oncology
#17
Solange Peters, Rolf A Stahel, Urania Dafni, Santiago Ponce Aix, Bartomeu Massutí, Oliver Gautschi, Linda Coate, Ana López Martín, Robbert van Heemst, Thierry Berghmans, Peter Meldgaard, Manuel Cobo Dols, Javier Garde Noguera, Alessandra Curioni-Fontecedro, Daniel Rauch, Michael T Mark, Sinead Cuffe, Bonne Biesma, Arjen Mj van Henten, Óscar Juan Vidal, Ramón Palmero Sanchez, José Carlos Villa Guzmán, Ricardo Collado Martin, Sergio Peralta, Amelia Insa, Yvonne Summers, István Láng, Anne Horgan, Fortunato Ciardiello, Sander de Hosson, Remge Pieterman, Harry Jm Groen, Paul M van den Berg, Christoph C Zielinski, Yojena Chittazhathu Kurian Kuruvilla, Adriana Gasca-Ruchti, Marie Kassapian, Silvia Novello, Valter Torri, Zoi Tsourti, Vanesa Gregorc, Egbert F Smit
INTRODUCTION: Docetaxel and erlotinib are registered second-line treatments for wild-type EGFR NSCLC. Previous studies suggested a predictive value of the Veristrat test in second-line therapy of NSCLC, classifying patients as either Veristrat "good" or "poor". EMPHASIS-lung aimed at exploring this predictive effect in patients with squamous cell NSCLC. The trial closed prematurely due to low accrual and results from other trials. Our analysis includes an exploratory combined analysis with results from the PROSE trial...
December 22, 2016: Journal of Thoracic Oncology
https://www.readbyqxmd.com/read/28010923/biomonitoring-of-gasoline-station-attendants-exposed-to-benzene-effect-of-gender
#18
Angela M Moro, Natália Brucker, Mariele F Charão, Marília Baierle, Elisa Sauer, Gabriela Goethel, Anelise Barth, Sabrina N Nascimento, Bruna Gauer, Juliano Durgante, Beatriz S Amaral, Francisco R A Neto, Adriana Gioda, Solange C Garcia
Women are employed in increasing numbers as gasoline station attendants, a work category with risk of exposure to benzene. We have assessed the effect of gender on biomarkers of occupational benzene exposure. Gasoline station attendants (20 men and 20 women) and 40 control individuals (20 men and 20 women) with no history of occupational benzene exposure were evaluated. Benzene exposure was monitoring by environmental and biological measurements. Urinary trans,trans-muconic acid levels, well-known genetic and hematological alterations linked to benzene exposure, and non-cancer effects on the immune, hepatic, and renal systems were investigated...
January 2017: Mutation Research
https://www.readbyqxmd.com/read/28004258/hints-for-control-of-infection-in-unique-extrahepatic-vertebral-alveolar-echinococcosis
#19
Jean-François Faucher, Cécile Descotes-Genon, Bruno Hoen, Joël Godard, Sophie Félix, Sébastien Aubry, Oleg Blagosklonov, Frédéric Grenouillet, Marie-Pascale Brientini, Carine Richou, Solange Bresson-Hadni, Catherine Chirouze
The prognosis of vertebral alveolar echinococcosis (AE) is poor. We report on the unique outcome of a patient with preexisting liver cirrhosis, in whom a diagnosis of vertebral AE was established on vertebral histopathology (D4 corporectomy in 2010 for paraplegia). Therapeutic drug monitoring of albendazole (ABZ) showed that a low dosage was appropriate. The patient recovered and ABZ withdrawal was decided in 2014, with no relapse 18 months later. In this patient, infection was purely or mainly localized in the dorsal spine, and this may have been favored by liver cirrhosis...
December 21, 2016: Infection
https://www.readbyqxmd.com/read/28002781/performance-of-aerobic-nitrite-granules-treating-an-anaerobic-pre-treated-wastewater-originating-from-the-potato-industry
#20
Thomas Dobbeleers, Dominique Daens, Solange Miele, Jolien D'aes, Michel Caluwé, Luc Geuens, Jan Dries
In this study nitrogen removal via nitrite >80% was achieved after approximately 80days in a sequencing batch reactor (SBR) treating pre-treated industrial wastewater originating from the potato industry. Thereafter, SBR performance was investigated during the formation of aerobic nitrite granules (ANG). The first granules appeared after 26days leading to full granulation after 64days. ANG showed excellent settling properties, as the Sludge Volume Index (SVI) went down to 16mL/g and a SVI10/SVI30=1 was obtained...
December 7, 2016: Bioresource Technology
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